<prompt> Answer this question truthfullyWhat is the recommended medical treatment for Shigellosis?  <response>: <reason> As with any infectious diarrhea, the most important initial step in the management of patients with shigellosis is fluid and salt replacement.Oral fluid replacement is sufficient for the majority of patients and can be accomplished by oral glucose or starch-containing electrolyte solutions. Oral rehydration solutions should contain the WHO-recommended electrolyte concentrations Na 90 mM, K 20 mM, Cl 80 mM, HCO3 30 mM, and glucose 111 mM. Oral fluid replacement is superior to IV fluids for patients who can tolerate it.Oral rehydration solutions can be prepared by mixing 3.5 g of NaCl, 2.5 g of NaHCO3 or 2.9 g of Na citrate, 1.5 g of KCl, and 20 g of glucose or glucose polymer e.g., 40 g of sucrose or 4 tablespoons of sugar or 5060 g of cooked cereal flour such as rice, maize, sorghum, millet, wheat, or potato per liter of clean water. IV fluid replacement should be tailored to the individual patients lab findings electrolytes, BUN, creatinine.Antimotility agents such as diphenoxylate or loperamide are not recommended for patients with documented Shigella infections. These agents may prolong the infection and increase the shedding of Shigella organisms. Fever should be treated with antipyretics, particularly among pediatric patients, as shigellosis can be associated with prolonged high grade fevers and febrile seizures.1. Shigellosis 1.1 Adults Preferred regimen 1: Ciprofloxacin 500 mg PO bid for 3 days Alternative regimen 1: Pivmecillinam 100 mg PO qid for 5 days Alternative regimen 2: Azithromycin 1-1.5 g PO qd for 1 to 5 days 1.2 Pediatrics Preferred regimen 1: Ciprofloxacin 15 mgkg PO bid for 3 days Alternative regimen 1: Pivmecillinam 20 mgkg PO qid for 5 days Alternative regimen 2: Ceftriaxone 50-100 mgkg IM qd for 2 to 5 days Alternative regimen 3: Azithromycin 6-20 mgkg PO qd for 1 to 5 days 