To increase awareness among high school students about the role of metals in biology, we designed a series of four experiments/demonstrations focused on this topic. The impact of these experiments/demonstrations on enhancing knowledge among high school students was evaluated via "Metals in Biology" focused outreach sessions conducted in collaboration with Girls Inc. Eureka!, a five-year summer program at the University of Minnesota. The Eureka! outreach program focuses on female students from Minneapolis and St. Paul school districts entering high school (8 th and 9 th grade) and is aimed at supporting the professional interests of these students in STEM. All of the participants of the program are underrepresented minorities in STEM, including first-generation college applicants and students of color. Given that students are known to engage more proactively with personally-relevant content, our designed experiments focused on the ubiquity of metals in biological systems and their importance in organisms, especially humans. Each experiment was structured around a series of activelearning discussion questions to engage students and develop their critical thinking and comprehension skills. The primary goals of this outreach were: 1) educating students on the presence and importance of metals in biology, and 2) assessing if the incorporation of such content in the high school curriculum is feasible and beneficial. Our long-term goal with the outreach is to enhance students' interest in STEM fields and their ability to apply science not only in classrooms, but also in real-world scenarios.