NMR relaxometry can provide information on paramagnetic as well as diamagnetic (e.g., proteins) compounds in solution . Blood is one of the attractive biological specimens for relaxometry studies. By probing the T 2 relaxation of water protons, NMR relaxometry of blood samples has been shown to hold great promise in the diagnosis and prognosis of metabolic disorders (insulin resistance, dyslipidemia), infections (candidiasis, malaria) and hemostatic disorders . Furthermore, relaxation of water protons in blood can provide valuable information about blood proteomes as water protons form hydrogen bonds with proteins, lipoproteins, and metabolites, affecting spin relaxation. While the contribution of macromolecules (e.g., proteins and lipoproteins) to proton relaxation is considerable, the influence of small metabolites (e.g., glucose and amino acids) on the process can be neglected due to the fast molecular motion, leading to inefficient dipolar relaxation . This may allow us to observe inflammatory-induced protein profile variations, independent of minor metabolites whose concentration may vary in an unrelated manner. Although variation in the molecular weight profile of blood proteins also affects the relaxation rate, in general, a linear correlation between protein concentration and relaxation rate is expected due to slower rotational and diffusion mobility of macromolecules . Consequently, the existence of a strong correlation between proton relaxation times and protein content makes T 1 and T 2 values promising biomarkers .