Catalysis by direct designed Nickel composite materials has grown exponentially for considerable applications including (reduction, oxidation, hydrogenation, hydrolysis, desulfurization,...) reactions in the past few decades. As nickel (Ni) has a strong affinity for cobalt, copper, and many other transition metals. Hence, present to it real sophisticated benefit in various technological fields. So, as issued here and in several other research papers, nickel-based catalysts especially composites (Ni0.9Fe0.1(HCO3)2, (NSAs), ...) have demonstrated as a good candidate for the oxygen evolution reaction (OER) and Ni-based near-surface-alloys (NSAs) are a powerful catalysts prospect with high selectivity and reactivity for efficient formic acid (HCOOH) production from CO2 respectively. Also, Ni(OH)2/Ni (1.1:1) catalyst has described as a good hydrogen oxidation reaction (HOR) catalyst which feature best catalytic performance as high as 6.8 time of that Ni/C catalyst. (Ni) composite materials as well revealed advanced properties for dry reforming of methane (DRM). Nickel-based catalysts such as (Ni/CNTs, Ni@h-BN, AuNi@SiO2, CuNi-MOFs, Ni-M@HAP,...) have shown great important for the hydrolysis of organic compound (ammonia borane (AB)) for green hydrogen (H2) synthesis. Possibly, these catalysts could be extended in diverse electrocatalytic and catalytic applications. Moreover, unlisted forms of Ni-based catalysts supported over a wide range of matrixes including zeolite materials, metal oxides (SiO2, Al2O3, CeO2, SiO2/Al2O3, TiO2, MnO2, Nb2O5, ...), carbons (doped with heteroatoms and undoped), polymer nanocomposites, and so fourth, revealed themselves as a potential candidate for hydrogenation of harmless (CO2) and harmful (CO), olefin, and as well as for sulfur removal from transportation fuels (gasoline). Therefore, (Ni and Ni-alloys) NPs anchored over these matrixes seems to be a perfect model catalyst for organic compounds removal through the catalytic adsorption process and conversion, and also might be extended to other catalysis applications.