Here, we demonstrate the application of the high-throughput method in the phase analysis of a polycrystalline product resulting from the melt crystallisation of a griseofulvin (GSF) and polyethylene (PEG) mixture. GSF is an orally-administered antifungal drug and has five polymorphic forms (Table ) . Since the drug is poorly water-soluble, GSF has been formulated as an inclusion complex (IC) with PEG (GSF-PEG IC) to improve the dissolution behaviour . During previous studies on the melt crystallisation of GSF from dispersions with PEG , we discovered a spherulite nucleating at 80 °C in 90% GSF-10% PEG 1000. The spherulite had a unique melting behaviour (transforming completely to GSF Form V once heated above 120 °C) and showed a small shift in the Raman spectrum at 1660 cm -1 (Figures and). These properties indicated the discovery of a new crystal form.