Artificial anion transporters present an attractive field of research with possible applications as either therapeutics for channelopathies or anticancer agents. In recent years, a growing number of researchers started to investigate new anion transporters. For the screening of promising compounds as potential anionophores artificial model systems are used, in particular large unilamellar vesicles (LUVs, also referred to as liposomes) made of phospholipids to mimic cell membranes.