<prompt> Answer this question truthfullyHow is acute leukemia defined in terms of the percentage of blasts in the bone marrowblood, and what is the consequence of this neoplastic proliferation?  <response>: <reason> Acute leukemia is defined as a neoplastic proliferation of blasts greater than 20 in the bone marrowblood, which crowds out other cells from the marrow and leads to bone marrow failure. 