depression
"My husband had a long (undiagnosed) history of depression.  The final straw was when his brother died in December 07.  Declining for the next 5 months, withdrawing more and more, not wanting to work, go anywhere, short tempered, paranoid, until finally he attempted suicide (not the first time).  Doctor prescribed Wellbutrin 75mg 2 x daily for 3 months.  He's been a different person on the medicines. He says "it makes him feel like he SHOULD feel, like he felt as a happy child, instead of what he's become over the years."  It helps with mood swings, helps him not overreact to small irritations anymore.  He increased to 3 x daily after a slight slump.  Don't try to stop without doctor's advice. He tried that and went back to his depression again."