To monitor enzymatic degradation progress, the samples underwent analysis for mass loss, molecular weight, morphological, and structural changes. Mass loss was quantified using equation ( ), where m0 is sample mass before degradation and md is a mass of vacuum-dried sample (37 °C, -60 kPa, 48 h) after degradation. Molecular weight analysis was performed via Size Exclusion Chromatography (SEC) using a Thermofisher (HLC-8320) system equipped with four detection systems: a dual absorbance UV (UV, Waters 2487, wavelength λ = 254-280 nm), multi-angle laser light scattering (MALLS, Wyatt DAWN), a refractive index detector (RI, Wyatt Optilab®), and a viscometer (VIS, Wyatt ViscoStar®) detectors. The determination of average molar (apparent) mass (Mn, Mw) and dispersity (Đ, Mw/Mn) was carried out through gel chromatography. The mobile phase used was CHCl3 (HPLC grade, Alfa Aesar) at a flow rate of 1 mL/min, with a sample concentration of 15 mg/mL and an injected volume of 50 µL. Before injection onto the column, the sample solutions underwent filtration using a 0.20 µm SRP 20 filter. Absolute molecular masses were derived by processing the data with ASTRA version 8.1.2 software, assuming 100% recovery from the columns. Structural alterations were evaluated through Attenuated Total Reflection-Fourier Transform Infrared (ATR-FTIR) spectra, recorded on a Bruker ALPHA spectrometer within the spectral range of 400 to 4000 cm -1 , employing a resolution of 2 cm -1 . Notably, 32 scans were conducted for each sample. Morphological changes were examined utilizing a scanning electron microscope (SEM) equipped with ultra-high resolution (UHR), specifically on a Hitachi SU8020 apparatus.