pain
"After failed back fusion surgery L4 L5 S1 nothing would touch the pain until Opana ER. I was taking 20 mg three times daily and have cut back to 5 mg 3 times daily with significant pain increase because I thought I was losing my mind. I seem to have built up a tolerance and either need to increase again dramatically or find something else.  Have heard that you can easily build tolerance to Opana.  I am your proof. "