CUR and PTX loaded formulations were prepared through thin film method, to investigate the chirality influence of ABA triblock copolymers on the solubilization of common model drugs. However, the difference of LC between chiral, racemic triblock copolymers and the 1/1 (w/w) mixtures of two corresponding chiral copolymers is not significant for either CUR or PTX in most cases. However, A-pEtEtOx-A and A-pPrMeOx-A exhibit specific drug loading for CUR and PTX similar to the isomeric pair of A-pBuOx-A and A-pPrOzi-A shown previously. It indicates that shifting a methylene group from the N-