The bulk, shear, and young moduli can be used together to detect anomalies MOFs. Indeed, the average modulus, estimated using the Hill method may not truly reflect the factual strength of the framework and its resistance to collapse. Therefore, in present work, the lower bound of the moduli (estimated using Reuss method) were used for anomalies detection. Here, the young modulus was plotted against the bulk modulus (Figure ). It is important to note that for very few structures, the estimated properties with Reuss method were greater than that obtained from the Voigt method, which is counter intuitive.