In Figure , the temperature is increased from 263 K to 283 K. The cluster formation 230 potentials decreases by many orders of magnitudes for the "pure oxyacid" clusters, owing to 231 the relatively weak bonding in the clusters. On the other hand, the "oxide" clusters, that 232 exhibits very strong bonding, is barely affected by the temperature change. This means that 233 "iodine oxide" nucleation is not limited by evaporation of the initial clusters due to ambient 234 heat, but rather the amount of available oxide in the gas-phase. The "mixed acid" nucleation pathway can be seen to decrease by around two orders of magnitude. The high amine concentration scenario is only competitive with "oxide" nucleation at low iodine concentrations. with clusters consisting of: (IA/IsA) 0-4 (W) 0-2 , "Oxides, oxyacid assisted" with clusters consisting of: (IP/IT) 0-2 (W) 0-3 and (IP/IT) 1 (IA/IsA) 1 (W) 0-2 , and "Oxyacids + mix" consisting of: (IA/IsA) 0-2 (base) 0-2 , where base is defined in the computational details, and consisting of (IA/IsA) 1 (SA/MSA/NA/FA) 1 (base) 0-2 . The shaded area corresponds to relative humidities ranging between 34% and 73%.