κ and their adsorbed Cr 3+ complexes possess excellent proficiency by hindering the growth of pathogenic strains of bacteria at the higher dose level. Computational outcomes revealed that DN and PB compounds are very active and have maximum solubility in the intestine but poor blood-brain barrier penetration. Rhodophyta extracts demonstrated alkaloids, polyphenols, saponins, tannins, steroids, flavonoids, and terpenoids. Whereas the Freundlich and D-R models have proven efficient adsorption of Cr 3+ over κ. Docking studies proved bacterial proteins are inhibited by these molecules.