We have previously used this approach for designing robust 2D molecular materials, presenting an unprecedented chemical/physical tunability and suitable to be integrated into mechanical resonators. This approach is based on the easy synthesis of pre-functionalized bulk layered materials that are micromechanically exfoliated. Thus, one can obtain an isoreticular family of 2D molecular materials, presenting different magnetic properties or wettability. Herein, we describe the synthesis and characterization of the fluorinated isoreticular analogue of this family, MUV-1-F, a 2D coordination polymer analogous to fluorographene, with long-range magnetic order and well-defined layered crystals, appropriate to prepare 2D magnetic molecular materials.