The COCONUT curation pipeline automatically processes and maps metadata from data sources. For new entries, the natural product name is imported from the data source. For molecules already existing in the database, the name from the data source is added to the list of synonyms. Organism and sample location information, when available, are mapped to ontology terms using the EMBL-EBI Ontology Lookup Service (OLS4) or the Global Names Finder API (IRI and rank) . Citation information and provenance data are imported and mapped based on DOI. Europe PMC Restful Web Service and Crossref REST API are used to fetch citation metadata. Geolocation, synonyms, CAS ID, IUPAC names, and other metadata are imported and mapped. Using CDK and RDKit, a range of molecular properties, descriptors, and fingerprints are computed. Each molecular entry was given an NPLikeness score (5) implemented in RDKit, a metric used to assess how closely a given compound resembles a natural product.