ankylosing spondylitis
"My husband switched Rheumy's & the new doc felt Remicade was not longer controlling his AS as his C-spine has started to fuse.  After 3 months of talking up the benefits of Cosentyx my husband made the switch.  Worse decision ever. Quality of life is horrible, he lives in his recliner once again. Back pain severe. Joints swollen, which never happened before. And the worst part 3 bouts of upper respiratory infections, last one is now pneumonia.  Doc says at first not the Cosentyx...but it's a side effect I say. Duh.  Very disappointed.  Hope he can restart Remicade."