When lysozyme is used as a scaffold for gold NCs instead of BSA (Fig. ), the number of Au atoms in the protein ranges from 1 to 5, thus significantly less than what was observed for BSA. The number of gold atom in protein is correlated to the size of the protein template from BSA (607 amino-acid residues) to lysozyme (only 130 amino-acid residues). While the max peak position seems similar, the width of the distribution for Lysozyme-AuNCs is found to depend on the matrix.