The study came to the conclusion that the TNF-α and NTP-proBNP proteins were precisely bound by the aptamer's molecular docking and logical design. Mutations in aptamers have also been carried out based on these docking results. These TNF-α-M4 mutations have the potential to improve significantly TNF-α detection, which would help with early identification and monitoring of heart conditions like AMI. The paper notes that although the results are encouraging, more experimental validation is required to verify the computational conclusions.