To demonstrate a proof-of-concept of a fully closed loop of automated experiment planning and execution, we designed a multi-objective campaign for the synthesis of Bis[(N-carbazole)styryl]biphenyl (BSBCz) derivatives based on previous work. The campaign goals are to simultaneously maximize the experimental gain cross section and the simulated lasing gain factor (produced via DFT simulations), involving BO-based experiment planning, automated synthesis, purification and functional characterization, as well as simultaneous computational simulation via the AiiDA module.