(6–5) || Scherzer (11–7) || Soria (21) || 20,132 || 61–53 |- bgcolor="ffbbbb" | 115 || August 9 || @ Indians || L 3–2 (14) || Herrmann (3–0) || Pauley (5–5) || || 25,317 || 61–54 |- bgcolor="ffbbbb" | 116 || August 10 || @ Indians || L 10–3 || Jiménez (7–9) || Porcello (11–7) || || 23,258 || 61–55 |- bgcolor="bbffbb" | 117 || August 11 || @ Indians || W 4–3 || Verlander (17–5) || Carmona (5–12) || Valverde (33) || 30,988 || 62–55 |- bgcolor="bbffbb" | 118 || August 12 || @ Orioles || W 5–4 || Penny (8–9) || Patton (0–1) || Valverde (34) || 21,465 || 63–55 |- bgcolor="bbffbb" | 119 || August 13 || @ Orioles || W 6–5 || Scherzer (12–7) || Guthrie (5–16) || Valverde (35) || 24,114 || 64–55 |- bgcolor="ffbbbb" | 120 || August 14 || @ Orioles || L 8–5 || Reyes (6–9) || Fister (4–13) || Johnson (2) || 18,348 || 64–56 |- bgcolor="ffbbbb" | 121 || August 15 || Twins || L 9–6 || Liriano (8–9) || Porcello (11–8) || Nathan (10) || 36,211 || 64–57 |- bgcolor="bbffbb" | 122 || August 16 || Twins || W 7–1 || Verlander (18–5) || Blackburn (6–10) || || 40,589 || 65–57 |- bgcolor="ffbbbb" | 123 || August 17 || Twins || L 6–5 || Capps (4–6) || Valverde (2–4) || Nathan (11) || 34,835 || 65–58 |- bgcolor="bbffbb" | 124 || August 19 || Indians || W 4–1 || Scherzer (13–7) || Tomlin (12–6) || Valverde (36) || 44,222 || 66–58 |- bgcolor="bbffbb" | 125 || August 20 || Indians || W 10–1 || Fister (5–13) || Huff (1–2) || || 44,629 || 67–58 |- bgcolor="bbffbb" | 126 || August 21 || Indians || W 8–7 || Coke (2–8) || Jiménez (7–10) || Valverde (37) || 43,388 || 68–58 |- bgcolor="bbffbb" | 127 || August 22 || @ Rays || W 5–2 || Verlander (19–5) || Niemann (8–5) || || 13,048 || 69–58 |- bgcolor="bbffbb" | 128 || August 23 || @ Rays || W 2–1 || Penny (9–9) || Price (11–11) || Coke (1) || 11,475 || 70–58 |- bgcolor="ffbbbb" | 129 || August 24 || @ Rays || L 3–2 (10) || Peralta (3–4) || Below (0–2) || || 13,910 || 70–59 |- bgcolor="bbffbb" | 130 || August 25 || @ Rays || W 2–0 || Fister