Kinetic asymmetry is an essential ingredient of many biological non-equilibrium systems (e.g., microtubule assembly). Our colloidal system is designed in a way to be sensitive to the external stimulus exclusively in the assembled state (negative feedback). That is, only upon assembly, the system absorbs the irradiated energy source; i.e. continuous wave laser in the NIR spectral range (808 nm) (see Figure ). At the laser wavelength, the incoming light is detuned from the plasmonic responses of both components (∼523 nm for AuSs, ∼685 nm for AuNRs) in their dispersed state, thereby minimizing its interaction with the stimulus. Only upon the assembly of the NP mixture, a redshift occurs, increasing the absorbance at 808 nm (Figures ). The rate of aggregation was estimated to be 0.17 min -1 . The unstructured nature of the assembly is further evident in the transmission electron microscopy images shown in Figure . Upon aggregation, the extinction at the laser wavelength (1.9 W) progressively increases that triggers photothermal heating and thus melting dsDNA to ultimately initiate disintegration of assemblies within 2 minutes (see red curve in Figure ). Under these conditions, the rate of redispersion was 10.68 min -1 , considerably higher than the rate of aggregation. Notably, the assembly-disassembly cycles were successfully performed a minimum of 15 times, as shown in Figure and S7, demonstrating high repeatability and minimum losses. Here, the assembly was performed by exposing the AuNP dispersion containing complementary DNA to a temperature of 15 • C (shown in blue in Figure ), while disassembly was conducted using 808 nm laser with a power of 1.9 W (shown in red in Figure ). A delay in the system's response to an external stimulus is critical for obtaining oscillating features, which allows for avoiding monotonous steady states. Although different strategies can be employed to introduce a time delay, hysteresis is one attractive methodology. To evaluate the presence of thermal hysteresis in our system, we conducted reversible assembly under a temperature ramp of 0.5 • C/min, spanning from 10 to 40 • C (Figure ). We observed a freezing temperature (T f ) of 14.4 • C and a melting temperature (Tm) of 22.4 • C under dark conditions. Interestingly, these temperatures were shifted under laser conditions. Specifically, as laser power increased, both the freezing and melt-ing temperatures decreased (see Figure ). Although these shifts are small, analysis performed by following the extinction at 523 nm (corresponding to AuSs) also shows a similar trend of decreasing transition temperatures. These shifts are attributed to the photothermal heat generated by the NPs under laser irradiation. With the presence of additional photothermal heat, more amount of heat needs to be taken away from the system to assemble the NPs, thereby decreasing the freezing temperature. Conversely, less heat needs to be supplied to disassemble the NPs, leading to a decrease in the melting temperature as well. For a detailed discussion on the effect of photothermal heating on transition temperatures, see Figure in the SI. It is noteworthy that at a laser power of ∼135 mW, the system failed to assemble even at 10 • C, that is due to the excessive photothermal heating, emphasizing the critical role of laser power in modulating assembly-disassembly dynamics. With all the feedback mechanisms in place, we investigated the conditions for observing the onset of oscillations. As an initial state, we set a completely precipitated AuNP mixture on the bottom of the cuvette. The solution was irradiated with a CW 808 nm laser with a beam a few mm above the precipitates and with UV-Vis-NIR probe volume located orthogonal to the laser beam. The spectra were recorded at intervals of 2s for 2 hours (Figure ). Under low laser power (∼4.6 mW), NPs remained aggregated since insufficient energy was provided to induce photothermal effects, that is, the extinction at LSPR remained unchanged (Figure -black line). Under high laser power (∼562.5 mW), we observed monotonic redispersion of NPs (Figure -red line). Intriguingly, at laser powers adequate for redispersion, but overwhelming the aggregation of AuNPs (∼134.9 mW), the extinction value at 685 nm exhibited oscillatory dynamics (Figure -blue line). The amplitude of oscillations ∆Ext. was ∼0.02. The oscillating response was further analyzed using Fourier analysis, revealing the major component of oscillation corresponding to a period of 0.028 Hz, or a frequency of ∼36 s (Figure ). These oscillating traces are sensitive to initial and environmental conditions like base temperature and light power.