The majority of molecules active against PqsR have the highest DataWarrior complexity and some of them show pIC50 upper than 7. In contrast, RhlR compounds are concentrated in the lower left of figure , where molecules with low activity and poor complexity are showed. Finally, LasR active compounds could not be associated with specific complexity values because this dataset has a high molecular diversity as are evidenced in posterior analysis. Antagonist molecules in all datasets don't have a clear behavior associated with complexity in metrics studied.