Upon scanning of the binding site FP-score suggests that Ser-A-289, Phe-A-363, His-A-449, and Tyr-A-473, falls in the Anchor-category residues. In the Transient-category residues, Arg-A-288, His-A-323, Tyr-A-327, and Lys-A-367, with two residues in the Accessible-category Phe-A-282, and Leu-A-469. The rest of the binding site are less prioritized for development of high affinity agonist, (Figure