Alzheimer's disease is the leading cause of senile dementia, with over 55 million cases reported by the World Health Organization in 2021 . Even though the cause of Alzheimer's is not completely known, a relation with aggregation and deposition of Amyloid β (Aβ) in neural tissue is widely accepted as a contributing factor on the onset. Transition metal ions and oxidative metabolism have been proposed to play fundamental roles in the process of aggregation and deposition of Aβ in Alzheimer's disease . The binding of divalent metals, such as copper (Cu(II)), iron (Fe(II)) and zinc (Zn(II)), with disordered fibrillogenic proteins, such as Aβ, influences the aggregation process of the protein, contributing directly to the neurotoxicity of the fibrils , and thus, to the severity of the neurodegenerative disease . It has been reported that both the monomeric and oligomeric forms of Aβ are neurotoxic . Interestingly, the concentration of Zn(II) in the brain, which varies from 150 to 200 µM in the neocortex, is one order of magnitude higher than the ion concentration in blood. Furthermore, although Zn(II) concentration stay relatively constant throughout adult life, a significantly elevated concentration has been found in the brains of patients affected by Alzheimer's disease . Therefore, the role Zn(II) plays in Alzheimer's disease has become of great interest.