Tablet Characterization. Tablets exposed to AMF were gently powderized by a mortar and pestle for subsequent solid-state analysis. The water content of the pure compounds, the physical mixtures and the tablets after AMF exposure was determined with a thermogravimetric analyzer (TGA; Discovery, TA Instruments Ind., USA). The experiments were conducted under a nitrogen gas purge of 25 mL min -1 and a heating rate of 10 °C min -1 from ambient temperature to 170 °C.