constipation, chronic
"Same as others here, constipation for 20 years (currently in my 40s). I'd go weeks without a movement, became terribly ill.  Laxatives caused intense cramping, nausea and fainting, so when Miralax came out I was thrilled.  5 years later on the Miralax almost daily, my doctor suggested the Linzess.  Started samples (245mg) until I could fill my (145mg) script, and I don't recommend the higher dose - terrible cramping, nausea and unpredictable movements.  After starting the 145mg dose, I'm doing much better, with a very productive movement (or 2!!) every day, but I'm disappointed. I'm fairly torn to shreds with fissures from hard, forceful movements.  Hoping for improvement soon!"