The Amersfoort-born Coppens received his B.S. and Ph.D. degrees from the University of Amsterdam in 1954 and 1960, where he was supervised by Carolina MacGillavry. In 1968, following appointments at the Weizmann Institute and Brookhaven National Laboratory, he was appointed in the chemistry department at the State University of New York at Buffalo. He was a SUNY Distinguished Professor and holder of the Henry M. Woodburn Chair of Chemistry. Among the many 3-dimensional structures Coppens characterized is the nitroprusside ion.