schizophrenia
"My sister had been on clozapine for 11 years! She was doing great; showering on her own, changing her own clothes (for those that know people with schizophrenia then you these are major tasks in of themselves) she was even volunteering, working out and DRIVING!  Just last week her doctor, whom we have grown to love and depend on, told her about Vraylar.Of course SHE wanted to try it.Sure she still had the voices in her head but they were quieter and she could always tell the difference between her world and reality.  After 3 days on Vraylar she went full blown maniac! Throwing things,yelling at us in tongues ,hitting and kicking us. We finally got her to the ER and got the Clozapine back in her system and the Vraylar out.She's still in CCU."