We considered steric occlusion of the dimer interface by the glycans as a possible metric for dimerization. Several glycan moieties are attached close to the explicit dimerization region GlyB23-TyrB26 (Figure ), and there are several glycans large enough to sterically interfere with the dimerization interface (Figure ). We hypothesized that glycans that occupy space close to these residues, with high frequency in simulation time, will preclude dimerization.