<qa>  What is the random allocation sequence managed by?Experimental and control interventions Eligible subjects will be randomly and blindly allocated to one of the three groups, to be decided by a computer-generated randomised table. Restricted randomisation by blocking will be used to ensure approximately similar sample sizes for each group at any time during the trial according to equal proportion rule 1:1:1. The random allocation sequence will be managed by a specified research assistant RA who is not involved in this trial and is concealed to the assessors. 