<prompt> Answer this question truthfullyCan you provide an explanation for YK and drainage?  <response>: <reason> The mainstay of therapy for pyogenic liver abscesses is percutaneous drainage and antimicrobial therapy. Empiric therapy for pyogenic liver abscesses consists of either a second- or third-generation cephalosporin with metronidazole or piperacillin-tazobactam. Amebic liver abscesses are often treated medically with a short course of metronidazole or tinidazole followed by 20 days of iodoquinol. 