12–3 || Arroyo (1–0) || Wolf (0–1) || || 24,805 || 0–3 |- align="center" bgcolor="ffbbbb" | 4 || April 4 || Braves || 2–1 || Moylan (1–0) || Saito (0–1) || Kimbrel (1) || 46,017 || 0–4 |- align="center" bgcolor="bbffbb" | 5 || April 5 || Braves || 1–0 || Gallardo (1–0) || Lowe (1–1) || || 24,117 || 1–4 |- align="center" bgcolor="bbffbb" | 6 || April 6 || Braves || 5–4 || Estrada (1–0) || Minor (0–1) || Axford (1) || 23,420 || 2–4 |- align="center" bgcolor="bbffbb" | 7 || April 7 || Braves || 4–2 || Marcum (1–1) || Hanson (0–1) || Axford (2) || 24,645 || 3–4 |- align="center" bgcolor="ffbbbb" | 8 || April 8 || Cubs || 7–4 || Zambrano (1–0) || Wolf (0–2) || Mármol (3) || 34,310 || 3–5 |- align="center" bgcolor="bbffbb" | 9 || April 9 || Cubs || 6–0 || Narveson (1–0) || Garza (0–1) || || 42,478 || 4–5 |- align="center" bgcolor="bbffbb" | 10 || April 10 || Cubs || 6–5 || Loe (1–0) || Wood (0–1) || Axford (3) || 37,193 || 5–5 |- align="center" bgcolor="bbbbbb" | – || April 12 || @ Pirates || colspan=6| Postponed (rain); Makeup: August 22 |- align="center" bgcolor="bbffbb" | 11 || April 13 || @ Pirates || 6–0 || Marcum (2–1) || Correia (2–1) || || 8,755 || 6–5 |- align="center" bgcolor="bbffbb" | 12 || April 14 || @ Pirates || 4–1 || Wolf (1–2) || Maholm (0–2) || || 10,517 || 7–5 |- align="center" bgcolor="ffbbbb" | 13 || April 15 || @ Nationals || 4–3 (10) || Gaudin (1–1) || Braddock (0–1) || || 17,217 || 7–6 |- align="center" bgcolor="bbbbbb" | – || April 16 || @ Nationals || colspan=6| Postponed (rain); Makeup: April 17 |- align="center" bgcolor="ffbbbb" | 14 || April 17 || @ Nationals || 8–4 || Marquis (1–0) || Gallardo (1–1)|| || n/a || 7–7 |- align="center" bgcolor="ffbbbb" | 15 || April 17 || @ Nationals || 5–1 || Hernández (2–1) || Loe (1–1) || Storen (1) || 23,047 || 7–8 |- align="center" bgcolor="bbffbb" | 16 || April 18 || @ Phillies || 6–3 (12) || Kintzler (1–0) || Kendrick (0–1) || || 45,637 || 8–8 |- align="center" bgcolor="bbffbb" | 17 || April 19 || @ Phillies || 9–0 || Wolf (2–2) || Halladay (2–1) || || 45,408 || 9–8 |- align="center" bgcolor="ffbbbb" | 18 || April 20 || @