In this paper, we focus on lipid models which remain yet to be updated to fully take advantage of the new interaction matrix available in Martini 3.0.0 . Notably, their CG representations have remained mostly conserved since the inception of the FF and do not allow to differentiate between some of the lipids. This is the case, e.g., of phosphatidylcholine (PC) lipids DLPC and DMPC, respectively including 12 and 14 carbons per "tail" and currently represented by identical CG models (Fig. ), while their phosphate-tophosphate bilayer thickness (Dʜʜ) differ by ~15% at room temperature . The exclusive usage of big beads for modeling the fatty acids, which are designed to represent 4 heavy atoms and their associated hydrogens, does not provide enough resolution to differentiate between the two lipids. Further refining the CG representation of the models, in principle, will allow to further enhance thermodynamic properties of lipids and lipid mixtures in Martini simulations . New experimental measurements have also become available recently for lipids containing polyunsaturated fatty acids (PUFA) and should be considered for guiding the refinement of their respective models (e.g. Dʜʜ thickness for SDPC and PDPC) .