eczema
"I'm rating this a 'one' reluctantly because it truly worked miracles. I've wrestled with eczema for years and it has become quite painful.  An ER doctor prescribed this when I was there for an unrelated issue.  Within days my open skin and rough patches were completely gone.

But the side effects...I put on 15 pounds in under two weeks, with a painfully swollen gut, stomach pains and insomnia.  Upon visiting my regular physician, he refused to renew the prescription, explaining that these side effects, and potentially much worse, were due to the Prednisone."