In recent years, Newton-X became the host of novel methods for nonadiabatic couplings without wavefunctions, zero-point-energy leakage corrections, and nonadiabatic dynamics induced by incoherent light, in complex-valued potential energy surfaces, and including multiple chromophores. All these features, together with interfaces to numerous third-party programs spanning methods from MRCI to machine learning potentials, make Newton-X one of the richest software platforms for mixed quantum-classical simulations. This paper reviews the basic concepts underlying TSH and NEA and all these novel developments, delivering an integrated overview of the Newton-X capabilities.