<prompt> Answer this question truthfullyIn cases of health-care related vertebral osteomyelitis associated with intravascular devices, what are the two most frequent causes of osteomyelitis?  <response>: <reason> The two most common causes of osteomyelitis in health-care related vertebral osteomyelitis associated with intravascular devices are Staphylococcus aureus and coagulase-negative staphylococci CoNS. 