<qa>  What is the biological efficacy of an association of aspirin and clopidoIn the present study, we will study the biological efficacy of an association of aspirin and clopidogrel 600 mg loading dose followed by 75 mg maintenance dose using an assay measuring ex vivo shear-induced platelet aggregation SIPA, along with other assays measuring platelet activation and aggregation, in order to better describe the heterogeneity of response to antiplatelet agents in patients with DM, MS or no DMMS. 