This entails simultaneously depositing a single one-dimensional bias for each torsion in the molecule, thus promoting exploration of the rotation of that torsion. . The cost of this approach scales linearly with dimensionality (shown in Figure ), as one additional monodimensional grid is needed for each additional torsion considered. The cost savings of this approach come with a trade-off; conventional metadynamics promotes the exploration of the entire conformational phase space and guarantees that previously visited configurations will be penalized accordingly.