It clearly gives evidence for overall good reproducibility (note that in manual synthesis deviations exceeding 100% are not uncommon). While one could discuss each comparison of conditions in more detail, a direct conclusion from these tests is that the standard deviation is generally around 10 % of the mean average size. This means, however, also that individual deviations can be quite significant, showing individual errors of up to 50%. This proves that at least a minimum of statistics is required in order to find the true average. A single experiment or even a set of two datapoints may be misleading and the 10% deviation is only achieved with a significant number of experiments. While this is by itself an important observation, it underpins again the need for automation to carry out the increased number of experiments required. As a first measure of control, all experiments in the following were programmed to be carried out in triplicates.