A previous paper outlined the concept of parameter-type based force fields using the SMIRNOFF format. In Parsley 1.0.0, most of the initial set of nonbonded parameters was ported from parm@Frosst into what we called SMIRNOFF99Frosst, an informal AMBER family small molecule force field. SMIRNOFF99Frosst was used as a starting point for Parsley with significant optimization of the valence parameters through fits with an extensive set of QM calculations. Since both GAFF and Parsley share roots in the AMBER family of force fields, this meant that their nonbonded parameters were virtually identical. Since the release of Parsley, we have made several updates to our force field, consisting of improved valence parameters as well as bug fixes. Parsley 1.1.0 included the addition of new nitrogen-centered improper torsion terms to better describe the planar and pyramidal structures that are often difficult to differentiate. This was followed by Parsley 1.2.0 which included a major re-design of the quantum chemical training datasets and a full valence parameter refit to this new dataset. This training data curation resulted in significant improvement in relative conformer energies, optimized geometries, and torsional profiles with respect to accurate high-level ab initio data when compared to Parsley 1.0.0. Revisions after Parsley 1.2.0 include new torsion parameters for dialkyl amides in Parsley 1.3.0 to improve amide torsional energy profiles; in Parsley 1.3.1, a minor regression in the accuracy of the description of sulfonamides was corrected. Building on the foundation of Open Force Field Parsley generation of force fields, we now introduce the OpenFF Sage 2.0.0 small molecule force field which extends our previous work by continued refining of valence terms and, for the first time, refitting the LJ parameters. Like Parsley, Sage is applicable to druglike molecules covering the chemical space C, H, O, N, P, S, F, Cl, Br, and I, and the monoatomic ions Li + , Na + , K + , Rb + , F -, Cl -, Br -, and I -. Sage again included substantial work retraining the valence parameters used in Parsley, but the most significant update to Sage is the re-training of select Lennard-Jones (LJ) parameters to physical properties. LJ parameters in previous generation Open Force Fields were taken from AMBER parm99 and parm@Frosst 7 force fields. The LJ parameters in Sage 2.0.0 were optimized against condensed phase physical properties, including enthalpy of mixing and densities measured for both pure and binary mixtures. The inclusion of such properties measured for mixtures has been shown to be critical to accurately capture interactions of unlike chemistries. Physical properties of aqueous systems using TIP3P water were directly included in the training set ensuring maximal self-consistency between the small molecule and water interactions. TIP3P was chosen as this water model, as it has typically been considered the default for AMBER-style force fields. Sage is most similar (though not equivalent to) an AMBER force field because of its roots in the AMBER-variant Parm@Frosst, and AMBER forcefields for proteins and nucleic acids are tested and recommended with OpenFF small molecule force fields. Thus it seemed necessary to use TIP3P at least until we are able to refit a fully consistent biopolymer and small molecule force field for compatibility with an alternate optimized water model.