<prompt> Answer this question truthfullyWhat are the reasons for delayed puberty?  <response>: <reason> Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. There are no life-threatening causes of delayed puberty, however, complications resulting from untreated delayed puberty are common.Delayed puberty may be caused by: Mumps Cryptorchidism Turner syndrome Testicular trauma Testicular torsion Sickle cell disease Thalassemia Kallmann syndrome Isolated hypogonadotropic hypogonadism Hypothalamus-pituitary-gonadal HPG Axis development disorder Obesity and hypogonadotropic hypogonadism Cystic fibrosis Asthma Inflammatory bowel disease Celiac disease Diabetes mellitus Excessive exercise MalnutritionLess common causes of disease name are including: Noonan syndrome and related disorders Fragile X premutation Gonadal dysgenesis Vanishing testes syndrome Coxsackie virus Galactosemia Autoimmune oophiritis Autoimmune orchitis 5-alpha reductase deficiency 17,20- lyase deficiency Congenital lipoid adrenal hyperplasia Androgen insensitivity Sertoli cell only syndrome Del Castillo syndrome Astrocytoma Germinoma Glioma Craniopharyngioma ProlactinomaLangerhans cell histiocytosis Rathke pouch cyst Prader-Willi syndrome Bardet-Biedl syndrome CHARGE syndrome Gaucher disease Post central nervous system infection Septo-optic dysplasia Congenital hypopituitarism Chemotherapy Radiation therapy Juvenile rheumatoid arthritis Anorexia nervosaBulimia Hemosiderosis Chronic renal disease AIDS Hypothyroidism Hyperprolactinemia Growth hormone deficiency Cushing syndromeDelayed puberty is caused by a mutation in the following genes: Kisspeptin system KISS1R and KISS1 Kallmann syndrome 1 KAL1 Fibroblast growth factor receptor 1 FGFR1 Fibroblast growth factor 8 FGF8 Heparan sulfate 6-O-sulphotransferase 1 HS6ST1 Prokineticin 2 PROK2 Prokineticin 2 receptor PROKR2 Tachykinin 3 TAC3 Tachykinin 3 receptor TACR3 Gonadotropin releasing hormone GnRH1 Gonadotropin releasing hormone receptor GnRHR Chromodomain helicase DNA-binding protein 7 CHD7 Nasal embryonic LH-releasing hormone factor NELF Early B-cell factor 2 EBF2 DSS-AHC on the X-chromosome 1 DAX1 Steroidogenic factor 1 SF1 Homeobox gene 1 HESX1 LIM homeobox gene 3 LHX3 PROP paired-like homeobox 1 PROP1 Leptin LEP Leptin receptor LEPR Proprotein convrtase 1 PC1 Makorin RING-finger protein 3 MKRN3 Estrogen receptor α ESR1List the causes of the disease in alphabetical order.5-alpha reductase deficiency 17,20- lyase deficiency AIDS Androgen insensitivity Anorexia nervosa Asthma Astrocytoma Autoimmune oophiritis Autoimmune orchitis Bardet-Biedl syndrome Bulimia Celiac disease CHARGE syndrome Chemotherapy Chromodomain helicase DNA-binding protein 7 CHD7 Chronic renal disease Congenital hypopituitarism Congenital lipoid adrenal hyperplasia Coxsackie virus Craniopharyngioma Cryptorchidism Cushing syndrome Cystic fibrosis Diabetes mellitus DSS-AHC on the X-chromosome 1 DAX1 Early B-cell factor 2 EBF2 Estrogen receptor α ESR1 Excessive exercise Fibroblast growth factor 8 FGF8 Fibroblast growth factor receptor 1 FGFR1 Fragile X premutation Galactosemia Gaucher disease Germinoma Glioma Gonadal dysgenesis Gonadotropin releasing hormone GnRH1 Gonadotropin releasing hormone receptor GnRHR Growth hormone deficiency Hemosiderosis Heparan sulfate 6-O-sulphotransferase 1 HS6ST1 Homeobox gene 1 HESX1 Hyperprolactinemia Hypothalamus-pituitary-gonadal HPG Axis development disorder Hypothyroidism Inflammatory bowel disease Isolated hypogonadotropic hypogonadism Juvenile rheumatoid arthritis Kallmann syndrome Kallmann syndrome 1 KAL1 gene Kisspeptin system KISS1R and KISS1 Langerhans cell histiocytosis Leptin LEP Leptin receptor LEPR LIM homeobox gene 3 LHX3 Makorin RING-finger protein 3 MKRN3 Malnutrition Mumps Nasal embryonic LH-releasing hormone factor NELF Noonan syndrome and related disorders Obesity and hypogonadotropic hypogonadism Post central nervous system infection Prader-Willi syndrome Prokineticin 2 PROK2 Prokineticin 2 receptor PROKR2 Prolactinoma Proprotein convrtase 1 PC1 PROP paired-like homeobox 1 PROP1 Radiation therapy Rathke pouch cyst Septo-optic dysplasia Sertoli cell only syndrome Del Castillo syndrome Sickle cell disease Steroidogenic factor 1 SF1 Tachykinin 3 TAC3 Tachykinin 3 receptor TACR3 Testicular torsion Testicular trauma Thalassemia Turner syndrome Vanishing testes syndrome 