Refined weights with small entropy values can already be quite different from the reference weights (Figure ). To illustrate this point, we focus on results for θ = 10 located in the elbow region of the L-curve (see Figure ) and within the regime of gentle refinement. We show the cumulative ranked weights in Figure . For θ = 10, the S KL values are small and range from 0.17 for the doublewell system, over 0.26 for the polymer model, to 0.37 for Ala 5 . In these three cases, the cumulative weights show that the top half of the conformations already have a cumulative probability of 80%, which is quite a substantial change. The relative weight of top ranked conformations further increases with increasing KL divergence.