Geranyllinaloyl diphosphate (GLPP). Woodside's procedure was employed to prepare GLPP . Tris (tetrabutylammonium) hydrogen pyrophosphate trihydrate ((Bu4N)3P2O7H) was prepared as follows. Disodium dihydrogen pyrophosphate (3.1 g, 14 mmol) was dissolved in 25 mL of 4% (v/v) aqueous ammonium hydroxide. The clear solution was loaded onto a 2 × 30 cm column of Dowex AG 50W-X8 cation exchange resin (100-200 mesh, H + form), which had been prewashed with deionized water. The free acid was eluted with 150 mL of deionized water, and the eluant was immediately titrated to pH 7.3 with 25% (w/w) aqueous tetrabutylammonium hydroxide (15 mL). The resulting solution (approximately 190 mL total volume) was dried by freezing the solution in a dry ice isopropanol bath and lyophilizing for approximately two days to yield a hygroscopic white solid (9.8 g, 77%), which was stored over phosphorus pentoxide until required.