The hundreds of top-children predicted different conformers with variations in their molecular atoms and/or rings, but maintaining only two main scaffolds (representative top-children IDs 35399 and 4566). In this work, the topchildren defined by ordering by their ADV affinities predicted the main 35399 scaffold, however, similarly to what was commented above for different conformers, the secondary 4566 scaffold could also experimentally show antifusion properties. Supporting Materials -89VHSValignement.docx. gpGVHSV from 89 amino acid sequences of different isolates from diverse sources were aligned by Clone Manager vs9. The 67 EFEDIN and 302 LNHLIT amino acid sequences around the R4-linker and the TrD were in bold red letters. Only one (I71T) or three (N203G) mutations (isolates in red), respectively were detected.