<qa>  What is the propensity to transform to acute myeloid leukemia?Myelodysplastic syndromes MDS are a heterogeneous group of hematologic malignancies of the pluripotent hematopoietic stem cells characterized by clonal hematopoiesis, progressive bone marrow failure, and the propensity to transform to acute myeloid leukemia AML Malcovati et al., 2013. 