<prompt> Answer this question truthfullyWhat are the effects of systemic lupus erythematosus?  <response>: <reason> Genetic predisposition: HLA class polymorphism Complement genes Female sexual gene due to high levels of estrogen and prolactin Auto-immune disease Infections Parvovirus B19 Epstein-Barr virus EBV Trypanosomiasis Mycobacterial infectionsExposure to ultraviolet UV light Can exacerbate or induce systemic manifestations of SLE Drug-induced lupus 