acne
"I have been taking Spiro for about 5 1/2 months and am only now seeing and experiencing results-- so be patient! I started out on a 25mg dosage twice a day, moved up to 50mg after 3 months and just recently increased to 100mg. Do not be discouraged by the initial outbreaks. I pair it with Differin, which is a topical cream that helps with scarring but my face has finally started becoming incredibly clear for the first time ever. The side effects that I've experienced got more dramatic as I increased the dosage but were never severe enough to quit: Irregular period (sometimes twice a month, sometimes not at all, but will regulate itself after a while), Shortness of breath when exercising, and I have lost about 6 pounds in the last 2 months."