The canonical tautomer was determined, and, from the InChIKey strings of the canonical tautomer, the duplicate compounds were removed. The same curation workflow was applied to two reference datasets employed to compare LANaPDB: COCONUT and FDA-approved small-molecule drugs, version 5.1.10 (released by DrugBank in January 2023). In LANaPDB, during the curation process, before the elimination of duplicate molecules, a Venn diagram (Figure ) was constructed in the Python programming language employing the Venn module, from the InChIKey strings of the molecules.