well as a range of clinically important pathogens, such as Legionella, Pseudomonas, nontuberculous mycobacteria (NTM), Acinetobacter, Elizabethkingia, and Naegleria. Early adopters of HACCP for building water systems include leading healthcare institutions, notably the Mayo Clinic in Rochester, Minnesota. ISO 22000 Food Safety Management System ISO 22000 is a standard designed to help augment HACCP on issues related to food safety. Although several companies, especially big ones, have either implemented or are on the point of implementing ISO 22000, there are many others which are hesitant to do so. The main reason behind that is the lack of information and the fear that the new standard is too demanding in terms of bureaucratic work. ISO 22000 references the Codex Alimentarius General Principles of Food Hygiene, CXC 1-1969 which includes HACCP principles and 12 HACCP application steps. This is explained in a joint publication from ISO and United Nations Industrial Development Organization (UNIDO) which provides guidance to assist all organizations (including small and medium-sized) that recognize the potential benefits of implementing a Food Safety Management System. See also Failure mode and effects analysis Failure mode, effects, and criticality analysis Fault tree analysis Food safety Design Review Based on Failure Mode Fast food restaurant ISO 22000 Hazard analysis Hazard analysis and risk-based preventive controls Hazop Hygiene Sanitation Sanitation Standard Operating Procedures Codex Alimentarius Total quality management References Food safety Food technology Quality management Hazard analysis United States Department of Agriculture Drinking water