Moreover, researchers developed a graphene foam/hematite (GF/α-Fe2O3) nanowire arrays heterostructured nanocomposite (HNC) electrode for the construction of an electrochemical glucose biosensor. The graphene foam was synthesized via CVD and provided a large surface area with high charge transfer capacity. Hydrothermal synthesis was used to yield α-Fe2O3 nanowires with an average length of 400-450 nm. The HNC electrode was then modified with glucose oxidase (GOx) for glucose detection. The HNC nanocomposite electrode exhibited a high sensitivity of 20.03 μAmM -1 cm -2 and a limit of detection of 71.6 μM for glucose detection. The performance of the HNC electrode demonstrated that the proposed fabrication method and resulting nanocomposite material have potential for the sensitive detection of various analytes in the field of clinical diagnostics, pharmaceuticals, and biochemical analysis.