The synergistic effect (and the solute-solvent energy and entropy components) for DS 0 adsorption shown in Fig. is qualitatively similar to the DS -synergistic effect indicating that the observed attractive DS -synergy is dominated by the van der Waals interactions with C 12 E 6 (see Sec. III E). This also agrees with the interpretation that the cavity effect dominates -T ∆ C S DS -,W ⊕C (z). The synergistic effect for SO 4 CH - 2 shown in Fig. remains mostly flat up to the GDI but becomes attractive at the ACWI free energy minimum showing that the C 12 E 6 monolayer has a net-stabilizing effect on the small ionic solute.