Further studies on this system are expected to afford their exploitation in physiological media and biocompatible conditions. In fact, solubilization in water with a hydrophilic carrier and in situ delivery has been proven to prevent the expected toxicity of anthracene-derivatives and simultaneously taking advantage of their therapeutic effects. Moreover, for the purpose of hypoxia relieving in a combination therapy regime, both 3 O2 and 1 O2 could serve either as a substrate for PDT or as reactive oxygen species (ROS) itself. Eventually, considering the optical properties of anthracenes, the use of these derivatives could allow not only the treatment of hypoxia to restore the therapeutic performance of commercial drugs, but also the visualization of the readily emitting anthracene derivative for theranostic purposes.