Previous work has explored the steps of upcycling and modeled its implementation at smaller scales. Our analysis demonstrates that the chemical upcycling of waste plastics is economically viable on the scale of the entire continental US, while enabling a significant degree of circularity with regard to plastic waste production. Though processing costs of upcycling exceed those of existing methods, the value of its products are also correspondingly much greater. Furthermore, upcycling compares favorably with existing waste management systems, presenting significant reductions in land use (relative to landfills) and GHG emissions (relative to incineration or waste-to-energy). Now that a basic economic picture of upcycling on the national scale has been established, future work could explore some of the simplifying assumptions of our analysis. Our infrastructure design represents the potential of upcycling for residential waste plastic: even though the US already has a limited network of facilities such as MRFs, the arrangement of technologies in this study includes no existing facilities, which allows for simplifications in our analysis. Incorporation of these existing facilities could change minute details of the product transportation and facility placement patterns we observe, but is unlikely to impact our overall conclusion on the viability of this national system. Furthermore, the economic value created by the chemical reformation of polymers completely covers the capital costs of this potential network, so if existing facilities were included, total required investments would decrease, which could increase the value that propagates back to residential waste providers. However, we assume that model MRFs, with cost and yield factors based off of existing facilities, are able to sort all mixed plastic wastes, which may be beyond the capabilities of certain existing US MRFs.