With the release of Martini 2 , it became possible not only to expand the library of phospholipid models , but also to include new lipids such as sterols and glycolipids , as well as proteins , nucleic acids , carbohydrates , and other biomolecules . Over the years, Martini has been used in a wide range of membrane-related applications, including domain formation , complex membrane compositions , membrane remodeling , protein-lipid interactions , and permeability . These studies have provided crucial insights into biological processes at the mesoscopic scale, bridging the gap between atomistic simulations and experimental observations and enabling in-situ simulations of membranes in the context of a realistic cellular environment .