The present parser has only two hard rules enforced in the CDXML file parsing: (1) the label used for dictionary-like lookup of structures must be bold-faced, not chemically interpreted, and placed below the structure and (2) the parsing is deterministic with respect to the drawing, however different ways of depicting the same configuration may result in different parsing results; It is the responsibility of the user to verify that the minimization after parsing yields expected results. For example, changing the directionality of stereobonds may produce results that are not identical (see Figure ).