We have prepared a series of new compounds containing dithiolane or benzyloxy oximate to aromatic rings bonded to substituted anthranilic acid core. The synthetic procedure is straightforward, and the products are obtained in good to excellent yields after chromatographic purification. Excellent solubility properties and the presence of electron donor groups in the modified anthranilic acid derivative described herein may be advantageous in applications such as anthranilic acid derivatives-metal conjugate synthesis, for example. The efficiency of chromogenic sensing is more remarkably affected by the chemical environment of the anthranilic acid derivatives, depending on the presence of a protecting amino group or amide group. Taking into account these considerations, it is possible to optimize the uv-vis sensing of the molecules by structure modification. All these compounds possess multiple sulfur atoms and are thus capable of binding in a multidentate fashion to soft transition metal ions. A reaction of these ligands with late transition metal ions is a current focus in our laboratory.