Since a clear understanding of the effect of GO confinement on water diffusion is of fundamental importance, e.g., to rationalize permeation of molecular species through GO membranes, there is a need for a systematic investigation in particular as far as the amount of confined water is concerned. The present study is addressing this issue by presenting MD simulations for several hydrated GO models with different inter-layer distances and water content. In order to properly describe hydrogen bond formation and dynamics we have chosen DFT based tight-binding theory as a computationally efficient compromise between empirical force fields and DFT (see also Refs. 27,28). The results have been thoroughly analyzed and discussed, in terms of the structural properties, H-bonding, and the diffusion of the confined water. Inspired by the suggestion of a H-bonding network between functional groups of GO by Dreyer et al., we focused on the analysis of potential water bridges that link the GO layers through chains of H-bonds. In fact it is found that these H-bonded bridges provide a key to the atomistic understanding of the slow-down of self-diffusion of water confined between GO layers. This observation is valuable in many applications that includes solid-liquid interfaces such as designing GO membranes for water treatment and selective transport in separation membranes in general.