For Lysozyme, TORO's performance closely mirrors XGandalf's when considering parameters such as redundancy, I/σ, and CC 1/2 . TORO indexes ∼ 10% more patterns as XGandalf (Table and Table S1 of SI), which is re-flected by the increased redundancy and a slightly improved I/σ for the low-resolution range. The performance was further analyzed in Figure , showing the subset of frames uniquely indexed by TORO (64845 patterns, dashed black) and XGandalf (17591 patterns, dashed red), respectively. The three metrics demonstrate that the patterns uniquely indexed by TORO add meaningful data to the full dataset. TORO also shows a significantly higher I/σ than MOS-FLM, whereas CC 1/2 is similar for all three indexers.