|| Nationals || 1–0 || Gee (3–0) || Hernández (3–6) || Rodríguez (14) || 26,835|| 21–22 || Boxscore |- align="center" bgcolor="bbffbb" | 44 || May 20 || @ Yankees || 2–1 || Dickey (2–5) || García (2–4) || Rodríguez (15) || 47,874 || 22–22 || Boxscore |- align="center" bgcolor="ffbbbb" | 45 || May 21 || @ Yankees || 3–7 || Burnett (5–3) || Capuano (3–5) || || 48,286 || 22–23 || Boxscore |- align="center" bgcolor="ffbbbb" | 46 || May 22 || @ Yankees || 3–9 || Ayala (1–0) || Pelfrey (3–4) || || 48,293 || 22–24 || Boxscore |- align="center" bgcolor="ffbbbb" | 47 || May 24 || @ Cubs || 1–11 || Dempster (3–4) || Niese (3–5) || || 35,707 || 22–25 || Boxscore |- align="center" bgcolor="bbffbb" | 48 || May 25 || @ Cubs || 7–4 (7) || Gee (4–0) || Coleman (2–4) || || 36,666 || 23–25 || Boxscore |- align="center" bgcolor="ffbbbb" | 49 || May 26 || @ Cubs ||3–9||Zambrano (5–2)||Beato (1–1)|| ||33,378 ||23–26 ||Boxscore |- align="center" bgcolor="ffbbbb" | 50 || May 27 || Phillies ||4–6|| Bastardo (3–0)|| Rodríguez (1–1) || Madson (10)|| 33,882 ||23–27||Boxscore |- align="center" bgcolor="ffbbbb" | 51 || May 28 || Phillies ||2–5||Hamels (7–2) ||O'Connor (0–1) ||Madson (11)|| 29,337 ||23–28||Boxscore |- align="center" bgcolor="bbffbb" | 52 || May 29 || Phillies ||9–5||Niese (4–5) ||Worley (2–1) || || 30,791 ||24–28 ||Boxscore |- align="center" bgcolor="bbffbb" | 53 || May 30 || Pirates ||7–3|| Gee (5–0)|| |McCutchen (1–1) || ||24,490||25–28||Boxscore |- align="center" bgcolor="ffbbbb" | 54 || May 31 || Pirates ||1–5||Meek (1–1)||Dickey (2–6)|| ||26,198||25–29||Boxscore |- |- align="center" bgcolor="ffbbbb" | 55 || June 1 || Pirates ||3–9||Correia (8–4) ||Capuano (3–6) || ||25,234||25–30 ||Boxscore |- align="center" bgcolor="bbffbb" | 56 || June 2 || Pirates ||9–8|| Isringhausen (1–0) || Veras (1–2) || Rodríguez (16) ||30,074||26–30||Boxscore |- align="center" bgcolor="ffbbbb" | 57 || June 3 || Braves || 3–6 || Venters (4–0)|| Rodríguez (1–2) || Kimbrel (17) || 28,301 || 26–31 || Boxscore |- align="center" bgcolor="bbffbb" | 58 || June 4 || Braves || 5–0 || Gee (6–0) || Jurrjens (7–2) || || 28,114 || 27–31 || Boxscore |- align="center" bgcolor="bbffbb" | 59 || June 5 || Braves || 6–4 || Dickey (3–6) || Hudson (4–5) || || 21,015 || 28–31 || Boxscore |- align="center" bgcolor="bbffbb" | 60 || June 7 || @ Brewers || 2–1 || Capuano (4–6) || Estrada (1–2) || Rodríguez (17) || 27,064 || 29–31 || Boxscore |- align="center"