When using ChemDASH with a system containing open-shell transition metal cations, we must carefully consider how we define magnetism in an evolving system. This is important for magnetic spinels as the energy of the system is directly dependent on the magnetic structure. ChemDASH uses the ASE python module to define the crystal and magnetic structures and as implemented, each magnetic moment is fixed to each atom object in the system. In many crystal structures however, a swapping of atoms across crystallographic sites does not affect the magnetic structure. This is well described in spinel systems where the Néel magnetic structure (where magnetic moments in tetrahedral and octahedral sites are aligned anti-parallel to one another as shown in Figure ) is found in many magnetic spinel systems over a range of degrees of inversion. Therefore, in this work, each magnetic moment is treated to be fixed to their initial crystallographic sites rather than the atom objects which occupy those sites. The magnitude of each magnetic moment is initially set to ±5 µB (depending on site) and allowed to relax to a local energy minimum in VASP. The end members in the Zn-Mn-Fe-O system have varying magnetic structures due to the nonmagnetic d 10 Zn atoms.