bipolar disorde
"At one point, I was on regular seroquel as needed and seroquel XR daily. During this time, I gained a lot of weight that I just could not take off. I was prescribed the seroquel as needed, 25 mgs up to 3 times a day. 
Later on, I was going through something else and seroquel had just gone generic. My psychiatrist put me back on the 25 mg pill as needed. I rarely used it and this time I didn't gain any weight from it, which I was relieved about. I know they say that the lower doses are supposed to make you really tired, but that didn't seem to have any effect on me."