Electronic binding energies (∆E) of these data were calculated at the r 2 SCAN-3c 36 and GFN1-xTB 50,51 levels, making them suitable for ∆-ML. Knattrup et al. fully trained from scratch. Figure shows that the two methods (red and brown lines) are sensitive to the choice of the first 0.25k data but perform quite similarly after a few iterations.