Ammonium acetate (0.077 g, 1 mmol) was added to a combination of cyanoacetamide derivative 1 (0.905 g, 5 mmol) and N-bromosuccinimide (NBS) (0.890 g, 5 mmol) in 15 ml of dry diethyl ether. After 30 minutes of agitation at 25°C, the resulting combination was filtered and the filtrate was evaporated. After that, the final solid substance was washed with water, dried, and then re-crystallized with the proper liquid solvent to produce 2-bromo-2-cyano-N-(5methylthiazol-2-yl)acetamide