The large number of relevant markers present in the Biomarker Insights dataset 106 are captured from research articles spanning the last 7 years. To assess promising markers within these, a scoring of the diagnostic and risk markers is required in order to prioritize the ones which can be considered for further validation and diagnostic application. A validation score is calculated for each of these markers based on 5 contributing factors. These factors are weighted according to their relative value in determining biomarker-disease association: