In a multitude of the aforementioned applications, e.g. the creation of the GEOM 17 dataset, the inclusion of solvation effects plays a crucial role to be able to reproduce experimental conditions. In the xTB methods, this is achieved via the inclusion of tailored implicit solvation models, namely a generalized Born/Surface Area (GBSA) model, and the analytical linearized Poisson Boltzmann (ALPB) 28 model. Both of these models were specifically parametrized for the respective methods and can be invoked by simple command line keywords.