I introduced two new directories: QFConfs_DiversityLevel0 and QFConfs_DiversityLevel1. Data files in these directories require some explanation. The qfconfsearchDFT.x application uses RMSD pairwise alignment-based deduplication via the C++ APIs of RDKit, by default, only for molecules with no more than 40 atoms. We include hydrogen atoms in RMSD alignments and deduplication because we aim to retain important conformations with different hydrogen orientations. However, RMSD calculations are computationally expensive and scale poorly with molecular size. Some tests showed that RMSD-based deduplication could be more expensive than all ab initio DFT-D4 calculations. Therefore, we limited RMSD-based deduplication to molecules with up to 40 atoms and developed an alternative scheme for larger molecules. This alternative scheme is new and experimental, currently set conservatively, meaning it sometimes retains structures that are very similar. This conservative approach is preferable, as eliminating duplicates later is easier than recovering missing conformations, which would require repeating expensive calculations. The QF_DiversityLevel0 and QF_DiversityLevel1 directories contain post-processed deduplicated conformations. We used a 0.3 Å RMSD limit in the QF_DiversityLevel0 directory and a 0.6 Å RMSD limit in the QF_DiversityLevel1 directory. Note that if the energies of two conformations differ by more than 0.3 kcal/mol, we keep both, regardless of the RMSD difference in geometries. Further deduplication or different deduplication starting from the conformations in the QFConfs_ALL directories is possible, and users can easily perform this themselves. Unfortunately, one structure failed to process, leaving us with 1,599 instead of 1,600 structures in vacuum and 1,609 instead of 1,610 in aqueous continuum for the FDA-approved drugs database.