James Mahoney may refer to: James Mahony (1810–1879), Irish artist and engraver James Mahoney (politician) (1873–1938), British priest and politician James Mahoney (1958–2020), American pulmonologist and internist James Patrick Mahoney (New York bishop) (1925–2002), American bishop James Patrick Mahoney (1927–1995), Canadian bishop James E. Mahoney (1858–1926), United States Marine Corps officer