CURC is a natural compound which can be promising for photosensitization purposes and more specifically for PDT and LAC applications. However, its complex, and environmental driven, conformational equilibrium may alter its native photophysical properties. Here we report a non-adiabatic molecular dynamic study of the behaviour of enol CURC after excitation to the bright S1 state. After having properly benchmarked the chosen level of theory, achieving a good compromise between accuracy and the need of an extended sampling, we have shown that enol CURC may lead to ISC, albeit not in an ultrafast process and is characterized by a 3.4 ps rate determining step. ISC proceeds via the initial population of the high-laying T4 state and is followed by an ultrafast IC cascade in the triplet manifold. An equilibrium between S1 and the higher excited states, especially S2, and resulting in a population redistribution can also be evidenced.