|| Pavano (6–7) || || 40,149|| 52–46 |- bgcolor="bbffbb" | 99 || July 22 || @ Twins || W 8–2 || Scherzer (11–5) || Duensing (7–8) || || 40,691 || 53–46 |- bgcolor="ffbbbb" | 100 || July 23 || @ Twins || L 4–1 || Baker (8–5) || Penny (7–7) || Nathan (7) || 40,764 || 53–47 |- bgcolor="bbffbb" | 101 || July 24 || @ Twins || W 5–2 || Porcello (10–6) || Liriano (6–8) || Valverde (26) || 40,789 || 54–47 |- bgcolor="ffbbbb" | 102 || July 25 || @ White Sox || L 6–3 || Buehrle (8–5) || Below (0–1) || || 37,110 || 54–48 |- bgcolor="bbffbb" | 103 || July 26 || @ White Sox || W 5–4 || Verlander (14–5) || Ohman (0–2) || Valverde (27) || 28,093 || 55–48 |- bgcolor="ffbbbb" | 104 || July 27 || @ White Sox || L 2–1 || Danks (4–8) || Scherzer (11–6) || Santos (21) || 26,978 || 55–49 |- bgcolor="ffbbbb" | 105 || July 28 || Angels || L 12–7 || Cassevah (1–0) || Penny (7–8) || || 33,489 || 55–50 |- bgcolor="bbffbb" | 106 || July 29 || Angels || W 12–2 || Porcello (11–6) || Chatwood (6–7) || || 40,551 || 56–50 |- bgcolor="ffbbbb" | 107 || July 30 || Angels || L 5–1 || Haren (11–6) || Turner (0–1) || || 40,753 || 56–51 |- bgcolor="bbffbb" | 108 || July 31 || Angels || W 3–2 || Verlander (15–5) || Weaver (14–5) || Valverde (28) || 36,878 || 57–51 |- |- bgcolor="bbffbb" | 109 || August 2 || Rangers || W 6–5 || Benoit (3–3) || Adams (3–2) || Valverde (29) || 29,067 || 58–51 |- bgcolor="bbffbb" | 110 || August 3 || Rangers || W 5–4 || Fister (4–12) || Harrison (9–8) || Valverde (30) || 33,596 || 59–51 |- bgcolor="ffbbbb" | 111 || August 4 || Rangers || L 5–2 || Ogando (11–5) || Penny (7–9) || Feliz (22) || 40,497 || 59–52 |- bgcolor="bbffbb" | 112 || August 5 || @ Royals || W 4–3 (10) || Schlereth (1–1) || Crow (3–3) || Valverde (31) || 28,565 || 60–52 |- bgcolor="bbffbb" | 113 || August 6 || @ Royals || W 4–3 || Verlander (16–5) || Duffy (3–5) || Valverde (32) || 25,818 || 61–52 |- bgcolor="ffbbbb" | 114 || August 7 || @ Royals || L 4–3 || Chen