We propose a new way to identify AAs based on the transduction of their amphoteric properties with field-effect transistors (FETs) that can generalize access to protein sequencing. Using FETs to distinguish proteins by their isoelectric point and studying the variations of the surface potential was already considered by the inventor of the ISFET, P. , but it was discarded because the protein charges often lay above the Debye length and thus are screened by the ions in solution.