rheumatoid arthritis
"I've had RA for two years now. Started MTX about 7 months ago.  I started to get worse, not able to open bedroom door in the morning.  Stiffness lasting most of the morning and joint pain all day.  MTX increased to max dosage without improvement.  I take MTX injections.  Started Embrel a month ago, much improved with first injection.  Now morning I do not have a lot of stiffness, still have joint pain but it is improving as well.  My RA was rated as severe.  I've had no real side affects from either drug. I have muscle pain in my legs which I understand can be a side affect of Embrel but it beats the joint pain.  I had read that the Embrel injections were painful.  I personally did not find that to be true."