Water catalyzed reaction generation. In previous work we have described an algorithm for including water in the TS search to assess whether proton shuttling can be catalyzed. Here, water-catalyzed reaction mechanism(s) were tested for every reaction with at least one hydrogen atom as the reactive atom. The basic principle is to introduce an additional water molecule as a proton shuttle that may relax the transition state geometry and reduce the activation energy. The procedure for characterizing the water-catalyzed reaction mechanisms is the same as in our previous study, including updating the bond breaking and forming information via the bond-electron matrix, converting 2D reaction representations into 3D reactant-product geometries through a joint-optimization procedure, and applying the reaction conformational sampling algorithm to generate up to five reaction conformations, The Cb3f3 elementary reaction type may enumerate reactions that involve up to two reactive hydrogen atoms. For reactions with a single reactive hydrogen atom, there is only one possible catalyzed reaction mechanism. For reactions with two reactive hydrogens, two water-catalyzed mechanisms are possible. In these cases, all watercatalyzed mechanisms were characterized that were consistent with a given reaction.