Computational modeling has become an indispensable tool for understanding and predicting the behavior of biological membranes at the molecular level. One of the most impactful approaches in this domain is coarse-graining, which simplifies molecular systems by reducing the number of degrees of freedom, enabling the simulation of larger systems over longer timescales . Among the various coarsegrained (CG) models, the Martini force field has emerged as a cornerstone , particularly for studying lipid membranes . Its success lies in balancing computational efficiency with the preservation of essential chemical and physical properties .