<prompt> Answer this question truthfullyWhat is the importance of the COURAGE trial with regards to stable angina and chronic health issues?  <response>: <reason> Patients were required to have both objective evidence of ischemia and significant coronary heart disease in a least one vessel 87 were symptomatic and 58 had Canadian Cardiovascular Society CCS class II or III angina. Approximately, two thirds of the patients had multi-vessel disease.Patients were excluded if they had CCS class IV angina, 50 percent left main disease, a markedly positive treadmill test significant ST segment depressions andor a hypotensive response during stage I of the Bruce protocol, an LVEF less than 30 percent, or coronary lesions deemed unsuitable for PCI. 