To further explore this idea, let us task the deep dreaming model with maximising the VF of a MOF. We can do this by assigning a target VF which, in this experiment, we will set unphysically high at 1. Starting from a seed MOF structure, the model will make minor adjustments to the edge SBU encoding over hundreds of training epochs corresponding to the deep dreaming process. Every adjustment has the potential to produce a pronounced transmutation of the linker molecule. However, when the model traverses regions of the chemical space that decodes to an invalid linker molecule, an additional loss term is added to the target loss in order to guide the optimisation down valid chemical pathways (c.f. the Optimisation of MOF linkers section). For example, in Figure , we define the valid transmutation pathway as the series of successful linker modifications, while the transmutation pathway simply refers to all the modifications suggested by the model, valid or not. By inspection of the valid transmutation pathway, we can clearly see an extension between connection points of the linker from the initial seed to the final decoded structure, as anticipated.