We believe the theoretical framework developed here will allow for better understanding of mechanochemical principles as well as advance the exploration of using mechanochemistry to influence chemical synthesis routes and unlock new and/or exotic reactions typically unavailable to purely thermal chemistry. While we utilize a cost function that equally weights the cost of generating thermal and mechanical energy and limiting a constant total energy, this cost function can easily be replaced to account for a variety of methodologies to induce strain and thermodynamic conditions of the system, as well as 'costs' other than thermal/mechanical energy creation.