depression
"I'd been on Wellbutrin/Wellbutrin SR for over 15 years and it worked great until about a year ago when I started feeling I'd built up a tolerance to it.  Seeing that Aplenzin was basically the same, but in hydrobromide form instead of hydrochloride, I figured it would "trick" my body into reacting to it as a new medicine without losing the benefits. With the blessing of my psych doc, I switched and it appears to have worked.  I'd give 10 stars, except for the high cost."