A series of recent experiments have demonstrated that chemical reaction rate constants can be enhanced or suppressed by coupling molecular vibrations to quantized radiation modes inside an optical microcavity. These surprising modifications happened under a "dark" condition without any external laser pumping, and the change in the chemical kinetics is attributed to the formation of vibrational polaritons (quasiparticles from the hybridization of the photonic and vibrational excitation) . This phenomenon is referred to as the vibrational strong coupling (VSC) modified chemical reactivities, whose central feature is that when the cavity frequency ω c is in resonance with the bond vibration frequency ω 0 , the reaction rate constant can be enhanced or suppressed, usually up to 4-5 times compared to outside cavity rate constant . This new strategy of VSC provides a novel avenue for synthetic chemistry through cavity-enabled bond-selective chemical transformations as one can selectively slow down one competing reaction over the target reactions by using cavities .