We validated our computationally-tractable version of E min by evaluating a test set of 197 chemical formulas. Our validation set is comprised of technologically-relevant molecules from three sources: molecules between 10 and 14 heavy atoms used to validate G4MP2 from Dandu et al., liquid organic hydrogen carrier (LOHC) molecules from Harb et al., and top redoxmers listed in a review by Li et al. We assess the quality of E min as a synthesizability predictor by measuring its ability to differentiate isomers from PubChem with the same stoichiometry from molecules generated by Surge. We compute for each chemical formula E min after computing the xTB en- confidence that E min will be reliable for even larger molecules than those we assess here.