To further showcase the practicality of this transformation, we conducted a gram-scale synthesis of compound 4aa (Scheme 4A). With a 5 mmol scale of dihydroquinazolinone 2a as starting material, 749.8 mg of compound 4aa were isolated, despite with lower yield compared with that in a 0.2 mmol scale. Furthermore, we also investigated the feasibility of in situ generation of 2a and its one-pot gem-difluoroallylation reaction with 3a. Gratifyingly, the desired gemdifluoroallylated product 4aa was isolated in 47% yield in a 1 mmol scale preparation (Scheme 4B).