We recently reported that the photo-activated chlorine dioxide radical (ClO2 • ) gas acts as an efficient oxidizing agent for the C-H bond oxygenation reaction. This photo-activated ClO2 • oxidation method is applicable for oxidative surface modification of polymer materials, including chemically inactive PP. Furthermore, this surface modification method can be applied to complex structures because the activated gas can react inside the textile. In this study, the surface of PP NWFs was oxidized via a modification method using photo-activated ClO2 • gas. In addition, β-CD was supported on oxidized PP NWFs. Furthermore, we evaluated the loading and release properties of diclofenac sodium, non-steroidal anti-inflammatory drug (NSAID).