<prompt> Translate the following text to EnglishMabadiliko ya kwanza yalikuwa mabadiliko ya maelezo ya swali la utafiti kutoka kwa mtafiti mkuu wakati wa kipindi cha utendaji wa utafiti kwa watu waliopewa utafiti kabla ya ukusanyaji wa data.  <response>: The first adaptation was a shift of the specification of study question from the principal investigator during the period of study performance to the persons who commissioned the study in advance of data collection. 