) (Figure , B), which hints towards a A-pBuOzi-A/D 2 O mixture with a slightly higher D 2 O-fraction. The second, very small, shell contains almost only D 2 O as judged by the SLD (Figure ). Being very small and essentially D 2 O, this second shell is negligible. With increasing CUR concentration, the SLDs of the core and both shells decrease indicating further dehydration. After reaching a CUR concentration of 3 g/L, the SLDs of the system remain almost constant. This indicates a possibly stable composition in every part of the micelle. According to the SLDs, it appears as though CUR is mostly present in the core. At the highest possible CUR concentration of 10 g/L, the morphological situation is somewhat similar to the situation without CUR, as the composition of all components appears to be quite similar, according to the SLDs (Figure ). Accordingly, we cannot consider the micelles anymore as core-shell-shell structure but rather a large homogenous sphere. A similar distribution of CUR into the outer, hydrophilic shell of glycopolymers was previously observed by Stenzel and coworkers using SANS. Increasing amount of CUR dehydrated the nanoparticle shell, which coincided well with a lower cellular uptake of the respective nanoparticles.