Numerous other types of reaction-type documents and data sets can be expressed in R-SPL but were not included for this paper due to resource limitations. We mention here the possibility to encode reaction transforms such as SMIRKS, or the LHASA type transforms used in SAVI , as well as electronic lab notebook (ELN) records stored in repositories such as Chemotion . Also, expressing tautomeric interconversion reactions is no problem in R-SPL due to the use of molfiles in which full connectivity can be listed (including hydrogens if desired). This is in contrast to RInChI , which suffers from the problem that InChI may be the same for at least some tautomeric pairs, in which case the reaction A ↔ A' becomes A ↔ A, i.e. no reaction is left.