It is noteworthy that the fluorescence images in Fig. ) and (e) show that CRP was adsorbed on GFETsig, but not on GFETref. This suggests that the antigen-antibody reaction occurred on GFETsig, despite the FET signal being obscured by the noise. In addition, the fluorescence intensity of GFETsig in Fig. was lower than that in Fig. , indicating a reduction in CRP adsorption.