Our comparison of local lipid oxidation in mono-and polydisperse emulsions pointed to a difference in packing of proteins at the droplet interfaces. We pursued this lead by further investigating the spatial, inter-droplet heterogeneity of lipid oxidation. Red fluorescence of BODIPY 665/676 in WPI-stabilized monodisperse emulsions showed clear inter-droplet heterogeneity in the oxidation of similar-sized droplets as quantified by standard deviations (shadowed areas in Figure ). This heterogeneity in fluorescence intensity levels confirms that for similar-sized WPI-stabilized droplets in a monodisperse emulsion, oxidation levels can differ greatly (Figure ). We attribute this to the aforementioned heterogeneous coverage of droplet interfaces, which prompted us to further investigate the interplay of lipid and protein oxidation at droplet interfaces of WPI-stabilized emulsions with CLSM.