The OmniFire is a Swiss Cat+ in-house development based on the Agilent RapidFire. This equipment (Figure ) is designed to serve a number of functions. Initially, it is intended to act as a high-throughput fraction collector in conjunction with an Agilent 1260 Preparative HPLC. Subsequently, it is to be employed as a sample preparator, filler, and sealer for NMR 96 x 1.7 mm tubes racks. Finally, it is to be utilized as a sample injector for in-line Agilent UV Cary 60 and Bruker FT-IR Invenio. In addition, the apparatus serves as a sample Dispatcher for an Agilent 6550 IM-Q-TOF coupled to an Agilent 1260 SFC and the NMR racks. Moreover, the instrument must interact with a series of Agilent Bravo liquid handlers for sample preparation and solvent exchanges, which are necessary for the solid-phase extraction (SPE) steps. This equipment plays a pivotal role in the global Swiss Cat+ automation scheme, particularly in the automated characterization of high-resolution compounds. The functions of the instrument are described in the functional high-level workflow presented in Workflow 2. As illustrated in Figure , the OmniFire consists of two ensembles of valves associated with cartesian positioning systems (5 and 7), two previously mentioned spectrophotometers Agilent Cary 60 UV-VIS ( ) and Bruker Invenio FT-IR (9). Additionally, the apparatus comprises an ensemble of sample management devices, including a sixaxis Universal Robot 5e (1), a Brooks Scara robot PreciseFlex 3400 (3), an Agilent SBS plate sealer (not visible), and a 3D printer head utilized for sealing the NMR tubes (included in 5). All valves and cartesian positioning systems are operated via a Beckhoff controller, which is not visible and forms the entirety of the "Dispatcher" system. Furthermore, the mobile robot (EM) utilized for sample transfer is visible on top, identified as number 2.