by far, the most recommended drug regimen for medical abortions, but other drug combinations are available. Misoprostol alone, without mifepristone, may be used in some circumstances for medical abortion, and has even been demonstrated to be successful in the second trimester. Misoprostol is more commonly available than mifepristone, and is easier to store and administer, so misoprostol without mifepristone may be suggested by the provider if mifepristone is not available. If misoprostol is used without mifepristone, the WHO recommends 800 μg of misoprostol inside the cheek, under the tongue, or in the vagina. The success rate of misoprostol alone for terminating pregnancy (93%) is nearly the same as the mifepristone-misoprostol combination (96%). However, 15% of the women using misoprostol alone required a surgical follow-up procedure, which is significantly more than the mifepristone-misoprostol combination. A rarely used drug combination for uterine pregnancies is methotrexate-misoprostol, which is typically reserved for ectopic pregnancies. Methotrexate is given either orally or intramuscularly, followed by vaginal misoprostol 3–5 days later. The methotrexate combination is available through 63 days. The WHO authorizes the methotrexate-misoprostol combination but recommends the mifepristone combination because methotrexate may be teratogenic to the embryo in cases of incomplete abortion. The methotrexate-misoprostol combination is considered more effective than misoprostol alone. Access to medical abortion Both drugsmifepristone and misoprostolare no longer covered by drug patents, and hence are available as generic drugs. Over-the-counter availability The requirements for a prescription vary widely between countries. Many countries make the medical abortion drugs available over the counter, without a prescription, such as China, India, and others. Other countries require a prescription (Canada, most of Western Europe, the United States, and others). Some countries require a prescription but are lax about enforcing that requirement (Russia, Brazil, and others). Telehealth access Telehealth includes access to medical services that the person can perform at home, without in-person visits to clinic or provider offices. People who have used telehealth report being satisfied with the access it provides to abortion services. However, those who might need the service the most (those who are incarcerated, unhoused, or live on low income) are often inhibited from accessing it. Telehealth options for people in the U.S. seeking medical abortion include: Aid Access, Plan C, Hey Jane, Choix, Just the Pill, carafem, and Abortion on Demand. Clinic-to-clinic access In this model, a provider communicates with a patient located at another site using clinic-to-clinic videoconferencing to provide medication