<prompt> Answer this question truthfullyWhat medical therapy is used for stroke related to atrial septal defect?  <response>: <reason> Aspirin has been found to decrease the incidence of recurrent stroke and transient ischemic attacks in patients with atrial septal defect and patent foramen ovale . The American Heart Association guidelines support the utilization of sustained warfarin therapy in high-risk atrial septal defect patients. 