<qa>  What is the difference in osteoconductivity and osteoinductivity between the available DBMDBMs are manufactured by different companies and they are available in different presentations. Most important, they vary also in their efficacy. The efficacy of a DBM depends mainly on it osteoconductivity and osteoinductivity 1,5. The differences in osteoconductivity and osteoinductivity between the available DBMs could represent a factor that limits the hosts response to the graft 12. According to Louis-Ugbo et al, even the different presentations of DBMs could cause different host responses. 11 This is why it is very important to find a DBM that not only is highly effective, but also has the adequate presentation to be use in trauma fracture patients that require an acute treatment. In a study done by Cammisa et al they asseverate that the value of Grafton is based upon not only the high osteoconductivity and osteoinductivity that the product presents, but also the fact that the gel formulation allows a mixture with allograft that helps to reach difficult graft sites 3. Other studies have shown that the putty presentation of Grafton could be even higher in inductive properties 3. A previously done study at Grady Hospital conducted by our service reported an enhanced fracture healing in high energy tibial fractures treated with percutaneous injection of bone marrow with Grafton acutely reference to be inserted. Our experience support the hypothesis that Grafton could be also valuable in the treatment of closed tibia diaphyseal fractures, with a smaller healing frame, decreased hospitalization time and early return to work. 