Addition of 5 equiv. of triethylamine (TEA) lead to the neutral E isomer of PAT 1 and after 1 the aggregate is formed again as visible by the significantly broadened and red-shifted absorption (Figure right). In this way, a fully reversible and light-independent pH responsive switching between aggregated and dissolved PAT 1 is enabled without changing the configuration of the double bond. Further, testing irradiation in the presence of 10 equivalents TFA resulted in fully viable reversible photoswitching with NIR and orange light between 1-E-H + N and 1-Z-H + N, respectively, demonstrating also independence of the photoresponse from moderate pH changes. Subsequent addition of 15 equivalents of TEA to 1-Z-H + N and Z to E photoisomerization with 565 nm light led to formation of the aggregate again, proving that also a combination of acid/base induced switching and photoswitching allows to reversibly control aggregation of PAT 1 (see Supporting Information for details).