 Speaking on todays call will be our CEO and President, Dr. Rich Murray, who will discuss our pipeline progress and key milestones; followed by our CMO, Dr. Beth Trehu, who will provide an update on our clinical activities; and lastly, our CFO, Kim Drapkin, will review our first quarter financial results. Before we begin, I would like to remind everyone that todays discussion will include statements about our future expectations, plans and prospects that constitute forward-looking statements for the purposes of the safe harbor provisions under the Private Securities Litigation Reform Act of 1995. 