The overall technique implemented was continuous, single-batch titration on individual samples. Subsequently, we organised the computer numerical control (CNC) movement scheme for relative translation between samples and sensing/actuating elements. Individual samples of up to 15 mL were contained within jars that were organised into arrays conforming to MTP-format dimensions using custom 3D-printed holders. In the interest of compactness, we aggregated sensing and actuating elements into a single probe head that would concurrently perform liquid dispensing, pH measurement and homogenisation, as required by the experiment. Since translating and immersing the probe head between samples is a low agility-high accuracy (LA-HA) action, a Cartesian movement platform, as opposed to an articulated robot arm, was the obvious choice for achieving effective movement, while saving cost and time in implementation . To maximise travel, a hybrid movement platform was used: the probe head translates in X-Z and the sample holding stage translates in Y. Here, the high viscosity of the analyte played to our advantage since samples could be moved quickly without spilling.