The studies described herein show that ketene exposure can occur from vaping or dabbing cannabinoid acetates. This is not surprising, considering the fact that ketene was previously shown to form via a structurally-related phenyl acetate-containing compound, vitamin E acetate, under ecigarette vaping conditions. The ketene emission levels observed in the dabbing experiments were in range of the NIOSH IDLH value. More studies are needed to understand the factors promoting ketene formation vaping cannabis and related products, along with in-depth profiling of the contents of cannabis oil condensates, and are underway in our laboratories.