In general, the spontaneous curvature 𝑐 and the bending stiffness κ of surfactant monolayers are two important factors that determine the stability size of spherical nanobubble, just as for the stability of microemulsions. κ is strongly when mixtures of surfactants of different chain lengths are used, because of the resulting disorder of surfactant chains. Szleifer et al. found that for onecomponent surfactant membrane the curvature elastic constant can vary from 𝑘 𝑇 to tens of 𝑘 𝑇 by increasing chain length or by decreasing the area per molecule.