Clearly, the rules uncovered by SGD provide physical insights by identifying the key parameters favoring the effective CO 2 activation on SAAs. Nonetheless, each of the constraints identified by SGD does not necessarily have a specific physical meaning, as only the combination of all constraints describes CO 2 activation. In addition to the physical insights, the SG rules provide an efficient way to search for new SAAs containing different metals. This is because the parameters entering the rules in Expression 5 can be evaluated for a large number of surface sites in alloys. In particular, it is desirable to identify SAAs that can activate CO 2 and contain more earth-abundant elements than those in the identified SG (Os and Ir). In the following section, we perform the screening of SAAs considering a broader number of candidate elements.