In simulations of the 4w57-butylbenzene system, we find a process that occurs above the lag time (Figure ). However, this process is an exchange within the oval-shaped well of the 2D TICA surface which we do not believe is kinetically meaningful. Interestingly, the second slowest motion of the 4w57-butylbenzene system corresponds to changes in density between the bridge and oval-shaped regions of the TICA space (Figure ) -which we believe correspond to the closed and intermediate states, respectively (Figure ). However, this process decays faster than the MSM lag time and thus we do not consider the intermediate state to be a discrete state based on analysis of this system (Figure ).