depression
"I have BP2 and was put on Remeron for a crushing depression that lasted for several months, which Cymbalta was not helping, even though I had been on it for many years. At first, Remeron was my miracle drug. Within 48 hours, my depression had broken and I no longer needed to take Ambien to sleep at night. But within a month, I put on 14 pounds and that was completely unacceptable. I went off Remeron immediately, with no withdrawal symptoms. If you are depressed and don't have weight issues or are experiencing decreased appetite, this is the drug for you. But for anyone that struggles with their weight, I would not recommend it."