Finally, we challenge our method to explore a highly complex catalytic system under realistic operando conditions. We applied Loxodynamics to a reaction occurring at the Brønsted acid site (BAS) of a zeolite. Here, we focus on the dehydration of ethanol to ethylene at the BAS of acidic chabazite (H-CHA), a widely used zeolite, a complex reaction, and highly relevant for the chemical industry.