When gas-phase molecules are deposited perpendicular to a cold substrate (α = 0°), their probabilities of desorption and diffusion are decreased, compared to their probabilities when deposited at an angle. This is because in a perpendicular deposition scheme, kinetic energy transfers more efficiently from the incoming gas molecule to the matrix, speeding the cooling process. When the angle of deposition deviates from normal to an oblique angle, there is an increase in the momentum component of the molecule parallel to the surface and concomitant decrease in its perpendicular momentum. Due to the decreased effectiveness of cooling, the parallel momentum component increases the timescale for surface diffusion and consequently increases the probability that the molecule desorbs from the surface into vacuum. If the incoming molecules diffuse on the surface they can: (a) diffuse long enough for a fresh layer of incoming gases to cover them, (b) interact with surface deformities that aid in dissipating excess energy and cause the molecules to stick to the surface, (c) insert into a substitutional site, and/or (d) desorb into vacuum. While there is not extensive research on the surface morphology of inertmatrix samples during deposition, we endeavor to understand the effects of deposition conditions on the matrix-isolation dynamics through our experimental results.