The surface properties of hair fibers have been studied extensively using detailed all-atom MD simulations. Various experiments have explored the surface charge properties, lipid distribution, and changes from both chemical and physical damage. Despite its influence on key surface properties, modeling studies to date have neglected the protein component of the F-layer to which 18-MEA is attached. Our model not only explicitly treats the protein layer of the epicuticle, using KAP5-1 as the scaffold, but also allows for the study of surface response behavior to water and lipid adsorption. Given the agreement in 18-MEA layer properties, these models can be used to study complex interactions between cosmetic ingredients, polymers, and non-aqueous solvents. As the KAP5-1 layer is treated explicitly, penetration of molecules in hair care products can be explored to understand how they interact not only with an 18-MEA layer, including damaged surfaces, but also within the epicuticle layer. As we only modeled one segment of the KAP5-1 protein, it would be interesting to model the entire protein sequence along with inclusion KAP10-1 in a subsequent study to determine how well it is capable of creating attachable sites for 18-MEA and also explore different mixed protein structure models. We recognized the limitations of a homology model of truncated sequences, but the agreement between 18-MEA physical properties measured experimentally add confidence to the all-atom models described herein. Inclusion of different free fatty acid compositions and concentrations are also of interest, as it is known that the concentration of free fatty acids decreases from tip to root of the hair fiber . Using our all-atom model as a reference for constructing a coarse-grained model, future work can extend our studies to more complex surface interactions with solutions on longer time and length scales. The structurally accurate atomistic reference system developed in this work will be essential for reproducing the hydrophobic interactions which drive hair surface behavior.