The high-pressure limit for the reverse dissociation rate constants have a strong sensitivity to reaction enthalpies, as do the pressure-dependent rate constants in both directions. Thus, it is desirable to obtain high accuracy estimates for the reaction enthalpies. To this end, we used the connectivity-based hierarchy (CBH) technique for systematically constructing error-cancelling reaction schemes in conjunction with the laddered CBH-ANL approach. The first (CBH0), second (CBH1), third (CBH2), and fourth (CBH3) rungs of the CBH schemes have been used in this work. These reactions would fall under the "isogyric", "isodesmic", "hypohomodesmotic"/"isoatomic", and "hyperhomodesmotic" reaction classes respectively, in the hierarchy put forth by Wheeler et al. As shown in the Supporting Information, CBH0 was used for the target species CF 3 , CBH2 for C 2 F 5 and C 2 F 6 , and CBH3 for C 3 F 7 , C 3 F 8 and C 4 F 10 . The required reference species for these schemes have also been considered as shown in Table . A laddering scheme of successive quantum chemistry methods was used to construct the different CBH level references. CBH0 reference species for each element in consideration (H, C, and F) were selected as H 2 , CH 4 , and HF, for which enthalpies of formation at 0 K were sourced from the Active Thermochemical Tables (ATcT), V1.202. We also used ATcT values for H to define a reference radical enthalpy of formation.