In this study, we have introduced and evaluated two distinct methodologies for sampling the nuclear degrees of freedom in a system governed primarily by non-bonded interactions: a liquid mixture of phenol and carbon tetrachloride. Our aim was to determine which protocol provides a more reliable description of the aggregate populations. Subsequently, we assess their performance by comparing the average IR spectra, computed with the populations resulting from each methodology, against the experimental one at varying concentrations, particularly focusing on the OH stretching region.