Simulated systems SDS micelles in water without peptides were simulated using Amber parameters from Amber-Tools 24 and CHARMM36 26 parameters from CHARMM-GUI. Following the electronic continuum correction (ECC) to implicitly include electronic polarization, atom charges were scaled by factor 0.75 in Amber simulations and compatible ion parameters were used. Amber simulations were ran with TIP4P 27 and CHARMM36 simulations with TIP3P 27