Next, for Goal #2 Betinol et al. tested a model designed for secondary amine catalyzed reactions, and demonstrated the transferability of their model to new reactions with more complicated conditions that were not represented in their training set. With both models successfully extrapolated to more complex reactions, Betinol et al. moved on to goals #3 and #4. Selecting the optimal catalyst for a given reaction (Goal #3) was tested on the asymmetric epoxidation of cinnamaldehyde, while selecting the optimal catalyst to synthesize a product (Goal #4) was evaluated on the synthesis of diols via two different pathways. The results of both studies were highly encouraging, with predictions being within 1 %ee of experimental results.