In summary, we have demonstrated the modification of mesoporous indium tin oxide electrodes with macrocyclic pillar [6]arene and subsequent binding of three ruthenium complexes via host-guest interactions for further utilisation in electrocatalysis. These host-guest-modified electrodes were employed for alcohol oxidation (pH 2.4) as well as ammonia oxidation (pH 10.8), highlighting reasonable stability in both acidic and alkaline media. The catalysts were reabsorbed to undertake a second round of catalysis, indicating prolonged stability of the surface-bound PA [6]. pH-dependent experiments revealed that alcohol oxidation remains feasible down to pH 1, despite observing partial desorption of the host. Ammonia oxidation remains viable above pH 11, however, reabsorption is hindered due to the low stability of surface-bound PA [6] within this pH range. Further functionalisation of the host, PA [6], could enhance the system stability and enable electrocatalysis beyond the observed pH range for unfunctionalised PA [6]. Beyond the reabsorption and repetitive electrocatalysis under identical conditions, we have further shown that PA [6]-modified electrodes can be used for subsequent reactions in different media. This was evidenced by performing alcohol oxidation followed by ammonia oxidation (and vice versa) on the same sample, achieved simply by reabsorbing the same or a different catalyst. This represents a first step towards the production of pH-stable host-guest-modified electrodes for electrocatalysis.