Sarles is a surname. Notable people with the surname include: Bob Sarles (born 1957), American filmmaker Elmore Y. Sarles (1859–1929), American politician Nathalie Sarles (born 1962), French politician Roscoe Sarles (1892–1922), American racecar driver Ruth Sarles Benedict (1906-1996), American journalist William Bowen Sarles (1906–1987), American microbiologist