TD Garden || 17,850 || 26–7–5 || 57 || |- style="background:#cfc;" | 39 || December 27 || Columbus || 2–1 || OT || Samsonov || Capital One Arena || 18,573 || 27–7–5 || 59 || |- style="background:#fcc;" | 40 || December 28 || @ Carolina || 4–6 || || Holtby || PNC Arena || 18,680 || 27–8–5 || 59 || |- style="background:#fcc;" | 41 || December 31 || NY Islanders || 3–4 || || Holtby || Capital One Arena || 18,573 || 27–9–5 || 59 || |- |- style="background:#cfc;" | 42 || January 3 || @ Carolina || 4–3 || || Samsonov || PNC Arena || 18,680 || 28–9–5 || 61 || |- style="background:#cfc;" | 43 || January 5 || San Jose || 5–4 || OT || Holtby || Capital One Arena || 18,573 || 29–9–5 || 63 || |- style="background:#cfc;" | 44 || January 7 || Ottawa || 6–1 || || Samsonov || Capital One Arena || 18,573 || 30–9–5 || 65 || |- style="background:#fcc;" | 45 || January 8 || @ Philadelphia || 2–3 || || Holtby || Wells Fargo Center || 18,595 || 30–10–5 || 65 || |- style="background:#fcc;" | 46 || January 11 || New Jersey || 1–5 || || Holtby || Capital One Arena || 18,573 || 30–11–5 || 65 || |- style="background:#cfc;" | 47 || January 13 || Carolina || 2–0 || || Samsonov || Capital One Arena || 18,573 || 31–11–5 || 67 || |- style="background:#cfc;" | 48 || January 16 || New Jersey || 5–2 || || Samsonov || Capital One Arena || 18,573 || 32–11–5 || 69 || |- style="background:#cfc;" | 49 || January 18 || @ NY Islanders || 6–4 || || Samsonov || Nassau Coliseum || 13,917 || 33–11–5 || 71 || |- style="background:#cfc;" | 50 || January 27 || @ Montreal || 4–2 || || Holtby || Bell Centre || 21,302 || 34–11–5 || 73 || |- style="background:#fcc;" | 51 || January 29 || Nashville || 4–5 || || Holtby || Capital One Arena || 18,573 || 34–12–5 || 73 || |- style="background:#cfc;" | 52 || January 31 || @ Ottawa || 5–3 || || Samsonov || Canadian Tire Centre || 14,279 || 35–12–5 || 75 || |- |- style="background:#fcc;" | 53 || February 2 || Pittsburgh || 3–4 || || Samsonov || Capital One Arena || 18,573 || 35–13–5 || 75 || |- style="background:#cfc;" | 54 ||