Comparing the transition matrices of the three systems, we also observe that, as the ε increases, it becomes less likely to observe monomers and small aggregates. At ε = 40 kJ mol -1 , the disassembled monomers have a ∼ 60% probability to remain isolated at every ∆τ (Figure :left). The probability drops to ∼ 52% and ∼ 49% for the systems with ε = 45 and ε = 50 kJ mol -1 cases (Figures 3a:left and S14b:left, respectively).