The study presented in (1) on the synthesis of limonene to paracetamol was used as a starting point to assemble a network for analysis. It had found 1068 five-step routes to connect limonene to paracetamol involving 47 unique chemical species. These 47 species were used as query species as they concisely describe the chemical space of interest. Using the Reaxys API all reactions using a given species as reactant were downloaded and saved. This was repeated for the remaining 46 species. Subsequently all reactions were downloaded that listed one of the 47 species as product. All duplicate and incomplete reactions, i.e. reactions that had either no products or no reactants declared in Reaxys, were then removed from the set using a script.