Fig. shows the low magnification 300 kV TEM image of multiple ZIF-8 particles supported on holey amorphous carbon using a low dose rate condition of 1 e -Å -2 s -1 . The particle size ranges from 150 nm to 230 nm, with an average size of 180 nm. The left inset in fig. shows the HRTEM image of a single ZIF-8 particle acquired at a dose rate of 5.2 e -Å -2 s -1 , with an exposure time of 3 sec and a total accumulated dose during image acquisition of about 15.6 e -Å -2 . The right inset in fig. shows the power spectrum from the lattice image of ZIF-8 particle, oriented along [111] direction. The {110} and {211} Bragg planes are resolved. Fig. shows the ring electron diffraction pattern of several ZIF-8 particles recorded with an electron dose rate of 1 e -Å -2 s -1 and an exposure time of 1 sec. Details about estimating the applied electron dose rate are described in the Methods section. The highest spatial frequency obtained from the diffraction pattern is 7 nm -1 marked with a green circle in fig. ) corresponds to a spatial resolution of ~1.4 Å. The Bragg planes with increasing spatial frequency are marked with red dotted circles in fig. (b) as follows: {110}, {200}, {211}, {222}, {400}, and {431}. We have also observed the same trend in the loss of crystallinity of ZIF-8 as reported in , from the fading of the intensity of Bragg planes, as shown in fig. ).