bipolar disorde
"I am Bipolar Type I and was switched to Saphris from Seroquel by my psychiatrist.  One dose and I began having suicidal ideation that I hadn't experienced in years. I had the presence of mind to call my psych doc immediately (it was a weekend) but she didn't call back.  I am a nurse and should have known better, but I took it the next day.  After the second dose, I was frightened I would act on the impulse.  Luckily I have a very supportive and observant husband.  I called doc again and she said to stop immediately, of course, as I should have after the first dose.  I saw her on Monday and went back to Seroquel.  Less severe side effects included numbness of my entire tongue and sick-feeling somnolence."