In this paper, we demonstrate Pickering-emulsion-type stabilization and functionalization of the surface of DNA condensates using DNA origami 28 nanoparticles (Figure ). Pickering emulsions are particle-stabilized emulsions whose mechanism has been widely used to stabilize and functionalize water-in-oil droplets, oil-inwater droplets, and LLPS condensates. Recently, DNA origami nanoparticles have also been applied to the functionalization and stabilization of Pickering emulsions. In general, the particle properties such as large diameter, non-spherical shape (e.g., a rod and a plate), and affinity to condensate are important for interface stabilization; especially in the case of LLPS condensates, that is because of their low surface tension .