The objectives of this study were (i) to elucidate the drivers governing the environmental and economic viability of the NEWgenerator, and (ii) to prioritize opportunities to advance system sustainability through targeted improvements and prioritized deployment of the technology. To this end, we used a quantitative sustainable design (QSD) approach to characterize the technological, economic, and environmental sustainability of the NEWgenerator technology. Our analysis leveraged detailed design and published performance data from a field trial in an informal settlement in South Africa over a 534 day period (October 2018 to March 2020), treating highstrength blackwater and yellow water from a community toilet facility. In addition to the NEWgenerator, the analysis included a frontend (user interface such as a urinal and squatting/seat pan and associated plumbing), pretreatment, a foundation, and onsite sludge treatment to simulate fully operational NSS system. We evaluated the system using QSDsan, an open-source, community-led platform for the QSD of sanitation and resource recovery systems.