With the average age of the World's population increasing, the prevalence of age associated diseases including neurodegenerative disorders is increasing as well. Alzheimer's disease is the most common form of dementia and the most common neurodegenerative disease affecting 12% over 65. The major pathological hallmark of AD includes formation of extracellular plaques consisting of amyloid-β (Aβ) peptides as well as neurofibrillary tangles formed by hyperphosphorylated tau protein .