Plant material was extracted with three solvents of increasing polarity (hexane, ethyl acetate, and methanol). For each solvent, the dried plant material was macerated 3 consecutive times for 12 hours with a 1:10 (m/v) solvent ratio. The macerate was filtered, and the filtrate was dried using a rotavapor. For the rest of the work, EtOAc extracts were used.