Compound 12 H NMR (400 MHz, CDCl3) δ 7. A 50 mL round-bottom flask was charged with a stir bar, 12 (0.820 g, 1.55 mmol, 1 equiv.), DMSO (20 mL), and KOAc (0.610 g, 6.21 mmol, 4 equiv.). The reaction vessel was then submerged in an oil bath preheated to 80 °C and kept at this temperature under a balloon of N2 (~1 atm) for Following this time, the reaction was cooled to room temperature, diluted with water (80 mL), and transferred to a separatory funnel. The aqueous layer was extracted with EtOAc (2 x 50 mL). The organic layers were collected, dried over Na2SO4, and concentrated under reduced pressure. The resulting residue was purified using a gradient of 0 to 20% EtOAc/hexanes on silica gel to yield 13 (colorless oil, 0.661 g, 1.30 mmol, 84% yield).