Chemical species transport through diffusion is a fundamental process occurring in the GI tract, driven by concentration gradients. It is essential for nutrient absorption, drug delivery, and waste removal at cellular and systemic levels . The diffusion of ions, nutrients, and medication across the epithelial lining of the GI tract and their subsequent reactions play vital roles in maintaining physiological homeostasis. For instance, diffusion of hydrogen ions and their neutralization by bicarbonate ions are critical in preventing mucosal damage and ulcer formation . Peristalsis, a well-known convective process in the GI tract, ensures the propulsion of ingested material through the digestive system . This process is vital for moving chyme through the intestines and bolus through the esophagus. This coordinated muscle contraction is essential for not only moving food but also for mixing it with digestive secretions, thereby enhancing enzymatic activity and nutrient absorption. Peristalsis works concomitantly with molecular diffusion to distribute nutrients and remove waste products efficiently. These mechanisms aid in maintaining the local microenvironment essential for gastrointestinal function .