Our framework can be fine-tuned to describe systems requiring more chemical information. The extension of the model to C 2+ products is feasible by adding additional reaction pathways into the DFT-microkinetic model. On the transport side, concentrated potassium acetate solutions can break the steric limit concentration due to the chelating properties of the counter anions, likely affecting the transport of CO 2 and K + . The model could also accommodate precipitation limits or electrolytes containing high concentrations of organic cations that will require to take into account a H 2 O modulation and different mechanisms for transport of reactants at OHP, in addition to the cations. Finally, our framework could be expanded to complex pore-scale resolved geometries or effective domains describing complex devices configurations such as Gas Diffusion Electrodes (GDEs) and also to complex reaction networks.