<qa>  How many new onset schizophrenics may be collected each year?According to empirical experience, around 150 new onset schizophrenics may be collected each year from our three collaborative sites. For chronic schizophrenics, clinicians must be aware that the eligible patients are those who can be suitably grouped in statistics e.g., poor responder to typical psychotics. Eligible subjects will be invited to participate in this study, after the signing of written informed consent. 