<qa>  What is the frequency of significant, permanent neurologic damage?Resuscitation can only be considered successful if the survivor has no disabling cognitive function. The American Heart AssociationInternational Liaison Committee on Resuscitation guidelines state that with a duration of cardiac arrest of 8 to 10 minutes, the frequency of significant, permanent neurologic damage becomes unacceptably high. Newer treatment modalities are needed to improve patient outcomes. 