Both Isotope labelling and 1 H- N heteronuclear single-quantum correlation (HSQC) experiment were conducted to prove the C-N bond product formation. The results for the aqueous solutions are in good agreement with those reported previously 38 . Both ex situ XRD patterns and in situ XRD were collected with a Malvern PanAlytical Empyrean 3 diffractometer with a Cu K𝛼 radiation source (𝜆 = 1.5418 Å) and a PIXcel 3D detector in 1D mode operated in Bragg Brentano (𝜃 -𝜃) geometry. For a typical ex situ measurement, a range of 5° ≤ 2θ ≤ 80° measured with a PIXcel3Ddetector in 1D mode configuration with iCore and dCore optics with automatic slits set at 10 mm irradiated length and a collection time of 1h.