Poly(butylene succinate) (PBS) is a polyester derived from bio-based monomers and is receiving an increasing attention for its potential biomedical applications due to its good biocompatibility and biodegradability . These properties make it suitable for various biomedical applications, including drug delivery systems and medical devices , . Tissue engineering is the most widely researched biomedical field for PBS application where different forms (films, scaffolds) are being developed . While PBS holds promise across a spectrum of applications, the study of its biodegradability must be approached with precision, given its potential influence on diverse fields of use. Consequently, the assessment of PBS degradation should be tailored to align with its specific application domains. Since the neat PBS is stiff and brittle material , , it limits its application in certain biomedical contexts. To overcome this limitation, PBS-based copolymers are becoming more important since they offer easy modification of thermal and mechanical properties, and the rate of biodegradation can be easily altered by the type and amount of comonomeric unit(s). PBS-based copolymers are usually synthesized by polycondensation reaction by introducing different building-blocks. For example, in our earlier work, plant-derived dilinoleic diol (DLA-OH) and poly (ethylene glycol) (PEG) as soft segments were introduced to the PBS chain . This allows for the creation of multiblock copolymers with a wide range of physico-chemical and mechanical properties by adjusting the hard and soft segments ratio , , resulting in materials with rubber-like elasticity.