The reverse transcriptase domain is known as reverse transcriptase (IPR000477). When retroviral elements, like retroviruses and bacterial retroviruses, copy themselves, they use an RNA template to make DNA that they can insert into the host genome and use to their advantage. An RNA-directed DNA polymerase, also known as reverse aminotransferase (RT), is the enzyme responsible for polymerization. Various mobile elements, such as retrotransposons, retroviruses, group II introns, bacterial msDNA, hepatoviruses, and cauliviruses, contain reverse transcriptases.