In addition, drug design to teach protein-ligand docking to undergraduates. Students have an increased appreciation of how chemical principles are applied to the drug discovery-development process . Finally, Rosetta software, a protein design tool, to address the challenge of improving the success rate of current computational methods for the de novo design of self-assembling protein complexes . Their research aimed to estimate the effect of point mutations at a particular position in a protein, through which students learned how to design computational experiments, maintain and analyze large amounts of data in collaboration, and develop scientific hypotheses from a fully remote environment. These studies demonstrated the advantage of incorporating molecular modeling in courses to enhance student learning.