exhibit large uncertainties when relying on a 2σ d S T threshold to achieve 95 % confidence. For the temperatureinduced S T changes, the uncertainties are 11 %, 67%, and 37 % and, for the pressure-induced S T changes, they are 15 %, 622 %, and 23 % for mixtures A, B, and C, respectively. We used the S T uncertainties σ S T from the NEMD simulations to obtain the uncertainties σ d S T and applied conventional uncertainty propagation rules, which yields, for example, for the temperature-induced relative S T change