CRISPR/Cas is also considered as the leading site-specific nuclease for plant genome editing, first reported in 2013 by Not only is it useful to develop crops that are high yielding and resistant to abiotic stresses (drought, salinity, flooding, etc.) exacerbated by climate change, but also to resist biotic stresses such as insects and pathogens that are also being exacerbated by climate change. Our original search query resulted in a considerable number of documents, specifically around 13%, related to the application of CRISPR in plants and for agricultural use. The use of CRISPR in agriculture is beyond the scope of this manuscript and the related documents were filtered out of our dataset. For more information on the application of CRISPR for the enhancement of disease and parasitic plant resistance in crops and/or for climate change resilience we suggest reviews by: Jhu et al., Paul et al.,