The observed multiplicities and splittings are a function of the chemical and magnetic environment of the resonating 1 H nuclei, both within the analyte molecule and the solvent/solutes surrounding it. Therefore, multiplicity is a highly characteristic property of chemical structure. The plethora of structural information encoded within multiplets has both advantages and challenges: while higher degrees of signal multiplicity encode additional valuable structural information, the multiplets and NMR spectra as a whole do not have straightforward connections with structural motifs; unlike in IR and UV spectroscopy, NMR spectra are collections of rather unique patterns that tend to change in response to apparently subtle changes in the molecular structure and/or sample environment. Recent work indicates that patterns can be attributed to molecular classes in an automated manner .