<prompt> Answer this question truthfullyWhat are the causes of endothelial cell contraction that lead to swelling in inflammation, in addition to endothelial cell disruption due to tissue damage?  <response>: <reason> The causes of endothelial cell contraction that lead to swelling in inflammation, in addition to endothelial cell disruption due to tissue damage, are leukotrienes, histamine, and serotonin. 