cells use to communicate in order to build tissues and organs during the establishment of the vertebrae axis. Recent research by Dale and colleagues discovered new insight into the role of Notch in developmental segmentation which has opened avenues to explore the potential association of mis-regulated Notch signalling in the context of cancer. Further details can be found in their primary publication "CDK 1 and CDK 2 regulate NICD 1 turnover and the periodicity of the segmentation clock". Dale is currently involved in an active project at the Medical Research Council which focuses on Fine-Scale Regulation of Notch Signalling Dynamics, in the Context of the Vertebrate Segmentation Clock. This project began on 14/Aug/2019 and is scheduled to completion on 13/Aug/2022. Awards and recognition Best Postgraduate Supervisor – DUSA Student Led Teaching Awards (2018) British Society of Developmental Biology Secretary (2008–2013) Fellow of the Society of Biology (2012) The Royal Society University Research Fellowship (renewal) (2010) The Royal Society University Research Fellowship (2005) MRC New Investigator Award (2005) Publications Carrieri, F.A., Murray, P.J., Ditsova, D., Ferris, M.A., Davies, P., Dale, J.K (2019) CDK1 and CDK2 regulate NICD1 turnover and periodicity of the segmentation clock. EMBO Reports. 20, 4, p. 1-22 22 p., e46436 doi/10.15252/embr.201846436 Murray, P., Carrieri, F.A., Dale, J.K. (2019) Cell cycle regulation of oscillations yields coupling of growth and from in a computational model of the presomitic mesoderm. Journal of Theoretical Biology. doi/10.1016/j.jtbi.2019.05.006 Mastromina, I., Verrier L, Silva J.C, Storey K.G, and Dale J.K (2018) MYC activity is required for maintenance of the Neuromesodermal Progenitor signalling network and for correct timing of segmentation clock gene oscillations. doi/10.1242/dev.161091 Meakin, P. J., Jalicy, S. M., Montagut , G., Allsop, D. J. P., Cavellini, D. L.,Irvine, S. W., McGinley, C., Liddell, M. K., McNeilly, A. D., Parmionova, K., Liu, Y., Bailey, C. S. L., Dale, J. K., Heisler, L. K., McCrimmon, R. J., Ashford, M. L. J. (2018) Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice. Scientific Reports 8, Article number: 55 doi/10.1038/s41598-017-18388-6 Bailey, C. S. L., Bone, R. A., Murray, P. J., Dale, J. K (2017) Temporal ordering of dynamic expression data from detailed spatial expression maps. doi/10.3791/55127 Dale, K., Martí, E (2017) Introduction to the special section: Spinal Cord a model to understand CNS development and regeneration. doi/10.1016/j.ydbio.2017.10.005 Carrieri FA and Dale JK (2016) Turn It Down a Notch. Front. Cell Dev. Biol. 4:151. doi/10.3389/fcell.2016.00151 Ellis, P.S., Burbridge,