Dawar et al. stated that the application of agrotain treated urea showed a significant reduction of urea hydrolysis within the first 7 days of application as compared to control, which showed the almost complete hydrolysis of urea within the first 2 days of application. It is estimated that the utilization of nitrification (nitrapyrin) and urease inhibitors could significantly reduce the annual reduction of about 15-50% N2O emission in rice and wheat field, followed by more than 50% NH3 volatilization reduction . Ni et al. reported that the combination of urease and nitrification inhibitor (DCD and 2-NPT) significantly reduced the production of 98.12 mg N/m 2 ammonia within 0-19 days observation.