In summary, we have evaluated the relevance of generic CG models for the characterization of the dipolar NMR relaxation rate R 1 . Our results obtained from a PEG-H 2 O mixture show that R 1 calculated from a G-CG model follow the same trend as R 1 from a reference AA model, but with a systematic offset. For PEG, the main origin of the offset on R 1 is the absence of intra-monomer contributions, which is an intrinsic feature of G-CG models. The second reason for the offset are the differences in the typical distances between spin carriers between G-CG and AA models, which affect both inter-monomer and inter-molecule contributions. We have shown that the offset in R 1 between G-CG and AA simulations can be corrected exactly by re-introducing hydrogen atoms at their equilibrium positions from the G-CG trajectory using a RCG procedure. Our results obtained from the generated G-CG-H trajectories compare well with the experimental data. Therefore our study is the first step toward the development of joined experimental and numerical NMR studies of complex systems that are not accessible on the AA level, such as long polymer chains and hydrogels.