In generating eLCB acquisitions for more than one target, our results further highlight the importance of choosing targets with dissimilar landscapes to guide the data collection. In the case of lignin yield and β-O-4 content, we see that their respective eLCB acquisitions are complementary since high target values are attained for high and low P f , respectively (Fig. ). In contrast, similar landscapes would lead to similar suggestions for new experiments and, consequently, slower model convergence.