Due to the dynamic nature of AMR and the growing requirement for up-to-date and harmonised surveillance data, WBE could be an appropriate community-wide estimation tool for providing complimentary information to GLASS. Applying WBE for AA usage could not only allow monitoring of local to international trends of AAs, allowing spatial and temporals to be established; but could provide baselines for community AA usage and assess effectiveness of intervention strategies. Thereby, offering potential evidence and support for AMR policy decisions. The combined analysis of parent compound and metabolite in wastewater could also give information about community compliance to AAs as well as incidents of pharmaceuticals being directly disposed of into the sewage system .