The dUCT-v2 enhancement was tested against UCT using the ZINC stock. The number of routes, steps, and several sustainability metrics were taken for comparison. For each step in a route, the solvent, temperature, stoichiometry, element sustainability, atom economy and safety, were assigned scores between 1 and 3 (1 being the most sustainable) based-on the predicted reaction conditions. For every route, the average score across all steps was taken for each metric and summed to a total sustainability score for each route shown in Table . Routes 1 through 4 were found by both UCT and dUCT-v2, route 5^ was found solely by UCT, and routes 6* through 9* were found solely by dUCT-v2. ), likewise for dUCT-v2 in Table . Tables and also show the decrease in computational clocktime achieved by dUCT-v1. eUCT gave more modest time reductions than the other enhancements.