To establish a system with variable electrode temperature and hydrodynamics, we expanded the high throughput analytical electrochemistry (HT-ANEC) screening system to include a Peltier heating element that is electrically isolated and thermally coupled to the planar working electrode. To characterize the behavior of the cell with a heated working electrode and electrolyte flow, we invoked multiphysics modeling to establish the distribution of electrolyte flow rate and temperature throughout the working electrode chamber (Figure ). The design of the cell varies slightly from our previous report on the effects of hydrodynamics on Tafel slopes to allow for a thermocouple to be placed inside the working compartment to monitor internal temperature. We measured internal and outlet temperatures at five temperature points with surface heating (SH) to evaluate the degree of global heating of the system. At a surface temperature of 60 °C, we experimentally measure an internal temperature of 36 °C ± 1.1 °C and an outlet temperature of 26.8 ± 0.1, which supports our goal of mitigating bulk electrolyte heating.