The MS technique has been widely used in biological science, such as proteomics, metabolomics, and lipidomics, due to its remarkable ability to characterize any molecules . Recent applications of MS in the development of environmental monitoring systems such as single particle aerosol-MS (SPA-MS), single photon ionization-MS (SPI-MS), volatile organic compounds (VOCs) analyzers, and so on, have demonstrated its multipurpose uses . The development of the MS-imaging system is a turning point in the scientific world since it allows for precise medical diagnosis of tumors, cancer, and other diseases by analyzing complex biomolecules . Because the MS approach allows for the direct identification and quantification of analytes of interest, space scientists and technologists are employing MSbased analytical techniques . The National Aeronautics and Space Administration (NASA) employed the MS technique to investigate the Space Shuttles' air quality and propellant leaking as well .