Compounds 6-10 exhibited different interesting biological activities. For instance, nigrosporin B (6) displayed modest anti-mycobacterial activity , phytotoxic activity , and potent antibacterial and cytotoxic activity . Also, 4-deoxybostrycin showed modest antimycobacterial activity , potent antibacterial activity , and moderate antitumor activity . Nigrosporin B (6) and 4-deoxybostrycin . Compound 8 displayed significant antibacterial activity against the Gramnegative bacteria; E. coli (MIC value of 6.25 µM), V. anguillarum (MIC value of 1.56 µM), and V. parahemolyticus (MIC value of 12.5 µM) . Additionally, it exhibited potent activity against M. tuberculosis with an MIC value of 12.50 µg/mL and was also active against Plasmodium falciparum with an IC50 value of 7.94 µg/mL , (Figure ). Aspergillus was the richest source of marine anthraquinones and their derivatives among all marine-derived fungi with 73 reported compounds including the previously mentioned 7, 8, and 10 as well as other seventy anthraquinones . For instance, thirteen compounds (11-