The resulting reaction energy difference ∆∆E (Eqn. ( )) for the reaction from methyl eugenol to trans-methyl isoeugenol in combination with the experimentally measured yields are shown in Fig. . It clearly can be seen that the highest yields can be observed for vanishing energy differences ∆∆E ≈ 0 in good agreement with our assumptions. Accordingly, We also calculated the resulting reaction energy difference ∆∆E (Eqn. ( )) for the reaction from methyl eugenol to cis-methyl isoeugenol. The results in combination with the 0