 Novartis AG NOVN, -0.84 on Thursday told investors that the Swiss drug maker plans to adopt a U.S.-first mindset in its bid to become a top-five player in the U.S. market by 2027. Novartis is one of the worlds largest pharmaceutical companies; however in the U.S., it was the tenth largest by revenue in the U.S. in 2021, according to FiercePharma. 