Next, the impact of bases and solvents was evaluated to provide further insights and improvements on this reaction (Table ). Remarkably, varying the bases from organic bases to inorganic ones suggested sodium hydride to be optimal (Table , entries 1-5). In terms of the solvent, THF gave better results than other solvents, such as DMSO, DMF, toluene, 1,4-dioxane, and MeCN (for more details, see Supporting Information, Table ).