The analysis of the trajectories obtained for all surface/solvent combinations reveals three broad groups of detachment mechanisms occurring, illustrated in Fig. . In a fraction of trajectories the process occurs via a linear path of detachment, represented by a simultaneous increase of the distance of the molecule from its lattice site, and loss of coordination with other solute molecules as shown in Fig. in green. This process can occur either with or without a significant change in the relative orientation of the molecule within its crystalline state.