The Probe method rolls a sphere over the van der Waals surface of a seed moiety (for which we use the ligand) in order to generate close-contacts. These are classified into different categories depending on the contact distance, with hydrogen bonds as a separate category that also depends on atomic identity. rinrus uses the Probe classifications to assemble a list of residues that come into contact with the seed, at which point users can select the number of residues to include in the model. In the present work, the maximum number of residues suggested was used to construct the Probe models.