A key tool for resolving structures of a molecules such as AMPs . Its advantage relies on a strong chemical and structural characterization of molecular structures, yet it requires large instrumentation with isolated and well prepared molecular samples and intense data interpretation. Enzyme-linked Immunosorbent Assay (ELISA), quartz crystal microbalance with dissipation monitoring (QCM-D) and related techniques: These techniques allow to explore binding affinities between molecules such as AMPs on surfaces or membranes with greatest details .