The scope of the one-pot method to convert simple arenes into trapped arynes was evaluated with ten different arenes and nine different arynophiles (Scheme 2). Six of the arenes used in the one-pot method had also been previously used in our two-pot method (1a-d, g, i; Scheme 2). In four of the cases, the yield is higher in the one-pot method than the two-pot method by 6-24% (3aa, 3ba, 3da, and 3ia; Scheme 2). In the two cases in which the yield is not higher for the one-pot method, it is within 5% and the greater efficiency and reduced waste of the onepot method make it preferable (3ca, 3ga; Scheme 2). Several new arenes were also evaluated in the one-pot method including 2-cyanoanisole (1e), a benzoimidazolone derivative (1f), and trisubstituted arenes (1h and 1j; Scheme 2). A range of different arynophiles were also compatible in the one-pot procedure, including those that undergo [3+2] cycloaddition such as benzyl azide 20 (2b) and a nitrone (2c); as well as those that participate in [2+2] cycloaddition such as cyclic enol ether (2d) and cyclic enamine (2e; Scheme 2). The later reaction converts simple arenes into densly functionalized racemic benzocyclobutenes (3cd and 3ae; Scheme 2). Amines are one of the strongest arynophiles known, and are compatible in this one-pot procedure. Both aromatic and aliphatic (2f-h) amines trap Scheme 2. Scope of one-pot net dehydrogenation of arenes.