<qa>  What is the maximum amount of bilirubin?5. Patients must have adequate hepatic, renal, and bone marrow function as defined below: 1 Serum creatinine 1.5 mgdL or a calculated creatinine clearance 60 mLmin 2 Total bilirubin 1.5 x ULN 3 ALT or AST 2.5 x ULN OR ALT or AST 5.0 x ULN if related to liver metastases OR Alk Phos 2.5 x ULN 4 WBC 3,000mm3 5 ANC 1,500 mm3 6 Platelets 100,000mm3 7 Hemoglobin 10 gdL 8 PTPTT 1.5 x normal 