Table . Summary of four hydrogels' gelation time. The gelation time of hydrogels is summarized in the Table . The weight percent of hydrogel precursors used is from 1% to 4%. The gelation time is from ∞ (no gelation)to ≤1 second (ultrafast). 2% Dex-Mal and 2% HA-SH is the only feasible formular because longer or shorter time could lead to the failure of biomedical application like cell encapsulation. For example, longer time means lower weight percent hydrogel precursors used, that could form amorphous gel. On the contrary, shorter time could result that the maleimide and thiol groups are not reacted completely, which impacts the cell growth. Consequently, this formular was used for the remaining experiments and analysis. The weight loss of the hydrogels was plotted in figure . It exhibited that weight loss speed of hydrogels. The weight loss of hydrogels reached 18%, 39% and 55% on the first day, third and fifth day respectively. Moreover, on the 7th day hydrogels were degraded around 80% and on nineth day were degraded completely. The swelling analysis is exhibited in Figure . The weights of freeze-dried hydrogels samples are from 1 gram to 5 grams. Since different hydrogel samples will show different swelling ratios. All samples with different weights have similar swelling ratio, which is around 50%. The more hydrophilic samples will be submerged in PBS, the more water will be absorbed, and higher swelling ratio will be calculated. Here, it's clear that the 2% Dex-Mal & 2% HA_SH hydrogels could absorb the water, which has the half mount weight as freeze-dried hydrogels. It indicates the hydrogels created by this formular have good flexibility ability to mimic extracellular matrix. G′ and G′′ were plotted in figure as a function of angular frequency for hydrogels. The hydrogels showed characteristic viscoelastic behaviors. The moduli G′ was always higher than G′′ illustrating hydrogels formed by maleimide-thiol coupling chemistry are elastic solid.