Implementation of dynamic operation of heterogeneous catalysts requires the capability to modify the binding energy of surface intermediates with time. Based on the simulations of Figs. , catalyst and system parameters should be selected to achieve average turnover frequencies above the optimum of static conditions and preferably as high as resonance conditions. This implies that a physical catalyst system must achieve surface waveform amplitudes of at least 0.3 eV (and preferably above 0.5 eV) and operating frequencies above 10 Hz (and preferably 100-1,000 Hz). These performance targets change with the selected surface chemistry, which will likely have more than two surface intermediates exhibiting linear scaling relationships over a broad range (0.2 < α < 0.8). The complexity of each catalytic chemistry combined with the large number of dynamic catalysis parameters indicates that each system can be guided by the principles proposed here but will require detailed microkinetic modeling for design and optimization.