<qa>  What is the primary aim of the study?This is a single-center, open label study. The primary aim of this project is to develop a controlled human malaria infection transmission model CHMI-trans or challenge model to evaluate the capacity of vaccines, biologics monoclonal antibodies, or mAbs, and drugs to block malaria parasite transmission by assessing infectiousness of Plasmodium falciparum Pf gametocyte carriers for Anopheles mosquitoes. 