Implicit solvent models simplify the solvent environment by treating it as a continuous medium rather than simulating individual solvent molecules. This approach averages the solvent's effects on the solute, focusing on the macroscopic properties of the solvent, such as its dielectric constant. Because they do not require the simulation of individual solvent molecules, implicit models are computationally less demanding. This allows for faster simulations and the ability to study larger systems or longer time scales with reduced computational resources. While implicit models can speed up simulations and are useful for exploring conformational space, they may lack the detailed representation of specific solvent-solute interactions, such as hydrogen bonding or the precise effect of solvent molecules on the solvation shell of the ligand and receptor .