Another crucial aspect is the availability of open software libraries to handle and process chemical information, like the Chemistry Development Kit (CDK) , Indigo , RDKit , or OpenBabel , as well as the recently published Python-based Informatics Kit for Analysing Chemical Units (PIKAChU) . Without these open-source projects, the research community would lack basic tools for programmatically reading, modifying, and processing chemical information. Accordingly, they are fundamental for every researcher in the field of molecular informatics.