Aqueous suspensions of POEGMA 28 -b-P(LMA-co-CKA-co-PtxMA) diblock copolymer prodrugs nanoparticles were obtained after dialysis against water. This resulted in nanoparticles with no trace of residual unreacted monomer, as shown by the 1 H-NMR of dried sample after dialysis (Figure ). The nanoparticles exhibited constant average diameters ranging from 77 to 225 nm depending on the type of nanoparticle, and low polydispersities over a period of 1 to 3 months (Figure and b, Table ). Overall, their average diameters were rather well-preserved from DMF to water except, as expected, for PT5 which contained the highest amount of PtxMA units (Figure ). Interestingly, the average diameter and the particle size distribution seem to increase with increasing F Ptx , while the effect of F CKA appears less obvious.