To improve the transferability of CG models, we defined the CG energy potential function contains the general bonded and non-bonded interactions, namely, 𝑉 𝐶𝐺 = 𝑉 𝑏𝑑 𝐶𝐺 + 𝑉 𝑛𝑏 𝐶𝐺 . Bonded interactions 𝑉 𝐵𝐷 𝐶𝐺 such as bond lengths, bond angles, and torsional interactions of the CG particles were inherited from the corresponding parameters of the GAFF1 force fields. For CG models of low resolution, bonded interactions were derived using direct Boltzmann inversion method, where the correlation functions were