The loss in weight of 7.5wt% gelatin hydrogels with different crosslinker concentrations in the presence of 0.1% trypsin solution is shown in Figure . The hydrogel with the highest concentration of genipin, i.e. 1wt% GP, showed little to no degradation, while the hydrogel without crosslinker was completely degraded between 8 and 24 h. Scanning electron microscope (SEM) confirmed degradation of the hydrogel with a higher pore formation after exposure to the enzyme (Figure ).