Protein Multimodal Network (PMN) model a novel model proposed by , with the superiority of being able to augment multiple protein-related informations (Multimodal), these informations include; primary structure sequences, and 3D structure residue-level graph and geometry. One of the successful cases, TargetVAE, a model that generates ligands that bind to specific proteins, with customized properties such as binding affinity and high synthesizability.