During recent decades, microextraction has been a central theme within analytical-scale sample preparation research. Resulting from this, various techniques have been invented and research is still very active. One such technique is electromembrane extraction (EME), first presented in 2006 , which mainly has been used for bioanalytical and environmental extraction applications . EME is performed using a supported liquid membrane that separates the sample from a clean acceptor solution. The liquid membrane comprises a porous polymeric membrane, often polypropylene, and a few microliters of organic solvent immobilized in the pores of the membrane by strong capillary forces. Extraction is initiated by applying an external electric field across the liquid membrane, which stimulates charged analyte ions to migrate from the sample, through the liquid membrane, and to the acceptor solution. The latter may subsequently be collected and analyzed by an appropriate analytical method, for example liquid chromatography-mass spectrometry (LC-MS). The organic solvents used in EME are typically non-volatile, non-toxic, and thus safe for the operator. Combined with the very small volume of solvent used, this makes EME a very environmentally friendly technique. EME further offers good selectivity and clean-up of matrix components. Selectivity is controlled by both the polarity and magnitude of the applied electric field, as well as the chemistry and hydrophobicity of the solvent. As such, EME is suitable for extraction of charged analytes across a wide range of properties and hydrophobicity.