Radial distribution function (rdf) (g(r)) provides insights on the average picture of the distribution of the constituents in the systems considered. This is calculated with the in-built module of GROMACS. In this investigation, we are mainly interested in structural aspects of water in the aqueous solution of reline, e.g. its self-distribution and also the distribution of urea and bulky choline molecules around the water-oxygen atoms (Ow). g(r) of water-oxygen (Ow), urea and, choline around water-oxygen (Ow) is represented in Fig