Since no human MATE1 protein structures solved, the AlphaFold 38 model of human MATE1 was used as a template of docking simulations. The model (AF-Q96FL8-F1-model_v4.pdb) was downloaded and processed for docking by assigning bond orders, adding hydrogen atoms and optimization of hydrogen atom positions, followed by optimization of hydrogen bond and whole complex energy minimization using the protein preparation wizard of Schrodinger Suite 2021-2 .