osteoarthritis
"The first time I had a synvisc shot it worked really well with no side effects. The second time I had a shot in both knees and was in a pain, had cramping in my calves and was pretty miserable for about 2 weeks.  Now I have popping in my knees as if the fluid got underneath the knee cap or around that area so every time I walk my knees pop and it drives me crazy.  I never had this before I got my last shots, so now not only do I have osteoarthritis due to loss of cartilage I now have another complication with every step.  I don't believe I will have another shot, and I wish there was some sort of compensation for this."