Dietary supplementation is an anti-aging strategy that targets a wide range of indications. The University of Sherbrooke, Canada researched the use of medium chain triglycerides (MCT) combined with aerobic (AE) exercise on ketone production in a group of 20 women (prediabetic and healthy) over the age of 60 years through clinical trial NCT02678390. They discovered that MCT (30 g/day for 5 days) combined with AE (30 mins) was more ketogenic in older women than MCT or AE alone. A clinical trial (NCT02446314) researching the use of two different blueberry formulations for the treatment of cognitive decline in 125 participants 65-80 years old. Treatment groups consisted of a 6-month daily regime of 450-900 mg of blueberry powder or 100 mg of blueberry extract. The results reveal that the blueberry extract intervention can improve episodic memory and cardiovascular biomarkers over 6 months. The same effects were not observed for the blueberry powder intervention or with the measurements of executive function, working memory, or mood. Several current studies are exploring the use of collagen for age-related indications. NovoBliss Research, India is researching the effect of vegetable, bovine, fish, and chicken collagen peptide for indications such as skin elasticity, wrinkles, and hydration, hair thickness and density, along with joint pain and osteoarthritis. 125 participants are currently enrolled with treatment groups of 0.5 -10 g/day. 699 Shenzhen Precision Health Food, China also has a registered trial (NCT05682092) researching the use of collagen peptide to increase skin moisture and elasticity. The trial is not yet recruiting but plans to enroll 70 middle aged (30-50 yrs old) women who will consume 25ml twice a day for two months if in the treatment group. Lastly, we discuss Medical College of Wisconsin's clinical trial NCT05598359 that is not yet recruiting but will be researching the use of TA-65, a purified small molecule extracted from Astragalus root. 180 participants will be recruited to investigate the use of TA-64 (250 U) taken once per day on microvascular function and blood pressure. 700