PocketMatch output 16,152,318 pocket comparisons, only 1603 of them were above 0.6. After the removal of chains that don't belong to COVID-19 (these chains belong to the ACE2 receptor), it resulted in an 860 comparison pair, which contains 184 approved drugs, they contain antivirals, antimicrobial and anticancer to name a few. From table (1) it's more rational to choose the 0.7 cut off as it's more strict, but the total number of drugs on that cut off is only 11 drugs, and by choosing 0.6 we would explore more drug space.