Nanotechnology-driven cell engineering has contributed various kinds of nanomaterials, such as gold , and silver nanomaterials, as cellular control manipulators. Particularly, gold nanomaterials are the most widely utilized because of their high stability , their low side effects, the ease of handling their synthesis process , and their shape-dependent optical properties . For example, gold nanorods (GNRs), which are anisotropic rod-shaped gold nanomaterials, absorb near-infrared (NIR) light and convert it into local heat. Since NIR lasers penetrate cell components and water, they are utilized for heat-induced gene regulation, in drug-delivery systems, and for cancer therapy .