) that the difference is not due to a change in the fast PT from the D, manifested in the early ps-time scales (Table for the extracted rates), but it results from a geminate proton recombination process from the peptide bridge happening on the nanosecond time scale (further discussion in SI section 8.4). Such differences in the D emission in water (D vs D-B-A configuration) highlight that even in water, the large ΔpKa * and the established PMF result in a PT across the peptide and not 'just' PT to water. In MeOH (Fig. ), we observed the excited-state deprotonation of the D for both (EA)4 and (A)8 peptides in their D-B-A configuration (Fig. and 3g, respectively), while the (EA)4 peptide showed the deprotonation of the D even in the absence of the A (Fig. ). In CHCl3 (Fig. -l), we have observed such deprotonation only for the (EA)4 bridge and only for the D-B-A configuration (Fig. ).