For the cannabinoids the analytical column was a Kinetex XB-C18 column (50 x 1.0 mm, 2.6 µm. Phenomenex). The column temperature was set at 40°C. Mobile phase A was H2O with 0.1% HCOOH and mobile phase B: CH3CN with 0.1% HCOOH. The ballistic gradient started at 77% B and was linearly increased to 95% B from 0.5 min to 3 min and kept constant for 0.5 min (95% B) followed by re-equilibration time of 1 min (10% B). The total LC run time was of 4 min. The flow rate was set at 0.1 ml/min and injection volume to 10 μL. For vDMS-SIM/MS same settings were applied as shown in section 1.3.1. For LC-MRM/MS analysis Argon was used as CID gas (270 kPa) and the vDMS was switched off. Data were acquired and processed using LabSolutions (version 5.99 SP2, Shimadzu Corporation, Kyoto, Japan). Table summarizes the LC, MRM and DMS parameters of five cannabinoids.