In the light of the different definitions of turnover number (TON) and its frequency and the misrepresentation of catalytic cycle (CC) and its frequency, this study has shown that all parameters are different; while the first-order catalytic rate constant (a zero-order Michaelian value) is the same for different concentrations of the same enzyme under the same conditions, TON and CC frequencies vary. The TON and CC and their corresponding frequencies are valid, distinct kinetic parameters. All the enabling model equations have