The manner in which these tools interface with users determines their usability. Standalone desktop applications provide a user-friendly graphical interface for visualizing molecules, but they lack programmatic accessibility, meaning you cannot control them via scripts, and they cannot be integrated directly into other software as libraries. Jmol falls into this category. Web applications are interactive as well but typically render models on the client side, limiting them to JavaScript, which modern browsers support. Examples include 3Dmol.js and JSmol, the JavaScript version of Jmol. Resources such as the Protein Data Bank () and PubChem () rely on such tools to display three-dimensional structures.