 Ampio Pharmaceuticals Inc NYSEAMERICAN:AMPE gapped up prior to trading on Friday . The stock had previously closed at 0.33, but opened at 0.57. Ampio Pharmaceuticals shares last traded at 0.57, with a volume of 3,610,200 shares changing hands. Separately, Zacks Investment Research cut shares of Ampio Pharmaceuticals from a buy rating to a hold rating ... 