Having numerically predicted the thermostability of the various motifs, we constructed different condensates using the designed X-motifs described above on an isothermal condition instead of a thermal annealing method comprised of multiple thermal gradients. The solutions were incubated for more than 1 h at a fixed temperature of 25°C (See Supporting Information for further details). Across all the designed motifs, robust formation of gel structures displaying sponge-like structure was observed at 25°C (Figure ).