Analyzing our benchmark results (Figure ,D-G), we observe that the liquid bilayer properties show very good agreement with experimentally derived results obtained via SDP modeling. In the APL results (Figure ,D), we see a slight underestimation for PC, PG, and SM lipids by ~3 Å 2 . This is a compromise made to improve gel-liquid transition temperatures and phase separation properties, discussed in Sections 2.3.1 and 2.3.3. Note that a deviation from SDP results of ~3 Å 2 still represents very good agreement with experiments; state-of-the-art atomistic simulations with CHARMM36 and LJ-PME show average errors of approximately ~1.5 Å 2 over a significantly smaller benchmark set . We found both APL and phase separation properties to be strongly linked to the angle parameter of saturated tails (a_C_C_C). The APL of all lipids can be increased by ~2 Å 2 by lowering the force constant of the CG saturated angle parameter (a_C_C_C) from 14.5 kJ/mol/rad 2 to 12.5 kJ/mol/rad 2 , however, this also decreases gel-liquid transition temperatures, and phase separation properties in ternary mixtures are impacted negatively.