A similar trend as described above for P1 can be observed in the samples comprising P2 and IND (Supporting Information Figure ). At 80wt% drug, signals 1 and 2 are clearly observable, while at 75wt% signal 1 disappears. Signal 2, on the other hand, remains visible as a shoulder of signal 4. With a further decrease in the drug loading, neither signal 1 nor 2 are observed in the spectra.