Three different SILCS methods were applied to CB8 and achieved reasonable success; the top-performing method was a nonranked submission which included empirical weighting factors applied to the computed grid free energies in order to improve agreement with experimental results for CB8 in SAMPL6. This empirical tuning resulted in better performance here than for the other two SILCS-based methods (with an overall RMS error of 1.96 kcal/mol), though this submission (SILCS/LGFE/TIP3P/GCMC-MD/rew) was not ranked. This seems to further illustrate that empirical corrections to computed binding free energies can improve accuracy, at least in some cases.