Informed by the previous visual inspection, we run a further check on the crystal structures: remember that the most of them do not have a second structure to compare for the verification. We further removed CSD structures with atomic overlaps (38) and lone molecules (80, possibly disordered or unrecognized solvent). We also checked for the presence of hydrogen atoms (in certain cases not explicitly included in the crystal structures deposited at the CSD) but given the low impact of hydrogen in the calculation of the internal volume and the weight of the crystal, we did not exclude these 47 defective structures files.