In most of the countries the distribution of the score is around the numbers one and two. The presence of at least one peak around the number one and two is especially noticeable in the case of Brazil, Costa Rica, El Salvador, Mexico, and Peru. A possible explanation for the peaks around the NP-likeness one and two is that a certain combination of NPs fragments is mainly present in LANaPDB. COCONUT and approved drugs calculated with three different algorithms: A) Natural product-likeness calculator B)