Having established the accuracy of the mPB equation for ionic density profiles, we proceed to include CR to investigate how variation of pH influences the nanoparticle charge and the osmotic pressure inside the suspension. All the results presented in this section have been obtained for nanoparticles with Z = 600 weak acidic sites and size a = 6 nm. For very high pH the acidic groups become completely deprotonated resulting in nanoparticles with surface charge density of σ ≈ 212.2 mC/nm 2 .