The raw streams are complex and diverse in composition, but usually are a mixture of one or more of the following feedstocks 5 : (i) biopolymers such as cellulose, hemicellulose, starch, chitin etc., (ii) mono or disaccharides such as glucose, sucrose, fructose, xylose, (iii) proteins, and (iv) extracts or secondary metabolites, such as triglycerides, terpenes, phenolics, tannins, carotenoids, sterols and flavonoids. Pretreatment technologies are required to fractionate the raw biowaste streams into these feedstocks, and further transformations can convert these feedstocks into value added platform chemicals for integration in chemical supply chains (details of this classification and specifics of the case study are given in Supporting Information, Figure ). Thus, there exists a complex network of options, when varied composition raw materials could be pretreated using different processing technologies and these would yield a variation of feedstocks streams. In the end, this mix of processing steps and technologies must remain economically and environmentally competitive. To enumerate the economic and the environmental performance and to identify most suitable target chemicals, a systematic evaluation of reaction pathway options is needed at an early stage of new process development. The evaluation is commonly based on a reaction network, 12 which may represent quite a significant part of chemical space. Different small-scale case studies have been conducted in literature, relying on networks originating from a feedstock or a platform chemical. For instance, the pathway evaluation for renewables by Bao et al. starts with cellulose (feedstock), Voll and Marquardt focus on itaconic acid (platform chemical) and Jacob et al. on limonene (feedstock). 14 However, these approaches do not yet account for the isolation of feedstocks from the biowaste streams in the first place, although for complete life cycle assessment of new technologies this is essential. Therefore, there is a need to expand reaction networks to include data on: (i) crude biowaste streams from which feedstocks can be obtained, and (ii) pretreatment methods to achieve this conversion.