Next, we transitioned this methodology to our engineered flow system. One crucial aspect of this strategy is the electronic density on the nitrogen atom. Trifluoromethylamino anions are prone to undergo α-defluorination when there is an excessive electronic density on the nitrogen atom. To mitigate this decomposition pathway while maintaining optimal nucleophilicity, we employed 18-crown-6 in conjunction with our precursor. This approach enables the complexation of the cesium cations, thereby preventing their interaction with fluorine atoms and stabilizing the desired anionic species. Thus, flowing a solution of the imidoyl dichloride 1 and 18-crown-6 ether (1 equiv) through a cartridge filled with CsF reduced the generation of the NCF3(Ts) anion to just 7 minutes.