The polymer workflow for SMIRNOFF force fields was tested on various systems ranging from small polymers of < 10 2 atoms to large macromolecules on the order of 10 5 atoms to stresstest the workflow. Here, we tested only the ability of the modified toolkit to parameterize each system and did not attempt to simulate or predict properties, as is done later for PEG, PAAm, and PNIPAAm. For each system, summarized in Table , a PDB file with CONECT records was first loaded and assigned chemical information using templates following the format specified above. Gasteiger charges were used for the initial loading tests, as they were sufficiently accurate to demonstrate successful loading and parameterization (see the next section for the demonstration of RCT and GNN charging). With each system completely specified, parameterization was performed with the Open Force Field toolkit, followed by energy minimization with OpenMM. During parameterization, the OpenFF toolkit molecule caching ability for identical molecules was turned off for all time testing to simulate the worst-case runtime of a system of non-identical polymer chains and deconvolute the effects of the default parameterization procedure with the caching performance of the toolkit.