Next, we evaluated the selectivity of the developed sensor for CRP using a sample in which the biomarker was mixed with equimolar amounts of common interferents, including interleukin-6 ( IL-6) , fibrinogen, myoglobin, bovine serum albumin ( BSA) , human serum albumin ( HSA) . As demonstrated in Fig. , CRP ( 100 ng mL -1 ) was specifically detected in the mixed sample, whereas interferents induced negligible signals. The results indicate that the biosensor possesses a high specificity towards CRP conferred by the anti-CRP nanobodies.