For the remainder of this work, we make a distinction between two different methods for the calculation of ∆H diss,T . Since the temperature dependence of ∆H solv,T can currently only be calculated for some common solvents, our first method neglects the temperature dependence of the dissolution enthalpy. In the second method, the temperature dependence is accounted for through numerical integration. Other properties (∆H sub,298K , C p,g , and C p,s ) can be calculated using recently published correlations by Abraham and Acree 29,30 combined with machine learning predictions of solute parameters.