The crossdock default2018 model shows a slight reduction in performance on the cross- docking task, while the general default2018 and redock default2018 show a slight increase in performance for crossdocking (Figure , S7b, and S8b). Finally, we distill the ensemble composed of all models with a Default2018 architecture, referred to as "All De-fault2018 Ensemble," into a single Default2018 model. This distilled Default2018 model shows the highest performance of any Default2018 distilled model (Figure ). The distilled model has higher performance than any single non-distilled Default2018 model and higher performance than any ensemble of Default2018 model on both redocking and crossdocking tasks. This distillation shows the greatest decrease in docking time while nearly maintaining the performance of the full ensemble on both docking tasks.