Non-lamellar lyotropic liquid crystalline structures such as the inverse bicontinuous cubic phases have the potential as nanoreactors to enhance the yield of reactions or as templates to produce nanostructured materials with improved physical and chemical properties. The lipid-water interface inside these structures and their ability to host hydrophilic, hydrophobic, and amphiphilic molecules allows the integration of molecules of all polarities into a single phase. The water inside the nanochannels was discovered in various states, from surface-bound to free, with different diffusion dynamics inside these channels. For instance, the interaction of water molecules with the hydrophilic/hydrophobic interface in inverse liquid-crystalline structures was shown to slow their diffusion compared to bulk water. Hence, the modified dynamics and the confinement inside the nanodomains may significantly modify diffusion-controlled reactions such as free