We introduced CalcUS, an open-source project aiming to make computational chemistry more accessible as well as to save time to more experienced practitioners. It reduces the cognitive load through multiple convenient features and automated processes. We propose CalcUS as a tool in itself, but also as a means of simplifying the use of new software packages and algorithms. For developers, this means a greater accessibility to their tool and more visibility. For end-users, it will result in a seamless integration of state-of-the-art modelling tools into their workflow.