Biosensors are expecting to play a pivotal role in the future of healthcare, enabling personalized therapies, effective chronic disease management, early diagnostics and point-of-care monitoring. Due to unique features, such as selectivity and specificity, enzymes are particularly attractive bioreceptors in such systems, , and their use, along with an electrochemical-based transduction, enables the development of miniaturized and simple-to-use devices . In enzyme-based electrochemical sensors, the effective electron transfer between the redox center of the enzyme and the electrode is key. As a direct electron transfer between enzyme and electrode may be challenging, and highly depending on the enzyme used, the use of redox mediators to facilitate the electron transfer can prove to be more effective. To date, a series of approaches have been developed to immobilize enzymes at transducer surfaces while achieving efficient electron transfer processes. Nanomaterials with continuous nano-networks are promising candidates, such as graphene, carbon nanotubes (CNTs) and metal oxides. However, the electrode fabrication processes are in-efficient, which often adopt 'bottom-top' approaches, leading to time-consuming synthetic and doping steps for the bioelectrodes. In addition, health effects about employing these nanomaterials have been reported, in particular, the biocompatibility and the carcinogenicity of CNTs. Therefore, there is a need for the development of new nanomaterials for bioelectrode fabrication.