We presented and experimentally validated a high-throughput computaVonal workflow to idenVfy potenVal candidate pore carrier/solvent PL combinaVons, as exemplified with type II POC-based PLs. At each step of the workflow, we idenVfied several features contribuVng to the performance of the PLs designed using the scrambled 3 3 :13 -R POC mixture and demonstrated the applicability of these computaVonal techniques to POC-based type II PL design.