plaque psoriasis
"I was on Humira for several years, and it worked great. Eventually though, my body started making antibodies against the Humira, and it started working with less efficacy. I then switched to Otezla. I once did a trial study of a pill version of a ps med (the only one I had ever heard of at the time), and it worked great, so I was pretty hopeful as I started Otezla. 

For me, I could literally feel the Humira leaving my body. For those of you with bad ps, I started feeling those pins and needles again. I gave Otezla almost 6 months before calling my Rheum doc and asking if I could try something else and here I am. I'm not scaling a ton, but I'm constantly itchy (hard to sleep). I've tried a lot and some have worked. For me, Otezla doesn't."