For brevity, we do not provide the matrix and vector entries of M and Ψ for each method here, and refer to the supporting information for a brief overview. For a detailed derivation and discussion on this topic, we refer to [61, Section 2], [64, Section III], and [67, Section 6.2.2] for the ddCOSMO, ddPCM, and the ddLPB method, respectively.