<prompt> A 56-year-old woman has nausea due to chemotherapy for breast cancer. Droperidol is effective in reducing nausea because it blocks wof5-HT 2 receptors in the CTZGlucocoicoid receptors in the vomiting centerDopamine receptors in the CTZACh receptors in the periphery  <response>: NEUROLEPTICS The older neurolepticsphenothiazines, haloperidol are potent antiemetics; act by blocking D2 receptors in the CTZ; antagonize apomorphine induced vomiting and have additional antimuscarinic as well as H1 antihistaminic propey. They have broad spectrum antiemetic action effective in: a Drug induced and postoperative nausea and vomiting PONV. b Disease induced vomiting: gastroenteritis, uraemia, liver disease, migraine, etc. c Malignancy associated and cancer chemotherapy mildly emetogenic induced vomiting. d Radiation sickness vomiting less effective. e Morning sickness: should not be used except in hyperemesis gravidarum. Ref:- kd tripathi; pg num:-664 