We experimentally evaluate the method for adapting MPO in a task of generating molecules with a high QED-score , based on scoring components of physicochemical properties. We chose QED-score as the goal because it is inspired by how humans evaluate the drug-likeness of molecules. This makes it a suitable proxy to simulate a chemist's intuition and, furthermore, there exists a publicly available method for approximating it . We make a minor modification to the standard QED score, so that the modified score 𝑆 𝑚𝑄𝐸𝐷 (𝑥) ∈ [0,1] favors smaller values of partition coefficient (logP), to make the task more difficult a priori (for the details of the modification of the desired value of logP from the original average 3 to average 1.5, see Supplementary material Section 2.1).