<qa>  What is the most severe form of critical limb ischaemia?It is estimated that 800,000 people in France suffer from peripheral artery disease PAD, of whom 1-2 present the most severe form critical limb ischaemia CLI. In this situation, the patient frequently presents painful non-healing ulcers and focal gangrene. Wound care is generally associated with increasing pain. Pain relief may be challenging in spite of major analgesics. 