In Table , we review three examples of compounds with assigned probe scores. The first is a selective RIPK1 inhibitor, GSK2982772 (LYPAFUINURXJSG-AWEZNQCLSA-N), highly scored by all three probe sources. The second is BET family bromodomain inhibitor from SGC Probes, JQ-1 58 (DNVXATUJJDPFDM-KRWDZBQOSA-N), scored highly by P&D and Chemical Probes Portal, but as a family-selective probe with lower PMIS. The latter is the only P&D approved probe with low ratings from the Chemical Probes Portal (not scored by Probe Miner), AGI-5198 (FNYGWXSATBUBER-UHFFFAOYSA-N), was proposed as a prototypical IDH-1 R132H inhibitor. However, this was surpassed in potency and characterization details by the more recent GSK864 60 (DUCNNEYLFOQFSW-PMERELPUSA-N) which also has an inactive control for proof of target involvement. However, as a second, distinct chemotype, this probe could be used for corroborative phenotypic assays.