Similarly, we measured also the intrinsic rate adsorption of a protein on PDMS surface. Here, since the reaction occurs inside a microchannel, the reactants and the products do not get exposed to atmosphere, yet elastocapillary effect allows in-situ measurement of the reaction rate and consequently, the rate constant. In fact, this method not only tracks the dynamics of a physical and chemical event, but it also throws light on how energetics of an interface alters because of the formation of a new chemical bond or evolution of a chemical species at the reactive interface. It is important to note also that in contrast to several existing techniques, this method is benign; it does not require fluorescent tagging of the molecules, and doesn't involve application of electric field that often results in undesired charging of the materials, nor it depends upon transparency or opacity of the solid or the liquid being handled. While we have used Sylgard 184 elastomer for making the soft (Young's modulus ~1.2 MPa) layers, the effect can be amplified further via use of an even softer (Young's modulus ~0.1 MPa) material (Fig. ) and via further optimization of diameter and wall thickness of the channel. Furthermore, since the science of surface functionalization of PDMS is very reach, variety of methods that have been developed in literature for this purpose, can be integrated with the Elastocapillary effect, which will enable studying in situ processes involving different kinds of chemical and biological samples. Thus, this method is expected to be useful also for host of sensing applications, where direct measurement via conventional methods remains ineffective.