Injectable polymers are categorized into different types depending on their properties. They encompass hydrogels, non-hydrogels and the hybrids; which are combining properties of different components. On one side, hydrogels with their ability to absorb high water content, mimic the cell environment and are mostly used in the applications as drug delivery . However, they may lack the mechanical strength required for the load bearing trabecular bone defect and find it difficult to maintain the shape in defect cavity . On the other hand, non-hydrogel elastomers have good mechanical strength and mimic the behavior of load bearing trabecular bone. They provide good conformability to the defect site and some of their degradation rate allows them to be replaced by newly formed bone . However, some synthetic materials need to be designed carefully to fulfill biocompatibility concerns. Therefore, a promising approach is to construct hybrid materials that combine the diverse characteristics of the individual components and exhibit tailor-made properties. Moreover, they can also make a 3D structure, known as scaffold, to facilitate bone regeneration by giving a template on which bone tissue can grow .