mania
"For some, lithium is the most effective choice for bipolar mania.  Unfortunately for me, it's not.  My body rebelled against it immediately and without pause for its entire 60-day 'trial'.  My bowels were never solid the entire time.  I'm amazed now that I never recognized any dehydration symptoms over that time.  It worked for my dear departed mother, but not for me, but I gave it a shot."