tourette's syndrome
"Clonidine was the first medication I tried after being diagnosed with Tourette Syndrome at age 14. I took it for about a month, and it heavily sedated me, thereby helping my minor tics. I took it again for about a week when I was 21, 0.1mg prescribed by another neurologist. This second time, I did not notice any sedation, but instead experienced day of constipation, so I discontinued."