Exposure to high H2S levels can be hazardous for an individual's health. Excessive amount of H2S has been linked to a few illnesses, including ulcerative colitis, heart problems, and neurological diseases. Therefore, DT's release must be balanced and regulated. Moreover, shortly after it is formed, DT starts to break down and produces a variety of sulphide compounds, including tri-, di-, and cyclic disulfides. DT also reacts with non-polar chemical solvents and in high temperature it produces cyclic disulfides and ajoene . Therefore, a suitable carrier matrix is necessary to deliver ample amount of DT in the body which may increase its bioavailability. Additionally, a controlled release type discharge method is also needed to steadily supply DT without causing any undesired toxicity due to overdose that may happen because of burst release. Entrapping sensitive molecules in micelles is one method to prevent them from being broken down in the gastrointestinal system . Phytochemical delivery makes extensive use of a variety of biocompatible non-ionic polymers, including long chain fatty acids, polyethylene glycols, poloxamer, alkyl esters, alkyl polyglycerol ethers, sorbitan esters and brij for this purpose . Above their critical micelle concentration, these polymers can naturally develop nano-scale assemblies (from 1 to 200 nm) micelles . The 'corona,' an outside hydrophilic shell that affects in vivo pharmacokinetics, is attached to a central hydrophobic core in these assemblies. The core is in charge of preserving the solubility, release, entrapment, and stability of the entrapped molecules . The entrapped molecules are protected against deactivation, degradation by the liver and needless breakdown by a variety of in vivo stimuli by the core-shell structure of the micelle. Ergo, micelles are a potential option for DT's efficient administration because of their capacity for targeted drug release .