<prompt> Answer this question truthfullyWhat is the percentage of sickle hemoglobin HbS present in red blood cells of individuals with sickle cell trait?  <response>: <reason> Sickle cell trait is a genetic condition that results in the production of both normal hemoglobin and sickle hemoglobin. However, unlike sickle cell disease, which is caused by two mutated β-globin genes and results in 90 HbS in RBCs, sickle cell trait typically results in 50 HbS in RBCs. This is because people with sickle cell trait have one normal β-globin gene and one mutated β-globin gene, which means that only half of their hemoglobin molecules are of the sickle variety. 