The water within the model exhibits slower dynamics than it would in bulk solution. Whereas the expected diffusion coefficient for the TIP3 water model is 6 x 10 -5 cm 2 /s , we find that water diffusion within the confines of the cell wall is at least an order of magnitude slower (Figure ). Slower water dynamics compared to bulk with a similar order of magnitude difference have been observed previously through quasielastic neutron scattering measurements .