Successful implementation of electrified technologies envisioned in Sections 3-6 hinges on the ability to coordinate their operation with the power grid. From the viewpoint of an electrified chemical producer, this coordination will allow for valorizing the flexibility of the electrified chemical production by providing various power grid services, thus yielding an additional revenue source. The power grid will also benefit from this coordination to minimize the economic and operational impacts of increased electricity demand from the chemical industry and achieve decarbonization goals (Figure ). Due to the lack of widespread deployment of electrified chemical production technologies, there are limited means for chemical plant owners to realistically evaluate the flexibility and revenue potential of the electrified processes beyond lab-scale prototypes. Thus, it is important to develop high-fidelity yet computationally tractable simulation tools to study plant-to-grid coordination under various technological and regional contexts. In addition, while tools have been developed for select electricity-intensive industrial processes, such as air separations, they have not been generalized to consider a diverse set of unit operations with different functions (e.g., reactions, separations), complex topologies, and multiple products, all of which are features of existing chemical production facilities.