Recently, in 2019, Eurtivong et al., investigated virtually through a molecule docking approach the antiviral profiling of 8 lamellarins type I compounds as promising HIV-1 integrase strand transfer complex. The authors highlighted that such oxygenated polyaromatic pyrrolic compounds are interacting effectively via hydrogen bonding with a key residue Glu92 beside other potential residues including Cys65, His67, Asp64 and Asp116 .