Another broad scenario where the full extent of pseudorotations could become apparent concerns molecular confinement. Molecular confinement describes an extremely diverse set of situations as wide ranging as the industrially important zeolite catalysts to the reaction sites of enzymes. A common feature in all cases is that the orientation of a guest molecule within the host has a frame of reference where molecular rotation is suppressed either partially or completely. Consequently, an orientation permutation via a polytopal rearrangement (pseudorotation) may manifest chemically. An analogous volume-conserving, concerted stereoisomerisation phenomenon precedent exists and is well studied, that of the torsion-based Hula-twist mechanism. On the theme of a "frame of reference", a strong external electric field can also provide this. For the low coordination numbers, molecules featuring the two-coordinate bent (A-2) and three-coordinate trigonal pyramidal (TPY-3) polytope configurations will, in general, have an electric dipole associated with them. Such molecular dipoles will respond to a strong external electric field. The maser -the forerunner to the now ubiquitous laser -was first realised in 1955 with the ammonia maser and exploited a polytopal rearrangement within an external electric field polarised molecular beam. Our transoid B(F)OB(F)-porphyrin systems also exhibited a significant dipole reversal upon thermally driven akamptisomerisation. Additionally, experimental evidence of bond-angle reflection has been presented for thermal effects on dipole moments and associated optical-configuration parameters in poly(dimethylsiloxane).