was low for all peptides. Fitting the binding data with the Langmuir mono-site binding model resulted in the binding parameters given in Table . Overall, the polymers exhibited stronger affinity for the peptides in the acetonitrile rich medium with saturation capacities (Bmax) for the peptide complements reaching 2.5-3 µmol/g and for the noncomplements ca 1 µmol/g for the pYY-and YpY-MIPs and 0.5 µmol/g for the pYpY MIP (Table ). The pronounced specificities were accompanied by dissociation constants KD in the single digit µM range.