The intensity of scattered laser light over time is then recorded at a certain measurement angle (e.g., 90°, 175° or 15°). Batch mode DLS does not require tedious sample preparation and allows to acquire information on particle size (distributions) in a fast and reliable manner. However, batch DLS struggles to accurately characterize broadly distributed particle dispersions (i.e., with high dispersity in particle size), which can be resolved to some degree by using a multiangle detector setup. Moreover, irregularly non-spherically shaped particles invalidate assumptions used for calculating the particle size, thus the obtained values must always be interpreted with caution or complemented with other techniques. Microscopy such as AFM, SEM or TEM are used to determine morphology and shape of the analyzed particles, since DLS cannot not provide such information. Moreover, the reliability of quantitative analyses (e.g., of particle size) often suffers from the limited sampling size and user bias. As a result, a combination of the above mentioned analytical techniques is often necessary to obtain sufficient and verified information on the size, shape and morphology of LNPs. In this regard, a method providing both authentic particle size distributions and information about the shape of LNPs would be of great interest.