Compositional flux analysis: We generated all possible compositions from the five employed lipid types, with a resolution step of 5%. We then inserted each composition into a variation of the GARD kinetic equation below, and calculated its accretion flux, as well as the cosine similarity (H) between them. This similarity measure reveals the level of compositional homeostasis, as high similarity means the flux drives the micelle towards its current composition. A successful reproducer is defined as a composition that has an H value of 0.9 or above. Lastly, the typical reproducing composition was generated from averaging the compositions of the ten best reproducers (those with the highest calculated H values). )) 𝐸𝑞. 4