Therefore, precise control of NO concentration opens promising possibilities for target therapy including anticancer therapy. For controlled delivery of nitric oxide, extensive efforts are being made to develop novel NO-releasing materials such as liposomes, nanoparticles, macromolecules. Short lifetime (~5s) in living tissues and limited diffusion range of nitric oxide imply the use of methodologies which rely on the triggering of NO release using external stimulus, for example, light radiation , X-ray radiation , or ultrasound . Visible and NIR light represents a smart fine-tunable and non-invasive tool for practical usage due to deeper penetration in biological tissues. Therefore, development of such photoactivatable NO-donors is highly desirable.