SARS -Cov2 has immerged as one of the deadly viruses of the 21 st century and starting late 2019 and beginning of 2020 , COVID-19 has been declared a pandemic effecting not only health of the existing population but also causing economic disasters in several places around the world . SARS -Cov2 is a positive strand RNA virus and replication of its genetic material is crucial to its survival and spread among human host . RNA dependent RNA polymerase is utilized by SARS-COV2 to propagate and spread among human population and is one of the drug targets in treating COVID-19 .