Then, we conducted water dimer scans using symmetry-adapted perturbation theory (SAPT) to determine the different components of the interaction energy. By comparing with the SAPT results termby-term, atomic parameters were further refined (i.e., the atomic polarizabilities from ISA were scaled by 1.1 to reproduce the SAPT induction energy). After the asymptotic parameters were determined, the prefactors of the isotropic short-range interactions (see Eqn (8)) were fitted to the many-body training set at CCSD(T) level of theory (vide infra).