The combination of molecular switches or non-covalent interactions with catalytic units within the same (macro)molecular scaffold led to the advent of dynamic catalysts for the temporal control of catalytic reactions. Amongst this emerging area, selecting the configuration of the generated stereogenic element in a predictable manner is a current challenge that has been achieved by a limited number of reconfigurable catalysts. In the most-employed strategies, the intrinsically achiral catalytic unit is connected to a molecular, macromolecular, or supramolecular chiroptical switch, leading to pseudoenantiomeric states upon activation of the switch by a suitable stimulus (Scheme 1a1). These switchable asymmetric catalysts have been exclusively employed for the generation of chiral molecules having opposite configurations, i.e. enantiodivergency.