Cholesterol is transported by low-density lipoprotein cholesterol (LDL-c) and high-density lipoprotein cholesterol (HDL-c), abnormal serum level of LDL-c and HDL-c is associated with breast cancer and its normal serum level is considered as prognostic marker for breast tumor . In this study, exposure of rats to carcinogen elevated serum cholesterol, triacylglycerols, LDL-cholesterol and HDL-cholesterol levels. S. alata extract in a dose dependent manner significantly decreased the higher levels compared to the control.