Rompicharla et al. also showed that PEG-PLGA micelles are capable to solubilize around 1.8 g/L of VOR , similar, albeit lower than achieved here. Further increase in VOR feed, did not improve the solubility, in fact it fell below 2 g/L. For A-pBuOx-A, the solubility of VOR remained around 2g/L while a slight decrease was observed in the case of A-pPentOx-A (≈ 1.1 g/L) and A-pBuOzi-A (≈ 1.0 g/L) at higher VOR feed. For A-pPrOzi-A, a dramatic decrease was observed from 2 to 6 g/L VOR feed (solubility dropped from 1.7 to 0.4 g/L). Further increase in VOR feed led to complete precipitation of formulation and no further quantification was possible.