Natural products, particularly those derived from medicinal plants, have garnered significant attention due to their diverse bioactive compounds, lower toxicity, and potential for novel mechanisms of action. One such plant is Ginger (Zingiber officinale), a widely recognized herbaceous plant, has been utilized for centuries both as a spice and in traditional medicine. Its rhizome is commonly used as a natural remedy to relieve ailments such as pain, nausea, and vomiting . Numerous randomized clinical trials have explored ginger's antiemetic properties in contexts like motion sickness, pregnancy, and post-anesthesia . To date, researchers have identified and isolated more than 100 compounds from ginger . Its nonvolatile components include gingerols, shogaols, and paradols, with gingerols and shogaols being particularly abundant . Among them, 6-gingerol (Figure . 1) stands out for its anti-nausea, anti-inflammatory, antioxidant, as well as anticancer activities .