 Sema4 Holdings Corp NASDAQ: SMFR has agreed to acquire OPKO Health Incs NASDAQ: OPK wholly-owned subsidiary, GeneDx Inc, for approximately 623 million. Sema4 will acquire GeneDx for an upfront payment of 150 million in cash plus 80 million shares in Sema4, with up to an additional 150 million revenue-based milestones over the next two years. 