Finally, reaction cycles that directly impact colloidal interactions, for instance by rendering colloids temporarily solvophobic, can form undesirable kinetically trapped irreversible aggregates . Recent work by the Guan lab has utilized electrochemical reactions to overcome some of these limitations . Here, an electrochemical redox couple stimulates assembly of redox active molecular building blocks. This approach enables rapid assembly and autonomous disassembly of molecular hydrogels. Aside from chemical fuels that directly react with colloid surface ligands, reaction networks that generate pH transients have also been utilized to program autonomous colloidal systems . Seminal work by Heuser et al. created pH spikes by mixing a basic buffer with a proton releasing organic species, which were used to form transient colloidal assemblies . More complex transient pH cycles have since been developed that utilize enzymatic reactions and pH oscillators .