The amount and distribution of variant bioactivity data across individual proteins and variants were analysed in detail. For each protein, the number of variants and bioactivity data points were calculated, as well as the variant bioactivity percentage compared to the totality of the protein's data. Within proteins, variants were ordered from most to least populated in terms of bioactivity data. The relative amount of data in the most populated compared to each of the following variants was calculated by dividing the amount of data in the first variant by the amount of data in the variant of interest.