polycystic ovary syndrome
"I have had diagnosed Polycystic Ovarian Syndrome since 1991.  Years of problems.  I tried Metformin the first time around 1995 and it did nothing.  I had weight loss surgery in 2010 and got to just below 200 lbs.  Hormones actually got worse with weight loss and a year later to the day, I had a full hysterectomy.  6 months later my only ovary started kicking into overdrive.  Crazy hormones, cravings and of course ruptured cysts...all the time.  

Doc decided to try metformin and said it could be different this time.  After a week I noticed great results.  2 weeks in I got so nauseated that I thought I had the flu.  Then the headaches.  They tried to diagnose me with migraines at the age of 42.  It was the Metformin."