The AutoDockVina (ADV) dockings were performed in Python vs3.8 included in the PyRx098/PyRx1.0 package as described before A 45x45x45 Å grid automatically centered into the target protein surrounding the FtsZ molecule to explore ADV docking-cavity alternatives was chosen, in contrast to DW docking to the PC190723-defined binding cavity. ADV generates rotatable conformers from input ligands and selects the lower dockingscores during iterations . The conformer predicting the lowest binding-score is selected for output expressing its binding potency as apparent Kcal/mol. Experimental accuracies of ± 2.8 Kcal/mol 59 are predicted for ADV while repetition of ADV docking to the same protein target were < 10 % of dockingscores (n=3-10).