In summary, we have presented a polarizable electrostatic model that is fast, due to its use of the direct polarization approximation, and both general and convenient to apply, due to the use of typed polarizabilities and the AM1-BCC-dPol method of assigning consistent partial charges. We believe that the present work provides the foundation of a generally parameterized polarizable force field that can be used in a wide range of applications in biomolecular simulations.