Oxindole-based molecular motors are a class of synthetic nanomachines that utilize the unique photochemical properties of the oxindole scaffold to achieve controlled, unidirectional rotation at the molecular level. The oxindole core offers inherent chirality and can be easily functionalized, making it a versatile platform for developing molecular motors with tunable properties. Recent research has demonstrated that substituent modifications on the oxindole structure can significantly influence the absorption characteristics and quantum yields of these motors, thereby enhancing their efficiency and expanding their potential applications in fields like responsive materials and nanotechnology. The photoisomerisation of oxindole photoswitches has attracted attention due to their ability to perform a 360 • twist by absorbing two photons. In Figure , the potential energy surface interpolating the two S 0 /S 1 CXs, connecting the 0 • and 180 • minimal structures. The two S 0 /S 1 CX structures appear at approximately 47 • and 121 • twisting. A comparison with all-electron SF-TDDF and MRSF-TDDFT is added as reference on the same interpolated geometries. Overall, the relative energies as well as the topology of the potential energy surfaces are in very good agreement. The ground state average difference between MRSF-TDDFT and SF-TDDFT is 1.20 kcal/mol, with a standard deviation of 1.81 kcal/mol. For the excited state it is 0.59 kcal/mol with a standard deviation of 1.53 kcal/mol. The main changes come at the the CX. At the 47 • conical intersection, MRSF-TDDFT has an energy gap of 10.14 kcal/mol, whereas at the conical intersection of 121 • , MRSF-TDDFT features a gap of 5.33 kcal/mol. With respect to the 0 • isomer, the 180 • form is respectively 0.33 kcal/mol (SF-TDDFTB) and 1.01 kcal/mol (MRSF-TDDFT) less stable.