The Simplified Molecular Input Line Entry System (SMILES) format is a single-line molecular notation, which has been widely used for handling molecules in a convenient way. The SMILES strings can easily be organized in common spreadsheets and sent by e-mail. However, in combination with NLP network architectures, it provides an easy and convenient way to do deep learning on molecules. Techniques Page 2 of 8 such as data augmentation can improve performance and bring the fidelity of the molecular creation close to 100% .