The mediation mechanism, however, is not immediately obvious as direct C2O4 2-oxidation occurs at a potential that is ~0.4 V less positive than DiMeFc oxidation and is unaffected by the presence of DiMeFc. Mediated oxidation of C2O4 2-occurs upon oxidation of DiMeFc, which also overlaps with the oxidation of C2O4 2-•CO2. Thermodynamically, both C2O4 2-and C2O4 2-•CO2 can be oxidized by DiMeFc + via eqs 13 and 14, respectively. Note that eq 14 is equivalent to the sum of