The as-prepared Pd/SO3H-MIL-101(Cr) catalyst has general catalytic activity and selectivity in hydrodeoxygenation reaction of vanillin at 100 •C under 0.5 MPa H2. Besides, Chang's group reported the use of synthesized Pd@HPCs by the wet impregnation method derived from MIL-101-NH2 MOF as a highly active and stable catalyst for hydrodeoxygenation (HDO) or hydrogenation reactions of various biomass-derived organic compounds at 80 C under 0.5 MPa H2. Whereas supported noble metal Pd doped MOF were numerously prepared by impregnation, most of the Pd nanoparticles may be loaded on the surface of the frames and small metal nanoparticles (NPs) aggregate easily and lead to poor thermodynamical stability during the reaction, resulting the catalyst's activity was declined. Tetrakis(triphenyl phosphine) palladium (Pd(PPh3)4) is a well-known homogeneous coordination catalyst and demonstrates extensive applications in organic reductive and cross-coupling transformations. However, Pd(PPh3)4 is an air-sensitive homogeneous catalyst that not only suffers from difficulties of separation and recyclability but also often causes catalyst deactivation in the process of reaction. In the past, using a simple one-pot method to obtain generation of palladium nanoparticles from Pd(PPh3)4 and make recyclable palladium catalysts through removing PPh3 ligands and subsequent (MeO)4Si or (i-PrO)4Ti supporter gelation by treatment with water. However, the palladium catalysts often suffers from problems such as low reactivity, palladium uneven distribution, and poor recyclability.