simple virtual active score recovery rates (Figure ). Within the first 10% of the DOCK D4 library, RAD recovered 91% of the top clusters and 92% of the top scaffolds. For AmpC, RAD recovered 92% of clusters and 93% of scaffolds. The null traversal only recovered 50% and 48%, and 49% and 51% of the D4 and AmpC clusters and scaffolds. These trends were also borne out with Glide (Supplementary Table ).