Based on the obtained experimental results, the performance of a continuous cross-flow separation unit for the isolation of nopinone from methanol-water solvent was estimated by considering a series of dead-end batch separation units. The results indicated that significant separation can be attained using the BW30 membrane at reasonable commercial scale, which highlights its potential use as an energy efficient method for the separation of nopinone in continuous flow processes. The presented work provides valuable engineering insight into the system's characteristics which can be leveraged for assessing its suitability across various industrial applications. Finally, the use of this system was explored in a case study process for the green synthesis of paracetamol from β-pinene, where the results were utilised in the modelling of the relevant nopinone separation step, achieving the removal of 64 mol% feed solvent into the permeate stream.