Another bioactive metabolite, 2′-acetoxy-7-chlorocitreorosein (85) which was first recovered from a mangrove-derived fungus P. citrinum HL-5126 demonstrated moderate antibacterial activity against S. aureus and significant activity against V. parahaemolyticus with MIC values of 22.8 and 10 μg/mL, respectively , suggesting that such modification in its structure from that of ω-hydroxyemodin (84) resulted in significant improvement in its antibacterial activity.