Utilizing surfactants, like Brij, is an efficient, quick, and biocompatible method which may improve DT's solubility, stability, and bioavailability . Moreover, polymer-based micelles provide tailored drug administration by regulating the release profile of the entrapped molecules in response to a particular stimuli like pH or temperature . These traits of micelles can enhance drug penetration, delivery retention and drug accumulation at target sites for improved therapeutic outcomes . From different literatures it was understood that some research on the DT's stability was done previously . However, utilization of non-ionic polymer based micellization process to increase the stability of DT at ambient room temperature and study of DT's sustained release profiling from the micellized core is still inadequate. Moreover, a proper toxicological analysis of DT is scarce for promoting its application in commercial biopharmaceutical products. Therefore, in this research work, an attempt was made to formulate a delivery vehicle system for DT based on Brij (S20 and 58) micelle. The micelle-DT conjugate system increases the DT's shelf life and reduce its spontaneous degradation. Assessments were made of the effects of environmental variables on DT within the micelle, including temperature and pH.