Although there have been numerous efforts to explore the predictive capabilities of models, there are several barriers that limit widespread adoption in the field of predictive proteomics. First, there are substantial difficulties in accessing datasets in a suitable form for ML applications. A substantial amount of effort is required to prepare raw proteomics datasets into a usable form, requiring expertise in proteomics data processing and intimate knowledge of the many post-processing methods available. Recently, tools such as ppx and MS2AI 9 were created to facilitate this process, but they are still limited to certain use cases due to the complex nature of LC-IM-MS data.