Experimentally, the best solubilizer was found to be A-pBuOzi-A (solubility of DSA ≈ 2.8 g/L at 4 g/L DSA feed) (LC ≈ 22 wt.% and LE ≈ 70%), diametrially opposite to the prediction. The aqueous solubility of DSA was found to be 0.003 g/L (Table ), meaning a 930-fold increase of the apparent solubility could be achieved. For A-pBuOx-A, increase in DSA feed did not improve the solubility (remained ≈ 2 g/L at all DSA feeds), on the contrary, a weak trend was observed with respect to decrease in solubility of DSA for A-pPentOx-A and A-pBuOzi-A with the increasing DSA feed (Figure ). The A-pPrOzi-A was found to be the least efficient solubilizer for DSA (solubility ≈ 0.2 g/L at 4 g/L DSA feed) (LC ≈ 2 wt.% and LE ≈ 5%). According to Li et al., PEG-PCL micelles were capable to solubilize only 0.19 g/L of DSA . A strong polymer-drug specificity is apparent for A-pBuOzi-A and A-pPrOzi-A, although both differ from each other by just one methylene unit in the side chain of the hydrophobic block. Again, the obtained formulation results were not in line with compatibility trend expected from Ra calculation.