The VFZ is a newly developed tool that allows for efficient and relatively accurate predictions of properties across the 5DOF space by building on the recent GBO distance metric which "correctly determines the angular distances between GBs with a common normal or misorientation" and "closely approximates the geodesic metric on SO(3)×SO(3) for all grain boundary pairs while maintaining the ability to be analytically minimized with respect to the U (1) symmetry" . To best describe what the VFZ framework is and how it all fits together, we summarize its requisite parts and steps for creating and defining a VFZ, mapping GBOs into the VFZ, distance calculations, and interpolation, followed by a brief comparison with the traditional GBO metric (Section S1). A 2-sphere analogue to Voronoi fundamental zone grain boundary octonions (VFZ-GBOs) is provided in Figure . The methods are based on functions and scripts from (github.com/sgbaird-5dof/interp), and we refer the reader to Baird et al. for a detailed description of the methods and model.