Our workflow allows us to generate microactuators in a simple 3D-prin�ng setup that does not require any addi�onal instrumental or manufacturing modifica�on. By combining alignment paterns with specific geometries, one obtains a very large and complex design space. Because both alignment and the effect of actua�on can be described by appropriate theories, the door is now open for ra�onal design of 4D-prin�ng solu�ons, including the possibility to use machine learning approaches to achieve desired design features, in analogy to similar developments in the field of nanophotonics . minutes each and then treated with a plasma cleaner (Harrick Plasma). To achieve a 90° anchoring of the LC director to the substrate, a 100 µL of polyimide (Nissan SUNEVER® SE-5661) was spin-coated onto the glass surfaces at a spinning speed of 300 rpm for 5 seconds, followed by an accelera�on to 4000 rpm for 20 seconds. The coated substrates were pre-baked at 80°C for 2 minutes and then postbaked at 220°C for 30 minutes to complete the polymeriza�on.