<prompt> A patient presents to a physician because of pain during defecation accompanied by blood in the stool. Physical examination demonstrates a large perianal mass. Pathologic examination of the rectal mass following resection demonstrates a condyloma in which transformation to frank carcinoma has occurred. Which of the following viruses would most likely be associated with these lesions?Epstein-Barr virus EBVHepatitis B virus HBVHuman herpesvirus type 8 HHV8Human papillomavirus HPV  <response>: The tumor is anal carcinoma arising in a condyloma. Both condyloma and anal carcinoma are related to human papilloma virus HPV, which is also associated with cervical and penile condylomas and carcinomas. EBV is associated with Burkitts lymphoma and nasopharyngeal carcinoma. HBV is associated with hepatocellular carcinoma. HHV 8 is associated with Kaposis sarcoma. Ref: Ray C.G., Ryan K.J. 2010. Chapter 19. Papilloma and Polyoma Viruses. In C.G. Ray, K.J. Ryan Eds, Sherris Medical Microbiology, 5e. 