These ideas are widely applicable to industrial applications of mechanochemistry to lower the monetary cost and environmental effects of reactions at the batch process level. While we assume a one-to-one cost of increasing temperature and generating intra-molecular strain, this is typically not true, where many mechanical methods can be highly efficient compared to heating systems. Attributing these effects in our theoretical framework can typically be done by applying a simple weighting factor that is derived from the cost factor between mechanical and thermal options, whether that cost refers to a financial, energy, or environmental cost. However, the cost function can easily be expanded to consider a variety of controllable variables with the efficiency realized by taking derivatives under those cost constraints.