Besides the higher activity of both the homogeneous and heterogeneous systems compared to their Co-porphyrin counterparts, ZrCo-MOF exhibits greater stability under the reaction conditions than Co-PCN-222, most likely due to the elimination of triethanolamine as sacrificial donor. A further improvement to the system described here would be the elimination of organic solvent: while we demonstrate here that the [Co(dmgH)2pyCl]-based system can use water as the source of protons, ZrCo-MOF lacks the requisite stability in water to make such a heterogeneous system feasible. Alternative MOF-based systems based on water-stable MOFs should be investigated. While cobaloximes are cheaper and easier to prepare than porphyrins, the preparation of [Co(dcpgH)(dcpgH2)Cl2] linker is a multi-step synthesis and therefore simpler cobaltcontaining MOFs, such as MOFs that utilize Co as the node or incorporation of catalysts through post-synthetic incorporation, is an intriguing direction with more potential for industrial scale up. In the future, the use sacrificial donors could be avoided by coupling the oxidative reaction to produce value-added products. Another improvement to our system would be to exploit this catalytic cycle in electrochemical thin films or a photoelectrochemical cell, thus avoiding altogether the use of the sacrificial electron donor. Another exciting possibility is to combine the adsorption capacity for acetylene of previously reported porous materials with the (photo)catalytic properties reported here.