as well as a political one, and was awarded citizenship of the republic by the Doge in December of that year. In 1409, he attended the synod in Constantinople which condemned the two wayward bishops, Makarios of Ankyra and Matthew of Medeia. He was described as being a Senator during this time. He died of plague in 1410. Family Theodore's wife was Helena Ouresina Doukaina, a daughter of John Uroš, ruler of Thessaly. He is believed to have had the following issue: George Palaiologos Kantakouzenos, "Sachatai" (d. circa 1456–59), scholar and military commander, defended Smederevo during a Hungarian attack in 1456 Andronikos Palaiologos Kantakouzenos (d. June 3/4, 1453, executed), the last Grand Domestic of the Byzantine Empire Thomas Kantakouzenos (d. July 25, 1463 in Adrianople), diplomat for Đurađ Branković, Despot of Serbia Irene Kantakouzene (d. May 1457), wife of Serbian Despot Đurađ Branković Helena Kantakouzene or Theodora Kantakouzene, Empress of Trebizond A daughter who married George VIII, King of Georgia The Byzantist Donald Nicol, who initially attributed the offspring to Demetrios Kantakouzenos, later reversed his position and stated that it was more likely that Theodore was the actual father. His reason was that, given that George's eldest son was also named Theodore, the new theory would correlate with a common Byzantine practice of naming the eldest son for their grandfather. Similarly, one of Irene's sons was named Todor, possibly also being named after Theodore. Notes References 14th-century Byzantine people Palaiologos dynasty Theodore 1360s births 1410 deaths 15th-century Byzantine people 15th-century Greek people 15th-century deaths from plague (disease) Byzantine diplomats Ambassadors to France Ambassadors of the Byzantine Empire to the Republic of Venice