While pharmaceutical manufacturing is moving towards more rational process design as part of Quality by Design (QbD) initiatives, pallet freezing process design is performed mostly in an empirical fashion and thus remains in the metaphorical dark ages. This is despite intense research related to freezing in the pharmaceutical context. In particular, these research activities established links between properties of the frozen product, like its mean ice crystal size or the extent of freeze concentration, and the freezing conditions. We posit that (part of) the reason why these valuable contributions have yet to reshape freezing process design in industry to a greater extent is because they are predominantly limited to the single-vial scale.