related to the handedness of the helical terpolymer, which can be switched in two opposite directions by selecting the main BTA enantiomer in the terpolymers at each step of the reaction, leading to predictable configuration of two stereogenic centers. The stereochemical switch occurs through the addition of the BTA enantiomer acting as a chiral chemical trigger that inverts the stereochemical preference of the copper catalyst. The achiral BTA additive present in the supramolecular terpolymer, as well as the secondary phosphine ligand, improve the selectivity and yield of the reaction, respectively. Not only a fine tuning of the chirality of the supramolecular assemblies but also a proper control of their dynamicity is key to address stereodivergency. The present work demonstrates the feasibility of the concept to select one major (70%-79%) amongst four possible stereoisomers of an amino alcohol by applying the supramolecular helical catalyst in either concomitant (with no inversion of catalyst handedness) or sequential (with inversion of catalyst handedness) hydrosilylation and hydroamination reactions. The supramolecular helical catalyst proves to be less efficient in the sequential process, notably because of its decreased activity and selectivity for the hydrosilylation step. The concept has been demonstrated for copper hydride type catalysis but can be reasonably extended to other catalytic processes and to the control of more than two stereogenic centers in small molecules or polymers. It is also conceivable that the catalytic properties and the dynamicity of this class of supramolecular helical catalysts can be improved by a proper design of the molecular structure of the monomers. Work along this direction is currently underway in our laboratory.