the Xuzhou Cancer Hospital, Xuzhou, China. From 1983 to 1990 Waldman was a staff pharmacologist at the Veterans Administration Medical Center, Palo Alto. From 1991 to 1997 he was the medical director of the Clinical Research Unit at Thomas Jefferson University Hospital, where he now is an attending physician. Institutional profiles with details of Waldman's career are visible on the internet. Academic service Waldman has lent academic service by his participation in committees of institutions such as NIH and FDA, in areas like clinical pharmacology training, translational research, and extramural activities. Awards 2010 – Henry Elliott Distinguished Service Award, American Society for Clinical Pharmacology and Therapeutics 2011 – PhRMA Foundation Award in Excellence in Clinical Pharmacology 2012 – Rawls Palmer Progress in Medicine Award, American Society for Clinical Pharmacology and Therapeutics 2015 – Reynold Spector Award in Clinical Pharmacology, American Society for Pharmacology and Experimental Therapeutics 2017 – Elected Fellow, National Academy of Inventors 2020 – Elected Fellow of the American Society for Pharmacology and Experimental Therapeutics Works Research His early career was devoted to characterize the receptor-mediated responses to atrial natriuretic peptide (ANP) in vascular smooth muscle and other cell types, especially its stimulation of guanylyl cyclase to cause the intracellular accumulation of cGMP in the context of vasodilatory phenomena. His subsequent studies on the ANP-like stimulation of guanylyl cyclase by enterotoxins eventually led to new research venues into the study of guanylyl cyclase C and its role in the pathogenesis of colorectal cancer. Recently, Waldman has extensively explored concepts surrounding the role of membrane-bound GUCY2C receptors lining the gastrointestinal tract in relation to the homeostatic regulation of the crypt-surface axis by paracrine hormones uroguanylin and guanylin. His recent research includes the experimental targeting of such receptors in various ways for the treatment of inflammatory bowel disease and colorectal neoplasias, including (under his leadership) a phase-I clinical trial to test a recombinant vaccine against colorectal cancer aimed to immunize against GUCY2C receptors. Publications He was the former chief editor of Clinical Pharmacology & Therapeutics Peer-reviewed journal articles Waldman has published over 300 research articles in peer-reviewed journals. His most cited articles are: SA Waldman, RM Rapoport, F Murad (1984) Atrial natriuretic factor selectively activates particulate guanylate cyclase and elevates cyclic GMP in rat tissues./ Journal of Biological Chemistry 259 (23), 14332–14334 According to Google Scholar, this article has been cited 755 times. R J Winquist, E P Faison, S