To demonstrate the capability of our workflow, we have applied this new workflow to the large-scale database of inorganic materials from the Materials Project, consisting of more than 170,000 structures -the first systematic determination of topology in a materials database of this size. This allowed us to report a statistical analysis of the most frequent topologies and coordination environments, and publish this information online to allow researchers to search for materials by topology and chemical environment. This will pave to way to more efficient search in materials screening for applications, by allowing to include more chemical insight and restrict the search space to specific topology, bonding patterns, coordination environments. While we demonstrated two examples of the usefulness of topological considerations in such computational screening, we believe that this will be useful for many applications. It is one more tool in the toolbox of the materials researchers -beyond its use in high-throughput screening, it will also be usable to experimentalists through the user-friendly MPContribs framework on the Materials Project website.