In the Q/s approach, automated sampling generates many of these isomers, with all of them (and potentially more) appearing during MD sampling. However, tracking every possible isomer from the trajectory is infeasible. Instead, by using interaction-pattern conformers, which will generally encompass various minima in the Q/s approach and multiple configurations in the C/d MD sampling, we establish a common descriptor to classify configurations and enable a meaningful comparison of their populations with both methodologies.