To illustrate that wavelength-selectivity could be used to dynamically pattern hydrogel multimaterials, we formulated multilayered hydrogels composed of distinctly patterned regions of Rubiq, Rubpy, and oNB using open-microfluidic additive manufacturing methods . These multifunctional hydrogels were sequentially exposed to red, green, and blue light, and imaged using digital photography (Fig. ). Following red light illumination, Rubiq exhibited the pinkto-purple color change observed previously to accompany degradation, while Rubpy and oNB were visibly unaltered. Treatment with green light caused Rubpy to lose its yellow color and degrade, leaving only oNB regions intact. Final treatment with blue light yielded complete material dissolution. Exploiting conventional photolithographic methodologies, whereby homogenous gels were exposed to collimated light through a chrome photomask, patterned hydrogel degradation was achieved with high spatial resolution (Fig. ).