Values reported are the contact enrichment average over time with its corresponding 90% CI in square brackets. Further information about this method can be found in the SI. (b) Difference between the time average polymer-protein contacts per amino acid between the peptides within the core and at the core-corona interface. A positive value corresponds to more contacts between a specific EEK residue and either a polymer bead or water at the center of the core than at the core-corona interface, and vice versa for a negative value.