We apply FMOPhore scanning on the apo-structure of the binding site for both protein kinases. (Figure .). The FP-score was used to classify and categorize the binding site residues. By superposing both binding sites, (Figure . A. B and C), it shows that on the JAK-2 binding site the Lys-A-857, Val-A-863, Lys-A-882, Val-A-911, and Met-A-929 that superpose to the same position as the corresponding residues on the PKB share the same category.