models for the quinone dataset (average absolute errors (AAE): 29.5 °C), but the thermodynamic features in the thermodynamic model resulted in lower prediction errors for the hydroquinone dataset (AAE: 35.4 °C). These results emphasize the importance of including intermolecular interaction descriptors, especially for classes of molecules in which these interactions are expected to be strong (e.g. hydrogen bonding in hydroquinones). As a byproduct of this study, we also consolidate (from previously published data) four new datasets with quinone and hydroquinone melting points and other key features.