Nobel-winning microscopy method suggests how DNA splits
Scientists using cryo-electron microscopy, the atomic-level 3D imaging method whose developers won the 2017 Nobel Prize in Chemistry, have suggested how the double helix DNA separates during replication. It was found that DNA follows a zig-zag path inside a channel created by two 6-sided rings where it interacts with two rings prior to being separated into 'leading' and 'lagging' strands.