MESP gives the most suitable way to recognizes the receptor of a drug molecule. The MESP analysis allows for a comprehensive examination of a drug molecule's total charge distribution, dipole moment, electronegativity, and partial charges, enabling to explore the relationship between molecular structure and physiochemical properties, paving the way for advancements in the development of new biomolecules and pharmaceutical drugs. MESP is used to identify the reactive areas of molecules that can be used as anti-cancer, anti-fungal, anti-microbial, anti-bacterial, anti-malarial, anti-migraine, anti-tumor, anti-tubercular, anti-viral and anti-inflammatory.