be achieved at low P-factor. This inverse proportional behavior makes sense, because at low reaction severity native lignin rich moieties, such as β-O-4, are broken down to a lesser extent. The S/G ratio, which is important for specific high-value lignin applications, follows trends similar to those observed for the β-O-4 content. We find the highest S/G ratio at low process severity, which is likely due to the higher reactivity of S-units in lignin fragmentation and therefore their predominant release during the initial stages of the AqSO process. As expected from our previous work , we observe the highest carbohydrate content, corresponding to LCC moieties, at low severities where the formation of new LCC linkages is more favorable than the cleavage of native LCCs. With increasing process severity, the equilibrium shifts to the degradation of LCCs, both due to cleavage of the linkages between lignin and carbohydrates as well as the degradation of carbohydrates (mainly xylan) themselves. We see that the predicted carbohydrate content fluctuates between 0 to 30 units per 100 Ar several times as the P-factor increases under moderate temperatures. This behavior can be an indication of a larger measurement noise at lower P-factors than initially assumed for the carbohydrate content. Surrogate model landscapes are thus not only useful for predictions, but can also highlight issues with the experimental process.