Notwithstanding, we can take a more glass-half full look at some recent developments that are both linked between themselves and have the potential to improve the situation. These are Open Science, Open Access (OA), FAIR (Findable, Accessible, Interoperable and Reusable) and WikiData. While there is certainly momentum behind the first two trends, the persistence of publisher paywalls still remains a serious obstacle (e.g. of the 62K papers curated by ChEMBL in EPMC only 8.5K are full-text and only 0.6K OA). Strong community momentum (including from publishers) is also building behind FAIR, which, in principle, should encompass accessibility to D,A,R,C and P (even if not their explicit connectivity).