Chemical species transport and reaction mechanisms are central to the pathogenesis of various immune diseases. Dysregulated chemotaxis and haptotaxis contribute to excessive or insufficient leukocyte movement, leading to chronic inflammation or immune deficiency, respectively. Misregulation of cell adhesion molecules can result in inappropriate immune cell infiltration, contributing to autoimmune diseases and chronic inflammatory conditions . Bulk flow irregularities in the blood or lymphatic systems can alter distribution patterns of immune cells and signaling molecules, exacerbating conditions such as sepsis and rheumatoid arthritis . The disruption in chemical species transport and reactions plays pivotal roles in allergies; allergen exposure leads to macrophage and dendritic cell activation, triggering cytokine release and subsequent recruitment of eosinophils and T-helper 2 cells via chemotaxis . Similarly, in autoimmune diseases like multiple sclerosis, aberrant lymphocyte migration caused by dysregulated chemokine signaling can lead to tissue damage and chronic inflammation . These disruptions compromise the biophysical and biomechanical stability of tissues, exacerbating disease symptoms.