With the alteration of weaving patterns, we anticipate that the space field (Box 1a) between the warp and weft strands will also be affected. Changes in the space field can not only reflect the flexibility of the weaves but also determine the ability of the molecular fabric to function as a net. Consequently, we analyze the pore size distribution (PSD, Box 1b) using PoreBlazer to assess the degree of deformation between the IS and ES (Fig. ). Initially, all three weaving models exhibit similar pore distributions, characterized by three distinct peaks at 0.7, 2.4, and 2.6 nm, suggesting the similarity between their initial models. Upon reaching equilibrium, the plain weave demonstrates the least variation in the space field, evident from the presence of two peaks at 2.7 and 2.8 nm. This outcome suggests that the highest entanglement density in the plain weave imposes the most substantial constraint on the reptation of the strands, thereby preserving a relatively regular pore structure. In contrast, the absence of the primary peak and the appearance of a wide range of distribution of pores with various sizes are observed in both mix (2~3 nm) and basket weaves (1.5~3.5 nm), indicating considerable structural deformations. To provide a clearer understanding of the structural information contributing to the varying kinetic stability of the three weaves, the first-principles calculation in CP2K package was carried out to optimize one of the repeating grids in three weaves. In the plain weave, three types of weft-wrap interactions were observed including the edge-to-face and face-to-face π-π interactions between aromatic TTZ units on weft and warp strands, and C-H•••N hydrogen bonding between methyl hydrogen and the nitrogen atom on the benzimidazolylpyridyl unit (Fig. ). Calculations reveal that the face-to-face configuration has a 4.8 kcal/mol lower interaction energy compared to the edgeto-face configuration and the hydrogen-bond contributes ~3.4 kcal/mol interaction energy. Despite three weaves consist identical chemical composition, the change of weaving patterns varies both the type and strength of the interstrand interactions. Elaborately, while no discernible aromatic stacking alterations are observed in the mixed weave, there is a significant reduction in hydrogen bonding (5 pairs in plain weave vs. 1 pair in mixed weave), resulting in lower stability than that of the plain weave (Fig. ). Additionally, in the basket weave, we observe fewer face-to-face conformations (2 sets in both plain and mixed weaves vs. 1 set in basket weave), along with the absence of hydrogen bonding interactions within the grid, indicating the lowest stability (Fig. ). The simulation unequivocally illustrates the pivotal role of interstrand weak interactions in stabilizing the weave, ensuring the strands retain their association within the material's pattern. Moreover, the strength of the weft-wrap interactions is directly correlated with the weaving pattern.