|| 31,572 || 35–30 |- bgcolor="bbffbb" | 66 || June 13 || Rays || W 2–1 (10) || Purcey (1–0) || Farnsworth (0–1) || || 30,938 || 36–30 |- bgcolor="bbffbb" | 67|| June 14 || Indians || W 4–0 || Verlander (8–3) || Masterson (5–5) || || 28,128 || 37–30 |- bgcolor="ffbbbb" | 68 || June 15 || Indians || L 6–4 || Carmona (4–8) || Furbush (1–1) || Perez (17) || 26,711 || 37–31 |- bgcolor="bbffbb" | 69 || June 16 || Indians || W 6–2 || Scherzer (9–2) || Talbot (2–4) || || 37,437 || 38–31 |- bgcolor="ffbbbb" | 70 || June 17 || @ Rockies || L 13–6 || Hammel (4–6) || Porcello (6–5) || || 41,594 || 38–32 |- bgcolor="ffbbbb" | 71 || June 18 || @ Rockies || L 5–4 || Jiménez (2–7) || Coke (1–7) || Street (20) || 48,555 ||38–33 |- bgcolor="bbffbb" | 72 || June 19 || @ Rockies || W 9–1 || Verlander (9–3) || Cook (0–2) || || 49,015 || 39–33 |- bgcolor="ffbbbb" | 73 || June 20 || @ Dodgers || L 4–0 || Kershaw (7–3) || Penny (5–6) || || 29,355 || 39–34 |- bgcolor="ffbbbb" | 74 || June 21 || @ Dodgers || L 6–1 || Billingsley (6–6) || Scherzer (9–3) || || 37,769 || 39–35 |- bgcolor="bbffbb" | 75 || June 22 || @ Dodgers || W 7–5 || Alburquerque (4–1)|| Lilly (5–7) || Valverde (17) || 30,332 || 40–35 |- bgcolor="ffbbbb" | 76 || June 24 || Diamondbacks || L 7–6 || Vásquez (1–1) || Purcey (1–1) || Putz (21)|| 37,335 ||40–36 |- bgcolor="bbffbb" | 77 || June 25 || Diamondbacks || W 6–0 || Verlander (10–3) || Collmenter (4–4) || || 43,163 || 41–36 |- bgcolor="bbffbb" | 78 || June 26 || Diamondbacks || W 8–3 || Alburquerque (5–1) || Heilman (4–1) || || 41,036 || 42–36 |- bgcolor="bbffbb" | 79 || June 27 || Blue Jays || W 4–2 || Benoit (2–3) || Rzepczynski (2–2) || Valverde (18) || 25,181 || 43–36 |- bgcolor="ffbbbb" | 80 || June 28 || Mets || L 14–3 || Dickey (4–7) || Porcello (6–6) || || 28,480 || 43–37 |- bgcolor="ffbbbb" | 81 || June 29 || Mets || L 16–9 || Capuano (7–7) || Coke (1–8) || || 26,338|| 43–38 |- bgcolor="bbffbb" | 82 || June 30 || Mets || W 5–2 || Verlander (11–3) ||