rheumatoid arthritis
"I have severe RA and was started on MTX about 6 months ago already maxed out and pain and inflammation was doing major damage.  Two years ago I was running a mile several times a week and when the RA hit  I could not even open my bedroom door.  Recently was started on Embrel.  After the first shot I noticed a 25% improvement with pain and stiffness.  I did not find the shot painful as some describe, but I had already been self injecting the MTX.  No other side affects thus far.  Looking forward to my second injection this week and continued improvement."