Reactions were carried out under inert atmosphere (N2) using flame-dried glassware and anhydrous solvents, if not indicated otherwise. Reactions of Fdx with thiol nucleophiles were performed without any precautions to avoid air or moisture and solvents used were not anhydrous. Detailed information on the reaction conditions, experimental procedures, instruments used, and the characterization of all newly synthesized compounds including 1and 2-D NMR spectral data can be found in the Supplementary information.