For each of the three motors in Fig , the photoisomerization step was simulated in multiple replicates that represent an ensemble of Franck-Condon points (Section 2.1). As summarized in Table , about 10% of the simulation replicates of Motor S and Motor O progressed to the ground state metastable form. Each of these simulations offers a chemically reasonable realization of photoisomerization. The trajectories are similar to those of other alkene motors in prior works , in the sense that the conformations at which the excited to ground state hops occur are similar, as are the rotational processes. A video of a representative trajectory of Motor S is provided in the ESI (mndo-amber.mp4). Final ground state metastable form conformations of Motor S and Motor O were used as starting conformations for the classical MD simulations detailed in Section 3.3. The starting conformations excluded a few that had not yet relaxed to a sufficiently low-energy conformation and thus were not suitable starting points for the classical simulations. This left 13 and 4 initial conformations for Motors S and O, respectively. For Motor N, the QM simulations did not yield any hops from the excited state to the ground state, despite running for similar durations and numbers of replicates.