Single wall carbon nanotubes (SWCNTs) are one-dimensional nanomaterials and can be considered as rolled-up graphene sheets. The roll-up direction is described by the chirality (n,m) and determines their properties . SWCNTs of certain (n,m) chiralities are semiconductors and fluoresce in the near infrared (NIR), which falls into the tissue transparency window and provides less scattering and background signals . The fluorescence of SWCNTs does not bleach but is highly sensitive to changes in their local environment . These unique properties make SWCNTs ideal building blocks for biomedical sensors and various applications in this field have already been demonstrated . Biomolecules such as the important neurotransmitters dopamine or serotonin , riboflavin (vitamin B2) , small metabolites for pathogen identification , stress indicators like H2O2 or even peptides and proteins can be detected by SWCNT-based biosensors. Most of these sensors are designed by non-covalent surface chemistry with various kinds of polymers such as single-stranded DNA (ssDNA) or polyethylene glycols that create a corona phase around the SWCNT . This organic corona phase determines selectivity and sensitivity of the sensor because it controls both molecular recognition as well as fluorescence changes . Additionally, factors such as ion and surface accessibility or porosity have been shown to be important .