<prompt> Answer this question truthfullyWhat is the adaptive response in NH3 synthesis in the cells of the proximal tubule during chronic acidosis?  <response>: <reason> In chronic acidosis, there is an adaptive increase in NH3 synthesis in the cells of the proximal tubule. Chronic acidosis is a condition in which there is an excess of acid in the blood, which can occur due to a variety of underlying conditions such as kidney disease or diabetes. The proximal tubule is a part of the nephron in the kidney that is responsible for reabsorbing nutrients and regulating acid-base balance. In chronic acidosis, the cells in the proximal tubule respond by increasing the synthesis of ammonia NH3, which can act as a buffer to help neutralize the excess acid in the blood. This adaptive response is an important mechanism by which the body can maintain acid-base balance, and it is just one example of the complex physiological processes that occur in response to changes in the bodys internal environment. 