In the following, we describe the construction of a validated, atom mapped database of balanced enzymatic reactions from BRENDA entries. We then describe the details of the models trained for retrosynthesis, forward predictions and regioselectivity prediction. The code to reproduce all processing steps from a raw BRENDA entry to a validated, mapped reaction is available as easy-to-use Python package at github.com/hesther/enzymemap, along with the full dataset via Zenodo at doi.org/10.5281/zenodo.7841780 (raw unmapped and processed mapped reactions). The En-zymeMap Python package amounts to nearly 4000 lines of code introducing currently missing functionality for mapping reactions via reaction rules, correcting wrong reactions, and standardizing atom mappings, amongst many other functions. We note that for some reactions or enzyme classes BRENDA includes additional (uncurated) information not included in EnzymeMap. If one is searching for more information on a particular reaction or enzyme class such as reaction conditions, we suggest the reader check the corresponding BRENDA entry and the original literature sources.