Figure : Paclitaxel Tetracyclic Core Numbered is a series of prompts aimed at replicating three types of generative AI queries. Prompt OHA1 is the time it would take a human researcher to analyze and write an answer of similar length to a GenAI response. OHB1 is an estimate for how long it would take the fastest human to read a 6,322 word summary and write a 250 word response, and Prompt OHB2 is the time required to answer a direct prompt based on human insight. Table illustrates the sequence of times provided by ChatGPT-4o. The time associated with Prompt OHB1 was chosen as the standard for the manuscript due to being the fastest time of the three prompts tested, which gives the speed benefit to the human. A direct comparison between Prompt OHB1 at 1,380s and generative AI times is as follows: a) OHB1 vs. slowest B1 generation time of 54.84s = optimal human is 25.16x slower, b) OHB1 vs. fastest B1 generation time of 11.74s = optimal human is 117.56x slower. provides the ChatGPT-4o breakdown of each step required by an optimal human to provide a paclitaxel retrobiosynthesis based on the OHB1 Prompt and the attached 10 Paper Summary seen in Appendix A. Important steps cited by the model were Reading the Text for 5-7 minutes which highlighted the nature of scientific material and "Skimming while taking brief notes", Analyzing and Identifying Relevant Information for 8-10 minutes while "the researcher consolidates information and decides what is most critical", Citations for 3-5 minutes, and Typing the Response for 7-8 minutes.