depression
"Started on 20mg daily and went up to 40mg. Little or no mood changes. Some of the worst side effects I've experienced: Loss of libido, erectile dysfunction and premature ejaculation. Pain with urination. Initial loss of appetite which then seemed to swing the other way and make me want to eat constantly. Very increased irritability, to the point that I caught myself screaming insults at the computer or other drivers (in private, thankfully), pounding my fist on the desk, and having to plug in headphones and crank the music loud enough so that all the little noises around me didn't make me scream in anger."