Together with our recent studies, this work strongly supports further investigations into metal complexes as potential antimicrobial agents. We encourage other researchers to conduct more extensive studies into these compound classes. In particular, future work should focus on more systematic structure-activity relationship studies as well as elucidating the mode of action of active metal compounds. The few in-depth studies on the mechanism of action of metallobiotics in recent years have indicated that metal compounds are likely to affect multiple targets inside of microbes. This makes them well suited to avoid rapid resistance development but also increases the difficulty in narrowing down their exact mode of action. On behalf of CO-ADD we invite researchers around the world to submit their (well characterized) metal complexes for antimicrobial testing to advance our collective knowledge on this promising and underexplored compound class.