In this report we present our findings resulting from analysis of more than 250,000 publications in the field of nanosensors spanning a period of two decades (2003-2203) extracted from the CAS Content Collection , one of the largest repositories of scientific information. We have examined the landscape of published research in nanosensors to provide insights into the types of nanosensors as well as the common nanomorphology utilized. This, in combination with our access to CAS Registry 12 , enabled identification of emerging materials across various substance classes (polymers, small molecules, elements) associated with nanosensors. Our analysis indicates that a major application of nanosensors appears to be biomedical in nature including in cancer diagnosis and testing and drug discovery, other applications of importance are in agriculture and food industry. We also provide a snapshot of commercial interest in the development of nanosensors for a wide range of applications. It is our hope that this report provides a comprehensive overview of the field and serves as a valuable guide to researchers/scientists.