sjogren's syndrome
"I have been on this medication for approximately 8 years. Before I started this medicine I was in terrible shape. With Sjogren's syndrome as my primary autoimmune disease and rheumatoid arthritis as my secondary autoimmune disease I was in terrible persistent  pain, had terrible joint ache and was incapacitated for about four months before finally being diagnosed and given this. Along with steroids, this medicine, and some regular doses of ibuprofen I found I was able to be mobile again, to go back to work and have a quality life again. 
I have not found that being on the same the dosage has lessened it's effectiveness over the last 8. During major flares especially, it would be near impossible to have a good, healthy life."