Having investigated the aryl Grignard scope, we then turn our attention to exploring the scope of fluoroalkyl halides as radical precursors in this MC-CCR (Scheme 3). Overall, a broad range of di-, tetra-and perfluoro alkyl bromides as radical precursors bearing various functionalities including fluoroalkyl rich (5a and 5b) chains, extended alkyls (5c and 5d), aryl (5e), aryl ethers with relevant functionalities (5fh), heteroaryl (5i), diethoxyalkyl as protected aldehydes (5j), aryl (thio)ethers (5l), and olefins (5m) were compatible in this transformation. Notably, an a,a-difluoro ester bromide engages in the MC-CCR to obtain 5k in acceptable yield (40%). Furthermore, the resulting b-difluoroalkylated compound 5k could be used in the synthesis of fluorinated lactams, 6a an interesting motif for drug discovery. 10 As expected, tertiary alkyl radicals that are hesitant to undergo two-component cross-coupling reactions with Grignard reagents under iron catalysis, were also compatible in this three-component transformation (5n), but a high amount of the nucleophilic addition to C=O bond was also observed (22%). Unfortunately, difluoro alkyl amides failed to give the corresponding product (5o and 5p).