Following the procedure that has been used in several previous papers, we used hybrid degeneracy-corrected second-order simple perturbation theory 122-125 (HDCPT2) to determine specific-reaction-parameterized (SRP) scale factors for each of the two possible transition structure conformers of this specific reaction (see Computational Details) while retaining standard scale factors for reactants. The resulting scale factors are smaller than the standard scale factor and result in a lower barrier on the ∆V G a curve and thus higher rate constants. As shown in Figure , the M08-HX CVT/SCT prediction is significantly improved when the SRP scale factors are applied to the transition structure conformers.