 Closed-source, platform-specific software has caused lock-in effects, restricting users to specific tools and hindering innovation. Until recently, major instrument vendors lacked open-source, cross-platform libraries for data access, limiting data reuse and algorithm development . Thermo Fisher's RawFileReader library marks important progress in this respect, enabling tools like ThermoRawFileParser and PRIDE Archive USI . This idea has been recently extended for Bruker timsTOF data with the timsrust library (), which is open-source and already used by tools like the Sage search engine .