<prompt> Answer this question truthfullyWhat are the natural history, complications, and prognosis of gynecomastia?  <response>: <reason> If left untreated patients with gynecomastia may progress to develop psychosocial stresses and rarely breast cancer. The majority of physiological gynecomastia is self-limited. Pathological gynecomastia has an excellent prognosis and responds well to treatment. Pharmacological gynecomastia responds very well to the cessation of the offending agent. 