The seminal publication by Anastas and Warner in 1998 became the starting point for an impressive green chemistry movement within the organic synthesis community, and provided a blueprint for the coming generation of sustainable chemical processes. Guided by these twelve green chemistry principles, chemists around the world have since then pursued the design of atomeconomical, energy efficient and selective synthetic protocols that can allow for the environmentally benign production of value chemicals. Despite the major progress in this area over the past decades, new innovations relating to sustainable chemical processes are still as relevant today as they were back then. Currently, the chemical industry sector is responsible for 7% of the global anthropogenic greenhouse gas emissions, and moreover, it is the industrial sector with the highest final energy consumption, which emphasizes the need and the potential future benefits of broadly adopting greener and more efficient chemical processes in the large-scale manufacturing of chemicals.