The P. aeruginosa CFI-004-CRCN strain, which does not degrade the crosslinked gelatin layer was tested as a negative control (Figure ). P. aeruginosa strains PAO1 and CFI-004-CRCN are susceptible to phage INV-03 as tested by their growth analysis by using various dilutions of the phage (Figure ). Indeed, the growth of both strains is limited and then completely inhibited with increasing concentrations of phage INV-03. This successful addition of a therapeutic layer containing bacteria specific phages demonstrates a potential architecture of multilayered smart wound dressings. In a context of antibiotic resistance, this system thus sounds promising.