Similarly, we were able to demonstrate the compatibility of the method with a reasonably complex natural product derivative featuring multiple stereogenic centres by attaching an allylic phosphate to the female sex hormone estrone. This example also features a bis-allylic alcohol where diethyl phosphate leaves preferentially to a phenol-based group. Complete chemo-and regioselectivity was observed in the formation of white solid 61 (93% yield), with almost identical results on a 3 mmol scale at half the catalyst loading to give 1.31 g (97%) of 61.