(2) h⊕t,V (z) -∆ t E h⊕t,V as solid curves. These are obtained by subtracting the energy and entropy profiles of the head group from those of DS -for each solvent, V . Also shown are the tail components, ∆ t E t,V and -T ∆ t S t,V as dashed curves. Note that ∆ t E t,V is the average tailsolvent energy for the fully-coupled DS -, ⟨V t,V ⟩ 1 , and shows the tail effect on the binding of DS - to the ACWI. The relatively flat SO 4 CH - 2 free energy, F