to reduce α-chloro/bromoenoates and α-chloro/bromoenones, with generally high selectivity but modest yields, particularly for aromatic-α,β-unsaturated compounds. Here, a highly flexible novel biocatalytic approach to enantioenriched sp 3 fluorides, via the reduction of α-fluoroenones and αfluoroenoates, is described to provide access to a diverse array of functionalized chiral fluorinated compounds in good to excellent yields and stereoselectivities (Scheme 1d).