Comparing these simulations also demonstrates that changing the temperature in the BTA systems has similar effect on the aggregate-size distribution than varying ε in the M model. Increasing the BTA system temperature to 340 K generates an equilibrium size distribution more similar to that obtained in the M system at ε = 40 kJ mol -1 (Figure ). In both cases, relatively small aggregates (average size < 10 monomers) are observed, with significant free-monomer populations, up to ∼ 34% BTA case and ∼ 6% for the M model (more comments on this aspects in the next section). Although these model systems are considerably over-concentrated compared to realistic dilute conditions, thus favoring monomer aggregation, these data suggest a fairly limited tendency to self-assembly. These results are in qualitative agreement with experimental evidences showing a critical transition temperature for, e.g., the BTA motif at ∼ 70 °C (∼ 343 K), above which BTA self-assembly is hindered. Analogous qualitative similarities hold also when the BTA model at T = 300 K and M model with ε = 50 kJ mol -1 are compared, as the spontaneous formation of longer fibers is favored in both cases (Figure ).