Another scenario involves a flexible molecule with many conformations, where several conformations interact strongly with the protein. Even if the docking scoring function cannot rank the conformations correctly, the docking project can still succeed if one conformation interacts strongly with the protein and has low internal energy according to the scoring function. However, this success might occur for the wrong reason, as the docking conformation may not be a lowenergy, physically occurring conformation. Instead, another truly low-energy, physically existing conformation at room temperature might interact similarly strongly with the protein. Despite the inaccurate rationale, the docking project identifies this drug molecule, and the project is considered successful.