DEDs could also fully overcome electron counting limitations by operating at substantially faster readout rates. For example, the readout of pixels in a detector operating at many kilohertz, as is achieved by the 4D Camera, would dramatically reduce CL, but would also produce large volumes of information to be handled ex post facto . Collectively, our experiments indicate that current fast EBEC approaches are sufficient for the determination of accurate ab initio structures by MicroED, with future speed improvements and CL adjustments continuing to reduce CL and improve data quality.