Because each DIPA has only one nitrogen atom, once such DIPA-water dumbbells form, it is not possible to extend the network further and form larger-scale network structures that would significantly reduce the entropy in the mixed state, the other requirement for LCST behavior. However, the formation of DIPAwater-DIPA clusters will reduce entropy in its own right, much more than simply the formation of DIPAwater dimers, since these larger MCSs will have much higher moment of inertia and be harder to rotate than dimers.