The binding constant of 10 6 M -1 is almost the same order as those of albumin and aptamers in aqueous buffer. With this in mind, 1 was then functionalized into the surfaces of a mesoporous resin by an SN2 reaction between the phenolic oxygen and resin-bound epoxides (Fig. ) using a procedure analogous to the previously reported method, for solid-phase extraction with the resin-bound analogue: In the presence of 1 (1.2 mM) and excess triphenyl phosphine (PPh3), the suspension of the base (EG40) in N,N-dimethylformamide (DMF) was stirred at 110 ºC for 4 h under a steady flow of Ar in the dark. The end of the reaction was determined using HPLC analysis. The obtained resin was extensively washed with methanol and toluene using a Soxhlet extractor, and then dried to obtain poly1. The obtained material was characterized by elemental analysis, titration of the functionalized amino acids (Table ), and the adsorption isotherms for the gas phase (Fig. and Table ) and liquid phases (Figs. 3b).