Based on these benchmarking results, our top recommendations for calculat-ing metalloenzyme BHs and REs are SOS0-PBE0-2-D3(BJ)/def2-TZVPP and revDOD-PBEP86-D4/def2-TZVPP. SOS0-PBE0-2-D3(BJ) performs well across the range of metalloenzymes tested here, and we have previously shown its accuracy for organic enzymes as well. Double hybrid DFAs are more reliable than hybrids across the board, although the best hybrid functionals still perform well. With all DFAs, we strongly recommend the use of a dispersion correction. For copper-dependent enzymes specifically, a double hybrid DFA with only a small amount of MP2 correlation is the most reliable option, so we also recommend PBE0-DH for these. Acknowledging that double hybrids can be prohibitively expensive, we also recommend the hybrid functionals ωB97M-V and ωB97X-V. MPW1B95-D3(BJ) also performs well, but the LibXC implementation makes it slower than other hybrid functionals directly implemented in ORCA. We do note, however, that functionals that are good for energetics are not always the best for geometries. A test of small organometallic complexes have shown that ωB97M-D3(BJ) and ωB97M-D4 perform similarly to B3LYP-D3(BJ) for geometry optimizations, while B97M-V is slightly better, 10 but without further testing we can only definitively recommend these functionals for single point energy calculations.