There is pressing urgency to better understand the immune system behavior after SARS-CoV-2 infection. In light of this global effort, we discovered putative therapeutic targets of the immune system by screening 1,588 high-confidence nodes into human tissues using scRNA-seq data. Ziegler et al. discovered ACE2 and TMPRSS2 coexpressing cells in nasal goblet secretory cells, lung type II pneumocytes, and ileal absorptive enterocytes . None of these cells was exposed to the novel coronavirus but the analysis of the Alexandria Project data represents a large effort to characterize this immunopathology.