There were several methods and approaches that were used to propose potentially synergistic drug combinations. As part of the DREAM challenge , the coordinators provided information about which drugs were used on 85 different cell lines and the targets of these drugs. It was the drug target list that was used for the potential combinations in the different approaches. The list of potential targets is found in the "targetlist.csv" file at . Table shows AKT 1 concentrations (µm) identified in the first column. ADAM17 (µm) is identified in the first row. The numbers in the second row and column are cell survival rates at the corresponding concentrations. The targets used were the Agent1 and Agent2 values from these tables.