For example, the symmetric bending mode of water overlaps with the calculated amide I', and prohibits to make further detailed comparisons of the amide regions in experiment and theory. As the spectra were simulated using the same scaling factor of 0.95 for the amide I (and I'), the microsolvation shows that the amide I (and I') modes using only C-PCM are indeed overestimated (as noted above) and need this higher scaling factor to align this spectral region with experiment.