To assess the effect of scrambling on the gas sorption properties of the cages, the uptake of N2 at 77 K and CO2 at 195 K was measured. We have also measured the previously unreported gas sorption properties for the non-functionalised, homoleptic cage [Cu4(L)4]. Previously, we reported the gas sorption isotherms for the homoleptic cages [Cu4(MeOL)4] and [Cu4(CH3L)4], and those data are included here for comparison. Figure displays the N2 adsorption isotherms for both families of cages measured at 77 K (the desorption data, and isotherms for CO2 are provided in the supporting information, Figs. ). While the homoleptic cage [Cu4(MeOL)4] does not present N2 uptake at 77 K, [Cu4(CH3L)4] displays the steep uptake associated with microporous materials, and BETSI was used to determine a BET surface area of 380 m 2 /g. Here, all of the scrambled materials present Type H4 isotherms. As x increases for [Cu4(MeOL)4-x(CH3L)x], the uptake of N2 is shown to improve significantly for x ≥ 3. For [Cu4(MeOL)(CH3L)3], the uptake at P/P0 ≈ 0.9 is of 85.8 cm 3 /g, compared to 5.8 cm 3 /g for [Cu4(MeOL)2(CH3L)2], and 117.4 cm 3 /g for [Cu4(CH3L)4]. This is reflected by an increase in the BET surface areas as x increases (Fig. ), reaching a maximum for the homoleptic material [Cu4(CH3L)4]. This trend, which mixed cages show gas uptake that lies between that found for pure homoleptic cages has been observed for tetrahedra based on [Cp3Zr3] nodes and cuboctahedra containing [Mo2] paddlewheels linked with functionalised isophthalate ligands. In addition, we measured the N2 uptake for the physical mixture [Cu4(MeOL)4] + [Cu4(CH3L)4], and found that it displayed superior gas uptake to the scrambled material [Cu4(MeOL)2(CH3L)2] (Fig. ). We propose that this is due to the presence in the physical mixture of the pure homoleptic cage [Cu4(CH3L)4], which may not be present to a large extent in the scrambled material [Cu4(MeOL)2(CH3L)2]. The uptake of CO2 at 195 K, of all of the members of the family [Cu4(MeOL)4-x(CH3L)x], is found to be Type I, with a range from 109.9 cm 3 /g to 127.7 cm 3 /g at P/P0 ≈ 0.9 for [Cu4(CH3L)4] and [Cu4(MeOL)3(CH3L)], respectively. In this case, the scrambled materials do not greatly improve the CO2 sorption capacity with respect to their homoleptic analogues (Fig. ). Post-sorption analysis of the scrambled cages [Cu4(MeOL)3(CH3L)],