Next, the value of the acquisition function was visualized to see which experiment would be performed next with the highest priority from the EDBO algorithm identify critical factors (T3), as shown in Figure . The highest values for the acquisition function were using the latest discovered optimal ligand (CgMe-PPh) and the previous best solvent/base combination: DMAc/KOAc. In these experiments, only the temperature and concentration would be varied, therefore the chemists decided to take a sample of experiments from this area using temperatures and concentrations combinations that were not yet studied on these conditions (e.g., a low temperature and high concentration). For the remaining experiments, the chemists stated they would decide between exploring other ligands that had not yet been explored or changing the base and solvent with the best current ligand.