For all experiments crosslinked with amines, reactions were conducted in a solvent system of 1:1 BuOH:DMF. Alcohols are known to catalyze the reaction between amines and epoxides through the formation of a trimolecular complex . Thiol-crosslinked reactions were conducted in MeCN with 10 µL of 2 M LiOH as a catalyst, necessary to deprotonate the thiols in order to perform a nucleophilic attack on the epoxide ring .