<qa>  What should be given 3 times daily for 11 days to rapidly lower the plasma level of leflu- Use of DMARDs other than MTX within 4 weeks prior to screening. If a patient had prior exposure to leflunomide within the past 6 months, cholestyramine 8 g should be given 3 times daily for 11 days to rapidly lower the plasma level of leflunomide. 