<prompt> ed maternal serum a-FP is seen in :Multiple pregnancyTrisomy 21Open neural tube defectIUD  <response>: Ans. is b i.e. Trisomy 21Low levels of MSAFP Maternal serum alpha feto protein are seen in :Chromosomal trisomyGestational trophoblastic diseasesBlighted ovumIncreased maternal weightOverestimated gestational age. 