In this study, we have examined the initial nucleation of iodine species such as HIO 3 , HIO 2 , I 2 O 5 , and I 2 O 4 together with atmospherically relevant acids and bases such as sulfuric acid, nitric acid, formic acid, ammonia, dimethylamine, trimethylamine and water. We have explicitly included all relevant iodine oxide-water clusters, that are equivalent to the incorporated iodine oxyacid clusters, such that the hydrolysis reactions of the oxides can be incorporated in future studies. Building upon the set of cluster structures from our previous study, we find that halogen bonding through the formation of I-O bonds is still the most favored type of bond.