Minerals are vital for health and well-being and are typically obtained from diet. Deficiencies in some minerals have been associated to age-related diseases. Thus, dysregulated calcium levels are correlated to accelerated cellular aging. Calcium-related changes upon aging are regarded as a contributing factor for neurological degenerative disorders such as Parkinson's disease. There is evidence that aging individuals are at risk of calcium deficit, so appropriate calcium dietary intake can lower the risk of osteoporosis and bone fractures. Zinc is another mineral that promotes healthy aging and supports healthspan. Zinc has numerous biological roles, such as antioxidant, antiinflammatory, immune modulation, DNA damage prevention, and others. Zinc insufficiency is often reported upon aging, and contributes to age-associated disorders. Thus, zinc supplementation is considered an efficient choice for controlling age-related health pathologies, including neurological disorders, infectious diseases, age-related macular degeneration. Long-chain polyunsaturated fatty acid supplementation is believed to protect human health by affecting biological activities, notably aging processes. Recent reports suggest that higher levels of ω3 fatty acids in circulation correlate with lower risk of premature death from age-associated diseases such as cardiovascular disease and cancer. 513 Dietary ω3 fatty acid consumption have been related to cognitive improvements in aging populations. The ω3 fatty acids have been shown to exhibit antiinflammatory, antiapoptotic, antioxidant, and endothelial vasodilator effects.