Although our tested datasets do not include very large molecules, explaining larger molecules is also possible. We calculated the Myerson values for MW prediction on the largest single DrugBank molecule (Semaglutide, 291 heavy atoms) which took 5:35 min on our machine for 1000 sampling steps, using the GPU (RTX 3090), a single CPU core (Ryzen 5975WX) and 5.75 GiB of memory. The prediction had an absolute error of 5.73 g/mol and a relative error of 0.14%, clearly illustrating that even large graphs can be explained on feasible timescales. However, one has to keep in mind that the accuracy of the sampled explanations decreases when the molecule size increases (Figure ) and that the calculation time is highly dependent on the model size and the used hardware.