Cascilla is an unincorporated community located in Tallahatchie County, Mississippi. Cascilla is approximately southeast of Paynes and approximately south of Charleston on Cascilla Road. Although an unincorporated community, Cascilla has a post office and a zip code of 38920. Jamie L. Whitten, the second-longest serving U.S. Representative and the fifth-longest serving member of the U.S. Congress, was born in Cascilla. References Unincorporated communities in Tallahatchie County, Mississippi Unincorporated communities in Mississippi