irritable bowel syndrome
"I'm not sure that this was a direct result of taking Linaclotide, but My experience was constipation. My doctor prescribed it because I had bowel movements almost every day, but the stool was so hard and large by the time it reached the end of me that I couldn't pass it. So my bowels would move...but the contents couldn't exit. I started Linaclotide 145mcg as directed on a Wednesday, by the next Wednesday I was very uncomfortable, bloated, clocked an extra six pounds (surely not actual weight gain), and hadn't passed any stool or had any arrive in my rectum. Pico-salax was needed, the meds stopped, and I'm still not returned to baseline (14 days from dose 1). We're not sure what's happened."