<qa>  What is the anti-foaming agent used with mixed success?Intraluminal debris, bile, and air bubbles impair the visibility of small bowel mucosa during VCE. Simethicone, an anti-foaming agent, has been used with mixed success to improve image quality. Three studies investigated the addition of simethicone 30 mg, 600 mg, and 800 mg to overnight fast, PEG, or mannitol demonstrated improvement in visualization with high preparation scores favouring the addition of simethicone.7-9 In contrast, Wei and colleagues 10 compared simethicone 300 mg PEG with PEG alone and found that although simethicone improved visualization, adequate visualization was achieved in only 63 of patients. Similarly, Ge et al. 11 compared simethicone 300 mg against fasting alone and found improvement in visualization with simethicone but this was limited to the proximal half of the small bowel and adequate visualization was limited to 55 of cases. Lastly, Rosa et al. 12 compared simethicone 100 mg PEG with PEG alone and did not find a difference in visualization score. 