This work shows that a bipolar membrane can be used jointly with a glycerol electrooxidation half-reaction to significantly reduce the overall cell potential for cathodic fuel-forming reactions under conditions independent of the GEOR half-cell. The BPM enables the pairing of an independently optimized cathode (or photocathode) for the reaction of interest while benefiting from the sustained voltage savings resulting from using the GEOR anode described here. Given the relatively low current densities, these results will be most beneficial in the context of PECintegrated systems rather than high current density electrolysis. For example, sustained -10.0 mA cm -2 for HER is a practical goal for a PEC system. Glycerol-assisted HER is possible at less than 0.7 V overall cell potential at that current density for extended periods. This is readily achievable with many single-junction light absorbers, including CdTe or perovskite-based PV. Additionally, > 20 h of electrolysis stability suggests that the electrocatalyst layers can be used over the course of a day and then regenerated overnight by electrochemical methods. Reducing the overall cell potential required to generate hydrogen simplifies the design of a PEC system and can leave a portion of the visible solar spectrum unabsorbed for other uses. If a semitransparent methylammonium lead iodide perovskite solar cell (band gap ≈ 1.7-1.8 eV) is used to drive glycerol-assisted solar-to-H2, the transmitted solar illumination could be collected in a Si bottom cell to generate electricity and enhance the efficiency of the process. The efficiency gains of the electrochemical/electrical processes rely on the constant consumption of glycerol as a fuel. This is not practical in general. However, coordinating PEC-based photoelectrolysis with biodiesel production could be practical and may improve the economic prospects of both technologies.