<qa>  What is the goal of this study?The goal of this study is to evaluate safety and efficacy of bone marrow BM as site for pancreatic islet transplantationin humans. Our hypothesis is that BM represents a better site than liver currently the location of choice for this procedure thanks to its potential capacity to favor islet engraftment. To address our hypothesis we propose herein a randomized phase II trial to compare BM and liver as sites for islet transplantation in T1D patients. 