<qa>  What is the name of the treatment that can not be on systemic agents?- Cannot be on systemic agents chemotherapy that have CNS penetration unless they develop leptomeningeal metastases while on these agents and have controlled systemic disease. May continue on IV trastuzumab, lapatinib or hormonal agents if controlling systemic disease and developed LM while on therapy. Patients requiring systemic chemotherapy are eligible but will not be able to start treatment until after the first assessment by imaging and cytology. 