 I-Lorcaserin hydrochloride hemihydrate powder i-856681-05-5 ividiyoI-Lorcaserin hydrochloride hemihydrate powder 856681-05-5 ImininingwaneIgama Product I-Lorcaserin hydrochloride hemihydrate powderIgama leKhemikhali I-Lorcaserin hydrochloride, R -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate; R -8-chloro-2,3,4,5-tetrahydro-1-methyl-1h-3-benzazepine i-hydrochloride hemihydrateCAS Inombolo 856681-05-5InChIKey I-WRZCAWKMTLRWPR-VSODYHHCSA-NI-molecular Fi-ormula C22H32Cl4N2OI-molecular Weziyisishiyagalombili 482.31IMisa ye-Monoisotopic 480.1268745I-Half Half-Life I-Lorcaserin inempilo yengxenye ye-plasma ye amahora angu-11solubility Umswakama wamanzi 0.0709 mg mLStorage Tukushisa Ayikho idatha etholakalayoAukuphikisana I-Lorcaserin hydrochloride i-hemihydrate powder esetshenziswa njengesidakamizwa sokulwa nokukhuluphala ngokweqile. Inendima njengengcindezi yondla futhi i-agonist ye-serotonergic.I-Lorcaserin hydrochloride hemihydrate powder 856681-05-5 IncazeloI-Lorcaserin hydrochloride i-hemihydrate powder iyi-hydrate eyinhlobo ye-hemihydrate ye-lorcaserin hydrochloride. Isetshenziswa njengesidakamizwa sokulwa nokukhuluphala ngokweqile. Inendima njengengcindezi yondla futhi i-agonist ye-serotonergic. Iqukethe i-lorcaserin hydrochloride.I-Lorcaserin hydrochloride hemihydrate powder isetshenziswa ukuphatha ukukhuluphala okuhambisana ne-cholesterol ephezulu, ukucindezelwa kwegazi, noma ukuthayipha i-2 sikashukela.I-FDA igunyaze i-Raw Lorcaserin hydrochloride hemihydrate powder kubantu abakhuluphele abanezibalo zomzimba, noma i-BMI, ye-30 noma ngaphezulu noma abakhuluphele abane-BMI ye-27 noma ngaphezulu futhi banenani okungenani isisindo esisodwa- isimo sezempilo esihlobene nohlobo lwe-2 yesifo sikashukela, umfutho wegazi ophakeme noma i-cholesterol ephakeme.I-Lorcaserin hydrochloride i-hemihydrate powder isebenza ngokulawula ukudla - ikakhulukazi ngokusungula izinkinga zokuphefumula ze-serotonin, i-neurotransmitter edala imizwa yokukhathazeka nokwaneliseka. I-Serotonin nayo ihilelekile ekudumeni; izidakamizwa eziningi ezicindezelayo zisebenza ngokuvimbela i-reuptake ye-serotonin nokugcina ubuchopho bamukelekile emakhemikhali. Abacwaningi e-Arena bathi izidakamizwa zabo zenzelwe ukufuna kuphela izamukeli ze-serotonin ezithinta ukudla.I-Lorcaserin hydrochloride i-hemihydrate powder i-856681-05-5 Inqubo yesenzoI-Lorcaserin ikholelwa ukuthi iyanciphisa ukusetshenziswa kokudla futhi ikhuthaze ukungahambi kahle ngokukhetha ngokuphumelelayo ama-receptor we-5-HT2C kuma-neuron an-opiomelanocortin anorexigen ase-hypothalamus. Indlela eqondile yokusebenza ayaziwa.I-Lorcaserin kumthamo wansuku zonke onconywayo usebenzelana ngokukhetha nama-receptor we-5-HT2C uma kuqhathaniswa namamukeli we-5-HT2A kanye ne-5-HT2B bona ithebula le-5, amanye ama-subtypes we-5-HT receptor, kanye ne-5-HT. .Isicelo we-Lorcaserin hydrochloride hemihydrate powder 856681-05-5Ukucindezela ukudla: I-Agent esetshenziselwa ukunciphisa ukudla.i-serotonergic agonist: I-agent ene-affinity ye-serotonin receptors futhi iyakwazi ukulinganisa imiphumela ye-serotonin ngokugqugquzela umsebenzi we-physiologic ema-receipt cell. Ama-agonists aseSerotonin asetshenziswa njengama-anti-depressants, i-anxiolytics, kanye nokwelashwa kwezidakamizwa ze-migraine.Kunconywe i-Lorcaserin hydrochloride hemihydrate powder i-856681-05-5Njengoba ulwazi olufanele mayelana nokusetshenziswa kukaLorcaserin hydrochloride hemihydrate alutholakalanga, ulwazi olulandelayo lubhekisela kuphela:Umthamo ophakanyisiwe we-lorcaserin ngu-10 mg olawulwa ngomlomo kabili ngosuku. I-Lorcaserin ingathathwa ngaphandle kokudla. I-Lorcaserin kufanele ishiywe ezigulini ezingaphumeleli ukufezekisa okungenani ukulahlekelwa kwe-5 ngesonto 12 kusukela lezi ziguli zingenakuthola ukulahlekelwa kwesisindo esinomsoco ngokuphathwa okuqhubekayo.Izinzuzo I-Lorcaserin hydrochloride i-hemihydrate powder i-856681-05-5I-Lorcaserin hydrochloride i-hemihydrate powder iyinhlangano ye-5-HT2C ye-receptor agonist ecatshangelwa ukunciphisa ukudla okudliwayo ngokusebenzisa uhlelo lwePOMC oluphakathi. Izinzuzo ze-Lorcaserin HCL:I-Lorcaserin hydrochloride i-hemihydrate powder isetshenziselwa kanye nokudla nokuzivocavoca ukwelapha ukukhuluphala.I-Lorcaserin hydrochloride i-hemihydrate powder ngezinye izikhathi isetshenziselwa ukuphatha ukukhuluphala okungase kuhlobene nesifo sikashukela, i-cholesterol ephakeme noma ukucindezelwa kwegazi eliphezulu.I-Lorcaserin hydrochloride i-hemihydrate powder ngeke iphathe noma yiziphi izimo zempilo ezingaphansi ezifana nesifo senhliziyo, isifo sikashukela, umfutho wegazi ophezulu.Okuqhamuka uma udla imishanguzo we-Lorcaserin hydrochloride hemihydrate powder 856681-05-5I-Lorcaserin hydrochloride i-hemihydrate powder isetshenziselwa ukwelashwa kokuphathwa kwesisindo esingapheli kubantu abadala abane-index mass body BMI ye-30 noma enkulu obese kakhulu njengokungeza ekudleni okuncishisiwe-khalori nokuzivocavoca. Iphinde ivunyelwe ukusetshenziswa ngabantu abadala abane-BMI ye-27 noma enkulu ngokweqile kakhulu futhi okungenani abanesimo esisodwa esisondelene nesisindo esinjengesiphakamiso esiphakeme segazi i-hypertension, noma i-cholesterol ephakeme i-dyslipidemia. Nokho, kungase kube neminye imiphumela emibi. Njengezansi:TImiphumela emibi kakhulu:Ezinye imiphumela ezingavamile kodwa ezibi kakhulu ezihambisana ne-lorcaserin zihlanganisa: 