<qa>  What is the multicenter prospective cohort evaluation of the implementation of a cryptococcal antiThis is multicenter prospective cohort evaluation of the implementation of a cryptococcal antigen CrAg screening program in Vietnam. HIV-infected patients with CD4 100 cellsμL who present for HIV care at outpatient clinics OPCs in Vietnam where CrAg screening is offered will be recruited into the study. Study participants will be screened for cryptococcal antigen using the Lateral Flow Assay LFA and followed up for 12 months with clinical assessments and the collection of routine and supplemental survey data. Those who are CrAg-positive, but have no features of central nervous system CNS disease, will be treated with high-dose fluconazole. Those with symptoms of CNS disease will be treated according to national guidelines. Survival, retention in care, and other clinical outcomes will be documented for patients who test CrAg-positive and are treated with fluconazole and those who test CrAg-negative. 