The metabolic pathways involving alanine, aspartate, and glutamate, three important amino acids, have been implicated in the development and progression of FMC. Understanding the role of these amino acids in cancer metabolism may shed light on the underlying mechanisms of this cancer. Alanine, aspartate, and glutamate are interrelated amino acids that are involved in various cellular processes, including protein synthesis, energy production, and redox balance. The metabolism of these amino acids is tightly regulated by a group of enzymes known as aminotransferases, which facilitates the transfer of amino groups between these amino acids. Dysregulation of these enzymes and altered expression of genes involved in the metabolism of these amino acids have been observed in cancer, including FMC in cats. One of the key roles of alanine metabolism in cancer is its involvement in cellular energy production.