<prompt> Answer this question truthfullyWhat disease is characterized by a starry sky appearance on histology, a large jaw lesion, and swelling associated with EBV?  <response>: <reason> Endemic African Burkitt Lymphoma is characterized by a starry sky appearance on histology, a large jaw lesion, and swelling associated with EBV.Endemic African Burkitt Lymphoma is a type of non-Hodgkin lymphoma that is commonly found in children in sub-Saharan Africa. It is caused by the Epstein-Barr virus EBV and is characterized by a rapidly growing tumor that often affects the jaw.The starry sky appearance on histology is due to the high number of rapidly dividing tumor cells, which are interspersed with macrophages that phagocytose the cell debris. The tumor cells have a characteristic medium-sized appearance on histology.In addition to the jaw lesion, Endemic African Burkitt Lymphoma can also affect other organs such as the abdomen, ovaries, and testes. The disease can be fatal if left untreated, but it is highly responsive to chemotherapy.Endemic African Burkitt Lymphoma is different from the sporadic form of Burkitt Lymphoma, which is more commonly found in other parts of the world and is not associated with EBV. 