The presented simulation results imply that the feed-related gradients found for example in large-scale bioprocesses could be diminished considerably by dividing the feed into multiple symmetrically positioned points. Similar benefits could also be anticipated in other contexts. An order-of-magnitude reduction in the macromixing time-scale could make large-scale equipment behaviour resemble laboratory-scale performance, which in turn should alleviate mixing-associated problems encountered in the scale-up. However, in a bioprocessing context the prevention of contamination would also need to be accounted for upon implementation.