Quantitative analysis of SC-containing e-liquids in the literature suggests a concentration range of ~1-25 mg/mL, compound dependent. To assess our ability to detect at real-world concentrations, SC-containing e-cigarettes were prepared and artificially smoked using the e-cigarette drug detection device (EDD). Direct spectral measurements were performed on removed filters using a UV-VIS spectrometer and a 265 nm LED, identical to the EDD light source. Measurements were taken on the side of the filter facing optical detection elements, rather than the e-cigarette mouthpiece.