The kinetic sensitivity results on the base models identified that CH 4 conversion is most sensitive to the adsorption of CH 4 and O 2 , so the kinetic sensitivity screening encompassing CH 4 conversion, synthesis gas, and full oxidation yield across the set of 81 metals was centered around these two reactions. As shown in Figure , increasing the reaction rate of CH 4 + ⇤ * ) CH 4 ⇤ causes an increase of CH 4 conversion for both the CMPO and CMPO-BMA models on metals with carbon binding energy weaker than 6.75 eV. On the contrary, the metals on the left of the heatmap, in the column where E C = 7.0 eV, demonstrate strong negative sensitivity in all the maps in Figure . The surface-to-carbon bond grows stronger from the right to the left of the heatmap, making it harder for carbonacious species to leave, leading to a higher coverage of carbonacious species. When the coverage is too high, the overall reactivity of the metal can be increased by slowing the adsorption reaction CH 4 + ⇤ * ) CH 4 ⇤) (negative sensitivity). When coverage is low, however, increasing the rate of adsorption increases the rate of reaction (positive sensitivity). Therefore, the pixels on the left of the heatmap have reversed sensitivity compared to the right side. The same trends can be observed for sythesis gas and full oxidation yields in Figure and.