The structure integrity of 2%Fc12-PF6/MO and 2%Fc12-PF6/MO/GOx lipid cubic phases in excess PB condition were examined using SAXS (see Figure ). All samples exhibited the characteristic patterns of a Pn3m cubic phase. First, the SAXS patterns between MO with and without the presence of 2%Fc12-PF6 were compared. In the presence of Fc12-PF6, the Bragg peaks of MO slightly shift towards high-q region by 0.03 Å. However, upon hosting GOx the shrinking effect caused by Fc12-PF6 was less pronounced and the lattice dimension of 2%Fc12-PF6/MO/GOx reverted to algin with that of MO. As shown in Figure , a linear response to glucose was observed within the range 2-18 mM.