To implement UVPD fragmentation on the ZenoTOF 7600 system, the EAD cell was modified, and one of the two EAD filaments was replaced by a mirror to redirect the UV photon beam in the center of the EAD cell, as shown in Figure . One high transmission UV-Visible grade calcium fluoride CaF2 windows were mounted on the vacuum chamber cover to get the photons from the laser inside the vacuum chamber. The software was adapted to add UVPD acquisition functionalities in addition to CID and EAD using DDA, DIA, and MRM HR acquisition modes.