Hence, binding energies over clusters of three and four adatoms were similar to the extended surface binding for coronene. In the DFT-optimized monomers, rings one to three consistently remained relatively planar with respect to the underlying adatom-containing Cu substrate while rings four to six demonstrated considerable coiling. For dimers, surface interactions drive structure formation. For example, in one-adatom dimer systems, the sole adatom binds only one of the enantiomers, while the other enantiomer flattens as expected on the basal surface. By contrast, three-adatom systems evolve towards configurations where both molecules bind the reactive defect adatoms. These effects are observed in all systems considered here, regardless of chirality, which is an indication that chiral interactions take a secondary role to the increased surface reactivity.