<prompt> Answer this question truthfullyWhat is the pathophysiology of primary central nervous system lymphoma?  <response>: <reason> Development of primary central nervous system lymphoma is the result of multiple genetic mutations. Genes involved in the pathogenesis of primary central nervous system lymphoma include: IG BCL6 CD95 CMYC13 PAX5 PIM1 PRDM114 TTF CARD11 MALT1 p50 