restless legs syndrome
"I've had severe rls for about 20 years.  I used Vicodin for about 6 years.  It worked really well except for needing to take more in the middle of the night (needed extended release).  Moved to Hawaii and doctors won't prescribe vicodin.  Tried Ropinorole which worked well until augmentation began.  I've been on the Neupro patch about a year and it's been wonderful except for skin irritation.  In the last month I've started having rls sometimes when I go to bed.  I thought maybe the patch had come loose or maybe even a bad batch of patches.  I'm on a new box now and still having the problem so I guess augmentation happens with Neupro also."