The standard free energy of the coil-to-globule transition of the uncharged polymer obtained from simulation Figure ) can be qualitatively compared with the experimental LCST data of uncharged ELP, as shown in Figure . The anion transients from a strongly hydrated (little polymer affinity) to a weakly hydrated (large polymer affinity) as the value of ε anion increases. Comparing to the charged polymer discussed later, only ionspecific effects can be observed both in the simulation and in the experiment.