where n d,0 is the initial number of water molecules in the nanodroplet, and τ is the droplet disintegration lifetime. Herein, the conservation law implies that the rate of water transfer to the oil phase is given by, dn oil dt ∝ -dn d dt ∝ n d . Integrating, the number of water molecules in the oil phase evolves as, n oil (t) = n oil,0 +n d,0 1 -e -t/τ , where n oil,0 is the number of water in the oil phase at the initial time. Notably, for this calculation, dangling water molecules at the droplet interface are considered to have moved to the oil phase. This formulation points that as t → ∞, n d → 0 and n oil → n w , indicating the complete disintegration of the nanodroplet at infinite time. However, the state of complete nanodroplet disintegration is challenging to achieve though unconstrained allatom classical simulations. Therefore, we focused on fitting only the initial decay phase of water loss from the nanodroplet.