depression
"I have taken Trintellix for about 6 months after trying absolutely everything else.  At first I was thrilled at how much better I felt.  I could concentrate again, was sleeping for the first time in over a decade, and felt more motivated.  However, For the past few months, I have been feeling moderately to severely depressed, so much fatigue that all I want to do is sleep, and itching and muscle pain.  Most disturbing though is how little I feel like myself.  Anger, mood swings and feeling irritable are affecting my relationships and my desire to help myself.  Time to discuss discontinuing this med with my doctor."