Keeler has been interviewed by various media outlets about the topics of racial stereotypes. Her activism also extends to issues of abortion, traditional Native values and Indigenous rights, and issues of Indigenous sovereignty. In 2021 Keeler began investigating the issue of settler self-Indigenization in academia. Speaking with Voice of America, she said, "As a reporter, I'd be working on a story about someone, only to find out that person wasn't actually Native." Working with other Natives in tribal enrollment departments, genealogists and historians, they began following up on the names many had been hearing for years in tribal circles were not actually Native, asking about current community connections as well as researching family histories "as far back as the 1600s" to see if they had any ancestors who were Native or had ever lived in a tribal community. This research resulted in the Alleged Pretendians List, of about 200 public figures in academia and entertainment, which Keeler self-published as a Google spreadsheet in 2021. Some people have criticized her for "conducting a witch hunt". Johnnie Jae, and others, have questioned the research and motives of the list, as well as what they say is anti-Black bias. Native leaders interviewed by VOA report Keeler has strong support in Native circles. Keeler has stressed that the list does not include private citizens who are "merely wannabes", but only those public figures who are monetizing and profiting from their claims to tribal identity and who claim to speak for Native American tribes. In an interview with APTN, Keeler said she and her team decided to compile the Alleged Pretendians list (stressing the "Alleged") to show how pervasive the problem is - that numerous non-Natives are profiting off fraud, are in positions of authority in academia, film and television and that non-Native individuals with no connections to the communities they claim are "positioning themselves as our spokespeople on National and International issues." She says the list is the product of decades of Native peoples' efforts at accountability. Author Keeler is the author of Standoff: Standing Rock, the Bundy Movement, and the American Story of Sacred Lands. Praised by Ojibway author Louise Erdrich: "Rigorous analysis and personal storytelling invigorate Jacqueline Keeler's examination of Indigenous vs. colonial land tenure. Standoff recounts the historic legacy of treaty rights and sacred space underpinning Standing Rock's case against the Dakota Access Pipeline, and contrasts this legacy with the white