Introduction: Carbamate-bearing molecules play an important role in modern drug discovery and medicinal chemistry . Carbamates are widely utilized as a peptide bond surrogate in medicinal chemistry. This is mainly due to their chemical stability and capability to permeate cell membranes. Furthermore, organic carbamates serve an especially important role as optimum protecting groups for amines and amino acids in organic synthesis and peptide chemistry 2 . Transcarbamation is a process interchange of the alkoxy moiety in carbamate moiety. Transcarbamation increases number of functional group transformations reactions can possibly executed than its mono carbamate, without effecting the other functional groups, which further broaden the scope of using carbamate as protecting group .