Trace metal analysis has been performed using inductively-coupled plasma mass spectrometry (ICP-MS). Unfortunately, ICP-MS is a highly specialized, costly method for analyzing palladium. The instrument is large and expensive, requires highly skilled experimentalists, a long calibration time upon starting, and expensive materials to maintain operation. Additionally, ICP-MS often becomes the bottle neck of the entire API purification process because scavenger screenings are high throughput while ICP-MS is low throughput, thus slowing the process.