Atomically precise metal nanoclusters (NCs), renowned for their unique structures and molecule-like properties, have shown exceptional catalytic capabilities due to their quantum confinement effects and high density of active sites. Among these, [Au25(SR)18] -NCs have been particularly recognized for their significant electrocatalytic activities in both CO2 reduction and hydrogen evolution . The pioneering work by Kauffman et al. first highlighted [Au25(SR)18] -'s ability to efficiently reduce CO2 to CO with high selectivity and low overpotential at commercially viable current densities, establishing the potential of these nanoclusters in electrocatalysis. The bimetallic PtAu24(SR)18 NCs, explored by Kwak et al., demonstrated the remarkable catalytic activity for hydrogen production in HER, surpassing previously reported molecular catalysts and even outperforming traditional platinum catalysts, setting a new benchmark in the field.