medical schools around the world to teach histopathology. WormLab (2012): This software tracks the movement of C. elegans, a model organism widely used in research. WormLab is used in research fields such as neurodegeneration, genetics, aging, development, and toxicology. BrainMaker (2015): This software combines serial sections of whole slide images to create full resolution 3D reconstructions of the entire brain (or any organ). BrainMaker is used in cell mapping and cytoarchitectonics. NeuroInfo (2018): This software automatically delineates, identifies and maps brain regions into a common coordinate system, such as the Allen Mouse Brain Reference Atlas and Waxholm Rat Brain Atlas. Researchers use this software for in neurogenomics, transcriptomics, proteomics, and connectomics. MicroDynamix (2020): MicroDynamix is a software that allows researchers to visualize and quantify changes in dendritic spine morphology over a period of time from repeated imaging experiments. MicroFile+ (2020): This software converts microscope image files from most commercial microscope providers into more space efficient, faster-loading JPEG2000 format and helps enrich the metadata and FAIRness of microscopy image data. Vesselucida: This microscope system creates and quantifies vasculature reconstructions. Neuroscientists use this software for research in vasculature diseases. Vesselucida 360 (2018): Vesselucida 360 is used to reconstruct vessels and microvasculature in 3D and obtain data about the length, connections, and complexity of microvessels. Vesselucida 360 is used in research fields such cancer, diabetes, strokes, and other conditions that affect microvasculature. ClearScope (2020): This is a light sheet theta microscope system invented by Dr. Raju Tomer at Columbia University and Dr. Raju Tomer. ClearScope allows researchers to image cleared tissue from large specimens. TissueScope is a whole slide scanner created in collaboration with Huron Digital Pathology. Vesalius is a resonant scanning laser confocal system that allows 2D and 3D imaging for mounted and cleared tissue specimens. References External links https://sbir.nih.gov/statistics/success-stories/mbf-bioscience Biotechnology companies of the United States