<prompt> Answer this question truthfullyWhat is the process by which norepinephrine is converted to epinephrine, and what is the role of the enzyme phenylethanolamine-N-methyltransferase and the cofactor S-adenosylmethionine SAM in this process? Additionally, what hormone stimulates this conversion?  <response>: <reason> The process by which norepinephrine is converted to epinephrine involves the enzyme phenylethanolamine-N-methyltransferase with S-adenosylmethionine SAM as a cofactor. This conversion is stimulated by cortisol. 