Drinking water disinfection is critical to ensuring microbial drinking water quality and safeguarding public health . Disinfection is effective in killing pathogens, impeding microbiological recontamination, and inhibiting biofilm development in drinking water . Chlorine-based disinfectants, such as free chlorine (e.g., chlorine gas and sodium hypochlorite), bound or combined chlorine (e.g., monochloramine), and chlorine dioxide, are widely used in water treatment because of their cost-effectiveness and high efficiency . Nonetheless, when these disinfectants interact with natural organic matter (NOM) and anthropogenic compounds (such as pharmaceuticals and antimicrobials), they generate DBPs such as trihalomethanes (THMs), haloacetic acids (HAAs), haloketones (HKs), haloacetonitriles, halophenols, and halopropanoles . DBPs cause reproductive defects, carcer, and other serious health issues . Therefore, monitoring and controlling DBPs in drinking water is vital to public health . Conventional methods to monitor DBPs require expensive equipment such as gas chromatography (GC) and liquid chromatography (LC) combined with mass spectrometry (MS) and complicated pre-treatment processes. Thus, those conventional methods are labor-intensive, costly, and time-consuming, limiting the ability of water utilities to reduce DBP formation. By contrast, ML to monitor DBPs in drinking water are accurate, efficient, inexpensive, and easy to handle (Table ) .