The properties of a two-electrode system can be predicted by analyzing the three-electrode IRcompensated cyclic voltammetry versus a common reference electrode of each half -cell with the other. In a two-electrode electrochemical cell, the current passed through the anode and cathode are equal. The operating potential of the electrochemical cell in this configuration is the potential at which the current passed through the anode matches that of the cathode. If the anode and cathode areas are the same, it is equivalent to match the current densities to find an operating current density, jop. The graphical representation of this procedure is shown in Figure . The required applied potential (Vop) can be determined for a given operational current (Iop) using a LLA procedure. The potential predictions of a LLA account for the potentials of each electrochemical reaction, disregarding any potential requirements from other elements of the electrochemical system. A bipolar membrane has a corresponding turn-on bias which needs to be accounted for in a LLA. In addition, the load-line analysis is based on sweeping voltametric measurements, which are dynamic methods to study the system and long-term effects, such as ion depletion close to the catalyst surface and the resulting concentration polarization. LLA does not account for the solution and BPM electrochemical resistance or the non-faradic potential losses unless they are included in the effective circuit of analysis. A more accurate prediction of the operating point would include these details, though they are sensitive to the details of a specific cell assembly, including the relative electrode placement, orientation, and membrane size. The benefit of a LLA is to approximate what operating characteristics are achievable for a cell based on an anode and cathode pair with the measured electrocatalytic properties. Hence, it provides an upper bound on the performance in the absence of further limitations that can be ascribed to the design of a particular system construction.