RDKit 58 , CDK and ASE 63 are three extensive libraries for performing computational chemistry, with RDKit and CDK focusing on analysis and post-processing, and ASE on performing atomistic simulations. They are mainly accessed via an API, but RDKit and ASE also offer a number of standalone programs. Finally, AQME 65 is a collection of workflows designed to automate various repetitive computational chemistry tasks. Despite the plethora of programs and libraries that are available, a complete single solution is not readily available. Many of the codes that are described above offer excellent support for either analysis or submission management, but none offers sufficient support for both for it to be used as a standalone tool. The user must still navigate multiple different programs in order to manage the complete pipeline. In particular, none of the tools that we have explored offer comprehensive support for large-scale computational screens, where the number of individual computations may reach the thousands, and in these cases the scientist is still expected to develop their own scripts. Many of the programs that offer a more complete set of tools may also be too expensive for a subset of researchers, or exist only as programming libraries, and cannot be used without the scientist having coding experience. To address this problem, we have developed Digichem, a complete computational management tool suitable for computational chemists of all skill-levels, but particularly directed at novice users. Digichem is designed to be the only program the user needs to interact with on the server (Figure ). It contains both a command-line and pseudo-graphical interface, the latter powered by the Urwid library, and supports computational screens of unlimited size. Here, we describe this program and its operation in detail.