Small Angle X-Ray Scattering of COF-300 nanoparticles: SAXS measurements were performed at the SAXS-WAXS service at IQAC using an S3-MICRO (Hecus X-ray systems GMBH Graz, Austria) using a GENIX-Fox 3D X-ray source (Xenocs, Grenoble), which produces a detector focused X-ray beam (λ = 0.1542 nm, Cu Kαline with more than 97% purity and less than 0.3% Kβ). X-rays were detected by means of a PSD 50 Hecus. The X-Ray path is kept under vacuum and the liquid sample was injected in a flow-through glass capillary (1 mm diameter and 10 μm wall thickness Hilgenberg Mark glass Nº4). The temperature was controlled by a TCCS-3 Hecus Peltier system set at 30 ºC to avoid surfactant precipitation. The system was calibrated by measuring a standard silver behenate sample and put in absolute intensity by comparison with water. Because of the use of a detector focused small beam (300 x 400 μm full width at half-maximum), scattering curves are smeared by the detector width and depth. The instrumentally smeared experimental SAXS curves were fitted to numerically smeared models for beam size and detector width effects using a custom least-squares routine based on the Levenberg-Marquardt algorithm. The measurement started shortly after mixing and successive twenty minutes accumulations were recorded. These files were checked for changes. No significant changes were detected for the first hour and its summation was taken as the background to be subtracted from one-hour accumulations.