At present conventional enterovirus detection instruments, such as electron , light or fluorescence microscopy , and methods, such as polymerase chain reactions (PCR) or microtiter plate-based enzyme-linked immunosorbent assay (ELISA) , are not always practical for clinical settings. This is because traditional instruments and methods are often uneconomical, require extensive training to correctly operate and are time consuming, such that they do not meet the requirements of a typical doctor-patient consultation (< 10 minutes) . Microtiter-based ELISA have demonstrated breakthroughs in the field through the detection of plant viruses and have been advanced for clinical settings through the development of lateral flow assays, which prove to be economical, simple and rapid . An excellent example of where ELISA-based lateral flow assays have been widely implemented include the ubiquitous pregnancy test . However, ELISA which utilises antibodies to detect analytes of interest are restricted by their potential to detect small molecular weight targets and variable biosynthesis methods . Bearing this in mind efforts have been directed towards the development of rapid, accurate and economical point-of-care viral biosensors that capitalise on innovative detection mechanisms could be used to stratify individuals presenting with the symptoms of a virus infections.