Overall, the Martini 3 model has membrane properties compatible with the Martini 2 version. Martini 3 lipid models are now able to distinguish between lipid tails that differ by two carbon atoms which leads to certain differences between the Martini 2 and 3 models of the typical plasma membrane (see Table ). For example, the Martini 3 model has a lower area per lipid for both leaflets, indicating improved lipid packing.