Recent experiments have demonstrated that coupling molecular vibrations to quantized radiation modes inside an optical cavity can lead to enhancement 112,119 or suppression of the rate constant for a reaction in the electronic ground state. Further, it has been shown that this vibrational strong coupling (VSC) regime can be leveraged to selectively break chemical bonds, 4 thus effectively realizing mode-selective chemistry. Interestingly, such modifications of chemical reactions operate "in the dark", 357 requiring no external source of photons (laser excitation), unlike the polariton photochemistry experiments summarized in Fig. . This new strategy in the VSC regime, if feasible, will allow one to bypass some intrinsic difficulties (such as intramolecular vibrational energy transfer) encountered in mode-selective chemistry that uses IR excitations to tune chemical reactivities, offering a paradigm-shift of synthetic chemistry through cavity-enabled bond-selective chemical transformations. On the other hand, recent experimental works have also reported possible discrepancies with negligible cavity modification to ground-state chemical kinetics. And theoretically, we do not have a satisfactory answer to explain these observed modified reactivities, despite recent progress. In the following section, we will provide a comprehensive overview of the existing experimental and theoretical works that have attempted to solve the mysteries of vibrational polariton chemistry.