|- align="center" bgcolor="ffbbbb" | 135 || August 30 || Phillies || FSO || L 0–9 || Halladay (16–5) || Arroyo (8–11) || || 19,317 || 67–68 || |- align="center" bgcolor="ffbbbb" | 136 || August 31 || Phillies || FSO || L 0–3 || Lee (15–7) || Willis (0–4) || Madson (25) || 18,567 || 67–69 || |- |- align="center" bgcolor="ffbbbb" | 137 || September 1 || Phillies || FSO || L 4–6 || Worley (10–1) || Leake (11–9) || Madson (26) || 21,438 || 67–70 || |- align="center" bgcolor="bbffbb" | 138 || September 2 || @ Cardinals || FSO || W 11–8 || Arredondo (4–4) || Rzepczynski (2–4) || || 36,970 || 68–70 || |- align="center" bgcolor="ffbbbb" | 139 || September 3 || @ Cardinals || Fox || L 4–6 || García (11–7) || Bailey (7–7) || Motte (2) || 41,839 || 68–71 || |- align="center" bgcolor="bbffbb" | 140 || September 4 || @ Cardinals || FSO || W 3–2 (10) || Bray (5–2) || Salas (5–6) || Cordero (30) || 41,647 || 69–71 || |- align="center" bgcolor="ffbbbb" | 141 || September 5 || @ Cubs || FSO || L 3–4 || Garza (8–10) || Willis (0–5) || Mármol (32) || 41,341 || 69–72 || |- align="center" bgcolor="bbffbb" | 142 || September 6 || @ Cubs || FSO || W 4–2 (13) || Chapman (4–1) || Grabow (3–1) || Cordero (31) || 35,297 || 70–72 || |- align="center" bgcolor="ffbbbb" | 143 || September 7 || @ Cubs || FSO || L 3–6 || Wood (2–5) || Ondrusek (4–5) || Mármol (33) || 36,797 || 70–73 || |- align="center" bgcolor="bbffbb" | 144 || September 9 || @ Rockies || FSO || W 4–1 || Bailey (8–7) || Chacín (11–11) || Cordero (32) || 39,933 || 71–73 || |- align="center" bgcolor="ffbbbb" | 145 || September 10 || @ Rockies || || L 7–12 || White (3–1) || Maloney (0–2) || || 38,407 || 71–74 || |- align="center" bgcolor="ffbbbb" | 146 || September 11 || @ Rockies || FSO || L 1–4 || Pomeranz (1–0) || Vólquez (5–5) || Hammel (1) || 39,240 || 71–75 || |- align="center" bgcolor="ffbbbb" | 147 || September 12 || Cubs || FSO || L 8–12 || López (5–6) || Willis (0–6) || || 19,874 || 71–76 || |- align="center" bgcolor="bbffbb" | 148 || September 13 || Cubs || FSO || W 2–1 || Leake (12–9) || Dempster