where [𝑀 ! ] and [𝑀 " ] are the solution concentrations of each monomer type. Equation 1, frequently referred to as the Mayo-Lewis equation, is oftentimes expressed in terms of mole fraction of each monomer in the feed solution and in the polymer. At the time of its derivation, the differential nature of the Mayo-Lewis equation prompted the development of simple, linearized methods to extract reactivity ratios from copolymerization data generated from multiple reactions run to low conversion with different comonomer feed ratios. Due to the difficulty in evaluating differential equations without modern computational tools, these methods have been widespread