epilepsy
"Keppra was fine for me at first (500 mg twice a day) for 2 months. I suffer from complex partial seizures and experienced a grand mal recently. Then I experienced extreme tiredness, confusion, headaches, greatly increased my depression, could barely go from my bedroom to the living room (never mind managing leaving my house). I had to go back to my neurologist to get switched off such a horrible drug for me. Aptiom (once a day!) so far is a better choice for me."