gout
"First had gout at 38 - too much booze (about 50-60 units a week for years and years) plus a diet rich in oily fish. Didn't know what it was for a couple of years - diagnosed at age of 40, 18 months ago, and went on daily Allopurinol.  Haven't had a twinge since. Am trying to drink less, albeit not very successfully - nevertheless,  would recommend this drug 100%."