<prompt> Answer this question truthfullyWhat is the effect of cerebral venous sinus thrombosis?  <response>: <reason> There are more than 100 different causes of cerebral venous sinus thrombosis CVT. Virchows principles blood stasis, modification of vascular wall, and blood rheology should be used to identify all the predisposing conditions for CVT. There are also some genetic and acquired causes leading to CVT. In the cohort of an International study of cerebral vein and dural sinus thrombosis ISCVT, 34 of patients had thrombophilia while 22 of them had acquired thrombophilia. Genetic prothrombotic causes - Antithrombin deficiency- Protein C and S deficiency- Factor v Leiden mutation- Resistance to activated protein C- prothrombin mutation AG at position 20210- mutations leading to homocysteinemia- methylenetetrahydrofolate reductase MTHFRAcquired Prothrombotic States - pregnancy- puerperium- homocysteinemia- antiphospholipid antibody- nephrotic syndromeInfection - meningitis- otitis- mastoiditis- sinusitis- neck, face, mouth infection- systemic infectious diseases- AIDSInflammatory Autoimmune Diseases - systemic lupus erythematosus- Adamantiades- Behçet disease- Wegener granulomatosis- sarcoidosis- inflammatory bowel disease- thromboangiitis obliteransHematology - polycythemia- thrombotic thrombocytopenic purpura- thrombocythemia- severe anemia and autoimmune hemolytic anemia- paroxysmal nocturnal hemoglobinuria- heparin-induced thrombocytopeniaDrugs - oral contraceptives- lithium, androgens- sumatriptan- intravenous immunoglobulin- hormone replacement therapy- asparaginase- steroids- illicit drugs such as ecstasyMechanical Causes - head trauma- neurosurgical procedures- jugular vein catheterization- lumbar puncture- injury to cerebral sinuses- intravenous drug abuseMalignancy - CNS tumors- systemic malignancies-solid tumors outside CNSOther Causes - dehydration, especially in children- toxicosis- arteriovenous malformations- dural fistulae- congenital heart disease- post radiation 