With increasing CUR loading (10/3), the core size of A-pBuOx-A remains nearly constant while the first and second shell thickness slightly increases for the nanoformulations. This is in contrast to the other to polymer, where core slightly increases at this point.The total micelle radius approaches again 80 Å (Figure A-pPrOzi-A At a CUR concentration of 1 g/L, A-pPrOzi-A exhibits a pronounced core-shell-shell structure with a relatively small core and outer shell, but very big first shell (Figure ). The total micelle radius is roughly 70-80 Å (Figure , D), which is in reasonably good agreement with data from DLS. With increasing CUR concentrations, both the core and outer shell grow, while the inner shell shrinks. Reaching a CUR concentration of 10 g/L, the core dimension increases very profoundly, which is in line with data from DLS .