The SPR responses from five concentrations of the target compound (4-64 nM) were fitted to a 1:1 bio-interaction (BI) mdel (Langmuir fit model) utilizing TraceDrawer software. Association rate constants (ka), dissociation rate constants (kd), and maximum binding (Bmax) were fitted globally, whereas the BI signal was fitted locally. The equilibrium dissociation constant (KD) was calculated from the ratio kd/ka. Preparation of MON-based QCM sensors. Quartz crystal microbalance (QCM) sensors coated with a 50 nm silica overlayer (QSX 303, ∼5 MHz fundamental frequency) were purchased from Q-Sense (Sweden). Each sensor was cleaned according to the manufacturer's instructions. This protocol involved (i) UV/O3 treatment for 15 min (Bioforce UV/O3 cleaner, ∼9 mW cm -2 , λ = 254 nm), (ii) exposure to 2% w/w sodium dodecylsulfate solution for 30 min, (iii) copious rinsing with deionized water and drying under N2, (iv) a final UV/O3 treatment for 15 min.