We assumed that the modest size and number of concaves on the GNB surface would play critical roles in visible droplet formation. The stabilized, invisible small droplets from the GNB surface enabled the aggregation and growth to form the droplets. Contrarily, convex shape of the GNRs and GNPs did not contribute to the formation of the droplets. The NIR-laser irradiation drove the dissolution of the visible droplet, although it might have driven its reformation (Figure ). These observations indicated the significance of the local convex/concave in the occurrence/dispersion of LLPS in high concentration solutions, such as cytosol.