Penicillium genomes showed that there were further unrealized possibilities for this species to produce secondary metabolites than anticipated. However, Penicillium fungi have been highly regarded for their pivotal involvement in biotechnological enzyme production. This genus holds significant importance in the creation of crucial industrial products, including penicillin and statins. As highlighted by Chavez et al., penicillin serves as a rich source of enzymes, particularly xylanolytic enzymes. The utilization of xylanases derived from Penicillium sp. has gained increasing prominence in various biotechnological applications. In addition to its exceptional capacity to generate new bioactive secondary metabolites, P. sclerotiorum is also a valuable source of enzymes for biotransformation and biotechnological applications. P. sclerotiorum is the source of a unique and innovative ß-D-glucosidase that hydrolyzes ginsenoside Rg1, as reported by Wei et al. This particular ß-Glucosidase demonstrated the capacity to hydrolyze ginsenoside Rg1 at the C6glucoside site, hence producing the uncommon ginsenoside F1. This ß-D-Glucosidase basically has the potential to be used in large-scale in vitro operations or in conjunction with P.