Similar differences are seen when evaluating the profiles of 100 mol% PBd22PEO14 membranes. Again, the SAXS data indicates much larger peak-to-peak distances compared to the cryo-ET profiles (108 Å and 66 Å, respectively), as seen in Figure and Figure . As shown by Figure and Figure , the peak-to-peak distance in the profile from the FFT correspond to the peaks found from the SAXS scattering curves (108 Å from both techniques). A closer inspection of the SAXS and FFT also reveals a small electron dense peak in the centre of the trough region, within the hydrophobic core. Again, this suggests that the information collected by SAXS is present in the cryo-ET images, but it is too noisy to be clearly resolved by our real space analysis of these images.