The transposase IS66 central (IPR004291) has a central domain. This domain is present in Agrobacterium tumefaciens' transposase IS66. Transposases are necessary for efficient DNA transposition. It is possible that IS66 may cause genetic and structural variations in the cephalopod Ti plasmid's T region and vir region. We refer to the C-terminal region of the insertion element IS66 transposase as Transposase IS66 C-terminal (IPR039552). We refer to the zinc-finger region at the N-terminus of the insertion element IS66 transposase as transposase IS66 zinc-finger binding (IPR024474).