<prompt> Answer this question truthfullyCan you provide an overview of milk-alkali syndrome?  <response>: <reason> The exact incidence and prevalence of milk-alkali syndrome is not known. With the introduction of histamine antagonists and decrease in antacid consumption since the 1970s, the incidence of milk-alkali syndrome has decreased significantly. However, since the 1990s, there has been an increase in milk-alkali syndrome due to increase in calcium and vitamin D consumption in postmenopausal women for osteoporosis prevention. Milk-alkali syndrome is the third most common cause of hypercalcemia in hospitalized patients after primary hyperparathyroidism and malignancies. 