Water permeability through membranes was calculated from equation P = r/2c w , where r is the rate of permeation events per time and area, and c w = 33.3679 nm -3 is the concentration of water in bulk . The number of permeation events in each trajectory was calculated using the code by Camilo et al. , available at . The code that calculates permeabilities for all simulations in the NMRlipids Databank is available at /scripts/calcMD-PERMEATION.py, and the resulting permeabilities are stored at /Data/MD-PERMEATION in the repository containing all analyses specific for this publication at . This repository is organized similarly to the NMRlipids Databank repository, enabling the upcycling of also the analyzed data without overloading the main NMRlipids Databank repository.