Our docking results indicate that 9d engages the catalytic tunnel and binds to the zinc ion in a bidentate fashion. The linker is sandwiched between F150 and F205. Notably, the iso-propyl-phenyl moiety of 9d occupies the cavity above the L2 loop, while the cyclohexylamide points in the opposite direction with no specific interactions predicted. ). The zinc ion is shown as a cyan sphere.