cells with IC50 values of 8.4, 9.6, 10.7, 11.6, and 16.1 μM, respectively, whereas alterporriol Z3 (128) did not display any anti-inflammatory activity . On the other hand, another previous study demonstrated the potent cytotoxicity of alterporriol F (124) against the HeLa and KB human cell lines with IC50 values of 6.5 and 7.0 μg/mL, respectively . In addition, did not demonstrate any bioactivity when it was evaluated for its cytotoxicity, antibacterial activity, and antiviral activities .