<prompt> Cytogenetics for synovial cell sarcoma is -t X : 18t 17, 9t 9, 22t 11,14  <response>: Synovial cell Sarcoma SCS Synovial cell sarcoma forms about 10 of all soft tissue sarcomas.Although the name suggests an origin from the synovial linings, less than 10 of them are intra-articular.Most synovial sarcomas show a characteristic chromosomal translocation t X: 18 producing SYT-SS X1 or - SS X2 fusion genes. The specific translocation is associated with poor prognosis.60-70 of SCS involve the lower extremities, especially around knee and thigh.Histologic hallmark of biphasic synovial sarcoma is the dual lining of differentiation of the tumor cells eg. epithelial like and spindle cells.Calcified concretions can be present on X-rays.This tumor is positive forKeratinEpithelial membrane antigen. 