The simulations were done using the CHARMM36 force field for lipids. Membrane models were simulated in TIP3P water models with a 12 Å nonbonded cutoff. Anisotropic pressure coupling was held consistent using the Langevin piston method at a pressure of 1 atm. Using the SETTLE algorithm to fix hydrogen bonds at the same length, the time step was at 2 fs. Temperature was controlled with Langevin thermostat at 310 K with 1 ps -1