The approximately 10,000 compounds in the HSPiP database were subsequently ranked according to their calculated Ra (likelihood to solubilise the POC mixture), with 2147 potenVal new solvents idenVfied (Figure ). However, not all these candidates would be suitable as a PL solvent -in addiVon to needing to be size-excluded to ensure permanent porosity is maintained in the liquid state (addressed in the next stage of the workflow), it would also be beneficial for solvents to: (i) have a high boiling point to reduce volaVlity issues and to enable potenVal temperature-swing gas uptake/release cycles; (ii) have a relaVvely low melVng point so that they are in the liquid state at, or near, room temperature; (iii) not have compeVng reacVvity with the POC imine bonds due to their reversible nature; (iv) be less hazardous than some of those used previously (i.e., avoid chlorinated solvents where possible); and (v) be affordable, which is especially important when considering scale-up. Thus, we implemented and applied a series of selecVon criteria as a screening procedure to the top 100 ranked solute compounds predicted by HSPiP (Figure , Table ). StarVng with the closest match based on Ra and working progressively down the predicted solvents, the following selecVon criteria were therefore applied: