Beyond the direct synthesis, alternative synthetic methodologies such as post-synthetic linker-exchange (PSLE) allows to obtain materials that are not available by common routes. For example, partial exchange of the 2methylimidazole by 5,6-dimethylbenzimidazole has been achieved through a shell-ligand-exchange-reaction (SLER), whereas anchoring of fluorinated molecules has been possible through thiol-ene click reaction. However, this approach is typically effective only at the surface. Vapour-phase ligand exchange (VPLE) has also been used to incorporate different imidazole derivatives, although it is limited to certain imidazoles, resulting in some cases in a transformation into dense phases. Nevertheless, a major limitation of postsynthetic strategies is the incorporation of additional synthetic steps, which hinders a scalable process and therefore a commercial use.