In this section we will discuss current targeted applications of tough hydrogels. Figure gives an overview of the articles referenced and discussed in the previous section and the respective applications of the presented tough hydrogels. To understand the interactions in the tough hydrogel that renders them suitable for load-bearing applications, structureproperty relationships are at the core focus of investigation of 50% of all cited publications here. This includes changes in the hydrogel precursor formulation (typically concentration of monomer/polymer, cross-linker, nanoparticles, etc.) and/or variation of process parameters, such as temperature, immersion time, and others.