The first thing to notice from Figure is that the alkane and alkene carbons aggregate in different and well-separated clusters, as does every other carbon-centered chemical moiety in the database. This was already observed and discussed previously in .The second observation is that all the vectors of the transformation appear to be equal to a large extent. The extent to which the vectors are equal can be quantified by considering the average "oxidation vector from alkane to alkene" and use this as a proxy to transform the embedding of any reactant alkane to its alkene counterpart, that is,