Then, we explain why the typical size of stable bulk nanobubbles reported is often around 100nm. We propose that for most experimentally reported bulk nanobubbles that are stabilized by the adsorption of trace organic contaminants, the multicomponent nature of the monolayer leads to a very low bending constant 𝜅 due to the effect of chain disorder. At such a small 𝜅 , the thermal fluctuation is of a comparable contribution as the bending energy. Under conditions of 𝜅~ 𝑘 𝑇 , a simple estimate from persistence length predicts a size of stable nanobubble sizes that are around 100 nm (diameter). If 𝜅 ≪ 1𝑘 𝑇 the bulk nanobubbles would become unstable and we expect the disappearance of the nanobubbles within a short time.