<prompt> Answer this question truthfullyWhat is the biological mechanism behind Peutz-Jeghers syndrome?  <response>: <reason> Polyps of Peutz-Jeghers syndrome are usually non-neoplastic hamartomas. On microscopic histopathological analysis, polyps have the following characteristic findings: Frond-like polyp with all three components of mucosa: Muscosal epithelium melanotic mucosa, goblet cells Lamina propria Muscularis mucosae 