|| Hanrahan (17) || 15,555 || 32–33 |- style="background:#cfc;" | 66 || June 14 || @ Astros || 1–0 || Karstens (4–4) || Norris (4–5) || Hanrahan (18) || 29,712 || 33–33 |- style="background:#cfc;" | 67 || June 15 || @ Astros || 7–3 || Morton (7–3) || Del Rosario (0–1) || Hanrahan (19) || 29,866 || 34–33 |- style="background:#cfc;" | 68 || June 16 || @ Astros || 5–4 || McDonald (5–4) || Lyles (0–2) || Veras (1) || 26,415 || 35–33 |- style="background:#fbb;" | 69 || June 17 || @ Indians || 1–5 || Tomlin (8–4) || Correia (8–6) || — || 38,549 || 35–34 |- style="background:#fbb;" | 70 || June 18 || @ Indians || 1–5 || Carrasco (7–3) || Maholm (3–8) || — || 31,865 || 35–35 |- style="background:#fbb;" | 71 || June 19 || @ Indians || 2–5 (11) || Sipp (3–0) || Wood (0–1) || — || 30,023 || 35–36 |- style="background:#fbb;" | 72 || June 20 || Orioles || 3–8 || Arrieta (9–4) || Morton (7–4) || — || 22,447 || 35–37 |- style="background:#cfc;" | 73 || June 21 || Orioles || 9–3 || Resop (3–2) || Guthrie (2–9) || — || 33,806 || 36–37 |- style="background:#cfc;" | 74 || June 22 || Orioles || 5–4 || Correia (9–6) || Britton (6–5) || Hanrahan (20) || 19,418 || 37–37 |- style="background:#cfc;" | 75 || June 24 || Red Sox || 3–1 || Maholm (4–8) || Lester (9–4) || Hanrahan (21) || 39,330 || 38–37 |- style="background:#cfc;" | 76 || June 25 || Red Sox || 6–4 || Karstens (5–4) || Wakefield (4–3) || Hanrahan (22) || 39,483 || 39–37 |- style="background:#fbb;" | 77 || June 26 || Red Sox || 2–4 || Miller (1–0) || Wood (0–2) || Papelbon (14) || 39,511 || 39–38 |- style="background:#cfc;" | 78 || June 28 || @ Blue Jays || 7–6 || Correia (10–6) || Reyes (3–7) || Hanrahan (23) || 17,085 || 40–38 |- style="background:#fbb;" | 79 || June 29 || @ Blue Jays || 1–2 || Morrow (4–4) || Maholm (4–9) || Francisco (9) || 15,632 || 40–39 |- style="background:#cfc;" | 80 || June 30 || @ Blue Jays || 6–2 || Karstens (6–4) || Cecil (1–3) || — || 14,939 || 41–39 |- |- style="background:#fbb;" | 81 || July 1 || @ Nationals || 1–2 || Storen (5–2) || Wood (0–3) || — ||