It is noted that the idealised trapezoid geometry used in this model is not necessarily suited to alternative heteroleptic MOC architectures. Rather than provide a generic system for expansive exploration of chemical space, this approach was intended to be used for expediting the successful realisation of targeted metal-organic systemsin this instance, cis-Pd2L2L'2 cages specifically. It is anticipated that the core concepts, however, could be adapted to provide similar, rapid geometric analysis for alternative system designs.