Interestingly, the latter kind of organic spacers links, through the amino group, isolated iodide anions, whose presence is necessary to balance the excess of positive charges. Also, the other (R-)AMOL linkers interact with them through the terminal carbon atoms and the adjacent ones, featuring C-I distances shorter than 3 Å. Therefore, a clear hydrogen bonding network involving the hydroxyl group is found, together with the common N-H•••I interaction of metal halide perovskites. There are few examples of perovskites containing bifunctional organic spacers with -NH2 and -OH, namely [(HOCnH2nNH3)2PbI4] with n = 2 11,12 and 3 . Noteworthy, in these examples, the linkers are linear with the two functionalities at the opposite sides, generating 2D layered structures. It is also worth mentioning a single example of another low-dimensional perovskite composition including isolated iodide ions in the structure (as the present samples), namely the 1D system reported by Lemmerer and Billing, where the organic ligand was as well a bifunctional molecule, namely 2,2'-dithiodiethnammonium, including sulfur and amino groups. The present ligand is a novel molecular entity not yet used in any perovskite, and clearly in any chiral perovskite, and resulted in a novel structural arrangement and polar interaction network. In addition, it is interesting to observe that this is the first chiral ligand where the chiral carbon does not bear an amine group but a hydroxyl group. The level of octahedral distortion has been quantified in terms of the octahedral quadratic elongation (λoct), as defined by Robison et al., as well as by calculating the distortion index, D. The bond lengths vary between 3.08 and 3.42 Å leading to slightly distorted octahedra. The distortion parameter is 0.036 which places the present material as an intermediate distorted compound even though such comparison is based on available data on 2D perovskites, being the structure reported in this work not common. The stability of [(R-/S-)-AMOL]2PbI3•I samples has been assessed by differential scanning calorimetry (DSC) and thermogravimetry (TGA). The DSC traces, Figure , in the temperature range -80-110°C do not reveal the presence of any peak, indicating the absence of structural transitions in this interval. The TGA measurements, Figure The absorption spectra, calculated from the reflectivity of powdered samples, show an absorption edge for the two chiral perovskites around 420 nm. The band gap extrapolated from the Tauc plots (see Figure ) for a direct transition are 2.87 eV. Figure shows the CD spectra for the two samples which have opposite features confirming their chirality. Four very intense CD peaks with opposite sign are clearly visible in the range 315-403 nm, with this last one well corresponding to the absorption edge. While we recognize that the mdeg value is not an absolute scale since it has a dependance with the sample amount, the present films, of thickness around 400 nm, present one of the highest values of CD response reported to date, indicating their potential use in efficient circular polarized light photodetection. The respective chiral ligands do not show any relevant CD in the UV-Vis region, as anticipated based on their molecular structure, therefore all the chiroptically active transitions derives from a chirality transfer from the chiral bifunctional ligand to the inorganic network. It is interesting to note that an effective chirality transfer occurs also when an interaction network is established by means of -OH groups, while all the previous examples of chirality transfer to the inorganic framework were based on the hydrogen bonding trough the protonated amine group. The peculiar derivative-like features of the CD signal around the band edge (at 402 and 388 nm) suggest a lifting of the spin degeneracy within the electronic states at the edge induced by the chiral molecules defined as the Cotton effect. The chiral anisotropy factor, gCD, has been calculated from the CD measurements and resulted to be around 3 × 10 -3 . Since no other chiral perovskites possessing the structural motif of the present samples or including a similar ligand are present in the current literature, a direct comparison of the chiroptical properties with available data is not straightforward. However, these values are in line or slightly higher with respect to data reported for some 2D chiral perovskites. In conclusion, in the present paper we reported the design and synthesis of the first pair of enantiopure bifunctional chiral ligands containing both a hydroxyl and an amino group. The two chiral molecules have been used to synthesize lead iodide compounds leading to the discovery of the 1D low-dimensional material of formula [(R-/S-)-AMOL]2PbI3•I featuring a quite peculiar and uncommon structural topology. The chiroptical properties confirm an effective chirality transfer from the ligands to the inorganic framework providing a very intense CD response. The reported family of novel chiral ligands pave the way for the required extension of the field of chiral perovskites in terms of materials and properties engineering.