It was reported earlier that the reaction of BODIPY 665/676 with peroxyl radicals (kBODIPY in R.9, Table ) has a higher kinetic constant than the formation of lipid hydroperoxides (k3 in R.3, Table ). Our results show, however, that although kBODIPY was two times higher than k3, the kinetic rate of the reaction between BODIPY 665/676 and peroxyl radicals is 4.5×10 7 times slower than the hydroperoxide formation, which is due to the high initial concentration of lipid substrates (see Supplementary materials). This finding explains, why our simulation showed that at the low concentration working range (≤ 50 µM), BODIPY 665/676 does not influence the formation of lipid oxidation products. Using a 10 4 higher concentration of BODIPY 665/676 (500 mM) our simulations showed a higher reaction rate than hydroperoxide formation, resulting in a slower lipid oxidation rate (Figure ). The simulations further showed that the differences in the experimentally obtained kinetic curves between emulsions including 0, 1, or 50 µM of BODIPY 665/676 (Figures &) could not be attributed to the concentration of BODIPY 665/676.