ROMANCE v2 has been introduced to perform these corrections, and also give more control to the user over the transformation parameters including the possibility of using multiple markers, field ramps, and selecting different ionization and detection regimes. We have validated the theoretical framework by studying peak position and area precision under the several transformation formulas shown in the article, showing the need to use the right area transformation to have reliable quantitative data. Finally, we have seen that with the current version of ROMANCE the worfklow is ready for multivariate analysis of real metabolomics data, achieving a significant milestone in the path to make CE-MS part of the metabolomics toolkit.