In this study, we used high-throughput Phase-field modeling to investigate the impact of various parameters on grain coarsening. Our Phase-field model allowed us to explore the effects of particle shape as defined by its aspect ratio ( ), particle volume fraction (V f ), particle size (P d ), mobility (M ), and surface-to-grain boundary energy ratio (γ r ) on grain growth in a polycrystalline matrix phase. The parametric values were non-dimensionalized and presented in Table . To analyze the microstructures of grain coarsening in the presence of second-phase precipitates, we considered representative simulated microstructures, as shown in Figure (a)-(f). Furthermore, we plotted the corresponding grain size versus the time plot, as shown in Figure . The results demonstrate that grain boundaries reach a limiting size at the end of the simulation in most cases, which is consistent with Equation . We performed simulations over a wide range Figure : The impact of different factors on Zener pinning is investigated using Phase-field modeling. Panel (a) shows a small-sized spherical particle with a large volume fraction of 0.1, which results in a more significant pinning effect. Panel (b) depicts a small particle with a low volume fraction of 0.025 and a high aspect ratio ( ), which results in an elongated grain shape due to the preferred growth direction parallel to the particle's long axis. Panel (c) shows a small-sized spherical particle with a low volume fraction of 0.025 and a lower surface-to-grain boundary energy ratio, which results in a reduced pinning effect. In panel (d), a small-sized particle with a low volume fraction of 0.025 and a high mobility of 1.0 is depicted, resulting in reduced pinning and increased grain growth. Panel (e) displays a large-sized spherical particle (12 nm) with a low volume fraction of 0.025, which exhibits a weak pinning effect. Lastly, panel (f) illustrates a small-sized spherical particle (4 nm) with a low volume fraction of 0.025, resulting in a weak pinning effect and a near-uniform grain size distribution.