Like VOR, BEX being a third generation retinoid is also an anticancer agent used for the treatment of cutaneous T-cell lymphoma . According to Ra calculation, the compatibility should be in the order pBuOzi > pPentOx > pPrOzi > pBuOx (Figure ). In contrast, experiment showed that pBuOx based triblock showed the highest solubilizing capacity for BEX (≈ 1.1 g/L at 4 g/L BEX feed) (LC ≈ 10 wt.% and LE ≈ 55%) (Figure ). The aqueous solubility of BEX was found to be 0.004 g/L (Table ). In all other triblock copolymers, solubility of BEX fell below 0.5 g/L. No clear trend between the four individual polymers was observed in formulation experiments when compared to compatibility estimation.