Docking score distributions from large sets of independent runs provide much information about the bound ligands . Breaking the distribution into a set of peaks shows the conformational The score distributions for each of the 6 combinations are shown in Figure . In each of the 6 combinations it is clear that there are 2 major conformations coming from 2 separated and large peaks. The P197 and S197 AHAS structures are different, even if only one amino acid is changed.