<prompt> Answer this question truthfullyWhat is the enzyme that needs to be replaced in Enzyme Replacement Therapy for the treatment of Hurler Syndrome?  <response>: <reason> Enzyme Replacement Therapy is a medical treatment that involves replacing a missing or deficient enzyme in a patients body. In the case of Hurler Syndrome, Enzyme Replacement Therapy requires replacement of alpha-L-iduronidase. Hurler Syndrome is a rare genetic disorder that affects the bodys ability to break down certain sugars, leading to the buildup of harmful substances in the bodys cells and tissues. Enzyme Replacement Therapy can help to reduce the buildup of these substances and improve symptoms in patients with Hurler Syndrome. Enzyme Replacement Therapy is a promising approach for the treatment of many other genetic disorders as well, and ongoing research is focused on developing new therapies for these conditions. 