Although the fluid itself may be achiral, shear vorticity of the fluid introduces a dynamic chiral environment that can induce separation. Shear vorticity is the rotation of an object induced by a velocity gradient in a fluid undergoing shear flow. The potential separation of enantiomers by achiral fluid flow was reported by Howard et al. Inside a rotating drum, Howard and coworkers suspended dextro-tartaric acid crystals in Isopar H (isoparaffinic hydrocarbons), and observed pure macroscopic enantiomers moving in specific directions depending on the Isopar H flow. Howard et al.'s idea has been extended to separating biological and manufactured chiral objects (not molecules) at the mili, ,13 micro and nano scale. These observations contradict a simple theoretical model of Tencer and Bielski, which suggests an impractical amount of time required to resolve micro-scale or smaller chiral objects. With these experimental and theoretical discrepancies, Hermans et al. have recently emphasized the necessity of theoretical studies at the small scales, particularly on real molecules with all intermolecular interactions treated in a realistic manner.