The calculated material and energy flows across the proposed process were summarised into gated LCIs. From the process models, a realistic plant capacity for β-pinene-based paracetamol manufacture using locally sourced CST in a European plant was estimated as 1 tonne/day. The environmental impacts associated with this process were quantified via cradle-to-gate LCA, and worst-case-scenario LCIA results were obtained that are expected to improve with further process development. This must be acknowledged when benchmarking against LCAs of conventional paracetamol manufacture, which were not available at the time of this study.