Functionalization of commercial polymers via copolymerization leads to a variety of polymers with interesting properties. Halogen ring-substituted ethyl 2-cyano-3-phenyl-2propenoates (HECP) offer a convenient way to introduce a variety of functional groups in polyvinyl acetate backbone. 2-Bromo HECP is reported in preparation of highly loaded MWCNT-polyamine hybrids and their application in catalysis , as well as in synthesis of thiazacridine derivatives as anticancer agents against breast and hematopoietic neoplastic cells . 3-Bromo HECP is involved in synthesis of novel selenophenes from activated acetylenes, ethyl 2-cyano-3-arylacrylate and potassium selenocyanate , also in straightforward preparation of highly loaded MWCNT-polyamine hybrids and their application in catalysis . The report on design, synthesis, anti-proliferative evaluation and cell cycle analysis of hybrid 2-quinolones cites 2-chloro HECP . Novel synthesis of 3cyano-2-pyridones derivatives catalyzed by Au-Co/TiO2 involves 3-chloro HECP . This HECP also was involved in the study of selenotungstates incorporating organophosphonate ligands and metal ions describing synthesis, characterization, magnetism and catalytic efficiency in the Knoevenagel condensation reaction . 4-Chloro HECP was reported in the study new hybrid organic-inorganic multifunctional materials based on polydopaminelike chemistry . 2-Fluoro HECP was mentioned in study of optimized monofluoromethylsulfonium reagents for fluoromethylene-transfer chemistry . Discovery, stereospecific characterization and peripheral modification of 1-(pyrrolidin-1ylmethyl)-2-[(6-chloro-3-oxo-indan)-formyl]-1,2,3,4-tetrahydroisoquinolines as novel selective κ opioid receptor agonists involves 3-fluoro HECP . 4-Fluoro HECP was mentioned in study of aerobic oxidative cleavage of C=C bond to carbonyl compound .