Surprisingly, when bulky chemical functionalities are incorporated into gis framework, these bulky components act as stoppers, similar to those in macroscopic machines. Furthermore, gis-ZIF-1 exhibits exceptionally low Young's and shear moduli, representing it as a potential candidate for applications requiring energy absorption. Our findings demonstrate that ZIF nanomachines are indeed mechanical metamaterials, with their mechanical properties largely determined by the structure and connectivity of their rigid components, according to the work by Alavi et al. Notably, the ZIF nanomachines presented here enable efficient synergistic movements between rigid components through adjustable chemical functionalities. This capability may pave a way for advancements in properties interlinked with mechanical behavior, exhibiting the vast potential in the realm of nanotechnology, including soft robotics and digital data storage (see Figure ). We expect that such efforts provide a blueprint for design of solid-state nanomachines at the molecular scale.