Their synthesis and assembly dominates energy consumption in living organisms and are subjected to strict quality control mechanisms. In bacteria, the three ribosomal RNAs (rRNAs)-16S, 23S, and 5S-are initially produced as a single long polynucleotide (pre-30S), which then goes through a series of maturation steps to form a fully functional ribosome ribonucleoprotein particle. These maturation processes are the subject of increasing interest as they could be involved in the regulation of gene expression and the response and adaptation adaptation to stress.