Aqueous solubility is a fundamental property essential for investigating and applying chemical compounds across various scientific disciplines, including chemistry and biology. Being able to dissolve a chemical substance plays a crucial role, e.g., in designing novel drugs, as the solubility has a high impact on the bioavailability of drugs and their distribution. In materials sciences, the solubility of chemicals has an effect on how materials are built and makes the difference in how active functional components are applied. While the solubility of commercially available building blocks is usually known at least for a few solvents, the investigation of newly designed and synthesized compounds needs the determination of the compounds' solubility. The measurement of solubility can be done by different methods, e.g. using HPLC techniques 2 , or gravimetrically .