restless legs syndrome
"Mirapex (Pramipexole) is truly a wonder, it takes away 99% of my symptoms if taken early evening.  I've used it for 10 years or more now and it hasn't failed me until lately, as my dose is now at 1mg at night and 0.5mg in the morning.  My symptoms do come up early enough to get me out of bed in the morning once in a rare while."