Odaihara. In 1547, he took Shika Castle. In 1548, Shingen defeated Ogasawara Nagatoki in the Battle of Shiojiritoge and then took Fukashi Castle in 1550. However, the warlord was checked at Uedahara by Murakami Yoshikiyo, losing two of his generals in a heated battle which Murakami won. Shingen managed to avenge this loss and the Murakami clan was eventually defeated in the sieges of Toishi. Murakami fled the region, eventually coming to plead for help from the Province of Echigo. In 1553, he captured Katsurao, Wada, Takashima and Fukuda castles. In 1554 he took Fukushima, Kannomine, Matsuo and Yoshioka castles. Conflict with Uesugi After conquering Shinano Province, Shingen faced another rival, Uesugi Kenshin of Echigo Province. The feud between them became legendary, and they faced each other on the battlefield five times in the Battles of Kawanakajima. These battles were generally confined to controlled skirmishes, neither daimyō willing to devote himself entirely to a single all-out attempt. The conflict between the two that had the fiercest fighting, and might have decided victory or defeat for one side or the other, was the fourth battle, during which the famous tale arose of Uesugi Kenshin's forces clearing a path through the Takeda troops and Kenshin engaging Shingen in single combat. The tale has Kenshin attacking Shingen with his sword while Shingen defends with his iron war fan or tessen. Both lords lost many men in this fight, and Shingen in particular lost two of his main generals, Yamamoto Kansuke and his younger brother Takeda Nobushige. After the fourth battle of Kawanakajima, the Takeda clan suffered two internal setbacks. Shingen uncovered two plots on his life, the first from his cousin Suwa Shigemasa (whom he ordered to commit seppuku), and the second, a few years later, from his own son Takeda Yoshinobu (武田義信). His son was confined to the Toko-ji temple, where he died two years later; it is not known whether his death was natural or ordered by his father. After this incident, Shingen designated his fourth son, Takeda Katsuyori (武田勝頼), as the acting leader of the clan after himself until Katsuyori's son came of age. Kōzuke campaign In 1563, Shingen allied with Hōjō Ujiyasu, and helped Ujiyasu capture Matsuyama Castle in Musashi Province. In 1565, Shingen then took Kuragano Castle and Minowa Castle in Kōzuke province. In 1571, Uesugi Kenshin had advanced to the province of Kozuke and attacked the satellite