The DS --C 12 E 6 potential energy decomposition for DS -binding to the ACWI (Fig. ) should be compared with the decomposition of the DS --water interactions for the same system (Fig. ). It is important to note that while the interfacial DS --C 12 E 6 electrostatics is far smaller in magnitude than the interfacial DS --C 12 E 6 LJ, the interfacial DS --water electrostatics and LJ contributions are relatively similar in magnitude. Therefore compared to water, the C 12 E 6 monolayer can be seen as a predominantly nonpolar medium.