Procedure for the Synthesis of Disulfide Starting Material for Compound 11 5-bromo-2-fluoropyridine (1.76 g, 10 mmol, 1.0 equiv.) was added to a heat-gun dried 3-neck 250 mL round bottom flask equipped with a stir bar under Ar atmosphere, followed by 25 mL THF. The mixture was cooled to -45 °C in a dry-ice acetonitrile bath; i-PrMgCl-LiCl (10 mL, 11 mmol, 1.1 equiv.) was added dropwise. The mixture was allowed to warm to room temperature and stirred for 2 h (ca. 23 °C). Elemental sulfur (352 mg, 11 mmol, 1.1 equiv.) was dissolved in anhydrous toluene (35 mL); this mixture was added to the reaction mixture dropwise at -45 °C via cannula. The reaction was allowed to warm to room temperature and stirred for an additional hour. The reaction was then poured into a 250 mL round bottom flask containing a stir bar, KOH (1.16 g, 20 mmol, 2.0 equiv.), and K3[Fe(CN)6] (3.59 g, 30 mmol, 3.0 equiv.) in H2O (50 mL). The mixture was allowed to stir at room temperature overnight. Upon completion an off-white precipitate had formed. The reaction was filtered through a pad of Celite; the filtrate was then extracted with CH2Cl2 (3 × 15 mL). The combined organic layers were dried over MgSO4 and concentrated in vacuo. The crude residue was purified via column chromatography (9:1, hexanes:EtOAc).