For the small magnitude pair of hfcs ( 55 Mn3 and 55 Mn4), two prominent single quantum EDNMR transition frequencies are expected for each coupling, given by υ 55 Mn ± 3|A| and υ 55 Mn ± 2|A| with the + orcorresponding to positive or negative hfc values respectively. The small negative values of the hfcs as calculated by our BS-DFT calculations, Table , result in the simulation of spectral peaks of low intensity that lie in a region of the spectrum overlapping and obscured by the central blind spot of the EDNMR experiment. The shape of the central blind spot and experimental background will be greatly affected by B1 inhomogeneities. Consequently, post-processing approximations may distort the experimental data, particularly in the low frequency region. The inhomogeneity of the B1 field at different offset frequencies will further affect the experimental background and relative intensities of the spectral peaks at different frequencies, particularly around the maximum of the B1 field, where changes in B1 are largest with respect to changes in offset frequency. Such uncertainties may explain the nonobservance of the EDNMR bands below ~ 60 MHz in the W-band (94 GHz) spectra for the methanol treated samples, as the relative ratio of these peaks to the more well-defined signals at ca. 150 MHz depends on the bandwidth of the resonator. Finally, the simulations presented here do not consider multi-quantum transitions (MQTs) involving more than one Mn nucleus. These have more impact