In addition, the ORR has been studied on these Pt(Ge)/2D catalysts by investigating the OOH dissociative pathway has been investigated based on the spontaneous OOH* dissociation. The analysis of the free energy indicates that not only the Pt atoms, but also Ge and the support sites are involved in stabilizing the ORR intermediates, creating new active sites at the cluster-2D interface. Unfortunately, all the systems studied in this work yield too high overpotentials, leading to a poor ORR performance. Pt atoms, due to the excessive charge transfer from the support, Ge atoms and support, all provide too oxophilic active sites for the oxygenated species. As a result of this oxophilicity, O* and OH* get overstabilized. This strong adsorption then translates in uphill steps and high coverages of O* and OH* intermediates. All in all, the catalysts tested herein may not be suitable candidates for the ORR in acidic conditions.