With this methodology we eliminated 99.99% of the original reactions. Among product molecules satisfying all six principles, 24 were identified as potential interstellar species. Of these, five (isocyanic acid, formic acid, formamide, methyl isocyanide, and HCCN) have already been detected in the ISM List of interstellar and circumstellar molecules (2024), which shows the effectiveness of the screening procedure. The remaining 19 molecules, including three we reported earlierJi et al. (2023b), are the focus of this study.