acne
"I have horrible hormonal acne and Bactrim has been the only systemic drug that has helped. Problem is I took it for years, randomly when needed.  After years of usage, oddly I became allergic to it.  I broke out in large red spots that were extremely sensitive.  It's a serious allergy. I have permanent dark bruises all over my body and it has been years since I've used it.  If you haven't tried Bactrim.  Try it. It will work for you."