<prompt> Answer this question truthfullyHow does the loss of membrane blebs in hereditary spherocytosis affect the shape of red blood cells RBCs?  <response>: <reason> The loss of membrane blebs in hereditary spherocytosis renders RBCs round spherocytes instead of their normal disc-shaped morphology. This change in shape can affect the ability of the RBCs to function properly, leading to anemia and other complications. 