Malaria has symptoms that are strikingly similar to COVID-19. Plasmodium malaria symptoms are non-specific and include chills, vomiting, malaise, headache, fever, and myalgia. It is extremely difficult to reliably distinguish from other febrile diseases . Plasmodium vivax infection has been linked to severe anemia, respiratory distresss , malnutrition , and coma . In vivax malaria, high fever and chills are more common than in falciparum malaria. COVID-19's early symptoms, such as myalgia, fever, and fatigue, may be mistaken for malaria symptoms . With the same Plasmodium falciparum, infection can range from subclinical to fatal. Malaria, like COVID-19, has both symptomatic and asymptomatic forms . Plasmodium and SARS-CoV-2 have a similar incubation period . SARS-CoV-2 has an incubation period of 11.5 days, while Plasmodium has an incubation period of 7 to 30 days. A few clinical cases of malaria and COVID-19 co-infection have been reported . Distinguishing the two diseases has become extremely difficult in impoverished areas with a high prevalence of malaria.