<qa>  What is one of the most commonly used IBS medication worldwide?Pinaverium bromide pinaverium, an antispasmodics, is one of the most commonly used IBS medication worldwide. However, original clinical studies on pinaverium are scarce. Only five original clinical studies from Europe, one from Latin America, and one from Asian were found. These studies were single-centered and small sample sized 19 - 53 IBS patients studies. 