ART is rapidly evolving, with research focused on improving safety, success rates, and accessibility. Future trends involve: (i) tailoring treatments to individual genetic profiles through personalized medicine approach; (ii) improving embryo selection and predicting outcomes via AI integration and automation; (iii) expanded accessibility by developing lower-cost methods to reach underserved populations; as well as (iv) exploring the long-term health of ART-conceived children and refining techniques like artificial gametes.