Consequently, only a limited number of DNA molecules attach to the AuNPs through simple mixing, and they do so in an uncontrolled manner. This haphazard attachment prevents DNA molecules from effectively hybridizing with complementary DNA (cDNA) due to the strong interactions between DNA bases and AuNPs . Several approaches have been developed to overcome this problem, however, the procedures devised require time consuming stepwise addition of salt (around 10-50 mM each time), addition of surfactants, sonication, and freezing . Our work aimed at developing a fast, reliable, and scalable coating process capable of stabilizing and functionalizing AuNP in minutes.