progesterone insufficiency
"I've been taking Prometrium for about 4 months now, & for the most part have no side effects. It works like its suppose to and keeps my progesterone to where it needs to be. However, just an FYI you should always take it before bed with food & I mean lights out in bed to sleep not watching TV or playing on your phone/tablet. If you take Prometrium & not go to bed it will cause a euphoric (high) feeling which may be unsettling to some people & may cause panic, because it does feel really weird."