In our investigation of the cluster binding free energies and hydrate distributions, we find that the organic acids PA, LA, ProA, and diol are not hydrated in the gas-phase. On the other hand, we find that the pyruvic-acid containing clusters and the pyruvate-containing clusters with ions present are significantly more thermodynamically stabilized in the gasphase with the Na + ion contributing the most to this stabilization. This suggests that for organic acids, to efficiently transition from the gas-phase to the particle-phase, some interfacial surface ions should possibly be present to facilitate the process.