Among the mentioned and discussed methods for the preparation of Curcumin nanoparticles, the Nanoprecipitation, Co-precipitation and Wet Milling Method are considered as highly effective for Curcumin nanoparticles due to their ability to enhance solubility and bioavailability . Techniques like Freeze-Drying, Spray Drying and the Thin-Film Hydration offers stability, but may require careful optimization, hence are considered as mid-tier techniques . Coacervation, Desolvation and Emulsion Polymerization are less commonly used for Curcumin specifically due to limitation in yield, scalability or compatibility and are considered low tier methods .