Los Angeles Rams on NBC Sunday Night Football, Prescott threw for 266 yards and a touchdown and rushed for 30 yards as the Cowboys lost 20–17. In Week 2 against the Atlanta Falcons, Prescott threw for 450 passing yards and a touchdown, and rushed for three additional touchdowns to help the Cowboys win 40–39. At one point during the game, the Falcons had a twenty-point lead over the Cowboys, but Prescott's four second half touchdowns aided by a successful onside kick and a last-second field goal won the game for the Cowboys. He became the first player in NFL history to pass for at least 400 yards and rush for three touchdowns in the same game. Prescott was named the NFC Offensive Player of the Week for his performance in Week 2. During Week 3 against the Seattle Seahawks, Prescott finished with 472 passing yards, three touchdowns, and two interceptions as the Cowboys lost 38–31. During Week 4 against the Cleveland Browns, Prescott finished with 502 passing yards, four touchdowns, an interception, and a lost fumble as the Cowboys lost 49–38. He became the first player in NFL history to pass for at least 450 yards in three consecutive games. In Week 5 against the New York Giants, Prescott suffered an injury to his right ankle, and was carted off the field. He completed 14 passes for 166 yards and an interception plus had a receiving touchdown before leaving. It was revealed that he had suffered a compound fracture and dislocation to his right ankle, and he underwent surgery the same night, ending his season. Prescott was placed on season-ending injured reserve on October 19, 2020. 2021 season The Cowboys placed the exclusive franchise tag on Prescott for the second consecutive season on March 9, 2021, and he signed a four-year contract extension with the Cowboys the next day for $160 million with $126 million guaranteed. The deal included a $66 million signing bonus, the highest in NFL history. In June 2021, he left Adidas and signed a five-year deal with Jordan. In his first game back from his injury in Week 1 against the Tampa Bay Buccaneers, Prescott threw for 403 yards, three touchdowns, and an interception in a 31–29 loss. In Week 6, Prescott threw for 445 yards, three touchdowns, and one interception in a 35–29 overtime win over the New England Patriots. His performance earned him NFC