Understanding the relevant conformational degrees of freedom causing bi-modality in the work distribution remains elusive Compound hp7 was previously investigated by Schöller et al. , who identified outliers in the work distribution and explored torsional degrees of freedom as a potential source. In this work, we also observed annealing trajectories with associated work values that would be considered outliers using the criteria employed by Schöller et al. (deviation of more than 3 σ from the mean) for both MM→NNP and NNP→MM switches of hp7. Figure shows the MM→NNP and NNP→MM work distribu- To investigate the origin of these outliers, we performed a 2-D torsion scan (see Figure )