For the sublimation of (S)-TLA scalemates with 60% ee and 90% ee (Figure ) the evolution of the enantiomeric excess of the sublimate over the course of the experiment clearly showed the occurrence of an enantiomer self-disproportionation in favor of an enantioenrichment of the residue. On the other hand, for (S)-TLA samples in the range of 30% ee to 10% ee of, a change in the order of the disproportionation resulted in a depletion of the residue enantiomeric excess (Figures ). In general, an initial collection of a preferential composition of TLA enantiomers of ca. 35-40% ee appeared to happen for all the samples subjected to the accelerated sublimation conditions independently from their initial optical composition.