<qa>  What is the primary outcome of the study?Using a factorial design, this study will compare 1 photocoagulation using a diode micropulse laser to mild Early Treatment Diabetic Retinopathy Studt ETDRS style continuous wave laser using green or yellow wavelength focal photocoagulation and, 2 the effect of treating with antioxidants high dose Vitamin E to placebo prior to and following laser photocoagulation. The primary outcome is a visual acuity drop or increase of 15 letters or more from baseline three year after enrollment. The secondary outcomes will be a 50 reduction in retinal thickening as measured by Optical Cohenrence Tomography OT, a two-step reduction in macular thickness when compared to standard stereoscopic fundus photographs, and a 50 reduction in the area of leakage as measured by fluorescein angiography at 1 year amd 3 years after the initial laser compared to baseline. Additional outcomes will include the time from baseline of the first laser treatment and the number of retreatments required during the course of the study. These outcomes will be assessed for potential use in future trials. We are concerned with the following specific questions regarding safety and efficacy: 