The modern synthetic chemist has a wider range of techniques at their disposal than ever before for developing synthesis routes to complex molecules. These technologies drive innovation in advanced materials, agrochemicals and life-saving drugs, allowing products to reach the market in timelines that were previously thought to be unachievable. Developed manufacturing processes, particularly for the synthesis of active pharmaceutical ingredients (APIs), must consist of a scalable reaction, but also control strategies and analytical methods to ensure suitable product quality. Modeling and simulation play an increasingly important role in development workflows, granting a holistic and data-rich overview of the system in question.