The scattering curve of pure A-pPrOzi-A in D 2 O without any added CUR (A-pPrOzi-A/CUR=10/0, Figure , A) shows a flat curve which can be described by the Debye function, indicating a Gaussian chain-like behavior, supporting earlier results, which suggested that this polymer does not form micelles by itself under ambient condition at this concentration (10 g/L). Upon CUR addition, polymer micelles form, as shown by the change in the plateau intensities at low Q-values, and the overall appearances of the scattering curves, indicative of discrete and compact objects. The increasing plateau intensity can be caused by larger particles or a higher scattering contrast. A recent report by Lübtow et al. [23] showed that the hydrodynamic radii of A-pPrOzi-A-CUR aggregates initially decrease slightly at low CUR content (10/0.9: hydrodynamic diameter (D h ) = 26 nm; 10-4.8: D h = 20 nm) and only start to increase at ρ(CUR) > 5 g/L (10/11.9: D h = 46 nm) as determined by dynamic light scattering (DLS). Since DLS measures the hydrodynamic radius, which involves a water corona around the particle, and SANS probes the radius of gyration without this corona, differences are expected. The increasing scattering intensities probably indicate a higher scattering contrast due to the higher CUR amounts, which is solubilized in the polymer micelles. At 50 wt.% drug loading, i.e. same concentrations of polymer and drug, the scattering intensity increases by nearly an order of magnitude compared to the polymer alone (Figure , A and B). The already mentioned DLS results as well as cryo-TEM images have also shown the presence of larger and worm-like particles. These larger structures were also observable by SANS, as the increasing scattering intensities at the lowest measured Q-values indicate (Figure , D). To investigate these particles in more detail, powerlaw or model-based fitting techniques could be used. However, for accurate either their shape and size or the exact ratio between micelles and larger particles must be known. In the present study, we concentrate on the morphological study of the spherical micelles and hence only the corresponding Q-range for single micelles (0.007 -0.3 Å -1