Comparable crystals could be obtained by solvothermal synthesis in fused-quartz vials and by solvent diffusion (i.e. layering) of ligand and cadmium acetate solutions in quartz tubes at room temperature. The solvothermal growth was carried out in DMF at 105 o C for 24 hours. We also layered two DMF solutions, one of ligand and one of cadmium acetate, with a solvent layer in between (DMF with CH3OH in some cases) in which crystals grew. These crystals were analyzed after 24 hours. Optical microscopy, scanning electron microscopy (SEM), and X-ray microtomography (microCT) revealed the formation of the dissymmetric, chiral, trapezohedral crystals (Fig. ). Ideal trapezohedra are staggered, achiral, bipyramids with 622 symmetry. Our enantiomorphs featured an apparent rotation or twist of the top pyramid with respect to the bottom (Fig. , S1, S2, for example). The off-set angle of 5.9 o (± 0.2) has a clockwise or counterclockwise sense forming right (R) or left (L) arrangement of the principal facets. The size and shape uniformity of the crystals is high with typical dimensions of about 100 µm (L) ´ 60 µm (w). The handedness of 4600 crystals from five batches were established Pasteur like -by optical microscopy (49.4% R, 50.6% L; Table ). The ensemble is essentially racemic. The growth of the crystals was monitored in situ by optical microscopy, at room temperature for more than 11 hours (Fig. ). The apparent bipyramidal offset that defines the morphological dissymmetry was observable after 1 hour when the crystals were still about one-fourth as long as their final size. According to symmetry rules, the faces {hkl} of enantiomorphous dihexagonal bipyramids must have h ≠ k.