In this study, we show that I. sakaiensis can ferment PET into acetate and ethanol under anaerobic conditions yielding ATP by substrate-level phosphorylation (Figure ). In addition to PET, other substrates such as maltose, EG, and ethanol can also be fermented into value-added chemicals by I. sakaiensis. Co-culturing of I. sakaiensis with the bacterium Geobacter sulfurreducens (G. sulfurreducens) attached on a porous inverse opal-indium tin oxide (IO-ITO) electrode in a microbial fuel cell produced electricity from PET or EG, where I. sakaiensis provided acetate as a substrate for G. sulfurreducens from the fermentation of PET or EG. Instead of aerobically producing CO2 and H2O as the end products, we demonstrate in this work the anaerobic ability of I. sakaiensis to convert PET into high-value chemicals and, upon coculturing with G. sulfurreducens, the generation of electricity. Both pathways provide an economic opportunity to mitigate plastic pollution while co-producing chemicals and energy.