Other mechanical property, such as compliance, is also of paramount importance in the context of vascular graft scaffolds. Compliance mismatch has been identified as a key factor contributing to vascular stenosis post-implantation . Comparatively, studies reported mechanical compliance values of native internal mammary arteries at 11.5±3.9%/100 mmHg . Other study employing polylactic-co-glycolic acid (PLGA)-based tubular scaffolds, reported a compliance range of 9-10%/100 mmHg . Following gelatin coating, the fabricated hierarchical structure exhibited an enhanced mechanical compliance of 12%/100 mmHg, underscoring the efficacy of applied coating technique in augmenting tubular structure flexibility for potential applications in vascular tissue engineering. Our engineered vascular grafts demonstrated superior mechanical properties compared to an in vivo study, where the burst pressure of raw tissues was 1275.9 ± 254.0 mm Hg, while our grafts exhibited significantly higher values . Additionally, the Young's modulus for raw tissues was reported at 5.41 ± 1.16 MPa, with increases to 12.28 ± 2.55 MPa in dehydrated samples, whereas our grafts consistently showed higher values. Despite these differences, both our grafts and the in vivo constructs exhibited comparable performance under dynamic conditions. This enhancement underscores the effectiveness of developed coating approach in promoting the compliance, positioning the fabricated hierarchical structure made of PBS-DLS and PBS-DLS-PEG as promising candidates for clinical applications, particularly in light of their adaptability and physiological functionality. However, it's important to acknowledge that scaffolds are intended to undergo complex and extensive in vivo evolution, encompassing processes such as cell infiltration, scaffold degradation, ECM deposition, and more. These progressive changes can substantially alter the scaffold's structure, consequently impacting its mechanical compliance, elasticity, or modulus over time. Therefore, further mechanical evaluations under wet and dynamic condition over longer period of time is required to better understand the mechanical performances of these scaffolds for preclinical researches.