The most pronounced impedance reduction due to cell growth was seen at 5 Hz and is highlighted in Figure . In this study we observed a reduction in impedance in both UVO treated pDPP3T films over time, which could possibly be explained by diffusion of ionic media into the film whilst biasing, which is well known in CPs independent of their chemical composition. By comparison of the datasets, it is observed that the presence of SCL4.1/F7 Schwann cells grown on the surface have an insulating effect, causing an increase in the lowering impedance, as is typical of bioimpedance measurements of materials with cell coverage. Yet, these results demonstrate the ability of UVO treated pDPP3T films to support interfacial cell growth whilst maintaining electroactivity. The intricacy in cell mediated processes at the electrode-electrolyte interface will vary with each selected matrix and CP substrate, the future study of which is enabled by the UVO technique that provides a facile method to augment the biocompatibility of semiconducting polymers. 32