Interestingly, versicolorin C (65) displayed selective potent antibacterial activity against both E. coli and V. parahaemolyticus with MIC values of 1 μg/mL and, against V. anguillarum and Edwardsiella ictaluri with MIC values of 4 and 8 μg/mL, respectively, whilst the closely related congener isoversicolorin C (66) displayed selective potent antibacterial activity against both V. alginolyticus and Edwardsiella ictaluri with MIC values of 1 and 4 μg/mL, respectively .