<qa>  What is the risk factor for insulin resistance?Obesity and overweight are known risk factors for insulin resistance, which could eventually lead to the development of type 2 diabetes. Since most atypicals as well as schizophrenia itself are likely to induce significant weight gain, it is reasonable to speculate that diabetes associated with atypicals might be secondary to weight changes. However, a number of reasons suggest that factors in addition toor other than weight gain may also be important: 