Lipid17 has the largest APL across the entire CHOL contration range. MacRog also has a large APL for pure POPC, but the partial area of CHOL is negative until 30 mol-% concentration, indicating a particularly strong condensation eect. The proles for Slipids and CHARMM36 are very similar, with a small or zero partial area of CHOL until a concentration of 20 mol-%.