@ Phillies ||colspan=6| Postponed (rain); Makeup: June 15 as part of a doubleheader |- align="center" bgcolor="ffbbbb" | 14 || April 17 || @ Phillies || 2–3 || Madson (1–0) || Webb (0–2) || Contreras (3) || 45,716 || 9–5 |- align="center" bgcolor="bbffbb" | 15 || April 19 || Pirates || 6–0 || Johnson (3–0) || Maholm (0–3) || || 11,118 || 9–6 |- align="center" bgcolor="bbffbb" | 16 || April 20 || Pirates || 6–0 || Nolasco (2–0) || Morton (2–1) || || 10,112 || 10–6 |- align="center" bgcolor="bbffbb" | 17 || April 21 || Pirates || 9–5 || Volstad (1–1) || McDonald (0–2) || || 12,308 || 11–6 |- align="center" bgcolor="bbffbb" | 18 || April 22 || Rockies || 4–1 || Sánchez (1–1) || Chacín (3–1) || || 15,069 || 12–6 |- align="center" bgcolor="ffbbbb" | 19 || April 23 || Rockies || 1–3 || Hammel (2–1) || Vázquez (1–2) || Street (7) || 35,381 || 12–7 |- align="center" bgcolor="bbffbb" | 20 || April 24 || Rockies || 6–3 || Dunn (1–0) || Belisle (2–1) || Núñez (6) || 11,442 || 13–7 |- align="center" bgcolor="bbffbb" | 21 || April 25 || Dodgers || 5–4 || Sanches (3–0) || Broxton (1–1) || || 11,633 || 14–7 |- align="center" bgcolor="bbffbb" | 22 || April 26 || Dodgers || 4–2 || Volstad (2–1) || Kershaw (2–3) || Núñez (7) || 12,150 || 15–7 |- align="center" bgcolor="ffbbbb" | 23 || April 27 || Dodgers || 4–5 (10) || Guerrier (2–1) || Sanches (3–1) || Padilla (1) || 16,523 || 15–8 |- align="center" bgcolor="bbffbb" | 24 || April 29 || @ Reds || 7–6 || Vázquez (2–2) || Wood (1–3) || Núñez (8) || 27,051 || 16–8 |- align="center" bgcolor="ffbbbb" | 25 || April 30 || @ Reds || 3–4 (10) || Cordero (1–0) || Dunn (1–1) || || 40,286 || 16–9 |- |- bgcolor="ffbbbb" |- align="center" bgcolor="bbffbb" | 26 || May 1 || @ Reds || 9–5 || Nolasco (3–0) || Arroyo (3–3) || Núñez (9) || 26,941 || 17–9 |- align="center" bgcolor="bbffbb" | 27 || May 2 || @ Cardinals || 6–5 || Mujica (3–1) || Boggs (0–2) || Núñez (10) || 32,635 || 18–9 |- align="center" bgcolor="ffbbbb" | 28 || May 3 || @ Cardinals || 5–7 || Salas (1–0) || Webb (0–3) || Sánchez (2) || 32,689 || 18–10 |- align="center" bgcolor="bbffbb" | 29 || May 4 || @ Cardinals || 8–7