The individual isomers of ACC-1 were subsequently separated by HPLC, and their individual UV-Vis spectra obtained accordingly. Analysis of the photoisomers of ACC-1 by 1 H NMR spectroscopy enabled determination of their thermal half-lives, indicating a comparatively stable EZZ-isomer. The photoisomerizability of these cages was also supported by relative energy calculations, further demonstrating that computational design can be used to tackle this problem. These photoswitching experiments were carried out in solution; future work will focus on discovering functional porous organic cage materials that can be switched in the solid state.