schizophrenia
"In a few months I exactly doubled my weight -- constant ravenous appetite.  Started on 40mg a day.  But after 15  years of taking it & fighting confusion & appetite & somnolence, even when I got it to 2.5mg and lower, I still had the same objectionable side effects.  Would have been better to take it short term (maybe 3 months) instead of years.  VERY VERY hard to taper off of it no matter how slowly you do it.  I don't think I would ever take it again unless it was a life-or-death situation."