Another challenge that QSPR modellers face is the reproducibility of results and model deployment. While not specific to QSPR modelling , reproducibility is a topic widely discussed in cheminformatics and computational drug discovery and pertains mainly to correct estimation of real-world performance data, but also the practical transition from model building and evaluation to deployment . For example, the deployment phase also needs to implement crucial steps to process compound structures before prediction to ensure equivalent compound representation as during training. However, currently, there is a lack of open-source tools that would sufficiently address the reproducibility of results and the transfer of models into practice and it is often up to the modeller to provide these, which leads to a large disparity between researchers in how reproducibility and deployment of models is addressed.