In total 218 model reactions were generated for 258 actual reactions, 255 of which had deviations less than 20 kcal/mol (three outliers are analyzed in detail within SI Section 3). This is already useful for many screening applications; however, a MAE of around 5 kcal/mol is far away from reaching the chemical accuracy (i.e., 1 kcal/mol). To achieve more accurate activation energy predictions, one has to either use the TS initial guesses provided by the model reactions to seed TS optimization at the DFT level or use the model reaction predictions as a baseline to train additional correction terms.