The nanoPharos database (db.nanopharos.eu/), developed within the H2020 NanoSolveIT (www.nanosolveit.eu, ) and NanoCommons projects, is promoting accessibility, interoperability and reusability of curated datasets in a ready-for-modelling format. The nanoPharos database has been designed under the FAIR data principles to also include computationally derived data from simulations of nanomaterials at different levels of complexity. The database was further extended to include nanomaterials characterization data that can be enriched with a series of atomistic, molecular and structural descriptors. The database offers the possibility of including different batches and instances of the same nanomaterial, so as to monitor any physico-chemical transformations across its entire lifecycle. Thus, it is possible to use a single starting ERM and follow nanomaterial transformations/changes in different laboratories and/or projects and under different environmental conditions. The nanomaterials data can be linked with biological effects data to support complete in silico nanosafety evaluation. Currently, the NanoSolveIT project has registered 57 ERM identifiers to uniquely identify which nanomaterials the information in the database relates to. An additional 25 ERM identifiers were added to the nanoPharos database for a dataset derived from a recent publication . Because this dataset was a subset of the original dataset, which was in NanoWiki 6 , the ERM identifiers were also added to NanoWiki. The nanoPharos database offers users the ability to define specific nanomaterials, enrich the main structure with molecular and atomistic descriptors, which can be linked with a specific ERM. The system offers the ability to define separate batches of the same nanomaterial, directly linked to the original material and to the subsequent biological assays. In this way, it is possible to track the lifecycle of the starting nanomaterial and its different batches using the ERM.