Next, the scalability of e-HAT was evaluated in both batch and recycle flow on three different transformations; isomerization, alkyne reduction, and cycloisomerization (Figure ). The isomerization reaction with Conditions A was tested with compound 61 on a 1 g scale using the commercial Vapourtec ion recycle flow system (Figure ). By keeping the same parameters with 0.8 mA/cm 2 current density and 1 ml/min flow rate, the product was obtained in 92% yield. In a similar fashion, the alkyne reduction was demonstrated on a 10 g scale using a batch setup to achieve a complete conversion of 64 and obtain the desired product (65) with a 76% isolated yield (11:1 of E:Z isomeric ratio, Figure ). Finally, the cycloisomerization reaction with Conditions B was conducted on a 100 g scale with compound 61 using a recycle flow apparatus containing four reaction cells (Figure ). After optimization, 100 grams of 61 were successfully converted to product 27 by keeping the same current value of 2 mA/cm 2 (compared to 0.2 mmol scale) with a catalytic current of 0.6 F/mol to achieve complete conversion (73% isolated yield).