herpes simplex, suppression
"I had eczema on the skin accompanied by fever and joint pain for the first time last year and was diagnosed HSV2 by IgG positive test. I took Valtrex for two and a half month and the following IgG test was negative. I repeated the test three month later, still IgG negative. My doctor does not know why. I would suggest those that have been taking Valtrex for a longer time (at least some months) right from the first outbreak to take a new IgG test. Maybe the Valtrex period of some months assists in the body reducing the number of virus through repeated life cycles such that it does not cause IgG antibodies. I like to add that the HSV1, which I had since long, gave positive IgG response in all three IgG tests."