Detailed synthetic information, including LC-HRMS, MS-MS, and NMR of linear and cyclic peptides can be found in Supplementary Fig. . f, Incorporation of both 2 and Kynurenine into a single IVT peptide ivt.LP5 and subsequent Friedländer cyclization into ivt.CP5. g, Extracted ion chromatograms of ivt.LP5 and ivt.CP5 and comparison with an authentic standard prepared using solid phase methods.