Our attention then turned to investigating the properties of the new cage. First, the solubility of CC21 was investigated since the flexibility and size of the isopropyl groups on the periphery would potentially increase the disorder in the bulk packing and improve the solubility compared to other previously studied structurally analogous POCs. Although imine cages are inherently solution processable due to their discrete molecular nature, they generally have quite low solubilities. The solubility of CC21 in CHCl3 was found to be slightly lower than CC13, the most soluble derivative of these cage analogues found to date (165 vs. 200 mg mL -1 , respectively), but this is still a drastic improvement over most of the CC-family (for example, CC3 has a solubility of 9 mg mL -1 in CHCl3), suggesting it may be suitable for applications requiring high solubility such as porous liquids. Solvated crystals of chirally pure CC21-R that were suitable for single crystal X-ray diffraction (SCXRD) were obtained by slowly diffusing MeOH into a solution of CC21 dissolved in CHCl3. In the solvated crystal structure, CC21•CHCl3•MeOH, the packing of the CC21 cages is frustrated by the isopropyl groups on the cage vertices, which creates extrinsic voids that are full of disordered solvent molecules.