high blood pressure
"I have been on losartan for 2 years now, to begin with 25mg then 50mg and shortly after 100mg. The lower dose caused no side effects but as soon as it was increased I started to become lethargic and depressive. My thighs, knees and back ached to the point where it was difficult to walk on occasions. There was no great improvement in my BP with the higher dose so I reduced the dose to 50mg by cutting the 100mg tablets in two and there has been an improvement in the symptoms but it's not perfect. Back to the doctor I guess."