<prompt> Answer this question truthfullyWhat are the natural history, complications, and prognosis associated with psoriasis?  <response>: <reason> Individuals with psoriasis may develop the following complications: High-output cardiac failure in erythroderma Psoriatic arthritis Infections Cachexy AmyloidosisAnti-TNF medications given during the management of psoriasis may lead to: Progressive multifocal leukoencephalopathy Optic neuritis Transverse myelitis Multiple sclerosis Infections 