Given that production yields for full AAVs are generally low, the high sensitivity of the ZipChip can provide a platform for rapid serotype identity confirmation and VP proteoform identification. Here, a decreasing number of viral particles (Vps) were injected to test the LoD for the ZipChip CE-MS for sample dilution details). This roughly corresponds to a mass range of ≈220 pg -≈26.4 pg of sample being used for LoD evaluation, assuming 1.00 × 10 13 Vps equals 100 µg. The electropherograms of the analysed samples show two distinct sets of peaks (Figure ).