In our study, we identified two trends associated with countries. The first trend is functionalizing systems with peptides to deliver nanoparticles to reduce the toxic load outside the target tissues (USA, China). The second one is nanoparticles' production with new properties using green synthesis technologies and research in nanoecotoxicology (India, China). Considering the effect of several citation centers demonstrated in Figure (one of which is associated with the USA and the other with India and Asian countries), it is worthwhile to assume that both directions will develop in parallel in the future. Our results on the development of nanoecotoxicological studies coincide with the need to determine nanomaterials' environmental fate, predicted more than ten years ago by Alexis D. Ostrowski et al. .