reported the ATRP of a monosubstituted acrylamide containing the amino acid moiety N-acryloyll-alanine (AAla) in the presence of two independent initiators at room temperature: sodium 4-(bromomethyl)benzoate (SBB) and 2-hydroxyethyl-2′-methyl-2′-bromopropionate (HMB). However, the technology must be further refined before it can replace conventional manufacturing methods. But their extensive use to design advanced materials for the above-mentioned applications is limited. This can be explained in terms of the following reasons: Easy, quick, reproducible tailoring of stimuli-responsive polymer networks based on polymers is still in its infancy. Reports on the zinc catalyst-mediated RDRP are quite rare. Among these is the ATRP of methyl methacrylate and styrene at 80 o C mediated by zinc oxide nanowires. Furthermore, RAFT of N,N-dimethylacrylamide, benzyl acrylate, benzyl methacrylate, and 2-hydroxypropyl methacrylamide in the presence of ZnTPP 23 at 25 o C was conducted on methacrylate, methyl methacrylate at 25 o C. Zinc (Zn) catalyst is one of the most recently developed RDRP catalyst However, the Zinc catalyst has not been explored as a catalyst for amino acid based RDRP. The Zinc catalyst has not been explored as a catalyst for amino acid based RDRP. To the best of my knowledge, there is no report Zn-mediated RDRP of AAla and It's Block copolymer. Herein, the research report, for the first time, zinc catalyst -mediated RDRP of monomer, leading to the synthesis of PAAla at ambient temperature and a well-defined pH-responsive amphiphilic diblock copolymer poly(L-alanine acrylamide)-block-poly( methylmethacrylate (PAAla-b-PMAA). Thus we believe that this block copolymer will be employed for encapsulation of toxic dye from the waste water.