In order to demonstrate how Golem is integrated into Atlas, we reproduce the setup of the noisy high-performance liquid chromatography (HPLC) protocol optimization experiment from the original publication. In this application, an HPLC protocol is calibrated by adjusting 6 process parameters with the goal of maximizing the amount of drawn sample reaching the detector (referred to as the peak area). It is assumed that input parameters P1 (sample loop) and P3 (tubing volume) are subject to significant noise, and that the other four parameters are noiseless. Normally distributed noise truncated at zero is used for both parameters, with standard deviations of 0.008 mL and 0.08 mL for P1 and P3, respectively. The HPLC response is emulated within the Olympus package using BNNs (hplc dataset).