After understanding the nature of the receptor surface, the next step was to perform molecular docking simulations using the HDOCK2.4 software to understand the receptorantibody binding interactions. Figure shows the 3D structure of all the receptor-bound antibodies. Interestingly, most antibodies bind to the drug/ligand binding site predicted by the GrASP web server, as shown in Figure . This further validates our understating of the binding site located on the receptor surface. To choose the optimal antibodies, the following things were considered: The binding site of the antibody must have been the one predicted by the graph neural; (2) The receptor binding energy; and (3) The hydrogen bonds formed between receptorantibodies complexes. Further findings proved that ten of the fifteen antibodies bonded to the druggable site anticipated by the GrASP web server. These 10 antibodies are as follows 1A5F, 1B4J, 1F8T, 1IL1, 1LK3, 2UYL, 2VXS, 2XQB, 3D85, and 4A6Y.