text: Ionic compounds interact strongly with the solvent medium; therefore, their impact on chemical and biochemical processes involving ions can be significant. Even in the case of simplest ions and solvents, the presence of the former can lead to rearrangement and restructuring of the latter.  It is established that ionic reactions are involved in numerous phenomena at the scales of whole galaxies or single living cells. To name a few, in living cells, metal ions bind to metalloenzymes and other proteins therefore modulating their activity; ions are involved in the control of neuronal functioning during sleep – wakefulness cycles;  anomalous activity of ion channels results in the development of various disorders, such as Parkinsons and Alzheimers diseases,  etc. Thus, despite the problems associated with the studies on properties and activities of ions in various chemical and biological systems, this research field is among the most urgent ones.