All novel zirconium-ellagate frameworks (SU-103 -SU-112) were synthesized from a mixture of 32 mg zirconyl chloride octahydrate, 60 mg ellagic acid, 2.5 mL water, 1.0 mL acetic acid and 1 mL / 1 g of an OSDA. Each mixture was heated for 1 h at 160 °C. The OSDA used for each MOF is presented in Fig. and in Supplementary Fig. . Crystallinity was confirmed by powder X-ray diffraction (PXRD, Supplementary Fig. ). To demonstrate the rapid development of MOFs combined with fast 3D ED structure determination, SU-106 was synthesized and its structure was solved in a single day (5 h 40 min). Synthesis was completed within 3 h 30 min, including lab preparation and measuring reagents (1 h 15 min), heating the reaction (1 h), washing and drying the product (1 h 10 min). PXRD was then performed within 50 min. TEM sample preparation took 35 min, and finally 3D ED data collection, processing and structure solution was complete in 50 min.