The solvation study suggests that a solvent has the potential to strongly alter the NSCD of certain nuclei. In the presented case, DMSO enhances the NSCD signals of the bridged C2 and C7 significantly while C 6 H 12 and CHCl 3 did not bring about any striking changes compared to the gas phase calculations. It is interesting to note that previous studies of the influence of implicit solvent on the related NSOR effect showed only quantitative difference, affecting proportionally the strength of the signal, but not its sign. This suggests a larger importance of solvent effects for NSCD than for NSOR.