South Carolina Highway 341 (SC 341) is a state highway that travels through the northeastern part of the U.S. state of South Carolina. It travels diagonally from the southeast to northwest (but signed as north–south) from SC 41 and SC 51 in Johnsonville to U.S. Route 521 Business (US 521 Bus.) and US 601 Bus. in Kershaw. Route description SC 341 begins at the intersection of Georgetown Highway (SC 41/SC 51) and Broadway Street in central Johnsonville. SC 341 heads west along East Broadway Street through the town's business district. At a railroad crossing, the road name changes to West Broadway and continues past additional businesses. After exiting the city limits, the road's name changes to Lake City Highway but passes some other small businesses, houses, and churches. Further from the city, more farmland begins to surround the roadway. At the community of Prospect Corner, the road name becomes Johnsonville Highway but the highway's surroundings is generally the same. Before entering Lake City, SC 341 passes in front of some commercial and industrial warehouses. Upon entering Lake City, SC 341 travels through it on Main Street, first through a residential neighborhood with an elementary school located along it. At Church Street, US 378 Bus. joins SC 341 on a concurrency through the city. Commercial businesses line both sides of the street upon the beginning of the concurrency. In the center of the city, the two routes intersect US 52. After passing Matthews Road west of the downtown area, the road enters another residential neighborhood but then heads into an area with more farmlands. Upon its intersection with US 378, US 378 Bus. ends and SC 341 has a short concurrency with US 378. Continuing northwest from US 378, SC 341 travels along Olanta Highway. At the community of Camp Branch, the highway intersects SC 403 at its southern terminus. SC 341 continues through mostly farmland and afterwards intersects SC 541 at its southern terminus. Shortly thereafter, the road enters the town of Olanta on Hampton Street. Within the town, the road passes in front of many houses, some small businesses, a library, and a school. In the center of town, SC 341 intersects US 301 then begins to curve to the north. The road heads through a mix of farmland and woods north of Olanta where it exits Florence County and enters Sumter County. After an intersection with SC 53,