In order to investigate to what extent the extracted reaction templates are generally applicable and to what extent they are specific, we inferred partial ITS graphs from a subset of the USPTO_50K dataset. The 50,012 reactions were categorized into ten distinct classes by Schneider et al. To allow for a direct comparison with machine learning approaches, we followed the suggestion of Coley et al. and divided dataset into 8:1:1 and used 80% of the data to extract the reaction templates. Since there is currently no learning involved in the rule extraction, the validation and test sets are equivalent, and we use both to test SynTemp.