In the light of what has been said above, the elimination of various PG strategies from the aforementioned synthesis of NInC hybrids brought about the modified NInC 27 (Scheme 6), which in point of fact, exhibits better physical stability than that of its corresponding NInC 12, such that it was, to some extent, feasible to purify the former using flash column chromatography on silica, which was otherwise impossible for the latter, thus rendering the monumental objectives of symbiotically associating InCs with nitrofurans in a single molecule of therapeutic potential fruitful.