To obtain the benefits of functional molecule synthesis from locally sourced bio-renewables, efficient and clean process operation is imperative. In this work we calculated the environmental impacts of an industrial-scale flow synthesis process for the manufacture of paracetamol from CST-derived β-pinene. For this purpose we used the Life Cycle Assessment (LCA) methodology, a widespread and standardized tool to evaluate environmental process impacts across various life cycle stages. To quantify the required Life Cycle Inventory (LCI), it was necessary to develop models of every step of the proposed process using experimental and literature data, from which values of material consumption, energy requirements and process emissions could be extracted. The obtained LCI data was employed to conduct cradleto-gate LCA of the proposed process, the results of which were used to: (i) compare the environmental efficiency of the CST-derived β-pinene feedstock to petrochemical-based benzene feedstock, (ii) estimate the environmental burdens of the β-pinene-based paracetamol manufacturing process, and (iii) identify hotspots of the case study process to guide future process optimisation.