The funding of the challenges themselves will be shared among interested funders and participants. Funders, such as a disease foundation or a company, could support challenges of particular interest to them. As CACHE matures, participants will be expected to help defray some portion of percompound costs (including synthesis/purchase and assays) using their own funding. To facilitate this, CACHE will develop a transparent cost structure that can be used in funding applications. CACHE aspires to be able to subsidize the cost of participation for participants that agree to share their methods, code, or methodologies.