SC 341 begins to curve to the northwest and has an interchange with Interstate 95 (I-95) at its exit 146. After entering Lee County, SC 341 reaches the community of South Lynchburg where it intersects SC 58 at its western terminus. Soon after, it enters the town of Lynchburg where in the center, it has an intersection with US 76. It continues northwest along Lynchburg Highway through farmland and intersects US 401 about northeast of Elliott. At the settlement of Wisacky, SC 341 reaches the northern terminus of SC 527. Now approaching the city of Bishopville, the highway passes in front of Lee Central High School and has an interchange with I-20 at exit 120. North of the Interstate, it passes the entrance to Lee Correctional Institution. Upon entering the city of Bishopville, it takes the name of East Church Street where it heads through a residential neighborhood then transitions to the business district. In the town center, SC 341 reaches Main Street which carries US 15 through the city. SC 341 and SC 34 (which came into this intersection from West Church Street) form a concurrency with US 15 and head northeast through Bishopville. Outside the city limits, SC 341 breaks off the US 15/SC 34 concurrency and heads north-northwest through farmland and woods on Bethune Highway. The highway enters Kershaw County and soon afterwards heads into the town of Bethune. It travels through the town on Main Street where it intersects US 1 and SC 346. Outside of Bethune, it heads through the pine forests of the Sandhills region. After crossing the Little Lynches River, the road enters Lancaster County. It then enters the town of Kershaw on South Minor Street. At Marion Street, SC 341 turns to the west while SC 157 begins and travels east on Marion Street and SC 157 Truck / SC 341 Truck head north on North Minor Street. The highway heads into the center of town where SC 341 ends at Hampton Street which carries US 521 Bus./US 601 Bus. Marion Street continues west to intersect US 501 and US 601 at Matson Street. Major intersections Kershaw truck route South Carolina Highway 341 Truck (SC 341 Truck) is a truck route for trucks traveling through Kershaw. For its entire length, it is concurrent with SC 157 Truck. Its southern terminus is at the intersection of Marion Street and Minor Street which is