Phages are by their number the most abundant biological entities in the biosphere . They and their protein components, involved in the interaction with bacterial cells, have been identified from different matrices (wastewater, soil, feces). Considering the small number of sequenced phages, most phage proteins cannot be identified yet, due to the scarcity of primary sequenced data, and the functionality of most of their proteins remains unknown. Thus, new phages should be isolated, and their genomes should be sequenced and compared to the metaproteomic data to discover new molecules and new effectors, thereby helping to predict also their functionality.