Table presents the amount of waste generated during the reaction, CAL-B filtration, and purification, as well as product purification and precipitation. Obtained results indicate that bulk polycondensation leads to lower waste generation per unit mass of the product compared to polycondensation carried out in diphenyl ether. The E-factor for the bulk process is approximately three times lower than that of the solvent-based process Based on the 1 H NMR signals characteristic for hard and soft segments, real segmental composition with number averaged molecular weight (Mn) were calculated according to the method described in Supporting Information and presented in Table . As evidenced by Table , the final compositions of PBA-DLA copolymers are comparable to the initial values. In both cases, there is a greater content of soft segments, which may be due to the removal of BDO when the high vacuum is applied. Since the reaction is performed with stoichiometric quantities, the absence of BDO leads to lower hard segment content. The rest of the reagents have higher boiling points, including DLD which due to its long aliphatic chain, is difficult to evaporate under high vacuum conditions.