where V represents the potential energy term coming from the bond stretching (𝑉 𝑠𝑡𝑟 ), bending (𝑉 𝑏𝑒𝑛𝑑 ), torsional energy (𝑉 𝑡𝑜𝑟 ), van der Waals energy (𝑉 𝑣𝑑𝑊 ), electrostatic energy (𝑉 𝐸𝑆 ), and cross terms (𝑉 𝑐𝑟𝑜𝑠𝑠 ). With the separation of the van der Waals interaction and electrostatic interaction terms in the above equation, the constant parameters of the remaining interaction in the force field could be generated in such a way that the parameters become more transferrable over the whole molecule in comparison to the spectroscopic force field.