Finally, 4327 NPs in NAPROC-13 were unique when compared against the current version of COCONUT. This finding reveals the valuable work of correcting elucidated NP structures. Some of their structures and classifications are represented in Figure . In general, the values of the descriptors discussed so far highlight that about 75 % of the NPs in NAPROC-13 are within the values of the classical empirical drug-likeness rules, except for MW, with a Q3 of 502.52 (exceeding the rule by less than 1%).