One choice of drug design using high throughput examinations and computational tools is that it can largely lower the use of animals in activity testing, moreover, in vitro experiments complemented with computational methods have been largely used in early drug discovery to select compounds with more favourable ADME and toxicological profiles naturally, drugs are organic small molecules produced through chemical synthesis, but biopolymer-based drugs (also known as biopharmaceuticals) over through biological processes are becoming increasingly more common.