Molecular dynamics simulations allow us to assess trends in the thermal interface conductance that can be difficult to explore experimentally due to limits in measurement sensitivity and particle monodispersity. We simulated four nanoscale-gold surfaces with different curvature under two wetting conditions (moderate vs poor), and subjected each gold structure to various heating intensities to account for the effects of temperature increases during plasmonic heating. Altering the gold wettability allowed us to account for how differences in the gold-water interaction potential could affect the heat transfer, while also approximating the effects of coating the gold surface with ligands of different hydrophilicity. First, we confirmed that our results for the interface thermal conductance fall within the range of values reported from experiments. By comparing our results along with those from experiments to the critical value of the interface thermal conductance, we confirmed that the thermal interface conductance is an important element of AuNP heat dissipation, particularly, for small AuNPs (≤ 10 nm in diameter). Next, we analyzed the heat flux dependence and curvature dependence of the interface thermal conductance at the two wetting conditions. Our analysis indicates that the thermal interface conductance increases with curvature under both wetting conditions, but it increases non-linearly with heat flux only under moderate wetting of the gold surface. We found that the curvature dependence of the interface conductance coincided with a curvature dependent increase in water adsorption at the gold surfaces, consistent with trends observed previously for a simpler model of solid nanospheres immersed in monoatomic fluid. We also observed a temperature dependent shift in the water vibrational density of states that improved the VDOS overlap with that of gold. This improved vibrational overlap may account for temperature dependent changes in the interface thermal conductance under the moderate wetting condition. This work advances our understanding of how temperature and curvature affect the thermal conductance across nanoscale gold-water interfaces.