depression
"Immediate lifting of depression; gave me my life back. Best to take 1/2 of 250mg very early on empty stomach with lots of water. I find it best taken around 5 am, go back to bed and wake later feeling great. Take another half before noon if needed, but, again, have an empty stomach and big glass of water. After a week or so, effects not as strong and can make you feel paradoxically very tired. Take 2-3 days off, and it will resume working. Be cautious and mindful of how your personality may be affected; reduce dosage if you're getting "too happy" overly friendly and too talkative. Also, it really focuses you and its good to make an effort to "break" the hyperconcentration by taking a break, a walk outside, hot shower. I've been taking 4 yrs"