Improving water quality by reducing pollution is also defined as one of the tasks in the Sustainable Development Goals . Meanwhile, the number of known chemicals that are in use is increasing dramatically. Over 350,000 chemicals and mixtures have been registered in the global market over the past 50 years , while the largest chemical databases contain over 100 million chemicals, with PubChem and the Chemical Abstracts Service (CAS) registry containing 116 million and 219 million [6] chemicals, respectively, as of January 2023. Chemical production and pollution are outpacing global assessment capacity, posing more risks to human health, wildlife, and the environment . In 2021, about 224.8 and 86.4 million tonnes of chemicals hazardous to human health and the environment, respectively, were consumed in the European Union (EU) . Some of these chemicals are persistent, mobile and toxic (PMT) substances or very persistent and very mobile (vPvM) substances, collectively referred to as PMT/vPvM substances.