<qa>  What is a female participant must be?- A female participants must be either: a Not of childbearing potential: postmenopausal greater than 45 years of age with amenorrhea for at least 2 years, or any age with amenorrhea for at least 6 months and a serum follicle stimulating hormone FSH level 40 international UnitLiter IUL; OR b Permanently sterilized example, bilateral tubal occlusion which includes tubal ligation procedures as consistent with local regulations, hysterectomy, bilateral salpingectomy, bilateral oophorectomy or otherwise incapable of becoming pregnant; OR c If of childbearing potential and heterosexually active, be practicing an effective method of contraception before entry and agree to continue to use two effective methods of contraception throughout the study and for at least 90 days after receiving the last dose of study drug 