<prompt> Answer this question truthfullyWhat is the natural course or progression of mitral regurgitation?  <response>: <reason> Mild MR is associated with few if any complications. However, when severe, MR may lead to development of in alphabetical order:Atrial fibrillation Cardiogenic Shock Endocarditis Pulmonary edema Pulmonary hypertension Right heart failure Thromboembolism - Stroke 