This study used the MEME domain search bioinformatics tool to investigate the biological functions of the P protein of the EEEV virus. The study found that the EEEV virus's P protein has low-density lipoprotein binding domains, such as SRCR, as well as domains like Ephrin RBD, Granulins, and Sema, which can stop synaptic growth and remodeling. Other domains include potassium channel-like domains and guidance domains. This finding contributes to our newly acquired comprehension of the pathogenic mechanism of this neurological virus.