The results obtained here come as a result of report and manuscript developments across seven author studies. The ability of LLMs and LMMs to effectively answer drug synthesis questions was realized in July 2024 . The effectiveness of using document retrieval on Organic Syntheses, JACS, and Nature Communications papers to answer challenging synthetic chemistry questions was also confirmed by generative AI models in the same year . Additional utility regarding high dimensional and complex spectroscopic images and text data of chemicals and drug compounds was also achieved by generative AI models later in 2024 . 9 Limitations and Future Work "The prerequisite for plant natural product production in microbial hosts is a complete understanding of the biosynthetic pathway. To date, despite extensive investigation over the past two decades, the full biosynthetic route to paclitaxel has not been elucidated." Chun-Ting Liu, J., et al. 2024 .