As such, seeding simulations can be performed using any MD engine that can handle the force field. Typically, for a solute concentration, one performs at least five simulation campaigns for different values of 𝑛 0 (where each seed is carefully relaxed in the solution), each of which involves running a handful of independent simulations to obtain the mean trajectory that indicates the relative stability of the cluster. Seeding methods can, therefore, be relatively cheap and easy to perform in systems where the attachment of monomers from the solution to crystal occurs readily over simulation timescales.