Given the importance and broad application of amide molecules in the textile and pharmaceutical sector, we also examined our standard protocol in the preparation of amide products from various ketones (Table ). Notably, an array of aliphatic ketones such as (1d-2) and (1d-8) underwent our protocol smoothly giving the corresponding amide products above 85% yields. Phenylacetone with different substituent groups (1d-4, 6) also worked very well. Interestingly, the yields of amide from the transformation of p-methyl substituted and o(p)-methoxy-acetophenone (1d-1, 3 and 7) and naphthophenone were very well, in comparison, the yields of amides obtained from the transformation of o-methyl substituted acetophenone (1d-9) and 3,4-methylenedioxyacetophenone (2) were relatively lower but still satisfactory. Probably owing to the steric hindrance effect, the transformation of paramethyl-substituted acetophenone (1) generated corresponding acetanilide with a higher yield (93%) than orthomethyl-substituted acetophenone (9) (55%). However, due to the more important electron-induced effect, the conversion of ortho-( ) and para-methoxyl-substituted substrate (3) obtained the target products in a similarly high yield (above 90%). As well as the same reason is true for the lower yield of the conversion of para-chlorine acetophenone (1d-5). Table Scope of aromatic, heteroaromatic, and aliphatic aldehydes a a Reaction conditions: General procedure B: 0.5 mmol aldehydes, 0.75 mmol NH2OHHCl, 0.1 mmol triphosgene, 4 mL MeCN, 80 C, 4 h. Conversion and Selectivity were determined by GC/ 1 H NMR spectroscopy.