From the perspective of Hamiltonian perturbation , one may realize that bonds and electrons are carriers of energy and the primary building blocks. Relaxation of bond length and energy and polarization of electrons dictate the performance of a substance of concern and determine the manner and mobility of proton or molecule motion. It would be necessary to consider the cooperativity, disparity, flexibility, and polarizability of the three-body coupling O:H-O bond that couples the polarizable and flexible H-O dipoles as a unit with ":" being the electron lone of oxygen formed upon reaction taking place . For structure periodicity consideration, the O:H-O is inclusive for inter-and intramolecular cooperative interactions.