The second option is to alter the perceived utility of HTCS. Many technical barriers exist between identifying MOFs through HTCS and translating them into real, industrially viable separation materials. To name a few, a MOF must demonstrate good mechanical, thermal and moisture stability, low cost, and scalable synthesisability. A prime example is CALF-20 which, despite its relatively modest process-level performance (see supplementary note 10), is the only known MOF to satisfy enough of these technical requirements to succeed as a viable industrial-scale adsorbent. Therefore, rather than identifying the best performers via material rankings which we understand suffers from some reliability issues, one can instead try to identify good performers using HTCS and then shortlist materials based on all other factors which dictate the feasibility of an adsorbent. Given the importance of these material attributes, this approach could provide more meaning to the results