abnormal uterine bleeding
"I went on DEPO a few years ago for about 1.5 years.  Before my cramps were so bad, I couldn't function for days. When I went on DEPO, it stopped my periods and cramping completely and drastically improved my quality of life. I went off the DEPO, because my fiance was stationed overseas and there was no point to be on it if he would not be around for a couple years. I went back on it in December 2015 a month before he was coming home. It was TERRIBLE!!!! I would have my period for 3 consecutive weeks. I would be good for 1 week and then it would start again. It was so frequent that I wouldn't even trust the week I didn't have it. I went off of it in December 2016. I will NEVER go back on DEPO"