99% yield) with respect to the standard transamination process (i.e. 69% yield when run without membrane-assisted extraction). Additionnally, by demonstrating the intensified asymmetric synthesis of the R-sitagliptin drug, Yang et al. successfully expanded the applicability of such synergistic coupling between transamination and membrane-assisted product separation. In this case, transamination was conducted in aqueous medium (pH = 9) and PDMS was used as membrane contactor for the solvent extraction. In all these examples, the use of membrane operations offers avenues to intensify the synthesis process.