The mass of nucleic acid adsorbed per unit surface area (Γmax) was determined as the maximum value achieved at the end of the adsorption phase, for the highest concentration injected. The kinetic constants for the association of nucleic acid materials to polymer brushes were calculated based on a validated nucleic acid infiltration model . Briefly, the first 75 s of each adsorption kinetics were fit according to Eq. 1, in order to extract the corresponding apparent adsorption constant 𝑘 '(( , at each nucleic acid concentration. The linear relationship between kapp and the nucleic acid concentration (according to Eq. 2) was used to extract both the apparent absorption and desorption rate constants, 𝑘 '(( ! and 𝑘 '(( " , respectively. The affinity constant, 𝐾 ' measured as the ratio between these two constants,