The current SPL standard and XML schema is based on SPL release 8. An upgraded release 9 had been prepared several years ago, which was specifically enhanced to provide full support for PQ/CMC requirements. For various reasons this had not been moved forward, because the only people with the requirement suddenly decided to do everything in a completely different way. No PQ/CMC standard had been moved to any sort of implementation for many years since that decision was made, and whatever had been discussed for an alternative standard is far from capable of dealing with the chemical phenomena the way that SPL does. Now, what this means for R-SPL is that most of the use cases we have shown so far in this paper are handled by the current SPL release 8 schema, but we will release a draft for trial use (in one form or the other) of SPL release 9 with the PQ/CMC enhancements, and possibly with a few more edits found useful for full support of all advanced reaction SPL requirements.