A flexible sequence-defined polymer chain is modeled as freely-jointed tangential hard spheres, composed of p N blocks, where the th m block of a polymer chain has In our model, two adjacent monomers in a polymer chain are tightly connected by the bonding potential d  + = . Apparently, Eq. ( ) is essentially the bonding potential of an ideal flexible chain (i.e., random-walk or freely-jointed chain). The external interaction between hard wall and particle i is described via hard-wall potential, ( )