Although the adsorption of proteins such as albumin, lysozyme, fibrinogen and extracellular matrix components such as fibronectin and collagen has been widely studied , relatively few examples of growth factor immobilisation on polymer brushes have been reported. For example poly(acrylic acid) brushes were functionalised with hepatocyte growth factor and basic growth factor via physisorption and EDC/NHS coupling, for the culture and endoderm commitment of mouse embryonic stem cells . Similarly, vascular endothelial growth factor was coupled to pegylated polyurethanes, to promote endothelialisation . TGF-b was coupled to poly(ethylene glycol) brushes decorating microparticles through azide-mediated Staudinger ligation, using a grafting to approach, to modulate T cell activation . Bone morphogenetic protein 2 was coupled to poly(glycidyl methacrylate) and poly(oligoetheyleneglycolmethacrylate) brushes, to promote osteo-differentiation and bone regeneration . Heparin was also coupled to grafted copolymers of poly(N-isopropylacrylamide-co-2-carboxyisopropylacrylamide), to enable the capture of basic fibroblast growth factor and heparin binding growth factor, for the culture of hepatocytes and hepatocyte sheets . Finally, sulfonated brushes such as poly(styrene sulfonate) and sulfonated poly(3-O-methacryloyl-1,2:5,6-di-O-isopropylidene-Dglucofuranose) have also been proposed for the capture of monocyte chemoattractant protein-1 and the inhibition of coagulation .