Overall, this study demonstrates the excellent capacity of PSPMA brushes to capture heparinbinding growth factors such as BMP2. The simplicity with which PSPMA can be generated via ARGET, even in ambient atmospheric conditions, without particular precaution to preclude oxygen contamination, will enable the coating of a broad range of materials and potentially implants with complex 3D shapes. Considering the importance of promoting matrix deposition in order to ensure soft tissue bonding to the surface of hard materials and implants, heparinbiomimetic PSPMA brushes may find application as coatings promoting tissue integration.