In addition to the full VP proteoforms detected, the ZipChip platform was able to detect a variety of low abundant VP fragments in the serotypes analysed (Table ). Two types of fragments were identified: those resulting from N-terminus truncation and those resulting from C-terminus truncation. Peptides originating with their new respective N-terminal amino acids or ending with their new respective C-terminal amino acids were detected during peptide mapping to help confirm the presence of these detected fragments (AAV6 A204(Ac)-D590 / AAV8: G209-L738). Significantly more fragments were identified in the AAV9 serotype with two VP1 fragments (R116-L736 and L131-L736), a VP2 fragment (F173-L736), and five VP3 fragments (A204(Ac)-D657, A204(Ac)-S538, A204(Ac)-M518, A204(Ac)-N512, A204(Ac)-S448).