The effective magnetic field that is sensed by nuclear magnetic moments, although mainly dictated by the external field, is slightly affected also by the field generated by electrons. Therefore, in high-resolution spectrometers, with a high homogeneity of the external field, all nuclei experiencing a different chemical environment sense a slightly different magnetic field with respect to one another. This results in a different chemical shift of the nuclei with different chemical environment, i.e. in a resolved NMR spectrum. The relaxation rates of individual nuclei present in a macromolecule can thus be measured, as well as the rate of bulk solvent nuclei. In order to obtain the field dependence of these relaxation rates, measurements can be performed by shuttling the sample between different positions inside the NMR spectrometer, in such a way to cycle between different magnetic fields. Shuttling the sample back and forth in the stray field of a high-field spectrometer thus permits to polarize and detect the signals at the high-field position while letting polarizations relax at low field. Measurements performed in the high field position can thus report on the relaxation rates of individual nuclei at lower fields, so that high-resolution relaxometry can be performed.