<qa>  What is the best way that shigyakusan is prescribed to placebo for clear endThe author thinks that double blind study is the best way that shigyakusan is prescribed to placebo for clear endpoint discovered though it is very difficult to the psychiatric disorder as IBS. However, this time the author assessed the self-declaration of the symptoms change. The change of the symptom was showed with an arrow by self-declaration. An entry format was adopted by showing Table 1 to the patients. For example, 31 shows the change of symptoms from 3 Significantly bad to 1 Almost no symptoms in Table 1. The author used shigyakusan regardless of diarrhea or constipation. 