Up to this point, a unified road map for nucleation and growth mechanisms was derived by analyzing individual reports considering supersaturation conditions. We have also shown how general trends extracted from literature follow the proposed unified nucleation and growth map. It is now necessary to understand if the molar ratio is also determining the final shape and size of the ZIF-8 particles obtained, or if other synthetic variables have an impact on it. Molar ratio as predictor of ZIF-8 particles features If nominal concentrations (upon mixing) are considered instead of molar ratios, as shown in Figure , the existence of regions for methanol-and water-based synthesis becomes clear.