of the actin cytoskeleton. The following substances interact with UPF0488: 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide, benzo(a)pyrene, methotrexate, and vitamin E. Pathology The expression of the UPF0488 gene increases after treatment with cephaloridine, a semisynthetic derivative of cephalosporin C that inhibits gluconeogenesis in both target (kidney) and non-target (liver) organs. References