The brodifacoum docking cavity was transferred by alignment of the crystallographic brodifacoum-human VKORC1 model 9 to each of the rat VKORC1 wild-type and mutant models by PyMol. The resulting pdb files contained the VKORC1 ATOMS (TER) line followed by HETATM brodifacoum lines(END). The CONECT lines were removed from the pdb files for the DW subprograms.