(2) vw⊕el,V (z) includes: (1) changes in the DS -conformational and orientational distribution compared to that of DS 0 due to electrostatic interactions of the DS -head group with water and the C 12 E 6 head groups, (2) the accompanying energetic effects from introducing the DS -partial charges, (3) the accompanying entropic effects due to structuring of water and the C 12 E 6 head groups around the DS -partial charges.