abnormal uterine bleeding
"I have been inadvertently taking this for over a year now.  I stopped my period myself with Lutera, which is the same strength and medication in Lo Seasonique so I've switched to LoSeasonique to save money.  When I first started taking it, I spotted for a long long time and if I take it even one hour later than my scheduled 4pm time I inevitably get cramps for two days.  If I miss one more than one day in a row I will spot for a week or two and feel as crappy as I used to whenever I got a period.  My periods did NOT get less painful on the pill and that is why I stopped it all together and I couldn't be happier.  If you can wait out the spotting, it is so worth it."