Electrochemical research focuses on optimizing LIG synthesis, developing LIG into reliable sensors by understanding phenomena, like charge transfer and mass transport, and exploring functionalization strategies. Batch-to-batch consistency of LIG electrodes remains a challenge compared to commercial screen-printed electrodes. Crucially, the proposed LIG electrochemical sensors often lack in vivo or on-site real-world testing data, limiting understanding of their true feasibility, long-term stability/durability and susceptibility to interferents/fouling from complex sample matrices, like biological fluids.