Ensuring a high contribution of the bio-based molecules in the overall chemical supply chains, requires finding of optimal locations, hence strategic molecules, in the network structure. A molecule may classify as a strategic molecule if it shows to be preferably linked in the network. The linkage might lead to shorter synthesis paths, to commonly used bulk molecules, or scaffolds suitable to connect different regions of chemistry. We wish to describe the characteristics of strategic molecules by their linkage in a graph theoretical framework.