Phosphorus management is especially important in dairy farming, where large quantities of N-and P-rich dairy manure are generated and routinely used as fertilizer. The low N:P ratio of dairy manure does not match the nutrient requirements of most crops; this promotes the overapplication of manure and accumulation of P in soil. The nutrient content of manure varies by farm and season, but generally has an N:P ratio of ~6:1. When applied to fields to meet the nitrogen demand of corn (which requires an N:P ratio of 7:1), this leads to roughly 15% of the applied P being left unconsumed. Rain can mobilize excess soil P and deposit it in local waterways, representing a loss of valuable and non-renewable nutrients. P runoff into waterways also supports harmful algal blooms in lakes and other waterbodies, a process known as eutrophication. In addition to the severe environmental damage they cause in aquatic ecosystems, harmful algal blooms also have significant health and economic costs on the residents living around eutrophic waterbodies. For instance, it has been estimated that leaching one kg of phosphorus into waterways can lead to socioeconomic costs that reach 75 USD, due to the combined loss of recreational/tourism activities and to impacts on property values. Technologies that support more sustainable manure management practices have existed for decades. Anaerobic digestion (AD) systems process raw manure by feeding it to microorganisms that generate biogas, a mixture largely composed of CH4 and CO2. The primary benefit of AD treatment is the generation of methane as a renewable fuel that can be used for electricity generation, heating, or as a transportation fuel. The unconsumed material left over after AD treatment and solids separation (known as digestate) contains most of the nutrients from the raw manure and is typically applied as a liquid fertilizer. Critically, while AD reduces methane emissions from manure, it does not address the N:P imbalance. As a result, digestate application has the same potential for overapplication of P and eutrophication as manure application. One avenue for balancing nutrients in wastewater is biological nutrient recovery, typically using phosphate accumulating organisms (PAOs). Cyanobacteria have gained particular interest in the biological nutrient recovery space, as photosynthesis allows cyanobacteria cultivation to be a net consumer of CO2 and operate in inexpensive fermenters like open raceway ponds or bag photobioreactors (b-PBRs). In contrast to heterotrophic PAOs, autotrophic PAOs like cyanobacteria do not require a fixed carbon source, allowing them to be deployed in carbon-poor waste streams like anaerobic digestate without the need for an additional fermentable carbon source. Previous work has demonstrated that cyanobacteria can be grown using nutrient-rich waste streams such as digested dairy manure. The produced biomass can serve as an effective biofertilizer when combined with synthetic fertilizers resulting in similar crop yields, slower nutrient release (which reduces soil leaching), and a smaller carbon footprint when compared to using synthetic fertilizers alone. Furthermore, the use of biofertilizer can also enrich soils by increasing organic carbon content, decreasing soil erosion risk, and improving the health and diversity of microbial and fungal communities. Using modern genetic tools, cyanobacteria have been modified to produce fuels, feed additives, and commodity chemicals, enabling co-production of valueadded chemicals in a waste management process. While previous work has explored the development of cyanobacteria-driven nutrient recovery processes, the use of genetic engineering to improve process performance is less studied.