melanoma, metastatic
"Had Isolated Limb Profusion (Left leg) at MD Anderson Cancer center in Houston in Nov 07. Three cancer tumors returned in the same lower left leg in May 2011. In Aug 2011, started Zelboraf at  4 x 240mg pills twice a day (1960mg total a day). Two tumors disappeared within a month of taking Zelboraf. One resisted for six weeks total and was gone. CT and MRI's could find anything after scanning. In July 2013, the one that resisted, returned along with a 5mm nodule. Had some of the complications I was warned about but nothing serious, just uncomfortable at times. Seems like now the cancer is not responding to the Zelboraf and now looking for alternatives. It gave me more years to live with my daughters. Zelboraf is GREAT."