irritable bowel syndrome
"I have had Irritable Bowel Syndrome-C for most of my adult life, and this medicine is the only thing that calms everything down. I do not take it every day - only when things get intolerable, and even then I usually try to take it at night, as it does cause drowsiness and "cognitive impairment."  It definitely works, though! In my opinion, it's worth a try."