bipolar disorde
"I've been taking Latuda for over a year now for bipolar 2.  It seemed to work well for a few months at 40mg, then stopped working.  Upped dose to 60, worked for a few months.  Increased again to 80, now ineffective.  Now I'm on lamotrigine concurrently - if that helps I will stop taking Latuda.

Side effects have been very bad.  Never had a panic attack in my life until I took Latuda, now I've had several.  Nausea every time I take it.  Supposedly this medicine is "weight-neutral", but I gained at least 30 pounds over the past year and a half (I didn't change my diet or exercise habits from before taking it).  Now I am eating better and working out, but I doubt if I can lose the weight until I'm off Latuda.  Hope to get off it soon!"