In Figure , we present profiles for the DSPC, Dlin-MC3-DMA and Cholesterol lipid components. All DSPC fragments were seen to monotonically increase from the analysis of the outermost surface as profiling was undertaken, although not from zero intensity (Figure ). Adenine representing the RNA core also increased but begins at zero, suggesting that DSPC is present in the shell as well as the core. There is no clear orientation indicated by comparing the headgroup and fatty acid fragments which have similar profiles.