<qa>  What is the relationship between patients treated with iovera and patient reported pain and functionThis study is designed to investigate whether iovera treatment prior to Total Knee Arthroplasty TKA decreases cumulative patient opioid use over the course of 6 weeks following TKA while maintaining similar levels of pain relief. The study will also investigate whether there is a relationship between patients treated with iovera and patient reported pain and function as measured by KOOS JR., NRS for Pain; use of hospital services post-TKA and improved physical rehabilitation as measured by range of motion. 