As the predominant antibody isotype of the immunoglobulins, IgG is vital for humoral adaptive immunity and acts as an opsonin for pathogenic antigens .On a typical Transferrin (77kDa) is an iron transporter that is also involved in macrophage activation . Ahigh band intensity was observed for transferring on PCL fibers, which may translate to a potential for macrophage activation. Coupled with substantially higher levels of complement C3