Procedure A for the Synthesis of Iodohydrins 3. Based on a literature procedure. N-iodosuccinimide (1.1 equiv.) and distilled water (1.0 M with respect to the olefin) were added to a mixture of olefin (1.0 equiv.) and ammonium acetate (0.1 equiv.) in acetone (0.25 M with respect to the olefin). The reaction mixture was stirred in the dark at room temperature. Upon completion as indicated by TLC, the mixture was concentrated in vacuo, and the residue was redissolved in water and extracted with ethyl acetate (3 × 10 mL). The combined organic layers were washed with an aqueous 10% solution of Na2S2O3, dried over anhydrous Na2SO4, filtered and concentrated in vacuo. The crude was purified by column chromatography to afford the wanted iodohydrin.