A weight-factor transformation has been shown to improve compound identification results for EI-based identification, which has not been investigated for ESI-based identification. Thus, to evaluate the effect of a weight-factor transformation on 1) the processing pipeline used by Li et. al., and 2) the two known and one novel similarity measure(s), we implement a weight-factor transformation at three different stages in the processing pipeline used by Li et. al., as depicted in the flowcharts in Figure (a)-(c). The first processing pipeline initiates with a weight-factor transformation, followed by cleaning and matching, hereafter referred to as WCM. The second pipeline begins with cleaning, followed by a weight-factor transformation and then matching, hereafter referred to as CWM. The final pipeline starts with cleaning, followed by matching, and concludes with a weight-factor transformation, hereafter referred to as CMW.