In 2023, the Baran's group developed a Ni-electrocatalytic enantioselective doubly decarboxylative cross coupling (dDCC), radicals that are derived from malonate half amide and aliphatic acid were generated via single electron-transfer (SET) from Ni(I) to redox-active aliphatic acid NHPI (Nhydroxyphthalimide) esters (Figure , 1) . Recently, the Yang's group disclosed a cooperative photoredox/Fe/chiral primary amine triple catalysis protocol to construct quaternary stereocenters by decarboxylative cross-coupling of 1,3-dicarbonyl compounds with primary alkyl radical, which was generated from the reduction of aliphatic acid NHPI esters (Figure ) by an iridium photocatalyst .