We also added support for the new DrugEx features to our GenUI platform, which provides a graphical user interface (GUI) for molecular generators. GenUI is an open-source web-based application built with the Django web framework 25 and the RDKit cheminformatics toolkit. GenUI provides features for easy integration of cheminformatics tasks commonly used in de novo generation of molecules (i.e. management of a compound database, QSAR modelling and chemical space visualization). As of now most of the features available through the DrugEx Python package are also exposed in this GUI to allow quick creation and management of generative workflows from the import of the training data to interactive visual analysis of the generated and real chemical space. One notable feature of the new GUI is the interactive creation of scoring environments, which makes the setup of desirability modifier functions for the multi-objective optimization more intuitive (Figure ).