5–4 || Romero (15–10) || Bard (2–8) || Francisco (15) || 37,087 || 75–74 || 15½ |- style="text-align:center; background:#cfc;" | 150 || September 16 || Yankees || 5–4 || Janssen (5–0) || Logan (5–3) || || 29,323 || 76–74 || 14½ |- style="text-align:center; background:#fbb;" | 151 || September 17 || Yankees || 7–6 || Laffey (3–2) || Villaneuva (6–4) || Rivera (42) || 39,288 || 76–75 || 15½ |- style="text-align:center; background:#cfc;" | 152 || September 18 || Yankees || 3–0 || Morrow (10–11) || García (11–8) || Francisco (16) || 34,657 || 77–75 || 14½ |- style="text-align:center; background:#cfc;" | 153 || September 19 || Angels || 3–2 (10) || Janssen (6–0) || Downs (6–3) || || 11,178 || 78–75 || 14½ |- style="text-align:center; background:#fbb;" | 154 || September 20 || Angels || 10–6 || Piñiero (7–7) || Cecil (4–10) || Downs (1) || 13,514 || 78–76 || 15½ |- style="text-align:center; background:#fbb;" | 155 || September 21 || Angels || 7–2 || Haren (16–9)|| McGowan (0–1) || || 14,784 || 78–77 || 17 |- style="text-align:center; background:#cfc;" | 156 || September 22 || Angels || 4–3 (12) || Camp (5–3) || Richards (0–2) || || 22,769 || 79–77 || 16 |- style="text-align:center; background:#cfc;" | 157 || September 23 || @ Rays || 5–1 || Morrow (11–11) || Price (12–13) || || 18,093 || 80–77 || 15½ |- style="text-align:center; background:#fbb;" | 158 || September 24 || @ Rays || 6–2 || Torres (1–1) || Romero (15–11) || || 27,773 || 80–78 || 16½ |- style="text-align:center; background:#fbb;" | 159 || September 25 || @ Rays || 5–2 || Davis (11–10) || Cecil (4–11) || Peralta (6) || 21,008 || 80–79 || 17 |- style="text-align:center; background:#fbb;" | 160 || September 26 || @ White Sox || 4–3 || Axelrod (1–0) || McGowan (0–2) || Santos (30) || 21,320 || 80–80 || 17 |- style="text-align:center; background:#fbb;" | 161 || September 27 || @ White Sox || 2–1 || Buehrle (13–9) || Álvarez (1–3) || Sale (3) || 23,934 || 80–81 || 17 |- style="text-align:center; background:#cfc;" | 162 || September 28 || @ White Sox || 3–2 || Camp (6–3) || Sale (2–2) || Francisco (17) || 20,524 || 81–81 || 16 |- Honours and awards All-Star Game José Bautista, 2nd selection Ricky Romero, 1st selection Home Run Derby José Bautista, 1st selection Player of the Week Ricky Romero – August 1–7 Player of the Month José