1. Lipid -Based nanoparticles like liposomes Nanostructured Lipid Carriers (NLCs) and Solid Lipid Nanoparticles, this enhances Curcumin stability and bioavailability . 2. Dendrimers: These are Curcumin branched particles that enhance solubility and targeted delivery . 3. Polymeric Nanoparticles: In this the Curcumin is encapsulated by polymers like PLGA, thus ensuring sustained release and biocompatibility . 4. Micelles and Nano emulsions: These are the surfactant-based systems that improves solubility, therefore enhancing tumor penetration . 5. Gold and Magnetic Nanoparticles: These facilitate image guided cancer therapy and enhance photothermal or photodynamic effects .