<prompt> Answer this question truthfullyWhat is the medical treatment for chronic myelogenous leukemia?  <response>: <reason> Targeted therapy Targeted therapy with a tyrosine kinase inhibitor may be offered for CML in the blast phase. For those already taking targeted therapy, the dose may be increased. The types of targeted therapy used are: Imatinib DasatinibChemotherapyThe most common drugs used when the leukemia cells appear like AML myeloid blast crisis include: Cytarabine HDAC high-dose cytarabine An anthracycline, such as daunorubicin or doxorubicin Thioguanine Hydroxyurea The most common drugs used when the leukemia cells look like ALL lymphoid blast crisis include the drugs listed above as well as: Vincristine Prednisone Methotrexate 6-mercaptopurine There is increased risk of spread to the central nervous system CNS during the blast phase, so the following chemotherap y drugs may be given into the spinal fluid intrathecal: Cytarabine MethotrexateStem cell transplantAllogeneic stem cell transplantRadiation therapyRadiation therapy may be offered for blast phase CML for: Splenomegaly Bone pain 