Reliable prediction of unbinding kinetics through computational methods is an active field of research. As a result, there have been substantial efforts to construct benchmarks and comprehensively document computational workflows. A series of recent reviews detail the most significant advances in this field and highlight the emergence of two main trends for kinetics modeling: the use of structure-based descriptors of the bound pose and methods based on the explicit simulation of the unbinding process often using molecular dynamics (MD). In this work, we focus on explicit simulation which can be further classified into relative and absolute residence time methods.