Our research began with a focus on addressing the challenging task of introducing the elusive NCF3 fragment. This relatively unexplored moiety has recently garnered attention from the medicinal chemistry community as a valuable scaffold for modulating pharmacokinetic properties such as lipophilicity and amine basicity. Despite its potential, the widespread adoption of this fragment has been hindered by the limited availability of methodologies available for its installation, especially the lack of methods for the direct incorporation of trifluoromethyl nitrogen fragments. In most cases, existing methodologies rely on the trifluoromethylation of amines, requiring the stoichiometric use of silver salts or reagents with low atom economy. This limitation underscores the need for novel and more efficient approaches to overcome the challenges associated with introducing the NCF3 motif.