In a second step we investigated the thermodynamics and kinetics of the chemical transformations involving the BLG/methanol interfaces under high-pressure conditions. We find pressure to stabilize functional groups on the BLG surface. We trace back such effect to an enhancement in interfacial hydrophobicity (i.e., an increase in the local concentration of hydrophobic groups) at increasing pressure. In agreement with experiments, 1,11 our simulations confirm the absence of local stability for C-C interlayer structures in the 0-10 GPa range.