To generate their co-evolutionary children, the DW-BEL Docking-Score criteria was selected with its highest weight (weight = 4). To increase specificity, Molecular <=400 g/mol (4), hydrophobicity clogP <=3 (1) and several Toxicity Risk values (4), were also selected. Other variables were Create compounds like: Approved drugs, and Total round count = 1. The preliminary conclusions of the prediction results with several Toxicity Risk values, were the following (Figure i) Number of raw children. There were 13033-15827 raw children randomly generated for Toxicity Risk values between 0 to 2. Lower 5695 raw children were predicted with 4 as Toxicity Risk value.