It could be argued that the low electrostatic interactions are due to the thermal movement of the adsorbate inside the MOF. To assess the influence of guest dynamics on the electrostatic interactions, we calculated autocorrelation functions (ACFs) of the dipole orientation for each guest molecule (see Section 1.2.5 of the SI for details). At 300 K only CH 4 and CH 3 Cl exhibit a decay of the autocorrelation to below 0.2. All other guests show autocorrelation values of above 0.5 during the 50 ps analyzed (see Section 3.8 of the SI) and are therefore almost frozen in their respective orienta-tion. The thermal movement of the guests can therefore not be responsible for the low electrostatic interactions. At 400 K all guests exhibit autocorrelation values of below 0.2 after 50 ps. In the temperature range used here, we therefore cover almost frozen guest orientations as well as almost liquid-like guest states. By comparing the electrostatic contributions to the adsorption energy at 300 K and 400 K, we can conclude that the guest dynamics do slightly lower but do not average out the electrostatic interactions. The vdW interactions however are affected by the increased temperature in the same way. Also, the autocorrelation of the guest orientation does not follow the trend of the dipole magnitude but is rather dependent on the bulkiness (not to say diameter because perfectly spherical molecules would probably not exhibit this dependence) or polarizability. The faster decay of the autocorrelation value of CH 3 Cl in comparison to CH 2 Cl 2 also explains the slightly smaller electrostatic contribution to the MOFguest interaction visible in Figure . Overall, we conclude that the thermal motion of the guest molecules is not responsible for the unintuitive domination of the vdW interactions.