In the era of high-performance computing, the scientific paradigm is shifting towards efficient exploitation of computational power. Therefore, the adaptable and efficient scientific software for such computing architectures is of great interest when implementing new robust theoretical models. In this spirit, the MiMIC framework has been developed to per-form electrostatic embedding multiscale molecular dynamics simulations in a highly flexible way. The current MiMiC implementation enables QM/MM simulations with electrostatic embedding and exploits the efficient parallelization of routines involving real-space grids for calculations with plane waves (PWs) within the CPMD. Though originally formulated for treating periodic systems, PW basis sets can also be applied to molecules through super-cell formalism. This approach is compatible with the KS-DFT method, thus allowing the use of PWs for heterogeneous molecular systems in combination with explicit MM models. Exploiting the massively parallel computational methods involved in such calculations enables QM/MM simulations of extended systems from solid-state materials to complex biomolecular structures and also provides a highly suitable basis for an extension to QM/MM models with polarizable potentials.