DNA computation, alternatively referred to as biomolecular computing, investigates the utilization of DNA molecules as a foundation for computational processes. DNA molecules, with their ability to store and process information, have been proposed as a potential alternative to traditional electronic computers. The fundamental concept driving DNA computation involves harnessing the inherent properties of DNA molecules to perform particular computations. DNA molecules are made up of four basic building blocks, called nucleotides, which can be arranged in different sequences to encode information , . Following Adleman's proposal of DNA computation in 1994, which depended on the thermodynamic equilibrium of base pairing and successfully addressed the Hamiltonian path problem , and later, the significant advancements in merging digital logic with DNA molecules to construct DNA logic gates, as demonstrated by Okamoto et al. , Caltech and IBM scientists, in 2009 , used self-assembled DNA scaffolding, based on DNA origami, to build tiny circuit boards, on surfaces that were compatible with today's semiconductor manufacturing equipment.