Desiccators are made of glass or plastic. In contrast to plastic desiccators, those made of glass are most often suitable for vacuum operations but more expensive than their plastic pendants. Since glass desiccators are made of thick walled glass they are heavy and breakable. Therefore, careful handling is crucial. The airtight sealing is achieved using a suitable grease on the flat ground joint. The lid has to be slid on and off the ground joint of the base to prevent damage.