fered from low DQ filtering signal) had an optimal excitation time of 4.8 ms (9.6 ms mixing time) for the middle CS environments, as determined by MQ-SC experiments (Figure and S16). We ensured that the recycle delay and excitation times were set appropriately based on experimental relaxation parameters (See Figures and). We employed these optimal parameters for spin counting experiments utilizing the SR2 8 pulse sequence to count the even and odd coherence orders (Figure ). When examining a MQ-SC profile in order to determine the minimum number of clustered spins, any odd coherences shown for the even order MQ-SC profile (and vice versa) can be attributed to experimental noise and MQCO leakage caused by imperfect filtering of the double quantum recoupling sequences (Figure ). The zero order coherence for even MQCO profiles is attributed to z-magnetization of the spins.