Figure shows examples of visualizations of chemical space using various structural representations for multiple purposes. For example, Figure illustrates the use of constellation plots developed in our group to explore the SAR of compounds with analgesic and sedative effects from independent datasets, and Figure illustrates a chemical space based on ECFP4 fingerprints. Both cases remark on their utility to fuse concepts applied in chemoinformatics (like chemical space) to explore biological/clinical data and to generate intuitive SAR representations for informaticians, chemists, pharmacologists, or clinicians. ECFP4 fingerprint. The plot shows 390 data points, each one representing a unique molecule. The data points' shape represents their associated activity, and the color around each data point represents their activity expressed in percentage; The dataset of compounds only contains activities expressed in percentage, from the 100 queries with the higher number of reported compounds. All data was collected automatically from ChEMBL v.34 database , and the KNIME protocols used to construct the constellation plot are available in the supplementary material section. The interactive visualizations were generated with DataWarrior software .