<prompt> In the treatment of hypothyroidism, thyroxine is preferred over liothyronine because thyroxine:Is faster actingHas higher affinity for thyroid hormone receptorsHas a longer half lifeCan be made more easily by recombinant DNA technology  <response>: Ref: KDT 6e p247 Liothyronine T3 as compared to thyroxine T4 is: Fast acting More potent Sho half life Indication of liothyronine includes myxedema coma and for most of the indications thyroxine is used because is has a long half life thus can be used less frequently than T3. 