Global and channel-specific rate constants can be computed solving the multi-well onedimensional master equation using the chemically significant eigenvalues (CSEs) method within the Rice-Ramsperger-Kassel-Marcus (RRKM) approximation, as implemented in the MESS code. The collisional energy transfer probability is described using the exponential down model 63 with a temperature dependent ∆E down of 260 × (T /298) 0.875 cm -1 in an argon bath gas. For channels ruled by a distinct saddle point, rate coefficients are determined by conventional transition state theory (TST) including tunneling as well as non classical reflection effects by the Eckart model. Instead, rate constants for barrierless elementary reactions are computed by the phase space theory (PST). The isotropic attractive potential V eff entering the PST is described by a C R 6 power law, whose C coefficient is obtained by fitting rDSD energies computed at various long-range distances between the fragments.