The entire system is conveniently located on a standard laboratory benchtop and is enclosed within a custom-designed, closed suction box, eliminating the need for placement within a fume hood during reaction runs. The system's design facilitates three distinct operating modes: (i) Single experiment: Conducting a reaction under specific conditions, whether for the purpose of yield/productivity discovery or as part of a scope entry. (ii) Self-optimization: Automating the optimization process for a single reaction or multiple reactions consecutively. (iii) Scale-up: Exploiting the optimized conditions obtained through self-optimization for efficient scaling up of the reaction.