depression
"I was on venlafaxine and seroquel for about a year, and since it wasn't making much difference to my emotional state nor reducing suicidal ideation, my doctor removed the seroquel and replaced it with lithium. The first two weeks of being on it were possibly the worst two weeks of my life. In that time I slept no more than two hours a night, some nights not sleeping at all. I was incredibly suicidal and my skin all over my body itched. After that two weeks it seemed to flip like a switch and suddenly all I could do was sleep. I'm still on it a few months later and while the negative side effects have calmed down, I don't feel it has improved my mood at all. If anything it's made it flatter."