[CIPS: Cyclic Invariant Periodic System.] The classes are marked with colors as in Table . The new arrangement of amino acid pairs (chemically also meaningful) shows that the quantities 58, 68, 78 are obtained again, as we find in the original arrangement (Table .2). [Revalidation of the principle: "with as few of the same quantities as possible (signifiers) to be designated as many different qualities as possible (signified)" (Discussion, I).] Everything is the same as in: with the fact that here distinctions (in the number of atoms) are given in the subset of polar-charged AAs (red) and subset of all others.