To achieve the control over the interface polymorphism in an experiment, having multiple, independent handles is desirable. Therefore, we investigate how the commonly used handles deposition temperature, deposition pressure, and electric field interact and influence the interface polymorphism. We do this using ab-initio thermodynamics, which has been applied to many different interface systems to analyze the temperature and pressure dependencies. Because most studies are done without electric fields present, the fielddependent terms, to the best of our knowledge, cannot be found in literature. Because it is a priori unclear how large they are, it is necessary to briefly revisit the ab-initio thermodynamics treatment and the commonly made approximations. In the following, we show that for TCNE/Cu(111), the field-dependent terms are generally small, but highlight that this is not necessarily always the case.