To establish the competency of anthracene as a photoredox catalyst, selected CV experiments were conducted (see Table and the ESI for further details): Weinreb amide 1a (E 0 1/2 = -1.90 V vs SCE) was selected as a model substrate for the reduction to secondary amide 2a. Preliminary validation was established by performing the reaction with 5 mol% anthracene in acetonitrile under irradiation at 365 nm for 1 h, which furnished product 2a in 53% yield on a 0.1 mmol scale (Table , entry 1). The introduction of additives enabled the yield to be further enhanced (entries 2-5). Whereas the addition of cyclohexadiene (CHD) and K2CO3 led to a modest improvement (entry 2, 69%), 2,2,6,6-tetramethylpiperidine (TMP) proved to be detrimental (entry 3, 48%). Triethylamine had a very positive impact on reaction efficiency (entry 4, 89%) and diisopropylethylamine (DIPEA) enabled the quantitative conversion of 1a to 2a. Control reactions in the absence of anthracene (entry 6) or irradiation (entry 7) completely suppressed N-O bond cleavage.