For HTI switching in vacuum, only the DBI torsion angle 𝜃-C=Ccould be identified as a significant descriptor for triggering relaxation to S0-Z versus S0-E from the S1-state. In fig. , this is indicated by a well-defined sigmoid shape of the fitted function p(x) for predicting the committor probability p(S1→S0-E,x). For comparison, we also show the fitting of eq. 3 in case of using the SBR torsion angle 𝜃=C-Cas a putative descriptor. In this case, we indeed find ω=0 and a rather indifferent approximation of p(S1→S0-E,x) = constant. A more subtle picture is however observed for HTI photoswitching in solution. While the 𝜃-C=Cangle is still of central importance for Z-E isomerization, we identified two solvent coordinates as additional descriptors for predicting our committor analyses.