During the course of synthesis of nitrofuranyl derivatives described herein using the already established procedures, highly impure and polymeric samples were obtained. To this end, and in line with the previously reported reactivity of nitrofuranyl derivatives, in particular, 5-nitrofurfural in alkaline media, herein this work offers a versatile and high yielding new synthetic procedure for synthesis of nitrofuranyl derivatives which has potential to be extended to a large array of similar unstable heterocycles in protic solvents. Furthermore, 1 H together with 13 C NMR analysis shed light on the nature of some of the resulting products of the aforementioned side reactions, all of which differ in appearance, in particular, their intrinsic colours to that of the desired products. Inasmuch as the much remarked erroneous physical properties of 1 in the literature, in particular, its intrinsic colour had been overlooked for more than half a century, due, in part, to the highly impure samples of 1 elsewhere, it compelled the author to lay a secure foundation of sound theory of observable phenomena in question for the outsider such that considerable detail had to be given in parts of this manuscript which are concerned with the intrinsic colour of nitrofuranyl derivatives, and may, though it need not of necessity, be of interests to the synthetic and medicinal chemist when occasion demands.