In the typical virtual screenings performed in our group, we generate either 50 docked poses per ligand with AD-GPU or an average of 6 docked poses per ligand with Vina, often with one target residue modeled as flexible (e.g.: reactive docking ). These numbers balloon the total size of the final docked results to more than 100M for AD-GPU or ∼12 M for Vina. Eventually, filtering and post-processing steps must be applied to reduce these results by 5 or more orders of magnitude to make them suitable for visual inspection (Figure ).