<qa>  What will the psychiatrist do after the first 8 weeks of the trial?Each subject will also be allocated to a case manager and a psychiatrist who will be one of the investigators. The psychiatrist in charge of the patient will not be blind to the treatment, and therefore will not do the rating of side effects. A research assistant will conduct all the psychometric assessments across the 12 months of the study and will remain blind to the medication received during the first 8 weeks of the trial. During this eight weeks period, patients will be seen according to clinical needs, and will be met weekly up to week 4 and then on week 6 and 8 for assessment of current levels of psychopathology, the collection of safety data and assessment of compliance. After the first 8 weeks of treatment, the psychiatrist will be free to change the treatment. Neurolpetics will be continued for a minimum of 6 months and lithium for a minimum of 12 months. Lithium serum level will be assessed at day 4 and 7, and then accordingly to the stability of the blood level. 