rheumatoid arthritis
"I have been taking 200 mg of Plaquenil 2x/day for about 8 weeks. I notice stomach discomfort even though I take it with a meal. The one side effect I don't see mentioned anywhere is that it lowers my iNR and I've had to increase my warfarin dosage.  I do see a great change in the amount of pain in my joints!!  I actually have days that I feel good again!!  Praise God!"