We introduced the kinetic selectivity achievable in nanoporous crystals for the first time into the domain of chemical sensors. Based on a novel temperature-perturbation method, VOC diffusivity values could be measured in a fixed atmosphere, and a single kinetic selectivity sensor could differentiate and quantify these analytes at ppm concentrations, even in mixtures containing high water vapor concentrations, outperforming a state-of-the-art electronic nose. 20 Harnessing the structural diversity of MOFs in kinetic selectivity sensors will enable the development of highly adaptable sensor arrays, opening the door to a wide range of VOC measurement applications that have previously been limited by the lack of selective sensors.