MOFs are prototypes of the reticular chemistry concept, in which well-defined building blocks are stitched together to form porous 3D frameworks. In the simplest case, two building blocks are used, linkers (typically di-or higher-topic organic molecules) and connectors (typically metal ions or metal/oxo clusters). Up to date, a huge variety of MOFs has been synthesized and characterized, with the most frequent applications in the fields of gas adsorption and separation, sensing, drug-release, proton conductance in fuel cells, catalysis, water splitting, and many others. In contrast to COFs, where the 2D versions are more prominent than their 3D counterparts, 2D MOFs with atomically thin layers coupled by van-der Waals-interactions areto daterather exotic and have been reported in few cases only. However, the instances of such layered system reported so far promise an interesting bridge between chemistry and physics, offering materials with interesting electronic and magnetic properties.