DNA nanotechnology holds the promise of catalyzing a revolutionary shift in the realm of molecular machinery and motors. In addition to switchable nanodevices between two equilibrium states upon actuation, it is feasible to design advanced nanomachines that use external energy, such as a catalytic induce, to move away from equilibrium and shift continuously between various mechanical states. By regulating the amount of energy absorption and encouraging the desired transition, work, and change in the environment become possible , . To achieve this goal, DNA-based materials must be integrated with other simple nanodevices to create well-run nanomachines , such as biological motor enzymes in bio-hybrid DNA rotor-stator nanoengines or motor proteins in novel nanomotors constructed through DNA origami. These nanomotors are capable of continuously converting chemical fuel into mechanical motion, linearly, and can be tuned, with speeds measured in nanometers per second, and they can travel distances of several microns .