As the enantiopure precursors predetermine the chirality of the coordination species, from the perspective of molecular symmetry, employing this approach leads to the MOCs, which are unlikely to racemise. Generally, in such an approach chirality is either induced by the spatial arrangement of the tetrahedrally or octahedrally coordinated metal centres (vertices-directed assemblies), or by optically pure organic ligands that are sustained by strong covalent bonds (edge-or face-directed assemblies).