Overall, these findings provide a practical guide for selecting model chemistries that optimize both accuracy and computational expense based on the target species. By selecting and combining suitable options for geometry optimizations, single-point energy calculations, along with appropriate energy correction schemes including AECs and BACs, users can achieve reliable ∆H • f values for a wide variety of small organic molecules. As more highaccuracy reference data become available, especially for underrepresented ionic and high-spin open-shell species such as zwitterions and triplets, the potential benefits of specialized AECs and BACs for these classes of molecules will likely increase. Moreover, extending these energy correction protocols to larger, biologically relevant molecules and solvated phases present a promising avenue for further advancing the accuracy and applicability of computational thermochemistry.