The original data sources of Reactions 1 and 2 reported the estimated 𝑘 liq along with the 𝑘 obs . However, the majority of the studies only reported the 𝑘 obs , which are assumed to be diffusion-controlled to a certain extent. Since the true 𝑘 liq could not be determined for those reactions, we fitted our functional form to the experimental 𝑘 obs data for the fitting method described in Section 2.2. We did not separately account for the diffusion effects in our method as it is challenging to make accurate estimations of 𝑘 diff for the reactions investigated in this study and diffusion effects become negligible near a critical temperature of a solvent. It is shown that our method can still accurately reproduce the experimental rate constants of the diffusion-limited reactions as further discussed in the results section.