Although several promising state-of-the-art approaches have been introduced, there remains a need for the development of a simple, complementary, and comprehensive methodology for the siteselective and substrate-oriented synthesis of unsymmetrical diarylmethane and diarylketone frameworks. Importantly, there is growing demand for methodologies that enable the synthesis of rare, yet valuable, benzylic deuterium-isotope-labeled diarylmethanes.