Radical rearrangement is a powerful tool for the construction of complex aromatic structural motifs with otherwise hard-to-construct connectivity. In this context, migration strategies of C-centered, π-system-containing functional groups (FGs), such as aryl, heteroaryl, cyano, alkenyl, alkynyl, and ester, have been intensively studied by organic chemists in the past decades (Scheme 1a). In contrast, although nitrogen plays vital roles as a bio-element in organic and bioorganic chemistry, the radical migration of N-centered FGs has rarely been explored. Radical 1,n-nitrogen migration occurs naturally in the lysine 1,2-aminomutase-catalyzed interconversion of L-α-lysine into L-β-lysine in Clostridia. In this regard, a chemical 1,2-imino-migration model for the pyridoxal 5'-phosphate dependent Lysine aminomutases was established by Frey et al., where an ipso-addition onto an imino π-bond was followed by β-fragmentation, finally enabling the 1,2-N radical shift (Scheme 1b). Recently, such an imino-migration has also been extended to a distalshift version (e.g., 1,4/5-imino shift) by Besides, Cu-catalyzed oxidative radical 1,3-migration reactions of α,α-disubstituted benzylamine via 4-exo-trig cyclization of an aminyl radical to phenyl ring were recently developed by Wang and others (Scheme 1c). Additionally, through an insertion of metal nitrene into C-H bond, an elegant example on radical 1,3-nitrogen migration accessing to chiral αamino acids were reported very recently by Meggers and co-workers. However, despite the afore-mentioned advances, these radical 1,n-N-migration reactions has been mainly limited to π-system-based versions (e.g., imino, azido, phenyl, and etc.), 4-6 and π-system-independent N-shift strategies remain rare and in high demand by synthetic practitioners.