The value of KD is similar to previously reported values. This coincidence further supports the specific detection of the CRP and anti-CRP mAb reaction by the devices. The noise floor, defined as three times the standard deviation of S for 0 nM, was calculated to be 4.2 mV. The intersection of the noise floor and mean fitting curve yields the limit of detection (LOD) in the system, which was determined to be 2.9 nM. This value was smaller than the CRP concentration in the plasma of healthy individuals (6.8 nM), suggesting the practical applicability of our devices. The plot also shows a consistent trend regardless of the functionalized regions of the mAb: GFETssig (#1-#24)