<prompt> Answer this question truthfullyWhat are some of the ways in which ethanol can contribute to carcinogenic activity?  <response>: <reason> What are some of the ways in which ethanol can contribute to carcinogenic activity? Ethanol has many methods of carcinogenic activity including: 1 - metabolites forming DNA adducts 2 - depletion of S-adenosylmethionine SAM 3 - stimulating the Epithelial-Mesenchymal Transition. 