hashimoto's disease
"43 years old female, 5'7", 76 kg. 
I used to be 56 kg , and in a matter of 2 years I reached 80 kg after quitting smoking. I also had a plethora of other problems, amount which lethargy, extreme fatigue , depression . 
My doc discovered by accident my TSH was 10 , plus huge antibodies values. 
Started me at 50 mag Syntroid and I went up from there. 
I am now at 175 mcg , huge dose, and feel fantastic.  My blood values are low,TSH , upper limit T4. I kind of talked my doc in increasing the dose.... as his choice was 125 mcg and I felt that was too low . 
I finally have the energy to go to the gym .  I feel like my old self. 
I LOVE  Syntroid and I hope he won't lower it for me ."