 Heres a roundup of top developments in the biotech space over the last 24 hours:Scaling The Peaks Biotech stocks that hit 52-week highs on May 20. ADC Therapeutics SA NYSE: ADCT went public May 15 Allogene Therapeutics Inc NASDAQ: ALLO Ascendis Pharma AS NASDAQ: ASND announced first-quarter results Altimmune Inc NASDAQ: ALT Biondvax Pharmaceuticals Ltd - ADR NASDAQ: BVXV Cue Biopharma Inc NASDAQ: CUE reacted to first-quarter results Evoke Pharma Inc NASDAQ: EVOK announced FDAs conditional approval for the brand name Gimoti for its nasal spray product candidate for the relief of symptoms in adult women with acute and recurrent diabetic gastroparesis GENMAB ASS ADR NASDAQ: GMAB I-Mab ADR NASDAQ: IMAB Immunomedics, Inc. NASDAQ: IMMU Intellia Therapeutics Inc NASDAQ: NTLA Novo Nordisk AS NYSE: NVO PDL BioPharma Inc NASDAQ: PDLI Pulmatrix Inc NASDAQ: PULM Qiagen NV NYSE: QGEN Soleno Therapeutics Inc NASDAQ: SLNO Surface Oncology Inc NASDAQ: SURF - announced an oncology partnership with Merck Co., Inc. NYSE: MRK VBI Vaccines Inc NASDAQ: VBIV Zentalis Pharmaceuticals Inc NASDAQ: ZNTL announced 20-million Series A financing to establish a Chinese joint ventureDown In The Dumps Biotech stocks that hit 52-week lows on May 20. Genfit SA NASDAQ: GNFT RA Medical Systems Inc NYSE: RMED priced its 22.22-million-share common stock offering at 45 cents per shareStocks In Focus Gilead-Galapagos Drug Produces Mixed Results In Ulcerative Colitis Study Gilead Sciences, Inc. NASDAQ: GILD and GALAPAGOS NVS ADR NASDAQ: GLPG announced top-line results from the Phase 2b3 trial evaluating the efficacy and safety of filgotinib in adult patients with moderately to severely active ulcerative colitis showing mixed results.The topline data showed that filgotinib 200 mg achieved all primary endpoints in the study, inducing clinical remission at week 10 and maintaining clinical remission at week 58 in a significantly higher proportion of patients compared with placebo, while the 100mg dose did not achieve statistically significant clinical remission at week 10.Gilead shares were down 1.07 at 73.10 in Thursdays premarket session, while Galapagos shares were down 5.98 at 208.04. Entera Bio Reports Positive Results For Midstage Study Of Osteoporosis Drug Entera Bio Ltd NASDAQ: ENTX announced interim limited biomarker data from the ongoing Phase 2 clinical trial of EB613 in osteoporosis patients, with the study demonstrating statistically significant effects on the P1NP biomarker after one month of treatment as compared to placebo, and meaningful increases at months two and three as compared to placebo with the highest EB613 dose of 1.5mg.Based on the favorable safety profile for patients on EB613 in the ongoing Phase 2 study, the company said it intends to evaluate additional doses greater than 1.5mg to advance into a potential Phase 3 study, if appropriate.The company reported first-quarter results, posting revenue of 42,000 solely from RD; services provided to Amgen, Inc. NASDAQ: AMGN versus no revenue in the year-ago quarter. The loss per share narrowed from 26 cents to 16 cents.The stock was down 12.28 at 2.50 in the premarket session. Hepions NASH Drug Found Safe Enough To Advance Testing To Fourth Dose Level In Early Stage Study Hepion Pharmaceuticals Inc NASDAQ: HEPA announced the advancement to the fourth dose level in its ongoing Phase 1b multiple ascending dose study of CRV431.The open-label MAD study is designed to assess the safety, tolerability and pharmacokinetics of CRV431 administered orally to healthy volunteers once daily for 28 days.With the study having assessed the 75mg, 150mg and 225mg doses, the Clinical Trial Management team has reviewed the 225mg cohort data and determined this dosing level to be safe and well-tolerated, authorizing advancement to the next dosing level of 300mg daily for 28 days.The stock was up 7.07 at 1.97 premarket.View more earnings on IBBSee also: The Week