<prompt> Kaposi sarcoma is commonly seen in -Upper limbsLower limbsHead and NeckTrunk  <response>: DFSP is a low-grade sarcoma because it may recur locally but rarely metastasizes. Monomorphous, mononuclear, spindle cell lesion involving both dermis and subcutis. MC site: Trunk 50 Extremities 30 Head and neck 20Pathology Large lesions often are associated with satellite nodules; Positive for CD34 Have unpredictable radial extensions of tumor permeating through the subcutaneous tissue large distances from the primary nodule. More than 75 of DFSP have a ring chromosome, composed of translocated portions of chromosomes 17 and 22Clinical Features Typically presents in early or mid-adult life, beginning as a nodular cutaneous mass. Pattern of growth: Slow and persistent Lesion enlarges over many years, it becomes protuberantTreatment Aggressive resection with special attention to radial margins local recurrence rate 5 Up to 50 recur after simple excision. Imatinib: First line of treatment for advanced disease. 