Importantly, the polarization is no longer governed by the detection magnetic-field strength, but rather the hyperpolarization method and details of the hyperpolarization procedure. Parahydrogen-induced polarization (PHIP) and spin-exchange optical pumping (SEOP) have been used to hyperpolarize samples for zero-and moderate-field NMR experiments, but PHIP relies on specific chemical reactions with hydrogen gas, and SEOP is limited to polarizing noble gas atoms.