The BLASTp search against the non-redundant database of the human proteome, setting an e-value threshold of 0.0001, revealed 20 non-homologous EHPs out of 24 functionally annotated EHPs. For an ideal drug target, it should not have any close homologs in the human proteome so that it can minimize the unwanted cross reactivity of a potential drug with the host proteins . Therefore, these non-homologous proteins are pathogen specific, which means solely present in the pathogen, and can be further studied to find an ideal drug target. Sheikh Sunzid Ahmed