<prompt> Answer this question truthfullyWhat are the factors that lead to hepatocellular adenoma?  <response>: <reason> Estrogen has a central role in the development of hepatocellular adenoma. The causes of hepatocellular adenoma can include the settings involving prolonged andor excessive estrogen exposure, such as: Oral contraceptive medications Pregnancy Glycogen storage disease types I, II and IV Long term use of anabolic androgenic steroids Metabolic syndrome Obesity Clomiphene 