Even at a lower printing temperature, the viscosity of the melted blend is lower than that of the neat polymer. Importantly, no major change in viscosity was observed during isothermal heating. Apparently, potential degradation of the drug does not have a marked influence on the viscosity of the blend, and therefore also not on the printing process. Nevertheless, degradation of the drug after being heated to 140°C in the printer for several hours could be verified by H NMR measurements (Figure ). A possible degradation mechanism induced by thermal treatment is for instance decarboxylation. The MEW printed scaffolds were analysed by DSC and PXRD to ensure the amorphous state of the drug (Figure ). As already mentioned before, the signal to noise ratio of the PXRD patterns makes it difficult to exclude minute crystalline components, especially since the diffractograms of polymer:IND scaffolds show more noise than those of the neat polymer.