In each of the synthetic reactions in Fig. , the reagents were placed on the top of the organolithium gel which had been formed within a vial. The obtained results demonstrate that under this experimental set-up, the organolithium reagents within the gel are highly stabilised. However, for general and practical use, we next prepared gel 'blocks' loaded with a specified amount of organolithium reagent that could be directly and easily transferred under ambient conditions to another reaction vessel (such as a round-bottomed flask) containing the other reagents. To achieve this, the original organolithium gel formation procedure was modified enabling us to prepare the gel inside a plastic syringe (Fig. for PhLigel). In particular, it was necessary to modify the concentration of gelator and organolithium reagent within the gel in order to produce an organolithium gel block that was stable after exposure to air (see ESI). Ultimately, increasing the concentration of the C36H74 gelator from 2.8% wt/vol to 16.7% wt/vol and diluting the commercial PhLi solution to 0.6 M concentration in dibutyl ether resulted in the formation of a PhLigel block that was mechanically stable under ambient conditions and could be easily transferred using gloves. Based on titration experiments, it was evident that decomposition of the organolithium reagent during gel preparation was negligible (see ESI). It was also possible to incorporate BuLi into a gel block using a similar procedure and concentration of the reagents (15.6% wt/vol C36H74 gelator) (see ESI). With a successful method for the preparation of a PhLigel block in place, the stability and reactivity with 2′-methoxyacetophenone 1 under a variety of storage conditions were explored (Fig. ). After preparing the PhLigel block (2 equiv.) and storing for 30 s under ambient conditions in air, it was added to the 2′-methoxyacetophenone 1 in solvent. Upon stirring, the gel block broke down to release the PhLi into the solution and a 96% conversion to 2 was obtained (Entry 1). Storing for 30 min before reaction led to a lower conversion to 2 (78%) (Entry 2). The PhLigel blocks were more sensitive to storage than the gels in vials, presumably due to their greater surface area, with surface-located PhLi being more able to react with moisture in the ambient air. However, a 2 h storage time in air in a closed vial restored a high conversion to 2 (98%) (Entry 3) which was essentially maintained over 7 days under nitrogen in a closed vial (Entries 4 and 5). Alternatively, storage of the PhLigel block in an inert atmosphere, by leaving it in the syringe with the needle blocked in a rubber stopper, was an effective way of maintaining the activity. A similar profile of stability was also observed with the BuLigel block (see ESI).