<prompt> Answer this question truthfullyWhat is the historical background of Boerhaave syndrome?  <response>: <reason> Boerhaave syndrome was first described by the physician Herman Boerhaave, Professor of Medicine at Leiden University, in a publication entitled History of a Grievous Disease Not Previously Described. Dr. Herman Boerhaave 1668-1738 described esophageal rupture and the subsequent mediastinal sepsis based upon his careful clinical and autopsy findings. Hundreds of references have since been written about Boerhaaves syndrome. 