Toward a deep understanding of the electronic properties of the studied compounds, global reactivity indexes were also analyzed. Table also depicts the global indexes considering the chemical potential (μ), molecular hardness (η), and electrophilicity (ω). The maximum hardness principle states that stable systems show resistance to modification on the electron density distribution; ergo, higher molecular hardness is expected. Thus, the studied copper corroles display η values of 0.9 -1.1 eV, suggesting a similar behavior within the studied CuC series. The harder system is the fluorinated case (C1) due to the direct effect of fluorine atoms (as the harder element) over the CuC electron structure. At the same time, the lower η value is found for the alkenyl meso substituents (C7) attributable to the πconjugation of R groups with the CuC core, in agreement with the observed FMOs for this compound (Fig. ). As observed in the last row of Table , the graphene nanosheet presents a considerably lower η value of 0.4 eV, which agrees with the most prominent conjugation on the whole surface, thus, providing a planar structure with enhanced electronic polarization. Additionally, μ is related to the electronegativity χ through μ = -χ; while ω represent the stabilization when the molecular system gains electrons. Hence, μ and ω are related to the relative electrophilic character . With this in mind, the fluorinated alkyl chains in meso positions (C2-C4) display the more prominent electrophilic character due to the electron-withdrawing effect of these substituents. The electrophilic character is also achieved through π-conjugation in C7 due to π-conjugation of the trifluoromethylphenyl substituents, which promote the delocalization of electron density through the whole CuC core.