To address these challenges, ultraviolet photodissociation (UVPD) and electron-induced dissociation (ExD), also referenced as electron induced dissociation (EID) or electron activated dissociation (EAD), have been described as complementary fragmentation techniques . UVPD, which uses high-energy photons at different wavelengths (e.g. 213, 266 nm) and EAD electrons with different kinetic energies (0.1 to 25 eV) can offer alternative fragmentation pathways and informative spectra. The benefits of UVPD and ExD have been largely reported in proteomics but only to a limited extent to low-molecular compounds. C. Panse et al. show the benefits of UVPD at 213 nm with complementary fragments for organic micro-pollutants compared to HCD.