Namely, JigSAP-IMI-Ox and JigSAP-MII-Ox remain dispersed in solution under a physiological condition (4 mM HEPES, pH 7.4, DMEM containing 1.0 wt% peptide concentration, Fig. and), whereas JigSAP-IMI and JigSAP-MII form hydrogels under the same condition (Fig. and). The phase transition from gel to sol is useful for drug and cargo release. Upon addition of 30% H2O2 aq. to the top of the hydrogels