The average SAScore of molecules in ChemBridge-MPO dataset is 2.79, while molecules generated by the pre-trained model have a lower average SAScore of 2.59. This suggests that molecules generated by CNSMolGen's pre-trained model generally have a lower synthetic difficulty and, compared to molecules in the pre-trained set, the synthetic accessibility scores of these new molecules have decreased. This result confirms that the CNSMolGen model performs well in generating molecules that are easy to synthesize.