IPR014735 is a transposase Tn5-like and N-terminal. The N-terminus of Tn5-type transposase proteins houses this domain. The prokaryotic Tn5 transposase generates two types of DNA contacts: trans contacts for catalysis and cis contacts for DNA recognition. Additionally, it establishes protein-protein contacts. During catalysis, Tn5 transposase uses two cations in its active site. These cations change the shape of DNA that is bound to them and are necessary for transposition. The α/β/α fold of Tn5 transposase is of the RnaseH type. The N-terminal domain forms an orthogonal T-tract structure.