<prompt> Answer this question truthfullyWhat is Lobular carcinoma in situ LCIS, and what is the specific characteristic of this non-invasive breast cancer that is due to the lack of a particular protein?  <response>: <reason> Lobular carcinoma in situ LCIS is a non-invasive breast cancer that is characterized by dyscohesive cells due to the lack of E-cadherin protein. 