Theoretically, as discussed previously, the dynamics of release from liposomes (or vesicles) is thought to be mainly controlled by the product of diffusional flux and the pore area. In contrast to exocytosis where pore opening and closing is driven by the cell, the liposome pore cannot close under a constant strong electric field. Thus, the outflow flux should fit to a SigExp decay following the diffusion model of Cottrell. But if a rate-limiting desorption process is added before release through the pore, the entire release rate becomes a combination of desorption rate and diffusion (via pore) rate, and both can be fit to SigExp decay with different scaling factors.