The correla ve confocal reflec on images in Figure (right, grey scale) and their corresponding reflec on coefficients (grey line, Figure le ) reveal that once again, from 1 min onwards, the films again exhibit significant confocal reflec on, consistent with nano-and micro-scale phase separa on, that evolves within the films over me. Again, the reflec on 'wave' in the gel phase gradually progresses deeper into the gelphase of the film, albeit more slowly than for the 20% drug loading, with its onset posi on appearing in the gel phase at approximately -49 µm, -63 µm and -91 µm at 1, 2 and 5 min, respec vely. This onset trails behind the glass-gel interface by about 19 µm and 27 µm, at 1 and 2 min, respec vely (also see Figure , in the Suppor ng Informa on).