Magnetic resonance imaging (MRI) is a powerful clinical technique most commonly used to produce structural images of the human body from observation of water and fat molecules, which are easily detectable because of their relatively high concentration. Unfortunately, many interesting biomolecular processes occurring in the body involve metabolites at lower concentrations, which precludes MRI-observation of these biochemical reactions, owing to the inherently low sensitivity of MRI. Recent advances in the field of hyperpolarization-enhanced nuclear magnetic resonance (NMR) have made it possible to produce metabolites with NMR signal enhancements of 10 4 -10 5 1-15 . One example of such a hyperpolarization method is parahydrogen induced polarization (PHIP) in which hydrogen gas enriched in the para spin isomer is chemically reacted with an unsaturated molecule to generate a product with hyperpolarized 1 H nuclear spins . In a second step, the hyperpolarization can be transferred to other nuclei, e.g. C or N . PHIP is renowned for being inexpensive, simple to use, and allows for the production of hyperpolarized substrates with a high repetition cycle.