Furthermore, the substrate scope of N-acetylated primary amines with quinazolinone 1a were evaluated, and the results are list in Table . Functionalized N-ethyacetamides derivatives, such as aliphatic and aromatic amines-derived amides were employed to reacted with quinazolinone 1a under standard conditions. To our delight, aminoalkylation products with a simple alkyl group could be well-tolerated, and the corresponding products are obtained in good yield (3ab-3ag). To confirm the structure of the products, the crystal structure of 3af can be referred to figure S1 from supporting information. Interestingly, cyclobutyl and cyclohexyl methyl group also proceeded smoothly (3ah-3ai, 56%-69%). Besides, acetylamine bearing a benzyl or pyridine group performed generally well in this reaction, and the corresponding products (3ai-3am) were obtained with medium yields (50-76%).