Clustering was carried out using the average linkage , obtaining two populated clusters, one with 461732 members (from now on cluster 1), and another with 101971 members (cluster 2), whose centroids will be the two structures of the SARS-CoV-2 RBD on which the docking with Qvina will be carried out. Thus, the workflow for virtual screening in several stages from docking with QVina will be carried out 4 times: FDA database on cluster 1, FDA database on cluster 2, NAT database on cluster 1 and NAT database on cluster 2.