In this manuscript, we aim to explore the role of OSS in computational proteomics and its implications for the development of FAIR research software. We will discuss the benefits and challenges of OSS in proteomics, the role of OSS in the development of FAIR research software, and the importance of distribution, licensing, and citation of software in computational proteomics. We will also explore how other omics fields deal with OSS and FAIR software and how these experiences can inform the development of proteomics software. Our goal is to present a vision for a future where OSS and FAIR software are encouraged and supported in the proteomics community.