However, the advent of nano hydrogel nanozyme and OC (Organic-compound-based, mostly for agricultural and eco-friendly) nanozyme partially resolve these limitations: These nanozymes do not rely on inorganic nanostructures or catalysts but contain iron-ion-based ligands as active sites generated simultaneously with nanoparticle formation. And the portion of iron ions in these nanozymes is within an acceptable atomic ratio. Particularly, previous OC nanozymes offer a complete one-pot, partially cofactor-mimetic, homogenous nanozyme without any chemical engineering process, heat treatment, or ionic gelation, which contributes to higher particle generation yield . However, the range of organic materials used to create agricultural and food applicable, sustainable OC nanozyme is still limited. Thus, expanding the option of constituent materials to develop those 'sustainable', organic-compound-based nanozyme is desired to increase their diversity .