ibromyalgia
"A doctgor (I've been to many) tried me on Ultram.  On about the 2nd or 3rd day, I was at work and began feeling very strange.  I got shakier as the morning progressed.  I got up and could not walk without holding on to the wall.  Then I began having breathing problems.  I asked my boss if somebody could take me to the ER.  On the way there, I truly felt like I was going to die.  My coworker got me into the ER and the triage team first checked my heart out with an ECG, etc.  The conclusion the ER doctor came up with is that I was having something called Serotonin Syndrome which can be quite serious.  They gave me some Ativan and sent me home.  My mother-in-law was on Ultram for years and it worked very well for her."