Malaria is an infectious and life-threatening disease that affects nearly half the population of the world, it is typically found in tropical and subtropical climates where the parasite can grow. Africa is responsible for 90% of worldwide malaria morbidity and death, particularly pediatric mortality vulnerability. Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and Plasmodium knowlesi are the most common plasmodium parasites that cause malaria . Plasmodium falciparum is the most dangerous human malaria parasite, and it is responsible for the majority of malaria infections in Sub-Saharan Africa, such as Nigeria. It is also the parasite most likely to develop drug resistance .