The interplay between chemical transport and reaction kinetics is pivotal for understanding hormone dynamics within the endocrine system. Hormone action is a kinetic process dependent on their transport to receptor sites and subsequent binding. Disruptions in this coupling can alter the temporal and spatial dynamics of hormone signaling, contributing to endocrine disorders like metabolic syndrome and adrenal insufficiency . Therefore, in endocrine pathologies, such as diabetes mellitus, inefficient transport of insulin or its impaired kinetics can lead to elevated blood glucose levels and insulin resistance. Understanding this coupling is essential for developing targeted therapeutic interventions .