Through sharing these observations, we hope to inspire future employment of DMET with standard and generalized density matrices as a diagnosis tool for thoroughly analyzing the entanglement between chromophore and solvent orbitals. Such analysis can potentially help researchers (i) identify solvent molecules to be explicitly included in the QM region, and (ii) develop empirical models beyond simple electrostatic or polarizable embedding to capture the orbital entanglement and charge transfer effects between chromophore and solvent molecules. These advances will be crucial for further improving the accuracy of TDDFT/MM excitation energies in complex environments.