ibromyalgia
"I began Savella with the titration pack and worked up to 200 mg daily.  While it did help with the overall aches, the side effects were unbearable.  I gave it 5 months, hoping they would pass, but they got worse. I experienced horrible depression, and extreme agitation. It was so bad that my family intervened. It was impossible to live with. Irritable, agitated, crying a lot and so depressed.  I looked forward to bedtime so that I could sleep and not be able to feel these horrible emotions. I did not even want to leave my house, I kept the curtains closed and isolated myself as much as I could.  I have NEVER had a drug affect me like this. Back to Elavil for me now."