Commonly targeted biomolecules in blood include hemoglobin (Hb) from red blood cells (RBCs) and genetic material from white blood cells (WBCs). Spectroscopic techniques, such as Raman 7,24-28 , infrared 8,29-31 , reflectance and UV-Vis absorbance spectroscopies have all probed the timewise degradation of Hb. Photography and hyperspectral imaging have measured the colour changes in blood while electron spin resonance and electrochemistry analyzed the conformational changes of the heme groups . Atomic force microscopy has investigated the changes in RBC physiology over time while mass-spectrometry , chromatography and fluorescence spectroscopy have measured changes in metabolites and protein composition of deposited bloodstains. DNA , total RNA, mRNA and miRNA degradation have also been targeted in longer time series. Recently, microbial profiling of bloodstains has described the timewise changes in microbial communities inhabiting the bloodstains . Some studies have even attempted to determine the time of day of deposition by evaluating circadian biomarkers and the age of the donor by examining changes in methylation or signal joint T-cell receptor rearrangement excision circles .