psoriatic arthritis
"I was put on Humira when I was 25 and I am now currently 31.  The first thing I noticed was that it cleared up my plaque psoriasis very quickly.  My nails and scalp looked normal within 3-4 weeks.  I have PsA in my spine, ankles, knees and hands.  I was having trouble walking and experienced chronic fatigue which caused me to gain 20 lbs very quickly.  I would fall asleep from exhaustion after getting myself showered and dressed.  After the Humira took effect I had my energy back.  I could exercise again and I was back to doing the things I enjoyed.  I still experience flare ups (mostly due to stress) and I still have difficulty sitting for long periods of time, but this drug was life changing.  Vicodin helps me with the flare ups."