<qa>  What is the history of drinking alcohol for male subjects?- Subject has a history of drinking 21 units of alcohol per week for male subjects or 14 units of alcohol for female subjects 1 unit 10 g pure alcohol 250 mL of beer 5 or 35 mL of spirits 35 or 100 mL of wine 12 within 3 months prior to admission to the clinical unit on day -1. 