Given the evidence of beam-induced reorientations from diffraction series on beam-sensitive crystals, we hypothesized they might coincide with changes in diffraction contrast observable in real-space images of the illuminated crystals. To investigate this, we illuminated stationary crystals with the same flux used for diffraction measurements, while acquiring fast image series. At room temperature, crystals of biotin, Co(II)-porphyrin, and Zn(II)-methionine showed clear bend contours across their bodies (Fig. ), evidence of deformation visible as bands of differential contrast upon a crystal . These contours moved unpredictably in response to electron beam exposure, but appeared to diminish in amplitude with increasing fluence. When illuminating crystals of biotin, we consistently measured bend contour migration that was greatest within the first 0.5 e -/Å 2 of exposure, and largely settled by or shortly after the delivery of 1.0 e -/Å 2 total fluence (Fig. , Supplementary movie 6). In crystals of Zn(II)-methionine, the snap-like lattice change we discussed in earlier sections was corroborated by a rapid change in the position and appearance of bend contours in the crystal, which rippled and migrated rapidly, then abruptly vanished, succeeded by many less prominent, more slowly rippling contours (Fig. , Supplementary movie 7). Crystals of Co(II)-porphyrin, interestingly, also hosted bend contours readily visible by imaging, but were distinctly static except in response to much higher electron flux (Fig , Supplementary movie 8). Notably, for each compound tested, the pattern of dynamism in bend contour motion matched the degree of lattice reorientation observed in diffraction patterns from the same illuminated area of the crystal. This further cemented the idea that bend contour motion and non-monotonic changes in diffraction intensities are complementary observations of the same underlying reciprocal lattice rearrangement occurring within molecular crystals as they are irradiated by an electron beam.