<qa>  What is the most common type of AE?Diagnosis of angioedema AE is difficult especially in emergency room. Two forms should be evoked: histaminic AE allergic or not, which represent 95 of cases and bradykinic AE hereditary or acquired deficiency, with or without C1 Inhibitor rarer but with more severe prognosis. The distinction is based on clinical features spontaneous crisis duration, presence of concomitant hives, atopic history.... Sometimes it could be difficult to make the difference. Nowadays, there is no biological marker of the crisis. The search for biomarkers could improve the diagnostic and therapeutic management of AE. Previous work has identified targets: D-dimer, C4, and VE-cadherin. We wanted to know the sensitivity and specificity of these markers. 