When selecting the most progressible fragments that are most readily accessible for further development, a higher %Exploited is a clear advantage. This higher percentage signifies that a greater number of exit vectors have been functionalized, indicating enhanced accessibility for synthesis. This additional perspective may be considered to support the decision-making process when identifying the best fragments to progress. To illustrate the potential of applying the EVPs statistics for selecting fragments in a screening library, a larger dataset of fragments was used to assess their progressibility based on the plot quadrant. Fragments with a high nEVPS have the potential to be considered progressible, since a certain number of vectors has been explored. However, for scaffolds sharing the same nEVPS value, a higher number of nEXIT and/or %Exploited may be more desirable in a fragment screening library.