While Friedel oscillations have traditionally not been attributed to the chemical properties of nanoparticles and surface chemistry, recent studies have begun to explore this possibility. Various theoretical models of FOs, such as a widely used Hyldgaard and Persson theory, are being used to describe the spacing between adsorbates. One has to bear in mind, that in the case of molecular adsorbates, the dipole-dipole and dipole-mirror dipole interactions become important especially at separation distances below 3 nm. Therefore, an appropriate theoretical model should take this into account.