LC domains uniquely contain only a few amino acids (AAs) among the 20 canonical AAs; in contrast, other domains/proteins contain most or all of the 20 AAs. Thus, to understand the biochemistry of membraneless organelles it is important to investigate the sequence to phase behavior relationship of IDPs. Here, we investigate the significance of how valency/AA sequence impacts/initiates phase behavior of organelles in the context of a "sticker and spacer" model.