spheroids, polymer-lipid hybrid nanoparticles, polymeric nanoparticles, and self-emulsifying systems have been reported as drug delivery systems of artemisinin and its derivatives . Fe3O4@SiO2 mesoporous spheres carried artemisinin and released it in PBS at pH 5.3, 7.4, and 9.8, reaching 86.2% in acidic conditions over 72 h . Artesunate, a derivative of artemisinin, was loaded in citratefunctionalized hydroxyapatite nanorods and released in PBS at pH 5.4, 6.8, and 7.4, with a maximum release percentage at pH 5.4, exhibiting a burst release of 70.79% in 6 h and a total release of 95% at 120 h .