<qa>  What is the PIs opinion that is acceptable for adoptive cell therapy?- Must have unresectable cutaneous or mucosal metastatic stage IIIIV melanoma, and in the opinion of the institutional principal investigator PI is an acceptable candidate for adoptive cell therapy ACT with high dose IL-2. Patients with mucosal metastatic melanoma may be included, as our prior experience indicates that TIL can be successfully propagated from these subtypes of melanoma metastases. 