<prompt> Which of the following laboratory determinants is abnormally prolonged in ITP?APTTProthrombin timeBleeding timeClotting time  <response>: Immune thrombocytopenic purpura is an acquired disorder characterized by immune-mediated destruction of platelets and inhibition of release of platelets from the megakaryocyte. Since plateletsare involved bleeding time is abnormally prolonged in ITP. APTT, PT, CT are prolonged in coagulation disorders. Ref: Harrisons Principle of Internal Medicine, 18th Edition, Page 968, Chapter 115 