depression
"I have been on Wellbutrin SR prescribed off label for major depressive disorder for about 3 years now.  Initially I had the same kind of side effects that are common such as headache, some anxiety and difficulty sleeping. The side effects diminished and pretty much went away after about a month, and I take my second dose at midday so that it doesn't impact my sleep.  
Overall, this medication has made a huge difference to my quality of life, and has stopped me experiencing cripplingly low moods and huge rapid mood swings and it continues to work as well now as it did at the start of treatment.  It has also helped me to focus and concentrate on a task in a way that I found hard before.
My main concern has been the impact on short term memory."