The SynTemp framework, introduced in this contribution, utilizes these principles for chemical reaction modeling. The purpose of SynTemp is to extract a limited number of reaction rules from a large collection of reaction data. In the following section, we describe in detail how this is achieved. Two key ingredients are (1) to consider a hierarchy of partial ITS graphs that contain the reaction centers as well as additional structural context of different size, and (2) to leverage clustering to extract reaction patterns that are consistently observed in a large collection of reaction data.