In this study we create a benchmark for large-scale CNC production life cycle assessment, from which different variants could be derived, with respect of variations in design, in operating conditions, location of the plant and energy mix used. To meaningfully embrace the multiplicity of factors affecting the LCA results we undertake a systematic analysis of CNC production, considering key parameters of the manufacturing process, process design as well as geographic location (as this determines energy sources). For this we developed life cycle inventories (LCIs) that can easily be used by other life cycle practitioners in their LCA models of CNC-based applications.