Initially, the solubility of drugs was tested in various solvents to select the best solvent for thin film-hydration method. In our previous studies, depending upon the solubility of the drug, the most commonly used solvent is EtOH. Herein, most of the enlisted drugs were also soluble in ethanol (EtOH) with the exception of dasatinib, clofazimine and lapatinib for which mixture of EtOH/Acetonitrile (ACN) and methanol (MeOH) were used, respectively. All the information about solubility of drugs in organic solvents is presented in Table . The drug formulations were prepared by thin film hydration method as reported previously .