We initially took inspiration from previously established techniques known to create fragmentation products such as Desorption Atmospheric Pressure Chemical Ionisation (DAPCI). DAPCI utilises toluene or methanol vapours in nitrogen flowing across a DC corona discharge to both desorb and fragment trace analytes -we aimed to minimise desorption while maintaining the radical-induced fragmentation, maintaining analytes insitu. This was achieved through construction of an in-house Direct Current-Argon Plasma (DC-AP) discharge source consisting of a 5kV HVDC power supply attached to a 1 MΩ resistor and a brass t-piece containing a corona needle within an isolating plastic sheath, and gas tubing (Figure ).