The data in both databases are converted to have unique molecular identifiers (InChI) for solvent and solute. The solid solubilities are reported in the units of the original data source such as mole fraction, g/kg, and mol/kg. They are also converted to molar units required for model comparison log10(mol solute /L solution ) (further referred to as log(mol/L)). Ideally, the density used for conversion of the units should be the density of the solute and solvent mixture. However, those densities are in most cases not available, and thus the density of the pure solvent is used. The distribution of the log(S) values in the CombiSolu-Exp database is added to the supporting information (Figure ) and compared to the distribution of the log(S) values in the AqueousSolu-Exp database. Duplicate entries are retained in both datasets to better analyze the effect of different experimental data sources and associated experimental uncertainties. For 12% of the duplicate data, the absolute deviation between log(S) data points is >0.2. The uncertainties in the experimental data are significant and affect the performance of the models, see supporting information (Figure ).