<qa>  What is a type of therapy that is not considered a systemic treatment?- Active autoimmune disease that has required systemic treatment in the past 2 years ie, with use of disease-modifying agents, corticosteroids, or immunosuppressive drugs. Replacement therapy eg, thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc. is not considered a form of systemic treatment 