high blood pressure
"I was on this for about 2 years, 10 mg/day. It was clearly causing my legs to swell, but nevertheless, I persisted. Eventually, the elephant legs were too much for me to take, so I stopped the amlodipine, cold turkey. I lost 8 pounds of water over the next few days and low and behold, blood pressure went way, way down! I hit as los as 109/59, which prompted me to stop another BP med, losartan, which turned out to have been causing my chronic leg pain! I am now only on chlorthalidone, with a bp a bit high at 135/82, not sure which way to go next. Maybe try cutting salt. If you get the elephant legs from amlodipine,  maybd cut the dose or cut out the drug, try a different way to lower BP."