We can now reinterpret this quote in the context of the development of an integrated molecular discovery platform that we name a "matter computer". These computers process chemicals instead of information. Their "registers" consist of actual chemical, solvents, nanoparticles, etc. Their information processing subroutines are actual synthesis and characterization tools. The output of the computer is matter that can be readily analyzed and acted upon. They are the analogues of 3D printers but with molecular building blocks. All of these components should be connected to a central control system and database that can make artificial-intelligence-driven decisions about what do synthesize next. To understand the chemical space to be explored, these matter computers employ large computer-generated compound screening libraries or generative models based on their data. This loop requires the integration of several technologies that are currently emerging in an integrated platform .