The generation length limit were evaluated using the recently published metal-free C-N cross coupling procedure. This method, including 9 reagent additions, 4 temperature changes and 3 reaction time settings, transcript to a total of 18 iControl operations (including stir and end operations). Depending on the operation type, the token usage of one additional operation is 100 to 240. All solid reagents in this procedure were given in moles or equivalence, which may increase token usage during calculation steps in the first output. Assuming no additional prompt was used other than the base example, the resulting XML with the structured prompt would result in an estimated usage of 5140 tokens, which is beyond the ~4,000 limits in recent GPT models. This means that lengthy protocols need to be broken down into smaller portions, which could impact reliability of the translation. In 10 conversations during late April to June, 2024, we observed a higher occasion of multiple missing steps or unfinished scripting. For cases where operations or chemical elements are missing, the fix rate is promising when prompting for full procedure or full chemical Fig. Online HPLC monitoring of 1-methylpiperazine and 1-methyl-4-(4nitrophenyl)piperazine. ). Due to the token limit, the maximum length of procedure is ideally within ~120 words or 15 steps.