The online catalogue of Molport (www.molport.com) was screened for analogues of the XChem hits 20 and 21 using similarity and substructure searches. To merge hits 20 and 21, the Molport database was screened for benzoic acids that could form interactions with FabF as found for hit 20 and 21 and their analogues. SD files of the hits were downloaded and prepared for docking using LigPrep from Schrodinger (Schrödinger, LLC, New York, NY, 2019. . Crystal structures of PaFabF-C164Q in complex with each hit were loaded into Maestro (Schrodinger) and prepared for virtual screening using ProtPrep. Subsequently, the prepared structures were loaded into SeeSAR (BiosolveIT) for docking. The active site was defined using the hit compounds as guidance and the crystallographically determined binding mode of each hit was used as a template during docking. High scoring compounds that had similar binding modes to the hit compounds and that that formed additional interactions in the binding site were short-listed for purchase.