psoriatic arthritis
"I was prescribed Otelza for psoriatic arthritis in my knees and psoriasis on my knees and shins.  After 6 months of regular usage, my knee pain has resolved but my psoriasis remains entirely unaffected, (I had way better visible skin results using Triamcinolone cream once a day at bedtime).  But what I wanted to share is why I came off Otezla this month:  I lost 23 pounds these last 3 months, developed a bowel problem where I had to rush to #2 after most meals, lost some appetite in general, and worst of all, I developed terrible anxiety and fears that I never experienced before.  I also lost my sense of joy overall, even though I did not quite reach the lows of depression. I am on day #2 of no Otezla. I am starting to feel better already."