In order to assess the generalizability of the descriptor identified by SISSO, we verified the predictions of ? @A given by Eq. or Mn +4 cations can be stabilized in perovskites, the stabilization of certain oxidation states of B' species such as Cu +3 is challenging. This motivated us to consider the substituted Mnbased perovskites AMn(1-x)CuxO3. We note that no substituted perovskite was considered in the training set. Besides, the elements Cu, Ni, and Zn were not present in any material of the training set. These additional materials were synthesized by solution combustion synthesis and they were subjected to the same characterization methods and catalytic experiment as those used for the 13 ABO3 training set materials. Experimental details are provided in ESI. The values of the primary features for these 19 materials are provided in the dataset.xls supplementary file. In order to evaluate the model of Eq. 3 for AMn(1-x)B'xO3 materials, we took RS , and TR , as the composition average of the elemental properties of Mn and B' elements following RS , = 1 -7 RS JK + 7RS Oo (Eq. 4) and TR , = 1 -7 TR JK + 7TR Oo . (Eq. 5)