pain
"I have been on Opana about three weeks now for severe, chronic pain. I used to be on 60mg of Oxy-Contin and I took the first dose prior to getting ready to leave for work, after that I would spend the next 10-20 minutes vomiting. Opana doesn't do that to me in a 20mg dose and I find the pain relief much more lasting and comfortable.  The only medicine I ever took better than Opana for chronic pain relief was the once a day ,now defunct Pallodan."