In other words, the substrates in TSwyn2A(S) are not only more stable but also interact more favorably with the catalyst, than do those in TSwyn2A'(R). The results of the EDA analysis are shown in Table , and indicate clearly that the large energy separation between TSwyn2A(S) and TSwyn2A'(R) mainly arises from differences in the interaction energy (ΔΔEint = 5.0 kcal/mol).