To probe the reactivity of borohydride reagents relative to that of other chemical reductants, a selection of compounds was assessed with cyclic voltammetry (CV). As evident from Figure , the sacrificial anode materials Zn and Mg displayed the lowest oxidative onset potentials of around -0.6 and -0.2 V vs Fc +/0 , respectively. Closely following these values, the oxidative onset potential of NBu 4 BH 4 was determined to -0.1 V versus Fc +/0 , whereas all organic reductants were oxidized at considerably more positive potentials. These measurements were carried out in a THF electrolyte (0.1 M TBAPF 6 ) (see ESI, section S3) and it should be noted that redox potentials can be highly condition-dependent. Nevertheless, the trend from these measurements clearly demonstrates the potential of borohydrides as anodic fuel to replace sacrificial metal anodes in net reductive electrochemical transformations. Provided that chemical compatibility of borohydride reagents and starting materials is at hand, their low oxidative onset potential suggests that they would be more efficient in suppressing unwanted oxidative transformations compared to other common chemical reductants such as amines, thioureas and phosphines.