In the vast landscape of medical conditions, rare diseases occupy a unique and often overlooked niche. Defined by their low prevalence, these disorders collectively affect millions worldwide , presenting a multitude of challenges to patients, healthcare professionals, and researchers. Moreover, rare diseases offer a window into the diversity of human health and the complexity of biological systems. Each condition represents a unique manifestation of genetic, environmental, or infectious factors, often with distinct clinical presentations and treatment challenges. From rare genetic disorders like cystic fibrosis and Huntington's disease to autoimmune conditions like lupus, myasthenia gravis, and rare cancers, the spectrum of rare diseases encompasses a broad array of pathologies.