Out of the 30 participant submissions in SAMPL7, 7 were for TrimerTrip, 16 for the GDCCs, and 9 for the CD derivatives. The TrimerTrip submissions included 3 ranked and 4 non-ranked, GDCCs included 4 ranked and 12 non-ranked, and CD-derivatives had 3 ranked and 6 non-ranked (Figure ). For a large portion of methods submitted, docking was used to obtain starting structures, and one submission used self association molecular dynamics (SA-MD) . General classical fixed charge force fields were commonly used, as has become common in SAMPL host-guest challenges (see Section 6.1.2 for methods submitted to SAMPL7 host-guest challenge). Alchemical free energy techniques were employed in many cases, with analysis done via thermodynamic integration (TI) and Bennett acceptance ratio (BAR) for equilibrium calculations. Nonequilibrium approaches were also employed, such as using the fast switching double annihilation method (FSDAM) approach . Here we introduce the results for all ranked methods separated by host-guest system dataset, give statistics for binding of individual host-guest systems averaged across methods, and lastly examine analysis of non-ranked methods including our own reference calculations.