The efficiency of the different dimeric ligands was also characterized in competition experiment within a cellular model of infection. First, Jurkat cell expressing either DC or L-SIGN were incubated with Ebola pseudovirus in the presence of the PM dimers (PM68, PM69, PM70 and PM74) at 5 µM or 500 nM (Fig. ). Jurkat cells were then washed and co-cultured with Vero E6 adherent cells. Cells were then lysed and assayed for luciferase expression. studies, since it provides stronger inhibition at a 500 nM concentration than PM69 (94% vs. 84%).