Two factors render the measurement of the Soret coefficient usually challenging: first, the small magnitude of S T and, second, the presence of undesirable convective currents due to gravitation. Despite efforts to produce benchmark data, 21 some even in microgravity environments, the measurement of the Soret coefficient is still challenging, in particular, for liquid mixtures with more than two components. Consequently, several theoretical models were proposed to predict the Soret coefficient, which were thoroughly reviewed, for example, in Reference 16 and 28. However, even the most established models based on non-equilibrium thermodynamics often fail when dealing with strongly interacting liquid mixtures.