The results of individual simulations, one with Λ-[Ru(bpy) 3 ] 2+ dissolved in liquid SPC/E water solvent, and another simulation with ∆-[Ru(bpy) 3 ] 2+ dissolved in liquid SPC/E water solvent, show that these enantiomers migrate in opposite directions, according to their opposite pitches (see Fig. ). The counterion Cl -is also present in the [Ru(bpy) 3 ] 2+ simulations. Simulation parameters and details of the force fields and boxes employed are provided in the Supporting Information.