Recent work has reported that additional conductance states may arise from in-backbone molecule-electrode linkages, in situ dimerization, or intermolecular interactions. To investigate the origin of the high G state, we synthesized the non-C2-symmetric terphenyl derivative R6-H containing only one terminal anchor using automated iterative cross-coupling (Fig. ). Single-molecule characterization using STM-BJ shows that R6-H cannot form stable molecular junctions and therefore does not exhibit a high G state (10 -3 G0) at 0.1 mM (Supplementary Fig. ). These results suggest that the high G state does not arise from intermolecular interactions or in-backbone linkages between the molecule and gold electrodes. To investigate the potential for solution-based aggregation, we performed an 1 H NMR dilution experiment at experimentally relevant concentrations for R6 (Supplementary Information, Section S.4; Supplementary Fig. ). Overall, these experiments showed no significant spectral changes for concentrations between 0.1 mM and 10 mM, which further suggests that solutionbased molecular aggregation is not responsible for the high G state.