Synthesis of ester derivatives of DHLc 10 mM of DHLc (2.76 mg) and 100 mM of the corresponding vinyl esters were dissolved in the solvent mixture in the presence of 3 Å molecular sieves. 1 mL of the resulting solution was introduced into a 2 mL vial containing 20 mg of Novozym 435 and 3 particles of 5 Å molecular sieves. The vials were placed in an orbital carousel rotating shaker (Thermo Scientific Tube Revolver) at 35 rpm in an oven at 37 °C for 48 h. The reaction mixtures were then filtered on 0.2 µm PFTE filter into 2 mL Eppendorf tubes and concentrated under 8 mbar at 35 °C in a Thermo Scientific SpeedVac system for 2 h. DHLc-propionate was obtained at 100 % (+/-5 %) yield. The synthesis proceeded in accordance to the literature. Potassium hydroxide (0.5 eq.), palladium (II) acetate (0.4 eq.) and 1 eq. of carboxylic acid were weighed in a 25 mL round-bottom flask and dissolved in vinyl acetate (0.1 M). The reaction mixture was stirred overnight at 40 °C. The resulting mixture was cooled to room temperature, filtered over a celite pad and washed with dichloromethane. The solvents were then removed under vacuum and the crude product was purified by flash column chromatography.