However, when applying these models, potential mechanistic breaks as well as utility of the chosen representations (descriptors) across the entire dataset have to be considered. Currently, the work mainly focuses on CPAs for which a vast number of reactions are reported. While this underlines the importance of CPAs as enantioselective organocatalysts, work exploring the mechanistic transferability of other catalyst classes should not be neglected in order to fulfill the potential that the application of ML in organocatalysis holds.