<prompt> Answer this question truthfullyCan you provide an overview of nephropathy associated with HIV?  <response>: <reason> The treatment of HIV associated nephropathy HIVAN includes: combined antiretroviral therapy cART, reninangiotensinaldosterone system RAAS blockade, corticosteroids and renal replacement with dialysis. Kidney transplantation is increasing in HIV -positive patients with end-stage renal disease ESRD. Although the rejection rate is high, the graft survival rates are high. Recently reports have shown successful kidney transplantatio n from HIV-positive donors to HIV-positive recipients. HIV -positive patients should be screened for chronic kidney disease CKD. Interventions in HIV-positive patients with renal disease should be done in order to slow the progress and prevent end stage renal disease ESRD and they should be referred to a nephrologist. There is insufficient information about the cost-effectiveness of therapy in HIV associated nephropathy. The World Health Organization WHO data on HIVAIDS for 2018 is 37.9 million people living with HIVAIDS worldwide and 770 000 deaths due to HIV-related illnesses worldwide. Therapies such as molecular targeting require more research. Recently, there have been reports of successful kidney transplantation from HIV-positive donors to HIV -positive recipients. 