In addition, over half a million marine animal species worldwide offer significant opportunities for drug discovery through genome mining . Yet, the scarcity of highquality genomic sequences for these species poses a major challenge, with fewer than five hundred genomes of low to medium quality available in public databases . This limitation hinders the biosynthesis-guided exploration of natural products derived from marine animals. The collection and sharing of high-quality genomic data on marine animals will be crucial for enabling sustainable chemical research on marine chemodiversity in future studies.