Framework isomerism is interesting to examine in detail, either considering each individual isomer or collectively, as it has been found to influence properties such as flexibility and adsorption. Conformational isomerism is reported to impact the collective flexibility in DUT-8, a MOF with Ni 2 paddlewheels, dabco pillars and naphthalene dicarboxylate (ndc) linkers. In recent work by Petkov et al., by using DFT calculations they observed the wine-rack movement of the stable isomers of DUT-8 originated from the long-range orientation of the linkers, which may point "up" or "down" relative to each paddlewheel building block. They discovered that the isomers possess different energy barriers to transform from the open form to the closed form, which results in reduced flexibility in one of the isomers. The energy barrier difference arises due to the different relative alignment of the naphthalene building blocks.