The HTH marR-type (IPR000835) is a DNA-binding winged helix-turn-helix (wHTH) domain that is associated with the development of antibiotic resistance. It is a MarR-type HTH domain that is present in the MarR/SlyA family's transcriptional regulators. The MarR family of transcriptional regulators is named after Escherichia coli MarR, a gene repressor that activates multiple antibiotic resistance and oxidative stress regulators.