In summary, we introduced OSCFF, a GAFF2-compatible force field for OSCs that supports a wide range of torsion types in conjugated molecules and enables accurate RESP charge prediction via E3NN. This is realized based on training two extensive molecular datasets: one containing approximately 56,000 fragment geometries with torsion profiles, and another comprising around 472,000 optimized molecular geometries with RESP charges. The OSCFF has exhibited exceptional accuracy in predicting torsional energy profiles, RESP charges, 13 and the radial distribution function (RDF). Furthermore, we also provide a pipeline to streamline the process of initializing MD simulation systems. We expected that OSCFF will be a valuable tool for OSCs design and research, particularly in exploring bulk properties like molecular arrangement and electron mobility through MD simulations and multi-scale simulation.