Figure displays the GM structures of Pt10 and Pt5Ge5 deposited on the rest of the 2D supports, viz., 5-8-5-DV, gr-B, silicene, germanene, 2H-MoS2 and SmSI. Overall, the cluster morphology has a strong dependence on the support. On defected graphene (5-8-5-DV and gr-B) the interaction with the support is not very strong and Pt10 remains globular. Although the vacancy and B dopant serve as an anchoring site, Pt10 still displays quite low Eads (Figure ) due to the inertness of graphene. Ge alloying reduces even more the stability (Figure ) due to a Ge-support repulsion. Pt5Ge5/gr-B is the worst scenario where the Eads, although still negative, drops to -1.81 eV. Thus, on these graphene-based surfaces both monometallic and bimetallic clusters exhibit a globular shape, maximizing the intracluster bonding to the detriment of the weaker cluster-support interaction. The case of Pt10/2H-MoS2 is more favourable, where the adsorption energy to the support increases up to Eads = -7.90 eV. The stronger interaction is also reflected on the cluster shape. Pt10 no longer adopts a globular geometry, but instead it grows in a layered structure, where the Pt atoms are arranged on two different layers. This is in agreement with previous works that report Pt clusters growing with the (111) orientation on 2H-MoS2. In Pt5Ge5/2H-MoS2 however, Ge avoids interacting with the surface. As a consequence, the cluster adopts a 3D structure again to maximize the intracluster bonding and the adsorption energy is significantly reduced as compared to pure Pt. For this reason, PtGe mixing is not as effective as in gas-phase. Strikingly, silicene and germanene show quite different behaviour. On Silicene, Pt10 becomes completely planar with a triangular shape that allows the cluster to completely wet the surface. The silicene support is slightly deformed. In germanene the interaction is even stronger. The Pt atoms "enter" inside the surface and form a "pocket-like" structure. This resembles the strong metalsupport interaction (SMSI) reported for metal-oxides. Unfortunately, a very strong deformation of the support may cause a negative effect since it can compromise its structural integrity, mechanical properties or conductivity. The degree of this deformation may be reduced by growing this 2D support over another stabilizing matrix. The Eads increases spectacularly up to -22.08 eV for Pt10/silicene and -26.13 eV for Pt10/germanene. Regarding Pt5Ge5, Ge shows more affinity with both silicene and germanene and, for the first time, Ge-support bonds are formed. In fact, the bimetallic cluster adopts a quite planar geometry on these 2D materials and the mixing between Pt and Ge is excellent, as found in freestanding clusters. Although the interaction to the surface is weaker than in pure Pt, the Eads values are still remarkably large (ca. 10 eV), suggesting that silicene and germanene could be used to hold PtGe catalysts.