Prior work has shown that species generated by radiolysis can diffuse hundreds of nanometers away from the LP-TEM image area and cause delocalized reactions. We performed a control experiment with two AuNRs positioned ~500 nm apart, with the particle on bottom right imaged at an electron flux of 68.3 e -/(A 2 s) for ~8 minutes (Supporting Movie 3) and the other AuNR never exposed to the direct beam (Figure ). Figures and show that the morphology of the AuNR exposed to the direct electron beam was altered while there were no changes to the AuNR outside the irradiated region. This indicates that mobile radiolysis products did not cause silver deposition or shape changes to nearby AuNRs. This outcome is expected given that the major component of the solvent is toluene, which generates primarily hydrogen gas and unreactive aromatic dimers and does not form solvated electrons, ions, or oxidizing radicals upon electron radiolysis (Table ). Prior results demonstrated IPA to be effective in suppressing radicalinduced beam damage of polymers, with simulations showing major radiolysis products formed included weakly reducing methyl ( • CH3) and isopropyl (Me2C • OH) radicals, as well as H • and es -, albeit at lower steady-state concentrations compared to water. It is noteworthy that toluene and IPA will rapidly scavenge H • to form hydrogen gas, effectively eliminating this reducing species. IPA is also an effective scavenger of OH • , which may form due to radiolysis of adventitious water. The concentration of solvated electrons is expected to be nearly zero due to several factors. First, the solvated electron G-value for IPA is 1-1.3 molecules/100 eV absorbed, about half the value for water (2.6 molecules/100 eV), and the concentration of IPA is lower here (2.6 M) compared to pure water (55.5 M). Solvated electron concentration could be further decreased by IPA scavenging of pre-solvated electrons and scavenging by hot holes. Finally, the Onsager length of toluene, which is the length scale over which ions experience electrostatic forces, is large (~24 nm) compared to water (~0.7 nm), indicating ions will rapidly recombine in toluene. Indeed, prior radiolysis chemistry studies have assumed the concentration of ionic species, including solvated electrons, is effectively zero in toluene. While concentrations of reactive radicals are expected to be very small or nearly zero, radiolysis of IPA generates several molecular products. A selection of IPA radiolysis products arranged by order of G-value is shown in Table . Focusing on redox-active molecular species, we incubated AuNRs in the silver nitrate precursor with various radiolysis products and characterized the AuNRs after incubation in dark conditions overnight (Figure ).