Each simulation reported consists of 20 polymers placed in a simulation box with initial dimensions of 147 Å × 147 Å × 147 Å containing approximately 105 000 water molecules, resulting in 3 wt.% solutions of each polymer. We used the OPLS forcefield parameters as prescribed by the PolyParGen webserver to describe the interactions of the polymers and the TIP3P water model. The same simulation protocol was followed for each of three simulations, which begins with energy minimization by steepest descent, followed by a 125 ps simulation in the NVT ensemble using the Nosè-Hoover thermostat to control the temperature (target temperature 300 K) with a timestep of 1 fs. Subsequently we ran 1 µs production simulations in the NPT ensemble using the Nosè-Hoover thermostat and the Parrinello-Rahman barostat to control the temperature (target temperature 300 K) and pressure of 1 atm, respectively with a 2 fs timestep while all hydrogen-containing bonds were constrained using the LINCS algorithm. In all simulations, the non-bonded interactions were cut off at 12 Å while the particle-mesh Ewald (PME) algorithm was used to calculate long-range electrostatic interactions. Appropriate burn-in times were calculated, with only the stationary portion of the production simulations used for analysis. A description of all of the analyses conducted on these simulations is described in the SI.