To examine the above idea, the PDPS refinement was performed. . The frequency shift of the H-O bond from 3160 to 3445 cm -1 (Figure )for the DMSO and to 3497 cm -1 (Figure ) for the THF is reciprocal to the relative polarity of the solute (THF 0.207 vs. DMSO 0.444). The higher polarity of the DMSO polarizes more hydrating H2O dipoles that screen the DMSO field compared with the THF.