acne
"This antibiotic worked wonders for my moderate acne very soon after starting it in November 2016 (in combination with a Tretinoin cream). It consistently prevented my cystic acne from emerging and reduced inflammation, I had virtually no breakouts on my entire face. However, it started to lose effectiveness in July 2017 and by August I was seeing discoloration in my thighs. It was like large bruising that wouldn't heal and it was massively noticeable. I saw that this was a common side effect after buildup of the medication in the system, so I stopped taking it. They've since fully healed. I'm continuing to use a topical cream (now Differin) but it's having virtually no effect on my acne, which is now as bad as before. Back to square one."