The re-use of samples available in the Molecule Archive is supported by quality assurance measures, framework agreements, consulting, and support in handling of the reuse. For quality assurance, the registered samples are checked for purity and identity. The registration of the materials is not completed until the substances are physically available at the Molecule Archive and their identity and purity are checked. Compared to the sharing of data which can be managed by suitable licenses, the sharing of material needs material transfer agreements that clarify the role and rights of materials' providers, materials' re-users, and the Molecule Archive. The Molecule Archive supports the re-use of samples under a legal framework by providing a standardized material transfer agreement that was agreed on by KIT with different exemplarily chosen universities and published as a reference for further collaborators. Further, the Molecule Archive organizes the communication between the participating scientists as needed.