Copper is a common transition metal and ranks among the three most extensively used heavy metals worldwide. It is abundant in nature. Despite being recognized as hazardous, copper serves as a crucial 50 element in the biochemical processes of human cells, contributing significantly to enzyme synthesis, bone regeneration, and tissue maintenance. Naturally, copper have three forms: Cu (metal), Cu + (cuprous ion), and Cu 2+ ions, with Cu 2+ being the most dominant and hazardous in the environment.