As reported in our earlier work with the synthesis of boramidines , limited fluorescence tunability was observed with changes in the substitution of the pyridine ring. In our scope of borindolizines, we have demonstrated rapid scaffold modifications from enaminoester-based scaffolds (3a-3g) to biaryl scaffolds (3h-3o) under the same synthetic regime. Consequently, we observed long-range emission tunability in wavelengths between the boramidine (397 nm, 3.12 eV), ester (3a, 431 nm, 2.87 eV), heteroaryl (3c, 458 nm, 2.71 eV), and 4-tolyl (3h, 518 nm, 2.39 eV) substituted borindolizines -effectively spanning a 120 nm range from violet to the green regions (Scheme 1A). Furthermore, changing the electronics of the pendant aryl group through substituent changes results in a smaller change in emission wavelengths, offering a handle for fine-tunability of emission (Scheme 1B).