<prompt> 4 year old male child had febrile seizures, best prophylaxis -Paracetamol 6 hourlyParacetamol diazepamDiazepamPhenobarbitone  <response>: Ans. is c i.e., Diazepam Prophylaxis in febrile seizures Prophylactic anticonvulsants are not given routinely in febrile seizures. They are required when ? i Febrile seizure is prolonged or complicated ii Medical reassurance fails to relieve family anxiety. Prophylaxis may be continuous or intermittent Intermittent prophylaxis o It is currently the desirable form of therapy o It is used during episodes of fever o Indicated during first three days of fever. o Drugs that are used are - Diazepam and other benzodiazepenes these drugs are used because they attain desired levels quickly Diazepam is given oral or rectal. Continuous prophylaxis - o It is used when Intermittent therapy has failed Recurrent atypical seizures Central nervous system disease Family history of epilepsy o Drugs used are -- Sodium valproate or phenobarbitone. Note - Carbamazepine and phenytoin are ineffective for prevention of recurrence. 