<qa>  What is the name of the study that is a collaboration between Wright State University and the SouthwestThe study consists of four specific aims: 1 Collect 25-year follow-up data from approximately 500 of the original participants, and new data from approximately 500 of their relatives not examined in the original study. The cardiovascular disease risk factor phenotypes to be collected include hemodynamic measures, carotid intima-media thickness, and measures of cardiopulmonary function. 2 Obtain DNA samples from these 1,000 individuals and use modern high-throughput molecular genotyping methods to create a 10 cM genetic marker map. 3 Quantify and characterize the nature of genetic influences on CVD risk factors using quantitative genetic methods suited for cross-sectional and serial follow-up data from relatives in large extended families. 4 Conduct linkage analyses to identify chromosomal regions QTLs harboring genes that influence individual variation in cardiovascular disease risk factors. Following these linkage analyses, the investigators will examine more closely the strongest linkage signals with fine mapping linkage analysis in order to narrow chromosomal regions of interest. The study is a collaboration between Wright State University and the Southwest Foundation for Biomedical Research. 