α1 antitrypsin is the most commoninhibitor of coagulation and regulates enzymes involved in inflammation, particularly neutrophil elastase . Similarly, α2 macroglobulin is a broad-spectrum protease inhibitor that inhibits the activity of proteases belonging to diverse catalytic classes . Analogous to the previously studied magnetic nanoparticles with PMβCD:MPC ratios (1:3) and (0:4), the present systems adsorbed moderate amounts of α1