CrabNet Composition-based property regression Predict performance for proxy scores ElMD Composition-based distance metric Supply distance matrix to DensMAP DensMAP Density-aware dimensionality reduction Obtain densities for density proxy HDBSCAN Density words, DiSCoVeR acts as a multi-objective screening where the promise of a compound depends on both having desirable target properties and existing in sparsely populated regions of the cluster to which it's assigned. This approach then favors discovery of novel, high-performing chemical families as long as embedded points which are close together or far apart exhibit chemical similarity or chemical distinctiveness, respectively" . Table describes the methods used in DiSCoVeR and explains each of their roles.