In total, 6220 MMPs were identified within the dataset of 2065 compounds described above. As a result of the significantly higher number of non-lysosomotropic compared to lysosomotropic compounds in the data set, many more MMPs are found in which both compounds are non-lysosomotropic, compared to the other two cases. For 956 MMPs the lysosomotropic property is altered upon the respective transformation, i. e. the lyso score threshold of 75 is passed.