<qa>  What is the only way to compromise use of epinephrine?15. Patients who require anticoagulation or systemic steroids at doses 10 mg daily of prednisone or equivalent or any immunosuppressive drugs. Beta-blocker therapy, while not exclusionary, is discouraged and alternatives should be sought if possible. The beta-blocker might compromise use of epinephrine for the rare possibility of anaphylaxis. 