From previous chemical analyses of the pyroplastics, the relative abundances of BaA, C0, BbF, BaP, and IND were comparable, and BkF was much less abundant than the others. 9 Thus, the FACTORIAL profiles of the pyroplastics are unlikely to reflect the additive sum of the profiles for the individual compounds within the extracts. At first glance, this outcome aligns with evidence showing that complex mixtures of PAHs behave differently than single PAHs from a toxicological standpoint. Yet, in contradiction to this, the pyroplastic extracts primarily reflected profiles of a single PAH, but for a profile of a single PAH at a ~10-fold greater concentration than is estimated to have been in the extract. Future work should investigate the FACTORIAL profiles of PAH mixtures to better interpret the contributions of each chemical component to the overall toxic potential of PAH complex mixtures that more represent real-world samples.