1. Sourcing a training set of molecules and selecting particular measurements for each molecule (or pair of molecules) of interest. 2. Optimizing only the selected LJ parameters against the training set using ForceBalance in combination with the OpenFF Evaluator framework , starting from the OpenFF 1.0.0 (Parsley) force field parameters. 3. Assessing the performance of the trained force field against a test set of measurements using the OpenFF Evaluator framework. The goal of the study was to assess whether training the LJ parameters against properties of mixtures, as well as combinations of pure/mixture properties, is more beneficial than training against properties of pure systems. Other force field parameters, namely the valence and electrostatic parameters, were not optimized.