between 48 and 125 nm, and low particle size distributions (PSD) in the range of 0.02-0.14, as shown by DLS (Table ). However, increasing f PtxMA,0 to 0.1 (PT5) yielded very small nanoparticles (D z = 17 nm) and broad PSD (Figure ), which could be explained by the high solubility of PtxMA in DMF, preventing efficient copolymer self-assembly. Another reason could be a potential crystallinity driven self-assembly which would be disrupted by the high PtxMA content. Also, when switching from BMDO to MPDL (PT6) for a fixed PtxMA content (f PtxMA,0 = 0.067), bigger particles with broader PSD were obtained.