The overall penalty for steric interactions (𝑉 #? ) varies depending on the configuration of the ovoids. Therefore, the rotations of the ovoids around P-Cl* axis, which are corresponding to the rotations of substituents, were considered as shown in Figure . The rotation angles of all ovoids 𝒒 "# = (𝑞 A , 𝑞 B , … , 𝑞 K ) were optimized so that the overall penalty (𝑉 #? ) is minimized. The detailed algorithm for optimization and workflow of microiteration is described in Figure .