In the present article we investigate the results of an interplay between hydrogen migration, hydrogen scrambling and loss of multiple neutral fragments in the dication of the smallest polyene, 1,3-butadiene, in its most stable entgegen E form . These dications were formed by the collisional interaction of 810 keV Xe 3+ ions with neutral molecules of 1,3-butadiene. The fragmentation products resulting from an isolated dissociating dication were detected together in coincidence using a time-offlight mass spectrometer. The butadiene molecular dication formed with high internal energy and left to itself, devoid of any surroundings, is capable of emitting multiple neutral particles (H/H 2 /C 2 H 2 ) leading to formation of several daughter dications having different masses. Although, the emission of a single neutral particle (H/H 2 ) as a means of releasing internal energy stored in a molecular ion has been reported in literature for many small aliphatic hydrocarbon molecules , reports on loss of multiple neutral fragments from such ions are rare and not discussed.