By using the SQLite database format, filtering is very fast. In our tests it takes just over 4 minutes (252 seconds) to filter by a simple energy cutoff with the reference library of over 2 million ligands on our testing hardware. Filtering by hydrogen bonds with a single residue similarly takes under 4 minutes (228 seconds). An energy percentile filter takes about 8 minutes (466 seconds). Given the disk-based storage solution of SQLite, faster hardware (i.e.: SSD and NVME drives) are expected to reduce significantly filtering times.