To achieve highly sensitive detection, particularly in the detection of very dilute concentrations, in the parts per million (ppm) or parts per billion (ppb) ranges, our enzyme-based Nano biosensor has the potential to be coupled with electronic devices such as Amperometers, Galvanometers, or Potentiometers. This synergistic approach could enhance the biosensor's precision and widen its applications, making it an invaluable tool in environmental monitoring and food safety assessments.