Accordingly, the development of new methods that lead to straightforward, robust and modular preparations of secondary alkylamines remain a constant challenge to the synthetic organic chemistry community. While catalytic methods are emerging for their synthesis, most notably, alkene hydroamination, photoredoxmediated reactions, hydrogenation, biocatalytic transformations, C-H activation, and others, the majority of secondary alkylamines are still prepared by carbonyl reductive amination (CRA) or Nalkylation. A possible reason for this preference is that methods such as CRA offer an operationally straightforward, robust and widely explored means by which to prepare secondary alkylamines via the union of two classes of extensive and diverse building blocks, namely primary amines and aldehydes or ketones.