Fig. exemplarily shows three lysosomotropic reference compounds -Imatinib, Toremifene, and Clozapineand their CP profiles in comparison to SAG. The morphological profiles of these three compounds and that of SAG are very similar, although these compounds have di↵erent primary targets and chemical structures. Imatinib, a tyrosine kinase inhibitor, is primarily used to treat chronic myeloid leukemia, 40 whereas Toremifene, a selective non-steroidal estrogen receptor modulator, is administered to treat breast cancer. Clozapine is an anti-psychotic drug used in the treatment of severely ill patients with schizophrenia. While Clozapine's mode of action is unknown, it is proposed to be an antagonist of dopamine and serotonin receptors.