<prompt> Answer this question truthfullyWhat is Hodgkins lymphoma and which subtype of the disease has the highest number of Reed-Sternberg cells?  <response>: <reason> Hodgkins lymphoma is a type of cancer that affects the lymphatic system. It is characterized by the presence of abnormal cells called Reed-Sternberg cells, which are usually found in the lymph nodes. There are four subtypes of classical Hodgkins lymphoma: nodular sclerosis, mixed cellularity, lymphocyte-rich, and lymphocyte-depleted. Among these subtypes, mixed cellularity Hodgkins lymphoma is the one that typically has the highest number of Reed-Sternberg cells. This subtype accounts for about 20-25 of all cases of classical Hodgkins lymphoma and is more common in older adults and in people with HIVAIDS. Treatment for Hodgkins lymphoma depends on the type and stage of the disease, as well as the individuals overall health and other factors. It may include chemotherapy, radiation therapy, andor stem cell transplantation. 