epilepsy
"Before I came to the US I was taking other medications for epilepsy but upon dealing with a US doctor he recommended 2000 mg of Depakote daily. I immediately  went to the library and checked the side effects, which were considerable. I asked the doctor if I could take a smaller dose but he didn't think it wise. I decided to take matters into my own hands and reduce my dosage. I have been taking 250 mg now for 35 years with no seizures. Early on I found that when I took long flights to Asia and missed sleep and became dehydrated I would increase my dosage and then when I came back home I would slowly lower it again. I don't believe I am suffering from any side effects of this drug."