From equation 14, we found a degradation in the precision of Δ𝐺 values with respect to that of 𝒢 (𝑛, 𝑘 𝑓 𝑢𝑙𝑙 ) when testing edge counts linearly related to the number of edges -1𝑛, 1.5𝑛, 2𝑛, and 3𝑛 (Fig. ). Further, we found high and stable relative precision in the predicted changes in free energy for varied 𝑛 at 𝑘 = 𝑛 ln(𝑛) (Fig. ).