This research challenges the obtainment of carbohydrate-conjugates based on the trithiolato dinuclear scaffold as potential antiparasitic drugs. For this purpose, a carbohydrate moiety was pended on one of the bridge thiols using 'click' reactions. The nature of the carbohydrate (acetyl protected glucose or galactose) and the type and length of the linker between the two units, were addressed as sources of variability. The new diruthenium hybrids and intermediates were screened in vitro against T. gondii tachyzoites expressing β-galactosidase (T. gondii β-gal) grown in human foreskin fibroblasts (HFF) with complementary assessment of HFF viability using alamarBlue assay. The compounds showing promising antiparasitic activity and selectivity were further subjected to dose-response (IC50) determination on T. gondii β-gal.