PTFE is an alternative binder that can be dispersed in water and exhibits high chemical and mechanical stability as well as strong hydrophobicity. Up to our knowledge, PTFE has not been explored as a binder in COF-based cathode materials for LIBs (Table ) and has only been used in two examples of COFbased anodes without any comparative analysis with PVdF. PTFE-based DAAQ-TFP-COF electrodes were prepared (see ESI for experimental details) to compare their performance with those based on PVdF. We first confirmed that the PTFE-based electrodes were insoluble in all the electrolytes used (Fig. , ESI). In general, all the initial capacities and capacity retentions of DAAQ-TFP-COF electrodes increased when PTFE was used as a binder, regardless of the electrolyte (Figs. S9, S10 and Table , ESI). One of the main reasons for the better electrochemical performance of the PTFE-based electrodes is due to its fibre-like structure, which results in a more porous electrode, as can be observed by comparing the morphology of electrodes based on PVdF or PTFE binders (Fig. ). Such porosity may facilitate the ion diffusion and accessibility to the redox-active sites, as well as allow easier swelling of the polymer electrode. The capacity retention tendency was similar to that obtained with PVdF-based electrodes, with LiTFSI in TEGDME and LiPF 6 in EC/DEC showing the best and worst electrochemical performance, respectively. It is important to highlight that DAAQ-TFP-COF shows a capacity of 147.5 mA g -1 after 100 cycles (99% capacity retention) at a rate of 150 mA g -1 when using LiTFSI in TEGDME as electrolyte and PTFE as a binder (Fig. ). After subtracting the carbon black capacity contribution (Fig. and Table , ESI), the capacity obtained corresponds to the 88% capacity utilisation of the active material at 150 mA g -1 (theoretical capacity = 151 mAh g -1 , see ESI). We note that our results are similar to those of the same active material when exfoliated (DAAQ-ECOF) and using PVdF as a binder (capacity of 145 mA g -1 after 70 cycles at a rate of 20 mA g -1 ). These results suggest that both proper binder selection and the exfoliation of the active material can lead to improved utilisation of redoxactive sites. However, the top-down exfoliation of bulk COFs still presents some challenges such as the difficulty in precisely controlling the thickness of the exfoliated material and the relatively low yield for the synthesis of few-layer COF nanosheets, limiting the homogeneity and scalability of the active material. The use of PTFE binder is a more straightforward approach allowing significantly higher process yields while being both more cost-effective and simpler.