Copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC) was used to prepare a series of uracilferrocene conjugates like D as potential antitubercular agents . The same type of reaction afforded compound E, exerting potent cytotoxic effect on cancer cells , and derivative F, a ferrocene -L-alanine ester -uracil conjugate exhibiting weak antifungal activity against the yeast strain of Candida guilliermondii (IBA 155) . The versatility of click reactions was also verified by the obtainment of bisferrocene conjugates G bridged by 1,2,3-triazole linkers to 5-substituted uracil, showing pronounced and selective cytostatic activities on various cancer cells with mitochondria as molecular target .