A practical perspective to the continued improvement of CADD and AI, besides the methodological challenges and their application in drug discovery projects, is the convenience of formal training and education at the undergraduate and graduate level. Several practitioners learn and practice CADD "on the fly" as the research needs emerge. Formal training at early ages would prepare better researchers and practitioners of CADD, AI and it will be advantageous for the continued improvement of communication between multidisciplinary research teams so that experts in CADD can communicate more effectively with medicinal chemists and other drug discovery team members.