constipation
"It's going to cause cramps and discomfort because it stimulates the bowel to move. I put up with the discomfort because other laxatives aren't as effective for me. I'd suggest using Ducolax with a separate stool softener, right before bed. Maybe even take stool softener in the afternoon, then Ducolax at bedtime. I slept through cramps and had a movement in the morning. When I took it in the late afternoon, the cramps were pretty bad. Drink water/liquids lots."