<qa>  What is the name of the two interventions that are included in the diagnosis of major depression?40 patients with the diagnosis of major depression are included. There are two interventions: partial sleep deprivation PSD and normal night sleep CTRL. Patients are randomly assigned to PSD-2 undisturbed nights-CTRL or CTRL-2 undisturbed nights-PSD. Cytokine-status, neuropsychological and psychopathometric status are assessed pre and post each interventional and control condition. 