Additionally, the direct inclusion of the local symmetry is a challenge as the extracted torsion profiles and their fits are an abstraction layer, which can result in possible mismatches in the identified multiplicity and symmetry. Not accounting for the local symmetry does result in inaccuracies, as e.g. the molecules in Figure will be assigned the same nTABS even though the symmetry of the six-membered ring in the molecule on the left would lead us to expect it to have half as many conformers. However, as we use nTABS to provide an upper limit on the size of a molecule's conformational space, we do not see this overestimation as a significant problem.