<qa>  What is the ophthalmologic condition that interferes with ophthalmologic examination- Nuclear sclerotic cataract, cortical spoking, posterior subcapsular cataract above Grade 2 per Age Related Eye Disease Study AREDS scale or any other ophthalmologic condition that reduces the clarity of the media that, in the opinion of the investigator or reading center, interferes with ophthalmologic examination example, corneal abnormalities, inadequate pupillary dilation, surgery or imaging in the study eye 