Blowers and Masel have highlighted that the applicability of BEP relations becomes limited in cases of highly exothermic or endothermic reactions because it can lead to negative activation energies and poor estimates. They derive a new form of expression we term the Blowers Masel Approximation (BMA). The derivation follows from a few approximations, each of which they supported with detailed quantum chemistry calculations. First, consider an abstraction reaction of the form