Jiang's group described a powerful sensitive nonenzymatic glucose sensor based on CuO NPs modified carbon nanotubes (MWCNTs) catalyst. Many physicochemical methods were employed to evaluate the performance of the developed anode material.So, at +0.4 V applied potential, the (CuO NPs/MWCNTs) shows higher sensitivity as high as 2596 µA.mM -1 .cm -2 to glucose. Also, a linear range hold over a concentration up to 1.2 mM with a detection limit as low as 0.2 µM (signal/noise = 3). Particularly, the sensor was highly resistant against the poisoning ion chloride, the impact of the oxidation of common interfering species. As supposed, the (CuO NPs/MWCNTs) sensor was far beyond to the unmodified MWCNTs. Indeed, justifying the role played by each component of the hybrid catalyst. Therefore, it summarized that this kind of sensor is bright for the future elaboration of nonenzymatic glucose sensors. Furthermore, in 2012, Luo's research team proposed a sensor based copper nanoparticles (Cu NPs) modified graphene sheets (GSs) as a nonenzymatic glucose sensor. Indeed, it is thought that due to the synergistic effect between Cu NPs and GSs, a high oxidation current and as well as a negative shift in the peak potential were achieved. So, at 0.5 V, the Cu NPs/GSs exhibited a wide linear range up to 4.5 mM glucose with a LOD of 0.5 µM. Due to the synergistic effects, the Cu NPs/GSs delivers high stability, selectivity, sensibility, and as well as fast amperometric detection of glucose, which suggest that Cu NPs/GSs might be useful for the development of nonenzymatic glucose sensors. More recently, a modified electrode is reported from Yuan's group as a nonenzymatic glucose sensor and beyond. The (NiO NPs/GO/GC) catalyst was characterized by many technics including physical and electrochemical methods. So, when compared to (NiO NPs/GC) electrode, the proposed (NiO NPs/GO/GC) catalyst showed poor resistivity, powerful capacitive properties behavior (16-folds) and as well as better glucose oxidation reaction. The glucose linear range was from 3.13 µM to 3.05 mM with a detection limit of 1.0 µM. Also, common interfering substances were no longer have a meaningful impact on the detection of glucose. Therefore, as described here, there are many materials in diverse forms nowadays which are available in the mark for both glucose oxidation and detection. But, always it still some issues to master this concern such the materials costs, the process optimization and cost, the environmental friendliness of the suggested catalysts, and so on. In the next section, it will be focused on the catalytic oxidation or detection of dopamine levels in the human serum and urine.