CACHE will also explore mechanisms to provide participants access to a virtual library (VL) containing new chemistry. The concept here is to ask synthetic chemists within academic or industry to contribute to a "New Chemical Space" VL by adding compounds that they would be willing to synthesize "on demand" in a timely manner with their emerging synthetic chemistry protocols, and using their own resources. The purpose of including these compounds is to access structurally unique scaffolds or sub-libraries. This library could serve as a counterpoint to the "parallel synthesis" MoD library and would also provide a mechanism for academic chemists to get their new chemistry screened by a large number of computational methods against a wide range of biologically interesting targets, and in turn for CACHE to sample new and exciting compounds.