FLPs catalysis provides another transition metal-free approach to the activation of dihydrogen. The FLPs-catalyzed activation usually needs a mild condition. In addition, FLPs catalysts exhibit better chemical selectivity, stereoselectivity, and asymmetric selectivity. However, as a new field of catalysis, there are still some limitations and challenges, (e.g., the reactions do not have a good chemical selectivity, which limits the application of FLPs catalysis in the synthesis of complex molecules). In addition, the variety of FLPs still needs to be expanded since it is still a relatively new method of catalysis.