The prospects for this work and the potential additions to it are very broad. There are over 150 different chemical structures of PHAs, depending on the carbon substrate used and the biosynthesis conditions. It would therefore be possible to develop a very wide range of sustainable plasticizers, using a "chem-biotech" approach. This study needs to be extended in a number of ways, in particular to assess the mechanical properties and rheological behavior of the systems developed. It is crucial to consider plasticizer migration studies as an obvious perspective to this first conceptual approach for the valorization of PHO-based plasticizers. Moreover, the hexyl isocyanate used to add alkyl chain ends is highly toxic, thus another synthesis route could be developed to reduce its toxicity. In this frame, it would also be necessary to establish toxicity tests for the systems developed for a plausible approach to replacing phthalates for a future that is more respectful of the environment and health.