he key messge of this study is tht reproduile wyp synthesis n e tremendously hllengingF he numer of phseEpure smples rnges from I to Q @if dgxEPPR is onsidered suess when gxEPPR is trgetedA pigF R nd the verge phse frtion of the trget phse is SH7 t mostF ine the seprtion of relted polymorphs is hllengingD the phse mixtures would e unsuitle for most prtil purposesF hile we hve foussed on the di'erene etween syntheses rried out in di'erent lsD irreproduiility issues within the sme l re lso notedF o lthough the )t struturl energy lndspe of wyps is ene(il"y llowing ess to lrge numer of strutures nd properties"the downside n e syntheti di0ultiesF 63 etD if syntheti ontrol n e otinedD preise tuning of his ould not only sve timeD ut lso shed light on ftors onduive to syntheti reE produiilityF etD further insight into wyp synthesis is still required to fully enle the potentil of this promising lss of mterils to e relisedF here re no on)its to delreF