Alternating polarity is key up with minimal re-optimization (Figure ). To put this into context, secondary acid 69 was smoothly converted into a useful unsaturated amine 62 on 1 kg-scale, which could otherwise require tedious preparation via Diels-Alder followed by a series of functional group manipulations. This "reverse hydrocarboxylation" could be another entry for facile conversion of abundant carboxylic acids into high-value building blocks on scale.