Among the deadliest and most challenging to treat cancers are malignant primary brain tumors, encompassing different tumor types depending on the cellular origin . They are known to grow aggressively, infiltrating the surrounding healthy brain tissue in the process . Many of the emerging primary brain tumors are astrocytomas, of which glioblastoma is the most common representative . The World Health Organization (WHO) classifies glioblastoma as a WHO grade IV astrocytoma due to its aggressive and fast growth and the high degree of tissue infiltration . To this day, there is no cure and treatment is limited to improving the patients' quality of life until their inevitable death .