In the meta-dynamics search a molecular dynamics (MD) simulation is performed using a GFN2-xTB energy function that allows for bond formation and dissociation. The energy function is augmented by a biasing potential that rewards changes in the molecular structure. Our main question is whether this approach tends to produce molecules that are connected by low barriers. In addition to the usual MD parameters (time-step, length of simulation, temperature etc.), parameters describing the additional biasing potential must be specified. The biasing potential has the form [9]