The RhoGAP domain (IPR037858) is the RhoGAP (GTPase activating protein [GAP] of Rho-like small GTPases) domain present in ARAP. ARAPs (also known as centaurin deltas) are dual GTPase-activating proteins (GAPs) of Arf and Rho family GTPases, containing Arf-GAP, ankyrin repeat ras-associated domains, and a PH structure in addition to the Rho-GAP domain area. Since their Arf-GAP activity is dependent on PIP3, ARAPs are considered to be the integration point for phosphoinositide, Arf and Rho signaling