Table1-2 below present the average overall toxicity values for different X values, considering subsets of 1,000, 2,000, and so on, molecules ranked according to their overall toxicity scores. A comparison of the results in these two tables leads to some surprising conclusions. Despite evaluating over 300,000 natural products, the average overall toxicity score is only slightly higher than that of approximately 3,000 approved drugs, all of which have undergone rigorous and costly multi-phase safety trials.