It is important to identify Young's modulus, which is a parameter of force. Young's modulus was measured from different directions. First, nanoindentation was performed on the wide face of all plate-shaped crystals, measuring the Young's modulus in the thickness direction (Table and Supplementary Figure ). Comparing the crystals of compounds 1-3 and 4-6, the Young's modulus of compounds 1-3 was larger (Figure ). This result is consistent with the prediction by LASSO because most of the dataset used for LASSO regression consisted of nanoindentation results and these crystals are thought to reflect the intermolecular interactions included in that dataset. However, halogenated crystals (compounds 7-10) did not align with predictions. Crystals of compounds 7-9 had relatively large Young's moduli. This is because the dataset includes halogenated crystals that form halogen bonds with relatively small Young's moduli, while halogenated crystals in this study does not form halogen bonds. For example, hexachlorobenzene, which is known for plastic deformation , has a relatively small Young's modulus in the dataset and contributes to a negative relationship in the regression because it has six halogen fragments.