MD simulations revealed that the peptides change their starting configuration and form different backbone turns, defined by the proximity of the Cα atoms of residues i and i+3 (cutoff distance ≤ 7Å). It was found that the populations of some of the turns correlate well with the hemolytic activity (Table , Supporting Information). Noticeably, the high mobility of all Disomers (8a, 8c) leads to a nearly uniform population of most of the turn populations.