abnormal uterine bleeding
"I've been on Depo for 6 months now, it's almost time to get my third shot. After my very first shot I had no bleeding at all for two months, just random cramps that were kind of annoying. Then at the third month I spotted very lightly for a week, then bled normal for about a week, then bled really really heavy for a few days. Then it stopped and I got my second shot. Two and a half months with no bleeding after the second one, then spotted lightly for over a week and no heavy bleeding. It seems to get better so I can't wait for the bleeding to stop completely. Also the only other side effect I have noticed is increased nervousness/anxiety. I have had a few anxiety attacks at night and I thought I was having a heart attack but it was nothing."