<qa>  What is the name of the nucleoside analogues?Chronic hepatitis B is a major health problem, affecting more than 350 million people worldwide. 1 First line treatment consists of pegylated IFN once weekly or oral nucleostide analogues NA once daily. 2 NA target the reverse transcriptase of hepatitis B virus HBV, and are potent inhibitors of viral replication. In the absence of antiviral drug resistance, continued NA therapy is able to suppress viral replication over prolonged periods, and can prevent clinical progression to liver cirrhosis and hepatocellular carcinoma. 3 Currently approved agents include the nucleoside analogues lamivudine LAM, telbivudine LdT, and entecavir ETV, and the nucleotide analogues adefovir dipivoxil ADV, and tenofovir disiproxil fumarate TDF. 