 Shares of Anthem Inc. ANTM, -2.30 were indicated down more than 2 in premarket trading Wednesday, after the health insurer reported fourth-quarter profit and revenue that rose above expectations while premiums missed, and provided a somewhat downbeat full-year outlook. Net income more than doubled to 1.13 billion, or 4.63 a share, from 551 million, or 2.19 a share, in the year-ago period. 