x∈X D q ψ (z|x). In particular, high reconstruction accuracy suggests that (1) for distinct pairs of molecules x ̸ = x ′ from X D , the latent space conditionals q ψ (z|x) and q ψ (z|x ′ ) have mostly disjoint essential supports (i.e., the probability of collisions in the latent space for distinct molecules is low), and (2) for latent codes sampled from the aggregated variational posterior z ∼ q ψ (z|D), the essential support of p θ (x|z, D) should concentrate on a relatively small subset of X D .