In medicine, the words were occasionally used to describe a disease known to medieval physicians as a "hidden cancer" or cancer absconditus; the more the swellings associated with these cancers were handled, the worse they became. Botany The touch-me-not balsam is known by the binominal name Impatiens noli-tangere; its seed pods can explode when touched, dispersing the seeds widely. Hibiscus noli-tangere has sharp glass-like needles that detach from its leaves when touched. In culture and literature Like other significant scenes in the Gospels, this expression was used repeatedly in Christian culture, specifically literature. Following 14th century poet Petrarch, 16th-century poet Sir Thomas Wyatt, in his lyric poem "Whoso list to hunt", says the speaker is hunting a hind, who stands for the elusive lover. The doe wears an inscribed collar: "There is written, her fair neck round about: / Noli me tangere, for Caesar's I am". Pliny the Elder had an account about deer of "Caesar", which lived 300 years and wore collars with that inscription. In another source, Solinus (fl. 3rd century AD) wrote that after Alexander the Great collared deer, they survived 100 years. He did not mention any inscription on the collars. D. H. Lawrence refers to the phrase on several occasions, most notably in his poem "Noli Me Tangere" satirizing cerebralism. Filipino poet and activist José Rizal used this phrase as the title of his novel, Noli Me Tángere (1887), criticizing the Spanish colonization of the Philippines. He writes that ophthalmologists use this phrase in reference to a cancer of the eyelids. It symbolized the people's blindness to the ruling government, which Rizal deemed a social cancer that people were too afraid to touch. The thirteen-hour version of the experimental film Out 1 (1971) is sometimes subtitled Noli Me Tangere, as an ironic reference to it being the uncut version favoured by the director Jacques Rivette (as opposed to the edited version, Out 1: Spectre, which is four hours long). In United States history and military Historically, the phrase was used by Revolutionary-Era Americans in reference to the Gadsden flag—with its derivation "don't tread on me"—and other representations dating to the American Revolutionary War. In the United States military, the phrase is the motto of the US Army's oldest infantry regiment, the 3rd U.S. Infantry Regiment (The Old Guard), located at Fort Myer, Virginia. The snake symbol can be found in the coat of arms of