We computed the full free energy landscapes of these MOFs using N2O as the oxidant and observed relatively low oxo formation barriers and HAT barriers, suggesting good propensity for C-H activation. Furthermore, the computed energetic spans for these MOFs, which are related to their turnover frequencies, are qualitatively comparable to MOFs with experimentally demonstrated C-H activation reactivity. Nevertheless, our review of the original and related manuscripts describing these MOFs confirms that they have yet to be studied experimentally or computationally for catalysis. Thus, these previously synthesized MOFs, which are also predicted to have the stability required for thermal catalysis, are expected to have favorable kinetics for methane to methanol catalysis, motivating further experimental study.