However, it is also interesting to note that even though Alignment studies showed 83% and 96% identity in case of Model 1(obtained using the template 3E9S) and Model 2(obtained using the template 2A5I) with PlPro and 3CLPro respectively, the binding cavity interactions/milieu were very similar in the 2nd case inspite of not much conserved amino acid residues,and in the former case, the binding cavity showed certain similarity in terms of the cavity milieu, however the intensity varied due to multiple, additional stability.