osteoarthritis
"I had Supartz injections several years ago with good results.  When I moved, the new Dr said Euflexxa had fewer side effects.  This was certainly not the case for me.  I was in constant pain and almost a cripple for 6 months. I couldn't walk up stairs, or do most of my normal activities.  I spent most days on the couch with bags of ice on both knees. Cortizone was useless. There appears to be no treatment for this side effect.  I am an active person, of normal weight.  Both knees are still swollen, but the pain is better than it was. I read that it could be another 6 months before I feel better.  I wouldn't recommend this medication to anyone.  It's not worth the risk of losing 6 months of your life that you'll never get back."