The interplay between chemical transport and reaction kinetics is fundamental in immune responses. Reaction rates of immune mediators are highly dependent on their timely transport to necessary locations. Abnormal coupling can result in delayed or hyperactive responses, impacting the system's equilibrium . The rate of cytokine binding to receptors, for example, is influenced by both the concentration of cytokines and the rate of cytokine-receptor interactions . This coupling ensures a localized and timely immune response, critical for effective pathogen clearance and tissue repair.