Metabolomics (including lipidomics, also known as metabolic phenotyping) is a powerful bioanalytical approach employed for the purposes of biomarker discovery in clinical and population-scale research. Metabolomics studies are characterised by the inclusive measurement of the dynamic and versatile human metabolome(s) providing insight to physiological and pathological processes at a chemical level. This kind of measurement is enabled by a combination of specially adapted bioanalytical technologies, fit for purpose methods and protocols, and accompanying bioinformatic and chemometric tools for data extraction, pre-processing and interpretation. When used together, these resources constitute a platform for metabolomics.