reaction mechanisms that resolve outstanding discrepancies between reaction pathways and yield in isotope labeling experiments. This network also provides explanatory pathways for the high yield of hydroxymethylfurfural (HMF) and the reaction pathway that contributes most to the formation of hydroxyacetaldehyde (HAA) during glucose pyrolysis. Due to the limited domain knowledge required to generate this network, this approach should also be transferable to other complex reaction network prediction problems in biomass pyrolysis.