<qa>  What is the goal of the Phase Ia part of this trial?The aim of the Phase Ia dose escalation part of this trial is to assess the MTD of BI 847325 administered at escalating doses in 2 treatment arms. In the Phase Ib expansion part of the trial, the aim is to further evaluate the safety profile of BI 847325 at the recommended dose and schedule and to assess target modulation and the potential antitumour efficacy in patients with selected tumour types. 