As can be seen in Figure , the CE-cells expressed much higher levels of calnexin compared to the CE-EVs. The low levels of calnexin in the CE-EV sample could indicate low levels of residual cell debris. Furthermore, collagen type I and fibronectin were investigated since ECM proteins are considered to be important for corneal wound healing. Collagen type I was not very abundant in neither CE-cells nor CE-EVs and the levels seemed to be similar in both, suggesting that collagen is not accumulated in the CE-EVs. However, fibronectin was significantly more abundant in the CE-EVs compared to the CE-cells suggesting its importance. This is in agreement with the literature which suggests that fibronectin and other provisional ECM proteins are important in the first stages of wound healing in the cornea and that collagen type I is formed at a later stage of wound healing.