These results indicate that GaMD-WE can obtain kinetics involving higher energy regions like α L faster and more accurately than WE alone. In contrast, WE performs as well as GaMD-WE in getting kinetics involving central metastable states, which both methods can sample sufficiently well. In addition, GaMD-WE needs reweighting to have more accurate weights and have an advantage over WE, i.e., GaMD-WE does not necessarily have an advantage over WE from solely covering more of the free energy landscape within the same simulation time. However, this might not be the case if GaMD had covered a region with a higher energy barrier that is difficult for conventional WE to sample quickly, so this hypothesis needs to be tested on more complex systems in the future.