The initial guesses of ΔΔ𝐺 ‡ solv (298 K) and ΔΔ𝐻 ‡ solv (298 K) are arbitrarily set to -1 kcal/mol and -1.5 kcal/mol, respectively, while the initial guesses of the Arrhenius parameters, 𝐴 and 𝐸 𝑎 , are determined based on the experimental data. To find the best initial guesses for 𝐴 and 𝐸 𝑎 , the ln 𝑘 vs 1∕𝑇 plot is first made using the experimental data, and a linear line is fitted only using the data points at a lower temperature region (around 𝑇 < 0.75𝑇 c ) where the Arrhenius behavior is observed. Then the fitted linear line is vertically shifted to match the experimental ln 𝑘 values near 𝑇 c .