Here, we demonstrate the successful integration of COF-300 nanoparticles into magnetic microrobots using our earlier reported biotemplating procedure (Figure ). A helical-shaped Spirulina platensis was selected as a natural scaffold (Figure ) and subsequently coated with pre-synthesized Fe3O4 magnetic nanoparticles (Figure ) to confer magnetic functionality (see SI for further details). Additionally, a glycerol/gelatin solution was used to coat the magnetic biotemplates with COF-300 nanoparticles. The COF-300 nanoparticles successfully adhered to the surface of the biotemplates, forming the COFBOTs. SEM images and energydispersive X-ray spectroscopy (EDX) maps confirmed the complete coverage of the magnetic biotemplate with the COF-300 nanoparticles (Figure and Figure , respectively).