Reaction engineering is crucial in designing highly integrated and efficient processes for optimal utilization of weight, resources and time. The unique challenges of extra-terrestrial sites like Mars or permanent space stations equally pose unique opportunities to reevaluate reaction engineering of already well understood reactions. For example, the production of Methane as propellant for the back transit is a mature process on earth , but conventional methanation reactors maximize yield with high temperatures and pressures, which require heavy periphery. In this context, the use of recyclable Fluoropolymers as an alternative reactor material, though never considered on earth, becomes advantageous for Martian exploration due to their reusability and lower density compared to typical steel reactors. Moreover, the concept of ISRU requires solid ground to start from. All technology contributing to a safe execution of space operations should be robust and somehow tolerant for the conditions at the landing site . Thus, the implementation of polymeric reactors for applications beyond earth comes with the challenge of suitable and robust catalysts.