To exploit the potential of an NMR-based screening method for a systematic investigation of the coordination potential of different ligands to different metals, processes for homo-and heteroleptic complexes were defined. For a homoleptic screening with 12 different metal salts 6-17 (Table ), stock solutions of the ligands 5a-5c and an appropriate amount of metal salt were added to an NMR tube. Deuterated methanol was selected as a solvent due to its suitability for comparable experiments with benzotriazole as a ligand. The tubes were then shaken for 30 minutes to ensure thorough mixing of the metal precursor and the ligand for the reaction. Subsequently, NMR spectra of these samples were recorded. Successful complexation led to either a shift of the signal or a decrease of the ligand signals and their disappearance, indicating full conversion to one or more insoluble complexes. AgNO3, AgSO3CF3, AgCO2CF3, and RuCl3 promptly complexed with all three ligands, causing a shift for the aromatic signals and, most conspicuously, for the triazole hydrogen atom (8.7 ppm for ligand 5a, see Figure ). For AuBr3, the ligand signals disappeared almost completely due to the precipitation of the obtained complex. The NMR spectra of the successful experiments with ligand 5a are depicted in Figure ; the spectra for ligands 5b and 5c as well as for the remaining metals are given in the Supporting Information (Figures ). When no complexation could be observed in the first measurement at ambient temperature, the samples were subjected to a follow-up experiment. The samples were transferred to a suitable reaction vial, heated to 65 °C for 4 h, and the 1 H NMR measurements were repeated. After heating, a complexation with precipitation was observed for the samples with PdCl2 (see Figure ), but no Metal change in 1 H NMR was observed for the remaining metal centers. In the latter cases, the complexation was assumed to be unsuccessful. The shifts in the NMR spectra between different ligands and complexes with the same metal precursors are similar in all cases, leading to the assumption that the same coordination mode is present in all investigated complexes with the same metal precursor. Table : Summary of the screening results of ligands 5a-5c with the 12 different metal precursors 6-17. The complexation behavior was evaluated by comparing the 1 H NMR spectra of free ligands with the reaction mixture, including the metal precursor. ✓ = formation of a complex, ✓* = formation of a complex after heating, x = no complexation observed, x* = decomposition of ligand after heating.