23 || November 18 || Anaheim || 5–2 || || Holtby || Capital One Arena || 18,573 || 16–3–4 || 36 || |- style="background:#fcc;" | 24 || November 20 || @ NY Rangers || 1–4 || || Holtby || Madison Square Garden || 17,239 || 16–4–4 || 36 || |- style="background:#fff;" | 25 || November 23 || Vancouver || 1–2 || SO || Holtby || Capital One Arena || 18,573 || 16–4–5 || 37 || |- style="background:#cfc;" | 26 || November 27 || Florida || 4–3 || || Holtby || Capital One Arena || 18,573 || 17–4–5 || 39 || |- style="background:#cfc;" | 27 || November 29 || Tampa Bay || 4–3 || OT || Holtby || Capital One Arena || 18,573 || 18–4–5 || 41 || |- style="background:#cfc;" | 28 || November 30 || @ Detroit || 5–2 || || Samsonov || Little Caesars Arena || 19,190 || 19–4–5 || 43 || |- |- style="background:#cfc;" | 29 || December 3 || @ San Jose || 5–2 || || Holtby || SAP Center || 17,562 || 20–4–5 || 45 || |- style="background:#cfc;" | 30 || December 4 || @ Los Angeles || 3–1 || || Samsonov || Staples Center || 16,102 || 21–4–5 || 47 || |- style="background:#cfc;" | 31 || December 6 || @ Anaheim || 3–2 || || Holtby || Honda Center || 15,945 || 22–4–5 || 49 || |- style="background:#fcc;" | 32 || December 9 || Columbus || 2–5 || || Holtby || Capital One Arena || 18,573 || 22–5–5 || 49 || |- style="background:#cfc;" | 33 || December 11 || Boston || 3–2 || || Holtby || Capital One Arena || 18,573 || 23–5–5 || 51 || |- style="background:#cfc;" | 34 || December 14 || @ Tampa Bay || 5–2 || || Samsonov || Amalie Arena || 19,092 || 24–5–5 || 53 || |- style="background:#fcc;" | 35 || December 16 || @ Columbus || 0–3 || || Holtby || Nationwide Arena || 16,602 || 24–6–5 || 53 || |- style="background:#cfc;" | 36 || December 20 || @ New Jersey || 6–3 || || Samsonov || Prudential Center || 15,021 || 25–6–5 || 55 || |- style="background:#cfc;" | 37 || December 21 || Tampa Bay || 3–1 || || Holtby || Capital One Arena || 18,573 || 26–6–5 || 57 || |- style="background:#fcc;" | 38 || December 23 || @ Boston || 3–7 || || Holtby ||