It can be concluded that solvent encoded spectroscopy using reduced sample length of 1.8 and 1.3 cm samples not only reduce the deuterated solvent D2O requirement by a factor of two to three using a standard 5 mm o.d. NMR tube but also improve S:N of heteronuclei by more than two-fold. This improved sensitivity allows faster data collection which reduces spectrometer utilization cost. For 13 C and 15 N two to threefold higher S:N was observed which can provide four to an eightfold reduction in precious spectrometer time. Even more significantly routinely employed NMR experiments were used for such hetero-nuclei to get enhanced S:N using a straightforward sample preparation procedure avoiding the need for costly NMR tube or difficulty in shimming. The shimming procedure was straightforward using SEN 1.8 and 1.3 cm as in the standard sample.