Magnetic nanoparticles can be synthesized via several procedures including laser techniques . Abdelhamid reviewed the application of delafossite nanoparticles in energy, nanomedicine, and environmental applications . Magnetic nanoparticles of Fe3O4 were incorporated into polyplexes of CPPs/oligonucleotides (ONs) for cell transfection . Three different oligonucleotides (e.g., plasmid (pGL3), splicing correcting oligonucleotides (SCO), and small interfering RNA (siRNA)) and six CPPs (e.g. PeptFect220 (denoted PF220), PF221, PF222, PF223, PF224, and PF14) were investigated. Magnetic nanoparticles enhanced the cell transfection up to 4-fold compared to the noncovalent PF14-SCO complex, which exhibited higher efficiency compared to a commercial vector called Lipofectamine™2000 .