<qa>  What is the effect of temozolomide treatment?This pilot, partially randomized clinical trial studies how well glycosylated recombinant human interleukin-7 works in increasing low cluster of differentiation CD4 counts after concurrent radiation and temozolomide treatment in patients with gliomas that tend to grow rapidly and spread high-grade. Treatment with radiation and chemotherapy, such as temozolomide, may cause an abnormal decrease in CD4 cells, which are an important part of the immune system. Glycosylated recombinant human interleukin-7 may increase CD4 cell counts and improve survival. 