The experimental workflow for the calibration of the FTIR was automatically executed and a standard addition approach was used. First, 6 different levels of ester, amine, TBD and solvent were generated and directly analyzed by FTIR, without passing through the reactor (Figure ). The product standard addition was performed by allowing a certain reaction composition to pass through the reactor and dosing 6 different concentrations of product to the outcoming reaction mixture of the reactor (Figure ). The assignment of the concentration values with the standard addition is outlined in detail in the supporting information.