Lamellarins are fascinating class of a broad family of marine polycyclic pyrrole derived alkaloids reported from numerous marine organisms including molluscs, ascidians, tunicates, and sponges. In 1985, Faulkner et al., reported the discovered the first four members lamellarins A-D from the prosobranch mollusk, Lamellaria sp., collected near Koror, Palau . Up to date, over 70 lamellarins and structurally related congeners have been reported, including other classes namely ningalins, lukianols, polycitones, and storniamides . Chemically, they are featuring of a common a polyaromatic ring system incooperating a central fused pyrrole scaffold, where positions 3 and 4 are decorated by polyhydroxy-or methoxyphenyl groups (aromatic A-, E-, and F-rings), and the 5,6-bond on ring D can be either saturated or unsaturated .