As concerning their potential use for therapeutic purposes, it is important to underline that we have previously shown that both the natural and biomimetic chromophore should present nonnegligible cross-section for two photon absorption, hence allowing to displace the absorption to the red or near infrared portion of the spectrum. However, the perturbation of the membrane, while unambiguously determined are still modest, thus a molecular design leading to the inclusion of bulkier substituents should be considered as a suitable strategy to increase the LAT potential.