The high chemoselectivity inherent to many single electron processes could be leveraged to delete functional group (FG) manipulations and protecting group (PG) chemistry as demonstrated in Figure . For instance, aryl bromide 86 bearing a free carboxylic acid could be easily coupled to 10-RAE followed by acidic workup to deliver 5 directly. In contrast, the previous route to this molecule involved a tedious 7-step construction with only one of those steps being strategic (C-C bond formation). Similarly, Bpin-containing aryl bromide 88 could be easily coupled to 10-RAE followed by Suzuki coupling and acidic workup to deliver aminoalcohol 1. The previous synthesis of 1 required Suzuki coupling with an elaborated aryl bromide (4 steps to synthesize) and an expensive boronate ester. As the Bpin group can be preserved in Ni-electrocatalytic coupling, this strategy readily affords the functionalized boronate ester 89, offering a more convenient intermediate that enables the use of inexpensive bromothiazole as a coupling partner thereby lowering both the cost and labor required for synthesis.