|| June 7 || @ Giants || 2–1 || Zimmermann (4–6) || Sánchez (4–4) || Storen (12) || 41,786 || 27–34 |- align="center" bgcolor="ffbbbb" | 62 || June 8 || @ Giants || 3–1 || Cain (5–4) || Burnett (1–3) || || 41,738 || 27–35 |- align="center" bgcolor="ffbbbb" | 63 || June 9 || @ Padres || 7–3 || Harang (7–2) || Hernández (3–8) || || 16,464 || 27–36 |- align="center" bgcolor="bbffbb" | 64 || June 10 || @ Padres || 2–1 || Marquis (7–2) || Latos (4–7) || Storen (13) || 23,211 || 28–36 |- align="center" bgcolor="bbffbb" | 65 || June 11 || @ Padres || 2–1 || Lannan (4–5) || Richard (2–8) || Storen (14) || 25,027 || 29–36 |- align="center" bgcolor="bbffbb" | 66 || June 12 || @ Padres || 2–0 || Coffey (2–0) || Bell (2–3) || Storen (15) || 20,185 || 30–36 |- align="center" bgcolor="bbffbb" | 67 || June 14 || Cardinals || 8–6 || Rodríguez (2–1) || Batista (3–2) || Storen (16) || 26,739 || 31–36 |- align="center" bgcolor="bbffbb" | 68 || June 15 || Cardinals || 10 – 0 || Hernández (4–8) || McClellan (6–3) || || 27,130 || 32–36 |- align="center" bgcolor="bbffbb" | 69 || June 16 || Cardinals || 7–4 (10) || Burnett (2–3) || Salas (3–1) || || 19,662 || 33–36 |- align="center" bgcolor="bbffbb" | 70 || June 17 || Orioles || 8–4 || Burnett (3–3) || Accardo (3–3) || || 35,562 || 34–36 |- align="center" bgcolor="bbffbb" | 71 || June 18 || Orioles || 4–2 || Zimmermann (5–6) || Matusz (1–2) || Storen (17) || 36,614 || 35–36 |- align="center" bgcolor="ffbbbb" | 72 || June 19 || Orioles || 7–4 || Jakubauskas (2–0) || Gorzelanny (2–5) || || 35,439 || 35–37 |- align="center" bgcolor="bbffbb" | 73 || June 21 || Mariners || 6–5 || Coffey (3–0) || Pauley (4–1) || || 21,502 || 36–37 |- align="center" bgcolor="bbffbb" | 74 || June 22 || Mariners || 2–1 || Lannan (5–5) || Bédard (4–5) || Storen (18) || 21,367 || 37–37 |- align="center" bgcolor="bbffbb" | 75 || June 23 || Mariners || 1–0 || Clippard (1–0) || Ray (3–2) || || 21,161 || 38–37 |- align="center" bgcolor="bbffbb" | 76 || June 24 || @ White Sox || 9–5 (14) || Balester (1–0) || Thornton (0–4) || || 23,856 || 39–37 |- align="center" bgcolor="ffbbbb" | 77 || June 25 || @ White