At the University of Houston, Guloy investigates the structural and physical properties of Zintl phases and intermetallic materials with a focus on transport properties and novel materials. He has been a professor of chemistry at the University of Houston since 1993 rising through the ranks to become the John and Rebecca Moores Professor at the University of Houston in 2015. In 1998 he was awarded an National Science Foundation CAREER Award. He was a visiting professor at Sun Yat-Sen University in 2015 and was awarded the Distinguished Visiting Scholar-Lecturer Award from Chungnam National University, Daejun, Korea in 2009.