catalysts for catalytic asymmetric SN2 reactions of fluoride, 7 the use of a chiral fluorinating reagent, and the asymmetric hydrogenation of fluoroalkenes using homogeneous catalysts containing rare transition metals (Rh, Ir). Direct fluorination of enantioenriched alcohols with reagents such as DAST is perhaps the most accessible approach, but it is potentially hazardous to scale-up and promotes competing elimination processes often resulting in low product yields. The development of readily scalable and accessible methods for the enantioselective preparation of alkyl fluorides remains a challenge.