heart attack
"Make sure you review your dosage with the doctor.  As the others stated, it will make you tired and lethargic.  It also has had an effect on my ability to have a discussion without forgetting a word or two. My doctor gave me a dosage of 100mg/2x daily.  I wound up back in the hospital due to my heart rate being a low 32 beats per minute.  The hospital treated it as a failure with the original stent and went back in to check the previous operation.  That was over a year ago.  We tweaked the prescription down to 50 mg once a day, but I never got out of the lethargic state."