Penicillium sclerotiorum, a filamentous fungus, holds a distinctive place in the taxonomy of the Penicillium genus. Its unique characteristics, include monoverticillate, vesiculate conidiophores, vivid orange to red colony hues, and strains that produce recognizable orange sclerotia. Initially classified in the subgenus Aspergilloides, section Sclerotiora, it has been identified in diverse regions, suggesting a cosmopolitan distribution, albeit infrequently reported. Isolates commonly originate from soil, textiles, house dust, diseased grapefruit and stems, and also found as a potential endophyte of Coffea arabica berries. Recent classifications by Houbraken & Samson, place P. sclerotiorum in Penicillium subgenus Aspergilloides, section Sclerotiora, revising the concept initially proposed by Pitt et al. The fungus under investigation was identified as a strain of P. sclerotiorum based on morphological characteristics observed during inoculation experiments. The fungus exhibited radially sulcate or wrinkled mycelia, often with orange droplet exudation. Aerial mycelium displayed color variation, ranging from white or buff at the margin to saffron or deeper orange red near the inoculum, accompanied by scattered penicillin. The morphological characteristics, including monoverticillate penicillate conidiophores and ellipsoidal conidia, aligned with the variation described for P. sclerotiorum van Beyma, although the mycelial extension values were lower than typically reported for the species.