Among the structures, the Myeloid cell leukemia 1 protein (PDB ID: 4HW3) showed the lowest correlation coefficient of 0.18. However, the dynamics of the protein may be still reasonable due to the following reason. The original protein from the PDB entry is a multimer, but only the biological unit of the protein, which is a monomer, was chosen to do the simulations. (Figure ). In this altered environment, transitioning from protein-protein interactions to a solvent-based context, the protein's dynamic behavior may be altered.