The increased solubility of ppy2 and tmd in TCB enabled encapsulation of more molecules into Pluronic F-127 micelles, resulting in micelles with improved UC light output and reduced phosphorescence compared to unencapsulated UC pairs in organic solvents. To demonstrate the generalizability of the encapsulation method for UV-emitting TTA-UC systems, nineteen different UV UC pairs were successfully integrated into Pluronic F-127 micelles, allowing customizability in excitation wavelengths and UV emission ranges to satisfy the requirements of versatile applications. As a proof of concept, we used ppy2/PPO micelles to trigger photolysis of caged fluorescein with upconverted UV light at a focal point deep within an aqueous solution. UVemitting micelles provide the unique advantage of enhanced penetration depth and spatially confined light generation with low incident powers, which are inaccessible with direct excitation due to absorption and scattering effects. Precise, localized UV light generation at depth with TTA-UC has the potential to revolutionize a myriad of burgeoning fields, such as volumetric 3D printing, spatially controlled drug delivery, and precise optogenetic activation.