Below, I present the top 10% of the four combined hit lists to discuss representative examples and highlight notable trends. The two tables below show the combined hit lists generated by the Vinardo and dkoes scoring functions without the heme cofactor. Notably, the Vinardo scoring function yields 8ABX and 6AZV targets at a high frequency among the top-ranked solutions, whereas the dkoes scoring function produces more diverse results and does not include 8ABX or 6AZV at all. This indicates that, although both scoring functions performed very well in self-docking tests, they apply different weights to energy terms and interaction types. Neither scoring function is bad, nor is either one perfect, and the qualitative differences among their top hits justify the use of at least two distinct high-quality scoring functions-preserving both sets of results for more precise refinement calculations in the future.