Additionally, the substrate scope of this C-H biarylation was examined (Figure , right). The results indicated that the reaction is applicable to various different biaryl linkages. Compounds like 37, which exclude the phenolic OH of tyrosine, and compounds with different substitution positions on tyrosine, such as 38, proceeded with good yields. Moreover, the biaryl linkage substituted with fluorine, proved to be significant in medicinal chemistry, also reacted successfully, yielding 77% (5.3 g) of the desired compound 39 on a gram scale.