University of Massachusetts Medical School has identified a third gene that is a cause for the disease. Project MinE, a global gene sequencing effort to identify genetic drivers of ALS, received $1 million from the challenge, allowing them to broaden the scope of their research to include new sources in new parts of the world. Having identified the link between the gene, NEK1, and ALS will allow for a new targeted gene for therapy development, as well as focused drug development. Influences Several other challenges have been created and publicised as a result of the publicity of the Ice Bucket Challenge. The My Tree Challenge is an activity launched in Kerala which consists of planting a tree sapling and challenging others to do so. The My Tree Challenge was preceded by a Book List Challenge, started by Facebook users, where users post a list of books that they have read and liked the most. The Rice Bucket Challenge, that started in India in late August 2014 and later spread to other South Asian nations, was also partly a response to the Ice Bucket Challenge's wastefulness of water. The "Pie In The Eye Challenge" challenges the nominated person to receive a pie in the face. One particular occurrence of this, the late 2016 Waitress Pie Challenge, was initiated by the cast of the musical Waitress to raise awareness of breast cancer. The Milk Bucket Challenge in which milk is poured over the nominated person, was organised in August 2015 by English dairy farmers to raise awareness of their financial plight. The Rubble Bucket Challenge, started by Jordanian comedian Mohammed Darwaza, involves dumping a bucket of sand and rocks over one's head. This challenge was further popularized by Palestinian journalist Aymal al Aloul, and aims to increase awareness of Gazans who have lost their homes in the ongoing conflict with Israel. The Love Bucket Challenge, started by Kerala newspaper Malayala Manorama encourages people to fill a bucket with items to donate to orphanages. The Kaapi Challenge uses coffee, and is a challenge done primarily by the Chennai Super Kings to commemorate the 375th anniversary of the city of Chennai. Criticism A number of criticisms arose relating to the campaign, accusing it of being self-congratulatory, focusing primarily on fun rather than donating money to charity, and substituting a trivial activity for more genuine involvement in charitable activities. Writing in The Daily Telegraph, Willard