As a result, new attractive perspectives will open in combination for instance with advanced technologies such as 3D printing, and being able to build various structures with precise control over material composition, geometries and mechanical and biological properties. Hybrid hydrogels-based bio inks could be used to fabricate tissue-specific structures with a high degree of customization. By mimicking native matrices, promoting cell growth, proliferation and differentiation, they will become the ideal scaffolds for promoting the regeneration of tissues such as cartilage, bone and skeletal and cardiac muscle. Additionally, by achieving a close resemblance with the recipient tissue, they will raise the rate of successful integration and functionality.