Silyl modification could also be used to introduce handles for attachment of dyes to sensors or biomolecules. A commercially available dichlorosilane includes a norbornene group, which could potentially be used for Inverse-Electron Demand Diels-Alder (IEDDA) click chemistry with tetrazines. We synthesized norbornylsilyl dye 16 as a mixture of four isomers (exo/endo norbornene and two atropisomers), and found that the norbornene dye isomers react with methyl tetrazine NHS ester under mild conditions (Scheme S1). Although the NMR was difficult to interpret due to the presence of multiple isomers, HRMS indicated that the expected cycloaddition products are formed, consistent with the oxidized aromatic pyridazine product rather than the dihydropyridazine (Scheme S1).