Pre-prepared compounds were next collected into Schrödinger Phase databases for use during docking and future studies. Coordinates were stored in the compact internal coordinate representation, and a single conformation was generated with rapid sampling from each input compound during the Phase revise step. To enable parallel processing within the CSC system wall time limits, the 20 input files were further split into a total of 781 individual Phase databases of approx. 4.8 million compounds each.