Since a large portion of the volatile thermal reaction products of ∆ 8 and ∆ 9 THC formed under vaping conditions derive from their cyclohexene ring, we focused current experiments on CBN-acetate. CBN-acetate contains a second aryl, rather than a cyclohexene ring (Figure , see CBN-OAc-D 3 ) that renders it relatively stable, thereby reducing the analytical complexity of its corresponding aerosol samples. In addition, CBN and CBN-OAc are crystalline and thus easier to purify and handle compared to THC or CBD and their acetate derivatives.