Nanohydroxyapatite is a well-known bioceramic with exceptional properties and applications in the biomedical field. Their textural, morphological, and biological features present a tremendous potential drug carrier for antimalarial drugs . It is osteoconductive, osteoinductive, biocompatible, has a synergistic therapeutic response with some medications, is significantly effective, non-toxic, crystalline, has extended-release (dependent on the synthesis process and starting material), and has a modifiable morphology . Furthermore, nanohydroxyapatite is easily synthesized using plant extracts as templates . The advantage of synthesizing nanohydroxyapatite using plant extracts is that it substitutes synthetic templates and allows the surface functionalization of nanoparticles with plant metabolites .