We demonstrate new approach to deliver high levels of nuclear spin hyperpolarization to cistrans photoswitchable compounds comprising azobenzene moiety by utilizing non-equilibrium spin order of parahydrogen. We denote this approach as photo-SABRE. It combines the powerful SABRE hyperpolarization technique and a property of azo compounds to undergo reversible photoinduced cis-trans isomerization. We demonstrate the efficiency of the photo-SABRE approach by hyperpolarizing trans form of azobenzene, known for the remarkable long-lived spin order of 15 N2 nuclei. While cis-azobenzene freely coordinates with SABRE active complex and acquires pH2 polarization, such coordination for trans-form is sterically hindered. Our custom build setup, based on a commercial NMR spectrometer, allowed to conduct experiments comprising simultaneous parahydrogen bubbling at ultralow magnetic field and light irradiation, which results in transfer of SABRE polarization from cis to trans form of azobenzene via photoinduced isomerization. By optimizing experimental conditions, we hyperpolarized 1 H, C and N nuclei of both cis and trans azobenzene. Moreover, we demonstrate the ability of trans- We anticipate that the proposed photo-SABER approach owing to their low cost versatile and straightforward design, robust photoswitching process combined with the long-lived nuclear spin order will expand the scope of the hyperpolarization method to photoswitchable molecules. To conclude, the light-responsive hyperpolarized azobenzene has a potential to become a valuable tool in the already emerging application areas in photopharmacology, photoswitchable adhesives and biodegradable materials for drug delivery. The space between the NMR sample tube and inner walls is filled with a micellar solution for laser beam imaging.