Simulating crystallization using MD, especially crystal nucleation, presents a significant challenge due to the infrequency of many of the atomic and molecular scale elementary steps required for these processes to occur. For instance, depending upon the thermodynamic state of the parent phase, crystal nucleation can occur on time scales typically orders of magnitude larger than those accessible to brute-force simulations . The separation of these timescales has made stimulating crystallization an ideal playground for the development of enhanced sampling methods based on MD. Thanks to enhanced sampling, significant early progress was made to analyze the early stages of crystallization in simple systems of uniform particles and towards the in-depth investigation of nucleation in monocomponent molecular systems, such as pure water . In recent years, an evolution towards systems with increased complexity and practical relevance has begun, enabling e.g., the study of solute precipitate nucleation. These tend to focus on model systems , such as two-component Potts-lattice models, or inorganic systems such as NaCl(aq) . Attempts to simulate organic solids nucleating from solution have been successful in highlighting the structural features of early-stage crystallization precursors and to extract qualitative information on nucleation mechanisms. Origin of the timescale separation in nucleation: Nucleation Free Energy Barriers and Classical Nucleation Theory.