The D2A-dGsolv-anion uncertainties at first glance seem to match the expected uncertainties of the ∆G * solv (A -) data as detailed previously. However, for comparison to "experimental" data, we must exclude consideration of systematic errors because the same value of ∆G * solv (H + ) is used in both datasets, and we assume that systematic offset in ∆G o acid, gas (AH) is captured in the gas-phase correction term. The remaining non-systematic uncertainties (that is, from the ∆G * solv (AH) calculations, pK a , and relative error in ∆G o acid, gas (AH)) in D2A-dGsolv-anion is approximately 1.6 kcal mol -1 across all solvents. The RMSE values in Figures and are higher in non-aqueous solvents than 1.6 kcal mol -1 , so the actual uncertainties of the non-aqueous data in D2A-dGsolv-anion are higher than expected.