<qa>  What is the effect of pioglitazone on endothelial function inThe present study aims to investigate the effect of pioglitazone 30 mgday on endothelial function in premenopausal women with SLE systemic lupus erythematosus. Patients with hypertension, endocrine, hepatic or renal diseases will not be included, or pregnant breast feeding women. This is a randomized, double blind, placebo controlled study. 