Ahead In Biotech: Aquestive Awaits FDA Decision, Earnings Flow Slows Catalent To Acquire New Clinical Packaging Facility In Japan Catalent Inc NYSE: CTLT, a CDMO, announced a deal to acquire a clinical packaging facility in Minakuchi, located in the Shiga prefecture of Japan, from Teva-Takeda Pharmaceuticals. This purchase will establish a new clinical GMP manufacturing and distribution hub to support clinical studies. The deal is expected to close July 1. The companies did not disclose the financial terms of the deal.West Pharma To Join SP; 500 Index West Pharmaceutical Services Inc. NYSE: WST said its shares have been selected to join the SP; 500 Index effective after the close of trading Thursday.Synlogic Terminates Inflammatory Bowel Disease Drug Development Deal With AbbVie Synlogic Inc NASDAQ: SYBX announced the termination of its collaboration with AbbVie Inc NYSE: ABBV for the development of synthetic biotic medicines for the potential treatment of inflammatory bowel disease.Upon termination, Synlogic regains all rights to develop these and new IBD Synthetic Biotic medicines for all effectors targeting IBD.Akorn To File For Chapter 11 Bankruptcy Akorn, Inc. NASDAQ: AKRX said it and its U.S. subsidiaries filed for Chapter 11 bankruptcy protection to execute an in-court sale of its business while addressing litigation-related overhangs and best positioning the business for long-term success under new ownership.In connection with the filing, the company said it has executed a restructuring support agreement with lenders representing more than 80 of its secured debt that will collectively serve as a stalking horse bidder in the companys sale process and provide additional liquidity to fund the companys business operations during this process.The stock was plunging 26.08 at 21 cents in the premarket session.FibroGen-Astellas Anemia Drug Accepted For Regulatory Review In Europe FibroGen Inc NASDAQ: FGEN and ASTELLAS PHARMAADR OTC: ALPMY said the marketing authorization application for roxadustat for the treatment of anemia in adult patients with chronic kidney disease has been accepted by the European Medicines Agency for regulatory review.Offerings Flexion Therapeutics Inc NASDAQ: FLXN said it has commenced an underwritten public offering of 75 million in shares of its common stock.The stock was slipping 5.68 at 10.30 in the premarket session. Boston Scientific Corporation NYSE: BSX said it has commenced concurrent offerings of 750 million in shares of its common stock and 750 million of shares of its Series A Mandatory Convertible Preferred Stock.The stock was down 3.17 at 36 premarket. Scpharmaceuticals Inc NASDAQ: SCPH priced an underwritten public offering of 5.78 million shares at 8.65 each to raise gross proceeds of 50 million. All the shares are being offered by the company. The offering is expected to close May 26.In premarket trading, Scpharmaceuticals shares were down 16.81 at 9.01. On The RadarPDUFA Dates The FDA is due to rule on Aquestive Therapeutics Incs NASDAQ: AQST NDA for apomorphine sublingual film APL-130277, which is being evaluated for treating off episodes in Parkinsons disease patients. APL-130277 is being developed by Sunovion Pharmaceuticals, a subsidiary of Sumitomo Dainippon Pharma, and it is being evaluated in partnership with Aquestive.Earnings Medtronic PLC NYSE: MDT before the market open PAVmed Inc NASDAQ: PAVM after the close Xenon Pharmaceuticals Inc NASDAQ: XENE after the closeRelated Link: These 6 Coronavirus Vaccine Candidates Are The Likeliest To Succeed, Says Morgan Stanley See more from Benzinga The Daily Biotech Pulse: Aldeyra Jumps Into COVID-19 Drug Fray, FDA Nod For Myriads Companion Diagnostic Test The Daily Biotech Pulse: FDA Nod For Roche, Arbutus Releases Positive Readout For HBV Therapy, Moderna Announces .34B Common Stock OfferingC 2020 Benzinga.com. Benzinga does not provide investment advice. All rights reserved. 