rheumatoid arthritis
"I started Simponi in April and have now had four injections.  It worked the first night, my shoulder pain was gone and I have slept without pain since.  I have had no reactions whatsoever.  The drug has lasted the full month every time.  In the month previous to my first injection I took 150 Tylenol 3's for the pain.  In the 3 months since  I have averaged 30 per month.  My shoulders, wrists, hands, and knees are almost pain free with very little stiffness.  I still can't work but at least I have my life back, thanks to Simponi.  Methotrexate was too hard on my kidneys but I still take 20mg Arava every other day and Plaquenil and Diclofenac daily.  I also take Ramipril for the raised blood pressure the drugs have caused."