<qa>  What is the TDI echocardiography used?vi Abnormal LV size with systolic and diastolic dysfunction in pre dialysis CKD patients: In a group of 18 consecutive stable stage 4 and 5 CKD patients, deemed suitable for renal transplantation, the investigators have seen significant increase in LVM, interventricular septal IVS diameter and posterior wall diameter with systolic and diastolic dysfunction; using a combination of Transthoracic and Cardiac Tissue Doppler Imaging TDI echocardiography, compared to normal controls. 