<qa>  What is the name of the drug that can prevent or lessen hand-foot syndrome?RATIONALE: Pyridoxine vitamin B6 and topical urealactic acid-based cream may prevent or lessen hand-foot syndrome caused by chemotherapy. It is not yet known whether giving pyridoxine with or without topical urealactic acid-based cream is more effective than topical urealactic acid-based cream alone or a placebo in preventing hand-foot syndrome. 