To conclude, the presented mean-field model of weakly charged microgel turns out to be precise for describing swelling and net charge in a wide range of microgel sizes and system conditions. The model consistently accounts for the inherent coupling between microgel swelling, charge regulation and ion partitioning, effects that are of paramount importance in determining effective interactions and consequently suspension stability, as well as microgel loading. Furthermore, the model also relates the swelling behavior with various molecular properties and synthesis features, offering an advantageous tool for the rational design of microgels. The presented model provides a versatile and rapid method for screening parameters in the composition and layout of microgels, reducing exploration time from weeks with coarse-grained simulations to hours with the nonlinear model, and even to minutes with the linear analytical approach. This aspect is particularly relevant for biomedical applications, given the significant potential of weak microgels as smart drug carriers. Accordingly, we will apply the model to more sophisticated architectures such as core-shell microgels in the future. Moreover, the behavior of microgels with coexisting acid and basic sites (polyampholyte microgels) will be explored. These systems are of significant interest in light of their phase behavior. Nevertheless, due to the neglect of correlation effects and the microscopic chain structure, there are still important physical effects that are not properly captured by the model. Further theoretical studies should accordingly focus on how to extend the model by approximately including these effects.