Consequently, in such a case, the twinned crystal pattern coincides with one of the single crystals in the diffraction spot positions, but with a different intensity distribution. The presence of merohedral twinning was unambiguously excluded, as the intensity distribution of the experimental diffraction data is like the theoretical distribution expected for a non-centrosymmetric single crystal (Figure ). The crystal structures were solved to atomic resolution (Tables ) and crystallized in the hexagonal space group P622 with nearly isomorphous cell dimensions. The powder X-ray diffraction (PXRD) measurements of the crystals formed after 48h of heating indicated the homogeneity of the bulk (Figure ). The simulated PXRD spectrum of the SCRD analysis matches well with the experimental PXRD data. The space group P622 is a Sohoncke space group, thus indicating the presence of chiral molecular packings. Two types of continuous channels run parallel to the c-axis, having hexagonal and trigonal geometry, respectively. The hexagonal channels are formed by two concentric sets of spirals with opposite handiness. The handiness of the helicoids composing the external wall of the hexagonal channels is consistent with the helicity of the trigonal channels. The MOFs have chiral coordination nodes with an octahedral geometry (Figure ). Four pyridines are coordinated to the bivalent copper cation and arranged in a propeller-type fashion, with bond distances between Cu and N of 2.024 Å and 2.028 Å, which matches the distances reported in the literature for analogue complexes. Each pyridine belongs to a different ligand molecule. Chlorine counter anions are observed in the axial positions of the coordination node (Cu-Cl distance of 2.86 Å). Crystals with opposite chirality were observed and no chiral materials were used for their preparation. The crystals' packing is analogous to morphologically different MOFs previously reported by our group. The elemental composition obtained from the SEM-EDS of these crystals supports the presence of chlorine (Figure ) and solvents as confirmed by elemental analysis and TGA measurements (Table , Figure ).