Briefly, a peptide mapping analysis experiment was created in BioPharma Finder™ (BPF) version 4.1 (Thermo Scientific, San Jose, CA, USA) to process the raw data files generated from Section 2.6 using the parameters summarized in Table . Only peptides with a ≥ 95% confidence score, ≥ 1 x 10 5 average MS area, and within ± 5 ppm mass accuracy were included for sequence coverage evaluation.