<prompt> Translate the following text to EnglishHii ilikuwa hasa kesi baada ya kujikuta kwenye njia ya kusini iliyochukuliwa na wafanyabiashara na wamishonari wa Ulaya wa karne ya 16.  <response>: This was especially the case after it found itself on the southern route taken by European merchants and missionaries of the 16th century. 