Regulation of carbon dioxide has been a paramount topic in relation to control of global warming. Carbon capture, utilization, and storage (CCUS) technologies are rapidly emerging and attract considerable research interest. Conversion of CO2 into bicarbonate or carbonate is one of the methods to store CO2 in aqueous solution. Carbonic anhydrases (CA) can catalyze CO2 hydration and bicarbonate dehydration. 237 Amao et al. developed a bienzymatic system composed of CA and formate dehydrogenase(CbFDH) that catalyzes CO2 conversion at a wide range of pH. Addition of CA promotes the CbFDH catalyzed CO2 reduction to formate in higher pH region (>9.5) conditions. At lower pH (6.3-6.5), CA primarily converts CO2 into bicarbonate. This CA/CbFDH system facilitates CO2 storage at a wide range of pH by alternatively using one of the enzymes.