Molecular organization in biological systems dynamically stays away-fromequilibrium. The maintenance of the non-equilibrium state often relies on continuous consumption of high energy molecules such as ATP harvested from metabolic reaction networks. This has encouraged the construction of synthetic analogue of nonequilibrium molecular assemblies. In the last few decades, a series of non-equilibrium molecular assembly has been constructed driven by elaborately designed chemically fueled activation/deactivation reaction cycles . These reaction cycles function as simplified model of anabolism and catabolism to drive the formation of nonequilibrium assemblies to recapitulate the non-equilibrium state of living organization .