The assumption of Research Use Exemption should apply to US academics but the position of commercial institutions is less clear. Note, however, despite the detailed data package in the opnMe portal, the absence of a publication (BI-1046 is PubMednegative but has over 40 false positives in Google Scholar because of an HIV clinical trial designation BI 1046) means that CID 146293963 has neither ChEMBL nor BioAssay links.