The physicochemical properties and eventual practical use of MOFs are closely tied to their morphology. The morphological features depend on the experimental parameters such as synthesis temperature, time, and the stoichiometry of the reagents. Rapid, eco-friendly, and scalable synthesis of MOFs is needed to advance the practical implementation. The use of supercritical fluids (SCFs) as synthesis environments is a promising approach due to the tunable properties of supercritical fluids and their non-toxic nature. The SCFs exhibit gaseous-and liquid-like properties, enabling efficient mixing of the organic compound for various applications , including the synthesis of several material types. In particular, scCO2 has attracted considerable interest since the synthesis requires low energy consumption (Tcr = 304.1°K, Pcr = 7.38MPa) and its antisolvent properties that can enable reusing the solvents and, in turn, reducing the amount of waste stream. One of the challenges facing the practical application of MOFs is the lack of scalability of the laboratory methods used for their discovery, making it challenging to translate the process from the laboratory to an industrially viable process. Shifting from the batch process to continuous flow reactors could be a promising scale-up path ; however, preserving the quality of MOFs in the high-throughput synthesis can present a challenge. Rasmussen et al. demonstrated the feasibility of producing high-quality HKUST-1 and UIO-66 MOFs in a continuous flow scCO2 reactor. Their findings indicate in the single-phase conditions are met, the scCO2 environment eliminates the diffusion limitations of reactions in liquid media and multiphase flows, allowing the synthesis of HKUST-1 within a short residence time (res = 70 -170 sec). However, the authors did not investigate the extended range of synthesis temperatures or shorter res. Among the unanswered question are (i) what is the limiting operating envelope for HKUST-1 MOF synthesis, and (ii) are there optimal conditions for the production of MOF? This letter reports the impact of synthesis temperature by systematically varying the scCO2 injection temperature in a sub-second residence time reactor.