A secondary finding of this study is a steroidal pocket which was noticed for the convergence of 12 drugs to have a similarly pocket on Nsp12 figure , these drugs are (Abiraterone, Calcipotriol, Dexamethasone, Doxercalciferol, Eplerenone, Ergosterol, Estrone, Fludrocortisone, Hydrocortisone, Levonorgestrel, Norethisterone, Digoxin, Finasteride) A statistical study showed that men's cases tended to be more serious than women's (P = 0.035). In the public data set, the number of men who died from COVID-19 is 2.4 times that of women (70.3 vs. 29.7%, P = 0.016). Another cohort study of 31 hospitalized patients showed a significant negative correlation between total testosterone and the need for escalation of care. It's safe to speculate a relationship between sex hormones and COVID19, This study might provide a molecular-based clue into why the mortality in men is higher. After conducting motif search using myhit , it shows that it contains a Casein kinase II phosphorylation site. Thus this study suggests that this binding site is involved in some way in the fact that women are less susceptible and less likely to die form COVID19 than men figure shows the binding site.