The QM-based analysis encoded in the first-order coupling trees in Figure is consistent with H-14 having six coupling partners, forming an array of relatively closely matched coupling constants. This leads to a dddddd-type pattern consisting of 2 5 =32 individual lines. The line frequencies are so close that, when combined with experimental or natural line width, a highly complex set of peaks results, which overlap to what would typically be called a broad singlet that coincides with the one peak of the H-14 dd pattern located in the 2 nd quadrant. As QM-based full spin analysis considers the entire J-coupling network of the molecule, an accurate description of all patterns including that of H-14 is achieved (see HiFSA profile, Supplementary Material).