<qa>  What is the endogenous thrombin potential?Specific Aim 1: The endogenous thrombin potential ETP is the area under the curve of the thrombin generation assay. The values are continuous and range from 0 to 2,500. Maximum clot formation MCF from the roTEG will also be used to approximate ETP. The DIC score will be calculated and coded as a dichotomous variable: Yes score 5 or No score 5. A receiver operating curve will be derived for ETP and MCT and its sensitivity and specificity for predicting DIC. If the area under the curve is found to be significant, an optimal cut-off value with the highest degree of accuracy will be chosen. This value will be used to estimate the predictive value of the test. Positive predictive value will be calculated with the formula: patients with ETP or MCT above the cut-off and development of DIC patients with positive DIC score. The predictive value of a negative DIC score will be calculated using the formula: patients with ETP or MCT below the cut-off and no progression to DIC patients with negative DIC score. 