<prompt> Earliest change in diabetic retinopathy isHyaloid changeHard exudateMicroaneurysms and pin point haemorrhagesVitreous haemorrhage  <response>: C Microaneurysms and pin point haemorrhages Non-proliferative diabetic retinopathy NPDR Ophthalmoscopic features of NPDR include: Microaneurysms in the macular areathe earliest detectable lesion. Retinal haemorrhages both deep dot and blot haemorrhages and superficial haemorrhages flame-shaped. Hard exudates -yellowish-white waxy-looking patches are arranged in clumps or in circinate pattern. These are commonly seen in the macular area. Retinal oedema characterised by retinal thickening. Cotton-wool spots if8, there is high risk of developing PDR. Venous abnormalities, beading, looping and dilatation. Intraretinal microvascular abnormalities IRMA. Dark-blot haemorrhages representing haemorrhagic retinal infarcts. 