These best practices are tested in a realistic search scenario, where we found candidate oligomers tailored specifically to each of the three chemical properties explored. After vastly expanding our search space, the GA runs in these trials were able to self-terminate appropriately and found candidates as good as or better than the best candidates in our original limited search space. This indicates that our GA method with self-termination and tuned hyperparameters is proficient in efficiently locating top chemical structures for a variety of different properties and is a recommended starting place for general use.