We will summarize the working principle of the three main functionalities of the Jammy Key framework: Jammy Key for Configurational Sampling (JKCS), Quantum Chemistry (JKQC), and Machine Learning (JKML). Additionally, we will discuss how the Jammy Key framework is used to create an improved database for atmospheric clusters (ACDB 2.0). Figure : Schematic diagram of the bottom-up approach for conformational sampling. Figure has been adapted from the dissertation of J. Kubečka.