The polarizable embedding (PE) model is an advanced fragment-based quantum-classical embedding scheme where mutual polarization effects are taken explicitly into account in a fully self-consistent manner. The environment is described in terms of distributed multipoles and polarizabilities, both of which are derived from quantum-mechanical calculations on the individual fragments that make up the environment. Extensive analysis in previous works have shown that such an approach gives high accuracy when using LoProp-based atom-centered multipoles up to and including quadrupoles to describe the permanent charge distribution of fragments in the environment, and atom-centered anisotropic dipole-dipole polarizabilities to describe polarization effects.