irritable bowel syndrome
"Worked great for the first 3-4 months then nothing. Went right back to same misery I have dealt with for 20 years. Doctor even increased dosage  even though people without a gallbladder are not supposed to take the higher dosage. The higher dosage actually made things worse for me and the cramps last even longer than they normally do which is pretty bad so since it was no longer working I stop taking it. It did seem like a miracle drug at first but unfortunately I'm one of the people that it no longer works for after three or four months."