As reported previously, changing the position of the electron donor in the dye can affect the AIE/ACQ behavior. In the present study such a pair of regioisomers is repre- The introduction of strong electron donor is expected to intensify the described behavior (compare Ref. ). Furthermore, introduction of the second substituent of the opposite, electron-accepting, character in the 3 and 7 pair of regioisomers, indicates the opposite molecular topology is the driving force of the opposite mechanisms associated to emission change. The AIE/ACQ effects for such a pair bearing both D and A substituents is significantly enhanced with respect to only-D substituted dyes.