CAR is an anticonvulsant drug, primarily used for the treatment of neuropathic pain and epilepsy . Based on the calculated Ra, CAR compatibility with the four different hydrophobic blocks was in the following order i.e. pBuOzi > pPrOzi ≈ pPentOx > pBuOx (Figure ). The experimentally determined solubility of CAR was found to be 0.005 g/L (Table ). At 2 g/L CAR feed, no significant difference in solubility (≈ 0.7 g/L) (LC ≈ 6.5 wt.% and LE ≈ 35%) was observed for all four triblock copolymers (Figure ). However with the further increase in CAR feed, slight improvement in solubilizing capacity of A-pPrOzi-A (≈ 1.5