The distribution of metal coordination number is essentially the same between the two datasets, so this shift likely indicates that there may be some bias in the K-C2 dataset towards MOFs with more interconnected SBUs where the metal-coordinating atoms are bonding to more atoms (Supporting Information Figure ). Noticeably different distributions are also observed for RAC 𝑍 ! " #$$ %& , the average difference in the nuclear charge between the metal atom and atoms that are one bond away (Figure ). Differences in distributions for this RAC can likely be correlated to differences in the overall electronic environment created by the SBU. This RAC feature shows a much broader tail in the CoRE dataset than the K-C2 dataset, suggesting that the metal coordination space in the K-C2 dataset is underexplored relative to the broader MOF chemical space exhibited in the CoRE MOF set (Figure ).