During the past 10 years since the publication of our original review article , the field of quantum-chemical embedding methods in general and of sDFT/FDE in particular has seen a tremendous evolution and diversification, up to the point that there is almost a continuous range of methods from QM/continuum and QM/MM methods up to QM/QM methods. Some of these methods may be regarded as simplified versions of sDFT/FDE, in which certain contributions of the interaction terms are either approximated (e.g., electrostatics in terms of distributed multipoles and polarizabilities) or entirely neglected (e.g., non-classical terms).