<qa>  What is the safety or efficacy of serial courses of glucocorticoiClinical practice administering antenatal corticosteroids varies greatly between individual centers during the late 1990s. The practice of repeating the course of ANC has become widespread. However the safety or efficacy of serial courses of glucocorticoid is not known. According to recently published non-randomized studies there is conflicting data on growth and neonatal morbidity of infants exposed to single vs. multiple course of ANC 13,14,15. There is also concern particularly in women with prolonged premature rupture of fetal membranes PPROM that repetitive doses may increase maternal and fetal infections 21,22. In a retrospective study the multiple course of ANC was associated with an increased incidence of maternal postpartum infections 13. 