Medicinal plants find their applications in the manufacture of herbal medicines since it is proven to be a safer alternative to commercially available medicines. Research and analysis on a group of plants have been done for their medicinal properties, out of which Nigella sativa has emerged to be a herb with rich historical and traditional backgrounds. Nigella sativa (N. sativa) which is cultivated in different parts of the world has been used as a remedy to treat several diseases. The seeds of this plant consist of proteins, carbohydrates, crude fibres, alkaloids, saponins, ash, fixed oils and essential oils. . The pH of N.sativa seeds is around 5.6 to 5.7 or sometimes slightly lower than that which indicates its slightly acidic. Reports have been generated on several activities of this plant, which include antioxidant and anti-inflammatory agents and furthermore used as an antihypertensive and anti-microbial agent. Studies on N. sativa has led to the discovery of a wide array of its pharmacological activity by multiple researchers. The seeds consist of fixed and essential oils, saponins, alkaloids and proteins, the antimicrobial activity is due to the presence of a component called Thymoquinone. The oil assists in decreasing blood pressure and increasing respiration. Rats treated with the seed extract for a period of 12 weeks showed signs of reduction in triglycerides, cholesterol and glucose. Use of either the seed extract or its oil has no impact on liver or kidney functions in the human body.