Autocatalysis with asymmetric amplification provides an elegant solution to the question of the emergence of homochirality characterized by two features: i) a symmetry breaking transition that is highly sensitive to small asymmetric influences; and ii) a reaction that exhibits a higher order burst of autocatalytic activity. The first feature allows for high selectivity; the second is required to maintain this selectivity above stochastic noise and to propagate the selective pathway at the expense of that of its enantiomer. While the Soai reaction remains the sole documented example of the theoretical Frank model for spontaneous asymmetric synthesis, the search to discover an autocatalytic network that exhibits these features and at the same time exemplifies prebiotically plausible chemistry is ongoing. Homochirality might have involved not a single reaction or event but rather a series of persistent chemical and physical processes acting synergistically as a key part of the emergence of life on earth.