Homogenates used for optimisation experiments were prepared from fresh bovine liver sourced from a local butcher. Briefly, 100 g of tissue was homogenised via a food processor with 20 mL of 2% carboxymethylcellulose in water and flash-frozen in liquid nitrogen prior to storage at -80 o C. Kidney of a wild-type mouse (5 month old male) was provided in accordance with the Australian code for care and use as residual tissue from prior animal studies conducted at the university. Following euthanasia via isoflurane, organs including the kidney were collected immediately and were flash-frozen in liquid nitrogen prio to storage at -80 o C.