A common challenge with integrating highly specialized hardware (either legacy devices that already exist in a laboratory, or even newly procured hardware) can be the lack of readily available or well-documented software interfaces, APIs, or SDKs for controlling this hardware. While we could circumvent this problem for all the synthesis hardware components described above by carefully selecting the most appropriate hardware models and vendors according to the provided hardware and software specifications, we could not find a combined DLS and Zeta measurement device at the time of building our SDL for which the hardware specifications met all our needs, i.e., the precise and flexible characterization of nano-and advanced materials with a high dynamic measurement range while at the same time offering programmatic interfaces that gave full control over data acquisition parameters and allowed remote control of the hardware.