We have demonstrated recently that the organic ligand, AdDB , shown in Scheme 1 and similar systems form isostructural crystals with first row, bivalent metals (i.e., manganese, iron, cobalt, nickel, copper and zinc) . The crystals have two types of continuous and chiral channels aligned along the crystallographic c-axis. This structural feature is atypical , and has great potential for post-functionalization by size-selectively inclusion of other components as demonstrated in this study. The abovementioned bivalent metal cations favor an octahedral geometry with four pyridine ligands coordinated in the same plane, making it possible to predict the crystallographic structure for other metals favoring a similar coordination geometry. Although the use of this series of metal cations afforded a diversity of different morphologies, for most cases both the crystal uniformity and monodispersity are high.