In the ICFR, the oil in the cell mass is recovered by centrifugation after cellulosic pretreatment with the bagasse. Previously published biorefinery designs co-producing ethanol and biodiesel were envisioned to process oilcane with oil contents between 5 to 15 dw % to overcome trade-offs in capital investment that stem from the equipment necessary for ethanol and biodiesel production. The biorefinery configurations presented here are alternative designs based on our previous work that eliminate ethanol production in favor of microbial oil production.