Amphidynamic crystals are solid-state materials known for their ability to allow molecular rotational motion within a wellorganized crystal framework. The presence of rotational dynamics in the free local space of crystalline media is a defining feature that sets amphidynamic crystals apart from more densely packed general "static" crystals (Figure ). The presence of rotational dynamics can impact both the crystal structure, including molecular orientation and symmetry, as well as bulk crystal properties such as thermal expansion and phase transitions, macroscopic motion, electromagnetic, optical, and photophysical properties. These properties have allowed to place amphidynamic crystals as a promising direction in the fields of solid-state molecular machines and stimuli-responsive functional materials. The precise control of luminescent properties in solid-state materials has attracted much attention because of the potential for the development of functional materials such as sensors and external field-responsive devices. Recently, several types of amphidynamic crystals were demonstrated for controlling solidstate emission and sensing inclusion of organic vapors or solvents in solid-state porous materials. The emission properties in the amphidynamic crystals were found to be strongly affected by internal rotational motion. The presence of rotational motion in the crystals can cause reorientation and variation in the conjugation of the luminophore moieties, facilitating access to the conical intersection between excited and ground states, causing emission quenching and excited state decay through a nonradiative relaxation pathway (Figure ). Conversely, the restriction or inhibition of molecular rotation should enhance the photophysical performance, making this phenomenon akin to aggregation-induced emission (AIE). While the presence of thermally activated molecular motion is usually an unwanted feature for solid-state luminescent materials, in the case of amphidynamic crystals, their rational design allows for the finetuning and precise control of rotational motion. This results in emerging thermo-responsive luminescent properties, allowing control over luminescence intensity, lifetime, and color through the rate and mode of thermally activated rotational motion. Taking the knowledge of the molecular motion effect on photophysical properties in solid state, our group seeks to establish the connection between molecular rotation and solidstate chiroptical properties, such as Circularly Polarized Luminescence (CPL). The CPL is defined by the difference in intensity between left-and right-circularly polarized emission (ΔICPL = IL-IR) and the capability for it is evaluated by the luminescence dissymmetry factor (glum = 2[IL -IR]/[IL + IR]). The control of ΔICPL and glum is one of the key targets in the development of functional CPL materials because of the potential in stimuli-responsive emission sensors, 3D displays, and security devices. There are many examples of modulation of the CPL (both ΔICPL and glum) achieved by utilizing fluid media, such as solution, dynamic polymer or aggregate environment, while there are still limited examples in the well-ordered and rigid crystalline media. The glum of molecules showing CPL is generally affected by the asymmetric geometry and orientation of the molecular structure. It is known that molecular rotation may lead to the alteration of symmetry in crystalline materials, which is highly important for chiroptical properties. Usually, the acceleration of molecular rotation in crystal with temperature elevation leads to the increase of the symmetry of the system what can be manifested not only as dynamic disorder of molecular fragments but even as whole crystal symmetry change and phase transition (Figure ). Moreover, previously, Liu et al. reported the possibility of CPL quenching by molecular motion in the solid state on a similar basis to the reported non-polarized emission in amphidynamic crystals. Recently, our group reported an example where fast rotational motion in triaryltriazine crystalline rotors induces conformational changes in chiral binaphthyl substituents, thereby affecting circular dichroism (CD) and CPL responses. Nevertheless, the current state of solidstate CPL research still cannot provide a comprehensive understanding of the relationship between the effects of rotational motion on crystal structure and symmetry, and chiroptical properties.