The second experimental scenario concerns plasmon-assisted isomerization of a photochromic component in the AzoGly-Au-1-CNFs hybrid material. For this purpose we designed an OFF-ON experiment by subjecting composite to the consecutive intervals of dark and light conditions during individual measurement. This minimized the possibility of systematic errors, accounted for random deviations stemming form high Au-loading, and facilitated the depiction of material's susceptibility towards light. Conditions were identical through the whole experiment and the only difference was either presence or lack of irradiation and triggered plasmon-related effects. Thus, we propose an experimental design based on real-time analytics aided by advanced statistical modelling.