If we now take stock of all the results from this analytical panel, and put them into perspective with what is commonly in use in the community, starting with the recommendation from Tian et al., we can first state that our observation are very much in line with theirs. As these authors point out, SEC is the main technique for monitoring changes in molar mass distribution as polymer degradation proceeds. NMR and HPLC are used to identify the intermediates and end products, respectively, that result from this degradation. MALDI-TOF, on the other hand, is primarily used to identify the end groups formed. However, contrary to the authors' conclusions, the latter does not appear to be suitable for the measurement of average molar masses, since from our observations in the present study, but also when reading the bibliography dedicated to this technique, it appears that MALDI favors low masses to the detriment of high masses. This results in a biased representation of the populations, and it can therefore neither be used quantitatively, nor even really allow the degree of polymerization of the polymer to be calculated at a given time. Finally, our study has interestingly also shown that infrared spectroscopy can not only identify broken and formed bonds, but also quantify the degree of polymer degradation, with different minimum detection levels depending on the peaks used to identify the species involved. The advantages and disadvantages, as well as the detection limits that we were able to determine for these 5 analytical methods are summarized in order to offer a guide to the selection of the most appropriate according to the anticipated depolymerization/degradation yield as well as other parameters such as the complexity of the reaction medium or the need for high throughput.