The other result from Table is that all endo-N cages are more stable than the endo-C cages because of lower energies. The lower energy means it is closer to the ground state energy. The more H-bond existing on the endo-N cage may yield a better result of encapsulation, and the more vital interaction between host and guest can improve the more robust complex, which can contribute to drug delivery to a target. Consequently, endo-n metallacages should be prioritised over and-C cages for cisplatin encapsulation.