We find that SMARTY is capable of finding SMARTS patterns for the majority of reference atom types For SMARTY for MiniDrugBank, we plot the fraction of simulation time where the partial score is 100% for a given parm99/parm@Frosst atom type. The elements shown here are (a) hydrogen, (b) carbon, (c) nitrogen, and (d) oxygen. We used 10 simulations of 10,000 iterations each to construct the plots at different temperatures (y axis). At high temperatures, most of the reference atom types reach 100% partial score. However, at low temperatures, there are more well populated reference atom types but also more which never achieve 100% at any iteration.