The lipid POPC PBd-PEO polymers were blended into mixtures to form hybrid GUVs. As polymer molecular weight is thought to control the membrane thickness and therefore the membrane's bulk properties, PBd-PEO polymers of two different sizes (PBd22-PEO14 or PBd12-PEO11) were compared. Hybrid vesicles were formed with well-mixed and homogenous with a monomodal but broad composition distribution between individual GUVs. No evidence for lipid-rich or polymer-rich microscopic membrane domains was observed. The homogeneity and mixing of these hybrid GUV membranes was also supported by Laurdan GP measurements, which showed comparable hydration states between the lipid-only and polymer-only GUV compositions. This provides further support for the apparent compatibility of PBd-PEO polymers with fluid phase phospholipids like POPC.