microcompartments as well as providing ribosome synthesis, signal transduction, stress regulation, transcriptional noise buffering, or nuclear heterochromatin area production functions. One important component of membraneless organelles are intrinsically disordered proteins (IDPs), which do not have a fixed, ordered 3D structure, unlike typically "ordered" proteins, likely due to repulsion of like-charged residues. Due to a lack of 3D structure, IDPs have high plasticity, i.e., they fluctuate between multiple conformations instead of folding into a single well-defined 3D structure. However, IDPs can attain a fixed conformation when they bind with each other or with RNA/DNA, potentially forming stable membraneless organelles. IDPs all contain low complexity (LC) domains, and it is believed that LC domains are the main drivers in biological phase separation, as they are frequently concentrated in membraneless organelles.