51–74 |- bgcolor="ffbbbb" | 126 || August 19|| Boston Red Sox || L 1–7 || Miller (5–1) || Francis (4–14) || Aceves (2) || 21,262 || 51–75 |- bgcolor="bbffbb" | 127 || August 20|| Boston Red Sox || W 9–4 || Paulino (2–9) || Albers (4–4) || || 28,588 || 52–75 |- bgcolor="ffbbbb" | 128 || August 21|| Boston Red Sox || L 1–6 || Lester (13–6) || Duffy (3–8) || || 25,723 || 52–76 |- bgcolor="bbffbb" | 129 || August 23|| @ Toronto Blue Jays || W 6–4 || Chen (9–5) || Morrow (9–8) || Soria (23) || 20,009 || 53–76 |- bgcolor="ffbbbb" | 130 || August 24|| @ Toronto Blue Jays || L 3–4 || Litsch (5–3) || Coleman (1–3) || Francisco (11) || 18,292 || 53–77 |- bgcolor="bbffbb" | 131 || August 25|| @ Toronto Blue Jays || W 9–6 || Francis (5–14) || Cecil (4–7) || || 17,355 || 54–77 |- bgcolor="ffbbbb" | 132 || August 26|| @ Cleveland Indians || L 1–2 || Jiménez (8–10) || Paulino (2–10) || C. Perez (28) || 41,337 || 54–78 |- bgcolor="ffbbbb" | 133 || August 27|| @ Cleveland Indians || L 7–8 || Smith (3–3) || Coleman (1–4) || C. Perez (29) || 35,370 || 54–79 |- bgcolor="bbffbb" | 134 || August 28|| @ Cleveland Indians || W 2–1 || Chen (10–5) || Masterson (10–8) || Soria (24) || 27,908 || 55–79 |- bgcolor="bbffbb" | 135 || August 29|| @ Detroit Tigers || W 9–5 || Hochevar (9–10) || Scherzer (13–8) || Wood (1) || 32,423 || 56–79 |- bgcolor="ffbbbb" | 136 || August 30|| @ Detroit Tigers || L 1–2 (10) || Benoit (4–3) || Crow (3–4) || || 34,866 || 56–80 |- bgcolor="ffbbbb" | 137 || August 31|| @ Detroit Tigers || L 4–5 || Schlereth (2–1) || Wood (5–2) || Valverde (40) || 33,572 || 56–81 |- |- bgcolor="bbffbb" | 138 || September 1|| @ Detroit Tigers || W 11–8 || Crow (3–4) || Coke (2–9) || Soria (25) || 39,084 || 57–81 |- bgcolor="ffbbbb" | 139 || September 2|| Cleveland Indians || L 4–5 || Masterson (11–8) || Chen (10–6) || Perez (31) || 27,251 || 57–82 |- bgcolor="bbffbb" | 140 || September 3|| Cleveland Indians || W 5–1 || Hochevar (10–10) || Huff (2–3) || || 27,126 || 58–82 |- bgcolor="ffbbbb" | 141 || September 4|| Cleveland Indians || L 6–9 || Gómez