The analysis revealed 3 % of weight coupling. . This shows that roughly 14% of the amine groups in MCM-N were bonded covalently through an amide linkage to the -COOH, highlighting a desired functionalization process as opposed to the previous study where the carboxylic acid group linked to the amine group was 56% percent , thus making it more protonated and hence undesirable for molecule sustained release at pH 5.