<qa>  What is the effect of multiple courses of ANC on the HPA-axis not wellThe effect of multiple courses of ANC on the HPA-axis is not well known. In recent studies a mild adrenal suppression was evident in some of the preterm infants whose mothers received more than eight courses of ANC 15. It has also been proposed that perinatal stress and exposure to corticosteroids induces long lasting changes in HPA-axis and is associated with a decrease in stress induced CRH release in adulthood 24,34. However, there is no existing data about function of HPA-axis in young adults, who have been exposed to antenatal corticosteroids during fetal life. 