Example images of 25 mol% PBd12-PEO11 GUVs in Figure show the separate DiO and PBd22-PEO14 -TMR channels as well as the merged image. The images of DiO and PBd22-PEO14 -TMR channels in other hybrid compositions can be found in the ESI. While both dyes are present in all GUVs, it is visually apparent that there are relative composition differences, where the DiO or PBd22-PEO14 -TMR probes are relatively brighter in individual GUVs, indicating the presence of lipid-rich (red arrows) and polymer-rich (blue arrows) GUVs, respectively.