Compounds in FooDB, encoded as SMILES strings , were standardized using the open-source cheminformatics toolkit RDKit 26 and Standardizer, LargestFragmentChoser, Uncharger, Reionizer y TautomerCanonicalizer functions implemented in MolVS 27 . Compounds with valence errors or any chemical element other than H, B, C, N, O, F, Si, P, S, Cl, Se, Br, and I were removed. Stereochemistry information, when available, was retained. Compounds with multiple components were split, and the largest component was retained. The remaining compounds were neutralized and reionized to generate the corresponding canonical tautomer.