As known many molecules coexist in the living being blood, and urine. Those molecules play a crucial role in the biological systems. As an example, in human being, generally there coexist Ascorbic Acid (AA) and Dopamine (DA) in the extracellular liquid. Moreover, in the human's blood and urine it coexists Uric Acid (UA) and (AA). So, it is known that these kinds of compounds are of great interest in biomedical systems which play a key factor the human metabolism, central nervous, renal systems, and beyond. However, abnormal levels of these molecules can lead to a drop-off in the biological system function. For abnormal level of (DA) can lead to several neurological disorders, for i.e. Parkinsonism, Schizophrenia. Also, high levels of (UA) can cause the gout and hyperuricemia. But its low level are related to the disease as Scurvy. In the case of glucose, superior levels can yields to the disease named as diabetes, which cause nowadays much loss in human life. Although, there are many materials (electrodes) available in the mark for the detection of biomolecules in the real samples. But, there is a higher need in the development of a new and powerful platform for the early and facile sensing of these biomolecules with cost-effective, high selectivity, as well as best sensitivity, superior stability.