The development of liquid crystal-based quantum computing systems faces several technological obstacles in material synthesis and fabrication. First, the physical aspect involved in these systems proves to be a tough technological nut to crack and would require a deep insight into quantum mechanics and materials science to completely explain. Significant progress has been made in several physical implementations of quantum computing, but a true breakthrough has yet to be realized in any one approach. Designing a system that can effectively shield itself from influences while remaining manageable for executing logical quantum operations and facilitating measurements poses a major hurdle . Quantum computing requires storing quantum information in a set of two-level systems, processing this information using quantum gates, and a means of final readout. Technologies based on quantum optical and solid-state systems are among the most advanced candidates. However, accurate quantum control of the coherent evolution is necessary to implement gate operations while avoiding decoherence The strict standards require the development of materials and tools used in crystal-based quantum computing. Advancements in superconducting materials, van der Waals materials, and moiré quantum matter offer hope for various quantum technologies, including quantum computing . Combining crystals with materials employed in quantum computing systems poses challenges . This involves ensuring compatibility to avoid disruptions in the characteristics of liquid crystals. Establishing an interface between liquid crystals and substrates, like silicon or graphene, requires innovative manufacturing techniques and thorough material analysis . Another challenge is preserving the uniformity of liquid crystal phases under changing external circumstances, such as temperature and pressure. The purity of the starting ingredients and the presence of contaminants can significantly affect the performance and dependability of the liquid crystals, complicating the synthesis process . On the other side, fabricating devices that use liquid crystals for quantum computing involves numerous technical challenges. One major challenge is the perfect alignment of liquid crystal molecules, which is critical for peak device performance. Traditional approaches, such as rubbing or photo alignment, have limitations in scalability and homogeneity, often resulting in flaws that might reduce device efficiency . Furthermore, integrating liquid crystal materials into current quantum computing architecture, such as superconducting qubits or photonic circuits, necessitates sophisticated fabrication procedures. It is challenging to ensure the stability of liquid crystals within these devices, mainly when operating under low temperatures and electromagnetic fields . The fabrication process must, additionally, include liquid crystal encapsulation to prevent contamination and degradation over time. This encapsulation entails creating strong encapsulation materials and processes that do not interfere with the liquid crystal's optical and electrical capabilities. Scaling up the fabrication process for mass production while maintaining device quality and performance remains a significant challenge. Each stage of the fabrication process, from material deposition to patterning and assembly, must be precisely optimized to achieve reproducibility and high yields . To tackle these challenges, researchers need to collaborate across fields such as materials science, chemistry, physics, and engineering. Progress in nanofabrication techniques, comprehension of liquid crystal behaviors at a quantum scale, and creative synthesis approaches will play key roles in surmounting these obstacles. The ongoing drive for innovation and teamwork across disciplines is anticipated to speed up the advancement of quantum computing technology based on crystals.