Chemical Similarity Enrichment Analysis (ChemRICH) for patRoon suspect screening, Table patRoon non-target screening, and Table for MS-DIAL. .1 for detailed information about Level 1-3 compounds, and Table .2 for the Level 5 compounds. Overall, the overlap between the different suspect lists was low (Figure ) confirming the need for the complementary suspect screening approaches applied here. While most of the unique features were found in the largest lists (TOP1, HMDB-CSF), the highest confidence features (Level 1) were exclusively found in HMDB-CSF (metabolites previously identified in CSF) and SC20