• The Chinese Academy of Sciences, a group of 124 individual research institutions, 146 is a distinct leader with respect to the number of published patents in the field of CRISPR. A portion of their recent publications appear to be focused on: use of CRISPR/Cas13 systems for targeting and treating diseases, such as SOD1, We next took a look at patent activity data in the field of CRISPR therapeutics; an activity is defined as an event that leads to the publication of a patent document, for example application publications, issuing of patents, and among other events. An analysis of patent family activity data in Figure shows the flow from the patent assignee country (left) to the patent office where the first application in a given family is filed (center) and finally to the destination patent office for individual patent publications within the family. The United States leads in terms of sheer volume of patent publications, most of which are sent to the World Intellectual Patent Office (WIPO). Still, a decent sized portion of US patents go straight to the home office. For China, the second country/region leading in terms of sheer volume of patent publications, an overwhelming majority of patent applications appear to have been filed and granted at their home office. Most of the patents initially submitted to WIPO are subsequently submitted to US, the European patent Office, Canada, Japan, South Korea and China, with a smaller number being filed at patent offices in India, Brazil, Australia, and other smaller patent offices around the world.