However, despite the positive results obtained through this rather simplistic strategy, it should be underlined that the development of barostat(s) applicable to the case of not periodic boundary conditions would be strongly beneficial to allow a finer tuning and control of the applied pressure, as well as enabling a better generalizability of the model. Another possible approach would be the application of gravity only, which should be enough if simulating explicitly the drying time (typically in the order of minutes at the industrial scale and hours at the lab scale). However, the latter would have been prohibitively expensive by using the computational resources used along this work.