<qa>  How many patients will enroll in the study?The study will enroll approximately 300 patients. Participants with body weight 20 kg will receive the recommended dose of leuprorelin 3.75 mg subcutaneous injection every 4 weeks for 96 weeks. Participants with body weight 20 kg will receive recommended dose of 1.88 mg subcutaneous injection every 4 weeks for 96 weeks. 