To demonstrate the post-synthetic utility of carbamimidate-derived bicyclic aziridines, 2f was subjected to various nucleophilic ring-opening conditions to access diverse alkene difunctionalization patterns (Scheme 2). As expected, 2f underwent facile reactions with fluoride (3), azide (4), and thiol (5 and 5') nucleophiles to exclusively afford the corresponding six-membered cyclic carbamimidate products. In terms of stereochemical integrity, neither dr nor ee erosion was detected. Although we did not attempt to remove the Tces group directly from 2f due to the aziridine's lability, it could be mildly deprotected under reductive conditions to provide an extra functionalization handle with the free amino group. Other post-functionalization pathways, including ring expansions via aziridinium ylides, are under investigation and will be reported in the future.