LolEC. The Lipoprotein Outer membrane Localization EC protein complexes control traffic of bacterial lipoproteins. Deep-learning screening based on experimental inhibitory training-model developed from data on the Drug Repurposing Hub library , recently discovered Abaucin 67 . Abaucin, targeted LolEC, showed anti-A.baumannii activities at low µM ranges and suppressed mice infection. A. baumannii is a Gram-negative multi-drug resistant bacteria causing health care-associated infections world-wide with high mortality rates A. baumannii needs new drug discoveries possibly targeting the E protein as in E.coli . Higher affinities may help further improved Abaucinderivatives to reduce off-target physiological problems. Alphafold E.coli modeling of A. baumannii LolCE was employed to generate DW-BEL Abaucin-children in our previous work but Toxicity Risk was not available.