the Ru-support charge transfer, which is indicated by the red line, and the contribution from restructuring effects (structural contribution) is not possible. Furthermore, these structural contributions are an important, but not the only effect that can result in a sizable deviation of a data point from the linear correlation indicated by the red line. This is illustrated, e.g., by the O-vacancy formation on the 2i site, where the structural contribution is very small (see Table ). These questions will be investigated in more detail in future work. Nevertheless, despite these deviations, the energy required for O-vacancy formation depends mainly on the feasibility of charge transfer from the support to the Ru nanorod upon vacancy formation, and this in turn depends mainly on the distance between O-vacancy and the closest Ru atom.