The impact of base stabilization on sulfate aerosol formation is well established, with synergistic effects between a mixture of different bases promoting nucleation to a greater extent than a single base. For example, amines encourage proton transfer reactions and have a larger stabilization effect on smaller clusters while ammonia's smaller size makes it the ideal candidate for encouraging growth by maximizing the total number of hydrogen bonds between cluster constituents. Based on pKa and gas phase proton affinity, glycine is a slightly stronger base than ammonia while also simultaneously being capable of forming more intermolecular interactions than amines such as methylamine and dimethylamine. Under the premise of the principle of microscopic reversibility, fragmentation pathways are the reverse of the formation pathways. Irrespective of whether the mixed clusters were activated on a millisecond timescale (CID) or by a few nanosecond long infrared pulse (IRMPD), the dissociation pathways were always the loss of ammonia or the loss of ammonia and sulfuric acid. This implies that glycine is more strongly bound within the cluster. It is, however, apparent that if present together, glycine will compete with ammonia to bind to sulfuric acid. Given that a small concentration of glycine (compared to ammonia and sulfuric acid) is adequate to facilitate extensive cluster formation among the three components, it's plausible to consider that a replacement of ammonia by glycine might be a part of the aging process of new particles