Unless otherwise indicated, all reactions were carried out under nitrogen atmosphere by using standard Schlenk or glovebox techniques in oven-dried glassware with magnetic stirring. Reagents were purchased and used as obtained from the suppliers. Solvents were obtained using a solvent purification system with an aluminum oxide column (Innovative Technologies). Flash chromatography was performed with Silicycle silica gel 60 (0.040-0.063 μm grade). Analytical thin layer chromatography was performed with commercial glass plates coated with 0.25 mm silica gel (E. Merck, Kieselgel 60 F254). Compounds were either visualized under UV-light at 254 nm or by dipping the plates in an aqueous potassium permanganate solution followed by heating. NMR spectra were recorded on a Bruker Avance 400 spectrometer with a BBFOz ATMA probe. The peaks were internally referenced to residual non-deuterated chloroform in CDCl3 ). The enantiomeric ratio value was determined on an Agilent or Shimadzu HPLC using CHIRALPAK column with hexane and 2-propanol as eluent. Optical rotations were measured on a Polartronic M polarimeter using a 0.5 cm cell with a Na 589 nm filter. X-ray analysis was performed by Dr. R. Scopelliti and Dr. F.Fadaei Tirani at the EPF Lausanne. Data were collected using a XtaLAB Synergy R, DW system, HyPix-Arc 150 diffractometer operating at T= 140.00(10)K.