The purpose behind this study is to use RADA hybrids to release small active peptides following elastase digestion at a wound site. To test if such a mechanism is feasible, the in vitro biostability of the peptides was investigated with neutrophil elastase treatment at physiological temperature. Digestion of the peptides was tracked by HPLC, and the released fragments were identified by mass spectrometry. The hybrids revealed the degradation profile presented in The table with all identified fragments are in Supplementary Data (Table )