The pKa of a palladium-coordinated acetonitrile molecule is defined by equation ( ), which can be viewed as the sum of equations ( ) and (8). Therefore, KA = KB×KC, and pKa Pd- NCCH3 = pKa BH+ -pKeq. The pKa BH+ values for DBU, t BuTMG and P1 t Bu(pyrr) are 24.3, 26.5, and 28.4, respectively, in acetonitrile. The former does not react with the palladium complexes described here to form a cyanomethyl complex to any observable degree while the latter two do so quantitatively, indicating that KB << 1 for DBU and >>1 for t BuTMG; therefore, the pKa Pd-NCCH3 of the coordinated acetonitrile is likely to be approximately 25.