<qa>  What is the name of the abnormality at Screening?4. Myocardial infarction within 6 months prior to enrollment or has New York Hospital Association NYHA Class III or IV heart failure, uncontrolled angina, severe uncontrolled ventricular arrhythmias or electrocardiographic evidence of acute ischemia or active conduction system abnormalities. Prior to study entry , any ECG abnormality at Screening has to be documented by the investigatorco-investigator as not medically relevant. 