In conclusion, we have reported an OC generated pulse sequence for efficient CP between spins with large anisotropic interactions. The experimental results are in full agreement with the simulations, showing a sensitivity improvement by a factor of ~50% using OPTIANS over the optimal ramped CP. We tested the robustness towards power level mismatch and change in MAS frequency both numerically and experimentally. The OPTIANS is significantly more forgiving to variations in these parameters. The method is offset selective on both the channels that can be used to selectively probe the local structures in different chemical environments. Since spins with large anisotropies are common in materials, the OPTIANS will find a vast set of applications from catalysts, battery to green energy and quantum material characterization.