The RMSE and MAE for the ninth group i.e. misc (molecules not categorized in any of the previous eight groups) show the highest deviation in the prediction with their values of 0.86 and 0.54 kcal/mol respectively. But the correlation metrics i.e. R 2 and P r show different behaviour than the error metrics. The correlation metrics for this group (R 2 = 0.9 and P r = 0.95) indicate that this group's performance closely agrees with experimental hydration free energy. These two contradicting metrics show that there is a systematic error in the model both in the training and testing phases. The same contradicting trend is also observed in the case of aromatic group. Except for these two groups, our models perform well across different groups with relatively low RMSE (less than 0.53 kcal/mol) and low MAE (less than 0.36 kcal/mol). For the correlation metrics except for alkanone group, all other groups are highly correlated with their corresponding experimental hydration free energy. The R 2 is always more than 0.85 and P is always greater than 0.95 except for alkanone group which signifies the performance of our model across the groups.