Compared to NMR spectra, UV/Vis spectra contain far less structural information, and this also holds for optical DOSY. However, there might be situations where the NMR spectra of species in a mixed solution overlap strongly, but the UV/Vis spectra are different: in this case, optical DOSY might be a useful addition to NMR-DOSY. Furthermore, the UV/Vis experiments do not require deuterated solvents, and can be done on paramagnetic compounds (which are not accessible to NMR), and the experiments can be done at comparatively low concentrations (see above). Furthermore, using nonlinear multi-dimensional spectroscopy it becomes possible to obtain more structural information from the UV/Vis spectra of molecules, and combining DOSY with such nonlinear optical spectroscopy should be comparatively easy to do.