• Comparison of geographical distribution of patent assignees in the three diseases areas indicate a high degree of overlap, with countries such as the United States (USA), China (CHN), South Korea (KOR), Japan (JPN), Germany (DEU), Switzerland (CHE), the United Kingdom (GBR), and France (FRA) being common amongst the three. Denmark (DEN) shows up in the top 10 countries or regions for patent assignees in ALS and HD while Israel (ISR) features in the top 10 for ALS and MG (Figure ). Using our access to robust CAS indexing data, we further explored co-occurrences of the three rare diseases -ALS, HD, and MG, with a host of concepts such as other rare and non-rare diseases (Figure ), therapy types and drugs (Figure ), as well as proteins and cells (Figure ).