Having demonstrated the workflow developed here on the two-dimensional case of Alanine Dipeptide, higher dimensional cases are now explored, where visualization of the entire conformation space is not possible and conventional grid-based methods become unfeasible. Sulfadiazine, with a 4-dimensional conformational space, and Candidate XXXII, from the CSP Blind Test , with an 11-dimensional conformational space, serve as a test for the ability of the workflow to handle conformational complexity. Sketch-map 17 is used in these cases to project a 2D representation of the high dimensional perpoint FES for human interpretation.