In this report, we provide an overview of the current knowledge on antibiotic resistance, antibiotics, and antibacterial materials. Furthermore, we provide a landscape of the antibacterial field based on data from the CAS Content Collection , the largest human-curated collection of published scientific knowledge, which has proven useful for quantitative analysis of global scientific publications. Our analysis focuses on mining the CAS Content Collection for recent documents (2012 onwards) to uncover trends in journal and patent publications, the use of various substances, and for providing insights linking antibiotics with bacteria and disease indications. Additionally, we review the antibiotic resistance mechanisms, diverse classes of antibiotics, their modes of action, and emerging antibacterial strategies. The overarching aim of this report is to serve as a useful resource for understanding the current state of the field of antibacterials and global research efforts in this field.