Innovation is inversely related to the maturity of the research in any discipline. The conventional methodology of empirically and sequentially testing a limited number of samples is time-consuming and highly suppositious. In contrast, the remarkable efficiency of highthroughput experimentation (HTE) provides for an alternative perspective outside the conventional practices as well as condensed experimental time to achieve systematic insights, leading to quicker discoveries. The key advantages of process automation and parallelization can generate reliable and consistent datasets in a short time of period. One of the first outstanding instances of the systematic screening of libraries was the discovery of the first ammonia synthesis catalyst at BASF by Mittasch et al. in 1909. The pioneering work of J. J.