<prompt> Primary Structural defect of an organ is termed:MalformationDisruptionDeformationAssociation  <response>: Primary structural defect of an organ is called as malformation. Primary malformations are caused by endogenous disturbances of the primordial tissues. Secondary malformations disruptions arise when organs develop abnormally from a normal primordium. Ref: Tanley L. Robbins, Ramzi S. Cotran, 2012 , Chapter 1, Cell Injury, In the book, Pocket Companion to Robbins and Cotran Pathologic Basis of Disease, 8th Edition, USA, Page 27 ; Robbins Basic Pathology, 7th Edition, Pages 470-71 