While nanomotor propulsion and navigation methods have been significantly advanced with two decades of research, better adaptability and biocompatibility are still required for the application of nanorobots. Particularly in the biomedical field, long-term performance is crucial in a complex physiological environment with its associated high ionic strength, high viscosity, and potential plasma protein biofouling. Surface coating has been extensively used to encode multiple functions and regulate propulsion efficiency for nanomotors . Nevertheless, optimizing the material composition to balance all requirements for biomedical needs , while realizing multiple functions and keeping the composition simple for scalability, remains an unfinished task .