Our method for exploring reaction networks is based on the meta-molecular dynamics (meta-MD) approach proposed by Grimme. As we have demonstrated previously, an automated workflow that tracks the reactions occurring during the meta-MD simulations can be used as an efficient way of predicting which low-barrier (defined as <30 kcal/mol) reactions are possible. The combination of using a method that focuses on low-barrier reactions while relying on a fast semi-empirical quantum chemistry method (GFN2-xTB ) means that we can grow reaction networks quite fast even for larger molecular systems, making screening applications possible.