In reviewing the literature to prepare the article, we found that the terminology in this area is somewhat confusing. For example, different terms such as lipid vesicles and liposomes refer to the same molecular architecture in different contexts. For example, in an article published by Akbarzadeh et al , liposomes are described as "small artificial vesicles of spherical shape that can be made from natural, non-toxic phospholipids." This description agrees very well with the description of lipid vesicles, which are described as "highly ordered assemblies consisting of one or more concentric bilayers formed by self-assembly of amphiphilic building blocks in the presence of water." It is very striking that these two descriptions, although worded differently, allude to self-assemblies of amphiphilic phospholipids with one or more layers. For no apparent reason, these two terms are used interchangeably to some extent in the literature, including this article. Interestingly, this is also true for the terms CSHNs (vide supra) and LPN or LPH, which stands for "lipid-polymer hybrid nanoparticles" (vide infra).