Additionally, the use of diaryliodonium salts led to the synthesis of aryl sulfones 28 and 29 in 79% and 68%, respectively. The Michael addition reaction of ethane sulfinate intermediate with N-phenyl succinimide resulted in the formation of imide 30 in 56% yield. A cine-sulfonylation reaction was applied for the synthesis of highly electrophilic alkenyl sulfone 31 with a yield of 70%. A two-step procedure was utilized for the synthesis of sulfonamides and sulfonate esters, involving a sulfonyl chloride intermediate, leading to medicinally relevant compounds 32-36, including derivatizations of Amoxepine and (+)-Leelamine. Primary, secondary, and aromatic amines, along with two alcohols were sulfonylated, providing the desired products in synthetically useful yields ranging from 27% to 68%. Lastly, we tested the unique capability of continuous-flow technology to combine different reaction steps in a telescoped reaction sequence (Figure ). The photocatalytic sulfinylation of propane was initiated in the first step under high-intensity light irradiation, with a residence time of 1 hour. Subsequently, the process stream exiting from the photoreactor was merged with a stream containing benzyl bromide, and introduced into a second flow reactor for nucleophilic substitution. A back-pressure regulator (BPR) was positioned at the outlet of the second reactor to maintain stable flow conditions across the entire reactor network. We opted for the soluble organic base, 2,6-lutidine, instead of NaHCO3 to prevent clogging. Consequently, the corresponding sulfone product 1 was isolated in good yield after both steps (86%, 80:20 r.r), demonstrating similar efficiency to our fed-batch approach. In conclusion, we have established a practical protocol for the photocatalytic conversion of C(sp 3 )-H bonds originating from lightweight alkanes into alkyl sulfinates, employing SO2. This methodology grants unprecedented access to a wide range of valuable organosulfur compounds bearing small aliphatic fragments. Although affordable and atom-economical, gaseous reagents are frequently disregarded due to a combination of chemical and practical considerations. In contrast, our study showcases their facile applicability as versatile reagents within the realm of organic synthesis, facilitated by the use of flow technology.