The synthesis route for the total synthesis of micitide 982 (1) begins with 2-bromo-4-iodoaniline (5) (Scheme 1). After protecting 2-bromo-4-iodoaniline ( ) with an Ac group, boronic acid 16 was obtained on a decagram scale through Miyaura borylation followed by pinacol deprotection. Compound 16 was then subjected to a Suzuki coupling with compound 6 to synthesize biaryl 17. The resulting biaryl 17 was adjusted on a decagram scale to obtain aryl iodide 18, a precursor for C-H biarylation, through Boc deprotection and subsequent Sandmeyer reaction.