The QED measurement relies on empirical reasoning, which considers the distribution of various molecular properties. These properties include molecular weight, LogP (partition coefficient), topological polar surface area, the count of hydrogen bond donors and acceptors, the number of aromatic rings and rotatable bonds, as well as the presence of undesired chemical functionalities. By taking into account these diverse factors, the QED measurement offers a comprehensive evaluation of molecular quality and desirability as potential drug candidates . The complete weighted QED equation from the original development , where W represents the weighting for each respective desirability function, is as follows: