Combination of DataWarrior evolutionary docking, ligand efficiency estimations, and ADV consensus docking, identified a few chemotypes predicting low nanomolar docking-score ranges targeting known FtsZ cavities. Additionally, further in silico predictions of the viability of chemical synthesis of each out-ligand chemotype may help to filter those candidates before chemical synthesis for experimental assessment. The results remain to be confirmed by new docking algorithms (additional consensus docking) with improved force-fields , and in vitro/in vivo binding to FtsZ before physiological and pharmacological tests. The parent molecules were selected from fragments of PC190723 from Figure . Common DW+ADV leads were identified from the rectangle areas of DW22 and DW23 (Figure , gray rectangles).The children lead number were automatically assigned by DW as ordered by their generation during the evolutionary library building. Similar lead structures were tabulated with the same background colors.