Yoskamtorn et al. offered a different view of the impact of defects on framework flexibility, looking at the responsive adsorption behavior of defect-rich Zr-based MOFs, of the UiO-67 family (UiO = Universitetet i Oslo). This study demonstrated that the introduction of missing-linker defects led to a strong impact on NH 3 sorption, due to local flexibility of the framework, without overall change in pore volume. Indeed, in situ neutron diffraction and DFT calculations showed that missing linkers resulted in different pore openings and linker dynamics, which are in turn responsible for a marked change in the nature of the ammonia adsorption. We think it relevant to highlight the parallel of these findings with the results of Lee et al. who, in a somewhat opposite approach, demonstrated the impact of "redundant" linkers in multicomponent MOFs in improving the stiffness of the frameworks, allowing them to survive high levels of vacancy defects without alteration of their stability -maintaining framework structure, crystallinity, and porosity.