In this regard, the development of nanoscale materials with biological activity in a broader spectrum for broader applications as antimicrobial agents is of interest . Among the semiconductor materials, ZnS and ZnO are very promising owing to their outstanding physical properties, manufacturing simplicity for different synthesis strategies, low cost, high chemical and thermal stabilities, and high versatility for several technologies (such as, ultraviolet light diodes, photocatalysis, sensors, and solar cells) . They also exhibit high antimicrobial activities .The hydro(solvo)thermal method can be used as a low-cost approach to produce ZnS and ZnO nanoparticles (NPs) with high purity and crystallinity . Further, the morphologies of ZnO and ZnS crystals and their physical properties may be tuned by their shapes and sizes, which are optimised by the synthesis parameters, such as the supersaturation, temperature, solvent and precursors, which affects the hydro(solvo)thermal growth kinetics of NPs . Based on the broad-spectrum antimicrobial activities of ZnO and ZnS NPs, they have been extensively investigated compared to other advanced materials as nontoxic to human cells . In addition, ZnS and ZnO are classified as safe materials by the Food and Drug Administration agency .