In CPI, technological hazards coupling scenarios are mainly caused by the domino effects . Technological hazards coupling scenario is a common phenomenon during the propagation of domino effect. Fire and explosion are the main types of technological hazards that trigger domino effects in CPI . The fire thermal radiation, explosion overpressure, propellant fragments due to primary events may produce LOC events in adjacent process equipment that stores inflammable, explosive, and toxic materials, leading to secondary fires, explosions, or toxic cloud emissions . Common technological hazards coupling scenarios include: multiple fires , fire-explosion , fire-explosion-toxicant leaks .