ibromyalgia
"Fourteen years on Ultram, initially prescribed for migraine relief.  As a painkiller, it has never worked for me.  However, there is a little rider attached to the medicine information when I pick it up from the pharmacy about how it may be used for purposes other than pain relief.  For me, it keeps my joints fluid (I now have arthritis as well as fibromyalgia), and most definitely acts as a mood elevator.  No high or buzz, but a feeling of stability.  Because I metabolize ALL medicines at a high rate, it takes more 50mg tablets than the FDA recommends to get relief.  Wears off fast,  but one dose in the morning seems to keep me stable.  Also I cannot sleep without it.  So many, many different reactions to the same medicine."