RNA Loading Efficiency: Samples were run using gel electrophoresis, as described above. The resulting image provided by the ChemiDock imaging system was analyzed using ImageJ software. The RNA band intensity, which was correlated with the amount of RNA, was quantified with ImageJ. A standard curve was used to determine the amount of RNA loaded. Loading efficiency was also determined using Promega Quantifluor assay. Samples were exfoliated with 100 mM EDTA (pH = 4.5) and treated with 100 µg of heparin. Samples were heated at 60˚C for 10 mins. Quantifluor assay solution was prepared per the provided protocol. Samples (20µL) were added to the assay solution and evaluated with a plate reader (SpectraMax i3) with 492 nm excitation and 540 nm emission.