However, in literature some the exposed correlations have already been reported. Phthalate exposure was associated with altered carnitine levels and changes in metabolites associated with amino acid metabolism in the urine of Chinese men ). In our study, carnitine, propionyl carnitine and several amino acids were also correlated with mono butyl phthalate. Pathway analysis was performed for significantly correlated metabolites with mono butyl phthalate (Figure ). The results revealed a potentially strong impact on the alanine, aspartate and glutamate metabolism, the arginine biosynthesis, and the citrate cycle. The pathway analysis of ethyl paraben-associated metabolites exposed similar results, with arginine biosynthesis and alanine, aspartate and glutamate metabolism being the most impacted pathways (Figure ). These two pathways were also the most affected among with benzophenone-1 correlated metabolites (Figure ). The xenobiotics benzophenone-1, mono butyl phthalate and ethylparaben had at least a moderate correlation (correlation coefficient between 0.5 and 0.64) among each other therefore the disturbance in amino acid metabolism might not be triggered by a single compound but rather by a mixture of different chemicals. Further investigations are needed to support our preliminary observations.