Generating the 27 CRNs (3 surfaces for each of the 9 metals) and running the microkinetic simulations for all the metals and surface orientations took only 8 minutes on a 24-core CPU (3.2 CPU hours). Simulating all species and transition states in the network, adsorbed on diamagnetic (all except Ni) surfaces, with DFT would require at least 11000 CPU hours and 91 kWh (see Supplementary Note 10).