The recent advances in computer aided synthesis planning (CASP) have made it a promising tool for finding and assessing plausible chemical routes. Accurately finding and assessing chemical routes can help to reduce the time required to find novel drugs and materials . One subset of CASP, called forward prediction, is focused on the problem of predicting reaction outcomes in a forward synthesis manner. Forward prediction is mainly used to assess reaction plausibility and can help rank routes depending on whether they are predicted to be successful or not. This ranking can increase the likelihood of finding efficient routes to produce the target compound.