<prompt> Translate the following text to EnglishMapendekezo ya 4 - Utafiti unahitajika ili kutathmini athari za kisheria, faragha, usiri, udhibiti, na masuala ya binadamu juu ya uchunguzi na uingiliaji kwa matatizo ya pombe kati ya wagonjwa wa ED.  <response>: Recommendation 4 Research is needed to evaluate the effects of legal, privacy, confidentiality, regulatory, and human subjects issues on screening and interventions for alcohol problems among ED patients. 