Å-particles in the original box, due to the single σ ij = 6.7 Å-solute. We estimate this volume by using the fitted radius of the excluded volume in fig. . For 100 Å box sides, this change constitutes a reduction of the total volume by less than 0.1 %. Yet, this minute change gives the differencescattering signal ∆I ρ (q), displayed with blue in fig. . There is a noticeable agreement between the high-q solvent-solvent feature in I v (q) and the global average density increase, indicating that this feature arises from the global density increase of the bulk solvent. The differences between the black and blue curve in the high-q feature must arise from the the inaccuracies in exactly determining the excluded volume from the simple model discussed previously (see fig. and accompanying text), as well as the fact that the signal from the global density increase does not contain any local solvent shell structure. We thus conclude that the high-q feature is a finite-size effect due to the fixed volume of the simulation cell.