In addition to academia, industries are increasingly recognizing the value of investing in custom-built HTE setups to automate their synthesis workflows for enhancing the productivity. A fully integrated, cloud accessible, automated synthesis laboratory (ASL) was designed and built by Eli Lilly . This state-of-the-art facility comprises heating, cryogenic, microwave, and high-pressure reaction, evaporation, and work-up modules, empowering researchers to conduct an extensive array of chemical reactions. The ASL comprises of three bench spaces dedicated to either high temperature reaction, cryogenic/microwave reactions, or reaction workup. In each bench a translational combination of robotic arms perform the specific experiments using the modular platforms, while consumables and samples are transferred between benches through a conveyor belt linking them together. According to their article, the ASL has facilitated over 16,350 reactions at gram scale across various case studies, showcasing their widespread capability. Researchers at Samsung have pioneered the development of Synbot an innovative autonomous synthesis robot by leveraging artificial intelligence (AI) and robotic technology to establish optimal synthetic recipes . Similar to ASL, Synbot consists in five modules connected through a conveyor belt backbone with a robot arm in charge of transferring the samples between them. The modules include a pantry for chemical storage and selection, a dispensing module for solids and liquids, reaction module capable of heating and stirring, sample preparation module, and a liquid chromatography-mass spectrometer characterization module (Figure ). The efficiency of the system has been demonstrated through successful validations on three reactions namely, Suzuki-Miayura coupling, Buchwald-Hartwig amination, Ullmann coupling. These experiments showcased conversion rates that outperformed existing references and provided at least 6 times efficiency in the experimentation besides synthesis planning, optimization, and downstream workup tasks. The throughput of Synbot is estimated to be an average of 12 reactions within 24 hours depends on the reaction time. IBM RoboRXN has developed a remotely accessible autonomous chemical laboratory that enables 100 times acceleration in chemical synthesis by leveraging cloud computing, AI and automation. The details of this pioneering project can be found on their website.