and risked her safety. Baldwin-Ragaven et al. note that the medical association "closed ranks in support of colleagues who colluded with the security police in the torture and death of detainees [and] also attempted to silence and discredit those doctors who stood up for human rights and who demanded disciplinary action against their colleagues." After eight years, Ames won the case in 1985 when the South African Supreme Court ruled in her favor. With Ames' help, the case forced the medical regulatory body to reverse their decision. The two doctors who treated Biko were finally disciplined and major medical reforms followed. According to Benatar & Benatar 2012, the case "played an important role in sensitising the medical profession to medical ethical issues in South Africa." Cannabis research Ames studied the effects of cannabis in 1958, publishing her work in The British Journal of Psychiatry as "A clinical and metabolic study of acute intoxication with Cannabis sativa and its role in the model psychoses". Her work is cited extensively throughout the cannabis literature. She opposed the War on Drugs and was a proponent of the therapeutic benefits of cannabis, particularly for people with multiple sclerosis (MS). Ames observed first-hand how cannabis (known as dagga in South Africa) relieved spasm in MS patients and helped paraplegics in the spinal injuries ward of her hospital. She continued to study the effects of cannabis in the 1990s, publishing several articles about cannabis-induced euphoria and the effects of cannabis on the brain. Personal life Ames was married to editorial writer David Castle of the Cape Times and they had four sons. She was 47 years old when her husband died unexpectedly in 1967. After her husband's death, Ames's housekeeper Rosalina helped raise the family. Ames wrote about the experience in her memoir, Mothering in an Apartheid Society (2002). Death Ames struggled with leukemia for some time. Before her death, she told an interviewer, "I shall go on until I drop." She continued to work for UCT as a part-time lecturer at Valkenberg Hospital until six weeks before she died at home in Rondebosch on 11 November 2002. Representing UCT's psychiatry department, Greg McCarthy gave the eulogy at the funeral. Ames was cremated, and according to her wishes, her ashes were combined with hemp seed and dispersed outside of Valkenberg Hospital where her memorial service was held. Legacy South African neurosurgeon Colin Froman referred to Ames