We tested the MD simulations of the three RNA-protein complexes using three traditional nonpolarizable force fields: Amber RNA force field OL3 with protein force fields ff14SB and ff19SB , the all-atom force field OPLS4 , the polarizable AMOEBA force field and the OPC3-pol polarizable water model with the ff19SB and OL3 force fields. The total simulation times for all systems were at least 1μs. It is possible to run reasonable RNA-protein complex simulations with any of the tested force fields and none of them outperforms the others in all cases. However, especially when running hundreds of ns-scale simulations with the polarizable force fields or water model, one should pay attention to the structural integrity of the complex. Overall, we recommend testing of different force field combinations to find a setup that works for both your system of interest and research question.