We focus on the AB4 T-4 E-mode space as it provides the simplest example of a configuration space where discrete orientation permutations are "stereoisomerically connected" (there are feasible polytopal rearrangements connecting the orientation permutations). The AB4 T-4 E-mode space is a subspace of the full AB4 T-4 (E × T2)-mode space -a far more complex 5-dimensional space.[ref]