morphology and absence of the 13q14-deletion, presence of pRB-negative, and in most cases absence of desmin in the this tumor's neoplastic cells distinguish it from MFB. Treatment Biopsy and analyses of at least a few MFB markers (e.g. pRB, 13q14, CD24, desmim, and estrogen, progesterone, androgen receptors) can strongly indicate the diagnosis of MFB and its variants. Pre-surgical biopsy of the suspect lesion is strongly recommended because surgical treatment of MFB can be less aggressive than the treatments needed for many other tumors. The recommended treatment of MFB and its variants is conservative surgical removal. If indicated by the tumors location, the surgery can leave some neoplastic cells behind: MTF almost never recurs even when not all tumor tissue is removed. Routine post-surgical follow-up should be included in the treatment regimen for MFB. Additional images See also Spindle cell lipoma Breast cancer classification References External links Benign neoplasms Breast diseases Dermal and subcutaneous growths