to each hydrogen and carbon atom, assisted by a combination of two-dimensional homo-and heteronuclear NMR: COSY, HSQC-DEPT, and HMBC. The assignment of labile H-N hydrogens in 1 H NMR spectrum is of particular interest in aqueous media, where such labile hydrogens could be potentially affected by intermolecular interactions (e.g., hydrogen bonding) with co-solvated constituents. Peak splitting patterns and corresponding n J H-H , n J H-F , and n J C-F coupling constants observed in each assigned spectrum have been jointly discussed, and n J C-F coupling constants were compared to those taken in DMSO-d6.