Table shows the time averaged enrichment of contacts between the peptides in the two different locations and each of the polymer species. The peptides have higher interactions with PEG in both locations. However, it is interesting to note that the peptides located in the core have a much higher tendency to interact with EO monomers than the peptides located at the core-shell interface. We attribute this to the amphiphilicity of EEK, resulting in its close proximity to the trapped water in the NP core. EO is hydrophilic, surrounding the water in the core is a peak in EO density (Figure (a)); EO is found around the water trapped in the core, resulting in a higher number of interactions between EEK and EO within the NP core.