Control over activation rates enables encoding of molecular information processing. Since the compe�ng ac�va�on step is slow, we examined whether the �me at which the system is maintained at the basic pH, ∆tB, can be used for encoding informa�on (Fig. ). The �me at which the system is maintained at the acidic pH, ∆tA, can be used to reset the device. Depending on the choice of the �me intervals for the input pH (∆tA and ∆tB), one can encode informa�on such as the message 'CRN@UT' (our research group at the University of Twente, Fig. ). For this demonstra�on we used a sequence with ∆tB=5, 20 min and ∆tA=10 min to produce an output patern comprising mul�ple local maxima. We then assigned the output as (1) a 'dash', when 0.75 < local maxima < 1.0, or (2) a 'dot', when 0.25 < local maxima < 0.5, to yield the corresponding Morse code for 'CRN@UT'. The run�me of the experiment can be reduced or the density of informa�on can be increased when shorter �me intervals for the input pH (∆tB).