To describe the products and selectivity of such reactions that involve both iteroselectivity and regioselectivity, it is necessary to express both the iteromeric excess ite and the ratio of regioisomers. Following with the example of the SEAr in Figure , let us consider the reaction of anisole with one equivalent of alkylating agent leading to the monoalkylated products in ortho and para positions (20% and 60% yield, respectively). Both regioisomers correspond to the first iteration, thus the rexp for i = 1 is the combined yields of both products (20% + 60% = 0.8). rnormal is 0.368 (see precalculated Table in the Supporting Information). The result of the reaction for i = 1 can be described completely with ite1 = 100%×(0.8-0.368)/(1-0.368) = 68% (iteroselectivity) and the ratio between all three possible regioisomers functionalized in ortho/meta/para positions is 1:0:3 (regioselectivity). Another example of reactions involving both types of selectivity is the functionalization of oligomeric macrocycles such as cyclodextrins or calixarenes which was studied for decades to seek efficient itero-and regioselective reactions (Figure ). While most reactions to functionalize oligomeric macrocycles are not highly iteroselective or regioselective, some examples stand out and are described in the last section (see below).