Thus, with the possible existence of nucleotides, nucleic acids, peptides, and amino acids on early Earth, let us thus examine some examples of coacervates that can form from these biomolecules. An example of a peptide-peptide coacervate is composed of poly-lysine and poly-glutamate. Peptidepolynucleotides and mononucleotides can also form coacervates due partially to the interaction between cationic peptide residues and the anionic nucleic acid backbone or phosphate moiety. For example, poly-L-lysine can coacervate with nucleotide monomers such as ATP or with nucleic acid oligomers such as RNA. Monomers with fewer phosphate groups/negative charges, such as AMP, have even been shown to coacervate, in this case upon binding with oligoarginine. As this demonstration shows, peptide-nucleic acid coacervates are not limited to poly-L-lysine, as other peptides including oligoarginine have shown coacervation ability upon binding with nucleic acids as well. In addition, droplets with increased structural complexity, such as multiphase droplets, may also form as a result of coacervation between two or more components such as certain cationic polypeptides and nucleotides or nucleic acids (both RNA or single-stranded DNA). Higher order structures, such as liquid crystals, may also coassemble with coacervates upon reaching the proper conditions, i.e., binding of peptides with high concentrations of liquid crystal-forming DNA duplexes. Additionally, other than peptides, other types of primitive positively charged polymers or molecules could have also formed coacervates upon binding with nucleic acids or nucleotides. For example, one class of polycation that is of interest are polyamines, which are polymers containing multiple amino groups that have the capacity to be positively charged, and have been shown to condense certain nucleic acids in biology. In particular, putrescine, a simple polyamine with four carbon atoms and two terminal amines (two potential positive charges) has been synthesized under prebiotically plausible conditions. Putrescine is a biochemical precursor of more complex polyamines, such as spermidine (three amines) and spermine (four amines), but to date, no prebiotically plausible syntheses of either has been demonstrated, although it is proposed that any prebiotic syntheses of spermidine or spermine would likely require putrescine as a reactant or intermediate. As short polyamine-nucleic acid coacervation has been demonstrated, such as spermine/spermidine-RNA coacervates, assuming spermine or spermidine could have been synthesized at some point during the origins of life, such coacervates could have existed on early Earth. Furthermore, at some point if longer polyamines could also be synthesized, longer polyamine-based coacervates could have provided even further function, such as up-concentration of analytes in polyamine-nucleotide coacervates or increasing catalytic ribozyme reaction rates within polyamine-anionic peptide coacervates, to a primitive system.