We inquire whether the asymmetric decarboxylative C(sp 3 )-C(sp 3 ) cross-coupling reactions could employ moderate organometallic reagents to install versatile chiral alkylboron derivatives，which possess a diverse reactivity profile crucial for drug discovery and material sciences . Considerable effort has been devoted to exploring synthetic methodologies for the preparation of these scaffolds . Among them, asymmetric transformations of abundant and easily accessible feedstock chemicals offer an appealing synthetic platform toward chiral alkylboron derivatives but remain elusive. Pioneering works by Li , Baran , Aggarwal and substantial progress on decarboxylative borylation of aliphatic acids underscore the reliability of decarboxylative reactions in synthesizing alkylboron derivatives. Nevertheless, methods for constructing chiral alkylboron derivatives via asymmetric decarboxylative cross-coupling reactions of unactivated primary aliphatic acids have yet to be reported.