This reaction was not limited to pyridines, with -CF3 substituted pyrimidine also generating product 55 in a 55% yield. In addition to 6-membered nitrogen heterocycles, fused nitrogen heterocycles containing quinoline, boc-protected indole, imidazopyridine, and N-Me-benzotriazole moieties were tolerated by the reaction conditions (56-59), demonstrating the utility of this method for synthesis of complex bioactive targets. 1,4-dichloropyrazine reacted efficiently at the carbon-chlorine bond, to deliver product 60 in a 65% yield, without any overreaction being observed. Further products containing the benzothiopene (61) and phthalide (62) bicyclic structures were formed smoothly from their corresponding aryl bromides in high yields. To further show the synthetic applications of the new method, we synthesized in a single step the thiazole building block 63 (66%), which is commonly encountered as the C-Terminus of a number of peptides found in marine cyanobacteria, most notably biseokeaniamides A-C. Notably, synthesis of this compound required previously a 3-step procedure. Finally, we discovered that the protocol is not only effective towards arylation, but also vinylation, as shown by transformation of a β-bromo-styrene to product 64 under the same reaction conditions (68% isolated yield).