The SARS-CoV-2 Omicron S trimer model coded by the 7tnw.pdb crystallography file (Research Collaboratory for Structural Bioinformatics, RCSB, Protein Data Bank PDB ID) of the wild-type (without the PP stabilizing mutations) all-down S prefusion state was employed here. The 2021 isolate earliest wildtype SARS-COV-2 6xr8 model and the 7to4 Omicron one-up fusioncompetent model, were used for comparison.