<qa>  What is the effect of IVIR frequency on the oxidative stress formation?In 2004, the committee on the guidelines of the Japanese Society for Dialysis Therapy JSDT published the original Japanese Guidelines for Renal Anemia in Chronic Hemodialysis Patients. In the JSDT guidelines 2004, the committee recommended two IVIR schedules for iron deficient patients; 1 administer 40 mg of IV iron at the end of dialysis session 3 times a week for 4 weeks total 520 mg of iron, 2 administer 40 mg of IV iron at the end of dialysis session once a week for 3 months total 520 mg of iron. Both administration schedules are effective for the correction of iron deficiency and consequently for the amelioration of anemia. However, the effect of IVIR frequency three times a week vs. once a week on the oxidative stress formation has not been investigated before. 