Aggregation-induced emission luminogens (AIEgens) comprise a series of fluorescent dyes that exhibit weak emission in dilute solutions but can significantly enhance emission upon molecular aggregation. Unlike conventional fluorophores that suffer from ACQ effects, AIEgens can achieve strong emissions even in aggregate states. Yet, there exist limited studies presenting tetrazine fluorogenic probes that exhibit aggregation-induced emission (AIE) properties post-iEDDA reaction. Although one study reported a high IAC/IBC of up to 1779-fold, it did not explicitly address the mechanism and relation between AIE properties and the high IAC/IBC result. Furthermore, the generalizability of such molecular design strategies remains unclear.