The LC of both, the LC-HRMS and the LC-MS/MS instruments, involved an Agilent 1290 Infinity II UHPLC with the chromatographic parameters previously optimized by Oesterle et al. . The LC-HRMS system consisted of an ESI source and a Sciex ZenoTOF 7600 MS, with the source and MS parameters listed in Table .5. Data was acquired in DDA mode with the 10 most intense ions selected for fragmentation and an MS 2 inclusion list comprised of the combined 3223 entries from PhytoHub and Exposome-Explorer . Conversely, the LC-MS/MS system consisted of an ESI source and a Sciex QTrap 6500+ MS, with the source and MS parameters listed in Table . . Data was acquired in scheduled multiple reaction monitoring mode (MRM) as previously described by Oesterle et al. .