Two organic reactions carried out through mechanochemical synthesis were explored (Figure ), using our T1-T2* 1 H-NMR measurement. This technique allows for easy analysis with minimal workup. Both reactions use o-phenylenediamine as a reactant, and derivatives of benzil. First, the well-known reaction of benzil and o-phenylenediamine (pathway i) to make 2,3-diphenylquinoxaline (1) was explored. The reagents are inexpensive and easy to obtain. This was beneficial for the T1-T2* relaxation time measurements because of the large quantity of sample needed to obtain good signal. The reaction yielded 99% with dry milling. Second, 4,4'-dimethylbenzil and o-phenylenediamine were milled via LAG with acetonitrile to form 2,3-di-p-tolyl-quinoxaline (2). Pathway ii followed similar procedures to pathway i. The addition of acetonitrile was needed to achieve reaction completion, with a yield of 96%. The yields for both reaction pathways are similar to other green and traditional synthesis methods reported. The benefit to the mechanochemical reaction is heating, solvents, catalysts and purifications are avoided. Both products were characterized by PXRD and 1 H-NMR spectroscopy (supporting information, Figures S27-S28 and S30-S31), compound 2 was characterized through single x-ray crystallography (supporting information S7). Reaction yields were calculated using 1 H NMR spectroscopy since there was no purification of the products.