Surprisingly, with a lower catalytic amount 20% of K2CO3, after 4 hours, a 98% yield of BHMF could also be obtained. We could also find that the air was necessary for this reaction since the reaction only gave 16% BHMF even with a modified longer reaction time of 5 hours without air compared with the 98% BHMF with air. When the reaction temperature decreased from 80 °C to 25 °C, the BHMF yield dropped from 98% to 19% respectively. AC did not have the comparative efficiency with the MS 4Å. Furthermore, the organic solvent THF did not accelerate the reaction and only 5% BHMF was water in a large-scale synthesis. We also purified the BHMF and confirmed the purity in HPLC after purification and its H proton information according to the H-NMR spectrum. Surprisingly, the oxidation of DHMF to BHMF could be carried out efficiently with a 98% yield using a catalytic amount 10% of K2CO3 in H2O, under an open-air system without any additives. To the best of our knowledge, this discovery was not reported yet till now.