and -T S h,W ⊕C (z) are large and in opposition relative to their bulk values, with repulsive E h,W ⊕C (z) and attractive -T S h,W ⊕C (z). These large changes in the solutesolvent energy and entropy are to be expected given our classification of the C 12 E 6 monolayer as a nonpolar medium, such that removing the ionic SO 4 CH - 2 from polar water into the less polar C 12 E 6 leads to repulsive electrostatics, and a simultaneous de-structuring of the surrounding solvent (i.e. bulk water is structured around SO 4 CH - 2 , while C 12 E 6 is less structured around SO 4 CH - 2 at the interface). The thermodynamics of SO 4 CH - 2 adsorption to the AWI shown in Fig. is similar to that of adsorption to the ACWI, with large competing energetic and entropic components that mostly cancel each other up to the free energy minimum.