Fig. shows a strong correlation (R 2 = 0.73) between the calculated methods (PerMM and COSMOperm) and BLM / liposomes (abbreviated "BLM"). The BLM method is a very important experimental method because, in contrast to other experimental methods, the BLM is the diffusionunlimited method. Thus, molecular permeability is easily determined using BLM. The BLM is not widespread, and therefore, we do not have as much data available as the PAMPA method.