<qa>  What is the focus of the present study?The focus of the present study is to evaluate the usefulness of cidofovir injection in diminishing the frequency and magnitude of papilloma recurrences in adult and pediatric RRP patients. Briefly, patients will be randomized into either a treatment cidofovir injection or a placebo group. The following measures will be made at each of 6 data collection time points, over the course of one year: 1 tumor load, based upon a published staging system for papilloma, 2 degree of respiratory obstruction for phonation, as assessed by phonation threshold pressures, and 3 general health, on validated health inventories SF12 and Voice Handicap Index for adults; PedsQL Trademarked for children and via measures of height weight and days absent from school or daycare, where applicable, for children. A repeated measures analysis will allow examination of time by treatment interactions to determine if the cidofovir injection group has fewer, or less severe, recurrences than the placebo group. 