We calculated the QED as an empirical and well-established measure of drug-likeness. QED is based on eight molecular properties relevant to determining drug-likeness: logP, HBA, HBD, PSA, nRotB, number of aromatic rings, and number of structural alerts . The weighted geometric mean of these properties is the resultant QED that goes from zero (worst) to one (best). The suggested threshold for the attractive compounds is 0.67. This value or higher is desirable for drug-like compounds. QED was calculated with RDKit, which is available in the Chem module.