for the reaction from n-hexane, 2-methyl pentane and 3-methyl pentane to cyclohexane at different palladium catalysts. The results in combination with the measured fractions of cyclohexane are shown in Fig. differences between the chemical hardnesses of the catalyst and reactant molecules. In agreement with previous conclusions, this shows that the chemical hardness is of minor importance for the obtained fraction of catalyzed cyclohexane. In contrast, the highest fractions for Pd also agrees with the smallest electronegativity difference to the product and reactant molecules. Corresponding conclusions can also be drawn for the lower fractions and the larger electronegativity differences for the further catalysts. In consequence, one can conclude that similar electronegativities for the catalysts, the product and the reactant molecules in accordance with ∆∆E = 0 for Eqn. ( ) correspond to similar adsorption and desorption energies. Hence, these findings underscore our previous results and assumptions such that nearly identical adsorption and desorption energies point to optimal catalysts with high yield values with regard to the Sabatier principle.