Based on the fact that US irradiation can promote Ag2S to generate ROS (Fig. ) , the sonodynamic performance of the EH@Ag2S was further evaluated. To MHz, 50% duty free), the characteristic absorption peak of DPBF decreased significantly. Moreover, the variation of DPBF absorbance peak value at 424 nm relative to the initial value were recorded for different US irradiation time. As shown in Fig. and Fig. , the DPBF concentration of Ag2S group and EH@Ag2S group decreased with 60.9% and 53.9% after 6min, respectively. However, after prolonged US irradiation, the characteristic peak of H2O group decreased was not obvious (Fig. ). EH@Ag2S almost had no effect on the ROS generation ability of Ag2S, and followup experiments could be carried out.