In a similar vein as the datasets, the descriptors that were added are a selection of descriptors that we frequently use. We believe that the provided set will be sufficient for anyone investigating a specific protein (family), and that high quality results can be obtained. However, we understand the need to tinker with all options of the process, and we separated the descriptors from the main dataset instead of adding them together. This gives the option for researchers to implement their own descriptors if so desired, while keeping the format of the original Papyrus dataset.