<qa>  What is the 0.001 alpha level for the composite of time to all-causeInterim Safety Analysis: A maximum of 3 months following inclusion of the first 1000 patients an independent endpoint committee IEC will monitor study endpoints. Variables to be assessed are all-cause death, a new myocardial infarction and stent thrombosis. Premature termination of the study will be mandated in the event that one of the treatment strategies shows statistically significance at the 0.001 alpha level for the composite of time to all-cause death, a new myocardial infarction or stent thrombosis. 