The results for both models are shown in Table . Across the test set, the general model predicts a density error of ϵ ρtrue = 1.13 + 0.02%. While the error is low, it is larger than that of the DNA only model (ϵ ρtrue = 0.92%), reflecting the greater complexity of the solvated DNA system. Somewhat disappointingly, the distinct water model shows no improvement over the general model with an error of around ϵ ρtrue = 1.17 + 0.02%. But on a positive note, this implies that the general model sufficiently distinguishes the chemical environments for DNA and water without needing distinct element types for DNA and water atoms. Therefore, the general model was used to obtain the remainder of the results in the study. 1.13 ± 0.02 0.063 ± 0.037 distinct waters 1.17 ± 0.02 0.0019 ± 0.044 Density difference plots can be used to obtain a physically meaningful picture of the DNA-solvent interaction for a static configuration. The plots were constructed from the following steps: