Classical molecular dynamics (MD) simulations of biomembranes are nowadays increasingly used in various applications, ranging from molecular cell biology to lipid nanoparticle formulations for vaccines. Such applications are expected to increase further because MD simulations are becoming more accessible to a wider audience thanks to tools streamlining the simulation workflow, such as CHARMM-GUI and Schrödinger-Maestro combined with Desmond, and impressive performance of widely available GPU-computing hardware.