Empirically, we have observed that electrochemical aptamer sensors employing MCH passivation layers are quite stable when testing at refrigerated (~4 °C) or room temperatures (~20 °C) in buffer conditions (Figure ). This is also corroborated in the literature, where sensors stored at room temperature survived >7 days in solution. However, changing the testing environment to body temperature (~37 °C) leads to more rapid degradation, consistent with literature on temperatureprogrammed desorption for pure alkylthiolate monolayers on gold.