Given the potential use of isobutanol as a biofuel, these rates can be integrated into detailed kinetic mechanisms to help improve the accuracy of combustion models at a range of combustion temperatures (500-700 K). Refining the oxidation chemistry of key products predicted in this work, such as alkenols and larger aldehydes, might help improve accuracy of detailed models still further. Due to the potential for multireference characteristics, important reactions in this work (such as βAlkoxyIsom, β-βscissionFromAlkoxy, and β-γHO2elimFromRO2) could be better constrained using multireference calculations. Further, an improved understanding of low-temperature isobutanol oxidation may require the inclusion of the O 2 reactions with stabilized QOOH radicals, such as γQOOHα.