A promising strategy for preventing infections in case of point-of-care devices and implantable medical devices are antimicrobial coating based on drug-releasing material (e.g. antibiotic/chlorhexidine/silver/ nitric oxide-releasing coatings) Such active coatings are able of killing microbes that approach the surface of the device, however applying them as an antifouling layer in cell cultures could influence the performed assays. Coating which does not release any molecules, but are based on repellent properties such a cationic biocidal polymers are more suitable for cell culture application. Photoactive coatings based on metal-oxide nanoparticles gained a lot of attention some time back . However the generation of reactive oxygen species (ROS) is highly detrimental for organic molecules, leading to protein dysfunction, membrane damage or oxidative stress, which is the core of the bactericide function could also negatively influence the cultured cells .