The iterative local minima search algorithm was then applied to reconstruct the 3D structure of the experimentally investigated NPs of Figure It is important to note that in our case, images are recorded sequentially. The recording dwell time per pixel in this ADF STEM experiment is 0.6 µs, and the total recording time required to capture one assigning it to the closest element in terms of SOAP distance (using Equation ( )). Then, in the second step, we assigned the analyzed environment to the cluster to which its closest reference belonged.