Level 2 ("two-dimensional evaluation") requires additional information from calculated or simulated data to be used for comparisons. Typical examples are consistency checks with calculated data or plausibility checks using simulated data. In both cases, the information obtained from data files and analyses is compared to theoretical information gained from the chemical structure (Figure ). To test the plausibility, the information obtained from the data files in the form of data points or signals is compared with the simulated data points or signals and evaluated while considering the tolerances specific to the data type. In this work, NMR and IR data are utilised for a plausibility analysis (see descriptions in the section plausibility). The consistency of the data is reviewed by comparing the data files or the data analyses with calculations that are available based on the chemical structure. Methods for NMR and mass data can be proposed to confirm the consistency of the data (see descriptions in the section consistency).