<prompt> Answer this question truthfullyCould you please explain what Gilberts syndrome is?  <response>: <reason> Gilberts syndrome is caused by approximately 30-50 reduced glucuronidation activity of the enzyme Uridine-diphosphate-glucuronosyltransferase isoform 1A1 UGT1A1. The gene which encodes UGT1A1 normally has a promoter region TATA box containing the allele ATA 6TAA. Gilberts syndrome is associated with homozygous ATA 7TAA alleles. The allele polymorphism is referred to as UGT1A128. 