In this study, a process was utilized to screen a small number of achiral HBAs, both type III and type V DES components, with a large number of chiral HBDs for potential solvent (DES or eutectic mixture) formation. All of the HBA and HBDs in the database are commercially available. The HBA-HBDs were mixed and heated in varying molar ratios, and combinations that remain a liquid at room temperature are recorded as potential chiral DES candidates. The results of the screening are maintained in a publicly available database showing mixtures that form liquids, and more importantly showing mixtures that do not form liquids. The mixtures in the database are compared for the impact of HBA and HBD on liquid formation. Several of the chiral solvent mixtures have been prepared in larger quantities to measure properties, such as water content, density, melting point, and viscosity. The melting point data is used to determine if the mixtures are DES or simple eutectic mixtures.