The rather specific nature of the decision nodes in the right branch resonates well with the general understanding that carbohydrates with an axial C-2 substituent strongly favor the 1,2-trans product in glycosylations and specialized methodologies with limited substrate scopes are necessary to obtain the 1,2-cis product. In summary, according to the decision tree algorithm, when the C-2 substituent has a -1 configuration, β-selectivity is expected unless the C-2 substituent of the glycosyl donor is an azido or benzyl group, with the azido-group being particular α-directing. Whereas if the glycosyl donor's C-2 configuration is 1 or 0 (corresponding to a 2-deoxy glycoside), the glycosylations are α-selective unless the glycosyl donor is a "5-deoxy sugar" or has a benzylidene.