Nanotechnology is used in the development of new drugs and reformation of the extent ones; it also enhances their potency, low risk of toxicity, reduces side effects, concede the use of reactive substances such as curcumin . It also increases the permeability of Curcumin towards the metabolic process . It also develops controlled drug release and drug targeting by producing circulation time by protecting the molecule from incomplete degradation. Curcumin is a drug which is nearly insoluble in aqueous solution and has low bioavailability; so, the nanoparticles are used in such cases as the nanoparticles increase the bioavailability and target the desired tissue or microbes . According to Whitney Noyes Equation, reduction in drug particle to nanoscale results in higher dissolution rate and higher surface area which makes its efficient for drug release and drug loading. The Whitney Noyes equation is given as: