without the requirement for attachment to protein carriers. The Silipo group at Napoli has been working on deciphering the molecular level details of host-pathogen interactions of commensal and harmful bacteria. Owing to our long-standing interest in chemical synthesis of exclusively bacterial rare sugars and related glycoconjugates we took up a collaborative study with Silipo group focussing on the trisaccharide II and its related frameshifts. Very recently, Yin and co-workers reported chemical synthesis of a linker attached trisaccharide I, which prompted us to disclose our results on the total synthesis of trisaccharide II.