<prompt> Answer this question truthfullyWhat are the brain lesions that can restrict diffusion, and which specific lesions are associated with supratentorial, CPA, and temporal horn locations?  <response>: <reason> Restricted diffusion lesions, which appear brighthyperintense on DWI and have corresponding low signal on ADC, can be caused by a variety of brain lesions. These include bacterial pyogenic abscesses with a central cavity, primary CNS lymphoma, GBM if crossing midline, medulloblastoma, epidermoid cysts, CJD if cortical, herpes encephalitis in temporal horns, xanthogranuloma in choroid plexus, cholesteatoma, and acute wallerian degeneration of corticospinal tracts. Supratentorial lesions are most commonly associated with abscesses or lymphomas, while CPA lesions are often epidermoid cysts that occur in the basal cisterns, with the cerebellopontine anglecistern being the most common location. Lesions in the temporal lobes are often caused by herpes encephalitis. 