That prior work suggests that predictive detailed modeling can be the key to reaching a scientific consensus on fouling fundamentals. Impurities can greatly impact the fouling chemistry. One of the most prevailing impurities is traces of dissolved oxygen in the unit fluid, which can enter the process as an impurity along with the feedstock, water used for quenching, or additives. Literature experimental investigations have shown that dissolved oxygen can affect fouling significantly, where dissolved oxygen was measured to accelerate fouling even at ppm level concentrations, while the fouling rate becomes independent of oxygen concentration near air-saturation. The effects of dissolved oxygen on fouling rates were recently measured using Quartz Crystal Microbalance with Dissipation monitoring (QCM-D), similar to the prediction by our detailed fouling model for QCM-D cell fouling. It is generally accepted that oxygen affects fouling through autoxidation. Autoxidation is a process where dissolved oxygen combines with ordinary radicals formed from reactions between unsaturated hydrocarbons, transforming into peroxyl radicals. The peroxyl radicals then propagate with additional monomers and dissolved oxygens and become polyperoxides, which eventually become oxygenated deposits. For certain monomers, the autoxidation forms peroxyl radicals that are more reactive than the ordinary radicals, accelerating the fouling process. However, the relative rates of fouling contributed by ordinary radical polymerization and autoxidation depend on the specific fouling monomers involved.