Transcription factor zinc-finger (IPR027392) is a zinc-finger domain of transcription factor. Prokaryotic dksA C4-type zinc finger profile (PS51128) is a dksA C4-type. In bacterial cells that lack amino acids, guanosine tetraphosphate (ppGpp) or alarmone serves as a catalyst for a variety of regulatory processes. ppGpp specifically inhibits the activation of stable RNA transcription promoters. It regulates the activity of RNA polymerase by binding directly to the catalytic site, it regulates RNA polymerase activity. By binding to the enhancer ppGpp RNA polymerase, Dksa regulates signaling. Additionally, ppGpp and dksa regulate the promoters of enzymes involved in amino acid biosynthesis.