The number of unique antibody pairs screened in all rNP rounds were 106, 150, 144, and 288, respectively. At the conclusion of each round, we carried over at least the top 20 antibody pairs by signal (average test line signal from positive LFA tests for a given pair) minus noise (average test line signal from negative LFA tests using a pair), or "S-N," and signal divided by noise, or "S/N," given available stocks. Due to the time-dependent commercial availability of the antibodies, we considered Rounds 2 and 3 to be "weed-out" rounds and summarized their results in Figure . We subsequently considered Round 4 as a representative screen of the best-available-at-the-time antibodies against AB-rNP, in preference to Rounds 2 and 3.