<qa>  What is the name of the positive confirmatory test for HIV infection?All subjects who meet any of the following exclusion criteria at baseline will be excluded from participation in the study. 1. Has had known infection due to S. mansoni or has traveled to an endemic area for S. mansoni infection and, during that travel, was potentially exposed to S. mansoni. 2. Has a positive urine pregnancy test prior to vaccination if female of childbearing potential, or has the intention to become pregnant within 5 months after enrollment in this study. 3. Female subjects who are breastfeeding or plan to breastfeed at any given time from the first study vaccination until 30 days after their last study vaccination. 4. Has an acute illness, including an oral temperature of 100.0 degree F or greater, within 72 hours prior to vaccination. 5. Evidence of clinically significant neurologic, cardiac, pulmonary, hepatic, rheumatologic, autoimmune, diabetes, or renal disease by history, physical examination, andor laboratory studies. 6.6 Includes the conditions and diagnoses defined as AESI in Section 9.3.3. 6. Is immunosuppressed as a result of an underlying illness or treatment.7.7 Causes for immunosuppression may include, but are not limited to, poorly-controlled diabetes mellitus, cirrhosis, renal insufficiency, active neoplastic disease or a history of any hematologic malignancy, connective tissue disease, organ transplant. 7. Using or intends to continue using oral or parenteral steroids, high-dose inhaled steroids 800 microgday of beclomethasone dipropionate or equivalent or other immunosuppressive or cytotoxic drugs. 8. Positive hepatitis B surface antigen HBsAg 9. Positive confirmatory test for HIV infection 10. Positive confirmatory test for hepatitis C virus HCV infection 11. Volunteer has had a history of alcohol or illicit drug abuse during the past 24 months. 12. Received immunoglobulin or other blood products with exception of Rho D immunoglobulin within 90 days prior to study vaccination. 13. History of a severe allergic reaction or anaphylaxis to known components of the vaccine 14. Has an acute or chronic medical condition that, in the opinion of the investigator, would render participation in this study unsafe or would interfere with the evaluation of responses. Note: This includes, but is not limited to: known liver disease, renal disease, neurological disorders, visual field defects, cardiac disorders, pulmonary disorders, diabetes mellitus, and transplant recipients. 15. History of splenectomy 16. Plans to undergo surgery elective or otherwise from the time of enrollment through 1 month post dose 3 vaccination. 17. Is participating or plans to participate in another clinical trial with an interventional agent9 during the duration of the study. Note: This may include other licensed or unlicensed vaccines, drugs, biologics, devices, blood products, or medications. 18.Received any licensed live vaccine within 30 days or any licensed inactivated vaccine within 14 days prior to the first study vaccination. Note: During influenza season, subjects will be offered seasonal influenza vaccine prior to enrollment into the study. 19. Planned receipt of any vaccine from the first study vaccination through 1 month after the last study vaccination. 20. Have any diagnosis, current or past, of schizophrenia, bipolar disease, or other psychiatric diagnosis that may interfere with subject compliance or safety evaluations. 21. Has any condition that would, in the opinion of the site investigator, place the subject at an unacceptable risk of injury or render the subject unable to meet the requirements of the protocol. 