We note that this validated ME-cell could offer a realistic testing platform for new catalyst materials in real electrolyser environments. While rotating disk electrode voltammetry is commonly used for catalyst screening due to its practicality and use of small quantities of catalyst material, the results from this technique often do not reflect measurements in membrane electrode assemblies. The 0.14 cm² active area of the ME-cell allows for the production of electrodes using smaller quantities of material, compared to those produced for a typical ≥ 5 cm² active area cell, making it particularly useful for screening novel catalysts, whose synthesis is usually limited to a milligram scale in the early development stages.