[Ube13]). As such, we cannot conclude if these targets may play an important role in thrombosis or viral infection/reactivation risk and are limited in the conclusions we can draw. Thus, we encourage researchers with access to the appropriate assays to validate these targets. Moreover, there might be additional targets of relevance that were not predicted by our computational tools. We also acknowledge that the activity of small molecule drugs using in vitro assays does not always translate into activity in the cellular environment. Thus, the results should still be interpreted with caution and treated as preliminary evidence for the off-target binding of baricitinib and tofacitinib.