Altogether, already the embedded db-MBE(2) clearly improves compared to the eb-MBE(2) and eb-MBE(3), which both do not provide sufficient accuracy for the relative interaction energies. The db-MBE( ) is able to reproduce the ordering of the isomers as well as their relative energies accurately. Previously, such an accuracy for this test case was only reached with an eb-MBE based on larger, overlapping fragments . It is noteworthy that with FDE-ft embedding, excellent agreement is also reached for the total interaction energies, for which the mean and maximum errors are as low as 0.6 kJ/mol and 1.3 kJ/mol, respectively.