reduction. Compared with the improvement in terms of greenhouse gas emissions, where, highpressurized columns saved almost 10% more. Most recently, for a minimum-boiling azeotrope of THF-water, Luyben , in a double continuous mode rectifier with vapor recompression, delimited LP/HP working pressure conditions to a vacuum of (0.6 atm)/above technical (11.3bar): outperformed "traditionally researched scheme" (Luyben ), by 19.4% in TAC, whereas, 40.15% with heat integration.