The small-scale pathway yields 260 milligrams of cyanostar in a 3.6% overall yield over 5 steps. This pathway was optimized to accommodate shorter reaction times such that one can obtain pure cyanostar within 36 hours, if needed. As the foundation of any chemist's joie de vivre, or joy of life, each intermediate is used in the subsequent step without purification. Telescoping the reactions without purification leads to lower yields in the macrocyclization. Fortunately, the purification procedure has been optimized for high recovery of the macrocyclic product. We recommend flash chromatography with a gradient of increasing concentration of CH2Cl2 in hexanes up to 60% CH2Cl2 in hexanes over at least 10 column volumes. Overall, the small-scale pathway would be best to follow to quickly obtain cyanostar in the span of only two days without sacrificing purity.