The main results showed that: the variation of the percentages of the dry mass to fresh mass of Centella asiatica is not significantly different between the VIETGAP and ORGANIC samples (Fig. ). The yields of the extracts from the dry mass materials for VIETGAP sample reached the maximum values in February and April 2021 with 36.74% and 32.86%, respectively. In the year 2022 the yields were a little lower, maybe due to the age of the herb, which was planted in October 2020, or because of the differences in the climate conditions between 2021 and 2022. for both VIETGAP and ORGANIC samples (Fig. ), when the air temperatures were high. All three triterpenoids madecassic, asiatic and terminolic acid accumulated predominantly in the glycoside form in January, September and October 2022 for both VIETGAP and ORGANIC samples. These results are significant and will be interesting for the planning of the harvest times of Centella asiatica in regard to its utilization in the preparation of the pharmaceutical products, of the cosmetic or for the study on the chemical transformations (derivatization) of the triterpenoids. Most importantly, our results show that there is no drawback to using the ORGANIC production method compared to the VIETGAP method. This means that negative environmental and health impacts of cultivation of the herb can be reduced without any compromise in yield of valuable bioactive compounds which could form the basis of future medicines.