We did observe different behavior in terms of MPO score for the ROCS and ADV oracle, with the ROCS oracle behaving cooperatively with other MPO components. Improving the ROCS score via RL-AL led to commensurate improvements in the MPO score. ADV demonstrated competitive behavior with the other MPO componentsanecdotally a common occurrence when using docking-based scoring. In this case, the RL-AL system's acceleration of learning high-scoring components according to the oracle did not lead to any improvements in average MPO score relative to the baseline (although many more "hits" were found).