Despite its lack of HSR induction, alachlor exposure increases DNAJB8 affinity of many more proteins than acetochlor exposure (Figure and Figure ). 764 proteins show significantly (q-value < 0.05) increased DNAJB8 affinity following alachlor exposure, as opposed to 81 proteins following acetochlor exposure. Selectively targeted proteins included Microtubule Associated Serine/Threonine Kinase Like (MASTL) (fold change = 2.02, q value = 5 x 10 -5 ), a kinase involved in mitosis , and Zinc Finger Protein 24 (ZNF24), a tumor suppressor . The higher impact of alachlor as opposed to acetachlor is in some ways surprising, as the two molecules are isomers differing only by a methyl group. However, regioisomers can have substantially different lipophilicities and cellular uptake . Alachlor has a log Kow of 3.5, as opposed to 3.0 for acetachlor.