<prompt> Answer this question truthfullyWhat are the four drug classes that are commonly used in the treatment of primary uncomplicated hypertension in patients who are NOT African American?  <response>: <reason> The four drug classes that are commonly used in the treatment of primary uncomplicated hypertension in patients who are NOT African American are thiazide diuretics, ACE inhibitors, angiotensin receptor blockers ARBs, and dihydropyridine calcium channel blockers CCBs. 