To detect the Schistosoma which absorbs visible light, Isaac I. Bogoch et al. ( ) designed a smartphone-based detection system which can detect particle diameter as small as 0.87μm. The basic structure of the system consisted with a smartphone and an external lens, which indicated this paper that with the help of external lens, micron-sized particles could be easily detected. To detect viruses that do not absorb visible or UV light, Zeying et al. ( ) designed a printed dielectric nanochain assay, which gave this paper a good idea to detect the third kind of particles. To solve the unobservability of this kind particles, Zeying combined specific viruses and observed nanochains through specific antibodies embedded on the surface of the nanochains, which allowed the combination to be detected. In conclusion, a series of studies have shown that detection systems based on commodity digital cameras can accurately detect chemical particles at the micron or even nanometre scale, and it is also a fast, efficient and low-cost method for chemical particle detection. In addition, most of the current research on commodity digital cameras microscope imaging systems focuses on the situation where the sample to be detected is in solution, while in real life there are many scenarios that require direct detection of solid surfaces, such as rapid detection of coronavirus on floors, door handles, etc. Therefore, more research is needed to focus on how to directly detect the chemical particles on the solid surface, or how to transfer the particles on the solid surface to the solution or test paper for accurate detection. absorption. For those substances that do not absorb the two kinds of light, the analyte can be pretreated to have the absorption properties. Therefore, two kinds of samples were designed in this project, visible-light-absorbing samples and fluorescent samples.