Diffusion plays an indispensable role in cellular homeostasis and reproductive function. The movement of ions and small molecules across biological membranes through diffusion is influenced by concentration gradients and is essential for cellular communication, oxygen, nutrient delivery, and hormone signaling within the reproductive system . Alterations in the diffusion of critical hormones like estrogen can lead to dysregulation in ovarian function, as seen in polycystic ovary syndrome (PCOS) . It is also pivotal in the pathology of diseases like endometriosis, where altered diffusion rates of inflammatory cytokines can exacerbate the inflammatory response . The interplay between local chemical microenvironments and spatially restricted diffusion rates is vital for understanding reproductive pathologies.