<prompt> Answer this question truthfullyWhat is the specific tumor suppressor gene that is commonly associated with the development of Breast, Prostate, Endometrial Cancer, and Cowden Syndrome when mutations occur?  <response>: <reason> Mutations in the PTEN Phosphatase and Tensin Homolog gene are commonly associated with the development of Breast, Prostate, Endometrial Cancer, and Cowden Syndrome. 