3,4,5-Trimethoxy ring-substituted ethyl phenylcyanoacrylate is reported in synthesis, antimicrobial and antitumor study of new pyrido[2,1-a]isoquinolines ; in synthesis and study of functionalized UiO-66 MOF for turn-on fluorescence sensing of superoxide in water ; in K3PO4-promoted cyclopropanation of electron-deficient alkenes with 2-bromo-1,3-propanedione compounds ; in synthesis of thiazacridine derivatives as anticancer agents against breast and hematopoietic neoplastic cells ; in synthesis of pyranoquinoline derivatives catalyzed by piperidine ; in synthesis of 2-oxazolines from ethyl αcyanocinnamate derivatives with N-bromoacetamide ; in synthesis, in vitro anticancer activity and in silico study of new disubstituted thiazolidinedione derivatives ; in synthesis of 2-oxazolines from ethyl α-cyanocinnamate derivatives with acetamide and Nbromosuccinimide ; in regio-and stereo-selective synthesis of spiro pyrrolidine and pyrrolizidine derivatives ; in synthesis and reactions of (Z)-2-imino-5-(3,4,5trimethoxybenzylidene)thiazolidin-4(H)-one ; in studies of antifungal potential of ethyl benzalcyanoacetate and its C-phenyl derivatives . 2,4,5-Trimethoxy ring-substituted ethyl phenylcyanoacrylate was reported in studies of antitumor activity of novel pyridine, thiophene and thiazole derivatives ; in synthesis of such hydroxytryptamines as bufotenine, 6-hydroxybufotenine, and serotonin . 2,3,4-Trimethoxy ring-substituted ethyl phenylcyanoacrylate was involved in synthesis and biological screening of some novel 3-amino-4-arylidene-5-pyrazolones and thiazolo[3,2-a]pyrimidines , in synthesis of some new chromones and flavones and its utilization for the synthesis of potentially antitumorigenic polycyclic chromones and flavones , as well as in preparation of phenylcycloalkanes and -cycloalkenes as herbicides .