Pharmit 37 is used to perform pharmacophore search on the DUDE benchmark. Search databases are built from the relevant conformational ensembles of the active and decoy compounds of each DUDE target. Due to the large number of conformers required, only RDKit conformer generation was evaluated for this task. The provided reference crystal structure is used to elucidate all possible interacting features (hydrogen bonds, hydrophobic interactions, charge interactions, and aromatic interactions) between the ligand and receptor.