 Ebe ọ bụ na ha abụọ nwere ike igbochi estrogen na hypothalamus na pituitary, si otú ahụ kwusi mmechi nkwụsị na-ezighị ezi, anyị nwere ọgwụ ọjọọ nke nwere ike ịbawanye FSH hormone na-akpali akpali na LH luteinizing hormone nime ahụ nwoke. 