depression
"I used the Kira brand of St. John's Wort because it was one of the ones used in the clinical trials done in Europe. While I feel this is a good brand of St. John's Wort, I had side effects from it which prevented me from continuing on it. I had diarrhea, gas and abdominal pain. I was unable to continue on the medication. While I was on it, I did not see any improvement, but I was not on it long enough. Also, I should note that I was only on 300 mg and got this side effect. Perhaps I am very sensitive."