Schiff bases have emerged as promising candidates for cost-efficient hydrogen evolution catalysts. The novel catalyst N, N'-bis(2-hydroxy-1-naphthaldehyde)-o-phenylenediamine ([naph]2-o-ph) demonstrates high capability in generating hydrogen, offering valuable insights for potential applications in water electrolysis . This organic Schiff base system features a distinctive mechanism for hydrogen evolution, involving protonation and electron exchange, which has the potential to reduce costs compared to traditional metal-based catalysts. Notably, while Schiff bases demonstrate efficacy in hydrogen evolution, they have also been successfully applied in other catalytic processes. For instance, Zr(IV)-salphen-MCM-41, a heterogeneous catalyst prepared by immobilizing a zirconium(IV) Schiff base complex onto MCM-41, has shown excellent performance in the reduction and cyclization of ethyl levulinate to γ-valerolactone, with yields up to 90% . This versatility in catalytic applications has the potential to offset development costs and enhance the overall cost-efficiency of Schiff base catalysts.Schiff bases present a promising avenue for developing cost-efficient hydrogen evolution catalysts. Their organic nature, unique mechanisms, and versatility in various catalytic applications render them attractive alternatives to traditional metal-based catalysts. However, further research is necessary to comprehensively assess their long-term stability, scalability, and overall economic viability in industrial hydrogen production processes.