<prompt> Answer this question truthfullyWhat is Meltzers triad, and what condition is it highly suggestive of when seen in conjunction with increased serum concentration of polyclonal IgG and IgM?  <response>: <reason> Meltzers triad purpura, arthralgia, and fatigue with increased serum concentration of polyclonal IgG and IgM is highly suggestive of mixed cryoglobulinemia. 