Alkaline or acidic hydrolysis are used in industrial production to give type A (from pigs, poultry and fish) or type B (from cows) gelatin respectively. Gelatin has a molecular weight between 40 kDa and 90 kDa and is composed of 18 amino acids, with glycine, proline, and hydroxyproline being the major ones. However, gelatin is not robust enough for direct hydrogel applications and usually requires additional chemical crosslinking. Genipin is a glycone, a two membered heterocycle with hydroxy and methacrylate functionality (Figure (a)). Genipin is extracted from Gardenis jasminoides Ellis fruits and can be used to crosslink gelatin. Its low toxicity compared to other synthetic crosslinking agents, about 10 4 times less cytotoxic than glutaraldehyde makes it potentially attractive for biomedical applications. Gelatin-genipin hydrogels have been investigated previously for different applications.