TMB nanoparticles have shown promise in nanomedicine as multifunctional components of radiation therapy and theranostics. Both FeB and NiB nanoparticles have low cytotoxicity with a half maximal inhibitory concentration of 82 mg/mL for pulmonary alveolar cells . In addition, TMBs degrade at physiologically relevant pH levels measured in lysosomes and thus should not accumulate in the body . Due to their magnetic properties, TMBs can be simultaneously used as contrast agents in magnetic resonance imaging (MRI) and as a cancer treatment via magnetic hyperthermia . Amorphous NiB-coated Au nanocubes were shown to provide superior radiation tolerance when compared to silica, which makes them promising coatings for nanoparticle-enhanced radiation therapy and as delivery vehicles for the non-radioactive isotope 10 B for neutron capture therapy . The combination of these properties with a plasmonic core could enable multimodal imaging such as surface enhanced Raman and MRI .