abnormal uterine bleeding
"I have been on the Depo shot for 14 years, and it was a lifesaver for me. My doctor put me on it because I had PMS so bad, I could not live a normal life.  I have never had another period and no side effects.  I have not had a bone density test but would like to do so.  I just recently read that 2 years was all you should stay on it, I didn't know that before and was not told that by my doctor.  I think it's great."