Many mathematical models have been developed to enhance the understanding of the bone remodeling process. These models primarily fall into two categories for types of effects that they consider: biomechanical and biochemical. Biomechanical models aim to describe how the morphology, structural integrity, and mechanical loading of the bone matrix affect the evolution of bone. Some biomechanical models incorporate individual bone cell dynamics but in a simplified manner. In contrast, biochemical models focus on a detailed representation of the biochemical processes governing bone cell populations.