In combination with closed-loop high-throughput experimentation, this would allow for fast access to data that cover the problem space adequately and thereby enable optimal modelling. Current challenges for automation pipelines include the purification and analysis of the reaction outcome , which is particularly challenging in asymmetric organocatalysis. Due to its relevance for industrial processes however, we expect an increased interest in HTE platforms specifically tailored to organocatalysis, especially (organo-) photocatalysis . With ML tools becoming increasingly accessible for non-experts through easy-to-use interfaces , their application is expected to gain greater popularity and be integrated into existing routines .