Alternatively, MR analysis in the solid state requires transfer of the product to a rotor, which is then spun at high speed at the magic angle for spectroscopic analysis. Schiffmann and coworkers have assembled a miniaturized milling apparatus that is compatible with a magic-angle spinning solid-state MR instrument. This is a powerful approach to the mechanochemistry analysis problem, but it is not a general solution that can be translated to routine practise by a wide range of laboratories. The time domain relaxation correlation approach, T1-T2* permits analysis of static samples and eliminates the need for material transfer in lab scale mechanochemistry, with all the attendant benefits. In this work we employ synthesis of MOFs as test examples for this method. Specifically, the milling synthesis of the well-known material Zn-MOF-74 (also known as CPO- ) is monitored by T1-T2* relaxation correlation analysis, with special attention to the formation of an intermediate and evident colour change. We then successfully demonstrate the mechanosynthesis and this MR analysis of the zeolitic imidazolate framework ZIF-8 within a reaction vessel that is MR compatible. The nature of the information provided by relaxation correlation measurements makes these methods well-suited to following the progress of a reaction, but less well suited to a mechanistic interpretation of a reaction. Following the progress of mechanochemistry reactions with T1-T2* measurement with desktop MR instrumentation is our ultimate goal.