Following synthesis, the crude reaction mixture was manually filtered and transferred to the HPLC-MS device for characterization. Purification (HPLC-MS) and spectroscopic characterization (custom-built automated optical characterization platform) were controlled by ChemOS 2.0 through SiLA2 commands. The desired product was successfully detected by HPLC-MS, and the purified product underwent downstream optical property analysis. All data produced during this test can be found in Note S14.