<prompt> Answer this question truthfullyWhat is the significance of senile amyloidosis when conducting a physical examination in a wild-type individual?  <response>: <reason> Physical examination of patients with wild-type senile amyloidosis can be significant for the condition in question and can also translate the variety of pathologies as a part of aging and age-related comorbidities.Patients with wild-type senile amyloidosis appear senile. Exact appearance of the patients depend upon the severity of the condition.Hypertension TachycardiaEdemaHEENT examination of patients with wild-type senile amyloidosis is usually normal.Elevated jugular pressure Pulmonary examination of patients with wild-type senile amyloidosis is usually normal.Third heart sound Fourth heart sound Arrhythmias Auscultation may also reveal rales, heart murmurs, andor other pathologic heart sounds. In patients with valvular heart disease involvement, murmurs of mitral and tricuspid regurgitation may be heard.Hepatomegaly may be present in the setting of right heart failure Ascites may be present in the setting of right heart failure Splenomegaly is rareBack examination of patients with wild-type senile amyloidosis is usually normal.Genitourinary examination of patients with wild-type senile amyloidosis is usually normal.Peripheral neuropathyPeripheral edema 