text: Manganese-mediated couplings have been used for the synthesis of hydrocarbon natural products, such as pheromones. A synthesis of queen bee pheromone uses the intermolecular coupling of acetone and an ω-alkenyl acetate en route to the target.
  Lactonization is a key step in the synthesis of tomato pinworm sex pheromone. Subsequent Lindlar hydrogenation, reduction and acetylation provided the target compound.