From the electrochemical experiments on a mesoITO scaffold with FDH (52 pmol) at an applied bias of -0.6 V vs. SHE, we observe significant activity in the BC-MES and further enhanced current in the BC-MOPS electrolyte solution (Figure ). As before, repeats of each solution were made and a narrow standard deviation (N ≥ 3) demonstrated the reproducibility of the system. The FEM current density prediction was shown to closely match the experimental results, again confirming the accuracy of the model. The formate production was measured by ion chromatography and displayed a FE of (97 ± 7)% (Figure ) and negligible average H2 evolution with a FE of (0.2 ± 0.2)%, thus demonstrating the excellent selectivity of FDH. The mesoITO electrode without FDH showed minimal current (Figure ).