Mrr-like (IPR039442) is similar to Mrr and contains the (D/E)-(D/E)XK active site, which is present in type II restriction endonucleases. Type II restriction endonucleases, including DpnII, contain restriction endonuclease type II DpnII-like (IPR007637). It recognizes the double-stranded unmethylated sequence GATC and cleaves it prior to G-1. The protein's complete length is present. It is also present in numerous proteins with unknown functions. The DNA adenine-specific methyltransferase domain contains it.