In addition to accurate ab initio DFT-D4 energy orders and strain energies of conformations, this database provides extra quantum mechanical information. I performed statistical thermodynamic calculations using the GFN-XTB and PM6-D3H4X quantum mechanical semi-empirical methods for all conformations of all drug molecules with our qfLowerLevel.x application. With all necessary thermochemistry quantities for all conformations, I also calculated the Gibbs free energies for the conformational ensemble of all drug molecules using our qfensamble.x program. The Gibbs free energies for the conformational ensembles are written to individual log files for each SDF file by adding a simple .log extension, as this value pertains to the entire conformational ensemble of the given drug molecules. As a result, the number of files is doubled in all directories of thermochemistry calculations.