For the Australian dataset, samples were processed as described elsewhere . In short, 700 μL of urine were drawn into a needleless syringe and dispensed through a 0.2 μM filter. 500 μL of filtrate were transferred into a centrifuge filter with a pore size of 10kDa, which had been washed as per the manufacturer's instructions. Samples were centrifuged at 14000 g for 15 minutes and the filtrate discarded. 450 μL of ultrapure water was added to the filter and the sample was spun at 14000 g for 15 minutes and the filtrate discarded. The washing process was repeated three times.