Some methods in the challenge achieved a good octanol-water log P prediction accuracy. Figure shows the performance comparison of methods based on accuracy with RMSE and MAE. The uncertainty in the correlation statistics was too high to rank method performance based on correlation, but we provide an overall correlation assessment for all methods in the SI in Figure . submissions achieved a RMSE ≤ 1.0 log P units, but no method achieved a RMSE ≤ 0.5 log P units. Methods that achieved a RMSE ≤ 1.0 log P units were mainly empirical, but some were QM-based. Prediction methods include 15 blind predictions and one reference method.