To obtain parent ILs with MCPA and dicamba anions, a quaternization of 2-[2-(dimethylamino)ethoxy]ethanol with 1-bromohexadecane in acetonitrile was conducted analogously to the previously described procedure using a 100 cm 3 EasyMax reactor equipped with ReactIR ® 15 spectrometer, a reflux condenser, a stir bar and a temperature sensor. The FT-IR spectra acquired in situ were subsequently normalized using Pearson's correction on the entire dataset, and the optimal reaction time was established based on the change in relative absorbance of the band occurring at 919 cm -1 . The obtained hexadecyl[2-(2hydroxyethoxy)ethyl]dimethylammonium bromide was then subjected to the two-step anion exchange reaction according to the previously described procedure. In the first stage, 40 cm 3 of ethanolic solution of hexadecyl ethyl]dimethylammonium bromide (0.1 mol) was introduced into a suspension of 80 cm 3 of the AmberTec™ UP550 OH anionic resin in 100 cm 3 of ethanol. The mixture was stirred for 1 h at 25 °C, and in the next step, the resin was filtered and washed three times with small volumes (15 cm 3 ) of ethanol. The solution of hexadecyl[2-(2-hydroxyethoxy)ethyl]dimethylammonium hydroxide was subsequently neutralized with an equimolar amount of the herbicidal acid (MCPA or dicamba). The solvent was subsequently evaporated using a rotary evaporator. To remove the water formed during the neutralization step for analytical purposes, the ILs were subjected to two-step azeotropic distillation: first, they were dissolved in 20 cm 3 of 2-propanol and the 2-propanol-water binary azeotropewas distilled off before evaporating the excess of pure 2-propanol. To remove the residual 2-propanol, the ILs were additionally dissolved in 20 cm 3 of anhydrous methanol and subjected to another step of evaporation. Finally, the obtained ILs were dried under reduced pressure (5 mbar) at 75 °C for 48 h. Both synthesized ILs were stored under reduced pressure over P4O10 to reduce water absorption.