<qa>  What is the name of the group that recognizes the A andor B and H antiMore recently we performed a study to determine whether other strains of Noroviruses have a similar pattern of host-specificity and have extended the binding patterns to 7 based on examination of fourteen Noroviruses. The 7 patterns have been classified into two groups according to their interactions with three major epitopes AB, H and Lewis of HBGAs: the AB binding group and the Lewis-binding group. Strains in the AB binding group recognize the A andor B and H antigens, but not the Lewis antigens, while strains in the Lewis-binding group react only to the Lewis andor H antigens. This classification also resulted in a model of the NorovirusHBGA interaction, in which a maximum of two binding sites within a receptor binding interface are involved in NVHBGA interaction. The A, B and H side chains are responsible for binding by the AB binding strains while the Lewis epitopes are responsible for the Lewis binding strains. Phylogenetic analyses showed that strains with identical or closely related binding patterns tended to be clustered, but strains in both binding groups can be found in both genogroups I and II. Our results suggest that Noroviruses have a wide spectrum of host range and human HBGAs play an important role in Norovirus evolution. 