Temperature dependence of the VSC rate constant. Experimentally, it was found that VSC induces changes in both effective activation enthalpy and activation entropy when using the Eyring equation to interpret the change of the rate constant , which remains to be theoretically explained. We emphasize that based on our current theory, the VSC modification mechanism is not due to the direct modification of the Entropy or Enthalpy, but rather through the mechanisms summarized in Eq. 11 (for lossless regime) and Eq. 1 (for lossy regime). However, if one chooses to interpret the change of the rate constant through these enthalpy and entropy changes, then the current theory in Eq. 17 can indeed explain both changes. Using the Eyring equation, the temperature dependence of the reaction rate constant is