For a better interpretation and categorization of the simulation results, we apply the mean-field theory (Section 3) for the very same systems. Minimization of the Gibbs free energy of the system provides the effective volume of the polymer in the thermodynamic equilibrium with the salt reservoir, or equivalently the effective radius R pol if a spherical geometry is assumed. The polymers' effective radii in the thermodynamic equilibrium are depicted in Figure ) for an uncharged, weakly charged, and highly charged polymer chain, respectively. The results will not change significantly if a mean volume is used instead of the equilibrium volume. The theory matches the simulation results almost quantitatively when the effective radius (Figure )) and the radius of gyration, (Figure )) are compared. The theory correctly predicts salting-out power of anions and its concentration dependence for the uncharged polymer. In the cases of weakly and highly charged polymer chains, the location of the isospheric points matches the simulation data very well. Below the isospheric point, the salting-out power of anions forms the reverse series, while above the direct series is obeyed, which is in agreement with both the simulations and the experimental data.