number of other advances in algesiometry or dolorimetry (i.e., pain testing in animals) including the development of an animal model of vulvodynia. Demonstration of empathy in mice Although a handful of controversial papers from the 1950s and 1960s had suggested that non-primate mammals might be capable of altruism, Mogil's group was the first to provide modern evidence that mice were capable of emotional contagion of pain, a form of empathy. They showed that mice display more pain behavior if they are tested in close proximity to other mice also in pain, but only if the two mice are familiar with each other. This finding, which was also widely covered in the press, launched a renaissance of new research into the topic of rodent social abilities. Mogil's lab subsequently showed that familiar (but not stranger) humans also demonstrate highly similar emotional contagion of pain, and that reduction of stress via metyrapone treatment or a shared social experience (playing the videogame Rock Band together) can elicit empathy in strangers. This study was covered in the popular press, including an episode of the TED Radio Hour. Discovery of pain genes Using both quantitative trait locus mapping and genetic association study (including GWAS) techniques, Mogil's laboratory has provided evidence for the involvement of over 25 genes with pain and analgesia. The most notable of these was the demonstration in 2003 that the MC1R gene, most well known for its mutations causing red hair, is associated with Κ-opioid analgesia in women but not men. This finding was featured in the popular press. Discovery of factors affecting experiments Mogil and colleagues revealed a number of previously unidentified factors affecting the conclusions drawn from biomedical experiments. In 1996, they demonstrated that the newly discovered orphan opioid peptide, orphanin FQ/nociception, did not produce hyperalgesia as originally reported, but rather was reversing the stress-induced analgesia resulting from the intracerebroventricular injection through which it was administered. In 1999, they showed that different inbred strains of mice displayed very different pain sensitivity. Chief among these methodological confounds was the observation that mice display a stress response to the presence of nearby males of a number of mammalian species, including human male experimenters, calling into question the results of thousands of studies in the animal literature when the sex of the experimenter was not controlled, an animal equivalent to the "sweaty t-shirt study" in humans. This finding led to torrent of media