One may ask whether self-assembled, noncovalent assembly systems may propagate information (3). In the realm of GARD, we use assembly composition as a useful descriptor of the state of a molecular assembly. Composition is a vector of the normalized amounts or concentrations of every compound type within the demarcated volume of a molecular network. The dynamics is then translated to a trajectory in multidimensional composition space . Constancy of molecular composition along the growth of a protobiotic mutually catalytic assembly is a criterion for reproduction. Chemical composition is thus a substitute for sequence information , and is simile to certain types of epigenetic information in nowadays cells .