Since the two prediction models are based on completely different principles, the agreement increases the reliability of both models. COSMOtherm provided, on average, 0.26 (±0.27) and 0.24 (±0.23) higher log Kow and log Koa predictions, respectively, and 0.33 (±0.25) lower log Kaw values than the PP-LFERs. It is likely that the current version of COSMOtherm slightly overestimates the partitioning of PFAS from air to liquid phases, as reported in previous articles. Note that some predictions from the PP-LFERs presented here cannot be considered "fully predicted" because the solute descriptors used were calibrated with the experimental data for Kow and Kaw. Further comparison between PP-LFERs and COSMOtherm was performed for other solvent/water and solvent/air partition coefficients using the PP-LFER equations published in the literature (Figure ). Although the PP-LFER equations in the literature are often not calibrated with PFAS, the predictions of PP-LFERs and COSMOtherm agree within 1 log unit in most cases, similar to the results shown in Figure .