Based on the advantages of SACs, we propose an iron-nitrogen doped carbon-based SAC for catalytic oxidation of formaldehyde. Carbon materials such as graphene are good catalyst carriers given their large specific surface areas and have the ability to form strong interactions with metal atoms and high thermal conductivity. Moreover, single vacancy and double vacancies at carbon materials act as doping sites for active centers. Metal atoms can be anchored on the carbon lattice by bonding with nitrogen atoms inserted into vacancy defects of carbon materials to anchor iron atoms more firmly. At present, iron-nitrogen doped carbon-based SACs have been synthesized and their performance has been tested in the laboratory. Two iron-nitrogen embedded carbon materials for catalysts (FeN3 and FeN4) exhibited high catalytic activity towards oxygen reduction reaction (ORR). However, there are few reports devoted to the removal of formaldehyde by SACs at room temperature.