<qa>  What is a relapsing disease?3. Unsatisfactory course despite 3 immunosuppressive agents usually azathioprine, methotrexate and infliximab in addition to corticosteroids. Patients should have relapsing disease i.e. 1 exacerbationyear despite thiopurines, methotrexate andor infliximab maintenance therapy or clear demonstration of intolerance toxicity to these drugs. 