Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) properties were calculated for the VS data set, generated by the assembly of focused and commercial libraries (see Section 2.7). This was accomplished using ADMET-AI, utilizing the Python library for local predictions. ADMET-AI computes eight physicochemical properties with RDKit and predicts forty-one ADMET properties through its Chemprop-RDKit graph neural networks.