<prompt> Answer this question truthfullyWhat is Adenomyosis and what is its underlying mechanism pathophysiology?  <response>: <reason> PathologyThe pathogenesis of Adenomyosis is poorly understood. There two theories that explain the possible pathogenesis :The basic Fibroblast Growth Factor bFGF receptorligand system has shown to be upregulated in adenomyosis which explain the abnormal uterine bleeding and menorrhagia . Estrogen and progesterone hormones play a role in the pathogenesis of adenomyosis . Other hormones such as oxytocin , FSH , and prolactin also contribute to the pathogenesis of the disease. On gross pathology, there is a globular enlargement of the myometrium of the uterus showing cysts filled with hemolysed red blood cells and sideroblasts . On microscopic histopathological analysis, there are endometrial glands, and stroma surrounded by hypertrophic smooth muscle bundles haphazardly scattered within the myometrium .ev:youtubenOCtpIwCZ-Y 