Increasingly, the potential of multiphase biomaterials combining relatively rigid hydrophobic elastomeric segments and softer hydrophilic hydrogels for a broad range of biomedical applications is emerging. This ranges from advanced in vitro models making use of hydrophobic elastomeric structures to compartmentalise and mechanically stimulate soft cell-encapsulating domains to the engineering of tissue engineering scaffolds . Such materials and associated microfabricated platforms are attractive for the study, control and repair of soft-hard tissue interfaces . Although the engineering of thiol-ene based soft hydrogel enabling cell encapsulation, such as gelatin methacrylate systems, has enabled their integration within a broad range of polyesters or silicones , the study of their mechanical integration and adhesion to corresponding elastomers has received relatively little attention.