First, we searched for the simplest way to make iodo-BCPs. We aimed to directly convert commercially-available BCP-1carboxylic acids to the corresponding iodides as an alternative to strain-release reactions of [1.1.1]propellane or decarboxylation of redox-active esters. Chemists at Enamine solved the longstanding challenge of preparing BCP-1,3-dicarboxylic acid on scale , leading to increased commercial availability of 1a, an intermediate that costs $6.8/mmol. The iodo-BCP 2a costs $383/mmol (Scheme 2C). 19 2a has previously been prepared via stepwise Barton ester formation and decarboxylation or via the Kochi reaction , which employs a toxic lead salt. Gandelman reported a mild modification of the photo-Hunsdiecker reaction using diiodohydantoin (DIH) as an iodinating reagent. It was unknown whether these conditions could be extended to BCPs, which were not included in the original substrate scope.