Next, we performed a state change from the coated to the armored DNA condensates by connecting the 3D DNA origami with a 'connector' input (Figures and; Table ). We used the one-sided binding design with 20 condensate-binding tags. The 3D DNA origami had 4 origami-connecting tags for each edge. When the connectors were input to the coated DNA condensate solution, the connectors bridged the origamiconnecting tags and connected the 3D DNA origami (Figure ; Table ). Figure shows a CLSM image of an armored DNA condensate and its fluorescence intensity profile. There was no significant difference in I surface /I internal between before and after the armoring (Figure ), suggesting that the armoring did not change the distribution of DNA origami on a DNA condensate. In the case of the 2D DNA origami, armored DNA condensates were not obtained because of the low efficiency of coating DNA condensates (Figure , Table , Supplementary Note S1). profile of an armored DNA condensate using the one-sided binding design of 3D DNA origami with 20 condensate-binding tags. DNA origami was labeled with FAM. After armoring, the final concentrations of total DNA condensate motifs, DNA origami, binder, and connector were 0.47 µM, 1.89 nM, 0.31 µM, and 1.05 µM in the FoB5 buffer, respectively. Details in Experimental Section. Scale bars: 3 µm. c) Violin plots of I surface /I internal before and after the armoring. n=20.