constipation, chronic
"My experience of over 40 years of IC (started after a hemeroidectomy). I was on the protocol for Cisapride at the University of Pennsylvania in the 80's. It worked great, they took it off the market. However, 3 daily was recommended, I had to take 10 daily. Been on Zornorm, Amitizia Reglan (horrible), then, Linzess 290 & 145, it was the answer to prayer. However, I would take it and then suddenly it would stop working, I knew there had to be a reasonable answer. However, I would switch then to the samples my Dr gave me, and, the Linzess would work again. Finally, in front of the Pharmacist, I took the seal of both bottles of Linzess and there was barely a dusting of powder inside of them. The capsules were nearly empty, they were replaced."