For DS -binding to the ACWI, the panels a and b of Fig. shows the decomposition of E U,V into DS --C 12 E 6 (a) and DS --water (b) interactions, with each plot further decomposing each interaction into the electrostatic and LJ contributions. Considering energies relative to bulk-DS -(see Sec. II C), a clear picture emerges from the sign of each term in the interfacial region, namely that repulsive (less attractive) DS --water interactions due to surface adsorption indicate a (partial) water-desolvation of DS -from the bulk water solution, and similarly, the attractive DS --C 12 E 6 interactions as a result of surface adsorption indicate a "resolvation" of DS -into the C 12 E 6 monolayer.