To generate the fingerprint-based chemical space visualization (see Figure .2), the file obtained from the previous workflow must be read by the For BIOFACQUIM, the fingerprint-based chemical space was customized to display the biological kingdoms of origin for the compounds using distinct colors. From the BIOFACQUIM´s fingerprints (MACCS keys) based chemical space visualization (Figure ), it was determined that plant-derived compounds occupy most of the chemical space, while some compounds derived from fungi overlap with certain plant-derived natural products, indicating a high similarity based on the selected fingerprints. The smallest group of compounds (those originating from marine animals) occupies a small region of the chemical space.