and HCO2H as additives, and 5 mol% of PC, the literature yield using PTH (94%) was higher than that achieved by us (77% Table , entry 1), likely owing to the different reaction times (72 h vs 18 h, respectively). However, since most literature reports use only an amine as the additive (Figure ), which is often DIPEA, the reaction conditions were modified to omit the acid and replace NBu3 with DIPEA, resulting in a 42% yield with PTH (Table , entry 2). As the DMAC-TRZ derivatives are not soluble in MeCN, the solvent was changed to DMF, giving a 78% yield (Table , entry 3). Finally, at a reduced PC loading of 1 mol% of PTH, the yield decreased to 61% (Table , entry 4).