<qa>  What is the last dose of temozolomide?- Patients must have recovered from severe toxicity of prior therapy; an interval of at least 12 weeks must have elapsed since the completion of radiation therapy or placement of Gliadel wafers, and at least 6 weeks must have elapsed from the last dose of temozolomide TMZ; no prior therapies are allowed other than radiation, temozolomide, and Gliadel wafers placed during the first surgery at diagnosis of GBM 