Lastly, we have successfully deployed the aforementioned middleware unit in our experimental laboratory. Figure illustrates our current setup, which includes: (a) The Machine (Note S6): a robotic pump system capable of parallelized synthesis in solution, (b) Chemspeed platform, an automated robotic framework for parallelized synthesis and characterization workflows (Figure ), (c) a High-Performance Liquid Chromatography/Mass Spectrometetry (HPLC-MS) device (Note S4) for compound separation and identification, and (d) the custom-built automated optical characterization: a flow setup for automated spectroscopy (Note S5). The available commands for each of the experimental units can be found in Tables S1-S5. To test the SiLA2 server before deployment, we used "simulation" versions of the workflow managers (Note S8), ensuring minimal interruptions of operations while the server is in development. The operations of each instrument are controlled by an independent computer connected to the local network. The instruments of the laboratory can be used in-sequence or individually.