<qa>  What is the name of the 3D optic tomography system?Achieved formalin-fixed paraffin embedded tissue specimens from colon cancers andor other benign and pre-cancer colon lesions as well as melanoma andor other benign pigmented skin lesions will be used. The achieved specimens were kept in Department of Pathology, National Taiwan University Hospital. Sections of achieved pathological specimens were put on glass slides and tissue image will be observed by 3D optical coherence tomography OCT. The 3D optic tomography system utilize a Ce:YAG optical fiber as light source and also combined with confocal microscopy. Taken together, these features made the 3D optic tomography system have very high resolution and suitable for single cell imaging. This study will not interfere with the normal medical practice and had no impact on patients safety and health. All of the materials will be destroyed once the experiments are done. The enrollment criteria will be patients who underwent colonskin surgery or examinations in NTUH with pathological specimens taken and stored at NTUH. 