<qa>  What is the name of the program that will be used to determine the psychobehavioralTo determine the psychobehavioral and neurohormonal mechanisms of effective treatment, the investigator will conduct a randomized, double-blind, placebo-controlled trial in patients with major depression, who will receive either: i computer-based cognitive behavioral therapy CBT program entitled Beating the Blues placebo, or ii computer-based cognitive behavioral therapy CBT program entitled Beating the Blues the SSRI antidepressant escitalopram. The investigator will assess a glycemic control levels of glycated hemoglobin HbA1c, in relation to b adherence keeping scheduled return appointments, diet, exercise, and glucose monitoring, c depressive symptoms neurocognitive and neurobehavioral symptoms determined by self- and observer-rated scales, and d the four pathways of neurometabolic function. 