The surface tension of the liquid/vapor interface originates from the energetic preference for molecules to be located in the bulk liquid compared to at the surface, thus it is a property that characterizes the cohesive forces in the liquid, similar to the heat of vaporization. Furthermore, because the surface tension calculation does not involve taking any energetic differences with molecules fully in the gas phase, we hypothesize that it can substitute for the heat of vaporization in the force field parameterization without requiring corrections for polarization or nuclear quantum effects. Indeed, the nuclear quantum effects are smaller for the surface tension compared to heat of vaporization, as the heat of vaporization increases by 2.1% from H 2 O (40.657 kJ mol -1 ) to D 2 O (41.521 kJ mol -1 ), while the surface tension only changes by 0.15 % between light and heavy water (from 71.98 mJ m -2 to 71.87 mJ m -2 ). This is further supported by established protocols for calculating surface tension in MD simulations, in which all post-hoc corrections are intended to account only for long-range dispersion interactions.