Albumin is considered a biological fouling standard and often used in test of electrode stability. As a potential antifouling agent it was deposited directly, and in this way did not present any protective properties. Electrodes in which albumin was mixed in a layer of PEGDE hydrogel were also prepared and characterized. The results in this case were analogous to the ones obtained with hydrogel, however the layer was less stable, and fragments of the coating tended to detach during measurements.