<qa>  How many subjects per treatment will be enrolled?A total of 90 subjects 15 per treatment will be enrolled to ensure 12 subjects per treatment at the Day 14 evaluation, accounting for a 20 drop-out rate. A sample size of 12 subjects per treatment is required to detect a treatment difference of 28 in percent change of eNO at Day 14, assuming a pooled standard deviation of 20 with a power of 90. These estimates are based on examination of eNO levels in asthmatic vs healthy subjects in an article written by S.A. Kharitonov et. al, 2003. 