The full technical details of PubChemLite are published elsewhere . Briefly, PubChemLite is derived from major categories relevant to environmental/exposomics applications appearing in the PubChem Table of Contents (TOC) pages of the PubChem database . The ten categories currently used to compile PubChemLite (see Figure Any compound with one or more of the selected annotation categories is included. The matching compounds (represented by PubChem Compound IDentifiers, CIDs) are aggregated by the first block of the InChIKey into a primary entry and related CIDs, where the primary entry is the neutral or "parent" form. Entries such as mixtures, disconnected substances, or those causing errors, such as some transition metals, are excluded (see the build system code for details ). Chemical information (SMILES, InChI, InChIKey, formula, mass), patent and literature (PubMed) counts plus predicted XlogP values are retrieved in bulk using PubChem APIs. The chemical identifiers, mass and XlogP values correspond to the "parent" (primary entry), while the annotation, patent and literature counts are aggregated across all related CIDs. Importantly, the presence of an entry in PubChemLite means that at least one of these annotation categories is available for each CID, with the resulting information publicly available on PubChem to help interpret the relevance of the candidate, see Figure . Since the chemical content of PubChem changes daily and annotation content weekly, PubChemLite is built and evaluated early Friday mornings, following the weekly PubChem update cycle. New versions are currently released publicly (typically last Friday of the month) on Zenodo (DOI: 10.5281/zenodo.5995885 redirects to the latest version).