Here, we report the synthesis of perfluorocycloparaphenylenes (PFCPPs), a class of highly strained ring-shaped perfluoroarenes (Fig. , bottom) in which all hydrogen atoms of the corresponding cycloparaphenylenes (CPPs) are replaced with fluorine atoms. This replacement of hydrogen with fluorine can be expected to result in a significant change of the structural and electronic properties of the PFCPPs 20 . Two major methods for the synthesis of CPPs have been reported: (i) converting C6 units, such as cyclohexane and cyclohexadiene, of macrocyclic precursors into benzene rings , and (ii) reductive elimination from macrocyclic metal-arene complexes (metal = Pt, Ni, Au) . However, even partially fluorinated CPPs (F8 [6]CPP, F12 [9]CPP, F8 [12]CPP, F4 [10]CPP, F4 [12]CPP) synthesized by the groups of Yamago and Jasti require multiple steps (method (i), Fig. ), and there has no successful synthesis of CPP derivatives from ortho-functionalized aryl groups by the Pt method . We hypothesized that PFCPPs can be obtained in one-pot based on method (ii).