The software is versatile and can be used to cross different CG scales, provided that a well-sampled reference trajectory is available for the molecule to be coarse-grained. Swarm-CG can satisfy molecular modelers' requirements for routine building of CG models composed of up to 200 CG beads (in the MARTINI framework, this corresponds to molecular architectures containing at least ~600-800 heavy atoms), and possibly more, both in terms of accuracy and execution times. We particularly expect this tool to support the development of new CG molecular models for the study of synthetic molecular systems and their interaction with other (bio/non-bio) molecular targets, as it is becoming increasingly crucial in the various bio-and nano-technology fields. Swarm-CG is available via PIP (package: swarm-cg) with all its dependencies. Tutorials and demonstration data are also available at www.github.com/GMPavanLab/SwarmCG.