Compared to the other samples, tickseed flower petals showed the greatest number of polyphenol-related signals with 380 features detected. These features were mainly flavanones (26%), hydroxycinnamic acids (14%), flavones (10%), hydroxybenzoic aids (9%), and flavonols (8%), with 42% of all the features were conjugated with a glycone. The most prevalent features in tickseed flowers were flavanones, especially various isomers of hesperetin-O-glucoside that were in concentrations between 1400 to 6500 µg/g of dry weight . Moreover, the targeted LC-MS revealed that the prevalent classes were flavanones and flavonols, while in the other samples phenolic acids predominated. In addition, the flavanones and flavonols detected appeared in higher concentrations than the polyphenols detected in the other samples. For example, neohesperidin was quantified at 9800 µg/g of dry weight and chlorogenic acid at 7400 µg/g of dry weight, while in moringa leaves, neohesperidin and chlorogenic acid were detected at 2900 and 250 µg/g of dry weight, respectively (Table .11). Overall, it is difficult to compare the polyphenols detected in the tickseed flower petals to other work because to the best of our knowledge, no previous investigation of polyphenols in tickseed flower petals exists, either targeted or untargeted.