depression
"This is a great add-on medication for depression. I am compound heterozygous for the C677T and A1298C MTHFR mutations. I was taking Celexa and Wellbutrin and still having frequent depressive episodes when I first started taking the Deplin. After about a month on Deplin, I weaned off the Wellbutrin. We later lowered my dosage of Celexa too. I did try to wean off Celexa completely and use Deplin as mono-therapy, but ran into issues.



I've been taking Celexa 20mg and Deplin 15mg for over a year now and it's still working great!"