1.1 1 st LLM Speed Advantage Figure : Cell culture process scale up example, Zhang, S., et al. 2024 Search methods ChatGPT-4o Search "ChatGPT-4oS", Perplexity GPT-4o "PGPT-4o", Perplexity 3.5 Sonnet "P3.5Sonnet", and Claude Computer Use 3.5 Sonnet "Cu3.5Sonnet" were each provided a mAb kinetics search problem to solve in triplicates. The LLM multiplier speed formula used was: (LLM words/Human words)*(Human Time/LLM time). Each of the generations were run in regards to Protocol 1 in Table to identify recent mAb production advancements compared to the manuscript author. Results are available in Table , and full generations are available in Supplementary SSA.