The SG rules derived in this study are expected to describe outstanding materials whose performance is governed by the same processes governing the reactivity of the exceptional materials in the input data sets used for training. The analysis of four-and five-component materials was focused, nevertheless, on low ruthenium contents and on V Ç and V ^ elements compatible with tungsten, i.e., with similar atomic radii. Thus, it is unclear if the SG rules presented in Fig. can identify exceptional materials and conditions for any arbitrary ruthenium content or for V Ç and V ^ elements which have significantly different radii compared to tungsten. This is because different mechanisms may operate on these materials which could also lead to exceptional performance. Therefore, the SGD analysis might need to be performed including new data points covering such so-far unexplored portions of the materials space for enlarging the domain in which the SG rules can detect exceptional catalysts and reaction conditions.