<prompt> Answer this question truthfullyCan you provide detailed information about Alendronate?  <response>: <reason> Acute inflammations of the gastrointestinal tract esophagitis, gastritis, ulcerations Clinically manifest osteomalacia Certain malformations and malfunctions of the esophagus strictures, achalasia Inability to stand, walk, or sit for 30 minutes after oral administration Renal impairment with a creatinine clearance below 30mlmin Hypersensitivity to alendronate or another ingredient Hypocalcemia Pregnancy and breastfeeding Patients below 18 yrs. of age, because no clinical data exists 