Concept combining a high-tech, or cutting-edge, technological research and development, with a simple, low-tech implementation. Low-tech implies simpler technologies requiring minimal tools or techniques. Self-microfabrication requires a complex development (e.g. studying organogenesis) but may eventually offer a simpler implementation by leveraging self-organization (e.g. planting a seed). Single-cell and multi-omics techniques Techniques integrating multiple types of molecular data at the single-cell resolution (such as genomics, transcriptomics, proteomics, and metabolomics).