among which 𝑘 1 ≪ 𝑘 2 , 𝑘 3 . When the molecular system is originally in the Kramers low friction regime (before the Kramers turnover , or the so-called energy diffusionlimited regime), the cavity enhancement of the rate constant 𝑘 1 will occur . This has been extensively discussed in recent theoretical work . When explicitly assuming that