Figure shows DLS characterisation of 5c1 (NI0.8NC0.2)-based nanogels after cross-linking. 5c1based nanogels could be cross-linked successfully, yielding larger sizes compared to 5a4-based nanogels when measured below the LCST (181 ± 4 nm vs 133 ± 9 nm). Cross-linking of 5c2based nanogels could not be achieved due to severe aggregation and precipitation. Hence, detailed morphological analysis was restricted to the two copolymers that could also be crosslinked successfully (5a4 and 5c1). Long-term stability of cross-linked nanogels made from these two block copolymers when incubated in PBS at 37 °C was demonstrated by DLS (Figure ).