Towards a framework for systematic evaluation of force field accuracy using Markov models. While comparing molecular simulations to experimental measurements does not require a Markov modeling framework, the use of MSMs for this purpose have several advantages. One is that robust and reproducible protocols now exist for featurization and unsupervised MSM construction that could used more systematically to more automatically analyze simulation trajectory data. Using VAMP, optimal tICA projections were identified, and these in turn clearly revealed mechanistic information about the chignolin folding landscape and relevant macroscopic intermediates.