The search space of potential target molecules in this campaign is defined by enumerating all products of a double Suzuki-Miyaura coupling between the MIDA ester (MIDA = N-methlyiminodiacetic acid) of (E)-2-(4-(N-Carbazoly)phenyl)-vinyl-1-boronic acid and 38 commercially available dihalides. A detailed synthesis scheme can be found in Figure . This space is navigated by Atlas using a gaussian process surrogate model with a Tanimoto similarity kernel function. Initial recommendations were generated by training the optimizer on two data points from the original work.