Based on our docking studies , we identified CHEMBL3120791 which is analogues to Remdesivir, is potential binding ligand molecule on (PDB ID 6m71) SARS-Cov-2 cryo-EM structure of RNA-dependent RNA polymerase (RdRp). We have used GROMACS for molecular dynamic simulation. We have used NVIDIA NGC GROMACS 2020.2 and with of NVIDIA 1080 Ti GPU.