This in silico analysis demonstrates the promising antifungal potential of 6-gingerol against Candida albicans, highlighting its favorable interactions with key fungal proteins and acceptable pharmacokinetic properties. Molecular docking studies revealed strong binding affinities, particularly with Sterol 14-alpha demethylase and N-myristoyltransferase, suggesting 6-gingerol's capability to inhibit fungal growth and virulence. The ADMET analysis supports 6-gingerol's safety and drug-likeness, though its low absorption and potential immunotoxicity warrant further investigation. These findings underline the potential of 6-gingerol as a natural antifungal agent, paving the way for experimental validation through in vitro and in vivo studies. Further research is recommended to confirm its efficacy, optimize its pharmacological profile, and assess its clinical applicability.