text: Prior to further mechanistic investigation, it is important to determine the kinetic dependence of the reaction of interest on the catalyst. The turnover frequency (TOF) of the catalyst can be expressed as the reaction rate normalized to the concentration of catalyst:
  :TOF = 
  This TOF is determined by running any two or more same-excess experiments in which the absolute catalyst concentration is varied. Because the catalyst concentration is constant over the course of the reaction, the resulting plots are normalized by an unchanging value. If the resulting plots overlay perfectly, then the reaction is, in fact, first-order in catalyst. If the reaction fails to overlay, higher-order processes are at work and require a more detailed analysis than described here. It is also worth noting that the normalization-overlay manipulation described here is only one approach for interpretation of the raw data. Equally valid results may be obtained by fitting the observed kinetic behavior to simulated rate laws.