DNA nanotechnology is experiencing rapid growth and utilizes deoxyribonucleic acid (DNA) as a primary tool to create artificial structures suitable for numerous diverse applications. Manipulating DNA, which is a well-defined structure with a diameter of about 2 nanometers and a helical pitch of about 3.4 nanometers per turn, outside of its biological environment to develop, investigate, and apply DNA-based structures has resulted in the possibility of taking advantage of DNA's chemical and physical properties at the nanoscale. This has led to remarkable progress in controlling molecular self-assembly and revolutionizing nanoscience, and nanotechnology. The diverse use of DNA in biological areas, such as disease prevention, antitumor drug delivery, diagnosis, bioimaging, biosensing, tissue regeneration, and inflammation inhibition, has been fueled by advances in DNA nanotechnology , , , .