WF-in-DFT embedding methods based on/related to FDE have benefitted considerably from the PbE strategy, which is, strictly speaking, an orbital-rather than a density-based partitioning. In particular, PbE allows to employ fragmentations cutting through covalent bonds, so that, for instance, active centers and innocent ligands in large transition-metal complexes can be separated. This has motivated strategies for automatizing the selection of the active-orbital set along a reaction path in order to calculate reaction and activation energies. Apart from that, the type of QM methods employed in WF-in-DFT embedding now comprise almost all available correlated electronic-structure methods, including highly correlated ones such as CASPT2, CCSD(T), QMC, DMRG, ASCI, and FCI-QMC.