Integrating LLMs and advanced computational methods into the monoclonal antibody production process as described in the article can significantly enhance model accuracy, reduce development time, and optimize production strategies. By focusing on the areas highlighted in the quotations, the greatest improvements in speed and performance can be achieved. The article discusses the production of therapeutic glycoproteins in glycoengineered plants. To advance monoclonal antibody production through the incorporation of Large Language Model integrated problem solving, the following areas can be improved: