At the same time, readily available heteroarenes are prevalent in pharma-ceutically relevant molecules, thus, we turned our attention to the radical fluorosulfonamidation of heterocyclic compounds. By variation of the reaction conditions (see Supplementary Table ), we have first extended this radical fluorosulfonamidation protocol to indole derivatives. A series of indole derivatives with different functionalities including aldehyde, nitro, benzyl, tertbutoxycarbonyl (Boc), sulfonyl, etc., can smoothly give the corresponding fluorosulfonamidated products (5a-5u) in moderate to excellent yields (35%-89%).