rheumatoid arthritis
"Following treatment for acute auto-immune disease of the brain I suddenly developed RA symptoms in my hands and feet - dropping things all day, severe overnight swelling and pain.  Two previous medications prescribed by my rheumatologist were ineffective.  Tried Methotrexate (8 x 2.5mg once/week   folic acid) two days ago and 50% of swelling and 90% of the pain are gone; can make a more-or-less painless fist with both hands, easy to type first thing in the morning (woo hoo) and happy to be alive."