Our goal was to intercept some of the endgame chemistry developed for the GLP delivery and showcased in this manuscript. 4-Methyl-7-morpholinopyrido pyridazin-1(2H)-one 10 was a suitable candidate devoid of the storage issues of chlorophthalazine 6. With compound 10 as target, it was envisioned that installation of the morpholine at an earlier stage would negate the need for a methoxy protecting group. Relying on the strong directing group properties of the morpholine substituent and the substitution pattern of our pyridine core electrophilic bromination was expected to occur with great selectivity at the desired position. Halogen-metal exchange followed by trapping of the organometallic species with an acetyl source would prime the resulting pyridine 17 for a facile condensation with hydrazine to afford phthalazinone 10. The retrosynthetic analysis is shown on Scheme 3.