where kspon and kauto are the rate constant for spontaneous or autocatalytic incorporation, [EBads] and [EBmem] the concentrations of complexes on the membrane surface or inside the membrane (here SEIRA intensities are used directly as a proxy for the concentrations), respectively, and θ the percentage of occupied space in the membrane. Despite the ability of monitoring and even quantifying orientational changes using SEIRA, due to the surface selection rule, in this kinetic model we do not consider any reorientational processes explicitly. We assume implicitly that in each of the states of the model (Figure ) a specific but constant orientation distribution of EB species is adopted and remains unchanged.