<prompt> Answer this question truthfullyWhat is the mechanism by which glucagon, catecholamines, and glucocorticoids induce insulin resistance, and what residues of the insulin receptor and IRS-1 are involved in this process?  <response>: <reason> Glucagon, catecholamines, and glucocorticoids induce insulin resistance by activating kinases that phosphorylate serinethreonine residues of the insulin receptor and IRS-1. 