a park. The Gaslini employs over 2,000 staff including doctors, nurses, academics, and researchers. There are all pediatric specialties, numerous laboratories, and university chairs, many with corresponding professional schools. Since its foundation, the Gaslini has been the seat of the University of Genoa. On average there are a total of 516 beds, about 50 thousand admissions per year (between normal, day hospital, and outpatient treatment), with more than 40 thousand accesses to the emergency department in the 2nd quarter. There are about 600 foreign patients per year, on average from sixty countries of the world. Research Research is a strategic goal of the Institute and is primarily aimed at translating research findings into clinical practice. In 2007–2008, Gaslini Institute received the coveted accreditation recognition of Joint Commission International. In 2019, the agreement between the Giannina Gaslini Institute and the Italian Institute of Technology (IIT) will reach its operational conclusion, particularly in relation to the Joint Lab aspects of genomics, which are aspects of both high-value research and highly specialized complex diagnostics. The Institute shows an increasing number of admissions with appropriateness criteria and a progressive increase in the volume of outpatient activities, day clinics, and day surgery provided in a structure called "Day Hospital". In 2019, 538,704 outpatient services were provided, including 14,742 ordinary admissions and 14,696 cycles of Day Hospital and Day Surgery. Due to its nature as IRCCS, an important mission of the institute is scientific research, the results of which are published in prestigious international journals and aim to translate the latest achievements in pediatrics and pediatric specialties into clinical application. The research activity is carried out within the 5 institutional research lines (PNR 2018-2020): -Innovative Diagnostic Therapeutic Strategies and Rare Diseases. -Pediatric science, surgery, and neonatology -Rheumatology, Immunology, and Autoinflammatory Diseases -Hematology, oncology, and cell therapies -Muscular and neurological diseases Among the outstanding results of Gaslini's research activity are first and foremost the research findings of high scientific value of a translational nature, which, thanks to early and more accurate diagnosis and innovative and very effective therapies, have enabled a real revolution in the treatment and prognosis of high-risk leukemia, disabling rheumatic diseases and severe nephropathies of the child. Notable people Giovanni De Toni (1895-1973) in 1942, he became director of the Istituto Gaslini where he revolutionized the approach to kids' medical care setting up a free ambulatory inside the hospital. He's fame rose during the