To more formally demonstrate why this terminology is problematic, in Box 2 we examine the equations that describe the rotation of catenane motor 6 and the work it can perform. These equations have the same features as all information motors operating at non-equilibrium steady state, allowing us to reach general conclusions that contradict the macroscopic preconceptions the word "fuel" conjures: i. The motor can turn in either direction, regardless of the value of ∆G rxn , including if ∆G rxn = 0, depending on the concentrations of the species in the coupled process.