In this comprehensive study, a novel approach for the industrial separation of gas mixtures through gas hydrate formation was extensively investigated, specifically targeting the capture of CO 2 from emissions released in combustion plants. Unlike other hydrate-based processes that operate with liquid water, this innovative method leverages the advantageous thermodynamics of hydrate formation at sub-zero temperatures, where CO 2 capture and regeneration prove particularly energy-efficient due to the neutral energy balance in the breaking and forming of hydrogen bonds during ice-hydrate transitions. Main drawbacks generally associated with the low temperature and the solid state of the ice, e.g., difficulties in handling the solid, poor formation kinetics, cycling performance, and a reduced uptake capacity, have been anticipated but could be successfully addressed using a fixed bed reactor with silica-stabilized ice. The bed offered exceptionally high surface area which could not only be maintained but, in some instances, even enhanced during repeated low-temperature formation-dissociation cycles-presumably due to pore formation processes upon cyclic solid-solid transitions . To confirm the theoretical advantages and demonstrate the successful navigation of anticipated challenges, the process underwent thorough testing across various operational modes, focusing on thermodynamic equilibria, formation kinetics, and practical, continuous capture-regeneration cycles in an industrial setting.