Lantibiotics represent another class of antimicrobial peptides that target lipid II, the critical precursor in bacterial cell wall synthesis, and display a dual functionality similar to lipo-glycopeptides, combining cell wall inhibition with membrane-disruptive action. Lantibiotics are ribosomally synthesized peptides characterized by the presence of lanthionine (or its close relative, methyl-lanthionine), as well as other non-canonical unsaturated amino acids like dehydroalanine, and 2aminoisobutyric acid .