Notice that the presence of a capping agent can be either beneficial or detrimental. On the beneficial side, it can stabilize the sheets, improve the dispersion in different solvents or facilitate their functionalization with active functional groups. However, its presence can be detrimental for applications involving the accessibility of species to the surface of the nanosheet since it can be hindered. In this scenario and focusing on MnPS 3 as a prototype MPX 3 material, we have optimized the previously reported chemical intercalation-exfoliation process to obtain aqueous suspensions of high-quality layers with and without the use of different capping agents (see Scheme. 1). Herein we present a detailed study of the stability of the suspensions and the quality of the resulting layers. In a further step, we have proved how, by means of choosing an optimum capping agent, it is possible to obtain a compromise between suspension stability and high accessibility to the MnPS 3 surface, fostering its applicability in fields like electrocatalysis in which the solution/solid interface is key.