depression
"After 3  years of a dark depression, I hit bottom and started Wellbutrin 300mg every day. Over the next 2 years, I've lost weight (because I was trying), I quit smoking (because I wanted to) and I discovered a small part of life that was tolerable (a small part). I increased to 400mg in July because I felt myself slipping back to the dark place and it's the first time I've noticed side effects: marked insomnia, unfavorable irritability, a little bit of numbness, I crave sweets and I don't seem to want sex as much. So I'm thinking 300mg was the therapeutic dose for me and will call my doctor to see what the plan is. On the bright side of the 400mg, I'm sitting here tonight writing a positive review for the medicine I believe in."