Throughout our discussions, a recurring theme has been the importance of model interpretability. By analyzing the feature rankings in Figure and 2g, we can make several inferences pertaining to chemical trends at a global level. For instance, based on feature importance, the number of -COOH fragments appear to be highly correlated to toxicity. Similarly, more toxic molecules tend to have lower bicyclic fragments (an average of 0.15 for fatal, 0.26 for toxic, and 0.33 for safe molecules) and ether oxygens (an average of 0.13 for fatal, 0.30 for toxic, and 0.27 for safe molecules). Similarly, less toxic molecules tend to have higher carbonyl oxygen fragments (those excluding the -COOH group)an average of 1.62 for safe, 0.96 for toxic and 1.40 for fatal molecules. As is evident from these values, in several cases, trends may not be linear. For instance, as can be observed in Figure , fatal molecules may have properties that fall between those of safe and toxic molecules.