Nucleation and growth mechanisms of ZIF-8 have been studied during the last decade by different approaches; however, most of the studies employed different synthetic conditions for the synthesis, meaning different supersaturation regimes, among other variables such as temperature, counter ions, solvent, time, etc. Individually, each study provides information about the underlying mechanism operating in the proximity of the synthetic conditions explored. A more comprehensive understanding of nucleation and growth of ZIF-8 can be reached by organizing the reports according to the supersaturation condition employed, as depicted in Figure . Since the supersaturation condition is not easy to establish from experimental conditions reported, the discussion will be carried out in terms of the molar ratio upon mixture between the species involved (Zn 2+ , hereinafter Zn, for simplicity, and 2-methylimidazole HmIm) and the solvent (Sv) (Zn : HmIm : Sv).