<prompt> Answer this question truthfullyWhat is the underlying process of lymphadenopathy?  <response>: <reason> On microscopic histopathological analysis, characteristic findings of lymphadenopathy will depend on the etiology.Common findings, include: Non-specific reactive follicular hyperplasia NSRFHLarge spaced cortical follicles Tingible body macrophages, normal darklight GC patternLymph node metastasisForeign cell population usually in subcapsular sinuses -nuclear atypia - malignant architectureToxoplasmosisLarge follicles Epithelioid cells perifollicular intrafollicular Reactive GCs Monocytoid cell clustersCat-scratch diseasePMNs in necrotic area Stellate or serpentine shaped micro-abscesses Presence of granulomasDermatopathic lymphadenopathyMelanin -laden histiocytes HistiocytosisSystemic lupus erythematosus lymphadenopathyBlue hematoxylin bodies Necrosis No PMNsHistology can provide more information regarding the cause of lymphadenopathy when etiology is not clear during initial history taking, physical examination, and laboratory evaluation.Common causes of lymphadenopathy with their associated histological findings include:Bacterial lymphadenitis: Neutrophil -rich infiltrate can be found within the sinus and medullary cords. Follicular hyperplasia can be seen as well. Viral lymphadenopathy: Macrophage infiltration and lymphoid hyperplasia. Necrosis can be seen in those who are immunocompromised. Sarcoidosis: non-caseating granulomas that replace the normal architecture of the lymph node Non-Hodgkin lymphoma: There is partial or widespread loss of the lymph node by a single cell lineage. Lymphoid cells can either proliferate in a disorderly manner or as those that mimic follicular center structures. Hodgkin lymphoma: Can be classified by the histological appearance from most common to least: Nodular-sclerosing Mixed cellularity Lymphocyte -rich Lymphocyte -depleted 