2,3-Dichloro HECP was reported in synthesis of thiazacridine derivatives as anticancer agents against breast and hematopoietic neoplastic cells , whereas 2,4-dichloro HECP was in synthesis of some new dihydropyrimidine derivatives by cyclization of polarized unsaturated systems . Synthesis of multifunctional polymer containing Ni-Pd NPs via thiol-ene reaction for one-pot cascade reactions mentioned 2,6-dichloro HECP . 3,4dichloro HECP was reported in a highly efficient protocol for the regio-and stereo-selective synthesis of spiro pyrrolidine and pyrrolizidine derivatives by multicomponent reaction .