<qa>  What is the cornerstone immunosuppressant in children with liver transplantation?Tacrolimus is the cornerstone immunosuppressant in children with liver transplantation, its use is complicated by its narrow therapeutic index and variable pharmacokinetics. This study is designed to assess the posology of tacrolimus in post-transplantation in the month after liver transplantation to obtain a therapeutic target between 10-15 ngmL and the impact of biological and genetic factors on the pharmacokinetic parameters in paediatric liver transplant recipients. 