These parameters gave a weight for the atoms used C,N,O,P,S,F of 2x for C,N,O than P,S,F. The weight of single-double, single-triple, and vice-versa were .4 any other mutation probability. The crossover and mutation rates are .9 and elite_fraction=.15 due primarily due to the complicated docking function, the interatomic interaction energy modeled by CCDC GOLD.