Ostwald ripening is the presumed sintering mechanism (expected for clusters considered here), the process produced a 1-atom-fewer and a 1-atom-more clusters in every step. Therefore, the cluster dissociation energy, E D , to place a monomer on the surface is a relevant energetic descriptor. On the other hand, if the particle migration and coalescence mechanism is operative, then cluster adsorption energy with respect to the GM in the gas phase is a descriptor. Therefore, the effect of Ge content on the probability of PtGe nanoclusters to sinter is evaluated using these energetic criteria (Table ). The largest adsorption energies are found for pure Pt 4 and singly-doped Pt 4 Ge clusters. The rest of the PtGe clusters exhibit lower values. Indeed, the larger the Ge concentration the weaker the interaction with the support is, where Pt 4 Ge 4 is predicted to have the worst sintering resistance by particle migration, with a reduction of E ads by ca. 1.3 eV.