To verify the stability of the MOFs and free up the pore space within the open anionic Zr(IV)-ellagate frameworks, ion exchange experiments were carried out to replace the cationic OSDAs with smaller monovalent metal cations such as Na⁺ and K⁺. Ion exchange was performed for 24 h at room temperature in aqueous salt solutions. All MOFs indicated stability as confirmed by PXRD, with the exception of SU-112 which underwent amorphization (Supplementary Fig. ). The PXRD patterns of SU-107 after Na + and K + ion exchange exhibited large peak shifts indicating significant structural changes likely due to framework dynamics.