These findings are supported by DSC heating/cooling runs shown in Figure . For bulk C30d, two peaks are observed in the heat capacity upon heating and cooling, corresponding to the crystal-rotator and rotator-liquid transitions at lower and higher temperature, respectively. Inside DMPC membranes, the crystal-to-rotator transition temperature of C30d upon heating is decreased by only 0.4 • C, while the rotator-toliquid transition temperature is hardly affected at all. The transition peaks become more narrow and an additional peak is visible at 57.8 • C, prior to the original crystal-to-rotator transition. Upon cooling, the shift in the phase transitions upon mixing with DMPC is more evident: the liquid-to-rotator transition is lowered by approx. 1 • C, and the rotator-to-crystal transition by 1.5-2.0 • C. Small features remain visible close to the bulk transition temperatures. Regarding the properties of the DMPC membranes, the main transition is broadened and shifted to higher temperatures upon addition of C30d, and the pretransition can no longer be observed in the mixture. Notably, the DSC results show no indication of a broad transition in the 45-55 • C interval, proving that no crystallization occurs in this temperature range.