143. In early 2016, the UFC announced that Jędrzejczyk would be one of the coaches, opposite former opponent Cláudia Gadelha on The Ultimate Fighter 23. A rematch between the two took place on July 8, 2016, at The Ultimate Fighter 23 Finale in the MGM Grand Garden Arena in Las Vegas, Nevada. She won the fight via unanimous decision. Both participants were awarded Fight of the Night for their performance. Jędrzejczyk successfully defended her title for the 4th consecutive time by defeating fellow Pole Karolina Kowalkiewicz by unanimous decision on November 12, 2016, at UFC 205 in Madison Square Garden, the first event the promotion had held in the historic arena. Jędrzejczyk faced Jéssica Andrade on May 13, 2017, at UFC 211. She won the fight via unanimous decision, and successfully defended her title for the fifth consecutive time. Jędrzejczyk landed the most significant strikes in UFC championship history (225), had the highest significant strike differential in UFC championship history (142), and broke her previous record for most leg kicks thrown in a single fight (75). For her sixth title defense, Jędrzejczyk faced Rose Namajunas at UFC 217 at Madison Square Garden in New York on November 4, 2017. She lost the bout via KO (punches) in the first round, marking her first professional loss in mixed martial arts competition. Post-championship A title fight rematch between Namajunas and Jędrzejczyk took place on April 7, 2018, at UFC 223. She lost the fight via unanimous decision. Jędrzejczyk faced Tecia Torres on July 28, 2018, at UFC on Fox 30. She won the fight via unanimous decision. Return to Flyweight On September 20, 2018, it was announced that Jędrzejczyk was expected to return to flyweight to face Valentina Shevchenko on December 8, 2018, at UFC 231 for the vacant UFC Women's Flyweight Championship. Due to UFC 230 being in need of a main event, Shevchenko was booked against Sijara Eubanks. After the UFC announced Cormier vs. Lewis on October 9, 2018, UFC confirmed the bout between Shevchenko and Eubanks was canceled and that Jędrzejczyk would again fight for the title against Shevchenko in the co-main event at UFC 231. Jędrzejczyk lost the fight via a unanimous decision. Return to Strawweight Jędrzejczyk faced Michelle Waterson on October 12, 2019, at UFC on ESPN+ 19. Per news reports, Jędrzejczyk had informed the UFC that she might not be able to make the Strawweight limit;