Another example of poor sampling was identified where energetically similar minimum energy clusters had poor overlap between their mirrored minimum energy structures. Here both left-and right-handed clusters were identified, however due to poor overlap between the mirrored minimum energy structures of each cluster, these clusters were not labeled as mirror clusters, resulting in extremely small energy gap Z-score where larger values would have been reported. The θ B = 124 • model (figure ) exhibited this inadequate sampling.