The marine phoma is representing the most, the greatest and most diverse ecological structure on the planet. Over seven decades, marine natural products (MNPs) have owned credits and been privileged as a robust and sustainable supplier for pharmacologically active compounds that meet a huge interest in pharmaceutical and economical applications. Marine-derived fungi are valuable sources of structurally diverse MNPs due to their various habitats that range from the warm to the colder areas, and even at extreme temperature and pressure like in hydrothermal outlets. One of the fascinating classes of fungal derived natural products is the anthraquinones.