However, in contrast to before MEW printing, there is no obvious residual crystallinity left in the structure directly after printing. This could be confirmed by DSC measurements as well. In the first heating curve of the scaffolds, in contrast to before MEW, no melting peak of IND is visible. After determining the solid-state properties of the drug loaded scaffolds, their dissolution behaviour was investigated. As there is no standardized approach to test the dissolution properties for sublingual dosage forms, the study was done similar to a previously published approach by Lopez and co-workers below the solubility limit of IND in PBS (223 mg mL -1 ). The MEW-processed scaffolds fabricated using the polymer:IND blends of 1:1 and 1:2 (w/w) clearly showed a different dissolution behaviour (Figure ). The samples consisting of polymer:IND 1:1 (w/w), dissolve faster, within about 2.5 min they reach a plateau at 80% released drug after which drug concentration stays nearly constant over the remaining experiment duration. In contrast, the scaffolds of polymer:IND 1:2 (w/w) show slower dissolution, even though almost 75% of the drug is still released in less than 5 min. At this point, we attribute the fact in one case the drug loading levels off at 80% and at almost 120% at inhomogeneities in drug content of individual scaffolds and differences in drug stability for the different drug contents.