pain
"I was taking oxycontin 20   with oxycodone 15 for breakthrough qid for severe back pain/spinal stenosis. Previous surgery 30 years ago and no known surgery to help except the experimental approaches with cages to lift. I'm in the business so not interested. Anyway, knowing my pharmacology, I moved from oxycontin (4 hours half life to zohyrdro 8 hrs half life. And, its' spot on. Neither is a true BID drug but Zohydro comes close and gives you maybe 6-7 hours of good sleep and if you wake up with breakthrough, take an oxycodone, wait 45 minutesw and go back to bed. Don't take another zohydro. Fairly flexible. eally works well for me. So much better than force fitting a TID or even a QID oxycontin as a BID. Look at the pharmacodynamics please"