All data was collected utilizing an Agilent 1260 LC with MSD Agilent model 6120 single quadrupole mass spectrometer detector. The LC binary pump (model G1312B) attached to an autosampler (model G1329B), which uses an external tray for sample submission. The column compartment (model G1316C), is attached to a diode array (model G1315C). Agilent Easy Access (rev. A.06) is used for sample submission and ChemStation (rev. B.05.01) software is used for acquisition and data handling. General OA methods consist of either a 2-or 3-minute gradient of 5 -95 % B over 1.5 or 2.5 minutes respectively, with a 0.5 minute hold at this solvent concentration. Solvent A: Water (0.1% formic acid + 0.05% ammonium formate). Solvent B: Acetonitrile (5% H2O +0 .1% formic acid+ 0.05% ammonium formate). The flow rate is 1.0 mL/min using a Luna Omega Polar C18 column (2.1 x 30 mm, 1.6µm particle size) maintained at a temperature of 60 °C