Nanoparticle albumin-bound technology (Nab-technology) is an innovative method for the encapsulation of hydrophobic drug into albumin NPs. The first nanoparticle-based product approved and marketed was produced by nab-technology. During this process, hydrophobic drug is dissolved in an organic solvent and that is emulsified in albumin aqueous solution. This primary oil in water emulsion is then processed by high-pressure homogenization, leading to the albumin self-crosslinking and the formation of albumin layer around the drug core. The final step is solvent is evaporated which results in the formation of NPs.