Figure shows the FES calculated for fiber (2) (analogous ones for fibers (1) and (3) are reported in Supporting Figure ). From the FES it is evident that all micro-states lie within 2 kcal/mol of free-energy. The rather flat free-energy landscape explains, retrospectively, why this system can be efficiently sampled via an unbiased CG-MD simulation, and why fiber (2) is so rich and heterogeneous in terms of monomer states. By connecting the micro-states of Figure with arrows and adding the exchange probabilities (in white) obtained from the matrices in Figure , we are able to provide a complete kinetic map for the internal structure and dynamics of fiber (2). This annotated map provides a concise description of the internal structural and dynamic diversity of the supramolecular polymer. Such a detailed characterization sheds new light on the complexity of such supramolecular polymers. This makes it easier to answer questions about the nature of defects and the structural and kinetic relations between them. By using metadynamics simulations, we recently demonstrated that fiber (2) predominantly exchanges with the external solution monomers that are just absorbed onto the surface and not stacked/incorporated onto the fiber core. These are the monomers labeled in red (or orange) in this analysis, which constitute, in fact, the monomer state having the highest free energy among all others. These absorbed monomers may be produced from the interior of fiber (2) following a variety of pathways that have a blue or yellow defective state as intermediate.