Today butadiene is in high demand, but it also had a historical importance in production of synthetic rubber, for which it was produced during World War II. Styrene is widely used in polymer production (homopolymers, copolymers or rubber-modified polymers), while ethanol was a raw material for production of acetic acid; it is now used as a solvent in cleaning, cosmetics and coatings industries, as industrial solvent and reactant, and is also converted to white vinegar. Furthermore, ethanol is used as an octane-enhancer or petrol replacement in the automotive fuels market. 66 All these chemicals have shown major industrial significance in the past and present and are, therefore, correctly identified by the algorithm as strategic molecules. Further, the algorithm detects acetone and phenol as derivatives from propylene.