Having established an enantioselective SN2'-like addition to prochiral molecules, we turned our attention to the selective arylation of molecules with pre-existing stereogenic centres. This would establish a method which would be useful in complex molecule synthesis beyond providing starting-material-type building-blocks with a single stereogenic centre. As an initial test of this approach, we first performed asymmetric addition on a naproxen derivative, and we were delighted to obtain 56 featuring two contiguous stereogenic centres in 86% yield as a 13:1 ratio of diastereoisomers (Figure ).