The compound 4.PF6 (0.3 g, 0.5 mmol) was dissolved in ACN (30 mL), followed by addition of 2-[2-(2-Methoxyethoxy)ethoxy]ethyl Tosylate (0.47 g, 1.5 mmol) under stirring at room temperature under nitrogen atmosphere. The temperature of the reaction raised to 60 o C and then, potassium carbonate (0.2 g, 1.5 mmol) was added along with potassium iodide (0.25 g, 1.5 mmol) to the reaction mixture. Allowed the reaction to stir at refluxing temperature for next 6 -8 hours under nitrogen atmosphere. After completion of the reaction confirmed by MALDI-TOF, the heating is removed and cool down to room temperature. The reaction mixture was filtered off for removing excess of the unreacted salts, filtrate is concentrated under vacuum evaporation. Then dissolved in DCM (200 mL) and washed 2 -3 times with aqueous brine solution (200 mL for each wash). Collect the organic layers and sodium sulfate was added to remove any tiny amounts of water. The organic layer again filtered to remove sodium sulfate and dried by using rotaevaporation. The crude solid product was further purified by using column chromatography (MeOH:DCM, 1:9) and the desired product 5.PF6 is obtained as red-solid powder. Yield = 0.34 g (0.38 mmol, 76%). (m, 2H) ppm.