<prompt> HIV virus has a paicularly high affinity for which of the following?CD4 T Lymphocytes and B cellsCD4 T Lymphocytes and monocytesCD8 T Lymphocytes and B cellsCD8 T Lymphocytes and CD4 T Lymphocytes  <response>: HIV has a paicular tendency to bind to CD4 T lymphocytes helper T lymphocytes and monocytes and then become internalized. Most other cells, include CD8 T lymphocytes suppressor T cells and B cells, are not paicularly susceptible to the HIV virus. HIV preferentially infects and kills helper CD4 T lymphocytes, resulting in the loss of cell-mediated immunity and a high probability that the host will develop oppounistic infections. Other cells e.g., macrophages and monocytes that have CD4 proteins on their surfaces can be infected also. Also know: The genome of HIV consists of two identical molecules of single-stranded, positive-polarity RNA and is said to be diploid. In addition to the three typical retroviral genes gag, pol, and env, which encode the structural proteins, the genome RNA has six regulatory genes. Two of these regulatory genes, tat and rev, are required for replication, and the other four, nef, vif, vpr, and vpu, are not required for replication and are termed accessory genes. Ref: Levinson W. 2012. Chapter 45. Human Immunodeficiency Virus. In W. Levinson Ed, Review of Medical Microbiology Immunology, 12e. 