<prompt> Post-streptococcal glomerulonephritis is associated with -Follows skin and throat infectionAntibiotic treatment induces remissionIs a cause of chronic renal failure in majority of childrenAll  <response>: Ans. is a i.e., Follows skin and throat infection Post streptococcal glomerulonephritis o PSGN appears 1 to 4 weeks after a streptococcal infection of pharynx or skin impetigo. It is caused by ceain nephritogenic serotypes of group A f3-hemolytic streptococcus not by all serotypes. o The lesions are caused by immune complex deposition and activation of complement -- complement level decreases. It occurs most frequently in children 6 to 10 years of age. o Clinically child presents with acute nephritic syndrome ? i Hematuria iii Azotemia v Hypeension ii Oliguric acute renal failure iv Proteinuria vi Edema o PSGN causes acute renal failure, but not chronic renal failure - more than 95 of affected children eventually recover totally with conservative therapy. Treatment Management is directed at treating the acute effects of renal insufficiency and hypeension. o Although a 10 day course of systemic antibiotic therapy with penicillin is recommended to limit the spread of nephritogeric organisms, antibiotic therapy does not affect the natural history of glomerulonephritis. 