In addition to modification of antibiotics, some multifunctional natural products with AIE properties have been applied for bacteria inactivation . Lately, Michelle et al. report an AIE active natural compound Tanshinone IIA and investigated its application in photodynamic eradication of biofilm (Fig. ) . Tanshinone IIA is a traditional Chinese medicine and it chemical structure is shown in Fig. . The photophysical properties were well characterized (Fig. ).