have similar activity profiles against the fungal panel, but the free ligand alone shows no activity suggests that a metal is essential to obtain the observed antifungal activity. Both complexes also contain a metal in their counterion. The compound K2[PtCl4] was tested against the fungal strain Sporothrix schenckii in another study, where it showed no activity at the highest tested concentration, suggesting that it may not be contributing to the antifungal activity observed in this work. The cytotoxic and haemolytic properties of the two compounds are slightly different, with Pd3 displaying low cytotoxicity and significant haemolysis. On the other hand, no haemolysis up to 200 µM could be detected for Pt5