We have previously shown that for the same and related ligands, and different metal salts, similar crystallographic structures with the rare space group (P622) form, marked by a variety of unusual morphologies that could not be indexed. These morphologies undoubtfully demonstrate how reaction conditions (i.e., metal ligand ratios, metal cations and anions, temperature, solvents) play dominant roles in shaping these crystals. Regardless of the reaction conditions, the nodes are six-coordinated octahedral complexes. This is in line with our observation in this current study of a unique crystal structure-morphology relationship. This relationship is based on the difference between the mathematically defined unit cell and its chemical reactivity. It is tempting to speculate on the generality of unexpected morphologies due to crystal facets that cross the large voids typically found in MOF structures. Our own ligand systems have yielded not only the above described stellate crystals but previously reported single crystals having morphologies of remarkable complexity. As a result, crystal forms that do not follow the conventional crystallographic rules can be found.