featured in Spider-Man: Across the Spider-Verse (2023). He will be portrayed as a member of the Spider-Forces led by Miguel O' Hara / Spider-Man 2099. Video games Doctor Octopus has appeared as a boss and occasional playable character in multiple Spider-Man and non-Spider-Man-related video games. The Superior Spider-Man has also been featured as a playable character in several games. Spider-Man games Doctor Octopus appeared in Questprobe featuring Spider-Man. Doctor Octopus appeared as a boss in The Amazing Spider-Man for the Game Boy. Doctor Octopus appeared in Spider-Man: The Video Game. Doctor Octopus appeared as the final boss in Spider-Man: Return of the Sinister Six. Doctor Octopus appeared as the first boss in The Amazing Spider-Man vs. The Kingpin. Doctor Octopus appeared as the first boss in the 1995 Spider-Man game. Doctor Octopus appeared as a boss in Spider-Man: Lethal Foes. Doctor Octopus appeared as a boss in the 2000 Spider-Man video game, voiced again by Efrem Zimbalist, Jr. While pretending to have reformed, he works with Carnage to turn everyone in New York into symbiotes, but they are both defeated by Spider-Man. Following this, the Carnage symbiote bonds with Doctor Octopus, turning him into Monster Ock (voiced by Marcus Shirock). After Monster Ock is defeated, Doctor Octopus is returned to normal and promptly arrested. Doctor Octopus appeared as the final boss in Spider-Man 2: The Sinister Six. Doctor Octopus makes a cameo appearance at the end of Spider-Man 2: Enter Electro. Doctor Octopus appears as the final boss in the Spider-Man 2 film tie-in game, with Alfred Molina reprising his role from the aforementioned film. Doctor Octopus appears as a boss playable and character in Spider-Man: Friend or Foe, voiced by Joe Alaskey. He and several supervillains attack Spider-Man until they are all attacked by P.H.A.N.T.O.M.s under Mysterio's command. Doc Ock is captured along with the other villains, placed under mind control, and sent to Tokyo to retrieve a meteor shard located there. After Spider-Man defeats Doctor Octopus and destroys the mind-control device, the latter joins forces with the former to exact revenge on Mysterio. Doctor Octopus appears in Spider-Man: Edge of Time, voiced by Dave B. Mitchell. When Alchemax scientist Walker Sloan travels back from the year 2099 to establish his company in the 1970s, Otto Octavius became a scientist employed by the company and never turned to crime, though he still uses his tentacles as research tools. His