The results from the pipeline for the AAE-128, Transformer-128 and WAE-128 presented in the supplementary figures (Fig. . S8) show that by locking PC's of interest and sampling nearby points along other PC's we can generate novel peptides that have similar properties to the original GL13K. While some generated samples feature drastic changes in certain properties such as the fourth peptide from the AAE-128 with a charge of 1 at pH 11 or both generated peptides with -1 charges at pH 11 for the Transformer-128 and WAE-128 models, most properties fall near the original GL13K sequence properties.