For a given material, we plot λ1500 vs. the minimum activation energy min(E A ) and color-coded by the average of all paths, ĒA . As expected, a small min(E A ) is a necessary but insufficient criteria for a large diffusivity, as up to 8 orders of magnitude change in diffusivity can be observed for materials with min(E A ) < 0.5 eV. This indicates the importance of a screening model that can estimate activation energies of all possible (including high E A ) paths in a structure as well. Figure shows an Arrhenius plot of diffusivity and the orders of magnitude change among different materials and across temperatures, some of which deviate from Arrhenius behavior in the modeled temperature range. Figure 4e reveals that most materials have near-isotropic diffusivities, but some can have λ max T as much as 8 orders of magnitude greater than λ min T ; furthermore, among those with the highest mean diffusivities (e.g., > 10 -6 cm 2 /s), a higher percentage of materials tend also to have large λ aniso T . This anisotropy is also highly temperature dependent, i.e., some materials that are isotropic at high temperature become highly anisotropic at lower temperatures (Figure ).