Understanding and controlling the chemical degradation of liquid electrolytes is key to enhancing the durability of lithium-ion batteries (LIBs). Even inside its electrochemical stability window, the electrolyte can reduce near the anode during charging. This initiates a cascade of reactions and culminates in the irreversible growth of a passivation layer, the solid electrolyte interphase (SEI). This layer is composed of various inorganic and organic species 2 that contain lithium. The resulting capacity loss can be 10% in the first charge-discharge cycle and increases throughout the battery's lifetime. The SEI is electronically insulating but ionically conducting and protects the electrolyte from further degradation while allowing lithium transport. The properties of the SEI and the overall battery performance depend on the initial electrolyte composition and its reactions near the anode. Successful simulations of SEI growth must provide a link between the molecular processes and the emergence of a microscopic structure. In this context, they can play a vital role in the in silico design of electrolytes for use in next-generation high performance LIBs.