Gamma-aminobutyric acid (GABA), a neurotransmitter, is secreted by neurons within the Nucleus Accumbens (11). This secretion acts primarily as an inhibitory mechanism, moderating dopamine release (11). Elevated dopamine levels typically induce euphoria; however, GABA's modulatory role prevents excessive dopamine release, thereby regulating this euphoric response (11). Opioids, known for their analgesic properties, concurrently inhibit the transmission of nociceptive signals and the release of GABA by GABAergic neurons (11). This inhibition allows dopaminergic neurons to release substantial quantities of dopamine, culminating in heightened euphoria (11). This mechanism underlies the profound addictive potential of opioids, rendering countless individuals dependent and unable to cease usage (11).