A major hurdle for microfluidic MFCs is to improve their operational times. For example, one study using the same 6 mm electrode separation membraneless MFCs shown here achieve 6month operational time, but in another study using the same design, we had to solve a problem of a developing power overshoot. Each new design modification should be evalued from the perspective of operational longevity. With this goal in mind, we next verify the effect of the acetate oxidation products (Eqn. 8) on their interaction with the membrane because the membrane can be dissolved in solutions with pH lower than 5. To accomplish this, we simulated the proton concentration profile in the vicinity of the membrane (Figures and).