ibromyalgia
"I took this for my  chronic central pain state and it was a very effective pain killer as long as Tapentodol not taken simultaneously, then skin itch develops at low dose of EXTENDED RELEASE (capsule) 100mg nocte and 50mg morning. The itch was severe by time dose increased to 200mg am and nocte but no,other side effects except possible responsible for my delayed circadian Rythm disorder. Waking constantly before 4am sleeping 4-11am so very inconvenient, but others side effect free and a good pain killer.  Remember to check if you have been prescribed the normal tablets or extended release capsules and that pharmacy has given you the correct kind."