Figure shows the distribution of each method for the champion, coverage, and speedup. All methods had a median champion of 1, although random, 3-way and 4-way tournament, and rank selection had more consistent high-performing results. Selecting parents with random selection from the entire population compared to only the top 50% found the champion more frequently and shows a higher median coverage. A possible explanation is restricting selection to the top candidates limits the explorative abilities of the GA. Some monomers found in the poor performers may perform really well when paired with a new monomer, and impeding the GA from selecting these makes it difficult to find all high performers. The selection methods performed similarly for coverage, and all the methods showed comparable outliers. Looking at the individual run performance for champion and coverage (ESI Tables and, respectively), all methods performed worse on optimizing the optical bandgap. ESI Figure shows 2-way and 4-way tournament selection led to worse champions for optimizing the optical bandgap, although performed very well on the other 2 properties. The speedup is also similar across all methods (ESI Table ), with a 3-way tournament selection yielding the highest median speedup. Using ANOVA, comparing methods for the champion, coverage, and speedup show they are statistically indistinguishable (p>0.05).