urticaria
"I am beyond disappointed that Xolair had no effect on my chronic uticaria.  For 18 years I have suffered with the disabling disease.  My hives are so bad, I can not even wear clothes, because anything touching my skin causes unbearable pain,  swelling, redness and my eyes become bloodshot/swollen and puss comes out of them.  I  also have full blown Lupus and I am  Human leukocyte antigen (HLA) B27 positive (Hl1-B7 positive).  My life is completely ruined and over.  Can't work,  have zero support from anyone, live in poverty (than you SSD), lost my home.... horrible situation.  Xolair did nothing. Not one thing!  Pain, redness, swelling, itching still there after 2 months with two treatments of two shots a month.  Beyond depressed.    It is hard to live like this."