the Plaintiffs' Executive Committee in the multidistrict litigation related to DePuy Orthopaedics' defective hip implants, which resulted in DePuy's parent company Johnson & Johnson agreeing to a global settlement of $2.5 billion. Since 2012, Seeger served as lead counsel representing retired NFL players in a suit brought against the league for hiding the dangers of concussion injuries. He negotiated a settlement in which the NFL agreed to pay an uncapped amount, estimated to be over $1.5 billion, to address the medical costs of over 20,000 former players who suffered traumatic brain injuries during their professional careers. The settlement was approved by a federal court and upheld by the Third Circuit Court of Appeals in April 2016. As of September, 2022, more than $1 billion in claims have been approved. In 2016, Seeger was appointed to the Plaintiffs’ Steering Committee in the “clean diesel” litigation against German automaker Volkswagen in connection to the company's project to game the emissions tests on their cars. He also served on the settlement committee, which negotiated an approximately $14 billion settlement with VW on behalf of plaintiffs. In 2017, Seeger served as lead negotiator in litigation against agrochemical giant Syngenta regarding Viptera genetically modified corn. The settlement, reached in 2018, totaled $1.5 billion for plaintiffs (primarily U.S. corn farmers). It represents the largest agricultural litigation settlement in U.S. history. In 2019, Seeger was appointed co-lead counsel in multidistrict litigation against 3M. The litigation includes over 250,000 veterans suffering from hearing loss and tinnitus after using earplugs 3M sold to the U.S. Department of Defense, which the suit claims the company knew to be faulty. Since 2019, Seeger has served as interim co-lead counsel for a proposed "negotiation class" of local governments in the pursuit of a nationwide settlement against drug companies in multidistrict opioid litigation. Over 90 percent of litigating local governments participated in global settlements with AmerisourceBergen, Cardinal Health, and McKesson, and Johnson & Johnson totaling $26 billion. In 2021, it was announced that Seeger, along with civil rights attorney Benjamin Crump, would be representing the family of Henrietta Lacks in a lawsuit against several pharmaceutical companies that have profited from the cell line HeLa, which is based on cervical cancer cells taken from Lacks without her knowledge in 1951. The first lawsuit was filed against ThermoFisher. In 2022, Seeger was appointed Co-lead Counsel in an MDL prosecuting claims related to the disintegration or