Theoretical studies and experimental analyses studied the optimal structure of the RNT hierarchy. Further AA MD studies using OPLS 2005 FF showed the entropically driven self assembly of RNTs in water. However, due to the limitations of experiments, the 3dimensional reference interaction site model (3D-RISM), and AA MD simulations, the development of a coarse-grained model of RNTs will provide the ability to explore larger scale and longer time MD phenomena. The utilization of the MARTINI FF will create the foundation for future CG MD studies of RNTs interacting with lipids, proteins, DNA, RNA and other small molecules. A mechanistic understanding of RNT systems could be achieved by an accurate CG model of the RNT and subsequent RNT systems. These CG simulations can provide more details of the phenomena that may be computationally expensive and experimentally difficult to obtain from AA MD simulations, 3D-RISM theory, and experiments.