Having a fully characterized reaction network is insufficient to directly map the results to the experimental reactivity of materials. Inferring the reactivity from linear reaction profiles involving hundreds of intermediates and reactions is not straightforward since the CRNs in CARE (i) have undefined directionality at the global level as this depends on the definition of the initial reactants, (ii) are unconstrained to specific source and target species, and (iii) the catalytic activity depends on the applied operating conditions. Therefore, mean-field microkinetic modeling (MKM) functionalities for both thermal and electrochemical processes are included in CARE.