Another material with associated software is the Promega 6x5 spike-in which can be used along Some tools, such as those in the TVT series, require data to be uploaded to a server. This is convenient, as it can be done from data acquisition computers without the need to install additional software, and results can be viewed in a web browser, as long as the computers are connected to the Internet. For labs operating under tighter security or where data privacy is of concern, most of the above software can be installed and run on computers not directly connected to the internet. We note that data from QC samples interspersed with experimental samples may contain carry-over from those samples, especially when running immediately after a sample. Though this could be used as an unintentional QC metric (i.e., abundant peptides from experiment could be tracked in QC samples), more critically is that the privacy and security concerns that apply to the experimental samples therefore apply to the raw data from the QC samples.