Leveraging the capabili�es of 2PLP, PDMS-based microscaffolds can now be 3D printed with higher resolu�on and arbitrary shapes, such as microchannels, microwells as well as other complex geometries. Here we demonstrate that these 3D-printed PDMS-scaffolds can be used to control the nema�c orienta�on in 3D. In order to prove the success of our method, we calculated the expected orienta�on field with Landau de Gennes theory for the given boundary condi�ons and then compared the measured and simulated birefringence of the different samples. The excellent agreement between experiment and theore�cal calcula�on has proven that the level of controlling LC directors is not only limited to the top and botom surfaces, but also extends along the Z-axis. Furthermore. the method was also applied to inves�gate the actua�on of 3D printed LC microstructures with temperature and we observed exactly the deforma�ons predicted with an elas�c theory. This opens the door for 4D