|| Maholm (0–3) || — || 11,118 || 8–9 |- style="background:#fbb;" | 18 || April 20 || @ Marlins || 0–6 || Nolasco (2–0) || Morton (2–1) || — || 10,112 || 8–10 |- style="background:#fbb;" | 19 || April 21 || @ Marlins || 5–9 || Volstad (1–1) || McDonald (0–2) || — || 12,308 || 8–11 |- style="background:#bbb;" | — || April 22 || Nationals || colspan=6 | Postponed |- style="background:#cfc;" | 20 || April 23 || Nationals || 7–2 || Karstens (2–0) || Hernandez (2–2) || — || 18,262 || 9–11 |- style="background:#fbb;" | 21 || April 24 || Nationals || 3–6 || Marquis (2–0) || Correia (3–2) || Storen (3) || 9,520 || 9–12 |- style="background:#cfc;" | 22 || April 25 || Nationals || 4–2 || Maholm (1–3) || Lannan (2–2) || Hanrahan (6) || 12,457 || 10–12 |- style="background:#fbb;" | 23 || April 26 || Giants || 2–3 (10) || Romo (1–0) || Hanrahan (0–1) || Wilson (6) || 9,832 || 10–13 |- style="background:#cfc;" | 24 || April 27 || Giants || 2–0 || McDonald (1–2) || Bumgarner (0–4) || Hanrahan (7) || 9,048 || 11–13 |- style="background:#fbb;" | 25 || April 28 || Giants || 2–5 || Vogelsong (1–0) || Karstens (2–1) || Wilson (7) || 14,747 || 11–14 |- style="background:#cfc;" | 26 || April 29 || @ Rockies || 3–0 || Correia (4–2) || Chacin (3–2) || Hanrahan (8) || 34,477 || 12–14 |- style="background:#fbb;" | 27 || April 30 || @ Rockies || 1–4 || Hammel (3–1) || Maholm (1–4) || Street (10) || 33,684 || 12–15 |- |- style="background:#cfc;" | 28 || May 1 || @ Rockies || 8–4 || Morton (3–1) || Jimenez (0–2) || — || 35,012 || 13–15 |- style="background:#cfc;" | 29 || May 2 || @ Padres || 4–3 || McDonald (2–2) || Harang (4–2) || Hanrahan (9) || 20,546 || 14–15 |- style="background:#fbb;" | 30 || May 3 || @ Padres || 5–6 || Adams (1–0) || Beimel (0–1) || Bell (7) || 18,636 || 14–16 |- style="background:#cfc;" | 31 || May 4 || @ Padres || 7–4 || Correia (5–2) || Richard (1–3) || — || 16,613 || 15–16 |- style="background:#fbb;" | 32 || May 6 || Astros || 2–3 || Rodriguez (2–3) || Resop (1–1) || Melancon (1) || 12,728 || 15–17 |- style="background:#cfc;" | 33 || May 7 || Astros || 6–1 || Morton