Although, Lignin-M MMT had good E.E/PLE results, but SPR is only 3.5% in 2days and therefore not suitable for aqueous release studies. In M MMT-PEIs, as we increase the organic content (PEI), the SPR results improve ( 40% M MMT-PEI: 81% in 10days while 2% M MMT-PEI: 65% in 11 days). S-M MMT showed significantly better performance(80.4wt%) in comparison to all other polysaccharides Among the M MMTs and hybrid MNP NCs, MNPs