 Scientists with a project workload cannot be expected to keep up with the literature  Even if they strive to do so, their searching methods may be a long way from bestpractice (e.g. just popping keywords against PubMed has a dangerous level of falsenegatives)  Professional support for literature searching (as is generally available from Information Scientists in the larger pharma companies which extends to commercial database queries as well) is rare in an academic setting unless teams are fortunate enough to have library support  Teams may not have awareness triggers (i.e. automated alerts) in place