For example, ropinirole, a drug used to treat Parkinson's disease, has showed potential in delaying the progression of ALS. The multifunctional brain permeable iron chelator M30 was shown to possess neuroprotective activities against various neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, and ALS. and carvedilol (CAS RN: 72956-09-3), medications used to manage gout and high blood pressure, respectively, were reported to significantly reduce the risk of developing ALS, Alzheimer's, or Parkinson's disease. MG frequently co-occurs with immunosuppressant and anti-rheumatic drugs (Figure ). Immunosuppressant medications act to lessen the immune system's response in order to avoid the immune attacks on NMJs, thereby limiting muscle fatigue. Common immunosuppressive medications used in treating MG include prednisone (CAS RN: 53-03-2), azathioprine (CAS RN: 446-86-6), cyclophosphamide (CAS RN: 50-18-0), methotrexate (CAS RN: 59-05-2), tacrolimus (CAS RN: 104987-11-3), and mycophenolate mofetil (CAS RN: 128794-94-5). Patients with rheumatoid arthritis exhibit high prevalence of MG compared to the general population. The rheumatoid arthritis drug abatacept has been reported to prevent MG in clinical trial. Another drug used in the treatment of rheumatoid arthritis, rituximab (CAS RN: 174722-31-7), has been also shown able to reduce the risk of deterioration in MG. Since there is no cure for these rare diseases, drug repurposing studies have been intensely searching to identify existing drugs that could be repositioned to be used as viable treatment options. As the pharmaceutical development process is both time-consuming and costly, drug repurposing provides a chance to accelerate it by exploring the beneficial effects of agents approved for other disorders. These drugs have established safety profiles, pharmacokinetic description, formulations, dosages, and manufacturing procedures. Recently, in silico pharmacology has been widely applied and various computer applications including machine learning and artificial intelligence approaches have been explored in identifying potential drugs for repurposing to various diseases.