The integrated plant and microbial oil processing pathway developed in this study (available as installable open-source applications in Python) could be modified to produce a wide range of oleochemicals (e.g., thermoset plastics through ozonolysis and plasticizers through epoxidation) and biofuels (e.g., green diesel and sustainable aviation fuel) with lower environmental impact and land usage than soybean oil-based pathways. Biomass-based pathways are critical for achieving the Sustainable Aviation Fuel (SAF) Grand Challenge to supply 3 billion gallons of SAF per year by 2030 and replace 100% of conventional jet fuel by 2050. However, the use of feedstocks such as corn (through the alcohol-to-jet pathway) and soybean (through hydroprocessed esters and fatty acids) for SAF production is linked with high land use expansion that limits our ability to scale. The configurations for plant and microbial oil processing developed in this study may provide an avenue for even greener and more scalable biomass-based SAF. Further techno-economic and life cycle assessment studies are needed to quantify the potential benefits of plant/microbial oil pathways to oil-based biofuels and oleochemicals other than biodiesel.