<qa>  What is the duration of subject participation from signing the informed consent form?The duration of subject participation from signing the informed consent form will be up to 14 months includes screening period 1 Day, study IV drug administration approximately 2-14 Days, Standard of Care Oral Drug Administration 4-5 weeks the total maximum treatment period is typically 6 weeks, and a follow-up visit 12 months after the last dose of study drug. Baseline assessments for study eligibility will occur within 24 hours before the first dose of study drug. A minimum of 2 days 48 hours of study drug administration is required. 