Recently, we presented a simple and consisted fragmentation scheme that combines the MFCC method with a two-body expansion, termed MFCC-MBE(2) . To ensure that only calculations for the (capped) fragments, caps, and combinations thereof are required, this scheme builds on the MOBE instead of the more general schemes . The MFCC-MBE(2) method first approximates the total energy by the MFCC scheme, then all fragment-fragment interaction energies are calculated and the sum is added on top of the total energy. To correct for double counting, all occurring fragment-cap and capcap interactions are also calculated and enter the equation with a negative sign for the fragment-cap term and with a positive sign for the cap-cap term, i.e.,