Although eight different SubPc derivatives were used to form seven different assembly patterns, the physical properties of the molecules remained similar. Therefore, the developed systems are ideal for studying the quantitative correlation between symmetry and property. Furthermore, we unveiled the universal guiding principle that circular-and bowl-shaped πconjugated molecules preferred to assemble into closed-packed-like structures, enabling the prediction of resultant assembled structures. Despite the large number of studies on the relationship between molecular structure and its packing, there remains a dearth of reports that have led to the point of proposing universal guiding principles. The crystals and design