Here, an optimal human time based on completing a generative AI task in this study was found to be 25.16x slower than the slowest generative AI response, and 117.56x slower than the fastest GenAI answer shown in Table . 10 recent papers were analyzed using ChatGPT-4o and o1-preview to create fast, high quality, and significant summaries that served as a 6,322 word input to produce solutions to paclitaxel, C 47 H 51 NO 14 , biosynthesis, enzyme engineering, recommendations to new research areas, and addressing challenges to help guide the future of the field. Both speed and quality of answers were primarily a function of effective LLM and LMM software releases in 2024. In specific, the ChatGPT-4o release in May, 3.5 Sonnet release in June, Llama 3.1 405B release in July, and o1-preview release in September have significantly closed the gap between human and artificial intelligence solutions, while also maintaining considerable speed-ups.