Of the 98 predicted targets, a total of 11 drug-target interactions were experimentally validated based on the availability of fee-based in vitro testing services (Table ). Among predicted targets, two members of the Transient Receptor Potential superfamily of calcium channels were suggested, namely short transient receptor potential channels 6 (TRPC6) and 3 (TRPC3). Commercial assays were unavailable for TRPC6 or TRPC3, and therefore, these targets could not be validated. Instead, transient receptor potential cation channel subfamily M member 6 (TRPM6) was employed for the respective binding assays.