<prompt> Answer this question truthfullyWhat is the effect of Huntingtons disease on GABA levels?  <response>: <reason> Huntingtons disease is a neurodegenerative disorder that is caused by a mutation in the huntingtin gene. One of the key features of the disease is the progressive loss of neurons in the brain, particularly in the basal ganglia, which is involved in movement control. This loss of neurons can lead to changes in GABA levels in the brain. Specifically, Huntingtons disease is characterized by decreased GABA levels in certain areas of the brain, such as the striatum, which can contribute to the abnormal movements chorea and other symptoms of the disease. Understanding the changes in GABA levels associated with Huntingtons disease is important for developing effective treatments for the disorder. 