<prompt> Answer this question truthfullyCan you provide a brief summary of what Evans syndrome is?  <response>: <reason> Pharmacologic medical therapies for Evans syndrome include corticosteroids prednisone, intravenous immunoglobulin IVIG, rituximab, anabolic steroids, vincristine, alkylating agents, or cyclosporine.Plasma exchange therapies have also been implicated in its treatment. Refractory disease can be treated by splenectomy and allogeneic hematopoietic stem cell transplant HSCT. Surgery is not the firstline treatment option for patients with Evans syndrome. Splenectomy is usually reserved for patients who are unresponsive to treatment. 