Following this, we then present the pipeline for how one could obtain an MFEP from an FEL without any prior guess. The first step is to implement the shifted k-means algorithm to locate the positions of the energy minima. Two inputs are required, which are the shift m and the number of reactants n. The shift m discards every point that has a free energy F(q) that is larger than m, so that only the most stable points are clustered with a weight of F(q) n , in which n > 0 if F(q) < 0 and vice versa.