The Dynamics cross-correlations maps (DCCMs) for the WT, Y493H and C580Y mutants obtained from the entire production dynamics. The black dotted region (residues 350-442) indicates the BTB domain and the zoomed view is shown in panel b. Color Code: cyan color bar belongs to the (positive) correlation, magenta is for anti-correlation and white depicts uncorrelation. In the WT there is correlation within the residue however, significantly increased anti-correlation or uncorrelation in the mutants.