Bone remodeling is responsible for preserving bone's mechanical strength by replacing damaged tissue with healthy one as well as calcium and phosphate homeostasis. Trabecular bone is more active in remodeling which leads to lower mineralization (newly formed bone has lower mineralization than the older one). Trabecular bone demonstrates 26% volume per year turnover rate, which is significant in comparison to the 3% for cortical bone . This indicates that trabecular bone plays a particularly significant role in mineral metabolism, as newly formed bone due to its lower mineral content is able to better exchange ions with intracellular fluid. Cortical and trabecular bone follow the same bone remodeling mechanism, with bone remodeling units in trabecular bone equivalent to cortical bone remodeling units divided into half longitudinally. It is important to note that trabecular bone balance is mildly negative in adult life, which explains trabecular thinning with aging . Blood marrow is present in the medullary cavity of the long bone and all trabecular bone which serves as a scaffold. Trabecular bone equals around 20% of bone tissue mass, has a porosity of around 80% (due to which, the surface area of trabecular tissue is 10 times larger than that of cortical bone) and has a density equal to 1820 kg/m 3 . Above mentioned properties allow the trabecular tissue for energy absorption, load transfer, and metabolic activities such as bone cell metabolism and bone marrow erythropoiesis.