After understanding the concept behind the FP-score classification for binding site residues on Holo-complex scenario. We ran a static FMOPhore scanning in an apostructure scenario for each system, (apo binding site conformation). The probes library is used to identify how the probes will bind to the binding site residues, and we evaluated the interaction energy and accessibility of the probes versus the residues using the FPscore quadrant matrix. Here we provide the output of two examples out of the sixteen systems, (The FMOPhore apo-structure scanning for the fourteen other systems are reported in the supplementary files 4.).