3D electron diffraction (3D ED), also known as MicroED, is a crystallographic technique capable of structure determination from micrometre-sized crystals and has been used to determine a number of small molecule crystal structures . Two studies from 2018 highlighted the potential of 3D ED (also known as MicroED) as a phase analysis tool for the pharmaceutical industry by rapid structure determination and solving numerous small molecule structures from an artificial heterogeneous mixture . When collecting 3D ED data, single crystals can be selected from multiphasic mixtures, allowing the crystal structures of individual phases to be determined. Since structure determination can be achieved from just one crystal, phases in nanomolar amounts can also be detected and characterised. Yet, most 3D ED data collection is performed manually and is a time-consuming process. Generally, only a few datasets (10 to 20) are collected over a half-day session, even though there are usually thousands of crystals on the grid, meaning typical sample sizes are inadequate in describing the bulk material for phase analysis and minor phases may go undetected.