Where α is number of moles of TEOS, β is the number of moles of NH 4 OH and γ is the number of fractionated additions of TEOS. The parameter estimates for the equation are shown in Table . The model was found to agree well with the data, with an r 2 of 0.68 and RMSE of 0.089 (Table ). ANOVA demonstrated the model was highly significant with a p-value of <0.0001, illustrating again that, overall, the experimental factors directly impact the monodispersity of the produced particles, hence, H 0 was rejected. A plot of actual vs. predicted response of particle dispersity, determined from the regression analysis, is presented in Fig. .