<prompt> Answer this question truthfullyWhat is the importance of malignancy in hematological disorders?  <response>: <reason> For the analysis of a suspected hematological malignancy, a complete blood count and blood film are essential, as malignant cells can show in characteristic ways on light microscopy. When there is lymphadenopathy, a biopsy from a lymph node is generally undertaken surgically. In general, a bone marrow biopsy is part of the work up for the analysis of these diseases. All specimens are examined microscopically to determine the nature of the malignancy. A number of these diseases can now be classified by cytogenetics AML, CML or immunophenotyping lymphoma, myeloma, CLL of the malignant cells. 