The clustering analysis confirms this finding; five high-dimensional HDBSCAN*-detected clusters are found across the landscapes (Fig. ), each comprising several different isomers. By comparing with Fig. , where the structures are coloured by the heuristic structure classification (Fig. ), it is clear that γ is the most common crystal packing adopted by the full set of molecules. This dominant cluster is also identified by the HDBSCAN* method, with good registry between the automatic clustering (cluster 3, dark blue in Fig. ) and heuristic classification (yellow cluster in Fig. ). The fact that automatically-detected structural motifs, as well as heuristic packing classes, comprise crystals formed by different molecules and also by molecules with different point-group symmetry suggest that both from the point of view of local environments (as detected by the SOAP-REMatch) and from the point of view of the stacking, there is no obvious relation between molecular symmetry and preferred packing.