That's what Table shows about the EEEV virus P protein: ARF7 effector protein C-terminal, BAR, Ephrin RBD, Granulins, MHD1, Sema, TLC, Transient receptor ion channel, Ionotropic glutamate receptor, Voltage-dependent calcium channel alpha-2. ARF7 effector protein and BAR are protein domains that are associated with the modification of membrane properties and curvature. Protein domains such as Ephrin RBD, MHD1, Sema, Granulins, Ionotropic glutamate receptor, and TLC are linked to the induction of neuronal growth, thereby interfering with synaptic growth and remodeling. The EEEV virus P protein disrupts synaptic growth and remodeling, or synaptic guidance, by impairing the function of synaptic Ca2+ channels, specifically the transient receptor ion channel and transient receptor ion channel, which are Ca2+ channel-related domains. The EEEV virus P protein generates a synaptic depolarization potential or hyperpolarization potential that either increases or decreases the excitability of postsynaptic nerves.