Preparation of phase mixtures of TBZ salts proved to be a practical approach for further adjustment of the dissolution rate. For instance, 1:1 binary phase mixtures of HTBZ-SAC/HTBZ-HMA (Figure ), HTBZ-HFU/HTBZ-SAC (Figure ), HTBZ-HMA/HTBZ-HFU (Figure ), and HTBZ-HMA/HTBZ-HOX (Figure ) exhibited dissolution rates that fell between those of the respective purephase samples. This observation results from the different solubility rates for each salt of TBZ with two co-formers present in a mixture. Additionally, the pH value of the solution is affected by the increasing amount of the acid content. The overall solubility of the mixture is affected by the crystal structures of each component, the composition of the solution, and the interactions between the constituents. Further studies are needed to decipher the role of each of these effects.