Based on the manual synthesis and purification of control compounds (Suppl info. 6), we estimate that the human time required to manually prepare an analogue varies between 1-8 working days, depending on the number of synthetic steps and purifications (Table ). If the synthesis of the complete library was conducted in a linear fashion this would take about 25 years to complete. Although significant time reductions can be achieved by techniques such as parallel synthesis, bulk preparation of common intermediates, and increasing the number of chemists, we still anticipate that a project of this magnitude would take years to complete. In contrast, our platform was able to complete the work in a few weeks with a single trained chemist.