<prompt> Answer this question truthfullyWhat is the explanation for Ciliopathy and Ciliopathies?  <response>: <reason> The phenotypic parameters that define a ciliopathy may be used to both recognize the cellular basis of a number of genetic disorders and to facilitate the diagnosis and treatment of some diseases of unknown etiology .Alstrom syndrome Bardet-Biedl syndrome , early embryonic death some cases hydrocephalus some cases Joubert syndrome Meckel-Gruber syndrome nephronophthisis , orofaciodigital syndrome type 1 polycystic kidney disease , polycystic liver disease primary ciliary dyskinesia retinal degeneration some forms Senior-Loken syndrome agenesis of the corpus callosum anencephaly breathing abnomalities cerebellar vermis hypoplasia Dandy-Walker malformation diabetes Ellis-van Creveld syndrome exencephaly eye movement abnormalities liver disease hypoplasia of the corpus callosum hypotonia reproductive sterility Jeune asphyxiating thoracic dystrophy Juvenile myoclonic epilepsy JME Kartagener syndrome Marden-Walker syndrome mental retardation developmental delay or other cognitive defects obesity polydactyly posterior encephalocele respiratory dysfunction recurent respiratory infections renal cystic disease retinitis pigmentosa sensorineural deafness situs inversus Isomerism spina bifida 