Importantly, while the exascale era offers exciting prospects for quantum mechanical simulations, it also demands a cohesive effort from the scientific community to overcome the associated challenges. Collaborative initiatives, such as those driven by global research collaborations and industry partnerships, will be vital in shaping the future of computational chemistry and materials science. By embracing energy-efficient computing, stronger collaboration between academia and industry, and prioritizing the development of standardized software tools (e.g. languages, compilers, debuggers, libraries), we can ensure that exascale computing delivers on its promise as a cornerstone of scientific innovation, enabling us to take on grand challenges and push the boundaries of our understanding of the quantum world.