<prompt> Liver biopsy is indicated in patients with hemochromatosis only if:Elevation of transaminase presentSerum ferritin 1000 gLEvidence of cirrhosisIf percentage saturation of iron is high  <response>: Screening tests for hemochromatosis are: transferrin saturation or ferritin level Both will be high Confirmatory test for hemochromatosis: Genetic testing C282Y homozygote or a compound heterozygote C282YH63D. If the ferritin is 1000 gL, the patient should be considered for liver biopsy. Ref: Harrison, E-18, P-2603. 