In a separate vial, 5 (0.050 g, 0.23 mmol, 1 eq) was dissolved in 1,1,1,3,3,3-hexafluoro-2propanol (HFIP) (200 µL) and added dropwise to the first microwave vial. The mixture was then heated to 80°C for 24 hours. It was then cooled to room temperature and quenched with 1 mL of DI H2O. The mixture was transferred to a separatory flask and diluted with 20 mL DCM and 20 mL 1% aqueous HCl. The organic layer was collected and the aqueous layer was again extracted with 20 mL DCM. The combined organic layers were then washed with saturated NaHCO3 and brine sequentially. The organic layer was dried with MgSO4, filtered, and concentrated on rotavap.