Inflimination dementia are correlate . Cyclooxygenase-2 (C0X-2) is an enzyme that plays a key role in promoting inflammation. In contrast, when cyclooxygenase-2 activity is blocked, it results in reduction of inflammation. Cox-2 becomes active only at the site of inflammation i.e peripheral tissues. These are propitious curative molecules not only for the treatment of inflammation, evidence of higher level of inflammation when compared with those of people without dementia, On the basis of scientific result alpha eudesmol & terpinen-4-ol blocked Cox-2 activity.