High conversions up to >98% were obtained with epoxides bearing saturated or unsaturated side chains and reaching up to 94:6 er. Experiments exhibiting high conversion combined with high enantioselectivity seem to be the case of epoxides which can cross easily the membrane. With our homemade reactor bearing 10 mL compartments, it was possible to obtain up to 4.3 g of each enantioenriched diol 2a. It is also noteworthy to mention that the membrane can be reused several times without loss of activity. A simple washing with hexanes, then with CH2Cl2, followed by a drying under vacuum makes the membrane able for a new compartmentalized transformation.