Timescales, τi, and their weights, αi, are typically solved by fitting Eqs. 1-4 to the experimental data or using MD simulations . Notably, transverse spin relaxation time in Eq. 2 is given without chemical exchange contribution, R • 2 = R2 -Rex, where Rex arises from chemical or conformational kinetic processes, where nuclear spins transfer between different chemical environments on microsecond to millisecond time scales, that affect experimental R2 values but are not captured by Eq. 2.