AASEQ tokens of EC 3.2.1.118 The biological reaction space appears to have a complicated structure. To understand the comprehension of the biological reaction space with the addition of the predicted reactions, biological reactions were visualised by a t-distributed stochastic neighbour embedding (t-SNE) diagram, which is a non-linear dimensionality reduction technique to convert similarities between data to joint probabilities and minimise the KL divergence between the probability distribution. t-SNE locates reactions into lower dimensional map. Here we chose to visualise reactions in two dimensions.