To further analyse the effect of precursor design on the reaction outcome, we defined each precursor as either 'rigid' or 'flexible' based upon chemical intuition, and counted the number of aromatic rings each had (Table ). We then simplified the reaction outcomes into three classifications -(i) clean formation of a cage either as a single topology or as a mixture of topologies (Figure (a) and (d)); (ii) formation of a cage either as a single topology or as a mixture of topologies with full conversion, but with insoluble precipitate present (Figure (b) and (e)); and (iii) precursor combinations where no cage topology was identified (Figure (c) and (f)).