As can be seen from Fig , the probability distribution of TOP (𝑃(𝑞 𝑡𝑒𝑡 )) of bulk water is represented in orange for comparison purpose (with Protocol-1 and Protocol-2), which has its peak value at 𝑞 𝑡𝑒𝑡 ~ 0.75. In the second column of Fig , we provide the difference of 𝑃(𝑞 𝑡𝑒𝑡 ) between bulk water and different systems under consideration and the magnitude of its non-zero value is a measure of deviation from the bulk water behavior. In the structured region (𝑞 𝑡𝑒𝑡 > 0.5), peak height increases as wt% of reline increases.