This comprises 100 fragment-like molecules for which Pfizer's QM calculations of torsional profiles computed with HF/minix 75 followed by B3LYP/6-31G*//B3LYP/6-31G** differed substantially from those generated with the OPLS3e force field. Pfizer code for relevant related work is public on GitHub. Enumeration of conformers, but not of protonation states, led to 352 conformers.