Paper, traditionally known for its use in writing and packaging, has evolved beyond its conventional applications. It has become a versatile material with properties that make it ideal for various applications, thanks to its physical characteristics. Paper is lightweight, flexible, and can be made thin, depending on the pulp processing. It is composed mainly of cellulose fibre, which can be functionalised to alter properties such as hydrophilicity, permeability, and reactivity. The development of paper-based microfluidics in recent years has made it an attractive platform for lab-on-a-chip devices capable of performing complicated laboratory tests on a large scale but on site.