Figure computes the individual steps needed for passive permeation, from adsorption, crossing, to extraction back into aqueous solution. However, the units are clearly different, and it can be unclear when integrating Eq. 4 how to handle these mixed units to determine permeability coefficients. By reweighting our free energy profiles, we can place both sets of calculations into the same context, using the joint probability within our REUS calculations (Fig. ) to apply Bayes law (Eq. 6) to binned state probabilities derived from the free energy profile in Fig. . The resulting reweighted free energy profile (Fig. ) can be plotted on the same reaction coordinate as the interleaflet exchange process, resulting in Fig. .