the first woman president of the American Society for Pharmacology and Experimental Therapeutics (ASPET). She had previously served as secretary-treasurer from 1981 to 1982. She was a member of the American Association for the Advancement of Science. Research Horning published more than 200 scientific articles about biochemistry, pharmacology, and analytical chemistry. Marjorie and Evan Horning were pioneers in the field of analytical biochemistry, in the application of gas chromatography, mass spectrometry, and gas and liquid-mass spectrometric analysis. They developed revolutionary techniques to study the metabolism of drugs and track breakdown products of drugs as they transform and travel throughout the body. Marjorie helped to develop new methods of chromatographic analysis for the study of drug metabolism, including procedures for metabolic profiling and for the study of adrenocortical steroids. Horning investigated the metabolism of drugs and their metabolites in humans, with particular attention to prenatal transmission between a pregnant woman and an embryo or fetus. Her work showed that drugs and their degradation products travel between mother and child and can affect the unborn child. Previous to her research, it had been believed that the placenta acted as a barrier. Her work resulted in changes in medical practice and the prevention of drug-related birth defects. As a result of her work, doctors in the 1980s began to warn women about the risks of taking medications, drinking alcohol, and smoking during pregnancy. Horning also determined that drugs and their metabolites can be passed from mother to child through breast milk. She was a long-term member of the Society of Toxicology and worked with the National Toxicology Program, established in 1978 to identify toxic chemicals. Over 48,000 chemicals were used in the United States at the time, many in food additives, medicinal products, or household products. Awards and honors Frank H. Field and Joe L. Franklin Award in Mass Spectrometry, American Chemical Society, shared with Evan C. Horning, 1990 Tswett Chromatography Medal, International Symposium on Advances in Chromatography 1987 National Honorary Member of Iota Sigma Pi (National Honor Society for Women in Chemistry), 1985 Alumnae Athena award, University of Michigan, 1980 Garvan-Olin Medal, American Chemical Society, 1977 Honorary Doctorate, Goucher College, 1977 Warner Lambert award, American Association of Clinical Chemists, 1976 Personal life While a student at the University of Michigan, she met her husband-to-be, Evan C. Horning (1916-1993), a chemist and teacher. They married on September 26, 1942. Following her retirement in