For the GPCR case a slight increase in performance occurs when assay description embeddings are used as additional input descriptor (R 2 of 0.71). This effect is consistent across both the random split and the more challenging scaffold split. Moreover, for GPCRs the RMSE and Kendall's Tau correlation coefficient exhibit a consistent improvement when using the embeddings. However, no significant improvement occurs upon adding the assay embeddings to the SLC and tyrosine kinase models.