Ketene was detectable upon vaping CBN-acetate at vaping temperatures as low, to date, as 278 ⁰C using a dab platform (Figure ). This is consistent with our prior work, wherein ketene was detectable using a pre-filled commercial vape cartridge and a low battery power setting. However, according to theoretical simulations, ketene formation should not occur from vaping VEA, 12 cannabinoid 5 or other acetates at real-world vaping temperature settings.