The technique is straight forward and does not require any specialized equipment other than sonicaters and centrifuges. Using sonication and vortexing also ensures good dispersion and encapsulation of Curcumin. However traces of DCM may remain, which could pose toxicity issue to solvents. Excess of PVA may interfere with performance of nanoparticles, hence, should be minimized . Schematic diagram for preparation of curcumin nanoparticle by Single Emulsion Solvent Evaporation is shown in figure .