style="background:#cfc;" | 49 || May 27 || @ Cubs || 4–2 || Correia (7–4) || Davis (0–3) || Hanrahan (14) || 34,105 || 23–26 |- style="background:#cfc;" | 50 || May 28 || @ Cubs || 10–0 || Maholm (2–7) || Wells (1–1) || — || 38,413 || 24–26 |- style="background:#fbb;" | 51 || May 29 || @ Cubs || 2–3 || Dempster (4–4) || Karstens (3–4) || Marmol (10) || 37,464 || 24–27 |- style="background:#fbb;" | 52 || May 30 || @ Mets || 3–7 || Gee (5–0) || McCutchen (1–1) || — || 24,490 || 24–28 |- style="background:#cfc;" | 53 || May 31 || @ Mets || 5–1 || Meek (1–1) || Dickey (2–6) || — || 26,198 || 25–28 |- |- style="background:#cfc;" | 54 || June 1 || @ Mets || 9–3 || Correia (8–4) || Capuano (3–6) || — || 25,234 || 26–28 |- style="background:#fbb;" | 55 || June 2 || @ Mets || 8–9 || Isringhausen (1–0) || Veras (1–2) || Rodriguez (16) || 30,074 || 26–29 |- style="background:#cfc;" | 56 || June 3 || Phillies || 2–1 (12) || Moskos (1–0) || Baez (1–3) || — || 33,861 || 27–29 |- style="background:#cfc;" | 57 || June 4 || Phillies || 6–3 || Morton (6–2) || Kendrick (3–4) || — || 39,441 || 28–29 |- style="background:#fbb;" | 58 || June 5 || Phillies || 3–7 || Halladay (8–3) || McDonald (3–4) || — || 35,505 || 28–30 |- style="background:#cfc;" | 59 || June 7 || D-backs || 8–5 || Resop (2–1) || Hernandez (2–2) || Hanrahan (15) || 12,378 || 29–30 |- style="background:#cfc;" | 60 || June 8 || D-backs || 3–2 (12) || McCutchen (2–1) || Kroenke (0–1) || — || 14,015 || 30–30 |- style="background:#fbb;" | 61 || June 9 || D-backs || 0–2 || Owings (2–0) || Resop (2–2) || Hernandez (2) || 12,468 || 30–31 |- style="background:#fbb;" | 62 || June 10 || Mets || 1–8 || Gee (7–0) || Morton (6–3) || — || 24,653 || 30–32 |- style="background:#cfc;" | 63 || June 11 || Mets || 3–2 || McDonald (4–4) || Dickey (3–7) || Hanrahan (16) || 39,273 || 31–32 |- style="background:#fbb;" | 64 || June 12 || Mets || 0–7 || Capuano (5–6) || Correia (8–5) || — || 26,452 || 31–33 |- style="background:#cfc;" | 65 || June 13 || Mets || 3–1 || Maholm (3–7) || Pelfrey (3–5)