The diffraction experiment at 200 kV was performed using a ThermoFisher Tecnai G2 microscope with a LaB6 gun. The microscope was operated in spot size 9, keeping the exposure time 1 sec and beam diameter 2 µm constant. The beam current was measured using a screen readout calibrated using a Faraday cup. The dose rates of 1 e -Å -2 s -1 , used for the experiment, were calculated by dividing the beam current of 0.050 nA with an area of a beam with a radius of 1 µm. The sample screening was done in imaging mode at 11 kx magnification with an exposure time of 40 µsec. The beam was blanked as soon as the ZIF-8 particles were in the field of view, and the microscope was switched to diffraction mode. The exposure time and camera length were set to 1 sec and 200 mm, respectively. The series of ED patterns were recorded using a TVIPS Temcam-XF416 camera (4k x 4k px, pixel size: 15 µm) at a constant dose rate until all the Bragg planes disappeared. All the experiments were repeated three times for better statistics. The diffraction patterns were recorded from the camera's center region, which was 768 x 768 px and had a pixel size of 0.024 1/nm.