Mass spectrometry experiments were performed on a SELECT SERIES Cyclic IMS QToF (Waters Corp., UK) fitted with a post-mobility ECD modification (e-MSion, US). The instrument was operated in sensitivity mode, and calibrated using sodium iodide (NaI) to within 1 ppm over the m/z range 0-8000. Samples were infused into the instrument using nano electrospray (nESI) capillaries prepared in house using a Flaming-Brown P97 micropipette puller, and gold-coated with a Quorum Q150RS sputter coater. Parameters used for analyses were: Capillary Voltage 1.4 kV; Sampling Cone 40 V; Trap Collision Energy 8 V; Transfer Collision Energy 6 V.