Our experiments and simulations indicate that effectively incorporating electronic polarization via charge scaling in the prosECCo75 model provides results for cation-π interactions involving tetramethylammonium and pyridine that are in closer agreement with neutron scattering data compared to results obtained using the original CHARMM36 force field. prosECCo75 yields a stronger face-on interaction (compared to CHARMM36) of TMA binding to the aromatic ring. This is consistent with the expected geometry of the cation-π interaction. By reducing the net charge of the ion, ECC appears to lower its hydration penalty enough to facilitate a more pronounced interaction with the aromatic π-system in water, which also removes the pyridine aggregation artifact and the resulting low solubility resulting from the use of CHARMM36.