The acetylene derivative 4ʹ-(3-ethynylphenyl)-2,2ʹ:6ʹ,2ʺ-terpyridine (H-C2PhTpy) (Fig. ), which contains a terpyridine unit that can coordinate with transition metal ions, was synthesized in the following three steps. The details of the organic synthesis are provided in the Supporting Information. First, the terpyridine framework (-PhTpy) was formed via Kröhnke pyridine synthesis using 3-bromobenzaldehyde, 2-acetylpyridine, and ammonia (Fig. ). Next, the Sonogashira coupling reaction was used to introduce a trimethylsilylethynyl group at the 3-position of the phenylene ring (Fig. ). Finally, the trimethylsilyl protecting group was removed using fluoride ions, yielding the white target compound H-C2PhTpy (Fig. ), with a final yield of 13%.