<qa>  What is the mRNA expression of enzymes in tumors of the patients entered on thisIII. To evaluate the mRNA expression of enzymes in tumors of the patients entered on this study which may be important to the cytotoxicity of oxaliplatin ERCC1, mismatch repair, ribonucleotide reductase, bcl-2, bax, p53. An attempt will be made to obtain tumor biopsies from all patients. 