A 10 mL round-bottom flask was charged with a stir bar, N-H aziridine silanol substrate (1 equiv.), and CH2Cl2 (final reaction concentration of 0.1 M). The reaction flask was cooled to 0 °C using an ice-water bath. Methanesulfonyl chloride (MsCl) (1.2 equiv.) was added dropwise. Subsequently, Et3N (1.5 equiv.) was added dropwise. The ice-water bath was removed, and the reaction mixture was allowed to warm to room temperature over a period of 1 hour. Following this time, the reaction mixture was diluted with CH2Cl2, transferred to a separatory funnel, and washed with one portion of 0.2 M aqueous HCl solution.