<qa>  What is CYP1A2, CYP2C8, CYP2C- While not an exclusion criterion, unless clinically indicated, patients should avoid taking other additional non-study medications that may interfere with the study medications; in particular, patients should avoid medications that are known to strong inhibitor or inducers of hepatic microsomal isoenzymes CYP1A2, CYP2C8, CYP2C9, CYP2C19, CYP3A45, UGT1A1, UGT1A3 and transporters BCRP and P-gp 