The number of leads common to DW and ADV arbitrarily selected rectangles (DW+ADV leads) were 8 from DW22 (80-80.0% of the total number into the rectangles) and 3 from DW23 (37.5-42.8%). No leads from the DW25 group could be found predicting low values similar to the other 2 groups. The common DW+ADV leads were tabulated with their properties (Table ), their 2D structures drawn (Figure ), their complexes with 4dxd PyMol visualized (Figure ) and their corresponding amino acid surroundings at 4 Å identified by PyMol analysis of their complexes with FtsZ (Table ). As expected, the common DW+ADV ligands mapped to the PC190723 FtsZ idc binding cavity defined by the crystallographic 4dxd-PC190723 model (Figure and Figure ), except one of the DW22 branches that projected outside of the idc cavity (Figure ). PyMol visualization of the docked complexes predicted similar docking to a maximum of 26 amino acids expanding a segment between the 192 to 311 residues of FtsZ. Most of the identified amino acids predicted hydrophobic interactions of low specificity. However, higher numbers of the most specific hydrogen bonds than crystallographic PC190723 (4 hydrogen bonds) were predicted for the following leads, 1854 (6 hydrogen bonds), 1856 (6), 4811 (6) and 5762 (9) (Table ). According to all these analysis, the resulting top leader with higher possibilities to bind FtsZ was the 5762 ligand. Both the 5762 and the 4811 leads contained 2 primary amines and predicted a DW globularity of 0.31, lower than the 0.5 threshold proposed by the bacterial eNTRY rules (). Both properties may favor the penetrability of this no-benzamide leads to bacterial cell walls .