aromatizes back to the substituted phenol. The reaction can be used for the synthesis of 2,6-di-tert-butyl-4-methoxyphenol, which is frequently used as an antioxidant. 2,4,6-TTBP is used as stabilizers, free-radical scavengers and antioxidants in technical applications, such as in fuels, hydraulic fluids and lubricating oils, as well as in elastomeric and thermoplastic polymers. Because of its pronounced persistence, its high tendency for bioaccumulation and aquatic toxicity, 2,4,6-TTBP is only of low industrial use and is even forbidden, for example, in Japan. The phenoxy radical of 2,4,6-TTBP is also described as a sterically demanding protecting group in a reagent for the transfer of a nucleophilic dimethylaminomethyl group [(CH3)2-N-CH2-] to form tertiary amines. References Alkylphenols Tert-butyl compounds