In 2018, the Global Perfluorinated Chemicals Group 27 within the OECD published a list of 4,730 PFASs to develop regulatory approaches for reducing the use of perfluorinated substances in products. However, researchers have yet to discover the bioactivities of the molecules in the list. Using the QSAR model developed in this work, we give predictions and a rationale for the bioactivities of molecules in the OECD list.