The KMC simulation run time depends on the number of reactions that occur in the simulation and not on the total time observed in the simulation.This feature of KMC simulations makes the algorithm particularly suitable for low temperature extrapolation because at lower temperatures there are less reactions occuring in a given time. Meanwhile, MD simulations are not suitable for low temperature because their run time is proportional to the time observed in the simulation; therefore, only a few reactions can be observed at low temperatures in an MD simulation.