text: High Resolution Melt (HRM) analysis is a powerful technique in molecular biology for the detection of mutations, polymorphisms and epigenetic differences in double-stranded DNA samples.  It was discovered and developed by Idaho Technology and the University of Utah. It has advantages over other genotyping technologies, namely:
  * It is cost-effective vs. other genotyping technologies such as sequencing and TaqMan SNP typing. This makes it ideal for large scale genotyping projects.
  * It is fast and powerful thus able to accurately genotype many samples rapidly.
  * It is simple.  With a good quality HRM assay, powerful genotyping can be performed by non-geneticists in any laboratory with access to an HRM capable real-time PCR machine.