Returning to the material TlF3 (Figure ), its ease of exfoliation is perhaps surprising as at first glance there is no obvious layered sub-structure (only upon closer inspection are the elongated bonds noticeable: 2.42 vs 2.15 angstroms). This observation suggests that significant lattice gaps in the atomic structure are not necessary for a material to have a small exfoliation energy. Even if a bulk material does not exhibit layered structure, it may have the potential to be stripped down into a two-dimensional layer. In fact, non-van der Waals layered materials have been successfully exfoliated recently in experiment. Ilmenene, for example, has been exfoliated from the naturally occurring titanite ore ilmenite (FeTiO3) by employing liquid phase exfoliation in a dimethylformamide solvent by ultrasonic bath sonication. Similarly, a new two-dimensional material 'hematene' has been successfully obtained from the natural iron ore hematite (α-Fe2O3), by means of liquid exfoliation. Finally, In the work of Ma et al. they report successful exfoliate of stable monolayer wurtzite semi-conductors from bulk materials that are non-vdW material and show isotropic in three crystallographic directions. This is a fascinating and surprising new avenue of research in the field of 2D materials, and it is hoped that the tools and data presented in this work can be brought to bear in understanding this new phenomenon in future work.