birth control
"I started this bc when I was about 17 years old. I had few side effects but over the course of a few months I started developing UTIs. I'd never gotten one previously but at the time I didn't associate it with the bc pills. The UTIs become frequent, multiple UTIs within a month even peeing after intercourse, taking cranberry supplements, wearing looser clothing, etc. After a couple years my prescription ran out (away at college). The UTIs immediately stopped and I haven't experienced one since. 

Another long term side effect I experienced was depression and irritability. I was treated for that and am still recovering from the depression. I've been off the pill for over a year now and things are finally just now normalizing."