In terms of ingestion, if microplastics from toilet paper enter the human body through the digestive tract, they can lead to gastrointestinal inflammation, and there is concern that they could accumulate in the body over time. Ingested microplastics may interfere with nutrient absorption or cause other digestive issues. Furthermore, once ingested or inhaled, microplastics can accumulate in body tissues. Over time, this bioaccumulation could lead to chronic exposure to the toxic chemicals associated with microplastics, potentially causing long-term health effects. The presence of foreign particles like microplastics in the body can trigger an immune response. Persistent exposure may lead to chronic inflammation, which is associated with a range of health problems, including cardiovascular diseases, autoimmune disorders, and even cancer.