We additionally examined the contributions from the fitted gas phase parameters (𝐴, 𝐸 𝑎 ) and solvation parameters (ΔΔ𝐺 ‡ solv (298 K), ΔΔ𝐻 ‡ solv (298 K)) separately for our method. The results are provided for six representative reactions in Figure . The liquid phase rate constants estimated using all four parameters are presented in blue solid lines (𝑘 liq, fitted ), and the "gas phase" rate constants estimated using only 𝐴 and 𝐸 𝑎 are presented in dotted red lines (𝑘 gas, fitted ).