The globally available strains for C. albicans and C. neoformans, namely ATCC 90028 and H99 respectively, were used to assess the antifungal potential of the panel of cobalt complex compounds in the G. mellonella insect model. Each strain was cultured on Sabouraud's Dextrose Agar (SDA) for 24-48 hours at 27°C prior to inoculation. Yeast colonies were then suspended in phosphate-buffered saline solution (PBS) and cells concentrations were adjusted using a Neubauer counting chamber to 5 × 10 7 cells for ATCC 90028, and 1 × 10 8 cells for H99.