Metal-organic, or coordination, cages (MOCs) 1 are generally prepared from single metal ions/nodes and single, high-symmetry ligands. This simple recipe has yielded cages of varying size, nuclearity and geometry, and their use in catalysis, 2 stabilisation of reactive species, 3 molecular separations 4 and encapsulation of anions 5 and pollutants, 6 amongst others. More structurally sophisticated, reduced symmetry architectures, 7 however, offer the potential for precision engineering of MOC hosts. As such, there has been increasing interest in targeting lowsymmetry MOCs.