<prompt> Answer this question truthfullyWhat is the initial response of p53 to DNA damage and what enzymes does it facilitate the activity of? Bonus: What does p53 induce that inhibits the cell cycle?  <response>: <reason> In response to DNA damage, p53 initially attempts to halt the cell cycle and facilitates the activity of DNA repair enzymes. Bonus: p53 induces the expression of p21, which inhibits the cell cycle. 