Different post-polymerization concepts like modification of polymeric active esters, anhydride, isocyanates, oxazolones, epoxides, Michael-type addition reactions, modification by thiol exchange, etc., have been reported for functionalization of polymers . PPM used for bioconjugation, in particular, should offer high efficacy under mild conditions. In the last two decades, click-chemistries have had a major impact in the field of bioconjugation .