<prompt> Answer this question truthfullyCould you provide me with the original text of the question for me to understand the context better?  <response>: <reason> The underlying defect in patients with polycystic ovary syndrome PCOS remains unknown, but a hormonal imbalance between LH FSH and estrogen is mainly responsible for the development of polycystic ovary syndrome. Most studies suggest that more than one factor could play a role in developing Polycystic ovary syndrome PCOS. 