text: The Framingham Heart Study and other epidemiological studies have found a correlation between lipoproteins and cardiovascular disease (CVD). Lipoproteins are generally a major target of study in lipidology since lipids are transported throughout the body in the form of lipoproteins.
  A class of lipids known as phospholipids help make up what is known as lipoproteins, and a type of lipoprotein is called high density lipoprotein (HDL). A high concentration of high density lipoproteins-cholesterols (HDL-C) have what is known as a vasoprotective effect on the body, a finding that correlates with an enhanced cardiovascular effect. There is also a correlation between those with diseases such as chronic kidney disease, coronary artery disease, or diabetes mellitus and the possibility of low vasoprotective effect from HDL.
  Another factor of CVD that is often overlooked involves the concentrations of low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL). These are often seen at higher than expected and necessary levels in the body due to food uptake, family history, and a person's metabolic rate. There is a correlation between these increased levels and stroke, heart attack, and mortality.