NAPROC-13 includes information on deuterated solvents utilized for solubilizing each compound during in the Supporting Information, respectively. In Figure , it is remarkable the differential distribution of properties among the categories of analysis solvent (approximable to solubility) included in NAPROC-13. Solubility is a macroscopic property of molecules in the presence of third substances, commonly associated with physicochemical/constitutional molecular properties, similar to the melting and boiling points. Some of the striking differences in this respect are related to the polarity and possibility of interacting through hydrogen bonds of molecules, and to the polar/non-polar character of the solvent. To name, some of these interesting relationships are the differential distribution of HBD and HBA, the number of heteroatoms, and CSP3.