 GlycoMimetics, Inc. Nasdaq: GLYC today announced that important new preclinical data on the mechanism of action for its late-stage clinical candidate, uproleselan, are published in the April 27, 2020, issue of Nature Communications. The paper outlines how uproleselan, an investigational, first-in-class, targeted inhibitor of E-selectin, can reduce chemoresistance in acute myeloid leukemia AML through the key mechanism of targeted E-selectin inhibition.1 