<qa>  What is the dose of ACTH and OGTT?During the study NNT_p.G200S homozygous patients no.-3 will be hospitalised for ACTH and OGTT tests and start ascorbic acid treatment at a doses of 75-80 of the upper limit of allowance according to IOM. ACTH and OGTT will be repeated 6 months later to assess improvement in glucocorticoids production and insulin resistance. 