Table summarises the recent and relevant studies on electrochemical detection of nimesulide, revealing that the detection limits offered by our all-printed 3DPEC are on par with results obtained with more sophisticated electrodes. Notably, most such studies are reported only in buffer solutions to avoid fouling or corrosion and to increase the reproducibility, linearity range, and LODs, while our studies were performed in a more complex sample matrix. The 3DPEC fouling during consecutive electroanalysis in the sewage is moderate. The SEM micrograph in Fig. inset reveals a mediocre degree of electrode surface fouling after performing ten independent analyses and flushing the system between the measurements with PBS. At the same time, the DPV scans at 2 M nimesulide concentration and recorded after each cycle are shown in Fig. .