To sum up, we present a family of compounds with NO-releasing ability and singlet oxygen formation. The maximal NO yield and the release speed was observed for BODIPY-NOD-2, whereas maximal 1 O2 generation was detected for BODIPY-NOD-3. Observed low efficiency of NO photorelease in the case of significant 1 O2 generation could be also explained by the reaction with oxygen with the formation of peroxynitrite . This process is an alternative to the reaction with DAR-2 probe, which reduces its apparent fluorescence. Still, these experimental results show that the introduction of heavy atoms into the BODIPY core does not enhance the photorelease of NO, indicating that the latter proceeds from the singlet state.