Interaction filters can be used to select ligands based on the presence or absence of specific interactions with the receptor, such as hydrogen bonds, van der Waals interactions, and reactive interactions. Any subset of receptor chain, residue name, residue number, and receptor atom name may be specified for the filter, e.g. "all results interacting with chain B" or "results establishing HB interactions with the backbone carbonyl oxygen of B:Thr276". Multiple interaction filters may be specified along with a missing interaction tolerance (max miss), which allows to specify how many interactions can be missed by a ligand while still being accepted. This functionality was explicitly designed to increase efficiency in the early stages of the analysis, when testing multiple interactions of unknown importance or presence in the dataset.