Data Analysis: Data were analyzed using Spectronaut v18.4 (Biognosys) using BGS factory settings. A spectral library was created from fractionated peptide DDA using Pulsar, generated from an in-silico library based on mammalian protein sequences from Uniprot. DIA data were searched using the spectral library and the mammalian sequences. Uniprot accessions were mapped to gene names using the Uniprot ID mapper tool (). Missing gene names not assigned by the tool were mapped manually. Statistically-enriched pathways were identified using Reactome.