The ortho substitution also allows the reaction to progress to a certain extent (1g, F, 35%). For the meta substitution, a single regioisomer, with cyclization occurring at the less sterically hindered site, is identified. A reduction in the reactivity is observed as compared to the para substitution (1h, Me, 56%; 1j, F, 38%). The electron-donating methoxy substituent (1i, 42%) also provides a competent substrate. The meta, para disubstitution (1k, m-Me-p-Me, 54%) manifests the reactivityattenuating effect of meta substitution.