It was therefore of great interest for us to evaluate which of those novel methods could replace our approach using the rule based OSRA. The mentioned recent publications on those AI methods provide performance data, comparing precision and recall. For example, in Qian et al. besides Img2Mol, SwinOCSR, OSRA, and MolVec also MSE-DUDL, ChemGrapher, Image2Graph are compared to MolScribe's structure prediction quality, but showing considerably lower performance. In the present work, we are comparing our current tool OSRA with MolScribe, RxnScribe, DECIMER, ReactionDataExtractor, SwinOCSR, and the most recently published OCMR which became available after our ChemRxiv preprint . MSE-DUDL, ChemGrapher, Image2Graph are not available publicly which was a requirement for our evaluation. Img2Mol was not evaluated as it does not predict stereochemistry and was extensively characterised in as being considerably inferior to MolScribe.