The H2 isotherms for Cu I Zn-MFU-4l from 193 to 313 K were fitted with the Langmuir-Freundlich equation using temperature independent parameters (Figures and). We note that the simulated isotherms generated from the resulting fit parameters match well with the corresponding experimental isotherm at these temperatures, indicating minimal temperature dependence of the thermodynamic parameters for the adsorption sites in the Langmuir-Freundlich model for the examined temperature range. Using these fit parameters, we plotted the logarithm of pressure versus reciprocal temperature (i.e., ln P vs 1/T, a Clausius-Clapeyron plot) for various H2 loadings with 0.05 mmol/g increments for the 193-313 K range, finding an excellent linearity with R 2 > 0.999 up to the highest H2 uptake at 1 bar and 313 K (Figure ). The Clausius-Clapeyron analysis revealed a nearly constant ∆Hads value of -33.3 kJ/mol with respect to loading up to 0.6 mmol/g of H2 uptake (light blue line in Figure ), similar to the reported value of -32.3 kJ/mol determined using isotherm data recorded at 163-193 K. Next, we performed the same analyses for the isotherm data while dividing them into four sets with 20 K windows (203-223, 233-253, 263-283, and 293-313 K). The Clausius-Clapeyron analyses for these various temperature windows result in similar ∆Hads values within ±1 kJ/mol, with the ∆Hads values estimated for higher temperatures being slightly stronger (Figure and Table ). Slight increases in the magnitude of ∆Hads at higher temperatures could be explained by the difference in heat capacities between the gas phase and the adsorbed phase due to switching of the translational freedom in the gas phase into the vibrational freedom in the adsorbed phase. Upon recognizing that ∆Hads for H2 adsorption onto a series of Cu I M-MFU-4l slightly depends on temperature on the order of 2 kJ/mol in a 120 K window, we selected a different temperature window for each Cu I M-MFU-4l framework for the Clausius-Clapeyron analysis.