The temperature of the crystallisation cell was controlled by an external recirculating water bath that was connected to the inlet and outlet of the sample holder metal jacket. The pipes between water bath and crystallisation cell were insulated using foam pipe lagging, circulation of the coolant/ heating medium was performed using a pump (120s cased pump, Watson Marlow, Falmouth, UK), and the temperature was controlled by balancing variable heating with an in-built stirrer and PID controller (Anova Applied Electronics, San Francisco, CA, USA) against the near constant cooling from a surrounding ice bath. Using this setup it was possible to vary the temperature setpoint by 0.1 °C intervals and it was possible to ramp the temperature over the course of a measurement. Using water and ice as the respective circulating and cooling media, the temperature of the crystallisation cell up could be equilibrated between 4 °C to 90 °C without further adjustments. Crystallisation was triggered by slowly decreasing the temperature of the crystallisation cell.