lic acid deficiency
"I have some genetic defects pertaining to folate and I read people have had some success with methyfolate so I thought it might help with some of my issues (Depression/anxiety/ADD-PI ). I tried it as a individual vitamin and it made my brain fog worse, and I developed a feeling of being somewhere between tired/fatigued and agitated. I tried lowering the dose but it didn't help. However, for some reason, I have no issues with it intertwined with other vitamins/minerals in a whole food multivitamin....it seems very strange to me, but whatever works."