migraine
"I have used this medicine for 60 years and have found that a dose of 0.5 mg  concurrently with 50 mg caffeine taken in conjunction with 3 x 200 mg pills of ibuprofen (total dose 600 mg) enables me to continue my life and work without   too many problems. The alternative of not taking this medicine is horrifying with nausea, vomit, head pain and total dereliction for 2 days. I have also experienced cramps and breathing difficulties without the use of ergotamine tartrate."