The electron diffraction (ED) experiments at 300 kV were performed using a ThermoFisher Titan microscope with a field emission gun. The microscope was operated in spot size 3, and the dose rate was tuned by adjusting the electron beam current using monochromator focus (gun lens) while keeping the exposure time and the illuminated sample area constant. The beam current was measured by capturing an image in 2k x 2k size having a pixel size of 22.23 Å without the sample (vacuum) using a Gatan OneView camera (4k x 4k px, pixel size: 15 µm, conversion efficiency @ 200 kV > 26.42 counts/primary e -) with an exposure time of 1 sec and then determining the average number of electron counts per pixel per sec. The dose rates were calculated by dividing average electron counts per sec by pixel area. Different dose rates, such as 0.33, 0.5, 1, and 2 e -Å -2 s -1, were used for the experiment, as shown in Table . The dose rate of 1 e - Å -2 s -1 was also validated by measuring the beam current of 0.050 nA illuminated over the sample having a beam diameter of 2 µm using a Faraday cup. The screening of the TEM sample to locate the ZIF-8 particles was done in imaging mode at 13.5 kx actual magnification with an exposure time of 40 µsec. The beam was blanked as soon as the particles were observed, and the microscope was switched to diffraction mode. Before acquiring the diffraction patterns, the sample was exposed to a cumulative dose of around 0.001 e - Å -2 . The exposure time and camera length were set to 1 sec and 1500 mm, respectively. The series of ED patterns were recorded at a constant dose rate until all the Bragg planes disappeared. The ED patterns of size 2k x 2k px were recorded from the camera's center region, with a pixel size of 0.0069 1/nm. All the ED experiments were repeated three times for better statistics.