The coarse-grained model coupled with DPD also shows that at high surface coverage, some of the asphaltenes molecules desorbed into the oil region due to the steric hindrance between adsorbed particles (Ruiz-Morales and Mullins 2015). Experiments involving desorption of adsorbed asphaltenes using rinsing procedures suggest that asphaltene adsorption at oil-water interface is irreversible ). The molecular composition and heteroatoms such as oxygen, nitrogen and sulfur in asphaltene molecules impacts the asphaltene adsorption Gibbs free energy at the oil-water interface . The charge of heteroatoms determines the strength of hydrogen bond with the water molecules and, thereby, the stability of asphaltene adsorption at the oil-water interface .