4. An organic unknown was correctly identified as quinoline, C 9 H 7 N, by OpenAI models ChatGPT-5 preview, ChatGPT-4o, and Organic Chemistry based on chemical spectral image analysis and the provided molecular formula. ChatGPT-5 preview provided the best reasoning as to how it solved the problem . The next manuscript featured 3.5 Sonnet providing a convincing solution to tabulated data provided by the manuscript author based on 13 spectral images and the molecular formula. Shortly after the manuscript was published, o1-preview was released, which also provided the same answer of (S)-ibuprofen ethylester, C 15 H 22 O 2 .