We propose MolPipeline, a Python package unifying cheminformatics tasks for molecular machine learning in a single scalable pipeline implementation. Like preceding tools, MolPipeline incorporates the standard open-source libraries RDKit 7 for cheminformatics and scikit-learn 8 for machine learning. With MolPipeline , we aim to enable flexible automatic end-to-end learning from a molecular data set to a trained machine learning model ready for productive deployment. The key features of MolPipeline are