Combustion of carbon-containing fuels to CO2 allows humans to live almost anywhere on Earth and provides power for industrial production. However, as shown in Figure , rapid growth of atmospheric CO2 concentrations has undesired consequences including global warming where the past 40 years have seen temperatures rise at a rate (0.18°C/decade) that is more than twice that (0.08°C/decade) in the 100 years prior. CO2 emissions from naturally pre-existing and anthropogenic activities outweigh uptake and sequestration pathways, resulting in a cumulative buildup of atmospheric CO2 levels. Thus, global warming, atmospheric CO2 levels, and world population are interconnected. Today, our global population is almost 8 billion and atmospheric CO2 levels are ~417 parts per million (ppm). Land use changes and fossil-fuels usage account for ~40 billion metric tons/year CO2 emissions globally as of 2021. In comparison, world population was ~ 2.5 billion in 1950 and the global CO2 emissions were estimated at ~11.5 billion metric tons/year. According to the predictions by an Intergovernmental Panel for Climate Change (IPCC), global warming is likely to reach 1.5°C between 2030 to 2052 (relative to pre-industrial levels between 1850-1900). Due to the far-reaching ecological consequences the international community adopted significant CO2emissions reduction targets ("race to zero" by 2050) in 2015 at the 21 Given these societal challenges and because CO2 is non-toxic, non-flammable, plentiful, and a renewable carbon source, it has been utilized as a sustainable feedstock as part of multi-pronged approaches to decarbonize the atmosphere via capture and biological, chemical, and geological sequestration or storage. Carbon or CO2 Capture and Storage (CCS) technologies are focused on reducing the amounts of CO2 released into the atmosphere by separating it from other gases, compressing, transporting and finally storing the captured CO2 far away from the atmosphere, avoiding any leakage back into the ecosystem. The high costs associated with these technologies have limited large-scale annual capture and storage capacity to only about 0.1% of global CO2 emissions, but this number is predicted to go up to 19% by 2050. CO2 in its purified or impure form (i.e., present in gas mixtures) can be directly utilized as is (enhanced oil recovery, food and beverage industries) or as a raw material for conversion into other substances via geological (carbonates/soda ash, rock and saline formations, minerals, coalbeds, aquifers, etc.), biological (carbohydrates, lipids, proteins, secondary metabolites etc.), and chemical (carbon monoxide, alkanes, alcohols, alkenes, acids, etc.) processes via Carbon or CO2 Capture and Utilization (CCU) technologies. Figure shows the carbon cycle and human contributions to CO2 emissions, and potentially useful technologies for capturing and sequestration of CO2. (red boxes) or capture (green boxes), as number of gigatons (Gt) CO2 per year. In this paper, we present a systematic analysis of the latest trends in CO2 capture and sequestration research utilizing data from the CAS Content Collection of journal and patent publications spanning the years 2001-2021. We focus on technologies capable of reducing global atmospheric CO2 levels. The current global CO2 emissions are at about 40 gigatons/year, therefore a technology should have the potential to sequester gigaton quantities of CO2 each year. We first provide an overview of publication trends by time, country/region, and keywords. Then, the technologies, methods, materials and chemical substances involved in CO2 separation, capture, sequestration and use are discussed and their publication trends analyzed to provide an overview of current developments in CO2 mitigation strategies.