Within the working_examples directory of the SEEKR_tutorials repository, there exist three subdirectories, i.e., beta_cyclodextrin_guest_complexes, trypsin_benzamidine_complex, and simulation_data (Outline 1). The beta_cyclodext-rin_guest_complexes and the trypsin_benzamidine_complex directories contain all the necessary files for running SEEKR2 simulations for receptor-ligand complexes. The simulation_data directory contains reference SEEKR2 simulations offering users to perform post-simulation analyses. To start with the tutorials, we now navigate to the working_examples directory: