The lateral diffusion coefficients of the phospholipid species were calculated from the mean square displacement of their CoM. The trajectories of individual lipids were unwrapped using the NPT-corrected scheme of von Bülow et al. and analyzed with a Generalized Least Squares estimator to obtain the diffusion coefficients. The lateral motion of the lipids was measured with respect to the CoM of the entire bilayer, thereby eliminating the drift of the overall CoM.