<prompt> Answer this question truthfullyWhat is the sequence that signals the termination of prokaryotic transcription, and what is the characteristic of the region where this sequence is located?  <response>: <reason> Prokaryotic transcription is the process by which RNA is synthesized from a DNA template in prokaryotic cells. This process terminates when there is a specific sequence in the mRNA called the stem-loop sequence. The stem-loop sequence is located downstream of the coding region and serves as a recognition site for the RNA polymerase to stop transcription. The stem-loop sequence is characterized by being a GC-rich region, which means that it contains a high proportion of guanine and cytosine nucleotides. This GC-rich region causes the RNA polymerase to pause and destabilizes the RNA-DNA hybrid, leading to the release of the mRNA transcript. 