Hence, the flexibility and practicality of the probe were greatly improved. Figure shows its advantages and extreme softness. Moreover, the fabrication process was much easier, less time consuming, and the cost of the novel soft gold ultramicroelectrode was low. In previous literature, we demonstrate the capability of soft carbon stylus microelectrode for scanning various fragile and rugged samples, for instance, melanoma tissues, without damaging the tip or the sample. Therefore, we used the novel soft gold ultramicroelectrode developed in this work for further human tissue scanning experiments.