Only one manuscript shared primary data in a format recognised as a formal standard in chemistry, and although others had some elements of metadata that could be extracted, the proprietary nature of the other formats mean they are not interoperable and reusable. Only two primary data packages contained information to direct a user to the original manuscript once those data had been downloaded; and none had an associated data DOI or link to the manuscript DOI. Metadata, typically embedded in SI associated with the manuscript on a publisher site, is lost.