Introduction. Heterocycles are prevalent in bioactive molecules and ubiquitous in modern synthetic chemistry. As such, developing methods for the selective functionalization or modification of heterocycles remains a pressing aim for pharmaceutical and agrochemical discovery campaigns. Transformations that achieve single core-atom changes to heterocyclic structural motifs at a late stage -often termed "skeletal edits" -have emerged at an increasing pace in recent years. These transformations complement more established peripheral diversification methods and enable efficient access to less explored regions of chemical space without requiring de novo synthesis.