ulcerative colitis
"I haven't been able to tolerate any drug during the 5 years I have been officially flaring and diagnosed with UC. Despite this I know I had this nasty thing for the past 20 years. To put it plainly, Humira worked for 2 months, then failed. Now Entyvio worked for 1 month maybe and seems to be placebo now. I oscillate between very bad bloating and constipation and then diarrhea. Since on Entyvio I am unable to sleep laying down from the pain, and I have no ability to form a normal stool - it's either Diarrhea or it's pencil thin or pebble like. I do not feel like this medicine works and is just another step in the long journey toward surgery. I hear how biologics help people but I remain unconvinced."