Varying the hydrophilic blocks to polymers with different chemical moieties responsible for the hydrophilicity could therefore help to improve our understanding of the underlying self-assembly mechanism. In this context, a comparison to PEG is particularly desirable, as the hydrophilic POx and POzi polymers pMeOx, pEtOx and pMeOzi have all been discussed as alternatives to PEG in a variety of applications. However, PEG/pPheOzi-based copolymers are not readily accessible due to their different polymerization mechanisms.