In this work, we formalize an approach to general organic polymer simulations that simplifies parameterization of diverse macromolecule topologies and provide code to implement this approach. We begin with a description of the existing parameter-typed approach of the Open Force Field Initiative (OpenFF) as a solution to the inefficiency of atom-typed force fields for complex systems. Within the framework of the Open Force Field toolkit, we offer a SMIRKS-based specification for monomer templates that fill chemical information not present in legacy file formats using substructure queries. This is currently implemented in the OpenFF toolkit Topology.from pdb method of the openff-toolkit (located at , starting with release version 0.14.1 (August 1st, 2023). Finally, we present methods to assign atomic partial charges to large polymers, yielding fully specified system ready for valence and non-bonded parameterization with the Open Force Field Sage 2.0.0 force field.