The use of microelectrodes in both the reporting and detection cell allowed for currents close to the limit of quantification to be observed without significant capacitive current, as well as enabling the use of objectives with a higher numerical aperture. Measurement of the integrated fluorescent signal produced by passage of charge showed a linear relationship which was also dependent on the time-scale of the experiment. The processes in the reporting cell were also studied, and new insights on the use of glucose in countering photooxidation were proposed. There are still many improvements to be made to the reporting system shown here. Resolving the fluorescent signals observed at different time-scales is crucial to calculating the charge that has passed, and better time resolved signals could be achieved with alternative techniques like electrochemiluminescence. Potentiostatic control of nanoelectrodes and improvements to the sensitivity of photon detection will also help towards the conversion of charges below femtocoloumbs. However, the data shown herein suggests that using a fluorogenic reaction to report electrochemistry below the detection limit is possible and is a key step towards next-generation nanoelectrochemistry.