<prompt> Answer this question truthfullyWhat are the natural history, complications, and prognosis associated with ulcerative colitis?  <response>: <reason> The course of the disease generally varies. Ulcerative colitis may be inactive and then get worse over a period of years. Sometimes ulcerative colitis can progress quickly. A permanent and complete cure is unusual. 67 patients relapse within 10 years of the initial diagnosis. 