An overview of DFTB-based excited-state dynamics with applications to both real-time time-dependent DFTB (RT-TDDFTB) and nonadiabatic dynamics has been presented in this review. In both of these formalisms, a series of didactic tutorials and examples demonstrate how each approach is used in practice to reveal dynamical effects in chemical/material systems of contemporary interest. Within the sections on RT-TDDFTB, we demonstrated how this computational approach can be used to either calculate an electronic absorption spectrum or probe the electron dynamics of a chemical system in the presence of monochromatic light. Both of these choices give a different but complementary view of electron dynamics in large systems, as demonstrated by our example on plasmonic nanoparticles. Within the sections on nonadiabatic dynamics, we explained our implementation of CPA-FSSH-DFTB, which was applied to study charge transfer dynamics in an organic photovoltaic system. By computing the charge transfer time-scales in a model PCBM-PT system, which are in good agreement with earlier ab initio results, this approach shows immense promise for probing charge-transfer dynamics in even larger mesoscopic systems. Together, both of these examples in RT-TDDFTB and nonadiabatic dynamics extend the computational efficiency of DFTB to emerging areas of excited-state chemical dynamics, creating an exciting opportunity for understanding these dynameffects in large, complex systems.