To calculate the 95% CI and X% PI of the extrapolation while taking into account the uncertainty of each of the reaction rate coefficient estimation, a bootstrap algorithm was used. For each of the reactions, at the 6 different temperatures, a point was sampled from a Gaussian distribution centered on the logarithm of the reaction rate coefficient estimate (see Eq. 1), with the standard deviation equal to the standard error calculated in Eq. 2. The model associated with this reaction (Arrhenius or zero-barrier) was fit and the 95% CI and X% PI of this model were computed . This process was repeated 1,000 times and the 95% CI X% PI were taken as the average over the 1,000 samples of the 95% CI and X% PI boundaries. An example of the shape of the 95% CI and PI are shown in Fig. .