<prompt> Answer this question truthfullyWhat causes thyroid nodules?  <response>: <reason> The most important causes of thyroid nodule development include: Causes of benign thyroid nodule: Multinodular sporadic goiter colloid adenoma Hashimotos chronic lymphocytic thyroiditis Cysts colloid, simple, or hemorrhagic Follicular adenomas Macrofollicular adenomas Microfollicular or cellular adenomas Hürthle cell oxyphil cell adenomas Macro- or microfollicular patterns Causes of malignant nodule mutations: Childhood radioiodine exposure Familial historyThe most important genes which can lead to thyroid cancer include: NH ras RET Gsp C-MET α and β subunit TRK EGF EGF-R P53 