structural diversity of C, B, Ge centered spirocycles, it remains notoriously difficult to construct these chiral spirocyclic skeletons, particularly in a unified strategy or in an enantioselective manner. Methods to construct carbon-centered chiral spirocycles typically involve direct bond formations at the spirocenter. An enantioselective construction is achieved by differentiating functional groups near the spiro carbon atom via proximal stereocontrol (Fig. ). The performance of the chiral catalysts is generally restricted to specific quaternary chiral spiro centers, often resulting in limited scope and reduced applicability. There are additional drawbacks in the construction of scaffolds featuring multiple functionalities where stereochemical information extends far from the spirocenter. Accessing such elaborate chiral spirocyclic skeletons usually require lengthy routes such as modifying synthesized prochiral spirocycles, or racemate resolution via chiral high-performance liquid chromatography (HPLC). ( ) Moreover, established strategies cannot simply be extended to access chiral spirocycles with different central hetero atoms such as boron and germanium due to their unique and different reactivities (Fig. &). Obtaining these enantioenriched products rely on nucleophilic substitutions and racemate resolution via chiral HPLC. Therefore, the enantioselective construction of boron and germanium-centered chiral spiro skeletons remains a formidable challenge.