The code number IPR006600 represents an HTH CenpB-type DNA binding domain. The CENPB-type HTH domain is a helix-turn-helix (HTH) domain that binds DNA and is found in transposases and eukaryotic centromere proteins. There are two DNA-binding HTH domains in CENP-B's N-terminus that bind to the primary grooves of adjacent DNA. A psq-type HTH domain, that is C-terminal to a CENPB-type HTH domain, forms the N-terminus of CENP-B. These two HTH domains specifically bind the CENP-B box, present in the alpha satellite DNA of human centromeres, when they combine. Mammalian centromere protein B (CENP-B) is a protein that is specifically binds DNA to the CENP-B box and is associated with centromeres. It contains CENPB-type HTH domains. The transposable elements Tigger and Mammalian Pogo are present.