<prompt> Answer this question truthfullyWhat are the exclusion criteria for IV tPA?  <response>: <reason> What are the exclusion criteria for IV tPA? The exclusion criteria for IV tPA include: National Institute of Health Stroke Scale NIHSS score 5 indicating minor or no stroke symptoms or 25 severe stroke, involvement of 13rd MCA territory, another recent strokehead injury in the preceding 3 months, major surgery in the last 14 days, significant hypertension e.g. systolic 185, diastolic 100, INR 1.6, and platelets 100k. 