Where the reactants, agents, and products are separated by '>' and the individual non-covalently bound species represented by a '.' according to the Daylight SMILES specification. The definition of reactant and agent is ambiguous, as agents may participate in the reaction and contribute mass to the products. Additionally, as the templates are extracted based on atom-mapping, only the species contributing to the product or changing during the reaction were considered in the process. Thus, we have moved all agents into the reactants to give a reaction SMILES of the form: