In this study we thoroughly investigated the structure and morphology of the doped hydrotalcites synthesized under continuous co-precipitation in a meso-scale flow reactor. The new synthesis method is proposed to overcome the limitations of the widely used batch co-precipitation: irreproducibility of the synthesis and significant variance of properties obtained in the batch co-precipitation due to lack of control over mixing in the process. The hypothesis was that the mixing time in the reactor should be commensurable to micromixing characteristic time. This was proven by obtaining a significantly more narrow distribution of the key property of the flow-synthesized materials -specific surface area, measured as BET surface area -as well as by higher degree of crystallinity and smaller particle sizes obtained in flow.