The trends of all the samples are similar, showing changes in the quality of the samples over time. The TGA analysis reveals three distinct sample weight loss stages, which agree with previous reports. In low-temperature regions (T < 200 °C), the reduction in the sample mass is due to the loss of water and other molecules through evaporation. The molecular formula of HKUST-1 MOF is assumed to be Cu3(BTC)2(H2O)3, with the number of crystal-bond water groups x ~ 3.0. In the T = 200 -300°C range, the sample did not experience any significant mass change, confirming the framework's thermal stability at higher temperatures. A sharp decrease in weight (about 27.5 wt.%) at T ~ 340°C is caused by the decomposition of the BTC linker. It is worth mentioning that HKUST-1@150°C displayed slightly improved thermal stability compared to the other samples. This can be attributed to its superior crystal structure compared to the other samples. Comparing the efficacy of MOF synthesis methods can be challenging due to several factors, such as the compositions of precursors and varying molar ratios used across methods. Furthermore, the measurement techniques can impact the characterization of morphology parameters, including particle size, uniformity, and surface area. Historically, reaction time, space-time yield (STY), and surface area production rate (SAPR) have been employed to evaluate the scalability of synthesis analysis. Though not perfect, these metrics offer a means to assess the relationship between the production rate and the material quality. Figure In summary, we reported a study focused on identifying the properties of HKUST-1 based on the synthesis condition. Previously Rasmussen et al. showed that in the constant temperature scCO2 reactor with a residence time of ~ 100 sec, the properties of synthesized HKUST-1 did not vary significantly once the scCO2 conditions for the mixture were met. In a reactor with a shorter residence time, the temperature non-uniformity in the reactor is inevitable. It is the result of mixing room temperature reagents and the hotter scCO2. Before complete mixing occurs, the reagents could be exposed to scCO2 injection temperature (Tinj = 50°C -350°C), causing partial degradation of the MOFs.