PESmapping together with CV templates has revealed a multitude of oxidation reactions for the three dioxane peroxy radicals. We expect the eight CV templates developed in this study to accelerate oxidation reactions in general. Substantially dierent reaction systems e.g. involving substitutions, diradicals, other chemical elements will need further templates to work with CVHD acceleration. The PESmapping algorithm is independent of the acceleration method employed. At high temperatures, it can without acceleration quickly explore large chemical networks, as shown for butenyl and for the acetylene/phenyl system, which is promising for studying soot precursors and formation pathways.