Many of these simulation parameters are similar to those from Part 1. So unless otherwise stated, all AA simulations in OPLS were run for 2 ns with a 2 fs timestep, using the vrescale thermostat and Parrinello-Rahman barostat with a τ T of 0.1 ps and a τ P of 8.0 ps and a compressibility of 4e -5 bar -1 . Likewise, unless otherwise stated, all CG simulations in MARTINI were run for 5 ns with a 2 fs timestep, using the v-resale thermostat and Parinello-Rahman barostat with a τ T of 0.1 ps and a τ P of 12.0 ps and a compressibility of 3e -4 bar -1 . For both AA and CG simulations, electrostatic interactions were calculated using Particle Mesh Ewald (PME) with a real-space cutoff of 1.2 nm and long-range Van der Waals interactions had a cutoff of 1.1 nm. For the CG simulations, the PME calculations were performed with a 0.25 Fourier spacing. All simulations were run using the GROMACS software on the Discovery cluster.