Most LLC particles are fabricated using high energy shearing methods like probe sonication. In addition to associated costs, health risks, and batch-to-batch variability, this method can have a profoundly adverse effect on delicate biomolecular cargo, requiring encapsulation/loading steps to be performed post-formation. To explore the potential of this on-chip method to both produce and simultaneously load LLC nanocarriers, two assays were included. A dye was used in each, curcumin (hydrophobic) in the first, drawing from an excellent recent paper by Chang et. al., and carboxyfluoroscein (hydrophilic) in the second.