In this work, by surface chemistry engineering of 2D WS2 monolayers, we innovate a sequencespecific chemical passivation (SSCP) protocoL using 2-furanmethanothiol (FSH, the key had not strongly interacted with the 2D surface. Finally, the sample was immersed in a 0.02M Li-TFSI/Methanol solution for 40 minutes, after which it was air-dried without any additional washing steps. Notably, this stable chemical treatment protocol is developed in benign solvents and can be easily managed in an ambient atmosphere.