There is a vast diversity of molecules presenting potential interest as the subject of metabolomic analyses. Due to the different nature of their chemical properties, it is unfeasible to explore their behaviours in biological systems except when using a panel of complementary separation and detection techniques. Each analytical platform shall be able to grasp the most relevant information about one of more families of chemically-related compounds. In the case of capillary zone electrophoresis (CZE), the mechanism driving the separation makes it particularly well suited for the analysis of polar and charged molecules . Even though a significant fraction of the most commonly studied metabolites falls within this category, the use of CE still remains quite limited in the field of metabolomics .