<qa>  What is the term for acne treatment that does not have significant or measurable systemic absorption3. Willing to refrain from using any treatments, other than the investigational product, for acne present on the face. This includes the use of antibiotics for the treatment of acne. Topical acne treatments that do not have significant or measurable systemic absorption e.g., benzoyl peroxide, salicylic acid are allowed for treatment of non-facial acne. 