Fig. The synthesis route of SWCNTs array-GCE catalyst for all three organic compounds sensing, namely Dopamine (DA), Uric Acid (UA), and as well as Ascorbic Acid (AA),reproduced with permission from Copyright @ 2023, Elsevier B.V. So, it explores many methods including the use of enzymes, molecular imprinted polymer (MIPs),antibodies, advanced nanomaterials, and as well as Aptamers. However, the successful sensing must overcome interferences from molecules with a similar redox potential. So, as a conclusion, it is suggested that combining (MIPs) or Aptamers with Electrochemistry promises to achieve fast detection and enhanced selectivity. Suzuki's team developed and characterized a Boron-doped Diamond (BDD) microelectrodes for the in vivo sensing of dopamine. So, a clear signal current response leading medical forebrain bundle (MFB) excitation could be achieved with superior sensitivity. Also, excellent stability reached, indicating that the BDD microelectrode are very promising for the next-generation in vivo electroanalysis. Dopamine constitute a neurotransmitter which plays a key role in the life Science. So, Tang's research team designed and synthesized self-assembled