We have therefore seeked for other types of reactions which allow for B-C bond formation. The Suzuki-Miyaura coupling (SMC) of boron-substituted carbons with halogen-substituted carbons is well established, and available boronic acids are abundant. Bearing in mind the very narrow path which led us to successfully use the Buchwald-Hartwig coupling (BHC) to amines and amides, we tested a great number of conditions (base, solvent, heating system, ligand) for reacting 4methoxyphenylboronic acid with [B12H11I] 2-(details of this can be found in the SI). We looked for the desired formation of a B-C bond, the side reaction to [B12H12] 2-resulting from hydrodehalogenation, and the amount of starting material which was left unreacted (see SI). The conditions and yields for the optimized reaction are found in Table . As found for the B-N bond formation, DavePhos turned out to be the best Pd ligand (Figure ). This is not surprising, as the first steps of BHC and SMC are identical. Other ligands (such as XPhos) performed worse, or were not even effective in reacting the starting [B12H11I] 2-. KOH turned out to be the best base for SMC, whereas BHC proceeded best with tBuOK. DavePhos G4 did not promote the SMC, in contrast to DavePhos; it left much of the starting boronic acid unreacted and promoted hydrodehalogenation to [B12H12] 2-. For BHC with [B12H11I] 2-, we had found that 10 mol% Pd and 20 mol% DavePhos were needed for efficient conversion. With the SMC described here with the same [B12H11I] 2-substrate, we could lower the amount of Pd2(dba)3 to 2.5 mol% and get complete conversion with a reaction time of 3 h.