again defeated by Spider-Man, who confronts Doctor Octopus unmasked, after two of Peter's students distract Octavius. He is then sent to Baron Zemo's supervillain detention facility (as seen in Thunderbolts #104 and Iron Man (vol. 4) #14). Later, Spider-Man contacts Octavius to see if he can help with Aunt May's condition. Dying When Doctor Octopus learns that he is dying due to the years of punishment his body took in his villainous career, facing superhuman foes when he is fundamentally human once getting past the tentacles, he becomes increasingly despondent and brazen in his final plans. Intending to leave a lasting legacy, he attempts to exert control over New York City by using his newly minted Octobots, but while he consciously intends to help, his subconscious drives him to turn the city's resources against Spider-Man, and he also targets May Parker aggressively (deeming her guilty of being due to marry J. Jonah Jameson's father J. Jonah Jameson, Sr.), subtly disrupting the planned marriage. Spider-Man is eventually able to take control of Octavius's planned network, forcing Octavius to flee while vowing revenge. In his desperate attempts to prolong his life, Octavius reforms the Sinister Six, wishing to acquire Menace's unborn son, hoping to synthesize a pure strain of the Goblin Serum, only to be thwarted again by the efforts of Spider-Man and the guilty conscience of the Lizard, reigniting his bitterness towards his foe, but gaining a grudging acknowledgment of his abilities. Octavius and Spider-Man keep crossing their ways during the following months, with the Avengers fighting a new iteration of the Sinister Six, Doctor Octopus sending a remote Octobot in John Jameson's shuttle, and Octavius contacting Iron Man to force him to find a cure for his degenerative condition. However, when Iron Man genuinely offers to have the brightest minds in the Marvel Universe find a viable cure, Octavius smugly refuses, in favor of witnessing Stark admit that he cannot do it and beg for mercy to disarm a device that Octavius had claimed was a bomb, basking in this "proof" of his (supposedly) superior intellect. His attempts to prolong his life, however, do not hinder a more vast and sinister plan, in which he has the Sinister Six fighting the Avengers Academy for a piece of Hank Pym's technology, the Future Foundation for a piece of Reed Richard's technology, and the Intelligencia for the Zero Cannon, a powerful antigravity