Natural products have demonstrated their key role in developing new drugs, materials, nutraceuticals, pesticides, and insecticides, which justify their study . Nowadays it is possible to establish structureproperties relationships using bioinformatics and chemoinformatics methodologies . To achieve this goal, it is necessary to condense, organize, and curate the databases. Recent efforts in Latin America have been developed on the construction of natural products databases that have contributed to the understanding of Latin American traditional medicine, and to accelerate the rational use of natural products in this geographical region . Particularly in Mexico, there are two compound databases that are mainly focused on the natural products identified in the central zone of Mexico. However, there are no reports of databases from the most biodiverse regions in this country.