Unsurprisingly, the calculated barriers show a strong dependence on the distance the hydrogen atom has to travel during the reaction, as can be seen in Figure F. However, barriers vary significantly for a given translation, substantiating the need to use more complex system descriptions than just translation. The synthetic data, by construction, includes data at translations down to 0.3 Å and with barriers smaller than 20 kcal/mol, cases not covered in the trajectories, where small interatomic distances are disfavored and thus rare. Translations found in trajectories start from 0.7 Å, but the vast majority are larger than 1. Also, the translations are comparatively short, with an average distance of 1.2 Å. Examples of the lowest and highest barriers can be found in Figure .