pain
"I have Synovitis/tenosynovitis , which is a severe, rare bacterial infection in my hand.  I had three operations, almost lost my hand, and it was gutted like a perch. Because of the types of antibiotics I had and still have to take  no opioids  worked at all. Oxy, Norco, Percacet nothing. Finally my pain doc came upon Nucynta. I started out taking four 100mg fast acting and 400mg of the ER. I'm now, after almost a year, down to 200mg ER and 225 mg of fast acting. I can't say the ER does anything at all but the regular was a home run. It's a weird high, can be hard to walk and talk, but stay in one place and be quiet. it really helps with the pain."