<prompt> Answer this question truthfullyWhat is the mechanism of action of evolocumab in relation to PCSK9 and hepatic LDL receptors?  <response>: <reason> What is the mechanism of action of evolocumab in relation to PCSK9 and hepatic LDL receptors? Evolocumab binds PCSK9 and prevents degradation of hepatic LDL receptors. 