The glucose sensing strip equipped with the O2-scavenger was tested both in the amperometric and in the coulometric mode under various temperatures (Figure ). For the same glucose concentrations (12 mM), the amperometric mode delivers a standard deviation of 19.6 % on average while the coulometric mode has an average standard deviation of 7.5 % in the temperature range from 5 to 45 °C (Table ). The amperometric operation has a fast response time, but is more dependent of external parameters such as temperature which influence the enzyme activity or mass transport and thus lead to fluctuation in the current reading. In contrast, the electrical charge extracted in the coulometric mode is highly reproducible, regardless of the external temperature.