For long-term stability studies, ATV-loaded polymer micelles were stored in Eppendorf tubes containing the precipitate (if any occurred) at ambient conditions (≈ 25 °C) under the exclusion of light. Prior to ATV quantification, all formulations were centrifuged to remove any precipitate, diluted with ACN/H 2 O = 60/40 (v/v) and quantified by HPLC analysis at 245 nm.