based on the assigned stereochemistry of the major diastereomer of 3b. CSP-HPLC analysis confirmed that the 82% de starting material was converted with good fidelity to enantioenriched (82% ee) catenane 6. Crystals of a rac-6 suitable for SCXRD analysis were also obtained, allowing the structure of the product to be confirmed unambiguously (Figure ). Finally, we turned to the synthesis of a co-conformationally topologically chiral target.