A similar trend in anti-biofilm activity was observed for both 15c and 16c against fungi, with a significant decrease in the biofilm mass of both A. fumigatus (Figure ) and C. albicans (Figure ). In comparison to untreated cells, A. fumigatus treated with 15c and 16c at MIC resulted in 35-38% reduction in biofilm mass. Notably, at 2× the MIC, 15c and 16c induced approximately two-fold greater reduction in biofilm mass (69-73%) of A. fumigatus.