<prompt> Answer this question truthfullyWhat is the pathophysiology of thrombophlebitis?  <response>: <reason> The pathogenesis of thrombophlebitis is related to 3 important factors: Venous stasisHypercoagulability of bloodTrauma to veinsThese 3 factors known as Virchows triad predispose to thrombus formation within the veins and subsequently to thrombophlebitis.Thrombophlebitis may be associated with the following conditions:Coagulation abnormalities: Factor V Leiden mutation Prothrombin G20210A mutation Protein C deficiency Protein S deficiency Antithrombin III deficiency Thromboangiitis obliterans Buergers Disease Underlying malignancy, especially adenocarcinoma of the pancreas in the case of migratory thrombophlebitis 