located in eastern and southwestern Mississippi, taking in Meridian, Starkville, Pearl, Natchez, and most of the wealthier portions of Jackson, including the portion of the city located in Rankin County. The incumbent is Republican Michael Guest, who was elected with 64.7% of the vote in 2020.Guest managed to flip Kemper County which gave Joe Biden 61.02% of the vote in the 2020 presidential election Republican primary Candidates Nominee Michael Guest, incumbent U.S. Representative Eliminated in runoff Michael Cassidy, U.S. Navy veteran Eliminated in primary Thomas Griffin, businessman Results Democratic primary Candidates Nominee Shuwaski Young, political organizer Withdrawn Rahim Talley, businessman, Iraq war veteran and progressive activist General election Predictions Results District 4 The 4th district encompasses the Mississippi Gulf Coast, including Gulfport, Biloxi, Hattiesburg, Bay St. Louis, Laurel, and Pascagoula. The incumbent is Republican Steven Palazzo, who was re-elected unopposed in 2020. Republican primary Candidates Nominee Mike Ezell, Jackson County sheriff and former Ocean Springs police chief Eliminated in runoff Steven Palazzo, incumbent U.S. Representative Eliminated in primary Carl Boyanton, produce store owner and candidate for this district in 2020 Raymond Brooks, police officer Kidron Peterson Clay Wagner, banker Brice Wiggins, state senator Endorsements Polling Results Democratic primary Candidates Nominee Johnny DuPree, former Mayor of Hattiesburg; nominee for Governor of Mississippi in 2011 and Secretary of State of Mississippi in 2019 Eliminated in primary David Sellers, pastor Endorsements Results Libertarian primary Candidates Declared Alden Patrick Johnson, firefighter Results Independents Candidates Declared Graham Hudson General election Predictions Endorsements Results Notes Partisan clients References External links Official campaign websites for 1st district candidates Mark Strauss (R) for Congress Trent Kelly (R) for Congress Official campaign websites for 2nd district candidates Ron Eller (R) for Congress Brian Flowers (R) for Congress Jerry Kerner (D) for Congress Bennie Thompson (D) for Congress Official campaign websites for 3rd district candidates Michael Cassidy (R) for Congress Michael Guest (R) for Congress Rahim Talley (D) for Congress Shuwaski Young (D) for Congress Official campaign websites for 4th district candidates Carl Boyanton (R) for Congress Raymond Brooks (R) for Congress Johnny DuPree (D) for Congress Mike Ezell (R) for Congress Alden Patrick Johnson (L) for Congress Steven Palazzo (R) for Congress David Sellers (D) for Congress Clay Wagner (R) for Congress Brice Wiggins (R) for Congress 2022 Mississippi United States House of Representatives