A one-way ANOVA was conducted on each of the factors to determine the contribution of each factor to the overall extraction variance. Replicate S/N values for each of the 12 factor/level combinations in the L'9 array served as the input for ANOVA (Supplemental Response Table ). Results for the RP+ ANOVA for the number of features are shown in Supplemental Table , where the degrees of freedom (DF), sum of squares (SS), variance (MS), and percentage Run number (1-9) is shown adjacent to the appropriate set of data points. Detailed information on these experiments can be found in Table .