Isotopic labeling with N has a myriad of useful applications in a variety of different contexts due to its low abundance in nature thereby aiding analytical detection (NMR, MS, and MRI). To be sure, the incorporation of N labels can aid in food safety analysis and nutrient metabolism research, the study of organic and organometallic mechanisms, structural biology, biogeochemistry, and in chemical biology pursuits. There is a documented need for new approaches to molecules incorporating 15 N without the need for expensive reagents or a complete redesign of synthetic pathways for their preparation. Given the ease with which nitroamide 16 can be prepared, the corresponding 15 N-labeled reagent was prepared from inexpensive NH4 15 NO3 (ca.