To do so, we calculated the correlation between score and RMSD for all protein-ligand complexes in the PDBbind Core set. Table gives the average and median Pearson correlation values between score and ligand RMSD taken over the entire PDBbind Core set for all scoring functions. For all scoring function families, increasing the cutoff distance from 4 Å to 15 Å corresponds to an increase in the correlation between RMSD and score. Additionally, 'complete' scoring functions have a superior correlation to RMSD than 'reduced' scoring functions and 'mean' scoring functions outperform their 'cumulative' counterparts. There is little difference between 'radial' and 'normalized frequency' scoring functions.