The overall performance of ddX is remarkably good. For the largest system, which consists of more than 138,000 atoms, the total time required to compute the energy ranges between 3 minutes for ddCOSMO, 4 minutes for ddPCM and 56 minutes for ddLPB, the timings increasing to 9, 10 and 204 minutes respectively, if also the forces are computed. We remark that the timings were obtained on a single computer node equipped with two Intel Xeon 6252 Gold CPUs, which is commonly available hardware, and that the results are obtained using conservative discretization parameters, that ensure no compromise on the accuracy of the compute gradients.