results from a formal elimination of an equivalent of HF from 3 along with isomerization of the unsaturated bond to the internal position. This species was also formed through a direct reaction of IPrCuO In summary, we have developed a continuous flow process for the production of small chain fluorinated building blocks from trifluoromethane (HFC-23) and 2,3,3,3-tetrafluoropropene (HFO-1234yf). Flow conditions offer significant advantages over batch, including: (i) improved production rates, (ii) better control of exotherms (meaning cryogens can be avoided), and (iii) reductions in the volume of solvent and fluorinated gas required for efficient conversion. Accessing building blocks 2 and 3 on ~10 mmol scale has enabled their further development as reagents to install C1 to C3 fluorinated motifs into organic molecules. These has been achieved through carboncarbon bond formation via the difluoromethylation, trifluoroallylation, and difluoroalkynylation of carbonyl and imine functional groups.