Molecular photoswitches have conquered virtually every applied chemistry field allowing to change the state of nanoscopic systems with high precision by simple light irradiation. 1,2 They are indispensable to instill spatially and temporally resolved outside control over different scales of animate and inanimate matter from molecular to supramolecular and finally to macroscopic sizes. As the field of photoswitch research progressed a large portion of work has been aimed at developing thermally stable and red-or near infrared (NIR)-light responsive variants in the last decade and this research continues to be a hot topic to date. Bistable red/NIR-light responsiveness is crucial for many application areas that do not tolerate higher energy UV or visible light, especially in materials research, chemical biology, photopharmacology, and catalysis. Further, such red-shifted photoswitches can be combined with different photoresponsive components, e.g. other photoswitches, 26 fluorophores, or photocatalysts that need to be addressed individually. To elicit red-light responsiveness direct excitation is highly desirable but also sensitization or two-photon processes can be efficient to realize red-light responsiveness. So far however, red/NIRlight responsive photoswitches still require higher energy UV or visible light for the reverse switching direction. The only notable exception is the recently published supramolecular induction of all-red-light photoswitching in indirubin, which served as a first proof-ofconcept study but could not deliver a substantial isomer accumulation for the longer wavelength red-light induced process. Thus, the question remains how far into the red part of the electromagnetic spectrum can photoswitching be pushed and how can a truly efficient allred-light responsive photoswitch be generated.