The aforementioned NE-FGR (Eq. 17) can be further simplified via various additional approximations. Most obviously, the rate defined in Eq. 17 is time-dependent, meaning the resulting EOM is not Markovian. To arrive at the more widely used Markovian version of the rate equation, consider the t → ∞ limit of Eq. 17, we have the E-FGR rate constant expression as