While the screening sequence is ongoing, these plots are redrawn after each single measurement. This strategy allows for easy oversight by the operator, is effective in managing and analyzing the large volume of data that is being generated and allows for an early analysis of potential trends in real-time as the flow parameters are changed. For example, for Figure (a) one can observe a sudden drop in particle size once the highest mixing ratio is reached. The method shows that the drop is statistically significant, and that the particle size is essentially halved when going from 60/40 to a 50/50 ratio. Such sudden changes are often observed at high mixing ratios. The high organic solvent content allows for a higher chain mobility in the nanoaggregates, and hence allows the particle to get closer to its thermodynamic equilibrium under the given solvent conditions. A such sudden and sharp change, however, is likely indicative of morphological changes. DLS analysis always assumes a spherical morphology of particles. Thus, if particles are elongated to form rod-like shapes, or even show a shift to vesicle morphologies, DLS is unable to accurately reflect these changes.