pain
"I have a form of muscular dystrophy and take this for my chronic severe pain. I've been on the immediate release 2x 50 mg a day. It is a miracle for me. I can function way better than I could on norco or oxy and it works way better for managing my pain than lesser pain killers like ultram. I've tried both the ER and IR and found the ER to not be as effective for me. 



nucynta IR has seriously given me more quality of life. The only downside for me is there is not yet a generic available and it's extremely expensive (even with insurance)."