To encode molecules and reactions for visualisation, we evaluated two reaction fingerprints to convert molecular structures into numerical representations, which are ECFP, and reaction bidirectional encoder representations from transformers fingerprint (BERT FP). ECFP is a topological molecular fingerprint to convert the circular structure of neighbourhood of each non-hydrogen atom into bytes. In this work, the radius of the fingerprint was three (ECFP3), which detected the multiple layers of the neighbourhoods from the molecule centre, and all molecules were converted into 256 fixed-length bit string to reduce the chance for bit collision. To represent the enzymatic transformation via a reaction, the ECFP3 of reaction product was subtracted with that of substrate to create 256 bits as the reaction fingerprint.