 Ironwood Pharmaceuticals NASDAQ:IRWD and BIOFRONTERA AGADR NASDAQ:BFRA are both small-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their earnings, valuation, dividends, profitability, risk, analyst recommendations and institutional ownership. Profitability This table compares Ironwood Pharmaceuticals and BIOFRONTERA AGADRs net margins, return on equity and ... 