Non-structural maintenance of chromosomes element 1 RING C4HC3-type (IPR014857)In Saccharomyces cerevisiae, this domain may be critical for the Rad52-dependent post-replication repair of UV-damaged DNA. The kleisin part of the Smc5/6 DNA repair complex keeps the C-terminal part of chromosome 4 in good shape (IPR014854). Prior to cell division, the Smc5/6 complex is necessary for the unwinding of the undamaged chromosome and can bind to the damaged DNA strand site. Ku is a prokaryotic-type, non-homologous end-joining protein (IPR009187). The Ku protein is involved in DNA double-strand break repair through non-homologous end joining. In addition to homologous end joining, yeast Ku also plays a role in the structural maintenance of telomeres.