Interestingly, traditional flexible ligand docking with the Vina scoring function did not identify this drug in the top 100 list. However, it is ranked third on the QFVinardo list. The figure below, created using the third-party DiscoveryStudio program for visualization, highlights numerous attractive interactions between the drug molecule and the protein. There is one unfavorable donordonor interaction that might be underestimated by both the Vina and Vinardo scoring functions, which could contribute to the falsely strong binding estimations. However, there are also several attractive hydrogen bonds and other favorable interactions, as the figure indicates.