The performance of all of these parameter sets is summarized in Table . A number of parameter sets show excellent performance ( L min /n < 0.002) on both large and small targets, which are highlighted in bold. However, L min /n only requires a single trajectory frame to achieve a low loss value. All parameter sets that satisfy the more stringent criteria ( L avg /n < 0.002) were obtained with a maximum MLForce Scale value of 5000. To further probe the performance of Flexible Topology at this parameter value we ran an additional series of simulations (below the horizontal line in Table ). We find that the best performance is obtained by increasing the number of steps per cycle, but that excellent performance can still be obtained with as little as 200 steps per cycle, or 60 ps for each assembly trajectory.