Given that our objective is to use molecular simulation as a screening method and our emphasis on the importance of running replicate simulations, we need to be able to execute a substantial number of simulations at a reasonable cost. As such we choose to explore the potential of relatively short time scale simulations to provide insight. While extensive and intricate simulations have the potential to enhance output precision, they typically entail a substantial per-simulation cost, impeding their economic and temporal viability. Simulations that are more expensive and take longer than experimental studies cannot in good faith be proposed as a viable screening option. Consequently, striking a balance between accuracy, speed and cost becomes imperative.