Interestingly, all five samples with a high R 2 were stored at the same pH and for these storage conditions, the %LC was less than or equal to 80% at the 24-month time-point. All other pH storage conditions had a %LC greater than 90%, therefore these 5 high R 2 values may be false indicator of linearity resulting from a strong outlier affect. While R 2 values alone cannot be used to determine whether a relationship is best modeled by a linear function, these results indicate that the TD measurement is more linear with respect to time than %LC. It should also be noted that some samples with low potency were noted to have a high degree of fibrillation, leading to samples with a high viscosity. This made the samples difficult to analyze and is not a good measurement of the true chemical degradation and problematic samples were removed from the available training data. In the next section, we explore different machine learning models for predicting these two measurements of chemical degradation.