The output DW docking-scores were generated in unit-less relative values expanding from -20 to -130. To convert FtsZ DW docking-scores to nM units, the 100-30000 MIC range data obtained from the Chembl bank were converted to nM and then correlated with the unit-less DW docking-scores by polynomial fitting (Figure , red continuous curve). To obtain ~ MIC nM values for the lower DW docking-scores, the polynomial curve was linearly extrapolated to minimal 1 nM MIC as previously suggested , and to the corresponding minimal -130 DW docking-score observed during our preliminary docking data (Figure , red dashed line). To estimate their corresponding docking-scores (ds) expressed as ~Kd values, the polynomial and the extrapolated values were exponentially fitted by the formula kd=1507-(1331*EXP(-0.001*ds)). The resulting data were then converted to ∆G energies in Kcal/mol by the formula ∆G = 1.4*(log(Kd*10 9 )). DataWarrior Ligand Efficiency (LE), LLE lipophilic LE and LE lipophilic Price (LELP) parameters were calculated from ∆G taking into account the estimated maximal -1.5 Kcal/mol affinity reported before .