We have described in this paper a simple strategy for enhancing the release performance from ZrNT via structural modification. The modification involves the fabrication of a double-layered structure with a varying diameter, namely the top layer with a smaller diameter that opens into a second layer with a larger diameter, achieved by voltage alteration during anodization. We found out that by changing the voltage from 20 v to 90 v the diameter along the tube length increases from 30 nm ± 5 nm to 80 nm ± 20 nm. The result from the drug release studies indicates that the unwanted initial release was reduced by 74 % when compared with the constant diameter equivalent structure and the release time was extended by 143 %. This improved release behavior in terms of initial burst release, and an extended retention time indicates that the modulated double-layer structure demonstrated superior performance in the role as, delivery platform for implant systems. Conclusively, we