The high affinity of the malaria parasite for glucose was also exploited in targeting the parasite by glucose derivatives, such as ferrocenyl carbohydrate conjugates . For example, compound K, disubstituted with acetyl-protected glucose moieties, showed moderate antimalarial activity in vitro in both Plasmodium falciparum chloroquine-resistant and non-resistant strains . Conjugates L (Figure ), derived from ferrocenyltriazole and carbohydrates, exhibited moderate to good cytotoxicity towards various cancer cell lines and antibacterial activity against both Gram-positive and Gramnegative pathogens . Significant cytotoxicity against various cancer cell line was also showed by triazole bridged ferrocene-selenoribose conjugate M[85] (Figure ) obtained via click chemistry.