Ebola disease is a hemorrhagic fever caused by the Ebola virus that has a 90% death rate. The 2014 West Africa outbreak was characterized by fever, tiredness, vomiting, diarrhea, and anorexia; acute electrolyte imbalance was a deadly factor. Clinical research on Ebola virus disease remains challenging, and statistical analysis of hematological and biochemical anomalies is limited. The electrolyte imbalance mechanism underlying Ebola sickness is critical for halting the epidemic's progress and saving lives.