1806, Zebulon Pike passed through Kansas and labeled it "the Great American Desert" on his maps. This view of Kansas would help form U.S. policy for the next 40 years, prompting the government to set it aside as land reserved for Native American resettlement. From June 4, 1812 until August 10, 1821 the area that would become Kansas Territory 33 years later was part of the Missouri Territory. When Missouri was granted statehood in 1821 the area became unorganized territory and contained few if any permanent white settlers, except Fort Leavenworth. The Fort was established in 1827 by Henry Leavenworth with the 3rd U.S Infantry from St. Louis, Missouri; it is the first permanent European settlement in Kansas. The fort was established as the westernmost outpost of the American military to protect trade along the Santa Fe Trail from Native Americans. The trade came from the East, by land using the Boone's Lick Road, or by water via the Missouri River. This area, called the Boonslick, was located due east in west-central Missouri and was settled by Upland Southerners from Virginia, Kentucky, and Tennessee as early as 1812. Its slave-owning population would contrast with settlers from New England who would eventually arrive in the 1850s. A section of the Santa Fe Trail through Kansas was used by emigrants on the Oregon Trail, which opened in 1841. The westward trails served as vital commercial and military highways until the railroad took over this role in the 1860s. To travelers en route to Utah, California, or Oregon, Kansas was an essential way stop and outfitting location. Wagon Bed Spring (also Lower Spring or Lower Cimarron Spring) was an important watering spot on the Cimarron Cutoff of the Santa Fe Trail. Other important locations along the trail were the Point of Rocks and Pawnee Rock. 1820s–1840s: Indian territory Beginning in the 1820s, the area that would become Kansas was set aside as Indian Territory by the U.S. government, and was closed to settlement by whites. The government resettled to Indian Territory (now part of Oklahoma) those Native American tribes based in eastern Kansas, principally the Kansa and Osage, opening land to move eastern tribes into the area. By treaty dated June 3, 1825, 20 million acres (81000 km2) of land was ceded by the Kansa Nation to the United States, and the Kansa tribe was limited to a specific reservation in northeast Kansas.