We hope that, through freely available sourcecode and example workflow configurations, we have lowered the barrier to entry, and increased the usability of non-equilibrium binding free energy calculations in drug-discovery applications. Furthermore, as the computational cost of free energy calculations continues to fall with ongoing advances in software and hardware, we believe that automated workflows that retain a high degree of control for the expert user will become increasingly important, as these predictions become part of large computations, for example active learning and de-novo design tasks.