<prompt> Most common cause of malignant poal vein thrombosis is:Renal cell carcinomaCarcinoma prostateHepatocellular carcinomaCarcinoma colon  <response>: Malignancies are responsible for 21-24 of overall cases of PVT. Among them hepatoma accounts for majority followed by pancreatic malignancy. PVT is common in patients affected by liver cirrhosis. Ref: World J Gastroenterol 2010 January 14; 162: 143-155. 