The use of the 16-port fluidic switching valve enabled us to screen 6 substrates molecules in one experimental run with no human intervention. We examined a substrate scope consisting of isopropanol, ethanol, acetaldehyde, trifluoroethanol, ethylene glycol, and glycerol (Scheme 1). We performed acid-base titration experiments using 1 M NaOH, performing pH measurements and CV after dispensing each 200 µL aliquot of NaOH. TEMPO and substrate were dispensed along with NaOH to keep the catalyst and substrate concentrations constant throughout the experiment at 2 mM and 100 mM, respectively. The solution was stirred by bubbling air when each aliquot of the mixture was dispensed, and the solution pH was measured after allowing the solution to settle.