Kcal/mol compared to -12.25 Kcal/mol observed for lamellarin Z . Table contains all the calculated energy components which are also plotted for both compounds in We verified through the energy decomposition analysis that both compounds could interact strongly with ASP83, ASP75, ASP129, ASN152, and HIS51, as shown in Figure (C/D) . However, it was noticed that lamellarin Z (39) had much more unfavourable interactions with the other residues, especially TRP50 and SER81, with which lamellarin S showed no unfavourable interactions.