Additionally, a relatively large standard deviation among six runs is observed in the benchmark case. In the augmented case, 44.6% of elite molecules contain at least one ethylene group, and 28.4% have at least one ring group. In other words, the fragment library in 540 the augmented case facilitates the construction of, on average, 108 candidate molecules that can never be identified in the benchmark case. These also include the two best-performing candidate molecules.