<qa>  What should patients have?1. Patients should have clinical and biochemical evidence of hypothyroidism, T4 less than 5.0 ng dl , fT4 less than 1.0 mcgdl and TSH of more than 10. Patients with prolonged hypothyroidism should have growth failure and delayed bone age of at least 2 SD from the mean. Patients with short term hypothyroidism should have normal growth velocity and bone age. 