We sought out to design an optimized formulation by setting up a stability study composed of Peptide A formulations spanning a wide range of pH's, buffers, and excipient concentrations. The stability study utilized both long term (5°C) and accelerated (25°C, 40°C) conditions with a target storage condition of being refrigerated. Given that pH was closely linked to chemical and physical stability formulations were designed to explore a wide pH range of 7.5-8.7 to define a formulation with an optimized pH. In addition to pH, compositions of multiple excipients were varied including histidine (0 to 10 mM) and a proprietary excipient B (EB) (0-0.5% w/v) which were targeted to improve chemical and physical stability, respectively. The addition of histidine was to prevent the growth of a specific degradant and is not expected to have a dramatic effect neither on the potency nor the total degradation of the peptide. Therefore, the addition of this excipient can be used as a case study for changes to the formulation that are not designed to make a dramatic impact on the output variables. The goal of the stability study was to optimize the pH and excipient compositions and determine if it was achievable to design a formulation with acceptable physical and chemical stability over the course of Peptide A's shelf life.