To prepare for consensus or confirmatory docking, the DW-BEL resulting fitted-children were filtered to exclude any remaining toxicities and/or nasty functions to yield non-toxic fitted-children. A DW macro filter including hundreds of mutagenesis, tumorigenicity, reproductive interference and irritant molecular signatures, and/or nasty functions was designed for these purposes . The non-toxic fitted-children were DW saved as special 3D *.sdf files using previously described options including mmff94s + minimization . Such saving methods were critically required to preserve their 2D geometries for PyMol visualization (split_states PyMol command) and/or for optimal ADV re-docking.