constipation, chronic
"I am a healthy type one diabetic who in November of 2011 completed my first marathon.  That changed in May 2011 when I was diagnosed with gastroparesis. I've been hospitalized 32 times since then and suffer chronic constipation that, like every one else here, couldn't fix it. It is the most miserable feeling in the world. Clothes don't fit, painful itchy hemorrhoids that cause embarrassing bleeding through my clothes, and hours in the bathroom. I've been on the medicine for two weeks and it's an absolute miracle! I started at 290mcg and realized I could handle 145mcg. The lower dose allows me to have a regular schedule and no accidents. If I feel like I'm backing up at all I go to 290 for a day or two.  "