1-Ethynylcyclohexanol (ECX) is an alkynyl alcohol derivative which is both a synthetic precursor to, and an active metabolite of the tranquilizer ethinamate, and has similar sedative, anticonvulsant and muscle relaxant effects. It has been sold as a designer drug, first being identified in the UK in March 2012. Preparation 1-Ethynylcyclohexanol can be prepared from cyclohexanone by the reacting it with sodium acetylide in liquid ammonia, followed by an acidic work-up. See also 1,6-Dioxecane-2,7-dione 2-Methyl-2-butanol 2-Methyl-2-pentanol 3-Methyl-3-pentanol Clocental Ethchlorvynol Methylpentynol Prenderol References Alcohols Muscle relaxants Ethynyl compounds