The HELAO-async implementation described herein is intended to be agnostic with respect to the type of Operator and Observer, which may involve any combination of a human researcher, an autonomous operator selecting experiments via an AI-based acquisition function, or a more general broker for coordinating experiments across many workflows. The scope of an Orchestrator is that of a single workflow, and by implementing each Orchestrator as a FastAPI server, the parameterized workflow is exposed to the Operator via custom FastAPI endpoints. Fig. also depicts Observers, which can subscribe to the FastAPI websockets established by an Orchestrator and/or Action Server. Each Orchestrator and Action Server must be programmed to publish data of interest to websockets, which enables any number of Observers to listen-in as needed. Our common implementation to-date is a web browser-based Observer (a.k.a. Visualizer) that researchers can launch to monitor quasi-real-time data streams, a critical capability for experiment quality control.