abnormal uterine bleeding
"I've been on depo since I was 13, I'm now 34. It has worked wonderfully for me and I don't really have any serious complaints. But a couple years ago, I started spotting out of the blue! I've never had that issue before, as my periods had completely stopped. Not sure if it is normal or not, but it's extremely painful and there is no way to track it or plan for it."