text: Usually, in H fMRS the water signal is suppressed to detect metabolites with much lower concentration than water. Though, an unsuppressed water signal can be used to estimate functional changes in the relaxation time T2* during cortical activation.
  This approach has been proposed as an alternative to the BOLD fMRI technique and used to detect visual response to photic stimulation, motor activation by finger tapping and activations in language areas during speech processing. Recently functional real-time single-voxel proton spectroscopy (fSVPS) has been proposed as a technique for real-time neurofeedback studies in magnetic fields of 7 tesla (7 T) and above. This approach could have potential advantages over BOLD fMRI and is the subject of current research.