1 ALK, Anaplastic lymphoma kinase; TRKA-C, Tropomyosin receptor kinase A, B, C; mTor, mammalian target of rapamycin; CDK, Cyclin-dependent Kinase; JAK2, Janus kinase 2; FLT3, fms like tyrosine kinase 3; NSCLC, Non-small cell lung carcinoma; HIV, human immunodeficiency virus. products or derivatives (Figure ). For the purposes of extracting lessons about the design of synthetic MCs, we focus here on the nucleotide site binders.