2) Scale. Original syntheses of all compounds were performed on a milligram scale. However, after validation and optimization of the protocol, all amines 1g-11g, 13, and 15 were synthesized in 5 30 gram amounts in a single run (Scheme 1, Scheme 2). HCl-11g‧HCl. a Total as a white crystalline solid. All synthetic steps were optimized, and we could gram scale in a single by crystallographic analysis strategy, a library of CF 3 -diazirine containing isomeric/homologous pyrrolidines 2g-5g and synthesized from the corresponding commercially available alcohols (please, see SI for details). O-) was shown to work equally well as ) and we used both methods allowing and 10g were confirmed