Therefore, the main reaction templates in CARE describe X-Y (X,Y =C, H, O) bond-breaking reactions, and adsorption/desorption of closed-shell and other key molecules. Additional reaction templates account for intramolec-ular rearrangements such as 1,2-hydrogen shift, and a specific template for proton-coupled electron transfer (PCET) steps enabling modeling reaction networks under electrochemical conditions. The modularity of the network generator allows the inclusion of more reaction classes if required, for instance reactivity in solution at the interfaces of electrodes.