I hypothesize that blocking the binding site of this protein could prevent the HpaA adhesion protein interaction with the epithelial cells. I have used computational tools to find the interaction of antibodies binding to this protein. Based on our docking results, I have found that antibody 1IL1 strongly binds to the adhesin protein. This work will pave the way to develop novel monoclonal antibodies to target H. pylori and prevent gastric cancer.