<prompt> Answer this question truthfullyWhat is the underlying disease process or mechanism that causes papillary thyroid cancer?  <response>: <reason> Papillary thyroid cancer may be positive for following markers: TTF-1 Thyroglobulin Thyroid peroxidase CD56 NCAM PAX8 HBME-1 CITED1 Cytokeratin 19 Galectin 3 These markers are helpful in the confirmation of thyroid origin of the tumor particularly when the tumor is outside of the thyroid gland. 