Catalysis through Nickel designed composite materials has grown exponentially for considerable applications in the past few decades. As it has a strong affinity for cobalt, copper, and many other transition metals. Thus, present to it real sophisticated advantages in various technological fields. Research for discovering highly active, selective and stable catalysts has been carefully regarded for material engineering for many energy fields and other applications using both simulation and experimental methods . for exemple, these reactions, oxygen reduction (ORR), oxygen evolution (OER) and both Hydrogen oxidation (HOR)/reduction (HRR) so well studied in recent years through diverse form of materials as fully shown in this research articles . Also, many forms of designed catalysts have been considered for catalytic conversion of harmless (CO2) and harmful (CO) to high-value-added chemicals and fuels in order to decrease the use of fossil fuels and as well as limit the impact of toxic gases in our environment . Moreover, the electrochemical conversion of alcohol fuels such as methanol (C1), ethanol/ethylene glycol (C2), glycerol/propanol (C3), and other fuels, have been extensively studied for fuel cell applications, utilizing unlisted materials which include supported , core-shell, unsupported metallic nanoparticles, metal oxides, and as well as metal oxyhydroxides as described in these research papers . Many kinds of composite materials have been engineered for the catalytic decomposition of organic compounds through hydrolysis reaction, as the case of ammonia borane (AB), amine borane, for green hydrogen generation. These designed materials could be based on transition metals nanoparticles in unit with diverse form of supporting materials . Both catalytic hydrogenation of (CO/CO2/Olefins) and ultra-deep desulfurization of transportation fuels have been widely discussed through diverse ways with the aid of designed catalytic composite materials, which present high yield of hydrocarbons generation and suitable sulfur removal from gasoline fuels, as evidenced in this papers . these are an important issues as they contribute to limit the percentage of greenhouse gases in our environment, which is beneficial for mankind. In order to avoid or limit the utilization of fossil fuels, recently, many researchers have proposed more strategies to produce clean fuels such as hydrogen (H2), Ammonia (NH3), hydrous hydrazine, Metal-ion batteries from diverse sources using nanosized materials. In this ways, more recently, Naseeb, W et al have engineered Ru-CoO heterostructures nanoparticles anchored over dual heteroatom (N,S) co-doped graphene nanosheets named as (Ru-CoO@SNG) for high catalytic hydrogen production from water electrolysis by direct hydrogen evolution reaction (HER). In 1.0 M KOH, Ru-CoO@SNG displayed -90 mV and -10 mA as overpotential and current density under HER process which was comparable to the state-of-the-art (Pt/C (-60 mV)) a long with stability. Also, Singh,S et al showed the generation of hydrogen via the catalytic decomposition of hydrous hydrazine (H2NNH2* H2O) over a bimetallic Nickel-Iridium (NixIr1-x-B) catalysts. As resulted from the experimental studies, Ni0.95Ir0.05-B and Ni0.90Ir0.10-B exhibited the highest selectivity for hydrogen release from hydrous hydrazine. Which was close to 100% of hydrogen selectivity from H2NNH2* H2O decomposition. Moreover, Both (Ni1-x-Ptx) and (Ni1-xPdx) have been considered as a good catalyst materials for the degradation of hydrous hydrazine as fully described in . Suitable selectivity (close to 100%) was achieved with Pt content as low as 7 mol % and superior to 80% hydrogen selectivity with 40% of Palladium loading respectively. These Ni-M (M = noble metals) revealed to be excellent hydrazine conversion catalysts for H2 release, but their cost and Poisoning by harmful spices hindered their application. This is why the search of new routes are on the way of scientific research fields. So, in this sense, Noble-metal-free bimetallic nanoparticles especially Ni-Fe alloy catalysts have displayed excellent catalytic feature for complete degradation of hydrous hydrazine, the Ni-Fe alloy with equimolar composition exhibited the highest selectivity (100%) of hydrogen production in 0.5 M of sodium hydroxide at 343 K as reported by the above Author . A mini-review paper has been established by Rai,R et al which demonstrated the alternative use of the activated bimetallic nanostructures catalysts for specific C-C coupling reactions. So, which means that bimetallic alloys in diverse forms can be applied in many fields of chemical engineering reactions. Hence, more recently, it is reported the application of bimetallic Ni4Cu1 supported over poly-phenylenediamine (Ni4Cu1/PpPD) as potential candidate catalyst for efficient conversion of alcohol especially ethanol oxidation reaction (EOR) in alkaline media as shown in Chemchoub's research article . (Ni4Cu1/PpPD) catalytic features were anodic current density and the onset potential which was as high as 70.5 mA/cm 2 and 0.39 V respectively. In 2013, reviewed the advances on bimetallic Ni-based catalysts NPs synthesis, design and characterization for the steam reforming. Alloying Ni with both noble and non noble metals are discussed. It is noticed that the effect of the second metal will improved the performance Nickel based catalyst materials, it will subsequently increase the reactivity and avoid the deactivation of the designed Ni-based catalyst under the studied catalytic reactions. therefore, the strong affinity of Ni to cobalt, copper,zinc, and many other transition metals. Thus, award to it very sophisticated advantages in various technological applications. Hence, in this paper, we focus on the recent advances on nickel-based multifunctional