<prompt> Answer this question truthfullyWhat is the natural progression or course of non-small cell lung cancer?  <response>: <reason> Non-small cell lung cancer prognosis and recurrence depends on the origin of primary tumor, histological type, and stage. Non-small cell lung cancer prognosis is generally regarded as poor. Non-small cell lung cancer survival rate ranges from 1 to 52 stage I to stage IV. The recurrence rate of non-small cell lung cancer is 24.The development of complications is associated with worse prognosis. The median survival time of non-small cell lung cancer following a cancer-related complication, such as malignant pleural effusion, is approximately 1 to 3 months. Features associated with worse prognosis, include: Presence of lymphatic invasion Unfavorable genetic expression profile Location of lesion Performance status Presence of satellite lesions Presence of regional or distant metastasesThe table below summarizes the 5-year survival rate according to non-small cell lung cancer stage:Stage 5-year survival rate IA 49 IB 45 IIA 30 IIB 31 IIIA 14 IIIB 5 IV 1 