While IUPAC has defined the term "phenols" , a definition of polyphenols remains yet to be formally accepted. Quideau (2011) explored definitions of polyphenols extensively, providing an applicable description: " The term "polyphenol" should be used to define plant secondary metabolites derived exclusively from the shikimate-derived phenylpropanoid and/or the polyketide pathway(s), featuring more than one phenolic ring and being devoid of any nitrogen-based functional group in their most basic structural expression ." In describing polyphenols in part based on their provenance provides excellent exclusivity. However, one could question whether it is helpful to exclude phenols such as acacetin which have only one phenolic ring. For large-scale cheminformatic purposes, which challenge the application of biosynthesis pathway criteria, an applicable definition may be to treat polyphenols as any molecule with more than one phenolic ring but lacking elements other than C, H, and O.