Triazoles are another example of moieties preserved from parent compounds to TPs. Out of the triazole compounds in PubChem, 62 have recorded TPs (12 Jan 2024) . This corresponds to 233 unique reactions, out of which the triazole moiety is retained in 88% of the cases, showing its high stability. While usually not acutely toxic in low doses, triazoles may cause several severe chronic toxic effects such as endocrine disruption and neurotoxicity . Triazole substances such as benzotriazoles are present in the environment at high levels . Thus, the retention of this functional group and other PMT/vPvM moieties may be concerning from an exposure point of view, supporting the idea that grouping based on retained moieties or TPs is relevant to obtain comprehensive and inclusive groups for PMT/vPvM substances.