A. baumannii is a Gram-negative bacteria causing health careassociated infections resistant to multiple antibiotics . For instance, A. baumannii is a leading cause of nosocomial infections, particularly in intensive care units. It can cause pneumonia, bloodstream, urinary tract, and surgical site infections associated with high mortality rates. The ability of A. baumannii for environmental persistence and for dissemination of antibiotic-resistance genes is a global concern . A. baumannii has demonstrated resistance to a wide range of antimicrobial agents, including carbapenems, which are considered the last line of defense against multidrug-resistant bacteria . The increasing emergence of pandrug resistant A. baumannii strains further limits treatment options constituting an emerging target aspect for new drug discovery . Identification of novel antibiotics against A. baumannii is crucial for world wide healthcare .