As RADA16-I is a peptide there is a possibility of covalently elongating it with different bioactive peptides without, to any great extent, disturbing its gelation properties. Successful modifications that have incorporated different peptide epitopes to the RADA16-I sequence while maintaining its gel properties are not only the short four-aa chain peptide RGDS, designed for periodontal therapy , but also longer 14-aa chain peptides such as TAGSCLRKFSTMGG, which has been applied for enhancement of endothelial cell adhesion .