Some of the limitations of the top-children predictions described here are: a) Crystallographic 3D-models contained prefusion-stabilizing mutations and excluded p27 sequences (both of which may interfere with docking), b) only single mutations could be studied, due to the limited number of mutants coding for several mutations each , and c) the high-docking affinity selection criteria has not yet known in vitro / in vivo fusion inhibition properties. Nevertheles, the topchildren identified here may be employed for in vitro experimental evaluations.