Molecular docking studies were performed with Molegro Virtual Docker software. The first study was a re-docking with the ligand co-cristalizado to validate the method to be used, Figure shows the overlapping structures of the trypanothione co-crystallized in yellow and cyan trypanothione re-docking with an RMSD value of 1.90 Å that being a value less than 2.00 Å allowed us to have a validated method for the docking of the molecules under study.