On the basis of these considerations and alongside the data, we selected an HTM-ST chicane-type mixer operating at an ArBr : RLi : electrophile flow rate of 2.125 : 0.438 : 0.765 mL min -1 as the central component of our reactor design. In parallel, we examined a reactor consisting of 250 μm Tee pieces and operating at an ArBr : RLi : electrophile flow rate of 4.25 : 0.875 : 1.53 mL min -1 as a lower cost alternative.