<qa>  What is the name of the type of vascular disease?Radiotherapy to any site within 4 weeks before the study Previous adjuvant oxaliplatin-containing chemotherapy Previous treatment with bevacizumab Untreated brain metastases or spinal cord compression or primary brain tumours History or evidence upon physical examination of CNS disease unless adequately treated Symptomatic peripheral neuropathy 2 grade NCIC-CTG criteria Serious, non-healing wound, ulcer, or bone fracture Evidence of bleeding diathesis or coagulopathy Uncontrolled hypertension and prior histor of hypertensive crisis or hypertensive encephalopathy Clinically significant i.e. active cardiovascular disease for example cerebrovascular accidents 6 months, myocardial infarction 6 months, unstable angina, New York Heart Association NYHA grade II or greater congestive heart failure, serious cardiac arrhythmia requiring medication Significant vascular disease e.g. aortic aneurysm requiring surgical repair or recent arterial thrombosis within 6 months of study enrolment Any previous venous thromboembolism NCI CTCAE Grade 3 History of abdominal fistula, GI perforation, intra-abdominal abscess or active GI bleeding within 6 months prior to the first study treatment. 