We then used the transition metal element Co in the catalytic reaction and used Co-based catalysts synthesized from different carrier materials as a control group to verify the catalytic effect. As shown in the graphic results, the product selectivity of nitrile hydrogenation is not only related to the properties of the metal species but also inseparable from the carrier. When using microcrystalline cellulose as a raw material, the non-nitrogen-doped catalyst Co@MC only gave a conversion rate of 74.14% and a selectivity of 89.90%, which is in contrast to the almost complete yield of the catalyst wrapped with the nitrogen-doped carrier chitosan, indicating that N-doping of the carbon carrier can significantly improve the catalytic activity. At the same time, we also used the empty carrier CS in the reaction for comparative experiments. It can be seen that almost no hydrogenation reaction occurs under the pure carrier catalyst, indicating that Co is an active substance that can carry out this reaction. Subsequently, we moved the reaction to a continuous flow micro-packed bed reactor to further optimize the reaction conditions.