Synthetic liposomes represent the lipid bilayer backbone of biological membranes. Of particular, anionic liposomes with a size of around 100 nm have been used as models of extracellular vesicles, ranging in diameter from 50 to 150 nm, that are cell-secreting products playing crucial roles in intercellular communication by carrying cargo such as miRNA and proteins. With increasing their attraction as a biomarker for diagnosing and prognosing serious diseases, small anionic liposomes have been utilized as an easy handling structure mimicking extracellular vesicles for understanding their functions in biological phenomena. In addition, these synthetic liposomes and extracellular vesicles have attracted much attention as useful careers of a diversity of cargos ranged from small molecules to large biomolecules for the construction of drug delivery systems. Meanwhile, solid nano-and meso-porous materials hold great premise as platforms for integration of various molecules including proteins , nucleic acids and small molecules. The immobilization and controlled release of these molecules were achieved on the solid porous materials, which paves the way for the development of separation techniques, biosensors containers, and drug delivery systems. This class of solid porous materials is thus expected to be compatible with liposomes and extracellular vesicles with a view toward the above applications. However, little work has been done in this direction whereas there are some reports on hydrogels and nanofibers , in which intact liposomes were released from hydrogels spontaneously and from nanofibers by dissolving polymers constituting the nanofibers.