It was developed in the Weizmann Institute of Science in Israel by Michael Sela, Ruth Arnon and Deborah Teitelbaum. Development of bioengineered recombinant interferon proteins by Michel Revel from the Weizmann Institute of Science in Israel. Development of taliglucerase alfa (Elelyso), a recombinant glucocerebrosidase enzyme produced from transgenic carrot cell cultures. Taliglucerase alfa won approval from the U.S. Food and Drug Administration in May 2012 as an orphan drug for the treatment of Type 1 Gaucher's disease. Development of engineered recombinant Chimeric Antigen Receptors by Professor Zelig Eshhar of the Weizmann Institute of Science and his trainee Gideon Gross, today a component of novel cell-based immunotherapy for various cancers. Sambucol, an over-the-counter elderberry-based anti-influenza syrup. Discovered by Dr. Madeleine Mumcuoglu at the Hebrew University of Jerusalem. Studies in 1995 showed that Sambucol was effective against human, swine and avian influenza strains, although more research is required to clearly understand its effectiveness. Development of ENvue, a feeding tube placement system with advanced methods of navigation, integrated sensors and body mapping, for accurate enteral tube placement, by the Israeli company ENvizion Medical, used in Hospitals and Medical centers in the US. Economics Work of Daniel Kahneman and Amos Tversky of the Hebrew University of Jerusalem explaining irrational human economic choices. The work led Daniel to receive the Nobel Prize in Economics. Developments in Game theory. Israel Aumann of the Hebrew University of Jerusalem received the Nobel Prize in Economics for his work in this field. The Rubinstein bargaining model, one of the most influential findings in game theory, refers to a class of bargaining games that feature alternating offers through an infinite time horizon. The proof is from Ariel Rubinstein 1982. Biotechnology Nanowire – a conductive wire made of a string of tiny particles of silver, a thousand times thinner than a human hair. Developed by Uri Sivan, Erez Braun and Yoav Eichen from the Technion. World's smallest DNA computing machine system – "the smallest biological computing device" ever constructed, according to Guinness Book of Records, which is composed of enzymes and DNA molecules capable of performing simple mathematical calculations and which uses its input DNA molecule as its sole source of energy. Developed in 2003 in the Weizmann Institute of Science by professor Ehud Shapiro and his team. Theoretical computer science RSA public key encryption, introduced by Adi Shamir with Ron Rivest, and Leonard Adleman The concept of nondeterministic finite automatons,