<prompt> A HIV patient presents with cough for 10 days. Sputum culture with SDA reveals broad budding yeast with thick mucoid wall. Diagnosis:BlastomycosisHistoplasmosisCoccidiomycosisPenicillium marneffi  <response>: Microscopic pictures shows broad budding yeast with figure of 8 appearence seen in Blastomycosis. Blastomycosis can present in one of the following ways: a flu-like illness with fever, chills, ahralgiajoint pain, myalgiamuscle pain, headache, and a non productive cough which resolves within days. skin lesions, usually asymptomatic, can be verrucous wa-like or ulcerated with small pustules at the margins. bone lytic lesions can cause bone or joint pain. 40 immunocompromised individuals have CNS involvement and present as brain abscess, epidural abscess or meningitis. Histoplasmosis - tiny oval yeast cell with narrow based budding Coccidiomycosis - spherules are seenlarge sac filled with endospore Penicillium marneffi - oval or elliptical cell with central septation 