depression
"So I'm a long term user, 13 years. Most of the reviews I'm guessing are short term. Well this is what you need to know before you start taking this, how it impacts you several years later.

In a word, negatively. My dose started off high (120) now 15. But I am now experiencing the side affects of what I call Mirtazapine abuse.  I believe it has progressively slowed down the reproduction of Serotonin and Noradrenaline and caused numbness through my nervous system. I now feel little sensation in my body, struggle to maintain erection during sex as result but above all I find it hard to feel emotion and thus have passion for anything. I can't compose music well anymore without forcing myself. Take this drug only on a short term basis. Be safe."