<prompt> Answer this question truthfullyCan you provide an explanation of Barretts esophagus?  <response>: <reason> Barretts esophagus is a major risk factor for development of esophageal adenocarcinoma. After diagnosis, regular surveillance is needed based on the grade of dysplasia. Screening for barretts esophagus is strongly recommended with multiple risk factors for esophageal adenocarcinoma include: Age 50 years old, male, white, chronic GERD, hiatal hernia, elevated BMI body mass index, and intra-abdominal distribution of body fat. Screening is weakly recommended in general population with GERD and no risk factors. 