In the fall semester of 2022, two projects were designed. The first project (Project 1: Kinetic modeling of chemically fueled assemblies) was to build kinetic models from experimental data in the domain of theoretical chemistry for the 3 rd semester students for 4 months. For the details of chemically fueled assemblies, several research works are referenced . Bacially, to construct chemically fueled assembly, the building elements should include an activation/deactivation reaction cycle, a non-assembling precursor, and a self-assembling product (Figure ). Specifically, a molecular precursor that cannot self-assemble is converted to a product that can self-assemble into ordered structures after reacting with a high-energy molecule. This conversion reaction is the activation reaction and the high-energy molecule is the chemical fuel that is irreversibly converted to waste. The deactivation reaction which converts the product back to the disassembled precursors constitutes the second reaction in the activation/deactivation reaction cycle. Consequently, the assemblies are only present for a finite time until the chemical fuel is depleted and can be regenerated by resupplying the chemical fuel. Sustaining the non-equilibrium assembly thus requires continuous input of the chemical fuel. Such transient assemblies are accessible to accurate temporospatial programming by controlling the kinetics of the reaction cycles. The participating students at the same time were taking the courses of physical chemistry and organic chemistry. This PBL project required the students to build the kinetic model based on the understanding of the fundamental principles in interdisciplinary area of physical chemistry and organic chemistry.