After membrane fusion, the nucleation of a nascent fusion pore (which in thermodynamic terms is the first step in the formation of a new configuration) can follow different possible paths: dilation (meta-stabilization), transient flickering (open-close repetitions) or kiss-and-run resealing (the metastable pore closes and bilayers evolve towards full recovery). Therefore, the complete free energy landscape along the different stages of the fusion pore becomes a desirable description to quantitatively determine the position of local minima that could restrain the fusion pore from evolving in either one of these paths.