The generated carbon monoxide serves as a crucial precursor in subsequent reactions, showcasing the seamless integration of our light-assisted process with synthetically valuable cross-coupling reactions. This integration was demonstrated through the successful execution of carbonylative Suzuki coupling, alkoxycarbonylation, and aminocarbonylation reactions using on-demand carbon monoxide directly from our automated photoreactor platform (Figure ). Carbonylation reactions hold particular significance due to the versatility imparted by the carbonyl functional group, a key constituent of numerous biologically active molecules and pharmaceuticals. Traditionally, achieving selective carbonylation reactions necessitates high pressures and temperatures. However, the reactions conducted in this study proved compatible with the continuous supply of carbon monoxide, requiring only low pressures and moderate temperatures. This underscores the potential of our carbon dioxide upgrading approach to facilitate efficient and sustainable synthesis routes for diverse carbonylation reactions.