<qa>  How many biopsies will be obtained at surgery?Core biopsies: Core biopsies for biologic marker evaluation will be performed prestudy excess from diagnostic biopsy, and on days 2, 8, 15, and 22 following entry into study. Tissue for analysis will also be obtained at surgery. Prestudy biopsy and specimen at surgery will be part of standard of care, while four additional biopsies will be performed solely for research purposes only. Thus, a total of six biopsies will be obtained: prestudy, day 2, day 8, day 15, day 22, and at surgery. 