The data were processed in Topspin, and the spectra were subsequently fitted in MATLAB. As in ssNake : the spectra were fitted with Gaussian and Lorentzian broadened line shapes to best fit the spectra (Section S1). The integrals, chemical shift, and Gaussian broadening were the parameters being fitted whilst the Lorentzian broadening was fixed to 1000 Hz. The C=C integral values included the intensity from the spinning sidebands.