psoriasis
"I am a physician; I took acitretin as prescribed for plaque psoriasis. After about 3-4 weeks I started to feel very unwell - weak, tired, unable to cope with minor slopes (I have trekked in the Himalayas, Yosemite, Highlands of Scotland, etc). I was not drinking alcohol at all - not for four months before or after. Acitretin was discontinued and the adverse effects reported (yellow card) to the UK regulatory body. The malaise and weakness persisted after stopping the medicine but gradually resolved over a 12 month period. "