As our predictions, we submitted the outputs from HYBRID as our predicted poses during the challenge even though we used MD simulations to assess the stability of these poses. The poses were not minimized or equilibrated to relax any steric or Coulombic clashes prior to submission. An alternate approach would have been to submit poses relaxed by MD. Hence, in Stage 1b, we decided to have two separate submissions: i) The initial binding poses before MD corresponding to the outputs generated by HYBRID. Similar to Stage 1a, these poses were not minimized or equilibrated to relax any steric or Coulombic clashes prior to submission. and ii) the final binding poses at the end of our 14 ns long MD trajectories. Our objective was to see how the relaxed binding poses from the MD simulations fared compared to the initial starting conformations.