The Vina Score which is an estimate of binding energy, the predicted value of LogBB which is an estimate of BBB permeability and the estimated Chemical synthesizability of selected molecules generated with STgrow4 are shown in Table . These molecules were selected for the following reasons. Molecules #1 and #2 were selected because they had the highest Vina Score among molecules with LogBB > 0.3. Molecules #3 and #4 were selected because they had the best Synthetic Accessibility among molecules with Vina Score < 9.0 and LogBB > 0.3. And molecule #5 was selected because it had the highest LogBB value among molecules with VinaScore <= 9.0. All five of these molecules were also classified as Blood-Brain-Barrier permeable by Swiss-ADME, had no violations of Lipinsky rules and were predicted to have high GI absorption by Swiss-ADME. These predicted properties indicate that the designed molecules are expected to have optimal pharmacodynamics, pharmacokinetics, BBB permeability and are likely to be synthetically accessible.