This application is a division of application Ser. No. 08/392,670, filed Mar. 23, 1995, now U.S. Pat. No. 5,593,851, which is a File Wrapper Continuation of Ser. No. 08/221,311 filed Apr. 1, 1994 now abandon. 
    
    
     The present invention relates to a test kit for use in the rapid diagnosis of gastric disease by the detection of Helicobacter pylori bacteria in a gastric biopsy specimen. The test kit includes means for handling a biopsy specimen and a test composition containing urea and a combination of dye indicators as described in my co-pending U.S. patent application, Ser. No. 08/195,954 filed Feb. 14, 1994; the entire disclosure of said application being incorporated herein by reference. 
     It has become well-established that (1) the bacteria Helicobacter pylori causes chronic active gastritis (see the annexed Bibliography for the numbered references), and that (2) virtually all patients suffering from duodenal ulcer and perhaps 80% of patients having gastric ulcers are infected by H. pylori. There is also epidemiological evidence that (3) correlates the presence of H. pylori with gastric cancer. In view of these facts, a test for the presence of H. pylori in a gastric biopsy specimen has become the preferred method for the diagnosis of gastric disease. 
     The purpose of the present invention is to provide an improved test kit for the rapid, convenient, reliable and accurate detection of H. pylori in gastric biopsy tissue. 
     BACKGROUND AND PRIOR ART 
     An extensive description of the background and prior art for the diagnosis of gastric disease by the detection of H. pylori in gastric tissue is set forth in my co-pending U.S. patent application Ser. No. 08/195,954 and is incorporated herein above by reference. 
     Briefly, it having been seen that the bacteria H. pylori is present in endoscopically obtained gastric biopsy specimens from both gastric and duodenal ulcer patients and it being known that the enzyme urease is always associated with that bacteria, the concept of diagnosing the presence of such ulcers by testing biopsy specimens for urease suggested itself. Chemical tests for urease were already known in the art. In one such test a urea-containing broth provides a positive urease reaction (hydrolysis of urea) as below: 
     
         urea+H.sub.2 O urease→NH.sub.3 +CO.sub.2 
    
     as indicated by a change in color of the indicator Bacto phenol red from yellow (pH 6.8) to red to cerise at pH 8.1 or more alkaline due to the production of ammonia an&amp;or ammonium carbonate by the urea-urease reaction. See the Difco Manual, 9th edition, Difco Laboratories, Detroit, Mich., (1953). The urea broth described in the Difco Manual was apparently used by B. J. Marshall in the work described in the Rapid Diagnosis of Campylobacteria associated with Gastritis, The Lancet, Jun. 22, 1985. 
     This type of urease test has come into commercial clinical use. In the United States a commercial test product is marketed under the trademark &#34;CLOtest®&#34;. This product is described in U.S. Pat. No. 4,748,113 issued to Barry J. Marshall on May 31, 1988. The test of the Marshall patent commercially employs urea, a buffer, a bactericide, arid phenol red as the dye indicator. This test is carded out in an alkaline pH range showing a positive result on a change of the indicator from yellow to red at a pH in the range from about 6.8 to 9. 
     In the Marshall test, a gastric mucosal biopsy specimen containing H. pylori is placed in solution or an aqueous agar gel containing urea, and indictor, phenol red, and buffers. The urease in H. pylori converts to urea to ammonia which raises the pH and turns the agar color from a yellow to red, indicating a positive test. According to the package insert in the Marshall commercial phenol red test (CLOtest®)it is recommended that the test be incubated at 30°-40° C for three hours and it is indicated that it may take up to 24 hours to develop a positive test. This test relies on the passive diffusion of urease from the cell wall of the bacterium into the agar gel testing solution. Moreover, operating as it does at a pH above 6.5, the test may give a positive result with bacteria other than H. pylori and thus is not entirely specific for Helicobacter pylori. Specifically, Proteus, Pseudomonas, and E. Coli species may cause a color change at this level and give a false positive test. 
     Another test kit for H. pylori is available commercially from Serim Research Corporation, 1000 Randolph St., Bldg. 17, c/o Miles Inc., Elkhart, Ind. 56515 under the trademark &#34;PyloriTek&#34;. This kit includes test strips having a substrate pad containing 3.3% urea and, in a separate matrix, a reaction pad containing 0.1% bromophenol blue dye indicator and 0.2% sulfamic acid. The test kit also contains, in a separate container, a hydration solution consisting of 1.8% Tris buffer. This kit, makes use of the same urease-urea reaction as the Marshall test to produce gaseous ammonia which changes the bromophenol blue from its original yellow color to make a blue test spot over a biopsy specimen on a yellow field to indicate a positive test. This test is said to be readable in 120 minutes and should not be read after that time to avoid false positives. While the two-hour usual test time is an improvement, it is apparent that an even more rapid and less complicated test would be desirable. 
     SUMMARY OF THE INVENTION 
     The present invention resides in the provision of a compact test kit for detecting H. pylori. in a gastric biopsy specimen which comprises a closed well or reaction vessel containing a gelled test composition, means for exposing the well, and means for introducing the biopsy specimen to the gelled test composition in the well. The kit may also be provided with means to record pertinent data as to the patient&#39;s identity and the time and date of the test. The kit may also include means to seal the well after use. The kit may also be provided with a color spectrum for determining the results of the test by comparison with the color change of a combination of dye indicators in the test composition. The test composition is disclosed in detail in my co-pending U.S. patent application Ser. No. 08/195,954 referred to above. 
    
