similar lowest-energy geometries to SA within 2 kcal/mol, and misses four of them within 5 kcal/mol. Nevertheless, it provides additional structures that were not found in the SA search. Ditto for the GAFF force field, except for some very low energies that are not recovered. For the trans GPGG, the very low region is more sparse and a structure at 0.05 kcal/mol is missed with AMOEBA, as is another one close to 5 kcal/mol that was spotted with GAFF. Overall, this demonstrates that GA-sampled structures are indeed relevant for the low-energy resolution of the ab initio PES. Should the results not be satisfactory, there is always the possibility of running additional GAs and/or performing a higher number of re-optimizations.