Martini simulations across a wider range of conditions. Another issue pertains to the artificially enhanced dynamics of CG models. Due to the neglect of atomic degrees of freedom, friction is being reduced, leading to a speedup in the overall dynamics . For the new Martini lipidome, we do not expect a much different speedup factor compared to previous lipid models, as seen by similar lipid diffusion constants between Martini 2 and 3 models (Figure ).