Even over 30-fold macromixing rates were seen in simulations of the 22 m 3 reactor by using more than four feeds, but the additional rate enhancements were not substantial beyond four points. The maximal number of feed points was then settled at four for the following simulations, as using more could complicate practical implementation of equipment with only nominally improved rates. Placing the feeds at the same heights as the impellers was also simulated, but this feed placement led to synchronization of the impeller-wise circulation flows and lowered the mixing rates. Experience and previous research has shown that asynchronous circulation is preferable to synchronous.