<qa>  What is a low dose warfarin with PT-INR?- Low dose warfarin 1 mg orally, once daily with PT-INR 1.5 x ULN is permitted. Infrequent bleeding or elevations in PT-INR have been reported in some subjects taking warfarin while on regorafenib therapy. Therefore, subjects taking concomitant warfarin should be monitored regularly for changes in PT, PT-INR or clinical bleeding episodes. 