Commercial adenosine derivatives (ATP, ADP and AMP) complex well with the nh-PHIP catalyst, resulting in four well-defined hydride signal pairs around -21.5 ppm (HX) and -22.8 ppm (HA) (See Figure (A) for ATP and SI for full spectrums for all three compounds). Up to now they have not been detected in complex biofluid by any of the hyperpolarization methods.