By scanning the binding site using the probes library we can highlight the percentage of interactions divided into bond types between the probes and each residue. For example, His-A-449, is highly accessible with moderate favorable interaction energy and bond types can be hydrogen bond, with fewer accessibility for Pi-Pi stacking, Pi-cation stating and salt bridges, (Figure . A.). This not only show the type of interactions but also the accessibility of which pharmacophore feature is more dominant per single residue.