Owing to the chiral porous skeleton and PA detection capability of PRBT and PSBT, enantioselective fluorescent sensing toward chiral nitro-aromatics were further explored. The enantiomers, (R)-1-(4-nitrophenyl)ethan-1amine (RNPEA) and (S)-1-(4-nitrophenyl)ethan-1-amine (SNPEA), were selected as the interested compounds. As shown in Figure , the PL intensity of PRBT in MeOH had gradually decreased with the addition of RNPEA, in which the emission decrease was obviously slower for SNPEA relative to its mirror-imaged analogue (Figure ). Similar to the detection of PAs, the luminescence lifetime of chiral POPs was also obviously attenuated suggesting a dynamic quenching process (Figure ). The K sv constants for PRBT were calculated to be 94.2 M -1 and 70.4 M -1 for RNPEA and SNPEA (Table ), respectively, which afforded the quenching ratio [QR1 = K sv(RNPEA) /K sv(SNPEAl) ] of 1.36. Additionally, the chiral POP PSBT displayed distinctively opposite selectivity, which suggested a similar quenching ratio [QR2 = K sv(SNPEA) /K sv(RNPEAl) ] of 1.29 relative to its analogue. These quenching ratios were comparable with those reported BINOL-containing chiral porous polymers for enantiosensing (Table ) . And the enantio-selective sensing performance of this developed chiral macrocyclic POPs required to be further improved in the future.