The analogues 55-60 were prepared according to Scheme 6. The carboxylic acids of derivatives 19, 30, 33, and 36 were coupled with dimethylamine hydrochloride in the presence of HATU and DIPEA to yield the respective dimethylamides 55-58. Analogues 59 and 60 were prepared from 2-chlorophenylacetic acid 99, which was coupled with methyl benzoate (100) in the presence of LiHMDS to obtain 2-chlorobenzyl phenyl ketone 101. Bromination with NBS yielded the α-bromo ketone 102, which was converted to the ester 104 through nucleophilic substitution by monomethyl malonic acid 103. The ester 104 was then cyclized to oxazole 105 using NH4OAc in acetic acid. Saponification of the methyl ester with LiOH yielded 2-oxazolylacetic acid 59, which was subsequently coupled with dimethylamine hydrochloride in the presence of HATU and DIPEA to yield the dimethylacetamide 60.