<prompt> Answer this question truthfullyWhat are the historical background and symptoms of Whipples disease?  <response>: <reason> Patients with Whipples disease have various presentations. Most common symptoms of the classic Whipples disease include joint pain, weight loss, diarrhea, and abdominal pain. Other organ systems can be involved in Whipples disease including central nervous system, cardiac system, renal system, skeletal, muscles and pulmonary system. 