Accordingly, CD measurements of pEtEtOx and pPrMeOx series homopolymers were performed between 200 and 255 nm in methanol solution (0.1 g/L) at 25 °C. A positive Cotton effect (CE) with maximum values between 210 and 220 nm was observed for the S-homopolymers while a negative CE was observed for the R-homopolymers. This is in the wavelength range of n-π* transition of the amide chromophore (Fig. c and d). The opposite CE and almost symmetrical CD spectra of R-and S-homopolymers indicate that they have a similar helical conformation as proposed by Oh et al., but with opposite handedness. The racemic polymer and the 1/1 (w/w) mixtures of two corresponding chiral homopolymers did not show CE.