Another potential limitation in the simulation may come down to the actual equilibrium moisture content compared with the degree of acetylation. Hunt et al. has previously developed a correlation between moisture content and acetylation, identifying a reduced water content with increasing acetylation. While we replicate the overall trend, with the equilibrium moisture content falling by approximately 10% in dry weight terms between unacetylated and fully acetylated wood, from 20% to 10% in experiment meant to replicate forest products that have begun their path down the value chain, and from 30% to 20% in our simulation model that reflects newly cut wood (Fig. ). Thus, while we replace the same amount of water with acetyl groups in the constant system as is relevant to experiment, we would anticipate that the even lower hydration levels observed in experimental wood samples would further reduce diffusion below what we report here.