<qa>  What is measurable disease defined as?- Patients must have measurable disease, defined as lesions that can be accurately measured in at least one dimension longest diameter to be recorded as 20 mm with conventional techniques or as 10 mm with spiral CT scan, and which has clearly progressed during the observation interval prior to participation in this study; pleural effusions and ascites will not be considered measurable, but may be present in addition to the measurable lesions 