(0–1) || || 21,411 || 78–53 |- align="center" bgcolor="ffbbbb" | 132 || August 24 || @ Pirates || 2–0 || Grilli (1–0) || Marcum (11–4) || Hanrahan (32) || 18,013 || 78–54 |- align="center" bgcolor="bbffbb" | 133 || August 26 || Cubs || 5–2 || Wolf (11–8) || López (4–5) || Axford (38) || 41,661 || 79–54 |- align="center" bgcolor="bbffbb" | 134 || August 27 || Cubs || 6–4 || Gallardo (15–8) || Dempster (10–10) || Axford (39) || 44,091 || 80–54 |- align="center" bgcolor="bbffbb" | 135 || August 28 || Cubs || 3–2 || Greinke (13–5) || Coleman (2–7) || Axford (40) || 41,883 || 81–54 |- align="center" bgcolor="ffbbbb" | 136 || August 30 || Cardinals || 2–1 || Jackson (11–9) || Marcum (11–5) || Salas (23) || 42,384 || 81–55 |- align="center" bgcolor="ffbbbb" | 137 || August 31 || Cardinals || 8–3 || Westbrook (11–7) || Wolf (11–9) || || 38,073 || 81–56 |- align="center" bgcolor="ffbbbb" | 138 || September 1 || Cardinals || 8–4 || Dotel (3–3) || Gallardo (15–9) || || 34,080 || 81–57 |- align="center" bgcolor="bbffbb" | 139 || September 2 || @ Astros || 8–2 || Greinke (14–5) || Rodríguez (1–6) || || 20,045 || 82–57 |- align="center" bgcolor="bbffbb" | 140 || September 3 || @ Astros || 8–2 || Narveson (10–6) || Norris (6–9) || || 24,982 || 83–57 |- align="center" bgcolor="bbffbb" | 141 || September 4 || @ Astros || 4–0 || Marcum (12–5) || Rodríguez (10–10) || || 21,976 || 84–57 |- align="center" bgcolor="bbffbb" | 142 || September 5 || @ Cardinals || 4–1 || Wolf (12–9) || Westbrook (11–8) || Axford (41) || 42,043 || 85–57 |- align="center" bgcolor="ffbbbb" | 143 || September 6 || @ Cardinals || 4–2 || Lohse (13–8) || Gallardo (15–10) || Motte (3) || 35,397 || 85–58 |- align="center" bgcolor="ffbbbb" | 144 || September 7 || @ Cardinals || 2–0 || Carpenter (9–9) || Greinke (14–6) || || 38,891 || 85–59 |- align="center" bgcolor="ffbbbb" | 145 || September 8 || Phillies || 7–2 || Hamels (14–7) || Narveson (10–7) || || 41,646 || 85–60 |- align="center" bgcolor="ffbbbb" | 146 || September 9 || Phillies || 5–3 || Halladay (17–5) || Marcum (12–6) || Madson (29) || 43,283 || 85–61 |- align="center" bgcolor="ffbbbb" | 147 || September 10 || Phillies || 3–2 (10) || Stutes (6–1) || Hawkins (1–1) || Madson (30) || 42,967 || 85–62