Looking at the P-score column it was apply to accurately rank order generated poses for all ligands independent from the starting point of the binding site. Also, in the case of 7JIV in the apo-opened conformation simulation, the Pscore was able to identify it as "NA" (Not available) which refers to no poses were prioritized in these simulations, eliminating the false positive predictions made by FMO or residence time as a single descriptor.