Single-atom catalysts (SACs) have emerged as a revolutionary strategy to address the sluggish kinetics of the oxygen evolution reaction (OER) . By dispersing individual metal atoms on a support matrix, SACs maximize atomic utilization and create highly active sites with welldefined electronic environments. These isolated metal atoms often exhibit unique catalytic properties due to their unsaturated coordination and strong interaction with the support material, which tunes their electronic structure for optimal binding of OER intermediates such as *OH, *O, and *OOH. This precise control of binding energies minimizes overpotential by addressing the Sabatier principle, thereby enhancing catalytic efficiency.