not very effective when applied with hydroquinone. Skin pore related diseases Since conventional water-soluble vitamin C does not easily penetrate the skin barrier, an amphipathic vitamin C derivative was developed to improve this. However, since lipids such as palmitic acid were chemical modified to ViraminC derivatives in the past, exposure to ultraviolet light generated free fatty acids, raising concerns about lipid peroxidation. It was thought that GO-VC could avoid the problem of lipid peroxidation because GO-VC is amphipathic with octanol instead of lipid. The effect of 0.05% gel of GO-VC was investigated on skin pore related diseases. As a result, it was confirmed that there were no side effects and the number of abnormal pores decreased to 70% or less within 1 to 2 months after application. References Organic acids 3-Hydroxypropenals