rheumatoid arthritis
"Been taking mtx, folic and Plaquinel for 1.5 yrs. My biggest side effect is lack of appetite. Not sure if it is the MTX or plaquinel causing this but as a result I feel I have no energy or muscle mass left. I wonder whether it is better to take the drugs or let the RA runs it's course. History of cancer in the family but not seeing any reference to that side effect here"