The graph shows that the temperature of the drug-protein complex fluctuates over time. This is because the particles in the drug-protein complex are constantly moving and colliding with each other The graph shows that the bond energy of the drug-protein complex decreases over time. This indicates that the drug-protein complex is becoming more stable over time. This could be due to a number of factors, such as the formation of hydrogen bonds or the packing of the drug-protein complex into a more compact structure.