obtained with both automatic segmentation and manual measurement (Figure ) give remarkably similar mean particle sizes across batches, as summarized in Table . The average mean particle size from automatic segmentation was 94.0 ± 0.5 nm, which shows very low variation between batches as also illustrated in Figure . The mean particle size from manual measurement of particles was also very similar at 95.3 ± 2.5 nm, confirming the reliability of automatic segmentation. As discussed before, the size values measured from DLS for these samples were larger than the values measured from TEM images, as expected. Altogether, we see a very low variation between batches of below 3% in mean particle sizes from all size distributions.