1 H NMR spectra were recorded using a Bruker Avance 300 spectrometer in D2O at 298 K with a number of scans of 256 and a relaxation delay of 10 s. Chemical shifts are reported in parts per million (δ ppm) with the 1 H NMR solvent peak (D2O: δ = 4.79 ppm) as reference. Analysis of spectra was conducted using Bruker's TopSpin software.