To the basic aqueous phase is added sodium chloride (480 kg, 1.6 X) and the resulting phase is extracted with 2-MeTHF (2560 kg, 8.54 X then 1280 kg, 4.27 X). The combined organic extracts are then concentrated under reduced pressure. Azeotropic distillation is then performed with additional 2-MeTHF (1030 kg, 3.42 X) until the water content is not more than 0.5% w/w as measured by Karl Fischer analysis. After charcoal treatment, the resulting solution is heated to approximately 45-55 °C and treated with a solution of L-tartaric acid (84.0 kg, 0.28 X, 1.00 equiv.) in IPA (942 kg, 3.14 X). The reaction mass is cooled to 20-30°C causing intermediate MR84910 Tartrate salt to crystallize. The solids are then isolated by filtration, washed with successive portions of 2-MeTHF (63 kg, 0.21 X) and dried. 326 kg of white solid was obtained with 70.75 wt% assay as the free base and 95.9% a/a purity (80% yield).