Correlations between computed and experimental binding free energies for the base FF (Parsley) and BespokeFit (B3LYP-D3BJ/DZVP) are shown in Figure along with statistics and 95% confidence intervals as reported using cinnabar (formerly Arsenic) . Reassuringly the base FF, Parsley 1.3.0, performs very competitively achieving the sub 1 kcal/mol accuracy required to efficiently guide a drug discovery campaign.