From Eq. 6, there is a point in which ϕU T = E a such that the relative change is zero, shown in Figure by the yellow area. As states become further from the crossover point in yellow, the absolute value increases. Interestingly, the intermediate value regions near the sign crossover, orange/red and green/light blue, widen at larger total energies. This is most evident by the dispersion of the largest positive values, in white coloring, that fades away at higher total energies (low activation barrier). Hence, while the general trends of Eq. 6 show that putting more total energy into the system will make mechanochemistry preferable, there is a diminishing return on investment. However, under conditions such as strong shocks, there is enough strain energy added that the total change in kinetic rate can easily reach a 50% increase in HE materials. Generally, the absolute values of this plot can be shifted by changing ϕ (different deformations). Figure shows trends in the same relative change in the kinetic rate value as Figure , but for changes is ∆U with different total energies (different colored lines), at a constant activation barrier of 32.0 kcal/mol. For low total energies, where the value of the relative change is negative, increasing the strain energy leads to a significant change in 1 k ∂k ∂△U . From Eq. 6, when normalized by k , an increase in the amount of ∆U only changes the coefficient term of Eq. 6 via 1 T 2 , in which the total energy constraint (cost function) lowers temperature with increasing strain energy. When ϕU T > E a and the sign of the relative change flips, there is considerably less change in the response with increasing ∆U . This is due to, at a much higher total energy, the relative change in the 1 T 2 term being much smaller. However, it should be noted, the total change in the kinetic rate for some ∆U is the integral under the curve, not the value of the curve itself. Hence, where mechanochemistry is more efficient, U T > 3200K in this case, adding more strain energy would still lead to a significant increase in reaction rates under total energy conditions, but the inverse effect at lower total energies (U T < 2000K) is a significantly more costly change.