<prompt> Answer this question truthfullyWhat is the relationship between melanocyte-stimulating hormone MSH and POMCACTH levels, and what clinical manifestation may occur as a result of increased POMCACTH levels?  <response>: <reason> Melanocyte-stimulating hormone MSH is found in POMC and its fragments, thus, increased levels of POMC and ACTH may lead to skinmucosal pigmentation e.g. Addison disease. 