These results highlight the critical binding site residues that are found to be common Pro-A-248, and Tyr-A-264, shows weak to moderate interaction energy, that is why they falls in the Accessible-category residues. Unlike Lys-A-157, which was found to bind to one ligand (PDB-ID: 7SDR), with an unfavorable interaction energy. This is found due to the ligand's function group (hydroxyl on the para-position of the phenyl) that is forming a strong hydrogen bond with Glu-A-167. However, falling in the vicinity of the Lys-A-57