Finally, we examined if the surface-bound polyelectrolyte can also be exploited for conveying information dependent on pulse arrival time. 8 Fig. shows a sequence of hypothetical input pulses with a fixed duration, d, and a decreasing interval between them 𝜏𝜏. Inspired by approaches commonly applied in neuromorphic computing, we created a temporally sparse input (with the pH based on the results in Fig. ). Fig. shows the input spikes as pulses wherein the pH was changed from 7 to 9, initially with a duration, d1, and an interval, 𝜏𝜏1, of 7.5 min (indicated with i) and subsequently with a duration that was half of its original value (d2=d1/2) and a decreasing interval, 𝜏𝜏2, from 2d1 to 0d1 (indicated with ii). We thus examined how the increase of the frequency between the pulses could establish an event-driven output. The output corresponding to the pulse sequence d1 is fluctuating irregularly, with local maxima between 18-40% transmittance, but nonetheless shows that PECs are formed at an interval similar to 𝜏𝜏1. PECs, however, cannot form if the duration is changed to d2. No response occurs in the system, unless the duration between pulses was decreased to 𝜏𝜏2=d1/2. The original signal was restored at 𝜏𝜏=0d1. Hence, PEM-coated channels can be used to examine a complexation process that is defined by the shape of the input curve, opening routes for modulating dynamics-encoded in the frequency and duration, or other features, of a temporal signal-of other biologically relevant processes.