In the DDR1 case, we can also conclude that the latent space is consistent, as with the other cases. We also demonstrate the correlation between latent variables and both DFG labels and salt bridge distance. In the main text, we have shown that across different states we have distinct properties for the DFG label and the salt bridge distance (Figure ). This is a useful feature when af2rave is used for structure generation, but for enhanced sampling or structural projection purposes, it is important that the latent variables can be interpretable to some degree.