linebackers Derrick Morgan and Brian Orakpo, to begin the regular season. On October 11, 2015, Williamson recorded nine combined tackles and made his first sack of the season on Tyrod Taylor during a 14–13 loss to the Buffalo Bills. He left the game after sustaining a hamstring injury in the fourth quarter and was inactive for the Titans' Week 6 loss to the Miami Dolphins. In Week 7, Williamson recorded five combined tackles, a pass deflection, and made his first career interception off a pass attempt by Matt Ryan in the Titans' 10–7 loss to the Atlanta Falcons. After five consecutive losses head coach Ken Whisenhunt was fired and was replaced with offensive coordinator Mike Mularkey as interim head coach. On November 15, 2015, Williamson collected a season-high 14 combined tackles (seven solo) and was credited with half a sack on Cam Newton during a 27–10 loss to the Carolina Panthers. Williamson celebrated his sack on Cam Newton with teammate David Bass by performing a rendition of the dance from rapper Drake's music video "Hotline Bling". He finished with a total of 102 combined tackles (63 solo), 3.5 sacks, a pass deflection, and an interception in 15 games and 15 starts. 2016 Head coach Mike Mularkey retained Dick LeBeau and named him the sole coordinator of the defense after Ray Horton opted to accept the defensive coordinator position with the Cleveland Browns. LeBeau retained Willamson and Woodyard as the starting inside linebackers to begin the regular season after Zach Brown departed for the Buffalo Bills during free agency. In Week 3, Williamson recorded nine combined tackles, broke up a pass, and intercepted Derek Carr during a 17–10 loss to the Oakland Raiders. The following week, he recorded a season-high 12 combined tackles in the Titans' 27–20 loss at the Houston Texans. On December 11, 2016, Williamson made three combined tackles and forced the first fumble of his career as Tennessee defeated the Denver Broncos 13–10. Williamson finished the season with a career-high 104 combined tackles (73 solo), two sacks, a pass deflection, and an interception in 16 games and 16 starts. The Tennessee Titans saw significant improvement under their new head coach, going from 3–13 to 9-7 and finishing second in the AFC South, but did not qualify for a playoff berth. Williamson received an overall grade of 76.5 from Pro Football Focus, ranking him 41st among all qualified linebackers