After the diffraction patterns are successfully indexed and integrated, they are merged to obtain a complete dataset, which can be further used for downstream map generation and structure refinement. The patterns were merged and analysed with the program partialator and compare hkl (see Section 3 of the SI for more details) of the CrystFEL suite . Higher indexing rates should lead to improved merging statistics. Therefore, the data quality indicators CC 1/2 and I/σ in combination with the redundancy of the reflections were used to assess the performance of TORO in comparison to XGandalf and MOSFLM. As proposed in , the indexing step in indexamajig was done with the default checks disabled (flags --no-retry --no-refine --no-check-cell) in order to ensure a fair comparison between the indexers. Results for the four proteins are reported in Figure . Results with the default checks enabled can be found in Figure of the SI. On average, TORO performs similarly to XGandalf, and outperforms MOSFLM for all four cases, as expected from earlier studies with XGandalf and MOSFLM :