<qa>  What is the type of cardiovascular disease that is not controlled by outpatient medication?- Clinically significant cardiovascular disease within 12 months prior to enrollment or randomization, including myocardial infarction, unstable angina, grade 2 or greater peripheral vascular disease, cerebrovascular accident, transient ischemic attack, congestive heart failure, or arrhythmias not controlled by outpatient medication, percutaneous transluminal coronary angioplastystent 