<prompt> Answer this question truthfullyWhat medical treatment is available for blastomycosis?  <response>: <reason> BlastomycosisMild to moderate pulmonary blastomycosis Preferred regimen: Itraconazole 200 mg PO q12-24h for 612 months Note:Initially oral Itraconazole, 200 mg for 3 days and then q12-24h for 612 months, is recommendedModerately severe to severe pulmonary blastomycosis Preferred regimen1: Lipid amphotericin B Lipid AmB 35 mgkg IV q 24h for 12 weeks AND Itraconazole 200 mg PO q 12h for 612 months Preferred regimen2: Amphotericin B deoxycholate 0.71 mgkg IV q 24h for 12 weeks AND Itraconazole 200 mg PO q 12h for 612 months Note: Oral Itraconazole, 200 mg q8h for 3 days and then 200 mg q12h for 612 months, is recommendedMild to moderate disseminated blastomycosis Preferred regimen: Itraconazole 200 mg PO q12-24h for 612 months Note1: Treat osteoarticular disease for 12 months Note2: Oral Itraconazole, 200 mg q8h for 3 days and then 200 mg q12h for a total of 612 months, is recommendedModerately severe to severe disseminated blastomycosis Preferred regimen1: Lipid amphotericin B Lipid AmB 35 mgkg IV q24h for 12 weeks AND Itraconazole 200 mg PO q12h for 612 months Preferred regimen2: Amphotericin B deoxycholate 0.71 mgkg IV q24h for 12 weeks AND Itraconazole 200 mg PO q12h for 612 months Note: oral Itraconazole, 200 mg q8h for 3 days and then 200 mg q12h, for a total of 612 months, is recommendedCNS disease Preferred regimen: Lipid amphotericin B Lipid AmB IV 5 mgkg q24h for 46 weeks AND an oral azole for at least 1 year Note1: Step-down therapy can be with Fluconazole, 800 mg per day OR Itraconazole, 200 mg q8-12h per day OR voriconazole, 200400 mg q12h Note2: Longer treatment may be required for immunosuppressed patients.Immunosuppressed patients Preferred regimen1: Lipid amphotericin B Lipid AmB, 35 mgkg IV q24h for 12 weeks, AND Itraconazole, 200 mg PO q12h for 12 months Preferred regimen2: Amphotericin B deoxycholate, 0.71 mgkg IV q24h, for 12 weeks, AND Itraconazole, 200 mg POq12h for 12 months Note1: Oral Itraconazole, 200 mg q8h for 3 days and then 200 mg q12h, for a total of 12 months, is recommended Note2: Life-long suppressive treatment may be required if immunosuppression cannot be reversed.Pregnant women Preferred regimen: Lipid amphotericin B Lipid AmB 35 mgkg IV q24h Note1: Azoles should be avoided because of possible teratogenicity Note2: If the newborn shows evidence of infection, treatment is recommended with Amphotericin B deoxycholate, 1.0 mgkg IV q24hChildren with mild to moderate disease Preferred regimen: Itraconazole 10 mgkg PO q24h for 612 months Note: Maximum dose 400 mg q24hChildren with moderately severe to severe disease Preferred regimen1: Amphotericin B deoxycholate 0.71 mgkg IV q24h for 12 weeks AND Itraconazole 10 mgkg PO q24h to a maximum of 400 mg q24h for 612 months Preferred regimen2: Lipid amphotericin B Lipid AmB 35 mgkg IV q24h for 12 weeks AND Itraconazole 10 mgkg PO q24h to a maximum of 400 mg q24h for 612 months Note: Children tolerate Amphotericin B deoxycholate better than adults do. 