The central homotetramer and the homoctamer lipid cavities successfully generated thousands of non-toxic fitted-children. Their top-children predicted low nanoMolar affinities, high specificities and similar docking cavities than previously described qac or lipid binding molecules. Some of these topchildren, targeting similar binding cavities that previously demonstrate inhibitors may increase their possibilities to real bindings and perhaps to experimentally interfere with KcsA K + flows. In contrast, lower affinities and therefore much lower expectatives, were predicted by children derived from elongated dga-parents.