4-Bromo ring-substituted ethyl phenylcyanoacrylate (PCA) is reported in vitro, molecular docking, and ADME study of uracil derivatives as potential anticancer agents ; in synthesis of novel selenophenes from activated acetylenes, such as ethyl 2-cyano-3-arylacrylate and potassium selenocyanate ; in Knoevenagel condensation in the presence of polyoxomolybdates as efficient catalysts ; in preparation of highly loaded MWCNT-polyamine hybrids and their application in catalysis ; in catalysis studies on precise control of the oriented layered double hydroxide nanosheets growth on graphene oxides leading to efficient catalysts for cascade reactions , and in synthesis of arylidene derivatives by microwave assisted NH4OAc catalyzed under solvent free condition . 4-Chloro ring-substituted 1,1-dimethylethyl PCA is mentioned in mechanistic studies of copper-catalyzed 1,4-addition of organoboronates to alkylidene cyanoacetates , and in synthesis of β-(arylmethylene)-α-cyano-2-alkenoic acid ethyl ester derivatives via Knoevenagel condensation of aryl aldehydes with cyanoacetic acid methyl ester and subsequent transesterification . 4-Chloro ring-substituted ethyl PCA is involved in synthesis of cyclohepta[b]thiophene derivative incorporating pyrimidine, pyridine, and chromene moiety as potential antimicrobial agents targeting DNA gyrase ; in synthesis of new pyridine, chromene and thiazole containing compounds as antimicrobial and antioxidant agents ; in synthesis, molecular docking and anticancer activity of some 5-aryl-5,10-dihydropyrido dipyrimidine-2,4,6,8tetraone derivatives and pyrido pyrimidines ; in antibacterial and anticancer profiling of new benzocaine derivatives ; in design, synthesis, cytotoxic screening and molecular docking studies of novel hybrid thiosemicarbazone derivatives as anticancer agents . 4-Fluoro ring-substituted t-butyl PCA is mentioned in studies of compartmentalization of incompatible polymers within metal-organic frameworks towards homogenization of heterogeneous hybrid catalysts for tandem reactions ,