<prompt> Answer this question truthfullyCan you provide an overview of Hepatitis B?  <response>: <reason> High-risk groups should be tested for HBV infection. These include immigrantsrefugees from areas of intermediate or high endemicity, patients with chronically elevated aminotransferases, immunocompromised individuals, and people with a history of injection drug use IDU. Additionally, screening for hepatocellular carcinoma should extend to any HBV carrier over 40 years of age with persistent or intermittent ALT elevation andor high HBV DNA levels 2,000 IUmL. 