-Set of 215 2D physio-chemical descriptors implemented in RDKit (based on the "molfeat" package implementation). The molfeat implementation has six additional features compared to the RDKit descriptors. These features include the number of atom stereocenters, number of unspecified atom stereocenters, number of bridgehead atoms, number of amid bonds, number of spiro atoms, and number of structural alerts present in a molecule (based on the structural alerts defined in the RDKit Quantitative Estimate of Druglikeness -QED-44 score package).