Similar protocols were used to ingest the other datasets, where all original download formats were converted to CSV, so cypher queries can then be used to import data into our Neo4j database. While CTD provides downloadable files in CSV format, in-house python scripts (ClinicalTrials_Prediction) are used to convert UniProt's XML and AACT's pipe-delimited formats to CSV formats. Subsequently, cypher queries are constructed and executed with periodic commit and APOC procedures to populate data in Neo4j. Only manually curated (Swiss-Prot) human proteins are extracted from UniProt. In AACT, the Studies, Conditions, and Interventions tables are used in this study, and these are merged using the NCT_ID unique identifier that is common across these tables. An illustration of intervention associated with a trial from AACT connected with DrugBank, from DrugBank to ChEMBL and CTD, and further, CTD to UniProt is shown as a connected graph in Figure .