| -- || April 15 || @ Braves||colspan=7|Game Postponed (rain) (to be made up as a doubleheader on 4/16) |- align="center" bgcolor="ffbbbb" | 14 || April 16 || @ Braves|| 2–4 || Lowe (2–2)||Carrasco (0–1) || Kimbrel (4) || || 4–10 || Boxscore |- align="center" bgcolor="ffbbbb" | 15 || April 16 || @ Braves|| 0–4 || Jurrjens (1–1) || Pelfrey (0–2) || || 31,383 || 4–11 || Boxscore |- align="center" bgcolor="bbffbb" | 16 || April 17 || @ Braves|| 3–2 ||Gee (1–0)||Hanson (1–2)||Rodríguez (2)|| 29,625 || 5–11 || Boxscore |- align="center" bgcolor="ffbbbb" | 17 || April 19 || Astros|| 1–6 || Rodríguez (1–2)|| Niese (0–3)|| ||27,032|| 5–12 || Boxscore |- align="center" bgcolor="ffbbbb" | 18 || April 20 || Astros|| 3–4 || Melancon (2–1)|| Dickey (1–3) || Lyon (4)||27,380||5–13|| Boxscore |- align="center" bgcolor="bbffbb" | 19 || April 21 || Astros|| 9–1 || Capuano (2–1) || Happ (1–3) || || 32,819 || 6–13 || Boxscore |- align="center" bgcolor="bbffbb" | 20 || April 22 || Diamondbacks|| 4–1 || Pelfrey (1–2) || Vásquez (0–1) || Rodríguez (3) || 26,546 || 7–13 || Boxscore |- align="center" bgcolor="bbffbb" | 21 || April 23 || Diamondbacks|| 6–4 || Gee (2–0) || Enright (0–2) || Rodríguez (4) || 25,581 || 8–13 || Boxscore |- align="center" bgcolor="bbffbb" | 22 || April 24 || Diamondbacks|| 8–4 || Niese (1–3) || Galarraga (3–1) || || 22,232 || 9–13 || Boxscore |- align="center" bgcolor="bbffbb" | 23 || April 26 || @ Nationals|| 6–4 || Igarashi (1–0) || Zimmermann (1–4) || Rodríguez (5) || 14,603 || 10–13 || Boxscore |- align="center" bgcolor="bbffbb" | 24 || April 27 || @ Nationals|| 6–3 || Beato (1–0) || Burnett (0–1) || Rodríguez (6) || 13,568 || 11–13 || Boxscore |- align="center" bgcolor="ffbbbb" | 25 || April 28 || @ Nationals|| 3–4 || Hernández (3–2) || Capuano (2–2) || Storen (4) || 15,142 || 11–14 || Boxscore |- align="center" bgcolor="ffbbbb" | 26 || April 29 || @ Phillies|| 3–10 || Worley (1–0) || Pelfrey (1–3) || || 45,613 || 11–15 || Boxscore |- align="center" bgcolor="ffbbbb" | 27 || April 30 || @ Phillies|| 1–2 || Halladay (4–1) || Niese (1–4) || || 45,598 || 11–16 || Boxscore |- |- align="center" bgcolor="bbffbb" | 28 || May 1 || @ Phillies || 2–1 (14) || Buchholz (1–0) || Kendrick (1–2) || || 45,713 ||12–16|| Boxscore |- align="center" bgcolor="ffbbbb" | 29 || May 3 || Giants || 6–7 (10) ||