DT's release study from the micelle was conducted by using a dissolution procedure that has been previously discussed somewhere else with mild modification . In short, the pH of the micellized DT solution was reduced to 1.5 (resembling gastric pH) through addition of 0.1M HCl (dissolution medium) in a covered amber glass beaker. The temperature was maintained at 37 ± 0.5 °C, mimicking the body temperature. The amount of liberated DT in the system was determined by sampling at regular intervals. After comparing with different models, the Korsmeyer-Peppas model was found better suitable to explain the release profile . Equation 4 states the model. dependent on the micelle's shape. The 'α' value for a spherical structure system normally varies between 0.43 and 0.85" .