This study has demonstrated that achieving net-zero emissions across the lifecycle stages for chemical products is possible but requires the deployment of both supply-and demand-side interventions. The chemical industry should accelerate the development of technologies highlighted in this study (non-fossil feedstocks as well as CCS, MTO/P and MTA), and collaborate across different industries to drive resource efficiency and material circularity, to reduce demand and balance the carbon flows. Policies such as carbon pricing and mandates to bridge the cost gap across the supply chain are essential to accelerate investment in the chemical industry. Additional revenue streams from negative emissions may offer a new value proposition for the industry. Demand-side coalitions and changes to government purchasing can help drive future demand for net-zero chemicals. In conclusion, this work highlights planet compatible pathways for the chemical industry based on circular strategies and a new system service for sequestering carbon, while continuing to provide essential services to society.