Since MEW scaffolds are used for biomedical applications, they need to accommodateand ideally enhance -existing imaging capabilities used for visualizing tissues and cells. This includes observing real-time changes in cellular interactions with the scaffold. However, due to challenging thermal processing requirements, successful methods for imparting fluorescence onto MEW scaffolds remain limited. Fluorophores embedded within the melt must withstand elevated temperatures for sustained periods, which degrades many common fluorescent molecules. A recent study by Wu et al. introduced fluorescence to MEW scaffolds through the incorporation of fluorescent nanodiamonds which provide a single emission band . Another study used a biomaterial ink specifically designed for MEW hydrogels that chemically binds the fluorophore when placed into a rhodamine solution . However, fluorescent molecules with additional customizability over the emission ranges may offer significant advantages for biomedical applications of fluorescent MEW scaffolds.