<qa>  What is the name of the symptom of a VELCADE?Exclusion Criteria:1Prior exposure to VELCADE.2Has known hypersensitivity or intolerance to omeprazole, boron, mannitol or heparin. 3Medical history of of liver or renal insufficiency; significant cardiac, vascular, pulmonary, GI, endocrine, neurologic, rheumatologic, pyschiatric or metabolic disturbances. 4Uncontrolled diabetes. 5history of hypotension or decreased blood pressure;6Uncontrolled or severe cardiovascular disease incl. myocardial infarction within 6 mos of enrollment; 7History of alcoholdrug abuse. 8Presence of HIV antibodies, hepatitis C antibodies or hepatitis B. 9active systemic infection requiring treatment; 10Pregnant or breastfeeding 11neuropathy Gr.1; 12transfusion dependence; 12pre-planned surgeries or procedures that would interfere with conduct of study 