These advancements would solidify the role of PythiaCHEM as a comprehensive and stateof-the-art platform for data-driven predictive ML models in various domains, offering both beginners and experts a powerful tool for their research and analysis needs. PythiaCHEM represents a significant step forward in the application of ML techniques in the field of chemistry. It embodies our belief that a user-friendly, flexible, and interpretable toolkit can foster a broader adoption and deeper understanding of ML.