The most recent survey of BindingDB users, which occurred in 2020, indicated that about 80% work in academia, with the rest spread across government, industry, and other/no affiliation. When allowed to select multiple application areas, 75% said they use BindingDB for drug discovery, 30% for chemical biology, 25% for development of physics-based models, 15% for machine learning/artificial intelligence training and testing, 15% for systems biology, and 10% for toxicology. Again allowing multiple responses, 75% said they browse/query the website, 45% download data, 15% integrate the downloaded data with a local database, and 10% use BindingDB webservices.