In summary, we have developed an inventive example of domino annulation reaction of crotonate-derived sulfur ylides and dienes to generate highly functional none-fused sevenmembered cycles such as nitrogen-heterocycles and carbocycles with moderate to excellent yields. The advantages of the current reaction include available and easy-synthesized materials, mild reaction conditions, good functional groups tolerance, and extensive substrate scope. In addition, this is also a supplementary to sulfur ylide chemistry as the C3 synthesizer, and we are confident that this type of reaction has important application potential in the synthesis of natural products and bioactive molecules.