The main focus of this paper was to investigate the effect of combined reinforcement learning for pharmacokinetics and potency and the trade-off between them. However, there are other important criteria in hit identification, including the synthesizability of a drug, which were not taken into account here. Some generated molecules displayed unstable or reactive properties that would be infeasible to synthesize. For future applications of this pipeline, it is important to take synthesizability into account as well through measures such as the Synthetic Accessibility score, Retrosynthetic Accessibility score 55 or LED3 score.