One of the most significant trends in ART is the integration of advanced genetic screening techniques. Preimplantation genetic testing (PGT) has become increasingly sophisticated, allowing for the detection of chromosomal abnormalities and single-gene disorders in embryos before implantation. PGT-A (aneuploidy screening) technique screens for chromosomal abnormalities, which are a leading cause of implantation failure and miscarriage. Advances in nextgeneration sequencing (NGS) have improved the accuracy and efficiency of PGT-A, leading to higher success rates in IVF cycles. PGT-M (monogenic disorders) is used to identify embryos carrying specific genetic mutations, enabling couples with hereditary conditions to have healthy offspring. The development of CRISPR-Cas9 and other gene-editing tools has further enhanced the potential for correcting genetic defects at the embryonic stage. PGT-SR (structural rearrangements) form of testing is designed for individuals with chromosomal translocations or inversions, helping to identify embryos with balanced chromosomal structures. These advancements not only improve the likelihood of a successful pregnancy but also reduce the risk of passing on genetic disorders, offering a more personalized approach to reproductive medicine.