Sequence motifs. We searched for sequence motifs using the website MEME Suite specifically with the Multiple Em for Motif Elicitation (MEME) tool (v.5.1.1) , which allows us to find recurring patterns or motifs without gaps within the sequences. We summarized the parameters used in the search in Table . We used MEME classic mode and the protein standard alphabet for motif discovery, where we introduced a set of sequences and the tool identified enriched motifs. For the site distribution, we selected the option zero or one occurrence per sequence (zoops), where MEME assumes that each sequence can contain at most one occurrence of every motif. We chose ten motifs per search; the tool continued to search until ten motifs were found or one of the other thresholds (i.e., the maximum execution time) was reached. Finally, we left the advanced default options.