Protein sets. We analyzed a total of 3,885 proteins related to the immune system. All proteins were extracted from the gene ontology (GO) terms: 0002376 immune system process, 0045087 innate immune response, and 0002250 adaptive immune response using David Bioinformatics Resource () , the International ImMunoGeneTics information system () , the InnateDB database () , and a study of Patel et al., focused on essential proteins for cancer immunotherapy . On the other hand, Gordon et al., identified 332 human proteins physically associated with 26 of the 29 SARS-CoV-2 proteins using affinity-purification mass spectrometry . Lastly, we performed a PPi network between immune system proteins and human proteins physically associated to the SARS-CoV-2 proteins.