<qa>  How many subjects per study group will be enrolled to ensure a total of 24 subjectsA total of 30 subjects will be evaluated 15 in each study group based on a power of 0.8 and a significance level of 0.05. Data obtained from medication usage evaluations at the UCH were used to estimate the mean and standard deviations for the change in cumulative fentanyl equivalent doses for the four hour period before vs. after dressing changes. Using standard deviations of 130mcg, 12 subjects are required in each study group to show a desired difference of 150mcg between groups when comparing the magnitude of change in the fentanyl dose before vs. after the procedure. While all dressing changes will be evaluated, it was assumed for this analysis that only one dressing change per subject will occur. An additional three subjects per study group will be enrolled to ensure a total of 24 subjects assuming an upper limit of 20 for a possible drop-out rate. Thirty subjects provides power of 0.8 at a significance level of 0.05 to detect a 50 decline in patients reporting moderate pain by VAS or BSPAS or anxiety by SASRS assuming the baseline rates exceed 80. 