39–57 |- style="text-align:center; background:#cfc;" | 97 || July 23 || Angels || 3–2 || Bergesen (2–6) || Piñeiro (5–5) || Gregg (16) || 20,311 || 40–57 |- style="text-align:center; background:#fbb;" | 98 || July 24 || Angels || 3–9 || Chatwood (6–6) || Guthrie (4–14) || || 15,676 || 40–58 |- style="text-align:center; background:#cfc;" | 99 || July 26 || @ Blue Jays || 12–4 || Arrieta (10–7) || Morrow (7–5) || || 17,477 || 41–58 |- style="text-align:center; background:#fbb;" | 100 || July 27 || @ Blue Jays || 0–3 || Romero (8–9) || Simón (2–4) || Rauch (8) || 16,861 || 41–59 |- style="text-align:center; background:#fbb;" | 101 || July 28 || @ Blue Jays || 5–8 || Villanueva (6–2) || Bergesen (2–7) || || 16,152 || 41–60 |- style="text-align:center; background:#cfc;" | 102 || July 29 || @ Yankees || 4–2 || Guthrie (5–14) || Burnett (8–9) || Gregg (17) || 46,499 || 42–60 |- style="text-align:center; background:#fbb;" | 103 || July 30 || @ Yankees || 3–8 || Colón (8–6) || Tillman (2–4) || || 46,469 || 42–61 |- style="text-align:center; background:#fbb;" | 104 || July 30 || @ Yankees || 3–17 || Nova (9–4) || Britton (6–8) || || 43,190 || 42–62 |- style="text-align:center; background:#fbb;" | 105 || July 31 || @ Yankees || 2–4 || García (10–7) || Arrieta (10–8) || Rivera (27) || 46,913 || 42–63 |- |- style="text-align:center; background:#cfc;" | 106 || August 2 || @ Royals || 8–2 || Simón (3–4) || Chen (5–5) || || 17,116 || 43–63 |- style="text-align:center; background:#fbb;" | 107 || August 3 || @ Royals || 2–6 || Hochevar (8–8) || Guthrie (5–15) || Holland (1) || 14,187 || 43–64 |- style="text-align:center; background:#fbb;" | 108 || August 4 || @ Royals || 4–9 || Wood (5–0) || Britton (6–9) || || 12,161 || 43–65 |- style="text-align:center; background:#fbb;" | 109 || August 5 || Blue Jays || 4–5 || Mills (1–1) || Hunter (1–2) || Rauch (11) || 18,770 || 43–66 |- style="text-align:center; background:#cfc;" | 110 || August 6 || Blue Jays || 6–2 || Tillman (3–4) || Morrow (8–6) || || 19,396 || 44–66 |- style="text-align:center; background:#fbb;" | 111 || August 7 || Blue Jays || 2–7 || Romero (10–9) || Simón (3–5) || || 13,824 || 44–67 |- style="text-align:center; background:#fbb;" | 112 || August 8 || White Sox || 6–7 || Crain (6–3) || Johnson (5–4) || Santos (23) || 17,498 ||