To better understand polythioamides, samples with higher degrees (above 50 %) of thionation were targeted. However, during the purification stage, solubility issues were observed, particularly after the first precipitation. HFIP was the only solvent suitable for dissolving highly thionated samples, but further purification and characterization were not conducted. The primary reason was that the process required dialysis, which would be difficult using HFIP as the dialysate.