Lastly, we examined the influence of cluster size on the probe residence times. For this, we combined all reactions of the same lipid probe type with all other lipid modulators, and calculated typical residence times for all possible cluster sizes. The results depict linear ascent for all probes, ranging from cluster sizes of 2 monomers to about 20 monomers (Figure ). This phenomenon has been demonstrated before in vesicles , explained by a higher packing order of lipids, and was mostly absent in micelles of shorter lipids . For larger cluster sizes, the residence times observed seem to peak between 25-35 monomers, and diminish for even bigger clusters with higher observed variation. This trend could similarly be a result of greater molecular crowdedness in bigger clusters with increasing number of stabilizing hydrophobic interactions . This data expands the previous analysis and demonstrates that variations in the micellar phase, either compositional or size-based, have substantial kinetic effects over exiting lipid monomers.