Because of their great specificity and affinity for binding to cancer-specific markers, aptamers are perfect for targeting cancer cells with few off-target effects. They are effective and adaptable for both therapeutic and diagnostic applications due to their adaptable structure, which enables precise targeting of distinct cancer cell receptors. These include proteins, molecules, and cells; the aptamer can bind them with high affinity and specificity. SELEX was used to select these synthetic molecules through iterative binding, separation, and amplification rounds . Because aptamers can uniquely fold into 3D shapes, they can interact with the target similarly to antibodies . Due to their chemical modifiability, ease of synthesis, and stability, they are helpful in many applications, such as therapeutic, diagnostic, and research.