Selecting the best models for each threshold individually provides the CV statistics listed in Table (top half). With a combination of physicochemical descriptors from mordred and RDK fingerprints encoding substructural elements of drugs and polymers, nMCC CV and Acc CV values of around 0.8 and AUC CV values around 0.9 are retrieved. These fulfill the requirements for classification modelability (Acc > 0.7 )