The rapid evolution of e-fuels underscores the importance of a comprehensive life cycle assessment (LCA) to understand their true environmental implications. From raw material acquisition, production, use-phase emissions, to end-of-life considerations, it is evident that while e-fuels present a promising solution to decarbonizing the transportation sector, their sustainability is contingent upon a multitude of factors. As evidenced by various studies from 2020 to 2023, advancing technology, policy, and stakeholder awareness can potentially steer efuels towards becoming the sustainable energy solution of the future.