<qa>  What is the name of the drug known to have major organ toxicity?- Have received the following systemic treatments within the designated period before study treatment initiation: Interferon 6 weeks, Immunomodulators or immunosuppressive therapies 10 weeks, Cytotoxic drugs 6 months, Investigational drugs 8 weeks, Drugs known to have major organ toxicity 8 weeks, Corticosteroids oral or injectable 6 weeks, Inhaled corticosteroids 1200 ngday for beclomethasone, or 600 ngday for fluticasone4 weeks 