is required to reach a benchmark-quality result, with a DLPNO error of only 0.5 kcal/mol or < 1% of ∆E. The (L/N) MP2 extrapolation scheme might be considered acceptable for (C 54 H 18 ) 2 . Unfortunately, this consideration depends on system size and therefore it seems unwise to make a blanket recommendation for all systems. Results for (C 96 H 24 ) 2 suggest that (N/T) MP2 extrapolation (i.e., the N/T procedure using MP2 thresholds) is a viable option for benchmark-quality results on nanoscale dispersion-bound complexes with more than 100 atoms. Absent extrapolation, however, the DLPNO results are clearly unacceptable as benchmarks in systems of this size.