Mass spectrometry analysis of these cells show clear ability of SCREEN to distinguish cells that were treated by drugs cocktail, and this separation is due to changes in the proteome where proteins most probably are responsible for cell activation of death pathways. Cells that were treated by doxorubicin solo treatment are still remain resistant to that type of treatment. This exemplifies a clear advantage of this type of analysis over bulk measurements, where we see single cell reaction to drugs cocktail treatment for leukemia doxorubicin resistant cells.