Nuclear Magnetic Resonance (NMR) spectroscopy is a very powerful technique in studying the structure and dynamics at the atomic and molecular level of liquid or solid matter. Thus, NMR spectroscopy can potentially provide precious insights into the various transient species formed during the nucleation and crystallization processes. For example, the CLASSIC NMR approach exploits alternate acquisition of both liquid-state and solid-state NMR (ssNMR) spectra as a function of time to obtain complementary information on the time-evolution of both the solid phase and the solute species during a crystallization process. However, conventional NMR approaches often face limitations due to the poor intrinsic sensitivity of NMR spectroscopy, which implies long acquisition times that prevent the study of fast reaction processes. The use of hyperpolarization methods such as dynamic nuclear polarization (DNP) can be a partial solution to track transient solute species such as PNS. Indeed, dissolution DNP (dDNP) allows the acquisition of NMR spectra on a very short time scale (0.5 s -1 ) and has been successfully used to monitor the formation and the evolution of PNS for calcium phosphates and carbonates in fast mineralizing solutions. The rates of formation, aggregation and kinetic exchange with free ions involving PNS can be determined using this approach. However, limitations exist as dDNP equipment is rare, and 2D experiments cannot be recorded with dDNP (unless by combining with single-scan methodologies).