Controlling the structural physical and chemical properties of the interface can be readily achieved by modifying the metallic surface with organic molecules among which thiol monolayers are of special importance with a wide range of applications extending from biosensing , catalysis , to interfacial charge transport . Such monolayers allowed for pivotal advancements in drug delivery , protein adsorption onto surfaces , as well as basic research of surfaces and interfaces , and solar cells . Despite immense efforts to understand the physics behind the self-assembly of such monolayers, both theoretically and experimentally (including the energetic and kinetic aspects of adsorption , exchange and desorption , locations of the exchange and its mechanism ), various aspects of the monolayer dynamics remain obscure. In the context of the potential applications for such monolayers, their stability and dynamics, including the exchange of the surface molecules, are of utmost importance. This naturally extends to establishing appropriate tools to monitor such transformations.