To select the representative aerobic oxidation, the reaction conditions to oxidize 4methoxybenzyl alcohol (1a) were screened (Table ). The oxidized product panisaldehyde (2a) is a valuable substance in food chemistry and a valuable intermediate for synthesizing active pharmaceutical ingredients . This oxidation has been often applied for evaluating catalyst activity for aerobic oxidation , and its screening results can be transferred to obtain a wide variety of benzaldehydes from benzyl alcohols. The screening was conducted under batch conditions. Toward its application to continuous flow synthesis, we considered the description of reaction mixture as well as the reaction rate, conversion, yield and availability of the catalysts.