For the CombiSolu-Exp database, solid solubility data in pure organic solvents are extracted from 105 different literature sources. The temperatures in this database are between 243 and 364K. To compare both methods for the calculation of ∆H diss,T described before, experimental data at a broader temperature range are required. However, for drug-like solutes in organic solvents those experimental data are scarce. For this reason, additional datapoints, for example, for the solid solubility of polyaromatic hydrocarbons in water are collected at higher temperatures in the CombiSolu-HighT-Exp database. The data in the CombiSolu-HighT-Exp database are from 68 different sources for temperatures up to 593K.