As a final study, we will investigate the keto-enol tautomerization of salicylaldimine. This system allows us to test how the TD-ADGA framework fares when applied to a chemical problem with many modes and complex dynamics. In the tautomerization, a hydrogen is transferred between a nitrogen and an oxygen atom to form either the keto or enol form of salicylaldimine. We will in this subsection study the ability of the TD-ADGA to describe the reaction as salicylaldimine reacts from the enol to the keto form. The following description of the setup of the TD-ADGA calculation (excluding the construction of the full reference potential) outlines how the TD-ADGA can be applied to other chemical systems and reactions.