|| Greinke (3–1) || Marquis (5–2) || Loe (1) || 34,419 || 27–23 |- align="center" bgcolor="ffbbbb" | 51 || May 27 || Giants || 5–4 || Lincecum (5–4) || Marcum (6–2) || Wilson (14) || 37,034 || 27–24 |- align="center" bgcolor="bbffbb" | 52 || May 28 || Giants || 3–2 || Axford (1–1) || Mota (2–2) || || 42,512 || 28–24 |- align="center" bgcolor="bbffbb" | 53 || May 29 || Giants || 6–0 || Gallardo (7–2) || Cain (3–4) || || 43,035 || 29–24 |- align="center" bgcolor="ffbbbb" | 54 || May 30 || @ Reds || 7–3 || Wood (4–3) || Narveson (2–4) || || 21,564 || 29–25 |- align="center" bgcolor="bbffbb" | 55 || May 31 || @ Reds || 7–2 || Greinke (4–1) || Reineke (0–1) || || 14,294 || 30–25 |- align="center" bgcolor="ffbbbb" | 56 || June 1 || @ Reds || 4–3 || Masset (1–3) || Loe (2–5) || Cordero (10) || 22,213 || 30–26 |- align="center" bgcolor="bbffbb" | 57 || June 3 || @ Marlins || 6–5 || McClendon (3–0) || Núñez (0–2) || Axford (14) || 15,315 || 31–26 |- align="center" bgcolor="bbffbb" | 58 || June 4 || @ Marlins || 3–2 || Gallardo (8–2) || Volstad (2–5) || Axford (15) || 17,200 || 32–26 |- align="center" bgcolor="bbffbb" | 59 || June 5 || @ Marlins || 6–5 (11) || Dillard (1–0) || Dunn (4–3) || Axford (16) || 13,208 || 33–26 |- align="center" bgcolor="bbffbb" | 60 || June 6 || @ Marlins || 7–2 || Greinke (5–1) || Vázquez (3–5) || || 12,404 || 34–26 |- align="center" bgcolor="ffbbbb" | 61 || June 7 || Mets || 2–1 || Capuano (4–6) || Estrada (1–3) || Rodríguez (17) || 27,064 || 34–27 |- align="center" bgcolor="bbffbb" | 62 || June 8 || Mets || 7–6 || Axford (2–1) || Thayer (0–1) || || 26,114 || 35–27 |- align="center" bgcolor="ffbbbb" | 63 || June 9 || Mets || 4–1 || Niese (5–5) || Gallardo (8–3) || Rodríguez (18) || 30,632 || 35–28 |- align="center" bgcolor="bbffbb" | 64 || June 10 || Cardinals || 8–0 || Narveson (3–4) || Lohse (7–3) || || 33,240 || 36–28 |- align="center" bgcolor="bbffbb" | 65 || June 11 || Cardinals || 5–3 || Greinke (6–1) || Carpenter (1–6) || Axford (17) || 41,930 || 37–28 |- align="center" bgcolor=" bgcolor="bbffbb" | 66 || June 12 || Cardinals || 4–3 || Marcum (7–2) || Westbrook