To demonstrate the optimization of the PEDOT:PSS ink, we evaluated the influence of three major components, the conductive polymer network (PEDOT:PSS), the thickening agent or rheological modifier (Methylcellulose, MC), and the crosslinker (N,N′-Methylenebis(acrylamide), BIS), on printing behavior and properties resulting hydrogel (Figure ). Using various concentrations of these components compared to a single reference ink, we assess the ink's rheological properties, the ink's printability, the hydrogel's mechanical properties, and the hydrogel's conductivity. Rheological measurements of the inks contribute to an ongoing effort to establish standardized characterization methods in the field of soft material extrusion printing. Because soft devices have wide ranging applications, from wearable devices to environmental sensors, the ability to tune material properties according to the application is essential for widely applicable fabrication methods. This thorough assessment of factors that can be optimized throughout the fabrication process facilitates more widespread adoption of extrusion printing for iontronics.