    
     DETAILED DESCRIPTION OF THE INVENTION 
     The invention will now be described in greater detail in conjunction with the accompanying drawings, in which: 
     FIG. 1 is a top plan view of a preferred test kit; 
     FIG. 2 is a bottom plan view of the test kit of FIG. 1; 
     FIG. 3 is another bottom plan view of the test kit of FIGS. 1 and 2, showing a peelable label partially stripped away to uncover a gel-containing well in the test kit, and also showing the operation of means for removal of a biopsy pick from the test kit; 
     FIGS. 4 and 5 are detail drawings on an enlarged scale showing the means for removal of the biopsy pick from the test kit of FIGS. 1, 2 and 3; 
     FIG. 6 is a bottom plan view of the test kit of FIGS. 1-5 showing the use of the biopsy pick in placing a biopsy specimen in the gel in the test well; 
     FIG. 7 shows the use of the forked end of the biopsy pick in manipulating the biopsy specimen in the test well; and 
     FIG. 8 shows the peelable label resealing the well in the test kit after insertion of the biopsy specimen. 
    
    
     Referring now to the accompanying drawings, a preferred test kit of the invention 10 has a body member 12 including an upwardly open tray divided into two compartments 14 and 16 by a longitudinally extending upright partition wall 18. Two outer edges of the larger open compartment 14 are closed by upstanding walls 20 and 22. Upstanding partition 18 closes a third inner side of compartment 14, the fourth side of compartment 14 being open at 24. The larger compartment 14 of the tray in the test kit contains a well 26 integral with the base 30 of the compartment 14. The well 26 is open at 28 through base 30 of compartment 14 but is closed on its four sides and the bottom 32 which is upward in FIG. 1 and downward in FIG. 2. The well 26 is preferably transparent although it is only necessary that it be open at 28 to make its contents visible. 
     The well 26 is filled with a test composition 32 containing urea and a dye indictor which changes color when a gastric biopsy specimen containing Helicobacter pylori is placed in the well. The well 26 containing the test composition 32 is closed at its open side 28 by a peelable sealing means 34 which extends over an indentation 62 in the open end 24 of compartment 14. The peelable sealing means 34 is peelably adhered to the back of lower surface 30 of the compartment 14. 
     A means for handling a biopsy specimen is removably mounted in the second longitudinal compartment 16 which is upwardly and downwardly open as shown in FIGS. 1, 2 and 3. The means for handling the biopsy specimen is preferably a pick 36 having an elongated shaft 38 having a sharp point or bifurcated point 40 at one end and a forked 42 device at the other end including a sharp point 44 and a blunt prong 46. 
     The means for handling a biopsy specimen: such as the pick 36 is removably mounted in the compartment 16 by any suitable means such as by an adhesive or by a frangible integral molded joint. In the preferred embodiment shown in FIGS. 1, 2 and 3, the pick 36 is integrally but frangibly molded with a boss 48 which is firmly molded with or mounted on the wall 18 and extending into the compartment 16. The longitudinal compartment 16 containing the pick 36 has a deformable outer wall 50 which may optionally have a boss 52 extending into compartment 16 adjacent to or in contact with the pick 36. The pick 36 preferably has an enlargement 54 at the center of its shaft 38 intermediate the boss 48 and boss 52. The pick 36 is broken away from its frangible connection with boss 48 by deformation of the wall 50, by thumb pressure of the user or otherwise, to press the wall 50 inwardly to force the boss 52 into contact with the enlarged portion 54 of the pick to break it away from its frangible mounting on the boss 48. 
     An especially preferred embodiment of the means for mounting and demounting the pick is shown in FIGS. 4 and 5 in which the preferred configuration of the boss 48 extends outwardly from the inner wall 18 of the compartment 16 and has an upper planar side 56 and a lower slanting side 58 and a generally triangular cross section. The central enlarged portion 54 of the pick is frangibly connected to the under side of the lower slanting edge 58 of the flange 48. As the wall 50 is deformed inwardly by thumb pressure as shown in FIG. 3, the enlarged portion 54 of the pink is forced against the slanted surface 58 of the boss 48 until the connection is broken between the pick and flange and the pick is freed from its mounting. 
     Having freed the pick 36, it may be used as shown in FIGS. 7 and 8 to pick up the biopsy specimen by the point 40 as in FIG. 6 and to force it into the test composition 32 in the well 26. As shown in FIG. 7, the forked end 42 of the pick 36 may be used to position and firm the biopsy specimen in the test composition using either or both of the sharp point 44 or blunt prong 46 of the forked end of the pick. 
     FIG. 8 shows the use of the peelable sealing means 34 to re-seal the well 26 after insertion of the biopsy specimen. This peelable sealing means may also serve as a label to record the identity of the patient, the time and date of the test as shown in FIG. 8. 
     As shown in FIG. 1, the other side of the peelable sealing means 34 preferably carries a spectrum of colors and designations of the pH and negative (e.g. light green), slightly positive (e.g. medium green), moderately positive (e.g. dark green), and markedly positive responses (e.g. very dark green or blue), to this test. Other information and instructions may also be shown on this peelable label which can be read through the preferably transparent surface of the bottom wall 30 of compartment 14. 
     Other embodiments of the invention will be apparent from the preferred embodiments described above.
A molded pick for handling biopsy specimens which includes an elongated shaft having a tapered blunt short barb at one end and a forked device at the opposite end of the shaft, the forked device having a blunt spatula prong as one fork and a sharp tapered point as the other fork.