The improved efficiency of QR-BH has also been illustrated in searching the higher dimensional energy landscapes of two co-crystal systems, which were used to investigate the influence of temperature and the allocation between quasirandom seeds and basin hopping steps on the performance of the method. The optimal temperature used in basin hopping was found to vary between systems, even for different space groups of the same chemical composition. The most reliable performance was found with high temperature (3000 K) and a large number of QR seeds with short BH trajectories.