The absorption in NIR wavelength region suggests that the TN-loaded nanogels may possess powerful photothermal conversion capability. Therefore, the photothermal conversion effects of various nanogels were systematically investigated with a real-time infrared thermal imaging camera (Figure ). Under continuous 808 nm laser irradiation (0.6 W cm -2 ), the temperature of P-TN nanogels could elevate rapidly and go up to 62.0 o C after 15 min, while the temperatures of TN-free solution (water and PNA nanogels) showed no significant change.