The pyridine groups generate a chiral environment (propeller-type) around the metal centers (Figure , S4-S5). Two axial positions are occupied by water molecules. These water molecules are bent in opposite directions with the enantiomeric crystals. Analysis of the enantiomeric crystal structures suggests CH … O interactions (2.6 Å-2.7 Å) between the metal-coordinated oxygen atoms and the pyridyl ortho-CH groups (Figure ). All six metal nodes in a unit cell have the same chirality, and the unit cell parameters of the structures are nearly identical. For CCDC 2086692, four Cu-N bonds are within the range of 2.001-2.006 Å, and the two axial Cu-O bonds exhibit an elongated bond length of 2.877 Å. The AdDB ligand in the framework has four sets of vertex-center-vertex angles, one of 117.1 °, one of 114.7°, two of 112.2°, and two of 100.7°, whereas the crystal structure of only AdDB shows two sets of angles, four of 113.6° and two of 101.6°. This distortion of the tetrahedral geometry most likely results from the formed chiral crystal structure.