System set-up: The 3D models of Lauric Acid (LAU), Dodecyl Phosphocholine (DPC), Dodecyl Dimethyl Ammonio Propane Sulfonate (DAS), Dodecyl Dimethyl Amine-oxide (DDA) and Sodium Dodecyl Sulfate (SDS) were built using the Micelle/Membrane Builder facility of CHARMM-GUI . 54 lipid molecules were packed in random positions and orientations in a simulation box of 7.4×7.4×7.4 nm 3 using the gmx insert-molecules tool of Gromacs 2020.2 () for each system. The molecules were in high concentrations (~220mM), well above their CMC. The systems were solvated with TIP3P water molecules. Each box was replicated by periodic boundary conditions. Sodium or chloride ions were added in random positions to achieve a neutral net charge of the systems. The minimization procedure and set-up of molecular dynamics (MD) simulations were performed with GROMACS 2020.2 program package using the CHARMM-36 all-atom additive force field containing lipid parameters . The real space summation of electrostatic interactions was truncated at 1.2 nm, and the Particle Mesh Ewald (PME) method was used to calculate the electrostatic interactions beyond 1.2 nm with a grid spacing of 0.12 nm and an interpolation order of 4. Van der Waals interactions were calculated using a cut-off of 1.2 nm. The solvated systems were energy minimized to eliminate unfavorable positions. Harmonic positional restraints were applied on lipid head group atoms -carboxyl oxygen for LAU, phosphate phosphorus for DPC, ammonium nitrogen for DAS, ammonium nitrogen for DDA and sulfate sulfur for SDS -and tail group atoms -carbons at positions 4, 8 and 12 -to achieve smooth minimization. 5,000 steps of steepest descent algorithm was used, adopting harmonic force constants of 1,000 kJmol -1 nm -2 for the abovementioned lipid atoms. The minimized systems were equilibrated over 2 successive runs: 125ps (NVT, 1fs time-step) and 200ps (NPT, 2fs time-step). To allow water molecules and ions to adjust around the lipids, harmonic restraints with a force constant of 1,000 kJmol -1 nm -2 were applied on the same lipid atoms as in the case of the minimization step.