<prompt> Answer this question truthfullyWhat is tuberculosis in children? The original sentence is already in proper English.  <response>: <reason> Empirica l treatment should be started and the regimen should be modified according to the DST Drug susceptibility testing results. Drug dosing should be calculated according to the childs weight, regardless the age. Pediatricians should closely monitor adverse drug reactions and manage them appropriately. For drug-resistant tuberculosis, hospitalization is often required for the administration of IV medications. The treatment duration for drug-susceptible TB is 6 months. The treatment duration for drug-resistant tuberculosis will depend on the culture results. The duration of therapy should be at least 18 months after the culture is negative. Weight gain and resolution of symptoms are good markers for a good response to treatment. Click on the following categories to expand treatment regimens.Tuberculosis in Children Drug Susceptible TB MDR-TB XDR-TB Drug Susceptible TB Regimen Initial phase Administer each drug daily for 8 weeks Isoniazid 10 mgkg PO Max: 300 mgday PLUS Rifampicin 15 mgkg PO Max: 600 mgday PLUS Pyrazinamide 35 mgkg PO Max: 2 gday PLUS Ethambutol 20 mgkg PO Max: 1.6 gday Continuation phase Administer each drug daily for 18 weeks Isoniazid 10 mgkg PO Max: 300 mgday PLUS Rifampicin 15 mgkg PO Max: 600 mgday Table adapted from WHO 2013 Treatment of Tuberculosis: Guidelines 4th ed. MDR-TB Regimen Standard Regimen Group 1: First-line oral drugs Pyrazinamide 20-30 mgkg Max: 600 mg OR Ethambutol 15-20 mgkg OR Rifabutin 5 mgkg PLUS Group 2: Injectable drugs Capreomycin 15-30 mgkg Max: 1000 mg OR Kanamycin 15-30 mgkg Max: 1000 mg OR Amikacin 15-22.5 mgkg Max: 1000 mg OR Streptomycin 12-18 mgkg PLUS Group 3: Fluoroquinolones Levofloxacin 7.5-10 mgkg OR Moxifloxacin 7.5-10 mgkg OR Ofloxacin 15-20 mgkg divided q12h Max:800 mg PLUS Group 4:Oral bacteriostatic second-line drugs Ethionamide 15-20 mgkg divided q12h Max: 1000 mg OR Protionamide 15-20 mgkg divided q12h Max: 1000 mg OR Cycloserine 10-20 mgkg Max: 1000 mg OR Terizidone 10-20 mgkg Max: 1000 mg OR Para-aminosalicylic acid 150 mgkg divided q8-12hMax: 12 000 mg Table adapted from WHO 2013 Treatment of tuberculosis: guidelines 4th ed. and Guidance for national tuberculosis programmes on the management of tuberculosis in children XDR-TB Regimen Standard Regimen Group 1: First-line oral drugs Pyrazinamide 20-30 mgkg Max: 600 mg OR Ethambutol 15 mgkg OR Rifabutin 5 mgkg PLUS Group 4:Oral bacteriostatic second-line drugs Ethionamide 15-20 mgkg Max: 1000 mg OR Protionamide 15-20 mgkg Max: 1000 mg OR Cycloserine 10-20 mgkg Max: 1000 mg OR Terizidone 10-20 mgkg Max: 1000 mg OR Para-aminosalicylic acid 150 mgkgd divided q8-12h PLUS Group 5 Use at least 2 of the following: Clofazimine 50 mgd AND 300 mg once a month OR Amoxicillin clavulanate OR Linezolid 300-600 mg OR Imipenem 500mg q6h OR Clarithromycin 500-1000 mg q12h OR Thioacetazone 2.5 mgkg OR Isoniazid high-dose 1620 mgkg Table adapted from WHO 2013 Treatment of tuberculosis: guidelines 4th ed. and WHO Guidance for national tuberculosis programmes on the management of tuberculosis in children 