Importantly, results of unknown samples as well as results of method validation were additionally corrected by the system contamination with certain compounds that most likely occurred as extractables and/or leachables from the used laboratory tubes during sample preparation and/or the LC instrumentation itself (BPA, BPS, MBP, MEHP, benzyl butyl-/dibutyl phthalate, nbutylbenzenesulfonamide, nonylphenol). This was done by applying triplicate analytical blanks (extracting water) and determining the extent of the contamination via solvent regression.