To understand the interaction between the LP-NCs and water/CO2 the heat of adsorption ΔadsH was determined using the Van 't Hoff equation. All fitting parameters are provided in Figure -S19 and Table -S2). The optimized sensor shows very large ΔadsH values of -35.6 kJ•mol - 1 and 34.1 kJ•mol -1 for H2O and CO2, respectively. Similar values for ΔadsH for CO2 adsorption in porous N-doped carbons are reported. The ΔadsH values for the reference LPO2-Ade380 only exhibit 21.3 and -81.7 kJ•mol -1 for CO2 and H2O, respectively. This is attributed to the foaming effect in LPO2-Ade38090/Glu30010, resulting in a higher amount of exposed pyrrolic/imidazolic N.