A recent study has focused on developing novel therapies that might be effective not only for COVID-19 but also for other viruses including monkeypox and others. mRNA Moreover, a universal vaccine is also required for the influenza virus as it might overcome the challenges of several different viral strains by targeting the functionally conserved areas of the different strains of the virus with antibodies for broader protection. A major challenge in it is that such kinds of antibodies are mostly silent immunologically which means that they are immune-recessive. Therefore, researchers are focusing on the reasons for ignorance of these antibodies by the immune system so that they might be more visible to our immune system. For instance, structure-based immunogen design techniques have been utilized for redirecting the responses of the immune system towards those silent but significant vaccine targets and to develop universal vaccines for various strains of influenza virus .