restless legs syndrome
"For nearly ten years I struggled with restless leg syndrome, a truly miserable and frustrating condition.  The only 'treatment' I found to be effective was to get up and walk about.  However, between about midnight and 6:00 a.m. this becomes quite inconvenient.  Soaking in water as hot as I could stand worked only for a few seconds.  Relief from massages was also extremely temporary.  Initially I tried Requip, which seemed like it might be helping a teeny bit, but left much to be desired.  Later a neurologist switched me to Mirapex.  Following a 'breaking in' period, at long last I found relief from this miserable condition.  As long as I take my daily doses, I have relief.  So far, so good."