The isosteric enthalpy of H2 adsorption (∆Hads, which, although discouraged, is also sometimes referred to as the isosteric heat of adsorption, Qst) can be calculated by collecting adsorption isotherms at multiple temperatures and applying the Clausius-Clapeyron equation. Briefly, the logarithms of the pressures that give a specific adsorbed amount of H2 at certain temperatures are plotted against reciprocal temperatures to obtain ∆Hads/R as its slope, where R is the gas constant. The pressure that gives a specific gas loading at a given temperature is often determined using the Langmuir-Freundlich model. The best practice for using that Clausius-Clapeyron analysis is to use a narrow temperature range (10-40 K), because a temperaturedependence of the isosteric enthalpy of adsorption can arise. However, our experiments revealed that the H2 binding strengths for Cu I M-MFU-4l frameworks vary widely, prohibiting use of the same temperature range for all three frameworks in a holistic Clausius-Clapeyron analysis.