pain
"I have been taking Nucynta for about three months and take only 2 x 50 mg tablets per day.  At first it worked very well with no side effects, except I felt euphoric and a bit sleepy. Therefore, I only took Nucynta at night.  But now in the mornings I notice that I wake up very depressed and unable to handle the day.  I do find that 1 plus hours of morning exercise helps me get over these feelings.  I believe I need to ween myself off of this medicine."