<qa>  What is the condition associated with frequent diarrhea associated with?- Patients must not have other significant medical, surgical, or psychiatric conditions or require any medication or treatment that in the opinion of the investigator may interfere with compliance, make the administration of the study drugs hazardous or obscure the interpretation of adverse events AEs, such as a condition associated with frequent diarrhea; patients must not have an active infection requiring current treatment with parenteral antibiotics 