The database of metal-based approved drugs (MetAP DB) was assembled from a literature search (peer-reviewed literature), plus searching the DrugBank portal, V. 2024. Three additional criteria were used for the final selection of compounds used to construct the database. The first filter was that the identified compounds were previously approved for clinical use by the Food and Drug Administration (FDA) of the USA as "metallodrug," "imagenology metallodrug," "radioimagenology metallodrug," "radiotherapy metallodrug" or "photodynamic metallodrug."