To improve cell adhesion and proliferation on polymer surfaces, many researchers modify the surface by altering mechanical properties and topography. Yet, one of the most utilised and facile methods for facilitating cell adhesion to polymer surfaces involves altering the surface energy via exposure to plasma gas. A primary example of this is the use of tissue culture plastic (TCP) in the majority of cell culture laboratories, which mainly consists of polystyrene treated with plasma gas which drastically improves cell adhesion. Depending on the gas used and time exposed, the surface can be modified to introduce new bonds such as COOH, COH, NH2, SH.