Royals || 1–2 || Teaford (1–0) || Vasquez (1–3) || Soria (28) || 20,591 || 61–85 || |- style="text-align:center; background:#fbb;" | 147 || September 12 || Yankees || 3–9 || Hughes (5–5) || Hernández (14–12) || || 22,029 || 61–86 || |- style="text-align:center; background:#fbb;" | 148 || September 13 || Yankees || 2–3 || Burnett (10–11) || Furbush (3–9) || Rivera (41) || 18,306 || 61–87 || |- style="text-align:center; background:#bfb;" | 149 || September 14 || Yankees || 2–1 (12) || Delabar (1–0) || Wade (5–1) || || 20,327 || 62–87 || |- style="text-align:center; background:#bfb;" | 150 || September 16 || Rangers || 4–0 || Beavan (5–5) || Wilson (16–7) || || 17,607 || 63–87 || |- style="text-align:center; background:#fbb;" | 151 || September 17 || Rangers || 6–7 || Lewis (13–10) || Vasquez (1–4) || Feliz (27) || 22,159 || 63–88 || |- style="text-align:center; background:#fbb;" | 152 || September 18 || Rangers || 0–3 || Harrison (13–9) || Hernández (14–13) || Feliz (28) || 21,479 || 63–89 || |- style="text-align:center; background:#bfb;" | 153 || September 19 || @ Indians || 12–6 (7) || Furbush (4–9) || Huff (2–6) || || 15,354 || 64–89 || |- style="text-align:center; background:#bfb;" | 154 || September 20 || @ Twins || 5–4 || Vargas (9–13) || Duensing (9–14) || League (35) || 35,995 || 65–89 || |- style="text-align:center; background:#bfb;" | 155 || September 21 || @ Twins || 5–4 || Jimenez (1–0) || Slowey (0–7) || League (36) || 36,263 || 66–89 || |- style="text-align:center; background:#fbb;" | 156 || September 22 || @ Twins || 2–3 || Nathan (2–1) || Delabar (1–1) || || 37,466 || 66–90 || |- style="text-align:center; background:#fbb;" | 157 || September 23 || @ Rangers || 3–5 || Harrison (14–9) || Vasquez (1–5) || Feliz (30) || 43,874 || 66–91 || |- style="text-align:center; background:#fbb;" | 158 || September 24 || @ Rangers || 3–7 || Feldman (2–1) || Hernández (14–14) || || 40,242 || 66–92 || |- style="text-align:center; background:#fbb;" | 159 || September 25 || @ Rangers || 5–12 || Holland (16–5) || Furbush (4–10) || || 43,508 || 66–93 || |- style="text-align:center; background:#bfb;" | 160 || September 26 || Athletics || 4–2 || Vargas (10–13) || McCarthy (9–9) || League (36) || 17,057 || 67–93 || |- style="text-align:center; background:#fbb;" | 161 || September 27 || Athletics || 0–7 || Cahill (12–14) || Beavan (5–6) || || 18,600 || 67–94 ||