The global hybrid meta-GGA (Group 4) functionals (median = -53.8 kcal mol -1 in Figure ) come closest to the ΔEe(rxn) benchmark and could be considered the best performing group if not for the poor results (-9 kcal mol -1 ) from DLDF, DLDF+D09, and DLDF+D10. The minimum Group 4 prediction is -61.7 kcal mol -1 from M05-D3(0)ATM, and the interquartile range (IQR) is 5.7 kcal mol -1 . Of the three Group 4 DFAs included in and ωB97m-V (96.5%-ile). Across Groups 3, 4, and 5, no results for DFAs in Table are below 50%-ile, in sharp contrast to Group 6. In summary, the overall DFT performance highlighted in Figure does not monotonically increase with group numbers but reaches a maximum (arguably)