Reaction records from the United States Patent and Trademark Office (USPTO) were collected from the ORD, sharded across 489 datasets. The link to a complete list of dataset IDs can be found in the Supporting Information. These records were originally published by Lowe in Chemical Markup Language (CML) format and were imported into the ORD using a custom CML-to-ORD translation script. A reaction record is admitted to our dataset if it satisfies the following conditions: