relationship between the rate constants: Models that violate tenets of chemical equilibrium such as those shown in Scheme 11 lack experimental realism and cannot provide insight into autocatalytic processes for the emergence of homochirality. A potential "fix" to this conundrum has been suggested by proposing that an external source of energy could drive one but not the other of the reactions shown in the models of Scheme 11. Goldenfeld has informally termed this refinement of reversibility models for autocatalytic amplification of ee as "pigs can fly, with jetpacks," 53b introducing an external energy source (the "jetpack") that pushes the autocatalytic system to homochirality under reversible conditions. These authors chose not to define the nature of the external energy source, stating that it "obscures the basic mechanisms leading to homochirality." 53b However, this discussion Goldenfeld points out that any externally driven reaction that is far from equilibrium violates detailed balance and microscopic reversibility and that this is necessary for the emergence of homochirality. Indeed, this is a trivial point: any chemical reaction is necessarily not in equilibrium when it is operating under productive conditions. Microscopic reversibility and detailed balance only hold when the system is in equilibrium, but the conditions set by chemical equilibrium -even if this is an aspirational condition -will define the relationships between the rate constants, and those rate constants hold under non-equilibrium conditions. Jet-packs cannot overrule chemical thermodynamics.