depression
"Like others, I have had good success with Ultracet (Tramadol with Acetaminophen) for pain, GAD and depression. A few weaknesses are 50% of the time I get a small headache. I experience tiredness/fatigue in the morning and lastly, there is the loss of well being when the drug wears off. This is part of the "dependency" (not addiction) that the user has to beware of.
But the drug takes the edge off pain, blows away depression for a bit and reduces anxiety. 
It's a balance of taking it when I need to but not all the time. It works for me."