Trypanosoma; the physicochemical properties or rules of Lipinski and Veber were obtained with the molinspiration platform . The parameters of toxicity on the genetic material of the cells, as well as the irritability that a compound can develop, were obtained with the DataWarrior software . In this first filtration of the chemical library, the molecules that met the following criteria were selected: probability of activit y ≥ 0.5 as an antiprotozoal on Trypanosoma, physicochemical properties that comply with the rules of Lipinski and Veber and parameters of zero toxicity.