and the electrostatic binding of SPIONs via the portal carbonyl. It resulted in the formation of a hybrid hydrogel with a more robust internal structure compared to hydrogels lacking CB [7] (i.e., dispersion of SPIONs and catechol-functionalized CS) and CB[7]-CS complexes in absence of NPs. Interestingly, thanks to the connectivity among the different components, the responsiveness of the SPIONs extended throughout the entire material (Figure ). Similarly, NPs consisting of a polystyrene (PS) core and a shell made of glycidyl methacrylate (GMA)