The result reproducibility was assessed by comparing data collected from ten independently prepared electrochemical sensors. The standard deviation (RSD) value of 8.9% (Fig. ) is within acceptable range, according to the Association of Official Analytical Chemists (AOAC) guidelines (International, 1993) and confirmed the reproducibility of the proposed diagnostic approach, from the biosensor fabrication to the signal measurement. The storage stability of the biosensor was thereafter investigated comparing three conditions selected because they are normally implemented in commercial manufacturing storage settings: i) desiccator at room temperature ( RT, 20 ± 2 °C) , ii) humid box at RT, iii) freezer at -20°C. As shown in Fig. , the biosensor maintained its performance at over 80% in the first 4 weeks under all storage conditions and, when kept in the freezer, the activity reached 86.3 % even after 8 weeks (Fig ). These results demonstrate the superior storage stability of our device over the conventional diagnostic platforms and suggests its suitability for real-world applications characterized by challenging conditions. Subsequently, the performance of our biosensor was compared to other devices designed for CRP quantification (Table ). While its sensitivity is lower than that of some previously proposed systems, the LOD is still sufficient to detect CRP in the biologically relevant range spanning from ng mL -1 to μg mL -1 . Remarkably, our device is inexpensive (less than 0.2 € per single biosensor, see Table for details) , rapid (complete analysis within 15 min) and portable. This makes it faster and more cost-effective than both ELISA and other electrochemical anti-CRP platforms, most of which require between 1 h and 5 h. a It should be noted that the results were investigated using the same samples as those reported in ; therefore, we employed the same standard ELISA values.