By combining our feedback control based on visual cues with the temperature control of an EasyMax, we sought to perform temperature cycles on a solution of acetaminophen in MeCN to measure its solubility and MSZW, as depicted in Figure . The binary homogeneity determination was the primary parameter used by HeinSight2.0 to detect the onset of nucleation and dissolution (via cloud point and clear point determination, respectively). The quantitative turbidity trend served as a secondary parameter to corroborate the data. The results of the cooling crystallization are demonstrated in Figure .