Fluorogenic probes, which refer to probes that can stimulate their emissions upon target recognition, represent a significant advancement in the pursuit of site-specific imaging with minimal background signals. This milestone has been accomplished through the application of fluorescent quenching pathways. For example, by linking an emission quencher to a fluorophore, the resulting fluorophorequencher complex exhibits negligible emission. When the quencher is removed in response to specific biological events, the fluorophore's emission is restored, resulting in turn-on emission. This characteristic defines the fluorophore-quencher complex as a fluorogenic probe. To enhance contrast and achieve site-specific signals with these fluorogenic probes, the identification of easily removable and highly effective emission quenchers is essential.