The molecules used in this test and their division are illustrated in Scheme 2, with simulation results shown in of the all-atom (AA) model with a satisfying accuracy, indicating that the EX2-rematch method can accurately handle the Lennard-Jones (LJ) interactions for CG particles with relatively low resolution. However, the properties of some ring molecules, such as pyridine (PRD) and pyrrole (PRL), are significantly overestimated or underestimated across all temperatures. This discrepancy arises from errors in the electrostatic interaction between atoms groups within these molecules. These errors primarily stem from the numerical summation charge method, which made incorrect estimation of electrostatic effects in low-resolution CG models, especially for heterocyclic systems.