Among the diverse array of NPs, terpenoids are particularly prevalent in marine invertebrates . Notably, cembrane, eunicellane, and biflorane (serrulatane) diterpenoids emerge as primary types commonly extracted from corals (Fig. ) . Cembrane diterpenoids, with their distinctive 14-membered ring structure, represent the largest group of coral-derived diterpenoids, boasting over 1200 individual compounds , including the neuromuscular toxin lophotoxin . Eunicellane diterpenoids, characterized by their unique 6,10-bicyclic skeleton, include more than 400 compounds , such as the potent anticancer agent eleutherobin. Similarly, biflorane diterpenoids, known for their 6,6-bicyclic structure and a prenyl tail, comprise over 290 identified compounds . These terpenoids are renowned for their diverse biological activities; for example, pseudopterosin A from corals exhibits anti-inflammatory and analgesic effects , while kalihinol A from sponges is noted for its antimalarial properties .