Before proceeding the next section on large molecules and ∆-Machine Learning, we make some brief remarks about datasets. This is a critical component of machine learned potentials, and a major discussion of it is beyond the scope of this Perspective. However, in a recent Perspective on the topic, we pointed out that our PIP PESs are built on datasets covering an extensive range of energies . This contrasts to popular datasets such as MD17 which are built from classical MD simulations at 300-500K and using DFT energies and forces. This data set was mainly created and used for testing many methods for MLPs.