Several factors contribute to this feature of PGM catalysts. Because noble metals exhibit relative inertness, they possess distinct resistance to corrosion and oxidation under various conditions, such as the different intermediates within ORR, including acidic, alkaline, and aprotic solutions. Such resistance is linked to their electronic structure and the arrangement of the outermost electrons. Further, noble metal catalysts also have a stronger metal-support interaction (MSI) with their supported material. A stronger MSI means more stabilized metal nanoparticles on the supported material; this prevents the occurrence of agglomeration of the metal particles, leaving a high dispersion of active sites . These all contribute to minimizing the process of Ostwald ripening within the fuel cells, which was one of the main factors that impacted the durability of a catalyst mentioned in the last section.