FMOPhore can be used to assess binding interactions in holo-complex scenario (cocrystalized protein-ligand structure). In cases of multiple co-crystalized ligands against the same target, it can construct a quantitative-structure activity relationship model (Q-SAR). The QSAR model is represented in 2D and 3D-heatmaps, with FP-score quadrant matrix plot to classify binding site residues. FMOPhore can also be combined with postdocking analysis to assess ligand-protein binding pose, quantifying the interaction energy and the protein-ligand pharmacophoric features.