The preceding ten years have witnessed the RIV molecular propositions evolve from AIEgens, extraction directly from natural products emerges as a facile and cost-efficient alternative. In addition, due to the extracted materials' biocompatibility, these molecules could significantly contribute to photothermal antimicrobial applications, biomedical materials, medical photosensitizers, and polysensory probes . The development of new RIV-type AIE materials based on natural products can greatly improve the variety and quantity of such materials and expand their applications in life sciences .