To the best of our knowledge, only one article can be found in the literature regarding the electrochemical reduction of an aminoquinoline derivative in an aqueous solution on glassy carbon electrodes. For hydroxychloroquine a single, pH-dependent cathodic peak was observed (below potential -1.2 V vs. SCE). The authors suggested an EC mechanism where one electron is consumed. Reduction of AQ in organic solvents is strongly dependent on solvent properties. In aprotic media two reversible electron transfer processes leading to the anion and dianion radicals were observed. In protic media a single two-electron step leads to the generation of dihydroquinolines.