The domain of π-conjugated polymer semiconductors is of keen interest to both the materials informatics and organic electronics communities due to the promising opportunities this class of materials offers for large-area, printable, deformable electronic devices and energy applications. In the years since the advent of the Materials Genome Initiative in 2011, conjugated polymer semiconductors have been associated with over 5,000 peer-reviewed articles (Web of Science, March 2023). A subset of this body of literature has striven to further accelerate knowledge discovery in this materials space through applied data science, machine learning, and high-throughput experimentation techniques. For example, data-driven techniques have recently been leveraged to pursue targeted advances for thin-film device applications including organic field-effect transistors (OFETs), 2, 5-8 organic light-emitting diodes (OLEDs), and organic photovoltaics (OPVs). Early successes include the application of self-driven laboratory workflows to screen quaternary OPV formulations at the full device level. Indeed, these endeavors have positioned organic electronics as a significant research thrust within the materials informatics community.