Both the kidney and tumour-bearing liver tissue sections were stained with hematoxylin and eosin (H&E) for post-MSI histological analysis via light microscopy. The H&E protocol was as follows: the glass slides were immersed in 95% ethanol, 70% ethanol and H2O for 2 minutes each and then immersed in haematoxylin for 3 minutes. Slides were then washed with running tap water for 3 minutes and immersed in eosin for 30 seconds following immersion in 100% ethanol for 1 minute and xylene for 30 seconds.