Another emblematic approach to such molecules utilizes reliable C(sp 2 )-C(sp 2 ) Suzuki-Miyaura couplings followed by hydrogenation. This conventional strategy, often applied to secondary carbons, leverages the formation of a vinyl halide starting from the corresponding ketone, followed by Miyaura borylation and the cross-coupling step, after which the hydrogenation of the undesired alkene is required. This sequence usually requires protecting groups and chemoselectivity issues can arise when other reducible or basesensitive functionality are present. On the other hand, radical cross-coupling of the carboxylic acid overcomes the necessity of the aforementioned FG interconversions and concession steps to address chemoselectivity issues. Whereas traditional approaches often require three separate uses of Pd-catalysts, the DCC-approach employs a single Ni-catalyst to forge the key carbon-carbon linkage with the correct oxidation state.