<prompt> Comment on the diagnosis?Down syndromeTurner syndromePrader-Willi syndromePatau syndrome  <response>: Ans. a Down syndrome.Notice the hypotonia with facial grimace and a wide gap between the first and second toe of the foot. The karyotype confirms it to be trisomy 21.Mnemonic for DOWN Syndrome is CHILD HAS PROBLEM Cataractsheart disease Endocardial cushion defect Hypotoniahyperthyroidism Incur 5th fingerIncreased gap between 1st and 2nd toes Leukemia risk x 2Lung problems Duodenal atresiaDelayed development Hirschsprungs diseaseHearing loss Alzheimers diseaseAtlantoaxial instability Short neckSquint Protruding tonguePalmar crease Round faceRolling eye nystagmus Oblique eye fissureOcciput flat Behavioral difficulties Low nasal bridgeLanguage problem Epicanthic foldEar folded Mental retardationMyoclonusImage source- stylefont-family: Times New Roman, Times, serif 