On the other hand, another pandemic i.e. Influenza virus infection is characterized by minor respiratory issues. However, in some severe scenarios, it might lead to complications in various organs of the body resulting in death which poses a global threat and emergency. China with a large population has a larger number of cases of influenza leading to deaths . Moreover, scientists have also targeted ACE2 receptor to find out the solution for COVID-19 as it is involved in SARS-CoV 2's entry and replication . Several GPCR signaling pathways have a significant contribution in the viral life cycle which might be targeted for anti-viral treatments. Furthermore, several GPCRs including adhesion GPCRs also contribute to immunology and viral infections . Beyond that, cellular kinases P a g e 5 | 56 include PI3K, FAK, and ERK. p38 MAPK, JNK, and IKK are involved in viral entry, replication, and sensing .