In this study, a new series of entirely bio-based copolymers containing poly(alkyl furanoate) as a hard segment and poly(dilinoleic furanoate) (DLF) as a soft segment with a 70-30 wt% ratio, respectively, were synthesized via an enzymatic process in diphenyl ether. The use of an immobilized form of enzyme allowed to perform the synthesis at a relatively high temperature (140 °C) enforced by the high melting temperatures of the furan-based copolyesters and poor solubility of the final products. The synthesis resulted in four different furan-based copolymers with high reaction yields (> 89 %).