One of the common hindrances in bioceramics usage is the high amount of brittleness causing cracks in the scaffolds and implants. Other defects include heterogeneity, inclusions, porosity, and conglomeration of structural components. Proper densification and sintering and proper homogenization of reinforcement particles on the matrix phase for composites will toughen the matrix. The strategies include microcracking, crack branching, crack deflection, phase transformation, and bridging of fiber, particles, and whiskers . Another problem that bioceramics face is biocompatibility in biomedical implants and scaffolds used in wound healing, hernia repair, skeletal muscle defect repair, myocardial infarction, dental fixtures, etc. The biocompatibility tests are mainly conducted on rodents in an environment matching the human immune system and error minimization is a problem. Developing computational models for further studying human immune cell responses is, therefore, beneficial [26].