Fig. A schematic of the desorption-release process. The adsorbed species dissociates from the lipid membrane creating a freely diffusing species. These species are free to exit via the pore as released species. This mechanism is analogous to a 1 st order chemical reaction or one that is further combined as two consecutive reactions and the rate limiting step determines the apparent rate and whether the fall tie is a single of double exponential. The r des is the desorption rate of absorbed species. The r diff is the diffusion rate (i.e. flux) of freely diffusing species.