For Lig-02 (7JRN), although C-01 shows the longest residence time (t) of 118 ns out of the 600 ns trajectories) (Figure ), P-score prioritizes C-04 as the pose of interest which shows much lower residence time (t) of 55 ns. Also, P-score can identify that C-02 for Lig-03 (7RZC) and C-04 for Lig-02 (7JRN) yet it also says that both predicted poses are on the border line of residence time (normalization of residence time (Figure ), which means, these poses can be significant but prolongation of SuMD simulations is recommended to increase the percentage of confidence in selected poses.