The timewise analysis of the computational effort showed that CTY-TAD is more efficient in finding reactions than PESmapping, as it found more reactions in less computing time. The primary reason for the inefficiency of PESmapping is that non-reacting simulations take up the major part of PESmapping's computation time. In addition, almost half of the exploration tasks completed by PESmapping resulted in the same reaction (R1). These limitations can become a considerable bottleneck in applications where computing time is a limiting factor but can be addressed by reducing the simulation timeouts, thus reducing the non-reactive idle time.