We used this design template (Figure ) to synthesize asymmetric Brønsted acid-Lewis base organocatalysts with a hydrogen bond acceptor (amino group) and either a strong Brønsted acid (carboxylic acid) or a hydrogen bond donor (thiourea). Previously reported organocatalysts such as those shown in Figure contain several stereocenters. Since the number of possible diastereomers grows exponentially with the number of stereocenters, it is desirable to keep their count as low as possible. In comparison, our compounds are purely axial-chiral since they possess a planar benzene ring instead of a cyclohexane unit, reducing the number of distinct stereocenters from three to one.