and sodium acetate (64.5 mg, 0.79 mmol, 0.39 equiv.) were suspended in MeOH (8 mL), water (4 mL) and acetic acid (121 μL, 2.02 mmol, 1 equiv.). The solution mixture was stirred under reflux for 2 h. After complete consumption of 3 (by TLC), the reaction mixture was diluted in DCM (30 mL) and water (30 mL), then extracted with DCM (25 mL) four times and washed with 1 M NaHCO3 and brine. The combined organic layer was dried over anhydrous MgSO4, filtered and concentrated under reduced pressure. The residue was purified by CombiFlash (100% PE to 25% EA in PE).