were equally weighted, putting no emphasis on either domain. In order to improve the force field for both domains, in this work different inter-domain weights are evaluated to rebalance the loss function. For example, by setting m j=1 ω MD j = 1.44 (that herein simplifies to ω MD = 1.44) and n i=1 ω MM i = 0.48, a re-balancing is reached that assigns 75% of the overall weight to the density, and thus is called "75-25". The different intra-domain balancing setups used herein are listed in section 2.4.