Although the aryl chloride gave a lower yield on average, it can still be interesting to investigate what conditions are successful for this substrate, for example, the aryl chloride substrate may be more favorable for cost or availability reasons. Therefore, we looked into which suitable reaction conditions are able to transform the aryl chloride substrate into the desired product. Using the parallel coordinate visualization (see Figure ), it was observed that for a moderately high yield, Pd0-t-Bu-C-Phos was the best-performing ligand and performed well with all bases. This is in contrast to the aryl iodide substrate, which gave high yields with three possible ligands but not with P 2 Et as the base.