Here, we present a proof of principle of implementing semantic web approaches for reporting ENMs, their physicochemical characteristics and their interactions at different levels of biological organisation. It expands the work initiated by where a selection of scientific papers was analysed for ENMs and their connections to AOPs . Twenty-one of the papers investigated in that study were further analysed to extract detailed information about the 83 unique ENMs, their physicochemical properties, and their potential effects. All materials were registered in the European Registry of Materials (ERM) . The registry allows the creation of a persistent, unique identifier for ENMs to enable correct and precise documentation.