Organic cages are discrete molecular systems assembled through covalent bond formation and possessing internal cavities capable of binding guest species. Shape-persistent cages with a permanent accessible cavity are often referred to as porous organic cages (POCs). The ability of POCs to encapsulate guests has led to their use in a variety of applications including catalysis, gas sorption, and molecular separations. Furthermore, the synthetic tunability of organic cages has allowed a wide range of topologies to be realised and for them to be studied as materials in the solid-state, in solution, and as porous liquids. Dynamic covalent chemistry (DCC), such as imine bond formation, is often exploited for the synthesis of POCs due to the 'error correction' inherent to reversible chemical bonds, enabling access to the most thermodynamically favourable structures in high yields. The modularity of DCC also permits facile exchange of related building blocks to modulate the properties of organic cages. In 2011, for example, Cooper and co-workers reported the tuneable porosity of a 'scrambled' mixture of POCs assembled from a trialdehyde and a combination of two diamine building blocks, compared to topologically isostructural POCs formed from just a single diamine, due to increased structural disorder. Later, this group also reported the increased solubility of a similar, structurally analogous scrambled mixture of POCs due to increased structural disorder. While the dynamic nature of imine bonds makes them highly convenient for preparing POCs, they can be hydrolytically unstable, although there are exceptions, limiting the utility of the cages. To overcome this, imines can be 'fixed' by reduction to amines, providing a level of kinetic robustness, although sometimes at the expense of their permanent porosity due to structural collapse resulting from increased flexibility. 'Fixing' can also allow post-synthetic modification (PSM) of the cage scaffolds, to both modify their properties and install functional units, that might otherwise be incompatible with dynamic covalent bonds.