We report a one-pot strategy to achieve phenanthridine 3. 38 Further increase of reaction temperature and changing the solvent to DMSO has no effect on the reaction. So, the set of optimal reaction conditions were finalized to be Pd(OAc)2 (5 mol %), PPh3 (0.25 equiv.), Cs2CO3 (1.5 equiv.), in DMA (3 mL), at 90 °C, for 3 h (Table .1, entry 10). Once we got the standard conditions for the cyclization procedure, we have generalized our methodology synthesizing various types of phenanthridine and analogous derivatives in excellent to good yields. The results are shown in the Table .2. Different substituted phenanthridines 3.38a-f were synthesized from the corresponding 2-bromobenzaldehydes 3.37a-f in good yields. The results in the Table .2 shows that this methodology is well tolerated both the electron-donation and electron with-drawing functionalities such as, nitro, methyl, methoxy group in the coupling partner 3.7. equiv.), DMA (3mL), 90 °C, 3-5 h.