<prompt> Translate the following text to EnglishKwa mujibu wa Shirika la Afya na Usalama, gharama za jumla za mwaka wa mwaka wa sheria hiyo, ikiwa ni pamoja na hasara na faida, zitafikia jumla ya dola 52.  <response>: FDA estimates that the aggregated net annualized costs of the rule, accounting for both losses and gains, will total 52. 