With the second method, the temperature dependence of ∆H diss,T is accounted for through numerical integration and the solid solubility can be calculated for a broader temperature range, but a limited amount of solvents. To calculate the solid solubility at temperature T with the second method, the expression for ∆H diss,T given in Eq. 7 is plugged into the integral in Eq. 5. After integration, this yields Eq. 11. ∆H sub,298K is defined as the enthalpy of sublimation at 298K and is independent of temperature.