3.1.1. Chiral induction/resolution: if two chromophores, each from the host and the guest successively brought into proximity and the chiral group in the guest forces the chromophores to oriented in a chiral fashion, induced CD signals with the split-like cotton effects are generated, which might be used to assign the absolute configuration of the system based on the signs of the split Cotton effects (mechanism A, Figure ). On the other hand, when the host is racemic, and the chiral guest has different binding affinities to both the enantiomers, two enantiomers are induced to exist in different concentrations, accessed by a conformational selection mechanism by the guest (mechanism B, Figure ). However, for the relatively rigid hosts, upon binding to a chiral guest, a chiral conformation of the host is induced, which is otherwise no detectable in the free state (induced fit mechanism, mechanism C, figure ). 41