Next, the developed protocol was successfully scaled-up, accessing up to 76.2 g of compound 4b in a single run with no significant decrease in the reaction yield (78% vs 81%). This product was subjected to some standard chemical transformations illustrating its synthetic potential (Scheme 4). Thus, treatment of ester 4b with NH3 solution in dioxane cleanly formed amide 6 in 86% yield. Alkaline hydrolysis of compound 4b block produced potassium salt of carboxylic acid 7 in 85% yield (corresponding acid was found to be unstable in free form). Treatment of compound 4b with m-CPBA produced corresponding epoxide 8 (79% yield). Reduction of the same starting material with H2 over Pd catalyst or using NaBH4 gave corresponding products 9 and 10 in 76% and 77% yield, respectively. At the same time, it should be noted that reaction of 4b with CH2N2 or [3+2] cycloaddition with in situ generated azomethine ylide 55, under various reported conditions were unsuccessful, leaving the starting alkene intact.