In this contribution, we developed a novel molecular-to-mesoscale hybrid modeling approach by embedding solvated species treated by first-principle DFT in surrounding mesoscopic densities in solution described by cDFT. AIMD (DFT) provides high accuracy to the description of the atomic and electronic structure of solute including polarization interactions, while cDFT brings a detailed and accurate representation of the ion-ion and ion-solute interactions associated with the adjacent electrolyte.