Norman Osborn uses a sample of Anti-Venom's DNA from Mac Gargan and creates a poisonous counter to its healing powers by combining the sample with the immune system of Freak. Mac Gargan is injected with the "cure" and is given a new Scorpion battlesuit, which contains the venom, until the symbiote can recover. Anti-Venom tracks down Gargan at Oscorp. After a grueling battle "Ven-orpion" injects the toxin into Anti-Venom and seemly kills the suit. He then attempts to kill Brock but the symbiote tries holding him back, still feeling love for its former host. The symbiote gains its strength and breaks though the Scorpion suit. Gargan gives up but promises that he will get past this problem and will someday finish Brock. Secret Invasion Gargan was seen being thrown from Thunderbolt Mountain by Captain Marvel. Gargan was later seen with the other Thunderbolts in Washington. The Skrulls attempt to trick him into killing normal humans in order to find out which of them are Skrulls. Osborn attempted to prevent the symbiote from killing anyone by threatening to kill Mac Gargan and promising to help satisfy his "urges" later, only for Gargan to reveal that the threat he appeared to pose to civilians was a ruse in order to draw out a disguised Skrull. Venom played a huge part in fighting the Skrulls. He was seen slashing and eating the Skrulls all at once. He soon joins the Thunderbolts and the remaining heroes for the final battle against the Skrulls. During the battle, he was a force to be reckoned with. Venom, along with most of the Thunderbolts team, attempts to kill partner Songbird on the orders of Osborn. Facing Venom, Songbird was defeated and almost eaten by Venom, but escaped with help from the Swordsman. Dark Reign Norman Osborn forms the Dark Avengers, providing new identities to some of his former Thunderbolts. After feeding a Skrull to a hungry Venom that has become more bestial than human, Osborn gives him a medication that resets the symbiote to the size it was when it possessed Spider-Man originally. Gargan can transform into his larger Venom form at will. Norman introduces Gargan and the symbiote as "Spider-Man" of the Dark Avengers. During their first mission against Morgana le Fay, Morgana transforms "Venom-Spidey" into a giant, demonic monster who then tries to eat Ares. Venom later coughs up Ares; however, Morgana's magic continues to