Next-generation sequencing (NGS) is a genomic testing technology that is used in ART to screen embryos for genetic defects. Preimplantation genetic testing (PGT) using NGS helps identify genetic abnormalities in embryos. It can identify euploidy, aneuploidy, and chromosomal mosaicism. Using PGT enhances the likelihood of healthy pregnancies while minimizing the risk of genetic disorders. Cryopreservation enhancements: Cryopreservation techniques in ART have improved in several ways, including vitrification -a rapid freezing process that prevents ice crystal formation, improving survival rates of frozen gametes and embryos, coupled with improved and optimized cryoprotectants, vapor tanks storing tissue in the vapor phase of nitrogen instead of immersing it in liquid nitrogen, offering better survival rates for frozen eggs, sperm, and embryos, increasing ART success rates. Fertility preservation innovations: Techniques such as ovarian tissue cryopreservation and artificial ovary development are advancing, benefiting individuals facing fertilityimpacting medical treatments. Ovarian rejuvenation technique is used to stimulate the ovaries to produce new eggs, particularly in women with diminished ovarian reserve or premature ovarian failure. It may include injecting platelet-rich plasma (PRP) into the ovaries to stimulate tissue repair and egg production, or stem cells to regenerate ovarian tissue. The technique is still experimental, with mixed results in early studies.