<prompt> Answer this question truthfullyWhat are the natural history, complications, and prognosis associated with Rhabdomyosarcoma?  <response>: <reason> Rhabdomyosarcoma prognosis are considered as a favorable one in presence of following criteria: No distant metastases at diagnosis Primary tumors sites: Orbit tumors Nonparameningeal head and neck tumors Genitourinary tumors non- bladder or prostate tumors Complete surgical removal of the localized tumor at the time of diagnosis Embyonal rhabdomyosarcoma or botryoid on histology Tumor size 5 cm Patients age between 1 to 10 years old Adults and adolescents have worse outcome rather than children. The overall 5-year survival rate is 27 in adults while it is 61 in children. This difference is regarding to unfavorable tumor sites, metastatic recurrence, lymph nodes involvement, and pleomorphic and NOS not otherwise specified rhabdomyosarcoma. The survival rate and event-free survival rate of nonmetastatic tumors are as following: Tumors location Overall survival rate Event-free survival rate Head and neck tumors 64 35 Orbit 85 53 Paramenigeal tumors In age 3 years: 59 In age 3 years: 65 In age 3 years: 33 In age 3 year:62 Genitourinary tumors non- bladder and prostate 94 82 Genitourinary tumors bladder and prostate 80 64 Extremities 46 35 Other sites 63 54 