<qa>  What is the first cycle of Induction therapy?Patients will be enrolled into this protocol before start of Induction therapy which consists of 3 cycles or VAD with a 4 week interval followed by 1 cycle of IEV after which stem cell harvesting is performed. After stem cell harvesting is completed Patients will be randomised to one of the high dose therapy arms after response evaluation Complete remission, Partial remission or stable disease. One group is receiving 2 Cycles of Melphalan 200mgm2 each followed by stem cell transplantation, the other group is receiving 3 Cycles of Melphalan 100mgm2 also followed by stem cell transplantation each time. 