text: The steady state approximation, occasionally called the stationary-state approximation or Bodensteins quasi-steady state approximation', involves setting the rate of change of a reaction intermediate in a reaction mechanism equal to zero so that the kinetic equations can be simplified by setting the rate of formation of the intermediate equal to the rate of its destruction.
  In practice it is sufficient that the rates of formation and destruction are approximately equal, which means that the net rate of variation of the concentration of the intermediate is small compared to the formation and destruction, and the concentration of the intermediate varies only slowly, similar to the reactants and products (see the equations and the green traces in the figures below).
  Its use facilitates the resolution of the differential equations that arise from rate equations, which lack an analytical solution for most mechanisms beyond the simplest ones. The steady state approximation is applied, for example, in Michaelis-Menten kinetics.
  As an example, the steady state approximation will be applied to two consecutive, irreversible, homogeneous first order reactions in a closed system. (For heterogeneous reactions, see reactions on surfaces.) This model corresponds, for example, to a series of nuclear decompositions like .
  If the rate constants for the following reaction are  and ; , combining the rate equations with a mass balance for the system yields three coupled differential equations: