<prompt> Translate the following text to EnglishMakadirio ya msingi yanategemea tafsiri yetu ya sasa ya fasihi ya kisayansi na kiuchumi, hukumu zake kuhusu data bora zinazopatikana, mifano, na mbinu za kuunda, na dhana ambazo zinaona ni sahihi zaidi kupitisha katika uso wa kutokuwa na uhakika muhimu.  <response>: The Base Estimate is based on our current interpretation of the scientific and economic literature; its judgments regarding the best available data, models, and modeling methodologies; and the assumptions it considers most appropriate to adopt in the face of important uncertainties. 