The excellent performance of LC-PBE is explained by the accurate electronic structures for zwitterionic compounds predicted with range-separated functionals. This point is particularly relevant since not only does ozone exhibit partly zwitterionic character, but also many products of the reaction network are zwitterions. Considering that standard quantum chemistry methods (PBE and PBE0) failed to locate the TS and that semiempirical methods are persistently inaccurate for complex bond-breaking processes, we employed LC-PBE for finding and optimizing the molecular structures in our CRN explorations.