Besides covering a large range of "typical" nano-and advanced material classes and synthesis mechanisms, these examples were chosen due to their high relevance in many areas and current and future applications. Since one striking advantage of an automated robotic synthesis platform is the high reproducibility of the chemical syntheses, such a system is ideally suited for areas requiring consistent and reproducible nanomaterial production, such as application as sensor materials, in life sciences, or as reference materials. Therefore, gold nanoparticles (NPs) and Stöber silica NPs were chosen for detailed reproducibility studies as reference material candidates. The other nanomaterials cover various other relevant use cases and were also studied for reproducibility. Specifically, those are i) mesoporous silica NPs which are often used in catalysis and for triggered release applications , ii) metal organic frameworks (MOFs) for gas storage, catalysis, and sensing , iii) copper oxide NPs (CuO) for antimicrobial applications , and iv) core shell particles, specifically, copper oxide coated with a silica shell (CuO@SiO2) and gold coated with silica shell (Au@SiO2) .