Next, another NacNac ligand was explored, the smaller N-mesityl derivative, Mes NacNacZnH. Using this led to 60% of the zincation product, 4 (inset bottom Table ) under the standard conditions. Monitoring the reaction in-situ revealed it was slower than the zincation of 2-methyl-thiophene using 1, presumably due (at least in part) to the lower solubility of Mes NacNacZnH in PhCl (relative to the Dipp NacNac congener). We would note that NacNacZn-Aryl complexes have been shown previously by Crimmin and co-workers to be effective sources of aryl nucleophiles in Negishi crosscoupling and in allylation reactions.