The domains involved in transport are: Bmp domain (Interpro entry: IPR003760, PFAM: PF02608) is a basic membrane lipoprotein and also a substrate-binding protein of ABC transporter. Examples include PnrA (also known as TmpC or TP0319) and RfuA (also known as Tpn38 or TP0298) from Treponema pallidum. PnrA transports purine nucleosides , while RfuA transports riboflavin . CBIO (Interpro entry: IPR005876) is the cobalt transporter ATP binding subunit . CitMHS domain (Interpro entry: PF16980) is citric acid salt transporter family belongs to the NhaD-like permease superfamily of Na+/H+ antiporters. The DctM domain (Interpro entry: IPR010656) is the DctM subunit of the TRAP C4-dicarboxylate transport system permease. The C4-dicarboxylate transport system can absorb C4-dicarboxylates such as succinate, fumarate, and malic acid . DctM is a complete membrane protein and one component of the periplasmic TRAP vector . DUF3382 (PFAM: PF02653) is a high-affinity permease for the branched-chain amino acid transport system . DUF3708 (PFAM: PF00528, Interpro entry: IPR035906) is the D-methionine transport system permease protein MetI, the helix subset, observed in the larger transmembrane subunits of the molybdate (ModBC) and maltose (MalFGK) ABC transporters . FtsX (Interpro entry: IPR003838, PFAM: PF02687) is an ABC3 transporter permease protein domain. It is a heme transport system. The permease protein HrtB may be part of the ABC transporter complex involved in the import of Hemin . It is also the transmembrane protein LolC of the lipoprotein release system . FtsX_ECD (Interpro entry: IPR040690) is the extracellular domain (ECD) found in FtsX, which is a homolog of transmembrane PG hydrolase modulator . HMA (Interpro entry:IPR006121) is a conserved domain found in many heavy metal transport or detoxification proteins . MacB_PCD (Interpro entry: IPR025857) is a periplasmic core domain found in various ABC transporters, similar to AcrB multidrug efflux transporters . MatC_N (Interpro entry: IPR009827) is the N-terminal region of the dicarboxylate carrier protein MatC 100 . MatC protein is a complete membrane protein that can be used as a malonate carrier. MFS (Interpro entry: IPR011701) targets a wide spectrum of substrates, including ions, carbohydrates 101 , lipids, amino acids and peptides, nucleosides and other small molecules in both directions across the membrane 102 . The NIL domain (Interpro entry: IPR018449) is at the C-terminus of the ABC transporter involved in D-methionine transport and many ferredoxin-like proteins. The NMT1/THI5 series (Interpro entry: IPR027939) are the substrate-binding components of the ABC transporters of vitamins B1 and B2 103 . OppC_N domain (Interpro entry: IPR025966) is the N-terminal domain of oligopeptide transport permease C-like . OpuAC (Interpro entry: IPR007210, PFAM: PF04069) is the ABC-type glycine betaine transport system 104 . PBPb (Interpro entry: IPR001638, SMART: SM00062) is the 3/N-terminal domain of the MltF solute-binding protein family . The PDGLE domain (Interpro entry: IPR025937) was also found in the energy coupling factor transporter substrate capture protein NikMN, indicating that it may play a role in metal transport. Peripla_BP_4 (Interpro entry: IPR025997, PFAM: PF13407) participates in the active transport of galactose 106 , AI-2 107 , and acidic amino acids 108 across the plasma membrane of the solute. Peripla_BP_6 (Interpro entry: IPR028081, PFAM: PF13458) is a leucine binding protein and Leu / Ile/Val binding protein, the main receptor of the leucine transport system 109 . SBP_bac_5 (Interpro entry: IPR000914) is involved in the active transport of solutes across the plasma membrane 110 . The SSD domain (Interpro entry: IPR000731) is a sterol sensing domain . The STAS domain (Interpro entry: IPR002645) is found in the C-terminal region of the bacterial anti-sigma factor antagonist (ASA) and SLC26 (sulfate) anion transporter . ABC_transpr_TagH (Interpro entry: IPR015860) participates in the export of teichoic acid 112 . The TOBE_2 domain (Interpro entry: IPR013611, PFAM: PF08402) is related to the transport of molybdenum (SWISSPROT: P46930) and sulfate (SWISSPROT: P16676) .