For all these three cases, the constraints and bonds are well modelled with the new coarse-grained parameters and give excellent agreement with the atomistic reference distributions (always below 3% deviation in the average values as shown in Table ). However, when looking at the angle and dihedral angle distributions, in some cases it is evident that there is a larger dispersion CG, grey: AA). Manβ(1→6)Manα was semi-automatically parameterized, and the other two disaccharides followed the fully automated process. For the sake of space, for each monosaccharide modelled as a ring, only 1 constraint (out of 3) between beads that define a ring is shown (first row of each panel-left and right). The harmonic bond between both monomers is presented (middle top row of each panel). All the four defined angles (middle and bottom rows cyan: CG, grep AA), the unique dihedral (green: CG, grey: AA) and SASA (orange: CG, grey: