As an example, Fig. presents two different versions of the function ε(r) for several different solutes. These two versions are labeled "scheme 1" and "scheme 2" and correspond to different portions of each solute cavity being exposed to solvent (ε = ε solv ) or classified as hydrophobic (ε = ε nonp ). These two schemes are discussed in Section 4 .3. For now, it suffices to note, that the Voronoi-based permittivity functions that are plotted in Fig. can easily be mapped onto atomic choices for ε A in a HetPCM calculation.