depression
"I'm a middle aged professional that's dealt with depression and anxiety since my teen years.  I've tried many different types of medications that target anxiety and depression, albeit with mixed results.  

My depression, stress, and anxiety levels had gotten worse within the last year (haven't been on any medications for over 10 years), so I went to see my doctor. I've been taking Effexor for about a month now and it's, by far, given me the most relief over any previous med.

Stress levels have gone way down as I no longer tend to ruminate on things out of my control. It's much easier to drop the negative thinking and move on to something else.  Anxiety and depression have also been greatly reduced.  
No major side effects for me (at 37.5)"