<prompt> Answer this question truthfullyWhat is the epidemiology and demographic profile of individuals with Bicuspid aortic stenosis?  <response>: <reason> Bicuspid aortic valve has been found to be an inheritable condition, with a demonstrated association with Notch 1. Familial clustering as well as isolated valve defects have been documented. The incidence of bicuspid aortic valve can be as high as 10 to 20 in families affected with the valve problem . Other congential heart defects are associated with bicuspid aortic valve at various frequencies. 