We started evaluating the possible highpressure pathways leading to the formation of a para-H, -OCH 3 cis-functionalized BLG, that we have shown in the previous section to be thermodynamically stabilized at 6.8 GPa. Fig. shows the mechanism and the associated metadynamics-bias landscape at 6.8 GPa, obtained employing the coordination numbers of two Graphene carbon atoms in para configuration as reaction coordinates: one with respect to the interface hydrogen atoms (C 1 -H), and the other with respect to all interface oxygen atoms (C 2 -O).