We want to illustrate here briefly this approach on the MP database on two specific examples, tied to past work in our group. In the first case, we want to use topological search to identify materials with mechanical pliancy and negative linear compressibility, similar to the family of metal-organic frameworks MIL-53, which have a distinctive "wine-rack type" framework. This framework has a net of topology rna or bpq, depending on the type of To confirm the potential of these structures for highly anisotropic mechanical properties, we performed DFT calculations on three matching structures, mp-23768 (ZnAlH 4 O 2 F 5 ), mp-24142 (MgAlH 4 O 2 F 5 ) and mp-725680 (NaPOF 6 ), in order to calculated the secondorder elastic tensors of these materials and therefore, their elastic mechanical properties.