In summary, the new strategy for the AIE/ACQ control is devised in the present study, exploiting the subtle balance between two different electron-donating/electronaccepting substituents. The modification of the topology of the fluorophore carrying methoxy group provides the effective switching of the emission in the wide range of FQY values yielding bright fluorescence in aggregates and/or solid- and in crystal estimated with ALMO-EDA approach within ωB97X-D/aug-cc-pVDZ for regioisomers 3 and 7 and the dimethylamino derivative (black points denote the total interaction energy, green bars correspond to the electrostatic component, cyan ones -to Pauli term containing exchange and dispersion part, magenta -polarization energy, dark blue -charge transfer contribution and grey in excited state is the excitonic splitting effect) state. In addition to the previously proposed approaches relying on doubly substituted regioisomers with one type of substituent for crystal packing alterations and substitution by bulky groups for the minimization of internal motion restrictions, current approach opens the plethora of possibilities of simple topology modifications for new effective photoresponsive molecules.