<qa>  What is the dose of ERC-CBZ initiated at 200mg twice daily?Patients with Bipolar I or II Disorder with a Major Depressive Episode who sign informed consent and meet eligibility criteria will begin treatment with extended release carbamazepine ERC-CBZ . The dose of ERC-CBZ will be initiated at 200mg twice daily and increased as tolerated by 200mgday every 3 days up to 1200mgday by week 2 target dose. Then the dose may be increased at the investigators discretion, up to1600mgday as tolerated by week 8, if needed for a greater therapeutic response. Efficacy will be assessed biweekly with the Montgomery-Asberg Depression Rating Scale MADRS and Clinical Global Impression-Bipolar CGI-BP. Safety is assessed biweekly with adverse events self-reports and laboratory evaluations. . 