osteoarthritis
"I had injections Jan 2015 in knee where I previously tore the cartilige and had it debrided.  Degeneration is bad but I'm too young for knee replacement and really don't want it.

I had several steriod shots prior and they worked but very limited time.  It did take some time for the Euflexxa to "kick in".  I think it was about a month before I kind of stopped noticing my knee.  It's now Oct 2016 and I'm just now noticing my knee again because I have degenerative problems in all my joints and now it's the spine.  The physical therapy is putting a strain on my knees (leg press, quad stretches) so now it's owie again.  Until now I've been able to cycle daily about 10 miles without too much problem unless we are talking steep hill."