the changes in the therthe Rabi splitting, their the VSC induced ħΩ R . VSC is not only an enery surface leading to the ange in reaction mechaevolution of ∆H ‡ and ∆S ‡ nteresting to see that the reaction, which could be formation and organisastep. er ∆H ‡ mostly represents irement for the formaindicates the degree of ambient conditions, the rough a pentacoordinate ciative mechanism with r value of ∆H ‡ (30 ± 4 kJ alue of T∆S ‡ (-54 ± 6 kJ y experiments agree well nd with a TS that is more reactant/intermediate-like as schematically displayed in Figure . Interestingly, the thermodynamic data show that the reaction proceeds through a more product-like TS as shown in Figure under VSC. The dissociative TS requires higher energy as it is more bond-breaking, and it is less strained because of the tetrahedral-like structure. This could mean that the intermediate generated under VSC is easier to form but more stable than the noncavity case either by a charge stabilisation or by anisotropic interactions induced by light-matter coupling. For example, mode selective chemistry experiments have shown that TS control of the reaction can be modulated by anisotropic forces either to enhance or suppress a particular reaction path [38]. In other words, the role of strong coupling could be more important in determining the position and structure of the TS as shown in recent experimental [6, 8] and theoretical studies [23, 24].