Securinine is an alkaloid found in Securinega suffruticosa and Phyllanthus niruri. Pharmacology Securinine has pro-convulsant effects and it has a strong spastic effect, similar to the actions of strychnine. Securinine is a GABA-A antagonist. See also Norsecurinine Phenazine References Tetracyclic compounds Nitrogen heterocycles Lactones Alkaloids Furanones Cyclohexenes Withdrawn drugs