We believe in picking the best hardware for the job and in replacing humans only when it makes sense. We haven't seen for example a exible and ef cient solution for dosing a large variety of different liquids on a small scale and none for sampling from often heterogeneous reaction mixtures at less than 50 uL total volume. Therefore, we perform these steps manually using multi-channel and electronic pipettes respectively. This results in a partially automated work ow that is simple, robust and highly productive.