These steps are likely to resemble the life-cycle steps of conventional paracetamol manufacture; for LCAs on tabletting and packaging of conventional paracetamol products the reader is referred elsewhere. The LCA model was built using GaBi ts software (v10.0.1.92) with the ReCiPe 2016 v1.1 midpoint-level (H) impact assessment methodology. A description of the developed GaBi model is given in SI Section S7.1. Core LCI data for this study was extracted from a model of the manufacturing process constructed in Aspen using bench-scale experimental data. An LCI for CST production from Kraft pulping was adopted from the literature. 17 LCI data for ozone production was adopted from online manufacturer data as outlined in SI Section S3.2.