<prompt> Answer this question truthfullyWhat does B cell memory mean?  <response>: <reason> All these events occur in the highly eventful germinal centers of lymphoid follicles, within the lymph nodes.Some of the resulting paratopes and the cells elaborating them have a better affinity for the antigen actually, the epitope and are more likely to proliferate than the others not unlike Charles Darwins concept of natural selection .Moreover, with each such exposure to the antigen the number of different clones responding to the same antigen increase polyclonal response, and a greater number of memory cells persist. Thus, a stronger basically, more number of antibody molecules and more specific antibody-production are the hallmarks of secondary antibody response.The facts that all the cells of a single clone elaborate one and only one paratope, and that the memory cells survive for long periods, are what impart a memory to the immune response.This is the principle behind vaccination and administration of booster doses. 