We are also interested in the impact of our REMD-EVB simulations on average execution time per trajectory and simulation length, compared to our conventional EVB simulations. This data is summarized in Table , with all simulations being performed on two 32-core Intel Xeon Gold 6130 CPUs. From this table, it can be seen that a single conventional EVB trajectory of a length that is typically adequate to obtain convergent simulations, as in our prior work ,