and developments In 1993, The University of Texas M.D. Anderson Cancer Center began a $248.6-million expansion project which constructed an inpatient pavilion with 512 beds, two research buildings, an outpatient clinic building, a faculty office building, and a patient-family hotel. From 2005 to present, the George and Cynthia Mitchell Basic Sciences Research Building, the Ambulatory Clinical Building, the Cancer Prevention Center and a new research building on the South Campus opened. The Proton Therapy Center, the largest facility in the United States where proton therapy is used to treat cancer, opened in July 2006. In 2001, the Texas Medical Center was devastated by Tropical Storm Allison, which flooded basements and the first floors with 18 inches of water. This resulted in retrofitting of storm doors and barriers to prevent future flooding. The Memorial Hermann Healthcare System constructed the six-floor, Memorial Hermann Heart & Vascular Institute. Also recently completed around 2006 was the 30-story Memorial Hermann Medical Plaza, which is now the largest medical office building in the Texas Medical Center. At night, it became recognizable by its unique rainbow lantern. The construction was part of the system's citywide "Century Project" initiative. In 2005, Baylor College of Medicine opened the Baylor Clinic. The Texas Children's Hospital announced the largest investment and program expansion ever by a single pediatric organization. The $1.5 billion, four-year initiative was targeted for completion in 2010 and focused on research and accessibility. Major projects included the development of the neurological research institute ($215 million), the formation of a maternity center ($575 million), and the expansion of existing research facilities ($120 million). Texas Children's was undertaking the development of one of the largest pediatric hospitals in a suburban setting ($220 million). The remainder of the expenditures were earmarked for new equipment and information systems. In 2010, the University of Texas Medical Branch at Galveston, including the John Sealy Hospital, became the 49th member of the Texas Medical Center and the first member-institution located outside the City of Houston. Texas Medical Center–West Campus, serving residents of greater west Houston and adjacent areas, opened in January, 2011. Representing an initial investment of more than half a billion dollars, and almost 1.2 million square feet of healthcare development, the first two facilities to open in the new campus were the Texas Children’s Hospital and The Houston Methodist West Hospital. Texas Children’s West Campus is among the nation’s largest suburban pediatric hospitals.