<prompt> Which of the following condition is true about Barrett oesophagusSquamous to coulmanr metaplasiaCoulmanr to squamous metaplasiaDoes not increase risk of malignancyNone of the above  <response>: Refer Robbins page no Pg 7579e Damage to the lower poion of the tube that connects the mouth and stomach oesophagus. Barretts oesophagus is usually the result of repeated exposure to stomach acid. Its most often diagnosed in people with long-term gastro-oesophageal reflux disease GERD. The protein AGR2 is elevated in Barretts esophagus and can be used as a biomarker for distinguishing Barrett epithelium from normal esophageal epithelium. The presence of intestinal metaplasia in Barretts esophagus represents a marker for the progression of metaplasia towards dysplasia and eventually adenocarcinoma 