The 2021 Nobel Prize in Chemistry has recognized the enormous potential of asymmetric organocatalysis as an environmentally benign enabling technology. While the pioneering studies of the field were based on the reversible covalent interaction of the substrate with the catalyst (via enamine or iminium formation), much recent work has focused on organocatalysts that interact with the substrate(s) in a non-covalent manner (e.g. thiourea catalysts). A privileged class of catalysts that operate via non-covalent interaction are chiral BINOL (1,1'-bi-2-naphthol) phosphorus(V) Brønsted acids (Fig. ). Typically, these catalysts activate the substrate by protonating a Brønsted-basic nitrogen atom and subsequently coordinate the activated species by ion-pairing and/or hydrogen bonding, thus guaranteeing stereoselectivity. A notable trend in BINOL-derived phosphoric acid organocatalysis is that they have been endowed with very large aromatic groups in an effort to increase stereoselectivity by generating a confined reaction space. Similarly, two BINOL-moieties have been covalently linked in imidodiphosphates, which exhibit fine-tuned pKa values and highly confined reaction sites whose structural complexity resembles that found in enzyme pockets. In light of this trend toward architectures featuring confined reaction sites, we wondered whether the integration of a phosphoric acid into the cavity of a shape-persistent macrocycle could lead to improved reactivity or selectivity. The cycloparaphenylenes (CPP) seemed particularly suitable for this purpose as they are highly strained and comprise only aromatic units, which makes them exceptionally rigid and susceptible for - interactions. While their optoelectronic and supramolecular properties have led to applications in organic lightemitting diodes (OLEDs), organic field-effect transistors (OFET) and organic photovoltaics (OPV) , their use in synthesis has been restricted to stoichiometric (active) template effects and the non-specific initiation of asymmetry amplification in a Soai reaction. Herein, we report the synthesis and investigation of chiral nanohoop organocatalyst PO4H-[9]CPP. By closing a strained CPP macrocycle around the privileged BINOL phosphoric acid, we create a unique reaction site that exhibits a well-defined cavity as well as ortho-substituents that are bent towards the cavity and conformationally restricted. We chose the asymmetric transfer hydrogenation of quinolines as benchmark reaction to test the new organocatalyst, because pioneering work by Rueping established the beneficial role of large aromatic ortho-substituents on enantioselectivity, which was attributed to a confinement effect (Fig. ). Moreover, Niemeyer and coworkers used this reaction recently to investigate the effect of another complex topology on organocatalysis: in a highly flexible [2]catenane architecture, the interplay of two Brønsted acid sites was found to increase enantioselectivity (Fig. ). We now show that the rigid nanohoop approach, despite offering only one reaction site, leads to much higher enantioselectivity than the conventional BINOL catalyst (with comparable orthosubstituents).