Compatibility with RAFT polymerization. We showed that the POT could be a valuable alternative to DOT to obtain degradable organic polymers. We thus investigated its compatibility with RDRP (reversible-deactivation radical polymerization) technique, and we chose to test RAFT polymerization since this process is compatible with the temperature we already tested. To ensure the compatibility, we aimed at preparing block copolymers with styrene and IBA. In the case of these monomers, the best order to prepare diblock copolymer is to synthesize first a PS macroinitiator to reinitiate the polymerization of IBA. As POT is compatible with both monomers, we added either POT in the first block or in the second block or both (Figure ). Two PS macroinitiators were prepared having or not 5 mol% of POT. We used the 2-(dodecylthiocarbonothioylthio) propionic acid (DoPAT) as RAFT agent and performed the polymerization in bulk at 80°C for 20 hours. Similar macroinitiators were obtained (see ESI for details) with Mn close to 10,000 g.mol -1 and 70-80% conversion. Only a small broadening of the molar mass distribution could be noticed. From these two macroinitiators, the polymerization of IBA without or with 1 mol% of POT was performed. We chose this amount of POT since it will allow an insertion of thioesters units close to 5 mol% if the conversion is kept below 60% (Figure ). All the details of the polymerization are given in the ESI. The molar mass distributions before and after degradation via TBD are shown in Figure . In all cases, there is a rather good re-initiation efficiency of the polymerization of IBA with block copolymers having Mn in the range of 20,000 g.mol -1 . A tailing of the molar mass distribution is nevertheless observed when the P(S-co-POT) was used. The degradation using TBD at room temperature for 1 hour was then performed on all the block copolymers and showed the expected degradation profiles. When a pure PS block was used and POT was inserted only in the second block, the degradation of the block copolymer led to a polymer with a Mn close to the fist PS block that is attached to a small amount of IBA. When POT is inserted into the first block and not in the second block, the degradation released only the second block PIBA whose Mn value is close to the one obtained by subtracting the Mn of the first block to the one of the copolymer. A dual detection SEC confirmed the absence of a UV signal at 254 nm and thus PS was discarded (Figure in ESI). When POT was inserted into the two blocks, the degradation products have very small Mn confirming the degradation of both blocks and the efficiency of this technique.