After 120 h, a conversion higher than 80% of the epoxide substrate 1a was observed. (R)-2a was obtained in 76% yield and 94.4:5.6 er in compartment 1 (C1) and (S)-2a was obtained in 78% yield and 5.6:94.4 er in compartment 2 (C2). This result demonstrates the feasibility of the initial hypothesis and opens new opportunities in the field of enantiomers preparation. The residual epoxide 1a was recovered at the end of the process in 9% yield exhibiting a 67:33 er in C1 and in 11% yield with a 33:67 er in C2. With these conditions in hands, several other racemic terminal epoxides were subjected to this process leading to both enantiomers of the 1,2-diols in each compartment [Fig. ] with relatively high conversions and good to excellent enantioselectivities. As expected, the results in terms of conversions, yields and enantioselectivities are similar on both sides of the compartmentalized reactor.