Zirconia nanotube (ZrNT) is a promising candidate for such delivery coatings on implants and can serve as an alternative to other extensively studied potential nanostructured biomaterials like nanoporous anodic alumina (NAA) and titania nanotube (TNT) ] owing to similar fabrication strategies and innate intrinsic properties as mentioned in the preceding text. Zirconia as a biomaterial was introduced along with other classes of high-performance ceramics as an alternative to address the drawbacks of alumina in orthopedic applications [ due to its chemical inertness, biocompatibility, and mechanical strength[ ]. In dental implants Zirconia is particularly considered more suitable due to favorable properties such as white coloration, translucency, and generally good aesthetics[ . A highly ordered array of ZrNT can be fabricated by electrochemical anodization of Zirconium in a fluoride-containing electrolyte with a defined dimension and geometry[ ].