The selection of drug combinations that are applied to the model in different ways. In the common model for the Loewe-Additivity model, the graphical representation looks like Figure where two drug compounds have a predicted synergy if they interact with a common target. In Figure , the network is created for the drug-target combinations. This network shows that there are 132 edges and 161 nodes. This shows what kind of connectivity there is with a well studied model like the Loewe-Additivity model. This yields 328 drug combinations that are possibly synergistic.