In order to truly leverage the power of AWS, for example to launch 100 cloud computing instances to process hundreds to thousands of MS run files at scale, we have developed the AMZTPP system. It enables users to process any number of MS runs in a highly configurable manner, automatically uploading the data to AWS storage, automatically launching and terminating worker instances, and copying the data back to the local computer in a highly configurable manner. The system is complex, but can be installed locally with some effort or used trivially via TWA.