Note that Eq.( ) is general and remains valid for any enzymatic mechanism since it stems only from (i) the diffusional supply of the substrate 𝑆 to the enzymatic layer and (ii) the electroactivity of the product 𝑃 at the electrode electroactive surface, both processes occurring in the enzyme-free sections of the electrochemical enzymatic sensor. Conversely, the very nature of the mechanism active in the thin enzyme coating is only acting through the exact analytical dependence of 𝑟𝑎𝑡𝑒 on [𝑆] whose value is related to [𝑆] and to the current intensity through Eq.( ).