<prompt> Answer this question truthfullyWhat are the symptoms and history of Peutz-Jeghers syndrome?  <response>: <reason> The hallmark of Peutz-Jeghers syndrome is hamatomatous polyps. A positive history of mucucutaneous hyperpigmentation and rectal bleeding is suggestive of Peutz-Jeghers syndrome. The most common symptoms of Peutz-Jeghers syndrome include abdominal pain, fatigue, and weight loss. 