The recent advances in polymer processing techniques enabled to achieve very complex product shapes and functionalities. One of the key features of advanced processing technologies, such as AM, is their ability to design and fabricate custom-made products . The AM (known also as three-dimensional printing, 3D printing), which aims to build 3D objects, very often complex in shape, by computer aided design (CAD), has gained great interest due to the design flexibility, accuracy and reliability, especially for customized manufacturing in medical field . Moreover, the main benefit of 3D printing is the possibility to produce patient-specific structures based on images obtained with computed tomography (CT) or magnetic resonance imaging . Finally, 3D printing technology is green processing technique significantly reducing waste and material consumption . Traditional manufacturing methods such as injection molding and CNC machining typically generate a large amount of scrap material, while 3D printing allows for the precise use of materials, resulting in minimal waste . However, an important limitation of this technique is a resolution of a single printed line limited down to few micrometers. Particularly, when considering fabrication of scaffolds for tissue engineering mimicking the natural fibrous extracellular matrix (ECM) at the nano scale, it becomes necessary to create nano meter-scale structures, such as nano fibers.