Photoinduced singlet oxygen ( 1 O2) generation is an intrinsic property of many dyes, including BODIPYs. Simultaneous production of 1 O2 and NO is of interest for the development of hybrid photodynamic therapy . The iodinated derivatives BODIPY-NOD-3 and BODIPY-NOD-5 are promising in this respect. The normalized absorption spectra and photophysical properties of iodinated compounds are shown in the Figure . Absorption spectra are red-shifted shifted by ~30 nm for the diiodinesubstituted BODIPY compounds due to its electron-acceptor nature, in accordance with previously published data on similar compounds. Fluorescence for these compounds are weak (QYs are 0.015 and 0.003, respectively), probably due to the enhanced conversion into triplet state. Interestingly, BODIPY-NOD-3 is also capable of NO photorelease, as shown in Figure . Despite relatively low speed and total yield (cf. Figure ), it could greatly enhance the action of 1 O2 as photodynamic agent. In contrast, the release of NO is not detected for BODIPY-NOD-5.