Next, we subjected 4-BrPyCN to different aprotic solvents ranging from highly polar, dimethyl sulfoxide (DMSO), to least polar, toluene (Table ). We specifically screened for aprotic solvents due to incompatibility of sodium hydride (NaH) with protic solvents. We observed Py-N-ene only in strongly polar aprotic solvents (entry 1, 2, and 3 in Table ), Table . Screening of structural analogs of 4-BrPyCN for the formation of Py-N-ene.