We used an open-source Matlab script provided by the Vibrational Spectroscopy Core Facility at Umeå University to process Raman spectra . To baseline correct the spectra we used an asymmetrical least-squares algorithm 28 with = 10 4 and p = 10 -3 . We smoothed spectra using a Savitzky-Golay filter of polynomial order 1 and a frame rate of 5. Graphs were plotted in Origin 2018 (OriginLab).