Interaction energies presented in this work are all counterpoise-corrected and in this section we examine the effect of the DLPNO approximation on that correction. Figure compares DLPNO errors for the L7 + bbr data set, with or without counterpoise correction, evaluated at the RI-MP2/cc-pVXZ level with X = D or T. Errors are much smaller when ∆E is counterpoise-corrected, indicating significant cancellation. For the counterpoisecorrected results, both basis sets behave similarly and the mean DLPNO error is about 2 kcal/mol for loose-CCSD(T) thresholds, although individual errors range up to 8.4 kcal/mol. DLPNO errors are much larger for uncorrected interaction energies, however. This behavior has no precedent in smaller complexes such as the S66 dimers, where counterpoise correction modifies the error statistics by 0.2 kcal/mol, even in double-ζ basis sets. For L7 + bbr, the DLPNO errors range up to 20 kcal/mol for cc-pVDZ and up to 16 kcal/mol for cc-pVTZ, in the absence of counterpoise correction, suggesting that this correction should be considered mandatory for non-covalent interaction energies evaluated within the DLPNO approximation. Agreement between counterpoise-corrected and uncorrected values of ∆E has sometimes been used as a criterion to indicate convergence to the CBS limit, 60,100 but that is not a viable test for DLPNO calculations in large systems, due to sizable errors in the uncorrected results. The "half-counterpoise" procedure (averaging corrected and uncorrected values of ∆E) is similarly illadvised under these circumstances.