Because the net effect of noise is an overpopulation of the antibonding 𝜋 * orbitals (Figure ), the charge distribution is slightly skewed in favor of C (Table ). A second reason for the negligible effect of our mitigation scheme in the case of HCN is that our calculations are based on sufficiently many, 10 6 , simulated measurements, which effectively removes asymmetric errors in the 1-RDM. The main advantage of our error mitigation approach in this example is ensuring the correct number of electrons (Table ).