Herein and as a part of our continuous program on pharmacologically active fungal natural products , we are presenting an extensive coverage over the period 2000-2020 for 208 anthraquinones and their derivatives, extensively reported from different marine-derived fungal genera such as Nigrospora, Aspergillus, Penicillium, Stemphylium, Alternaria, Eurotium, Trichoderma, Halorosellinia, and Fusarium. In addition, we reported here their different biological activities wherever applicable, in addition to a general overview of their proposed biogenesis pathways.