Dissolution measurements. Each sample was prepared under identical mechanochemical conditions to ensure a reliable comparison of the dissolution rates among the samples. After synthesis, 0.20 mmol of the powder sample (<250 μm) was loaded into a scintillation vial (20 mL) with a stir bar. Then, 18 mL of deionized water, preheated to 37 °C, was added to the vial. The solution was stirred at 500 rpm while maintaining a temperature of 37 °C. Subsequently, 1 mL of the solution was drawn using a pipette and filtered with a syringe filter. Samples were collected at 0.5, 1.5, 3, 7, 15, and 30 minutes to ensure reaching equilibrium. The dissolution data in buffer (pH=6.8) at 0.5, 3, 7, and 30 minutes were also collected. Since the dissolution rate of the samples in the stomach is not as important as oral dissolution, solubility data in buffer (pH=1.2) was collected after 30 minutes. The concentration of the samples was determined by measuring their UV-Vis spectra. A linear calibration curve (R^2=0.9996) in water was established using the peak centered at 301 nm.