Before this study, no API existed for the SmartGraph platform that we know of. There exists, however, other platforms with APIs that can be utilized in a network pharmacology setting. The STRING database includes experimental determined and predicted protein-protein (regulatory) interactions. DrugCentral , ChEMBL , PubChem and DrugBank contain drug-target interaction data. The KEGG , Pharos , and RampDB databases include pathway information besides protein targets and small-molecule (drug) interaction data. While these databases are essential sources to build knowledge graphs, such as Neo4COVID19, and Hetionet , from a knowledge mining perspective it is pivotal to have a path search functionality. The only platform that provides such functionality as well as an API is the proprietary Ingenuity Pathways Analysis (IPA) platform.