As an example, we consider the lattice energy of the 1,4-di-adamantyl-cyclooctatetraene DIAD-COT crystal at the HFLD level. This was estimated by computing the energy required to remove the central DIAD-COT molecule from the molecular cluster shown in Fig. , representing a section of the experimentally detected X-ray crystal structure reported by Schümann et al. In Fig. , this lattice energy ( ) is decomposed into physical components such as electronic preparation, electrostatics, exchange and dispersion to the interaction using the LED scheme. This decomposition reveals that the major contribution to the stability of this system originates from dispersion forces. In Fig. , each of these physical components is decomposed into fragment-pairwise contributions using the scheme introduced here to assess the effect of each monomer pair on crystal stability.