Other bioactive compounds isolated from the marine fungus A. versicolor were compounds 41-42, 47-48, and 50-54 . 1-methyl emodin which is an O-methylated derivative of emodin and both were isolated from A. versicolor , exhibited better cytotoxic activity than emodin itself against human epidermoid carcinoma cell line (KBv200) with an IC50 value of 190.81 μM , although 41 did not show any cytotoxicity against the human leukemia cell line (CCRF-CEM) and some other solid tumors (human lung H-125, human colon HCT-116, human liver Hep-G2) . On the other hand, 41 showed less inhibitory activity against Hepatitis C virus (HCV) protease than its parent 13 with IC50 values of 40.2 and 22.5 μg/mL, respectively . The same study showed that the new metabolite from A.