After identifying the optimal catalyst, the catalytic Claisen rearrangement with 3j was screened with variety of allyl alcohol classes (see Figure ). The reactions between the allyl alcohols 1a-j and 2methoxypropene 2d in 1,2-dichlorobenzene (o-DCB) were run at 120 C under thermal conditions without pressure (reflux, open flask). The yields with class 1 alcohols with R 3 substituents varied between 40 % to quantitative (Scheme 4). Interestingly, alcohols with phenyl and p-methoxyphenyl groups as R 3 substituents led to low yields (6f, 6g) but a p-trifluoromethylphenyl group was well tolerated (6h). Both Boc-protected amines (6d) and allylic benzyl ethers (6i) survived the reaction conditions. To our delight, Claisen rearrangements with 3j as the catalyst in a sealed microwave tube at 120 C led to excellent conversions with all alcohol classes (Scheme 5). The low yield with 6f under thermal (open flask conditions, see Scheme 4) was improved to 98% in 1 mmol scale in the microwave conditions (Scheme 5). The stability of four different protecting groups were explored, and silyl-or benzyl-protected alcohols (6q, 6s, 6u, 6y, 6aa) and Boc-protected amines (6z, see also 6d in Scheme 4) survived the conditions, although the silyl-and benzyl-protected alcohols generally gave better yields. Limitations of the method include highly hindered tertiary alcohols 1n and 1o (class 1b) as their exposure to the reaction conditions resulted in the recovery of the starting materials.