In recent times, the drug development sector has shifted its attention towards the creation and synthesis of small molecules for their potential as Here, MW is the molecular weight of the drug, logP represents lipophilicity, nHBA is the number of hydrogen bond acceptors, nHBD is the number of hydrogen bond donors, and nCH is the number of H of CH. Figure illustrates the EHBP* calculated by both equation ( ) and ( In summary, MESP analysis holds significant promise for drug discovery.