Integrase-type (IPR003308) is a retroviral integrase that allows DNA copies of the viral genome to be integrated into the host chromosome. Three domains comprise integrase: the N-terminal zinc-binding domain, the central catalytic core, and the C-terminal DNA-binding domain. We refer to the central catalytic core and N-terminal zinc-binding domain of retroviral integrase as integrase catalytic and integrase zinc-binding, respectively.