At least two different approaches to the F-Test are mentioned in the literature (a) the Weakened Grid Search (WGS) and (b) Model Comparison (MOC). 11,43 Keller at al. published an Excel-Guide to apply the F-Test to Michaelis-Menten Kinetics using the Weakened Grid Search. SupraFit provides both approaches to the F-Test, that will now be introduced: