The conformational ensemble of a molecule can be obtained from its free-energy landscape. Given an accurate Hamiltonian and within the limit of infinite sampling, molecular dynamics (MD) is an established method to generate free-energy landscapes. However, for all but the smallest molecules, this method requires extensive sampling to reach convergence, even when more modern enhanced sampling methods are used. In silico conformer generators forego the limitations posed by sampling methods and use geometric relationships between atoms to swiftly enumerate 3D-structure estimates from the topological graph. When conformer generators are paired with a method to estimate the free energy of resulting conformers, a Boltzmann-weighted ensemble of molecular structures is obtained.