2.2.1. Purification, NMR spectroscopy, and mass spectrometry Flash column chromatography was carried out using a CombiFlash NextGen automated column from Teledyne ISCO, with solid loading of samples using silica gel (Silia-P from Silicycle, 60 Å, 40-63 µm). Analytical thin-layer chromatography (TLC) was performed with silica plates with aluminum backings (250 µm with F-254 indicator). TLC visualization was accomplished by 254/365 nm UV lamp. NMR spectra were recorded on a Bruker Advance spectrometer (400 or 500 MHz for 1 H, C and 19 F). The following abbreviations have been used for multiplicity assignments: "s" for singlet, "d" for doublet, t" for triplet, "m" for multiplet, and. 1 H spectra were referenced to residual solvent peaks with respect to TMS (δ = 0 ppm). Electron-spray ionization (ESI) high-resolution mass spectrometry (HRMS) spectra were obtained at the University of Edinburgh Mass Spectrometry Facility. GCMS spectra were recorded using a Shimadzu QP2010SE GC-MS equipped with a Shimadzu SH-Rtx-1 column (30 m × 0.25 mm).