In their work, Li et al. developed a SERS substrate capable of quali-quantification of PAHs. The strategy followed by the authors was based on to using of HKUST-1 MOF (built from Cu 2+ and 1,3,5-benzenetricarboxylic acid -H3BTC-) as substrate for the electrodeposition of Ag NPs. The advantage of this structure is that upon use, the Ag can be electrochemically removed, together with the adsorbed analytes, regenerating the HKUST-1 substrate and reusing it for a new Ag electrodeposition cycle (see Figure ). The presence of the MOF allowed the device to be stable in a wide range of pH (from 2 to 12), contrary to the behaviour of the bare Ag colloids. The substrates presented also excellent reproducibility, performing with a variation of 8.5% over 50 different substrates. In addition to good stability and reproducibility, the reported SERS substrates were proven to be suitable for on-site simultaneous detection (by using portable Raman spectrometer) of different PAHs, namely anthracene (ANT), pyrene (PYR), Perylene (PER), and 4-chlorobiphenyl (4-CBP) in river, sewage and seawater samples (Figure ) with a performance comparable to GC-MS. While GC-MS provided results with a 4.8% RSD, the HKUST-1-based SERS substrate did it with an 8.1 % RSD, demonstrating the potential of MOF-based SERS substrates towards the development of suitable detection platforms for VOCs. Despite only a handful of analytes are discussed above, many other examples can be found in literature. To name a few, the detection of butanol, isopropanol, chloroform, diphenylamine, pyridine derivatives, aldehydes and acetone was also achieved by MOF-based SERS substrates. As previously mentioned, different figures of merit are available to benchmark the analytical performance and Table provides a short summary of the data compiled in our dataset. LOD reached by the different substrates are summarized and confronted with relevant concentrations in the field of environmental and industrial monitoring.