The bond fragilities presented in Fig. -11 fall into three separate categories. First one represent the bonding interactions, considerably altered by the process: H4-N1, H4-O3 (Fig. and Fig. ). They show strong maxima/minima in their fragilities that dominate the change in the fragility of respective partner atoms and indicate the critical points on the reaction path, where the process driving the reaction really occurs. The striking similarity between the anharmonicity diagram for the active bonds (Fig. ) and their bond fragilities (Fig. ) proves, the leading role of AB a  over DAB factor in eq. 31.