The remainder of this paper is structured as follows: First, in Section 2, the reader is provided with the relevant background for single-step retrosynthesis frameworks. The methodologies for the benchmarking pipeline and interpretability study are outlined in Sections 2.2 & 2.3, respectively. Thereafter, the results of the benchmarking and interpretability studies are presented in Sections 3.1 & 3.3, respectively. The paper concludes with an outlook of what future research could entail (Section 4).