Scotiabank Place (18,429) || 5–8–1 |- align="center" bgcolor="#ccffcc" | 15 || 15 || Boston Bruins || 4–2 || Miller (6–6–1) || First Niagara Center (19,070) || 6–8–1 |- align="center" bgcolor="#ffbbbb" | 16 || 17 || Pittsburgh Penguins || 3–4 || Miller (6–7–1) || First Niagara Center (19,070) || 6–9–1 |- align="center" bgcolor="#ffbbbb" | 17 || 19 || Winnipeg Jets || 1–2 || Miller (6–8–1) || First Niagara Center (19,070) || 6–10–1 |- align="center" bgcolor="#ffbbbb" | 18 || 21 || @Toronto Maple Leafs || 1–3 || Miller (6–9–1) || Air Canada Centre (19,473) || 6–11–1 |- align="center" bgcolor="#ffbbbb" | 19 || 23 || New York Islanders || 0–4 || Miller (6–10–1) || First Niagara Center (19,070) || 6–12–1 |- align="center" bgcolor="#ccffcc" | 20 || 26 || @Tampa Bay Lightning || 2–1 || Miller (7–10–1) || Tampa Bay Times Forum (19,204) || 7–12–1 |- align="center" bgcolor="#ccffcc" | 21 || 28 || @Florida Panthers || 4–3 (SO) || Miller (8–10–1) || BB&T Center (15,672) || 8–12–1 |- |- align="center" bgcolor="#ccffcc" | 22 || 2 || New Jersey Devils || 4–3 (SO) || Miller (9–10–1) || First Niagara Center (19,070) || 9–12–1 |- align="center" bgcolor="#ffffcc" | 23 || 3 || @New York Rangers || 2–3 (SO) || Miller (9–10–2) || Madison Square Garden (17,200) || 9–12–2 |- align="center" bgcolor="#ffbbbb" | 24 || 5 || @Carolina Hurricanes || 3–4 || Miller (9–11–2) || PNC Arena (15,277) || 9–13–2 |- align="center" bgcolor="#ffffcc" | 25 || 7 || @New Jersey Devils || 2–3 (SO) || Miller (9–11–3) || Prudential Center (17,625) || 9–13–3 |- align="center" bgcolor="#ffbbbb" | 26 || 10 || @Philadelphia Flyers || 2–3 || Miller (9–12–3) || Wells Fargo Center (19,687) || 9–14–3 |- align="center" bgcolor="#ccffcc" | 27 || 12 || New York Rangers || 3–1 || Enroth (1–2–0) || First Niagara Center (19,070) || 10–14–3 |- align="center" bgcolor="#ffffcc" | 28 || 16 || Ottawa Senators || 3–4 (OT)|| Miller (9–12–4) || First Niagara Center (19,070) || 10–14–4 |- align="center" bgcolor="#ffbbbb" | 29 || 17 || @Washington Capitals || 3–5 || Miller (9–13–4) || Verizon Center (18,506) || 10–15–4 |- align="center" bgcolor="#ccffcc" | 30 || 19 || @Montreal Canadiens || 3–2 (OT) || Enroth (2–2–0) || Bell Centre (21,273) || 11–15–4 |- align="center" bgcolor="#ccffcc" | 31 || 21 || Toronto Maple Leafs || 5–4 (SO) || Miller (10–13–4) || First Niagara Center (19,070) || 12–15–4 |- align="center" bgcolor="#ccffcc" | 32 || 23 || @Montreal Canadiens