The total ISC rate for THP is 100 times smaller than the fluorescence rate when considering only the implicit solvent. However, it is about the same as the fluorescence rate when considering the explicit solvent. Thus, ISC may compete with fluorescence in THP. Assuming that the probability of fluorescence and ISC is exponentially distributed, the odds that ISC occurs before fluorescence is kF/(kF + kISC). Thus, if no other reaction path is available, ISC should occur for 40% of the excited THP.