In this review, we will provide an overview of approaches that have achieved spatial and temporal control in catalytic systems that have enabled integrated catalysis or that we envision can be implemented for integrated catalysis. Seminal studies illustrating spatiotemporal control of catalysts will be presented to showcase their impact on some of the most challenging problems in catalysis. We will also discuss developing a toolbox of spatial and temporal methods for integrated catalysis, followed by limitations and suggested optimizations. Lastly, we will provide an outlook of directions in which integrated catalysis is likely to make progress.