The degree of amorphization after AMF exposure of the tablets was quantified by XRD and DSC. Figure shows the XRD diffractograms of tablet 26 as prepared and after 3 and 15 minutes of AMF exposure. The as prepared tablet displays the characteristic diffraction peaks of crystalline celecoxib. The intensity of the crystalline peaks diminished already after three minutes of AMF exposure. Complete amorphization was achieved after 15 minutes, as indicated by the "halo" characteristic of an amorphous material. Similarly, the depressed melting endotherm of crystalline celecoxib in the presence of PVP at about 140 °C in the as-prepared tablets was no longer detected by DSC after AMF exposure (Figure ). The successful amorphization is evident in the DSC thermograms from a single glass transition (Tg) of the polymer after in situ amorphization (Figure ).