In view of the above, the work involved the preparation of new PBS-DLS composites with the addition of hydroxyapatite using twin screw extrusion and injection moulding techniques. A comparative analysis of the physicochemical and mechanical properties of two series of materials differing in the size and shape of the HAp filler particles was carried out. Nanometric hydroxyapatite with irregular filler grain shape and micrometric hydroxyapatite with needle/whisker shape were used for the investigation. This is the first time such an analysis has been reported for PBS-based materials.