restless legs syndrome
"I have been taking Requip XL for a few years now.  It worked great at first, but now I get rebound restless legs syndrome almost every afternoon.  I also find that if I'm late taking it, or if I take it after the rebound RLS starts, that it takes hours before it helps.  I usually end up taking Percocet to stop the painful twitching.  It's better than taking nothing at all, but I would love to go 24 hours without the pain!"