As TFA is accumulating in diverse ecosystems, researchers should focus on non-traditional exposure and impact pathways that affect biogeochemical processes. Despite the extremely high plant uptake of TFA, controlled uptake experiments were rarely performed and reported for TFA. Zhang et al. performed a set of hydroponic experiments with TFA and other ultrashort and short PFCAs. Here, the root uptake was exceptionally high for TFA when compared to other PFCAs, e.g., the root concentration factor of TFA was >1600 L/kg 56 , two orders of magnitude higher than usually determined for PFCAs with 3-5 perfluorinated carbons (CFx) in similar experiments . Chen et al. found a similar pattern for chain length dependence of PFCAs. The field-based soil-water distribution coefficients (Kd) -Kds were higher than expected for TFA (and PFPrA), demonstrating a trend opposite of the commonly observed and reported Kd decrease from 11CFx to 3CFx of PFCAs and PFSAs . This indicates that the interface partitioning of TFA and interactions with soils and plants need to be researched further and accounted for in assessing its environmental fate and behavior properties, particularly (bio)accumulation potential. Such research needs to be extended to agricultural systems, such as the transfer from crops containing elevated levels of TFA to livestock (meat and milk) and human diets, as well as a transfer of TFA from plants through diverse food webs, similar to previous research on other PFAS .