With the establishment of a chromosome-level high-quality reference genome map of Taxus in 2021, the biosynthesis of anti-cancer drug Paclitaxel shown in Figure has become a more active area of research due to the potential to increase drug compound yield using economical and convenient cultures. Therefore, 10 2024 abstracts were summarized by the manuscript's author in the following paragraphs for comparison purposes to AI regarding the taxane drug's biosynthesis. 18 O labelling and density functional theory calculations, a possible reaction mechanism was proposed involving intramolecular oxidationacetoxyl rearrangement through a concerted process published in .