Next, we investigated the selectivity of the Strecker synthesis of ↵-amino acids. For this system, we employed regression models due to the continuous nature of the target values (enantioselectivity G ‡ ). Our workflow involves the examination of fingerprints (Notebook 5), Mordred descriptors (Notebook 6), and QM descriptors (Notebook 7). We briefly compare the results from each approach and provide a more detailed discussion of the results from Notebook 7.