The threshold oxygen concentration at which autoxidation begins to dominate is not well understood for many fouling monomers, let alone for mixtures. Fouling in an industrial distillation column is a much more complicated phenomenon. The interplay between the detailed chemistry of the dissolved oxygen and the complex mixture of species in feedstock, the wide range of tray temperatures (which affects the kinetics), the convective flow, the vaporliquid mass transfer, and the phase equilibria in industrial units are not well-understood.