<qa>  What is the total duration of the study?In order to improve information provided by neuroimaging, this study aims to investigate prospectively and longitudinally over a period of 6 months white and grey matter lesions in 10 MLD children aged 1 to 6 years, using high-field MRI 3 Teslas and diffusion tensor imaging DTI with 3D reconstruction of the myelin tracks. The time interval between diagnosis and inclusion will not exceed 18 months, thus patients will be included at an early stage of their disease. Each time-point T0 and 6 months will also include neurological evaluation to correlate the imaging, cognitive and motor functions. Children will be included over a period of 5 years. The total duration of the study will be 5.5 years. Controls will include 25 age-matched children with cryptogenic partial epilepsy who should have a high-field MRI to detect structural abnormalities. Controls will have a MRI and cognitive evaluation at T0 and 12 months if necessary. This study will increase our knowledge of the natural history of MLD and provide new indicators for the selection and evaluation of patients eligible for new therapeutic approaches. 