Cefmenoxime (Figure and) had 6 major ligand interactions with NSP15, the shortest distance of which was 2.73 with the residue Lys290. Cefotiam (Figure and) had 4 major ligand interactions with NSP15, the shortest distance of which was 2.693 with the residue Leu246. Finally, ceforanide (Figure and) had 2 major ligand interactions with NSP15, the shortest distance of which was 2.70 with the residue Lys290. Figure shows the measures though MD distances between the NZ atom of LYZ290 of protein with the geometric center of these compounds. One can see that these distances pretty stable during MD simulations. ).