A short, single-stranded DNA or RNA molecule known as an aptamer has a high affinity and selectivity for binding to particular target molecules . The systematic procedure known as SELEX is used to select these compounds. Because of their comparable binding properties to antibodies, aptamers are frequently used interchangeably, but they also have unique benefits such as simpler manufacturing, less immunogenicity, and increased thermal stability. Aptamers are used in many contexts, such as biosensors, medicinal agents, and diagnostic instruments.