They investigated the promotion of the radical scav-enging reaction of hydroquinone derivatives (Me n QH 2 , n=0-4) by aluminum ion, using 2,2-diphenyl-1-picrylhydrazyl (DPPH•) as a model for a peroxyl radical. The authors were able to determine the reduction/oxidation potentials of DPPH•/Me n QH 2 in the absence and presence of aluminum, concluding unequivocally that Al(III) enhances the electronaccepting ability of DPPH• and consequently accelerates the DPPH• scavenging reaction by hydroquinones. This supported previous studies where it was established that radical scavenging reactions can be affected by redox inactive metals, e.g., Mg(II), Al(III) and Sc(III). In the present work, we give computational support to this study, determining how the presence of aluminum can alter the oxidation/reduction potential of these species. To achieve our goal, we investigated the different coordination modes that aluminum can form with DPPH• and QH 2 mimicking the experimental conditions and assuming an outer-sphere mechanism, as done in the reference experimental study. Our results show a good agreement with experiments, and they allow us to identify the key species involved in promoting the redox reaction by aluminum. This gives valuable insights into the properties of aluminum that favor the electron transfer from hydroquinones to the 2,2-diphenyl-1-picrylhydrazyl radical, allowing us to identify unambiguously aluminum as a potential factor that alters the redox potentials of these species. Thus, our results provide a solid ground to identify Al 3+ as a possible toxic factor in biological media by affecting the thermodynamics of essential redox reactions, despite the non-redox nature of this metal.