Each compound with a score above 0.7 is labelled as P&Dapproved based on the available data. The score is capped to not exceed 0.7 unless it passes all three core criteria (i.e., in vitro potency, cell potency and selectivity). Compounds labelled as historical are down-weighted by subtracting 0.3 and thus cannot be labelled as P&D-approved. Currently, there are 1,109 probes labelled as P&D approved. More details on this are given on the P&D FAQ page. The CPOC and CPOO scores (from 0 to 4 stars) are based on Scientific Advisory Board (SAB) reviews. These may be accompanied by comments and usage recommendations. However, there is currently a review backlog in that out of 362 compounds, 274 have been rated for use in cells and 225 for use in model organisms.