In this work, the restricted parent docking-cavity, to generate a large list of children possibilities improving the DW docking-score, molecular weight and hydrophobicity, helped the generation of many alternative leads to the first one identified before with sS and selection among the vast wide chemical space, otherwise impossible to reach by any other methods. Filtering by non-toxicity, and docking to ADV, a different program with wider grid-dependence and LELP normalized, helped to develop a consecutive consensus among the DW+ADV+LELP results to generate a top-lead downsized list with presumably higher accuracies than before. The top-lead list may suggest a possible chemical synthesis for validation through experimental work.