Within this mild temperature range, BNNS-Arg@Lac showcased the highest enzyme activity, underscoring its adaptability to natural conditions. In line with previous studies, 37 nlaccase peaked in activity at 50 °C, but it is not an environmentally relevant condition. The enhanced stability in the face of changing natural conditions can likely be attributed to the interaction between laccase and arginine on BNNS. Many studies indicate that the covalent modification of enzymes with small molecules, such as natural amino acids, can bolster their stability. Thus, arginine might not only aid in the synthesis of the supporting material, BNNS, but also enhance the stability of the immobilized enzymes.