Herein, we have reported a general multiple RTP design principle and validated it using four organic compounds (Cz-C-PTZSO 2 , Cz-CO-PTZSO 2 , Cz-C-TRZ and Cz-CO-TRZ). DFT calculations demonstrated that for sp 3 C-linked compounds, dual RTP could be enabled from both the donor and acceptor fragments, serving as molecular T 2 and T 1 phosphorescence due to the absence of excitonic coupling between two triplet excited states. However, the excitonic coupling channel of T 2 and T 1 is enabled by employing an sp 2 C as a linker between the donor and acceptor moieties, resulting in only one 3 LE emission. Photophysical investigations substantiated this design principle. For Cz-C-PTZSO 2 and Cz-C-TRZ, dual RTP occurs from T 2 and T 1 , which are LE emissions from the donor and acceptor fragments, respectively. For Cz-CO-PTZSO 2 , only RTP from T 1 was observed due to the strong excitonic coupling between donor and acceptor. Benefitting from the multiple intermolecular interactions, molecular aggregate phosphorescence was also activated. However, for Cz-CO-TRZ, there is no RTP, probably due to significant nonradiative decay. Single-crystal and RDG analyses demonstrated that noncovalent interactions influence multiple RTP behavior and TTET. This work provides insight for the design of organic systems that show dual phosphorescence and discloses an effective strategy for designing color-variable RTP that can potentially be exploited in a range of applications.