One of the downsides of LFIA is that it is less sensitive compared to PCR testing, especially with a small number of antigens during the early stages of the infection. Because of its low accuracy, health professionals often recommend test takers to test again with RT-PCR if found positive with the antigen test. This also means that a negative result does not eliminate the possibility of an infection. Finally, the LFAs are mostly qualitative or semiquantitative, meaning it does not display the amount of targeted antigens unlike the qPCR test.