In summary, electrochemical investigation on 8AQ revealed that the drugs containing 8AQ as the core of their structure should not undergo a reduction reaction in the human body due to the very low potential of this process. However, such medicinal substances may undergo oxidation reactions in the human body due to activity of cytochromes P450 or peroxidases, as the oxidation potential of 8AQ is ~ 0.6 V (vs. Ag/AgCl). Key words voltammetric methods, 8-aminoqinoline, computational studies.