The first season of Will & Grace premiered on September 21, 1998, and concluded on May 13, 1999. It consisted of 22 episodes. Cast and characters Main cast Eric McCormack as Will Truman Debra Messing as Grace Adler Megan Mullally as Karen Walker Sean Hayes as Jack McFarland Gary Grubbs as Harlin Polk Recurring cast Shelley Morrison as Rosario Salazar Tom Gallop as Rob Leigh-Allyn Baker as Ellen Special guest stars Rudy Galindo as himself Debbie Reynolds as Bobbi Adler Molly Shannon as Val Bassett Guest stars Beth Lapides as Ione Julian McMahon as Guy in Elevator Wendie Jo Sperber as April Raphael Sbarge as Alex John Slattery as Sam Truman David Sutcliffe as Campbell Miguel Ferrer as Nathan Berry Tom Verica as Danny Episodes References 1 1998 American television seasons 1999 American television seasons Television episodes directed by James Burrows