The synthesis of the DCAF11-recruiting PROTACs was completely carried out on solid support and is shown in Scheme 1. For resin modification, loading determination, and amide coupling reactions, our previously published protocols were used. Specifically, the commercially available 2-chlorotrityl chloride (2-CTC) resin was modified with N-hydroxyphthalimide to immobilize the hydroxylamine as the precursor for the hydroxamic acid on the resin (not shown).