Starting with the OpenFF 1.0.0 (Parsley) force field , we use this data to train 12 Lennard-Jones parameters ( and for 6 LJ types) against data for alcohols, esters, ethers, ketones, acids, and alkanes, with property measurements chosen from four training sets containing different combinations of physical properties. To test the performance of the refitted force fields, we benchmark the results of this optimization against a larger test set of physical property measurements for the same moieties, consisting of ( ), Δ ( ), , and Δ measurements.