The work presented here has been carried out on an automated workstation manufactured by Chemspeed Technologies AG (See Supplementary Materials). Our investigation began by exploring the handling of reactive organolithium species on the automated workstation. An automated washing and drying of the reaction vessels, followed by purging of the sealed workstation with nitrogen gas for 90 minutes, enabled the generation of a moisture-and oxygen-free system. An automated titration of n-BuLi on the platform was conducted by dispensing increasing volumes of the organolithium into N-benzylbenzamide solutions at -40 °C and observing the color change at the equivalence point (Fig. ). Notably, no erosion of n-BuLi molarity was observed from the manual laboratory titer.