<qa>  What is the name of the type of tumors that are symptomatic?2. Patients with MCL must be symptomatic and need immediate therapy. Symptoms and nature of MCL include any of the following: a blastoid variant; b pleomorphic variant; c B symptoms, d MIPI 3, e Ki 67 30, f bulky tumors 7 cm or in case of 2 tumors, each 5 cm in diameter, g disease threatening organ function, h elevated LDH, i PB WBC 50,000, j pancytopenia due to bone marrow MCL, k patients choice due to anxiety; l pain due to lymphoma; m somatic mutations in the TP53, c-MYC or NOTCH genes; n size of spleen 20 cm 