Interestingly, traditional flexible Vina docking with Vina scoring functions and the same inputs, docking box size, etc., did not identify a single active drug from the list of 14 above. Using the Vinardo scoring function, the situation improved, identifying two known active drugs from the list of 14: NICLOSAMIDE, which ranked 24th for inhibiting the 6LU7 target, with an estimated binding energy of -5.981 kcal/mol, and ELTROMBOPAG, which inhibited all three targets.