obesity
"I was taking 400mg daily for chronic migraines, depression, and weight loss. It's very important to build up slowly otherwise the side effects can be extreme. I lost around maybe 50lbs while on it. When I got up to 300 - 400mg I started to have memory problems and sleep issues. After a while I felt like it had stopped working and dropped it, but that could have been from me forgetting to take it (memory issues remember). It takes a few weeks to a few months for the side   effects to fully wear off. I started at 235 or 245, and went down to 185. I'm now back up to 200. I haven't exercised in years, and I didn't change my diet (I probably don't eat as healthy as I should)."