Another combination that seems unusual at first glance is between chemistry and music. Through sonification, non-musical information can be encoded in the high-dimensional space of music, which humans have accessed with intuition and creativity for thousands of years. A recently developed, novel molecular representation encodes molecules as melodies . The Sonic Architecture for Molecule Production and Live-Input Encoding Software, SAMPLES, combines SELFIES with chemical descriptors into music. This opens the door to applying ML techniques developed for music in the chemical sciences and might help blind people to interact with molecules. The authors showed that using SAMPLES, a new molecule can be generated by interpolating the melodies of two SAMPLES representations, that original molecules can be created from a musical piece played on the piano (although this still requires some knowledge in chemistry and musical theory) and perceive the use of music generation methods as. Most importantly, similar molecules encoded with SAMPLES sound similar and can be differentiated from distinct molecules, showing that their representation obeys the similar property principle, the foundation for similarity-based virtual screening. Thus, combining music and chemistry enables the creative application of previously unusable techniques from different fields of research.