Given the catalytic efficiency of Pd@MOF, we also examined the hydrodeoxygenation reaction scope on a diverse set of biomass derivatives (Table ). The room-temperature HDO performances of Pd@MOF for lignin-derived aldehyde-, ketone-, and nitro-containing compounds, such as vanillin, p-anisaldehyde, 4'-methoxyacetophenone, and nitrobenzene were systematically investigated. For lignin-derived aldehydes, the substrates achieved complete transformation (>99 %). Interestingly, the HDO efficiency and selectivity are only related to the reaction time. In the case of acetophenone derivatives, a relativity longer reaction time is required to completely convert to the desired HDO product (Table , entries 4 and 5). The catalytic performance of Pd@MOF for the HDO reaction of nitroarenes is perfect, its hydrodeoxygenated products, and aromatic amines have been widely used as chemical intermediates for pharmaceutical synthesis. The catalytic activity of Pd@MOF in nitroarenes hydrodeoxygenation was tested (Table , entry 6-8). For nitroarenes containing electronwithdrawing group and electron-donating group, such as -CH3 and -F, above 99% conversion of aromatic amines can be obtained within 3 h (entries 6, 7, and 8 Table ). Again, the superior catalytic activity of Pd@MOF is confirmed by remarkably high efficiency in the HDO reaction of various substrates (Table ).