The usage of QCr techniques has already proven its utility to understand the electronic properties and bonding attitudes in other HP materials . In the case of annulene , the analysis of the electron and current densities, combining experimental and computational methods, has shown that the compound's aromaticity could be partially suppressed by applying an external compression (~ 8 GPa). Further, the elusive behavior of metallophilic interactions as a function of pressure has been investigated in two isostructural copper and silver coordination polymers through XRD and theoretical topological analysis, showing that Ag + -Ag + bonds could be triggered by compression, but not Cu + -Cu + , shedding some light also on the role of relativistic effects in these weak interactions . On other occasions, QCr was used to understand the pressure dependence of the magnetic interactions in metal-organic systems, combining accurate X-ray and neutron diffraction measurements with quantitative modeling of the electron density using spin-polarized DFT . Similarly, Scatena and coworkers , have investigated the orbital reordering, magnetic changes and Jahn-Teller distortion switches in Cu 2+ -based coordination polymers and perovskites as a function of pressure using in-situ HP X-ray diffraction. Also, the symmetrization of polyiodides in CsI3 under compression was elucidated thanks to the synergistic cooperation of X-ray diffraction measurements with quantum chemical computations.