Our novel Monte Carlo method is a logical descendant of another Monte Carlo sampling method called Smart Darting Monte Carlo. The general process of Smart Darting involves defining two key pieces of information. The first piece we need to specify is a set of "darts", which represent different configurations of the system that are of interest. The second piece we need to specify is a set of parameters (and their ranges), which correspond to and define each of those darts, in order to specify the boundaries associated with each conformation.