<prompt> Translate the following text to EnglishKuna vikwazo vikubwa kwa uchunguzi, na utafiti wa vitendo juu ya utekelezaji wa uchunguzi, motisha, ufanisi, na uwezo wake wa kufikia idadi kubwa ya watu kwa gharama ya chini ni muhimu.  <response>: There are large obstacles to screening, and practical research on screening implementation, incentives, efficiency, and its ability to reach large numbers of people at low cost is necessary. 