As a first use case, we performed a systematic evaluation of reaction conditions for the formation of silver nanoprisms. The size distribution of the nanoprismsand thereby, their absorption properties are determined by the stoichiometric ratios of the silver source (AgNO3), the reductive component (NaBH4), the oxidative component (H2O2), the buffer (sodium citrate) and the silver concentration mediator (KBr). We selected a representative set of conditions from this five-dimensional continuous parameter space through Latin hypercube sampling. Using Chemspyd, we were able to quickly write the execution code, simply looping over all hypercube samples, and the required liquid transfer and stirring operations were performed automatically. Optical absorption measurements were carried out on our spectroscopic characterization platform. The resulting dataset of spectroscopic properties of the obtained nanoprisms is shown in Figure .