In summary, a super small Pd particle-loaded MOF was successfully fabricated by choosing Pd(PPh3)4 as the Pd precursor. The obtained Pd@MOF demonstrated dual-functional catalytic property for hydrogenation and HDO of biomass-derived carbonyl compound successfully during tuning reaction time. Additionally, our catalyst can also catalyze the reduction of nitrobenzene derivatives to the corresponding amines. We also prepared immersed-Pd/MOF and Pd-MOF by using different methods from the previous literature. By comparing the catalytic performance of Pd@MOF to both Pd-MOF and immersed-Pd/MOF, confirming the relationship between their reactivity and structure, the size and dispersibility of the Pd particles will directly affect the catalytic efficiency.