Consequently, this has to be classified as primarily D-C-only source. By November of 2019 SciFinder reached 157 million unique organic plus inorganic substances, having passed 100 million in June 2015. While some of these are virtual structures (i.e. never been synthesised) this large enterprise (with over 4,500 employees according to LinkedIN) has the de facto largest searchable collection of small-molecule structures extracted from papers, patents and other sources. A presentation from 2016 declared that in the first 7 months of that year ~10.5 million substances were extracted from ~0.5 million patents and ~1.0 million documents. In addition, ~ 75% of current novel structures are from patents . However, the 157 million is exceeded by the latest public UniChem release of just under 160 million . In addition, a 2019 scaffold diversity analysis stringently filtered the CAS collection down to only ~30 million compounds with direct links to literature and patents . Since its first release in 2009 Elsevier Reaxys has emerged as another large-scale D-C capture endeavour, the statistics and search characteristics of which have recently been compared with SciFinder . It has reached 31 million structures but also subsumes PubChem which brings it up to 105 million.