This has significant implications for counterpoise correction schemes that can be used to address BSSE but which have historically been underutilized in fragmentbased quantum chemistry, perhaps due to cost. The data in Fig. ) demonstrate that error increases as the number of high-order subsystems is reduced by more aggressive screening, which suggests that most of the high-order terms in MBE(n) contribute nothing more than incomplete error cancellation. Counterpoise corrections for MBE(n) and its generalizations have been developed but are not yet implemented in our code. These methods introduce an additional combinatorial scaling factor but aggressive energy screening may render these corrections tractable.