Disinfectant use for cleaning both hands and surfaces has grown during the pandemic . Previous studies have shown pandemic related increases in concentrations of quaternary ammonium disinfectants in household dust , and higher risk of health effects due to increased exposure . Levels of two quaternary ammonium disinfectant chemicals increased in sludge during the overall study period (weekly samples, Figure , Table ). Triclocarban, an antibacterial compound used in consumer and medical grade handwashes increased in concentration in our daily sampling period (Figure ). Triclocarban was previously banned in medical grade hand washes (2017) and rubs and consumer hand washes (2016) for its endocrine disruption potential and other negative health effects . However, the most recent ruling against triclocarban (regarding consumer antiseptic rubs) took place in 2019, with an effective date of April 13, 2020 . Thus, it is likely that triclocarban products use had not yet been fully phased out during our study period. Additionally, the pandemic is likely to have prompted increased use of soaps and hand sanitizers that were previously stored. We identified an additional 3 disinfectant compounds for which there were no trends detected during the study period (Table ). ). All scatterplot error bars show the RSD for each compound, calculated from one set of replicate samples.