On contrary, the optical detection methods by using small organic molecules as colorimetric and fluorescent probes offer remarkable sensitivity and selectivity, fast, easy-to-operate, in-situ analysis, noninvasive for biological imaging applications and so on. However, the characteristic paramagnetism of Cu 2+ leads to the strong fluorescence quenching of the fluorophores after complexation owing to the enhanced intersystem crossing (ISC) of fluorophore´s electrons from excited singlet state (S1) to the triplet state (T1) by subsiding radiative transitions from S1 to ground state (S0), thus it usually makes difficult to design fluorescent turn-on probes. Therefore, its paramount to develop fluorescence turnon sensors for the detection of Cu 2+ ions and some of their reports are available in the literature primarily employing only one type of the different detection mechanisms due to which still some challenges persist regarding to low sensitivity, poor or no colorimetric visual detection and complex design strategies.