<qa>  What is the main outcome measure for each biopsy regimen?In this trial mpMRI imaging and CEUS quantification are performed before primary biopsy. Using a fusion device, targeted biopsies are taken from predefined MRI lesions and CEUS lesions, together with standard systematic biopsies in the same patients by separate blinded clinicians. The main outcome measure is the per-patient significant prostate cancer detection rate for each of the biopsy regimens. 