depression
"I've had depression for 12 years, and have been on Paxil about 10. The Paxil worked for a few years, but the anxiety and depression slowly worked its way back into my life. So along with the Paxil they added other drugs (Effexor, Wellbutrin) but they made me even more anxious. I was finally put on regular Seroquel and found it worked for a little while, but I was so tired all the time I couldn't function the next day. I was literally fired from 3 jobs from being stuck in bed and refusing to get up. I was switched to Seroquel XR 100mg last year combined with the 90mgs of Paxil I'm still on, and I've found a drastic improvement in my mood, anger and anxiety. My only complaint would be how sleepy it makes me in the mornings. A large coffee or a caffeinated beverage does the trick though and its worth the sleepiness to have some peace of mind."