<qa>  What is the maximum limit of normal for the institution 24?13. Previous treatment with a selective FGF19-FGFR4 targeted therapy andor selective pan-FGFR inhibitor 14. Use of any vaccines against infectious diseases eg, influenza, varicella within 4 weeks 28 days of initiation of study therapy 15. Presence of gastric or esophageal varices requiring active treatment 16. A clinically significant ECG abnormality, including a marked baseline prolonged QTc interval eg, a repeated demonstration of a QTc interval 500 ms 17. Significant cardiovascular impairment or any other major illness, medical condition 19. Males who have not had a successful vasectomy confirmed azoospermia or they and their female partners do not meet the criteria 20. Hypersensitivity to the study drug or to any of the excipients 21. Intolerance or hypersensitivity to both CT and MRI contrast material that would preclude the ability to acquire the triphasic liver imaging required by the protocol 22. Participants with inorganic phosphorus upper limit of normal for the institution 23. Participants with total or ionized serum calcium upper limit of normal for the institution 24. Participants with endocrine changes that may result in increases in calcium or phosphate, including but not limited to hyperparathyroidism and tumoral calcinosis 25. Participants with past medical history andor current evidence of tumoral calcinosis or tissue calcification 26. Participants who take calcium, vitamin D or systemic corticosteroids 