As an example of an industrially relevant heterogeneously catalyzed reaction, the partial oxidation of n-butane to maleic anhydride over a vanadium phosphorus oxide catalyst is shown. The simplified reaction network of the highly exothermic process is given in Figure . The molar reaction rates of the five reactions are calculated with the rate equations derived from transport limitation free kinetic measurements by . For the sake of clarity, the rate equations are listed in the supplementary information (SI Section S4). Moreover, the catalyst material properties are adapted from :