Beyond band gaps, it is well-established that different DFAs can change how the charge density is distributed in a given material. Furthermore, partial atomic charges (which can be computed directly from the underlying charge density) are commonly used in molecular simulations of MOFs and can be used to interpret trends when modeling redox processes and chemical reactions. One such method to compute partial atomic charges, the sixth-generation Density Derived Electrostatic and Chemical (DDEC6) partitioning scheme, has found widespread use in molecular simulations of MOFs 89 (e.g. for gas storage and separations) and has performed well in tests of reproducing the electrostatic potential. To explore the sensitivity of partial atomic charges to different DFAs, we compared ~960,000 partial charges calculated from the DDEC6 method using charge densities at the PBE, HLE17, HSE06 * , and HSE06 levels of theory. As shown in Figure , the DDEC6 partial atomic charges calculated by PBE and HLE17 are highly correlated across the entire dataset, with most points falling within 0.04 charge units from the line of parity. When investigating the computed partial charges by HSE06 * , we find that the HSE06 * partial charges are even closer to the PBE reference than the HLE17 partial charges are (Figure ), indicating that 10% HF exchange at small interelectronic distances does not substantially change the first moment of the charge density. However, when increasing the HF exchange to 25% with HSE06, a slightly larger difference can be observed (Figure ).