The last two mechanisms are the conventional single site mechanism as discussed earlier and the ruthenium pathway with protons migrating to the bridge . These mechanisms are illustrated in figs. 3c and 3d and are mainly included as references to allow for better evaluation of the potential LOER active sites. Recent theoretical studies on high entropy oxides showcase the impact of local configura-tion on the reaction mechanism and highlight that a combination of two reaction mechanisms is also a possibility that should be accounted for during screening .