A-pBuOzi-A based formulations followed the similar trend until day 5, however slightly higher loss in solubility was observed at day 30 (≈ 30-40 %). The A-pPrOzi-A displayed very poor solubilizing capacity for CTZ so it was not further considered for long term stability study. In the case of A-pPentOx-A triblock copolymer, all the employed CTZ was completely solubilized in freshly prepared formulation. However, the formulation tend to agglomerate or precipitate fast and at day 1, a solubility loss of around 50% was observed and until day 30 this loss further increased to 90%.