Parkinson's disease is associated with a wide range of non-motor symptoms that can significantly impact quality of life. These include cognitive impairment, psychiatric symptoms (such as depression, anxiety, and psychosis), autonomic dysfunction (e.g., constipation, urinary problems, orthostatic hypotension), sleep disturbances, sensory symptoms (e.g., hyposmia, visual disturbances), and others. Dysfunction of mitochondria, the cellular organelles responsible for energy production, has been implicated in the pathophysiology of PD. Mitochondrial impairment can lead to energy deficits, increased oxidative stress, and activation of cell death pathways, contributing to neuronal degeneration. Mutations in genes associated with mitochondrial function, such as PINK1 and Parkin, have been linked to familial forms of Parkinson's disease.