A new graphical program to perform non-linear regression with focus on the calculation of stability constants by means of NMR titration and ITC experiments has been presented. The software is written in C++, using the Qt Toolkit and the Eigen library and is fully open source and therefore transparent regarding the underlying mathematics and algorithms. Additionally to the pure estimation of the various physical parameters, that are used to describe the complexation process, statistical analysis can be performed to obtain confidence intervals for each single parameter and to gain a deeper insight in the performed experiments. The adoption of several techniques are reported, which are already described in the literature (Monte Carlo simulation and F-Test approaches), however the routinely usage of these approaches has not been reported yet. We hope, that SupraFit provides a good basis to analyse titration experiments with respect to the statistical judgement and to further improve the insight in the supramolecular systems. We additionally aim to provide SupraFit as easyas-necessary and as powerfull-as-possible regarding the usability of the user interface, that all the tools brought by SupraFit are straightforwardly accessible. Contributions like new models or statistical post-processing are welcome.