into pharmaceuticals using “target-free” drug discovery. Using this approach, drugs are sought in a cellular context, with no preconceived notions of what targets within the cell are relevant. Institut Pasteur Korea joined the Institut Pasteur International Network in November 2004 as a private foundation recognized as working toward the public good through biomedical research. Until April 2009, Institut Pasteur Korea was located in a small facility on the campus of KIST. It then moved into a new 15,199 square meter facility in Pangyo, Gyeonggi Province. The institute is one of the few in the world that contains robotic, high throughput optical imaging capacity within biosafety level 2 and 3 facilities. Organization Institut Pasteur Korea is organized into three divisions, Discovery Biology, Translation Research and Administration. These functional units collaborate across disciplines and classical research boundaries, providing an effective operational organization to meet the strategic goals of the institute. Research and technology Institut Pasteur Korea’s target identification technology uses high-content, genome-wide visual arrays to identify targets of interest in live cellular disease models. By screening with siRNA libraries, researchers can identify genes that alter drug sensitivity in the cellular disease model, thereby providing a way to quickly close in on the molecular targets. Institut Pasteur Korea’s Discovery Chemistry group applies new concepts of drug design to optimize hit-to-lead identification. Its drug discovery technology platforms have led to the first-ever TB chemical screen performed using primary macrophages and resulting in a new best-in-class molecule to fight TB, referred to as Q203. Financial support Institut Pasteur Korea is funded through Korean government subsidies from the Ministry of Science and ICT, domestic and international grants, revenues from industry-sponsored research and license agreements, and donations. References Medical research institutes Medical and health organizations based in South Korea Research institutes in South Korea Korea