<prompt> Answer this question truthfullyWhat is the cause of glycogen storage disease type II?  <response>: <reason> Glycogen storage disease type 2 is an autosomal recessive disorder. Glycogen storage disease type 2 is caused by the deficiency of the lysosomal acid alpha-1,4-glucosidase enzyme. GAA gene responsible for the lysosomal acid alpha-1,4-glucosidase enzyme deficiency is located on chromosome 17q25. 