Work on modification of solubility parameters continues (see, for example,, ). Authors suggested replacing cohesive energy densities with electrophilicity densities that incorporate the charge transfer effect as a critical contribution to the Hildebrand approach. No fractional cohesion parameters were proposed in this 82 approach. We will discuss the progress related to the transition from one to five-component cohesion parameters models in more detail below, particularly the application of some of these parameters for evaluating the DNA denaturation process.