Peficitinib (trade name Smyraf) is a pharmaceutical drug used for the treatment of rheumatoid arthritis. It belongs to the class of drugs known as Janus kinase inhibitors (JAK inhibitors). Peficitinib was approved for use in Japan in 2019. References Tyrosine kinase inhibitors Adamantanes Pyrrolopyridines Tertiary alcohols Disease-modifying antirheumatic drugs