Looking at literature outside the timeframe of the dataset, we found that the DMT/DBT donors have received considerable attention in enzymatic glycosylations , but much less attention in chemical glycosylations. We were only able to find one report of chemical glycosylation with a similar donor preceding the introduction of the DMT-donor by Fujimoto in 2013. In 1998 Schmidt investigated multiple hetaryl glycosides as donors in catalytic glycosylations , including a perbenzylated 2,4-dichlorotriazine glucoside. Only the α-product is observed for glycosylations with this donor, whereas the corresponding TCA donor gives a 3:2 (α/β) mixture of anomers under the same conditions. We were also only able to find one study investigating these donors in the period after 2015, which is a recent follow-up study on the hydrogenolysis methodology by Shoda. For all glycosylations in Figure , the donor is the β-anomer, thus, the observed α-selectivity might be due to stereospecificity. We envision that the DMT/DBT-donors can be a valuable alternative to the TCA-donors is cases where α-selectivty is difficult to obtain with TCA-donors. The second interesting trend inferred from the full tree is that if the glycosyl donor is a 2-deoxy sugar and the solvent is acetonitrile, the major glycoside product will be the α-anomer. This is the opposite of what is usually expected according to the nitrile effect. It is well-known that the increased reactivity of 2-deoxy donors gives rise to great differences in stereoselectivity compared to their 2-substituted counterparts, and the solvent effects for 2-deoxy glycosyl donors are not well understood. The reactions ending up in this leaf are quite different in conditions and substrate scope, and examples can be seen in Figure . The first set of reactions comes from an investigation of the effect of acceptor nucleophilicity on the stereoselectivity by Beaver and Woerpel from 2010. They observe high α-selectivity for reactions between 2-deoxy glycosyl acetate and carbon nucleophiles and reactions between 2-deoxy thioglycosyl donors and weak oxygen nucleophiles (Figure ). However, when changing the solvent from MeCN to DCM a drop in selectivity is observed which they ascribe to an increased stabilization of the glycosyl cation in acetonitrile leading to a stereoelectronically controlled attack rather than an attack at a rate near the diffusion limit. Shimoyama et al. were interested in performing α-selective glycosylations using the 2-keto-3-deoxy N-trifluoroacetimidate in Figure as the glycosyl donor. After a solvent screening, they end up with a highly selective procedure with acetonitrile as the solvent. They attribute the high stereoselectivity to the isopropylidene at the 4,5-O-position. However, during the solvent screening, they also observed high αselectivity for both DCM, toluene, and ether solvents while acetone and ethyl acetate gives a 1:1 mixture of anomers. Thus, the solvent also affects the stereoselectivity and this effect does not seem to be correlated with the polarity of the solvent. Nakanishi et al. developed an α-selective light-induced O-glycosylation procedure with unprotected deoxythioglycosyl donors. The reactions give high α-selectivity in acetonitrile, though no other solvents are tested, making it difficult to assess the influence of the solvent on the stereoselectivity. Albeit all the reactions in Figure are highly α-selective despite being very different methodologies except being carried out in acetonitrile, thus it seems possible that an "inverse-nitrile effect" is present for some glycosylations with 2-deoxy donors, which can also be utilized for other methodologies.