In this study, we present a method for straigh�orward control of LC alignment in 3D by employing polydimethylsiloxane (PDMS) microscaffolds using a commercially available two-photon 3D laser prin�ng set-up. It has been reported that the hydrophobic proper�es of PDMS surfaces induce a perpendicular anchoring effect of LC molecules . However, the fabrica�on of PDMS scaffolds has been limited to conven�onal molding method, using a PDMS-based master mold or microfluidics to manipulate LC orienta�ons , where the geometries and resolu�ons were very limited.