Every complex studied here, except for one where no NOEs at all were observed, has NOEs between at least one aromatic guest proton (G1-G9 in Figure . Numbering of atoms used to identify NOEs in Tables ) and the hydrogen of the CD's H3 carbon (H3 in Figure . Numbering of atoms used to identify NOEs in Tables .) Thus, in all cases, at least part of the phenothiazine moiety is at the secondary face of the CD. In most complexes, there are also NOEs between aromatic guest protons and the CD's H5, signifying that part of the phenothiazine moiety penetrates deep into the host's cavity. The drugs TDZ and TFP show additional NOEs that involve the cationic ends of their side-chains. These NOEs consistently involve H6 or HMe1 on the host, meaning that the cationic side chains lie at the primary face of the hosts. We conjecture that the cationic side chains of all of the phenothiazines studied here reside at the primary face, but that only the relatively bulky side-chains of TDZ and TFP are sufficiently locked in to generate observable NOEs. Table . Observed NOEs in phenothiazine-βCD complexes. Atom notation is provided in Figure .