pain
"I've taken Loratab 10/500 for about 3 years for osteoarthritis in the knees and I don't know what I would do without them. I was taking them prior to my knees being replaced and still take them for hip pain. The only negative side effects I've noted is occasional constipation, which is consistent with any narcotic. I take 3-4 every day, but I have begun to notice that they are not as effective as before. I'm sure I'm developing a tolerance to them also. But I would recommend them for chronic pain for anyone who can tolerate them."