When following the tree's first branch to the right-glycosylations with glycosyl donors that do not have a -1 configuration (often equatorial) of the C-2-the second decision node is whether the C-5 is a methyl group (6deoxy glycosyl donor) or not. The most well-known 6-deoxy sugars are L-rhamnose and L-fucose but since Lrhamnose has a -1 C-2 configuration (as illustrated in Figure ), L-rhamnosylations would end up in the left branch from the root node. The donors in the 303 samples in this internal node were determined to mostly be L-fucose derivatives. If true, the glycosylations are predicted to be α-selective, albeit with a low accuracy. The next decision is made by asking whether a C-5 substituent is present or not, which would be true for a pentose in its pyranoside form. If a C-5 substituent is present the glycosylations are predicted to be β-selective. The last question in this branch is whether the donor is 4,6-benzylidene protected, which is also a decision node in Expert Tree 1, if not the majority of the glycosylations are β-selective.