<prompt> Uncommon complication of meckels diveiculum is:September 2005IntussusceptionDiveiculitisMalignancyIncreased bleeding  <response>: Ans. C: MalignancyEpidemiology- More common in males by ratio of 3:2Lifetime complication rate: 4- More than 50 of complications occur before age 10History-Initial repo by Hildanus in 1598, Detailed description by Johann Meckel in 1809Pathophysiology: Meckels Diveiculum- Incomplete vitelline duct omphalomesenteric closure- Location. Proximal to ileocecal valve by 100 cmUsually within 45 to 60 cm of ileocecal valveDifferential Diagnosis of Meckels Diveiculitis-AppendicitisComplications of Meckels Diveiculum- GI Bleeding 25-50 of complicationsOften associated with ectopic gastric mucosaHemorrhage is most common presentation under age 2- Meckels Diveiculitis 10-20 of complications-Similar in presentation to Appendicitis- Bowel ObstructionVolvulus at fibrotic band attached to abdominal wallIntussusceptionIncarcerated Inguinal Hernia Littres hernia- Other complications-Carcinoid TumorRadiology- Radionuclide Scintigraphy Sodium Tc-peechnetatePreferential uptake by gastric tissueMost accurate test in Meckels Diveiculum-Test Sensitivity is 85 in children and Test Specificity is 95 in childrenLess accurate in adults -Cimetidine increases accuracy in adults- Small bowel enema-Indicated for negative scintigraphy in adults- Aeriography indicated for acute hemorrhage 