depression
"I started taking effexol 4 years ago to take the edge off my anxiety because my job is stressful and I have to shoulder a lot of responsibility.  I am on a daily 75mg dose. Overall, I have found it to be a great leveller, but the consequences of missing one dose is bad... missing 2 or 3 is pretty horrific, with head shocks, disorientation and feeling miserable. Really miserable. It's good medication, but do not forget it if you are travelling."