bipolar disorde
"I had been on Seroquel since 1997 and had gained a lot of weight.  I also had the side effects of type 2 diabetes, high cholestoral, etc. from taking it so long.  But Seroquel worked for me.  So in an effort to loose weight and the "bad" side effects I switched to Latuda.  Lutuda didn't do squat for me in the sleep department, so I ended up taking a half pill of Seroquel and a dose of Latuda.  This worked well for about a year.  I lost a ton of weight and my overall health improved.  However, I slipped into a major depressive episode in less than a year and had to go back to the "tried and true" Seroquel.  Feeling better, but gained back a lot of weight.  Never thought a drug marketed for BP depression would make me depressed."