Plasmonic nanoparticles can absorb and convert light into heat due to a photothermal process known as plasmonic heating. In particular, gold nanoparticles (AuNPs) are commonly used as plasmonic nano heaters in a wide range of applications including hyperthermia-based tumor ablation, selective protein inactivation, nanobubble theranostics, nanothermometry, photothermal imaging, and photoacoustic imaging. Interfacial heat transfer is particularly relevant for nanoscale heat transfer because individual nanostructures exhibit a high surface-to-volume ratio and their ensembles have a high density of interfaces. As such, heat transfer through the interface between a AuNP and its surrounding medium is an important element of the plasmonic heat dissipation process. A thorough understanding of AuNP thermal interface conductance can be critical for precise control of plasmonic heat generation and its applications. Interfacial heat transfer can be characterized by the thermal interface conductance (G), which quantifies the rate at which heat flows through an interface between two adjacent media at different temperatures. Experimental studies indicate that the thermal interface conductance of nanoparticles is affected by the chemical composition of the nanoparticle, its ligand coating, and the surrounding medium. Molecular dynamics simulation studies of solid nanospheres immersed in mono-atomic fluids and nanodroplets of n-decane in water suggest that interface curvature (inversely proportional to particle size) and temperature can also affect nanoparticle thermal interface conductance. Recent molecular dynamics studies also report that AuNPs immersed in organic solvent exhibit curvature dependent changes in thermal interface conductance. Although previous experiments indicate that characteristic times for AuNP cooling in water scale with particle surface area, it remains unclear if interface curvature or temperature affect the thermal conductance at nanoscale gold-water interfaces. These factors are of practical importance in biomedical applications that utilize plasmonic heating of AuNPs because the AuNPs are embedded in primarily aqueous media and may experience significant temperature variations.