It is important to acknowledge that polymer degradation processes might involve more complex mechanisms, such as repolymerization, that are not fully captured by our current approach. While kinetic data from literature sources may be more accurate within the specific systems they were derived from, their applicability to broader problems could be limited by systematic errors that are specific to certain experiments or laboratories that limit data pooling. The systematic approach taken with the alkane kinetics dataset is ideal from a computational perspective, but it can only only be applied where mechanisms are already established. Automated reaction exploration algorithms could assist in this regard, but have yet to be explored for this problem. Until advancements are made in calculating kinetic degradation data across a broader chemical space, simpler approximations like minimum bond dissociation energies, are preferable. Future research should focus on incorporating more complex polymer-specific degradation mechanisms into the predictive models.