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"I Used to be on Trinessa, but my pharmacy switched me to Triprintec because they were no longer carrying Trinessa. At first, it was horrible. I had extreme depression and mood swings, migraines, nausea, fainted once, and it caused irregular heart beats. I've been on it for 3 years now and the only symptoms I have are migraines and nausea. The nausea can be extreme some times. The only good thing I can say about the medication is that I have not been pregnant and have had no problems with acne. "