Phenoxy ring-substituted phenylcyanoacrylates served as multipurpose screening compounds , as products of microwave-assisted Knoevenagel condensation of ethyl cyanoacetate with aromatic aldehydes in aqueous triazine-based microporous network , in simple, efficient, and green method for synthesis of trisubstituted electrophilic alkenes using Lipase as a Biocatalyst , imidazolium chloride immobilized SBA-15 as a heterogenized organocatalyst for solvent free Knoevenagel condensation using microwave . Preparation of ethyl 3-(4-benzyloxyphenyl)-2-cyanoacrylate was reported . This cyanoacrylate was also described in synthesis, biological evaluation, and molecular modeling studies of arylidene-thiazolidinediones with potential hypoglycemic and hypolipidemic activities as well as in its synthesis as analytically pure compounds in flow reactors . The use of electroosmotic flow as a pumping mechanism for semipreparative scale continuous flow synthesis of this acrylate is reported in . Parabenzyloxyphenyl-2-cyanoacrylate is mentioned in synthesis and biological activity studies of novel acridinylidene and benzylidene thiazolidinediones . It is also reported in the preparation and reaction of enolates within micro reactors . Solid-supported continuous flow synthesis of this cyanoacrylate in microreactors using electroosmotic flow (EOF) was described . Nucleophilic Michael addition of 2-thioxo-4-imidazolidinone to 3-aryl-2-cyanoacrylates followed by benzylation gave 5-arylidene-3-(4-bromobenzyl)-1methyl-2-thioxo-4-imidazolidinones. All products were obtained as Z isomers . This cyanoacrylate was involved in preparation of (alkoxybenzyl)pyrrolidinone derivatives as nootropics .