Viruses, generally the Plant based viruses are used as biotemplates for the synthesis of silver nanoparticles. This method is rarely used for the synthesis of AgNPs as compared to other chemical and green methods . Plant based viruses such as Cowpea Mosaic Virus, Red Clover Necrotic Mosaic Virus and Tobacco Mosaic Virus (TMV)are used to synthesis AgNPs [165]. Among, these viruses the TMV is the most studied and applied widely, considering the fact that very limited studies are carried out on virus-mediated green synthesis as compared to other methods. In a study, used TMV as biotemplate to synthesis the AgNPs of size 2-4 nm. The AgNPs obtained were coated on the inner surface of the cylindrical TMV channel. The synthesis process is mediated by amino acid . The AgNPs obtained by viral template is used in target imaging and to enhance the drug delivery system . Due to the rod shape of some plant viruses like TMV, the AgNPs obtained from plant-based virus biotemplate is used to synthesize 1D AgNPs . The 1D nanoparticles synthesized by using TMV biotemplate is advantageous as green reagents can act as both reducing and capping agents, which may significantly reduce the overall material cost . The synthesis is carried out at relatively low temperature or even at room temperature [168] which may reduce the energy consumption making it a feasible option for large scale production of 1D silver nanoparticles. Beside all these advantages the biotemplates often lack strong metal-binding sites [163] and the preparation of viral biotemplates is often time consuming . As the information on the synthesis of AgNPs through viral biotemplate is limited, further research is required to explore their full potential.