pain
"I was on Percocet 10 / 325 mg for about 10 years, and I asked to switch first to a bupephrine patch, which I was too terribly allergic to and had awful withdrawal symptoms from, and then I asked to switch to hysingla because I felt like a pill Junkie and disliked the high/low cycle. Plus, I was starting to cheat and take two each morning of my 4 per day allotment.  With hysingla, I had to endure titration to get the right med strength so started out with 10 mg for two weeks. I barely felt relief. Then moved up to 20 mg for two weeks but didn't feel too much difference from 10mg. Then tried 30 mg for two weeks and I could tell it was working but not well enough, so now moving to 40 mg. Hopefully this will be the trick."