<qa>  What is the cytokine cascade that may induce andor support aTopical application of imiquimod induces local interferon-alpha IFN-alpha, interleukin-12 IL-12, and tumor necrosis factor-alpha TNF-alpha, with a resulting cytokine cascade that may induce andor support a cytotoxic T-lymphocyte Th1 immune response. Intralesional IFN-alpha has been shown to be effective for the treatment of BCC. Imiquimod may be an effective therapy for BCC. 