In this work, we have outlined the influence of rotating molecular species and the importance of their orientation, cooperativity and directionality on the transport properties of confined fluids. Our findings help to understand the influence of local dynamics of molecular motors and rotors on the surrounding fluid. This includes, the nature of pore space functionalized with dynamic groups and potential strategies to manipulate transport properties of confined fluids by this dynamic pore space. Although the applied model drastically simplifies real-world molecular motors, it captures the most important aspects being unidirectional rotation and orientation of the rotor. Our results, however, provide helpful indications about the need of high rotational frequencies in addition to the detection of minor changes in diffusivity locally and globally. We envision the guidelines, presented here, to be crucial for the design of stimuliresponsive dynamic materials, capable of manipulating guest transport properties by dynamic molecular machines. However, the currently reported porous materials that include molecular machines or rotors do not meet the specified criteria defined by this investigation.