Based on our results it is clear that in order to truly delineate lipid dynamic, kinetic studies of lipid accumulation in Aβ proximity might be needed. Indeed, such approaches have been previously utilized for instance to follow surfactant metabolism is lung . We recently utilized such kinetic approach, in a imaging stable isotope labelling kinetic study (iSILK) where we followed the Aβ peptide deposition during Aβ plaque maturation . All other authors declare no competing financial interest.