<prompt> Answer this question truthfullyCould you explain what Turcot syndrome is?  <response>: <reason> Turcot syndrome is the association between familial adenomatous polyposis and brain tumors like medulloblastoma, malignant glioma. It was first reported by Canadian surgeon Jacques Turcot 1914- et al in 1959 and hence carries the first authors name. The genetic basis of Turcot syndrome is uncertain.The gene most likely to be involved is APC gene in chromosome 5q. However, the syndrome has been claimed to be linked to various mutations in a number of genes. For example, the mismatch repair genes MLH1 Online Mendelian Inheritance in Man OMIM 120436 or PMS2 Online Mendelian Inheritance in Man OMIM 600259. 