While the second model was only modestly better than the first in terms of regression statistics (R 2 , test R 2 , etc.), it was significantly more interpretable. Both the "hardness" term (DEFMO) and alcohol classifier term were conserved across both models. However, the relatively opaque NBOipso value and the ortho-substituent classifier were replaced by two intriguing steric parameters presented above. These were particularly interesting because of their contrasting correlation to CD signal. While steric bulk was positively correlated to CD signal at 2.0 Å, it was negatively correlated at 8.5 Å. As discussed below, these pronounced distance-resolved effects provided insight into subtle intramolecular NCIs within assemblies 12 that critically effect CD signal intensity.