We propose an analytical framework for the detection, localization, and quantification of single-source methane emissions on relatively simple oil and gas production sites. When tested on single-source, non-blinded controlled release data, all releases are detected and 82% are localized correctly. For emissions > 1 kg/hr, quantification estimates have an average percent difference of 4.3% from the true rate and 90% of estimates are within a percent difference of .8%] or a factor difference of [-2.0, 1.8] from the true rate. Note that further blinded testing is needed to more rigorously assess framework performance.