We are particularly interested in MOFs that are ethane-selective since they are more useful from a process perspective. We observe a marked increase in the predicted ethane selectivity of the CoRE dataset compared to the experimental values in the K-C2 dataset, indicating that there are many structures with potentially higher ethane selectivity than have been explored thus far (Figure ). The highest ideal ethane selectivity that has been experimentally observed in MOFs thus far is around four. With these ML models, we identified five CoRE structures with an exceptional predicted ideal selectivity over six, even after taking into account uncertainty.