or Nudged Elastic Band (NEB) algorithms. More automated reaction pathway exploration algorithms include double-ended path optimization which starts from reactants and products, and single-ended searching by moving along a reaction coordinate. For more details on reaction pathway explorations, please refer to ref . Gastegger and Schreiner mentioned in their papers that the inclusion of stationary points and optimized reaction pathways can efficiently improve the quality of RMLPs. However, these methods are highly computationally demanding due to expensive QM-level optimization and frequency calculations. Additionally, They usually do not enough off-equilibrium structures and may require prior knowledge of reaction mechanisms. In this section, we organized commonly applied techniques for data sampling, augmentation, refinement with affordable cost and strategies for comprehensively learning reactive potentials.