To correct for the unspecificities caused by increased molecular weights and hydrophobicities , the Ligand Efficiency Lipophilic Prize (LELP) unique parameter was chosen among other alternatives . LELP was applied after converting the Kcal/mol of the ADV output values to Ki in nM by the formula 10 9 *(exp (Kcal/mol/0.592) ). LELP was then calculated from the nM values by DW chemical property options.