Finally, the observed scaling behavior of the computed statistical uncertainties has immediate consequences for the preferred simulation setup: assuming that the computational cost scales roughly with the number of particles in a simulation, our data suggest, that it is always preferable to increase the simulation length instead of the system size. In fact, it is advised to use the smallest simulation size possible, in this case: a size of 768 molecules or ion pairs. From our study we find no evidence pointing that data obtained for this system size are deviating systematically from simulations of larger systems.