In this equation, I represent the intensity of each signal in the 1 H NMR spectrum, and R denotes the ratio. Analysis of the various ratios among all possible conformers reveals that the synperiplanar (sp) conformer is predominant for compounds 4a-b, while the antiperiplanar (ap) conformer is favored for compounds 4c-d. For compounds 4e-h, the syn/anti-periplanar conformers are nearly in equal proportions. has demonstrated that the Z isomer of acrylohydrazides is characterized by a singlet around 14 ppm corresponding to the NH proton. The absence of a singlet (duplicated) around this chemical shift in our proton spectra (Figure ) suggests the absence of the Zc=N isomer. However, the lack of correlation between the NH proton and the azomethine fragment in the NOESY spectrum of compounds 4h and 4f confirms the presence of the Z(C=N) isomer, contradicting Palla et al.'s findings. Regarding compounds 4a-b and 4e, the emergence of a weak correlation between the NH proton and azomethine (N=CH) and azoethylidine (N=C(CH3)) fragments in the NOESY spectrum (Figure ) confirms the presence of the E(C=N) isomer. Table summarizes the calculated ratios relative to the duplicated NH signal. These results indicate that the syn conformer is predominant for compounds 4a-b (thus, the stereochemistry Ec=c sp EC=N), while for compounds 4c-h, the anti conformer is favored. It is noteworthy that the proportion of the anti conformer decreases in favor of the syn conformer when transitioning from compounds 4c-d to 4g-h and from 4g-h to 4e-f. This variation in the proportion between syn/anti conformers in compounds 4c-h may be linked to the diverse aromatic aldehydes used for their synthesis, as well as potential interactions during characterization.