Critical fluence values were assessed by recording a time-series of SAED patterns at constant electron flux (fixed beam current) to track the decay of Bragg spot intensity with cumulative electron fluence. SAED Bragg diffraction spot decay measurements were taken on the pure phase alkane and pure phase alcohol samples and a 50:50 binary mixture of the two components in the "down-chain" orientation. Based on critical fluence values for paraffins with similar chain lengths reported in the literature, the electron beam flux was set up to support recording 20-30 data points containing observable diffraction intensities. All diffraction pattern series were acquired using the Titan microscope. An electron beam flux of 0.03 e -/Å 2 s at a fixed magnification was used giving a screen current of 0.076 nA. These values were calibrated using a Faraday cup. The cumulative electron fluence can be calculated by multiplying the time the sample has been exposed to the electron beam (in s) by the electron flux (J):