Figure shows that DT released from the Brij micelle at pH 1.5 did gradually rather than all at once. For Brij 58 and Brij S20, respectively, more than 71 percent and 58 percent of the loaded medicines were released. Within 300 minutes, the majority of the DT release from Brij S20 micelles was seen. On the other hand, Brij 58 showed about 330 min to reach a steady state. The cumulative release % data were fitted into the Korsmeyer-Peppas model here the R 2 values were more than 0.98 in both cases as shown in figure and Therefore, as strong binding leads to low release, the aforementioned results are justified.