STRINGdb analyzed the set of FMC-related proteins and displayed connections between them based on their relationship to one another. Colored nodes mean query proteins and first shell of interactors; filled nodes mean that 3D structure is known or predicted; empty nodes are those proteins of unknown 3D structure. Edges are drawn with up to seven differently colored lines, which represent the existence of the seven types of evidence used in predicting the associations: red line indicates the presence of fusion evidence; green line-neighborhood evidence; blue line-cooccurrence evidence; purple line-experimental evidence; yellow line-text-mining evidence; light-blue line-database evidence; black line-co-expression evidence. (A) Network based on proteins corresponding to the genes in Table . (B) Enriched network with CBL, GRB2, NOTCH1, PDGFRB, and TEK proteins added (notified with the red asterisks).