The final conformational FES explored here is that of Molecule XXXII, a target from the 7th CSP Blind Test . As a highly flexible drug-like molecule with a conformation space defined by 11 torsions (shown inset in Figure ), it is chosen here to test the limits of our method. To facilitate comparison with results collected for alanine dipeptide and sulfadiazine, the results presented here were generated using consistent simulation and analysis parameters. Using 50,000 data points in this high dimensional space results in an average data density of approximately 8×10 -5 configurations per rad . Despite the extremely low data density, which is inherently linked to the complexity of the conformational space, we show that meaningful results are achievable. Figure shows the projected 11-dimensional perpoint FES, with cluster centers corresponding to 11dimensional coordinates presented in Tab. II. When comparing this FES to sulfadiazine's in Figure , the features of XXXII can be seen reflected in its own FES. The relative lack of symmetrical torsions results in a less symmetrical FES, and the higher-dimensional FES is much sparser, illustrating that the computational savings arise from a more efficient, rather than more exhaustive, sampling of conformational space.