Compared with M MMT PEI -M MMT nanocomposites (2,4,6,8,10 & 40 %), CS-M MMT S-M MMT, β-CD-M MMT nanocomposites and L-M MMT composites, the hybrid MNP NCs were designed as CS-MNP, CM-β-CD-MNP and compared with their EE % & PLE %age of chlorpyrifos. Finally, spectrophotometrically, sustained pesticide release (SPR) was determined wherein time-dependent release of chlorpyrifos from the above synthesized formulations was compared. (Figure ). Because of its phenol groups, which are capable of scavenging free radicals, Lignin was tried as it can serve as a stabilizer against UV degradation or thermo-oxidation (Figure ). Although the macro-to-nano-particles were discussed in a significant number of papers, it was shown that particle size reduction to nano shows pronounced E.E and SPR values due to more spaces (surface area) for insecticide molecules to be trapped. Another main aim of this research is to figure out which is the better nanotechnology (MNP vs M MMT). This is the first systematic relative account of E.E %, PLE wt % and polysaccharides vs. lignin vs. PEI aqueous release activity of chlorpyrifos using M MMT/MNP nanomaterials. Dialyzer tubes (MWCO 1KDa) were procured from G-Biosciences. Carboxymethyl-βcyclodextrin was synthesized from microcrystalline β-cyclodextrin as per literature procedure 36 2.2 Analytical methods. X-ray Diffraction (XRD) was performed using Bruker D-8 advanced diffractometer in the 2θ range of 10 to 90 °C. The average crystallite size with and without surface coating was estimated using the Scherrer equation. Fourier transform infrared (FT-IR) spectra were recorded on Agilent Cary 660 spectrometer using the KBr pellet technique in a range of 4000-400 cm -1 . Thermogravimetric analysis (TGA) was performed to determine the degradation/decomposition behavior of samples using thermogravimetric (TG) analyzer-(Perkin Elmer STA 8000) at a N2 flow rate of 10 mL/min and heating rate of 10 °C/min. Atomic Force Microscopy (AFM) images were acquired using Bruker Multimode 8 and sample analysis was done in tapping mode. The samples were deposited on silicon wafers and analysis was performed at different sections at room temperature and ambient atmosphere.