Pernice () is an Italian surname meaning "partridge". Notable people with this surname include: Erich Pernice (1864–1945), German classical archaeologist Gino Pernice (1927–1997), Italian stage, television and film actor Giovanni Pernice (born 1990), Italian dancer and choreographer Hugo Karl Anton Pernice (1829-1901), German gynecologist Joe Pernice (born 1967), American musician Tom Pernice Jr., American golfer