Other (chiral) molecules such as carboxylic acids or esters can lead to the obtention of valuable compounds, including chiral intermediates . To this aim, lipases have gained much attention lately as they allow for the enantioselective hydrolysis/esterification (Figure ) and transesterification (Figure ) of poorly water-soluble compounds (i.e. in biphasic media or in organic solvents) . Enzymatic esterification reactions are commonly conducted in non-aqueous solvents, as water accumulation in the reaction medium can promote side reactions (e.g. hydrolysis) and hamper the final esterification yields . Additionally, for enzymatic process, it is well-known that excess water should be avoided to preserve high lipase activity . In lipase-catalyzed esterification, for example, water by-product can be removed in situ from the reactor using membrane technologies. Pervaporation seems particularly suited for such purpose, since it requires significantly lower energy consumption and operating costs with respect to distillation processes 70 . Notably, the pervaporation-aided enzymatic production of monoacylglycerols from lauric and caprylic acid with glycerol, in solvent-free medium, was demonstrated by in 2021. Lipases immobilized on polymeric resins in packed-bed reactor (3 kg scale) operating in recirculation mode, were coupled with two zeolite membranes (in series, 56.5 cm 2 total area) for pervaporation. Such coupled esterification-pervaporation process not only allowed to push the fatty acids conversion towards completion (> 95% after 256 hours), but also afford to increase the relative monoacylglycerols content in the final product (with respect to di-and triacylglycerols). Such study demonstrates the practical applicability of zeolite based membranes for in situ water removal through hydrophilic pervaporation.