Accuracy based performance metrics, such as RMSE and MAE, are more appropriate than correlation-based statistics to evaluate methods because of the small dynamic range of experimental log P values (0.6-3.0). This is usually reflected in the confidence intervals on these metrics. Calculated error statistics of all methods can be found in Tables , and S4. Summary statistics were calculated for each submission for method comparison. Details of the analysis and scripts are preserved on the SAMPL7 GitHub repository (described in the "Code and data availability" section).