Within this section, we present the results on the freezing of a box comprising 20x12x3 (i.e. 720) vials. The additional element of complexity compared to the 2x2x2 system lies in the positiondependency of freezing, whereby vials at different positions within the system experience a different heat transfer and thus thermal evolution. For a system of this size, it is not helpful to plot the thermal evolution of all vials when aiming at understanding the process. Instead, we prefer to show the temperature of all vials at a few points in time in the form of heatmap snapshots to achieve a system-scale understanding of the process. Figure illustrates such evolution for three points in time and a storage temperature of -20°C. Figure shows that corner and edge vials cool down and nucleate faster than their inner counterparts; bright spots indicate vials that are solidifying at the specific time shown in the figure. Vials in the central layer nucleate later than those in the top and bottom layers. It is noteworthy that with this type of representation, thermal interaction can be studied in a direct manner; one indeed observes that some vials are hot spots in the system and heat up their neighbors. We therefore opt for a different visualization, i.e. the cumulative distribution, when assessing the impact of the external temperature on the freezing behavior.