Operando DRIFTS-MS experiments of temperature programmed oxidative dehydrogenation of 2-propanol were carried out using a heatable continuous flow DRIFTS cell with a calcium fluoride window from PIKE Technologies. The exhaust of the cell was connected to the MS device used for catalytic testing as well. The samples were oxidatively pretreated in a flow of 20 vol% O2 in Ar totalling to a flow of 25 mL•min -1 . 2-propanol adsorption experiments were carried out exposing the sample to a flow of 21.73 mL•min -1 8.0 vol% 2-propanol in Ar at room temperature. Then, O2 co-dosing was started resulting in a total flow of 22.73 mL•min -1 7.6 vol% 2-propanol and 3.9 vol% O2 in Ar for a 2-propanol:O2 ratio of 2:1 and 7.4 vol% 2propanol and 7.5 vol% O2 f or a 2-propanol:O2 ratio of 1:1. During 2-propanol adsorption and consecutive O2 co-dosing spectra were recorded every 30 s. Before starting the temperature programmed reaction, the temperature was raised to and kept at 50 °C until constant MS signals were observed. Then the temperature was raised to 400 °C for 30 min at a heating rate of 3 °C•min -1 . Spectra were recorded before and after the pretreatment, once a minute during the adsorption experiments, under reactive gas atmosphere before starting the reaction, every 5 °C during the temperature programmed reaction, at 15 min and at the end of the 400 °C plateau. Spectra were taken from 900 to 4000 cm -1 with a resolution of 4 cm -1 and a scan number of 64 scans.