In lieu of capital-and energy-intensive cryogenic distillation, metal-organic frameworks (MOFs) could be used to efficiently separate and capture noble gases . MOFs are nanoporous materials with large internal surface areas to which gas selectively adsorbs [ ]. The selectively adsorbed Xe and/or Kr in the MOF can be desorbed and recovered, regenerating the MOF for another adsorption cycle, by reducing the pressure and/or raising the temperature. An adsorption-based process for noble gas separations at room temperature, in place of cryogenic distillation, could reduce costs [ ] and, in the case of SNF reprocessing off-gases, alleviate explosion hazards from the radiolytic formation of ozone that concentrates in the distillation column [ ].