Co-formulants and adjuvants and can have individual toxicity to non-targets , can synergise with active ingredients ) and can synergise with other stressors . Each pesticide formulation and adjuvant will have its own unique mixture of ingredients (active ingredients/effective adjuvant components and coformulants), potentially giving it a unique toxicity to non-target organisms . Non-target exposure to co-formulants and adjuvants can be very high , so any undetected toxicity they could confer to an application could be highly consequential.