An indication of the complexity of this system can be gained from the fact that an attempt to carry out a ring closure reaction from acetamide, in the expectation that 3methyl oxaziridine would be formed, proved illusory, Fig. . Yet another dipolar compound is formed whose formation enthalpy of 312.4 kJ mol -1 (296.1 at 298.15 K) and dipole moment of 3.88 D makes it akin to species (c) of Fig. species is detectable or not then it is unlikely that any of the chiral cyclic molecules featured here will qualify. More generally are any of the acyclics likely candidates? If only those species which lie within an arbitrary 100 kJ mol -1 are worthy of consideration then 1-amino ethenol, amino acetaldehyde, ethanimidic acid, methyl formimidate and N-methyl methanimidic acid qualify. However all of these have dipole moments towards the lower end of the scale. Another consideration that can impact on the detectability of these compounds are the number of low-lying conformers which effectively reduces the population and hence the intensity of a particular rotational transition.