<prompt> Most common malignancy of the endocrine system?Thyroid cancerPancreatic cancerPituitary adenomaAdrenal malignancy  <response>: Ans. a Thyroid cancerRef: Harrison 18th ed. 341 Thyroid carcinoma is the most common malignancy of the endocrine system. Differentiated tumors, such as papillary thyroid cancer PTC or follicular thyroid cancer FTC, are often curable, and the prognosis is good for patients identified with early-stage disease. In contrast, anaplastic thyroid cancer ATC is aggressive, responds poorly to treatment, and is associated with a bleak prognosis. 