pain
"I had arthrodesis surgery to fix my crushed right thumb 08-03-2010, and have had severe pain in it ever since.  The doc prescribed hydrocodone and oxycodone, which worked very well.  So I would not become addicted to those, he switched me to tramadol, 50mg, 2 every 4 to 6 hours as needed.  First time I took them, before bed, I had a terrible night.  Normally, I'm a sound sleeper, but I tossed and turned and did not get a wink of sleep, which is not one of the published side effects.  So, that first time was my last.  Meanwhile, I'm in pain."