Fig. presents an overview of the initial data set, which includes 4,521 compounds retrieved from ChEMBL 33. These compounds are associated with 32 distinct viral targets across 13 viruses implicated in respiratory infections. Among these, IAV is the most represented, with 1,968 compounds, followed by SARS-CoV-2, with 1,139 compounds. This distribution underscores a predominant research focus on these viruses, likely driven by their significant global impact, recurrent outbreaks, and the prioritization of pandemic-related research efforts. Indeed, the data set highlights a strong emphasis on highly studied targets such as proteases and polymerases, which play critical roles in viral replication and are central to current antiviral strategies.