Unlike the SARS-COV-2 virus, the Ebola virus has an extremely high need for potassium during reproduction and dissemination. This present study discovered that LCN type CS-α/β of L, N, VP24, and VP35 can interfere with K + channels. It prevented intracellular K + from being recycled into the blood and bodily fluids via the K + channel. Eventually, a cell would develop an environment with elevated sodium, calcium, and potassium levels. Ebola patients' blood sodium, calcium, and potassium levels were lower than usual, resulting in hyponatremia, hypocalcemia, and hypokalemia.