A key problem in CO 2 reduction on Cu is fine-tuning its selectivity towards long-chain valuable products. CARE is able to reproduce selectivity trends, for instance, for C 2 products, ethylene and ethanol are typically observed but in the C 3 fraction only 1-propanol is observed and the route of propylene is blocked. CARE was used to reproduce the paths starting from two key intermediates, allyl alcohol and propionaldehyde. The selected paths leading to 1-propanol (Fig. ) and its competition with propylene (Fig. ), previously evaluated at the DFT level in Ref. have been taken to analyze selectivity. The results obtained with CARE are comparable with those obtained with DFT, demonstrating the capacity of CARE to identify trends. When subjected to alkaline pH (Fig. ) and reductive conditions (Fig. ), thermodynamically favorable pathways towards the formation of 1-propanol are identified. These findings align with 21 previous DFT studies and highlight the preferential formation of 1propanol over propylene. As for the selected paths at zero applied potential (U =0 V SHE ) (Supplementary Fig. ) a shift in trend occurs, being in this case the path from allyl alcohol to propylene more thermodynamically favourable than that to 1propanol, in line with DFT studies .