<qa>  What is NAFLD associated with?The incidence of Non alcoholic fatty liver disease NAFLD continues to increase, and prevalence estimates for NAFLD range from 17-33, making it is the most common cause of chronic liver disease in North America. It is associated with increased cardiovascular morbidity as well as progression to cirrhosis is a subset of patients. There is currently no approved treatment for NAFLD. A key barrier to the development of effective therapies is a lack of consensus on the criteria for diagnosis and endpoints for studies evaluating diagnostic markers, prognosis and therapeutic modalities. 