Numerous strategies for the peripheral editing of pyridines have been developed but, due to their inherent reactivity functionalizations at the C2 and C4 positions of the heterocycle prevail, with chemical modification at the C3 position still presenting a significant challenge. Classical C3-halogenation or C3-nitration via electrophilic aromatic substitutions suffer from harsh reaction conditions, excessive use of the desired pyridine, and low regioselectivity (Scheme 1B). Over the last decades, peripheral editing methodologies have emerged as a powerful tool for the introduction of substituents at the C3 position, primarily employing non-directed transition-metal catalysis , directing groups, and most recently a dearomatization-aromatization strategy (Scheme 1B). In this approach, electrondeficient azines are transformed into electron-rich intermediates (enamine, dienamine) that react with electrophilic reagents. Subsequent rearomatization leads to C3-substituted pyridine derivatives. Along this line, Wang and co-workers reported an one-pot borane-catalysed pyridine hydroboration tandem reactions. Herein, the nucleophilic 1,4-dihydropyridine (1,4-DHP) formed reacts with electrophiles (imines, enol esters, SCF3-, SCF2H-, -CN reagents) and undergoes subsequent oxidation to afford C3-functionalized pyridines. In 2022, Studer and coworkers developed an efficient C3 functionalizations of pyridines involving a bench-stable electron-rich oxazinopyridine generated from dimethyl acetylenedicarboxylate, methyl pyruvate and a pyridine. This intermediate, as dienamine, reacts with electrophilic reagents or radials leading to, after rearomatization, C-3 functionalized pyridines. By switching from an oxazino intermediate to a pyridinium salt, direct selective peripheral editing of pyridines at C4 was achieved. The McNally group proposed another strategy for C3-halogenation of pyridines that proceeds via ring opening, halogenation, and ring-closure for which they modified the classic Zincke reaction. Furthermore, they expanded their methodology to synthesize N-(heteroaryl)pyridinium salts, and to incorporate stable radioisotope N atom into the pyridine ring. In recent years, significant advances have been made in photoredox catalysis and have expanded the toolbox of radical transformations available to synthetic chemist. Recently, we and others have developed photochemical methods for the siteselective amidation of electron-rich double bonds using electrophilic N-centered radicals. 37 , 38 , 39 , 40 Based on reports concerning the functionalization of Zincke imines, and our studies on photochemical amination of dienol ethers, we hypothesized that selective C3-amination of pyridines could be achieved in a photocatalytic manner. Indeed, we demonstrate that N-centered radicals, generated from N-amino-pyridinum salts in a photochemical manner, react with Zincke imine to regioselectively produce, after rearomatization, C3-amino pyridines.