Materials and methods. Samples of CBN-OAc and CBD-OAc2 were synthesized by Dr. Rob Jensen and supplied by FloraWorks TM . The CBN-OAc (99%) CBD-(OAc)2 (95%) were used as received. A commercial formulation containing ∆ 8 -THC-OAc was purchased from Hydro-Hemp in a pre-packaged SICKO TM brand vape cartridge and used at 10 W. Analysis of the commercial sample was performed using a capillary GC column mounted in an Agilent (Santa Clara, CA) 7890A GC interfaced to an Agilent 5975C MS, and operated in electron impact ionization mode. The sample contained approximately equimolar amounts of Δ 8 -THC-OAc and Δ 8 -THC, in addition to terpenes. Nuclear Magnetic Resonance (NMR) spectra for all dabbed/vaped acetate samples were acquired on a Bruker Avance III 600 MHz NMR spectrometer at 128 or 256 scans, 16 s relaxation delay for qNMR samples, 30-degree flip angle acquisition. Methyl 3,5-dinitrobenzoate was used as the qNMR internal standard. Dabbing experiments. An electronic nail ("e-nail") was used in the dabbing experiments (EKS REX-C100 controller). The e-nail consists of a metal wire that is wrapped numerous times around the quartz nail and connected to the power source. Temperatures for dabbing experiments were set at 500 °C initially to screen for the presence of reacted ketene as N-benzylacetamide. For quantitative studies the e-nail temperature was set to 378 °C, consistent with our prior dabbing studies based on a survey of social media showing a range of preferred e-nail user temperatures of 340 -482 ⁰C. Tygon tubing (1/4") connected the dab rig to an impinger that was connected to an SCSM-STEP Smoking Machine (CH Technologies). The impinger was filled with CDCl3 (2 mL) for NMR analysis. Additionally, 150 µl of benzylamine (ketene trapping agent) and 100 µl of the internal standard for NMR (methyl 3,5dinitrobenzoate) were included in the impinger. Trials were run using a modified version of the CORESTA protocol at a puff depth set at 1.32 and a draw time of 4.8 s, with 30 s between draws.