Here, we demonstrate for the first time a framework for chemical synthesis in the aerosol phase which is fundamentally designed for programmable execution. In what follows, we will outline directions for future development in the area, including tackling limitations of this current system. Aerosol properties, critically size distribution, are known to have a strong dependence on relative humidity -and for non-aqueous solvents, solvent vapor pressure -which is not currently taken into account. Relying on short, isolated bursts of aerosol release, we have sought to minimize the change in relative humidity from ambient due to the evaporation of reagent solutions. In parallel, we are working on a reactor with closed-loop active humidity control in which relative humidity. can be maintained at any desired level throughout the course of the experiment.