In the end the fabricated electrodes are applied for analysis of cell cultures using impedance spectroscopy. Cell-based impedance studies measure changes in electrical impedance relative to a voltage or current applied to the electrodes covered with cell layer. It uses the principles of electrochemical impedance spectroscopy (EIS) and enables a platform for the recognition of several characteristics of cell cultures corresponding to the metabolism, adhesion, viability, motility and proliferation . We employed a well fashioned device with a planar array of 8 circular ITO electrodes to monitor the state of HepG2 and HeLa cell cultures, during their seeding, attachment to the electrode surface and trypsin induced detachment from the substrate.