showed that both 2n-6k and 2o-6k effectively reduced the LPS-mediated cytotoxicity in a concentration-dependent manner. Interestingly, the cytoprotective activity of 100 μg/mL of both polymers was comparable to those of the equivalent amount of ibuprofen (4.3 μg/mL) and glycyrretinic acid (12.7 μg/mL), indicating that the drugs were released from PEO in cells to exert their therapeutic actions.