To investigate the shelf-life, the freshly prepared formulations were stored at ambient conditions with the initial precipitate (if any). The samples were collected at day 0, 1, 5 and 30 and quantified by HPLC. The drugs which exhibited very poor loading capacity were excluded from this study. Accordingly, the stability studies of six drugs is presented namely CBZ, CXB, CTZ, CBD, LAP and MT. Previously, we had observed A-pBuOx-A/PTX and A-pPrOzi-A/curcumin exhibited an excellent stability for several months. However, in few cases, POx/POzi based formulation were also found to be less stable .