The amino alcohol (0.25 mmol) was dissolved in 0.5 mL of H 2 O and the pH of the solution was adjusted to 9.5. 10:0 lyso G>P (0.025 mmol) was then added and the pH was readjusted to 9.5. The mixture was transferred to a 30 mm diameter glass Petri dish and the H 2 O was allowed to evaporate in the fume hood draught at room temperature (22°C) until a dry film was obtained (this process was always complete within 4 hours). The film was then heated at 80°C, unless otherwise stated, for 24, 48, 72, or 96 hours. For analysis by P -NMR, the film was dissolved in 0.5 mL of 0.1 M Triton X-100 in H 2 O:D 2 O (9:1, v/v).