First, we fine-tuned GB-FFs models on the SPICE and DES370K databases, which explore a wide range of the chemical space. The resulting Root Mean Square Error (RMSE) of the model for SPICE energies is 3.06 Kcal/mol, improving that of the original GAFF, which exhibits a 6.03 Kcal/mol error. The GB-FFs model also improves the GAFF performance on the DES370K database.