In summary, we present the synthesis of a novel amphiphilic double stimuli responsive (PAAla-b-PMMA) diblock copolymer via Zinc mediated RDRP. The copolymer is made of which has the Polyalanine hydrophilic moiety. This transformation was achieved through a mechanistic transformation from living radical polymerization. It is possible to combine the functions of two distinct terms (synthetic polymer and biomolecule) with this new class of innovative biohybrids.