The redox properties of the NCP systems were determined employing a theoretical method based on Warshel's theory of vertical energy gap fluctuations and the general assumption of Marcus Theory for electron transfer reactions while also taking deviations from Marcus theory into consideration. This approach has been extensively employed for the investigation of chemical and biological systems, 59-69 including the determination of the redox properties of bare DNA fragments in biologically relevant conditions. Since this method has already been described in detail previously, only a brief overview will be presented here.