<prompt> Answer this question truthfullyWhat are the laboratory findings associated with anemia in chronic diseases?  <response>: <reason> General Mild normocytic and normochromic anemia with a hemoglobin concentration of 10 to 11 gdL Microcytic and hypochromic anemia with a mean corpuscular volume MCV less than 70 fL in less than 25 percent of the cases Normal or low mean corpuscular hemoglobin MHC similar to the MCV Normal to increased red cell distribution width RDW No significant changes in the mean corpuscular hemoglobin concentration MCHC Severe anemia, with a hemoglobin concentration 8 gdL in 20 percent of cases Low absolute reticulocyte count 25,000microL in many cases Elevation in cytokines e.g. IL-6, interferon-gamma Elevation in acute phase reactants e.g., fibrinogen, erythrocyte sedimentation rate, C-reactive protein, ferritin, haptoglobin, factor VIIIIron studiesLow serum iron concentration and transferrin level also measured as total iron binding capacity, TIBC Normal or low-normal percent saturation of transferrin TSAT Normal or elevated serum ferritin concentrationSoluble transferrin receptor studies sTfR is normal in patients with ACD. It helps to distinguish between Iron deficiency anemia and ACDsTfR - ferritin index Calculation of the ratio of sTfR expressed as mgL to ferritin expressed as mcgL, or the ratio of sTfR to the logarithm to the base 10 of the ferritin concentration A sTfRlog ferritin ratio TfR- ferritin index 1 suggests the diagnosis of ACD, while a ratio 2 suggests the presence of IDA. Those with the combination of IDA and ACD will also have a TfR- ferritin index 2.Peripheral blood smearLeukocytosis with a left shift bands and immature forms in the presence of infection Presence of leukemic or malignant cells, or leukopenia lymphocytopenia in cancer or acute or chronic disorders involving the immune systemBone marrow studies Normal or increased amounts of storage iron in bone marrow macrophages Decreased number of sideroblasts 