Although silver-based REs are widely used for various battery chemistries , their reliability needs to be further improved for microelectrode setups. During the experiment, we observed unstable potentials after 18 hours, which we believe to be induced by changes of the liquid-junction potential related to the RE filling solution being contaminated by electrolyte diffusion through the frit . Lithiumgold REs showed satisfactory performance with potential drifts within ± 50 mV, however, the constant drift over time limits its usage for long-term experimentation. This behavior can be explained by the slow self-discharge of lithium-based alloys . We find that lithium REs have almost negligible drift, which makes them the most appropriate for the electrochemical measurements of large battery materials libraries using a scanning droplet cell (Figure ). The reproducible behavior of the lithium REs was confirmed during another identical series of experiments over 132 hours (Figure ). Nevertheless, we would recommend performing the calibration of RE potential using a redox couple with a known potential before and after each experiment run. Despite the selection of the proper RE being crucial for the reproducible measurements, the cell geometry, electrode area and position might also play a significant role in electrochemical potential drift , so further research and modelling of electrochemical response for SDC would be needed.