The conformer generation results above, suggest that our generative model covers the local free energy minima of small molecules well and that we may cover the conformational space of small molecules faster than regular MD simulations. We illustrate that this indeed is the case through the following example. We find SMA-MD samples states present in the long RE simulations separated by barriers that are Furthermore, we show that SMA-MD generates samples in a more statistically efficient manner by comparing the ensemble potential energies. We do this by computing the difference in average ensemble energies and the Jensen-Shanon divergence (div) between energy histograms. We show in Figure (a) that SMA-MD generates more similar energy averages and distributions to RE than MD, and that the agreement with RE is very high.