Bell Centre || 20,904 || 22–13–4 || 48 || |- align="center" bgcolor="ccffcc" | 40 || January 4 || @ Ottawa Senators || 5–3 || || McElhinney || Canadian Tire Centre || 13,914 || 23–13–4 || 50 || |- align="center" bgcolor="ccffcc" | 41 || January 5 || @ Carolina Hurricanes || 3–1 || || Vasilevskiy || PNC Arena || 18,015 || 24–13–4 || 52 || |- align="center" bgcolor="ccffcc" | 42 || January 7 || Vancouver Canucks || 9–2 || || Vasilevskiy || Amalie Arena || 19,092 || 25–13–4 || 54 || |- align="center" bgcolor="ccffcc" | 43 || January 9 || Arizona Coyotes || 4–0 || || Vasilevskiy || Amalie Arena || 19,092 || 26–13–4 || 56 || |- align="center" bgcolor="ccffcc" | 44 || January 11 || @ Philadelphia Flyers || 1–0 || || Vasilevskiy || Wells Fargo Center || 19,866 || 27–13–4 || 58 || |- align="center" bgcolor="ffcccc" | 45 || January 12 || @ New Jersey Devils || 1–3 || || McElhinney || Prudential Center || 14,203 || 27–14–4 || 58 || |- align="center" bgcolor="ccffcc" | 46 || January 14 || Los Angeles Kings || 4–3 || SO || Vasilevskiy || Amalie Arena || 19,092 || 28–14–4 || 60 || |- align="center" bgcolor="ffcccc" | 47 || January 16 || @ Minnesota Wild || 2–3 || || McElhinney || Xcel Energy Center || 17,305 || 28–15–4 || 60 || |- align="center" bgcolor="ccffcc" | 48 || January 17 || @ Winnipeg Jets || 7–1 || || Vasilevskiy || Bell MTS Place || 15,325 || 29–15–4 || 62 || |- align="center" bgcolor="bbbbbb" | colspan="11"|All-Star Break (January 23–26) |- align="center" bgcolor="B0C4DE" | 49 || January 27 || @ Dallas Stars || 2–3 || OT || Vasilevskiy || American Airlines Center || 18,345 || 29–15–5 || 63 || |- align="center" bgcolor="ccffcc" | 50 || January 29 || @ Los Angeles Kings || 4–2 || || Vasilevskiy || Staples Center || 18,230 || 30–15–5 || 65 || |- align="center" bgcolor="ccffcc" | 51 || January 31 || @ Anaheim Ducks || 4–3 || || Vasilevskiy || Honda Center || 16,032 || 31–15–5 || 67 || |- |- align="center" bgcolor="ccffcc" | 52 || February 1 || @ San Jose Sharks || 3–0 || || McElhinney || SAP Center || 17,562 || 32–15–5 || 69 || |- align="center" bgcolor="ccffcc" | 53 || February 4 || Vegas Golden Knights || 4–2 || || Vasilevskiy || Amalie Arena || 19,092 ||