Interestingly, when compared across different solvents, the coupling constants of a given molecule are indeed rather constant. Notably, the corresponding peak patterns often vary substantially due to the impact of non-first order effects. While the impact of conformational changes in conformationally more flexible systems has to be acknowledged, J couplings generally show constant behavior as their name implies, which, for all practical purposes, makes them important focal points in the interpretation of HNMR spectra. Similarly, the observed chemical shifts of identical or analogous hydrogens in HNMR spectra is often highly variable, thereby also fitting the designation as being a shifting entity.