The progress in anti-aging research has shown the potential to improve health and quality of life for older adults by promoting healthy aging and delaying the onset of age-related diseases. In pursuing a solution to the aging issues, it is necessary to keep clear in mind that the goal of research on aging hallmarks and anti-aging strategies is not to enhance human longevity, but to enhance healthy, active longevity, free from disability and functional incapacity. Such understanding of aging has resulted in a shift in the approach for aging interventions from anti-aging to healthy aging. In order to achieve healthy aging, it would be appropriate to abandon disease-oriented research approach and adopt health-oriented prevention strategies.