The relationship between the type of carbohydrate and/or the nature of the linker and the antiparasitic activity for the reported dyads follows no obvious trends, and prediction of efficacy related to the various chemical modifications is not straightforward. Some differences in anti-toxoplasma efficacy are observed when the conjugates are applied at 0.1 µM. For instance, glucose ester derivative 19 is significantly more active on T. gondii compared to the amide analogue 20. Galactose functionalized compound 22 is more efficient in inhibiting the parasite proliferation compared to the corresponding glucose derivative 21, while for the same carbohydrate an increase of the linker length has a negative effect on the antiparasitic activity (galactose conjugates 22 and 23).