The global spread of multi-drug resistant bacteria is an alarming problem causing a threat to human health. The statistics from reputable sources such as WHO, CDC and World Bank have revealed the severity of treat that resistant bacteria can cause. They regularly publish reports which provide insights into the impact of resistant bacterial infections on public health domain. In line with the aim of preventing and addressing bacterial infections, CDC's lists of urgent treats, serious threats and watchlist species is periodically updates suggesting the dynamic nature of challenge and ever-evolving resistance among bacterial species. Various research endeavors are being made toward the development of novel antibiotics, but it comes with its own challenges.