In this study, we used mouse in vivo PK data for plasma and brain obtained for 103 compounds as described above for 4 (A to D) projects in the TEIJIN Pharma in-house database. These compounds' structures cannot be disclosed due to the patent problem. For iv administration, 96 compounds were examined in projects A and C, and for po administration, 7 compounds were examined in projects B and D. The units of measured concentration were nmol/L for plasma and nmol/kg tissue for brain, and these data are presented on a log10-transformed scale. The lowest limit of quantification was 1 nmol/L, and values less than 1 nmol/L were considered as 0.