The bubble plot in Figure provides another means for data visualization. Here, only the number of experiments with high quantities are included. It can be readily seen that product 5a is associated with reaction in DMF with 16 of the 20 reaction profiles recorded when DMF was used (5 temperatures for 4 reaction times) show relatively high quantities of 5a. Conversely, when the reaction is performed in propylene carbonate, no reactions exhibit high quantities of 5a. However, 14 of the 20 reactions show high levels of 6a. Additionally, 12 reactions show relatively high amounts of acetanilide 17a. Again, that high amounts of α-arylation products 14a and 15a are only associated with MEK, which is as expected, validating our approach. Heatmap analysis. To garner further mechanistic insight, we used heatmaps to visualize correlations between products. The heatmap in Figure shows the strength of any correlation across all reactions between the various products. The data includes reaction solvents, temperatures and times. For example, the similarity of MEK α-arylation products 14a and 15a is clear from the dark red block indicating a positive correlation close to 1 (highlighted by a yellow box). The strongest negative correlations (dark blue) are between 2-bromo-benzamide 1a, and the block of positively correlated products, aniline 16a, biaryl diamide 4a, 2a-derivatized compound 6a and phenanthridinone 2a (the major product of the reaction). This negative correlation highlights that significant consumption of 1a is correlated with formation of phenanthridinone 2a and the most prevalent side-products 4a and 6a.