While the absolute difference in driving pressure between baseline and clog ablation (∆P Abl -∆P 0 ) and the frequency of ablation f do not vary significantly with Q T , it is worth considering that Q T controls both the baseline driving pressure and the baseline wall shear rate. Thus, the normalized pressure at ablation ∆P Abl /∆P 0 is lower at 12 µL/min than at 1.2 µL/min: ∆P Abl /∆P 0 ∼ 162% at low flow rate, decreasing to 109% at high flow rate. Similarly, when the frequency of ablation is normalized by baseline wall shear rate, before ablation, this normalized frequency decreases with Q T . The baseline wall shear rate is estimated using γ = 4Q/πR 3 0 , where R 0 is the measured hydraulic diameter for a clean device. The inset in Fig. shows the decrease in f = f / γ. The dotted line indicates a power law dependence f ∼ Q -n T , where the exponent n = 0.6. Other parameters also influence intermittent behavior, some in surprising ways. For instance, without sodium chloride present in the alginate stream, no deposition is seen (SI Fig. ). On the bulk scale, sodium chloride is not necessary to induce alginate gelation in the presence of calcium . However, not only is NaCl required for in-channel deposition, but its effect on deposition behavior is non-monotonic. As C N aCl increases relative to C Alg , the observed peaks in ∆P (t) decrease in magnitude, approaching the baseline condition which occurs in the absence of sodium. Deposition also depends on surface chemistry. Observed peaks in ∆P (t) are smaller when alginate and calcium mix in a channel with a hydrophilic coating than in a hydrophobically coated channel (SI Fig. ).