Dynamic Light Scattering kinetics of COF-300 nanoparticles: DLS experiments were carried out using a VASCO KIN Particle Size Analyzer from Cordouan Technologies to determine the evolution of the hydrodynamic diameter over time. Measurements were collected for 60 seconds during 48 hours after mixing. The Cumulant analysis was applied to extract the hydrodynamic diameter by means of the Stokes-Einstein equation. Micellar solutions of TAM and BDA monomers were prepared in a CTAB/SDS (96:4) mixture in water. DLS kinetic experiments were performed by merging 1 mL of the TAM containing micellar solution, and 1 mL of the BDA containing micellar solution. The final concentration of DLS sample was composed of 0.094 м CTAB surfactant, 0.0039 м SDS surfactant, 0.3 м acetic acid, 0.0017 м TAM precursor and 0.0034 м BDA precursor.