, from M. aeruginosa PCC 9432. In line with these observations, the updated genome data for the oscillaginin-producing P. prolifica NIVA-CYA 98 (NCBI: AVFZ00000000) includes a longer contig harboring the mic BGC, extending its 5' region which features additional genes encoding a FAAL, ACP, a dimetal-carboxylate halogenase and a SAM-dependent methyltransferase (Fig. ). Despite these bioinformatics-based data, direct biochemical evidence connecting microginins with their putative BGC (mic) is lacking.