Haptic feedback is the sensorial mechanism used to simulate a sense of touch and is used to convey the application of motion or forces, the difference between the weight of virtual objects, or the textural feeling of geometry or surface. HTC Vive's hand controller (Figure ) has a built-in haptic feedback mechanism which vibrates to simulate a sense of weight and friction. MINT exploits this feature to make the overall user interface responsive and lively. The variation of vibration depends on both its duration and its strength and adjusting these two factors opens different dialogs with user: For example, clicking a button on the menu interface generates short and mild vibration that imitates the sense of pressing a mechanical button, while clashing a protein and a ligand by dragging them together produces long and strong vibration to indicates the physical collision of such a clash. Similarly, rotating angular bonds between atoms returns a consecutive and blunt vibration in short intervals on to resembles the sense of turning a crank.