De Francesco (or de Francesco) is an Italian surname. Notable people with this surname include: Alberto De Francesco (born 1994), Italian football player Devlin DeFrancesco (born 2000), Canadian-Italian auto racing driver Francesco De Francesco (born 1977), Italian football striker Joey DeFrancesco (1971–2022), American jazz organist, trumpeter, saxophonist, and occasional singer John DeFrancesco (born 1940), American jazz organist and vocalist Johnny DeFrancesco (born 1965), merican blues guitarist Sebastian de Francesco (born 1981), Italian football striker Matteuccia de Francesco (died 1428), an alleged Italian witch and nun Tony DeFrancesco (born 1963), American baseball coach See also Francesco Di Francesco Italian-language surnames Patronymic surnames Surnames from given names