Derivatives 13-14 were each synthesized in straightforward two step procedures from 5 and 10 as summarized in Scheme 1. The diamines 5 and 10 on treatment with -bromo acetyl chloride to give the bromo derivatives 11 and 12 in 69% and 66% yields, respectively. The bromo derivatives 11 under treatment with 2-pyridyl methanol gives the pyridyl derivative 13 as an oil in 59% yield after chromatographic purification. Attempts to prepare 14 by reaction of 12 with 2-pyridyl methanol in the presence of triethylamine or NaH were unsuccessful and resulted in the isolation of pyridyl ester product with elimination of aromatic moiety (by nmr), it is understood that due to the steric hindrance, elimination of aromatic moiety might occur. (Scheme 3). Reaction of 5 and 10 with 2.2 eq of 1,3-dithiolane-2-carbonyl chloride in the presence of triethylamine in THF led to the isolation of the bis(1,3-dithiolanyl) products 15 and 16 as white solids in 55% and 73% yield after purifications using column chromatography. The 16 structure is also confirmed by single crystal data. (Scheme 4). In a similar procedure, compound 5 was reacted with 2.2 equivalents of -benzyloximino acid chloride . After chromatographic separation, 2,6-bis-benzyloxy methylester 19 was isolated in 66% yield along with the 6-mono-benzyloxy methylester 20 in 5% yields. Both compounds were isolated as white solids. (Scheme 6). We also attempted to synthesize the 2,3-bis-benzyloxy methyl ester 22 from direct nucleophilic substitution reactions of diamine 10 with -benzyloximino acid chloride in either of TEA or pyridine and sodium hydride method. In both cases, our attempts were unsuccessful and resulted in either the isolation of starting materials or unidentified mixtures of products. But we were successful in synthesizing the 22 in two steps via acetonide protection (Scheme 7). Thus, reaction of 10 with 2,2-dimethoxy propane in presence catalytic amount of para toluene sulfonic acid gave 21 as residual oil in 47% yield after column chromatography purification, and reaction with -benzyloximino acid chloride and workup with dil HCl gave 22 as white solid in 78% yield after chromatographic purification (Scheme 7). It is worth to mentioned that the while doing the Curtius rearrangement on compound 3, on heating at 110 o C gives urea derivatives, which is common intermediate step for the synthesis of quinazoline derivatives which having biological properties . Under acidic condition 24 gives benzo[d] [1,3]oxazin-4-one and in basic condition gives 2,4-quinazolindione derivatives respectively (scheme-9).