1 H, 13 C, and 19 F NMR spectra were measured on a 600 MHz or 400 MHz NMR spectrometer using CDCl3, DMSO-d6 or D2O as the solvent with tetramethylsilane (TMS) as the internal standard. The 19 F NMR spectroscopy was used to determine the 19 F NMR data. Chemical shifts (δ) are given in parts per million relatives to TMS, and the coupling constants are given in hertz. The following abbreviations were used to explain the multiplicities: s = singlet, d = doublet, t = triplet, q = quartet, m = multiplet, brs = broad singlet. High-resolution mass spectrometry (HRMS) analysis was carried out using a TOF MS instrument with an APCI or ESI, EI source. Single-crystal X-ray diffraction studies were conducted at 293 K on the Bruker D8 VENTURE diffractometer equipped with a PHOTON-II detector (MoKα, λ = 0.71073 Å). An oil bath was used for heating when was needed. Column chromatography was performed using silica gel (300-400 mesh).