PubChemLite has been used in several NTS applications; user feedback helps ensure the relevance for environmental screening. Collaborative research activities have already identified less relevant content (as described above), but also poor coverage (possible lack of annotation content) for compounds in sediments. The chemical stripe integration helps researchers visualize and interpret the chemical history over time , while the annotation summary pages display basic information available simply, providing direct access to PubChem for the full content. The predicted CCS values will help improve NTS workflows for IMS, while the growth of the experimental CCS dataset will help predictive models such as CCSbase improve accuracy and relevance over time. PubChemLite is openly available () -feedback is welcome (see contact page).