Compound datasets (DS) were built with ChEMBL, version 26, PubChem, and scientific articles. For ChEMBL, the following identifiers were used: LasR -CHEMBL1075207, PqsR -CHEMBL2424500, and RhlR -CHEMBL3112386. In PubChem Bioassay, the search was done directly with the AI's. Additionally, for the previous search, only molecules IC 50 and EC 50 values were taken into account. Keywords' LasR', 'PqsR', 'RhlR', 'Quorum Sensing' were used to search for molecules in scientific articles in SciFinder. Then all papers were filtered by their biological activity values 'IC 50 ' or 'EC 50 ', taking into account all articles published between1998 and 2020. This search was carried out between January 2020 and July 2020.