In a separate and recent analysis, constellation plots were used to uncover a promising analog series of inhibitors of tubulin-microtubules. In that study , the authors analyzed the SAR of a curated dataset of 851 compounds with anticancer activity targeting tubulin-microtubules. In particular, the constellation plots identified at least six analog series of compounds with high average activity (known as "bright regions" in chemical space). The plot also indicates an analog series with predominantly inactive molecules ("dark regions" in chemical space). In recent developments, constellation plots have been implemented in DataWarrior such that the user can explore the chemical space interactively.