UCB (C=∞) shows trends in node selection fractions similar to those of Random, differing fundamentally from the corresponding trends in node selection fractions in the Passerini reaction dataset, where the exploration term in UCB favored the selection of nodes near the goal node. Among the exploration-exploitation balanced policies, although the PI and EI node fraction trends are the most similar to those of UCB (C=∞), the performance of selecting nodes near the goal does not degrade substantially compared to that of Greedy.