Very recently, researchers have begun to explore the direct conversion of insulating polymers, such as polyimide (Kapton) and a variety of commercial polymers , to conductive graphenic materials using CO2 laser cutters/engravers. In particular, laser-pyrolized polyimide substrates have been used in a number of biosensing applications, including small molecule detection , protein-based immunoassays , and DNA or miRNA recognition. Laser-induced pyrolysis of cellulose is a comparatively nascent field and to date has been exploited for artistic depictions , simple electric circuits , mechanical sensing , and more recently small molecule detection . Despite early successes, it remains unclear whether cellulose has any advantage over polyimide as a substrate material for laser-induced graphenic electrodes (LIG-Es), aside from biodegradability.