In 2023, Tian et al. published a pioneering review in which they attempt to cover the usefulness of each analytical method, trying to propose an optimal set for characterizing polymer aging as a function of polymer properties and degradation stage. The numerous analytical methods are discussed using two main characteristic types: a macro approach focusing on polymer properties, and a molecular approach focusing on degradation products. However, this review remains theoretical, based solely on the results of other publications, and is very general because it applies to the wide range of polymers described in the literature. As a result, the authors do not propose any concrete application cases, enabling the panel of analytical methods to be effectively compared under uniform conditions. Thus, in order to put these initial conclusions into practice, and to offer a concrete case study, our work proposes a deeper focus on PBPAC, and concentrates on the definition of an optimal strategy to study its degradation through a molecular approach, selecting, as in the aforementioned review, the ideal panel of analytical methods for each level of degradation. The strategy implemented is based on five of those commonly used for PBPAC degradation studies: SEC, an indispensable analytical tool for measuring the evolution of the molecular weight distribution (MWD), providing an overall understanding of the evolution of chain length distribution as a function of the extent of conversion. HPLC, which enables the identification of small mass products. FT-IR (Fourier-transform infrared spectroscopy) and NMR (Nuclear magnetic resonance) are used to identify chemical groups modified during depolymerization. Finally, MALDI-TOF (Matrix Assisted Laser Desorption Ionization -Time of Flight), to characterize end-of-chain (called end groups) modifications. This study is the first to our knowledge to compare these five analytical methods applied to the depolymerization of PBPAC, or even any type of polymer. The outputs provided by each analysis method are discussed, along with their respective sensitivities and range of effectiveness, and finally the problems associated with each. In order to cover the various stages of PBPAC depolymerization, methanolysis was here used as a degradation method, based on the work of Bhogle et al., allowing both rapid total and slower very partial degradation. This makes it an ideal model approach for covering all the levels of degradation encountered by both the biological catalysis community (with low to very low levels), and the chemical catalysis community (with generally much higher levels). Finally, we hope this study will serve as a common base for the scientific community in the study of PBPAC depolymerization, helping in the choice of methods according degradation method selected.