For Chignolin, both t 2 and the corresponding relaxation process for different hyperparameters trials are similar, as can be seen by inspection of the models 1 and 2 (ranked 1 and 4 respectively in Figure , see Table and sections S2.1 and S2.2 for more detailed information on each model). In model 1, Figure (a), shows ψ 2 as an unfolded-folded transition.