We selected solid detection and turbidity measurements as our system's primary parameters for evaluating mixing efficiency with mechanical agitation. As a first test, a supersaturated solution of acetaminophen (0.46 M) was prepared in 50 mL MeCN at room temperature without stirring (Figure ). The stir rate was increased by 20 rpm every three min to find the minimum effective agitation speed while monitoring turbidity and the presence of solids at the bottom of the reactor. While no solid suspension could be observed below 160 rpm, the onset of solid suspension was visible from 160 to 200 rpm (shown in the turbidity trend). Interestingly, although turbidity reached its maximum value upon stirring at 200 rpm, solids were still detected at the bottom of the flask which did not disappear until 220 rpm, highlighting the importance of analyzing multiple parameters. Other secondary parameters supported this analysis, including homogeneous solution identification and solution color (see SI for details).