To date, approximately 450 articles on EME have been published, exploring fundamentals, methods, and applications, which are summarized in recent reviews . Example applications include extraction of metals and heavy metals , peptides , pharmaceuticals , and endogenous metabolites . This has been realized in different technical formats, such as hollow-fibre , 96-well , and various microfluidic formats , all of which have been laboratory-built, and transfer and reproducibility of methods between laboratories has thus been challenging. In 2022, the first commercial EME equipment was however launched, based on using conductive vials to house the sample and acceptor solution . Since then, this vial-based format has been applied for EME in therapeutic drug monitoring (TDM) and analysis of drugs-ofabuse .