For the isolated eb-MBE(2), it amounts to about 10 kJ/mol per water molecule (for B3LYP/DZP). This error is reduced to ca. 6 kJ/mol when using point-charge or frozendensity embedding. The db-MBE(1) provides an accuracy that is comparable to the eb-MBE(2), and with the second-order db-MBE(2) the error per water molecule is reduced to ca. 2 kJ/mol, i.e., well below the threshold of chemical accuracy (1 kcal/mol) for the interaction energy per fragment.