"Membrane receptor other" and "Transferases", as well in the chemical classes "Glycerophospholipids" and "Glycerolipids", while the numbers of cells with increased counts have been largest in "7TM1", "Hydrolase", "Enzyme other", and "Other" target classes, and in the "Organoheterocyclic compounds" and "Benzenoids" chemical classes. The target classes with the largest increases in total counts of interactions correspond to "7TM1" again and "Oxidoreductase", while "Fatty Acyls", "Organic acids and derivatives" and "Benzenoids" are the chemical classes with largest increases in total counts. By considering the bacterial targets (Figure ), 50 previously empty cells have now been filled with one or more interactions, and 96 cells have increased their counts. The target classes with the most effective filling of empty cells are "Enzyme other", "Phosphodiesterase", and "Other", while the chemical classes are "Glycerophospholipids", "Benzenoids", and "Organic oxygen compounds". The target classes with largest numbers of cells with increased counts are "Enzyme other", "Other", and "Protease", while the chemical classes are "Benzenoids" and "Phenylpropanoids and polyketides". Finally, the largest increments in total counts have occurred in the "Enzyme other" and "Other" target classes, and in the "Organic acids and derivatives", "Fatty Acyls", and "Benzenoids" chemical classes.