Since the interest of this study was the fabrication of a (rapidly) dissolvable triblock polymer formulated with IND (Figure ), blending of both components played a crucial role, especially in regards to obtain and retain both components in the amorphous state to favour a fast drug release and uptake. For the blending process of the polymer and IND, manually grinding and mixing using a mortar was tested, but this proved impractical. The polymer was too viscous and sticky to allow effective blending. In contrast, the low Tg of the polymer makes it a good candidate for HME. Here, only a moderate temperature would be needed during the extrusion process so that the IND can be mixed in. The weight ratio between polymer and IND can be easily altered by using different ratios of the respective compounds in the process.