 NEW YORK and VIENNA, Austria, Aug. 03, 2020 GLOBE NEWSWIRE -- HOOKIPA Pharma Inc. NASDAQ: HOOK, HOOKIPA, a company developing a new class of immunotherapeutics targeting infectious diseases and cancers, today announced that both the United States Patent and Trademark Office USPTO and the European Patent Office EPO have issued patents covering HOOKIPAs proprietary replicating arenavirus technology TheraT. The patents US Patent No. 10,722,564 and European Patent No. 3218504 are granted to the University of Geneva. HOOKIPA has exclusively licensed these patents from the University. The patent claims cover current product candidates based on HOOKIPAs replicating arenavirus platform technology TheraT, including the Companys lead oncology product candidates HB-201 and HB-202. These programs are currently in clinical development for the treatment of Human Papillomavirus 16-positive HPV16 cancers.In addition to the replicating arenavirus platform patents, the USPTO recently granted a patent US Patent No. 10,669,315 specifically related to HOOKIPAs HB-201 and HB-202 product candidates, which are two different replicating arenavirus-based vectors encoding the same E7E6 fusion protein. The patent protection for HB-201 and HB-202 conferred by these platform and product-specific patents extends to 2037 in the United States and 2035 in Europe not taking into account potential Patent Term Extension or Supplementary Protection Certificates.The newly issued patents provide general, long-term patent protection for our arenavirus technology and related oncology programs. The combination of broad patents on our arenavirus platform and specific patents on product candidates underpin the commercial potential of the therapies we are developing, said Joern Aldag, HOOKIPAs Chief Executive Officer.About Replicating Arenavirus Technology TheraT HOOKIPAs proprietary and patented replicating arenavirus technology induces powerful immune responses. HOOKIPAs replicating arenavirus constructs are engineered to be specific for antigens of choice. Arenaviruses have a natural ability to evade neutralization, enabling repeated intravenous delivery.The replicating arenavirus platform is able to direct more than 50 of a mouses T cells to focus on a single target of choice. In various animal models, immunization with HOOKIPAs replicating arenavirus resulted in elimination of a primary tumor and metastasis and provided long-term protection against a cancer re-challenge months after primary treatment. The Company believes that its arenavirus-based treatments are more potent immunotherapies than alternative therapeutic modalities.HOOKIPAs lead oncology programs, HB-201 and HB-202 for the treatment of Human Papillomavirus 16-positive cancers, are both based on its replicating arenavirus platform.About HOOKIPA HOOKIPA Pharma Inc. NASDAQ: HOOK is a clinical stage biopharmaceutical company developing a new class of immunotherapeutics targeting infectious diseases and cancers based on its proprietary arenavirus platform that reprograms the bodys immune system.HOOKIPAs proprietary arenavirus-based technologies, non-replicating VaxWave and replicating TheraT, induce robust antigen-specific CD8 T cells and pathogen-neutralizing antibodies. HOOKIPAs off-the-shelf viral vectors target antigen presenting cells in vivo to activate the immune system. Both technologies enable repeat administration to augment and refresh immune responses. As a monotherapy, our replicating arenavirus technology has the potential to induce CD8 T cell response levels previously not achieved by other immuno-therapy approaches.HOOKIPAs non-replicating prophylactic Cytomegalovirus CMV vaccine candidate is currently in a Phase 2 clinical trial for patients awaiting kidney transplantation. To expand its infectious disease portfolio, HOOKIPA entered into a collaboration and licensing agreement with Gilead Sciences, Inc. to research arenavirus-based functional cures for HIV and chronic Hepatitis B infections.In addition, HOOKIPA is building a proprietary immuno-oncology pipeline by targeting virally mediated cancer antigens, self-antigens and next-generation antigens. The lead replicating arenavirus oncology product candidates, HB-201 and HB-202, are in development for the treatment of Human Papilloma Virus 16-positive cancers. The Phase 12 clinical trial for HB-201 was initiated in December 2019. The HB-202 IND application was cleared by the FDA in June 2020.Find out more about HOOKIPA online at Forward Looking StatementsCertain statements set forth in this press release constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements can be identified by terms such as believes, expects, plans, potential, would or similar expressions and the negative of those terms. Such forward-looking statements involve substantial risks and uncertainties that could cause HOOKIPAs research and clinical development programs, future results, performance or achievements to differ significantly from those expressed or implied by the forward-looking statements. Such risks and uncertainties include, among others, the uncertainties inherent in the drug development process, including HOOKIPAs programs early stage of development, the process of designing and conducting preclinical and clinical trials, the regulatory approval processes, the timing of regulatory filings, the challenges associated with manufacturing drug products, HOOKIPAs ability to successfully establish, protect and defend its intellectual property, risks relating to business interruptions resulting from the coronavirus COVID-19 disease outbreak or similar public health crises, the impact of COVID-19 on the enrollment of patients and timing of clinical results for HB-101 and other programs, and other matters that could affect the sufficiency of existing cash to fund operations and HOOKIPAs ability to achieve the milestones under the agreement with Gilead. HOOKIPA undertakes no obligation to update or revise any forward-looking statements. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to the business of the company in general, see HOOKIPAs quarterly report on Form 10-Q for the quarter ended March 31, 2020 which is available on the Security and Exchange Commissions website at and HOOKIPAs website at Investors and others should note that we announce material financial information to our investors using our investor relations website SEC filings, press releases, public conference calls and webcasts. We use these channels, as well as social media, to communicate with our members and the public about our company, our services and other issues. It is possible that the information we post on social media could be deemed to be material information. Therefore, we encourage investors, the media, and others interested in our company to review the information we post on the U.S. social media channels listed on our investor relations website.For further information, please contact:MediaInvestors Nina WaibelMatt Beck Senior Director - CommunicationsExecutive Director - Investor Relations Media enquiries Instinctif Partners 44 020 7457 2020 