When introducing his work on the First General Index of Molecular Complexity in 1980, Bertz stated that "synthetic chemists have been defining a 'complex molecule' in the way that many people define art: they know it when they see it." While this quote refers to molecular complexity, it encapsulates the lack of systematic approaches for predicting the related concept of molecular synthesizability. Synthesizability is governed by many factors, including synthetic routes, experimental conditions, precursor availability, and decomposition pathways. Amidst these factors, there is no universally-accepted definition of synthesizability or approach to calculating and evaluating it. While manually-predicted synthesizability based on expert intuition has long been the de-facto ground truth by chemists, it takes many people to only screen a few thousand molecules at a time. With billions of enumerable molecules in existence, faster computer-aided methods for predicting synthesizability are invaluable.