Curcumin (CUR) treatment for prostate cancer cells was made more effective by hydroxypropyl methylcellulose . Comparing CUR alone to CUR-conjugated cellulose, substantial apoptotic alterations were observed. Comparing cellulose to other carriers including -cyclodextrin (CD), poly(lactic-co-glycolic acid) (PLGA), MNPs, and dendrimer, cellulose likewise demonstrated the maximum cellular absorption . For the medication delivery of CUR, TOCNF, and MOFs such as zeolitic imidazolate frameworks (ZIF-8) and material institute of Lavoisier (MIL-101 (Fe)) were utilized (Figure ) . The composite of TOCNF/ZIF-8 allowed 3D printing to transform the material into a 3D network . MOF powder may be printed using cellulose. In-situ synthesis uses it as a template and binder for MOFs. Under physiological pH (5.5), the materials can release the CUR medicine . A simple procedure of 3D printing of cellulose/ZIF-8 was also reported using a binder-free procedure (Figure ) . The synthesis procedure is simple and can be commercialized.