After developing a strategy for automating the experimental workflow via a robotic platform along with an algorithmic strategy for controlling the addition of acid/base separately, we then aimed to merge both efforts. Using Flab, the control code of the liquid handling robot allows direct interaction with the algorithmic pH adjustment strategy -the measured data is directly used for ML surrogate model training. The results of the subsequent decision making (next conditions to evaluate experimentally) is passed to the liquid handling robot. The adjustment process and decision making can be monitored in real-time, as shown in Figure .