The consensus model showed a mean BA of 0.835 considering the cross-validated predictions of the 55 target-associated binary classifiers, with mean precisions for identifying active compounds ranging from 0.923 for those compounds closer to the training set, to 0.810 for those farther from the training set. For the epigenetic target prediction task, mean precisions ranged from 0.952 to 0.773 under the same scheme.