<prompt> Therpeutic drug monitoring is particularly useful for which of the following drugs?LithiumAminoglycoside antibioticsAnticonvulsantsAll the above  <response>: Ans. is d i.e., All the above Therapeutic drug monitoring is particularly useful in following situations:1. Drugs with low safety margin -a Digoxinb Anticonvulsantsc Antiarrythmicsd Theophyllinee Aminoglycoside antibioticsf Lithiumg Tricyclic antidepressants2. If individual variations are large - Antidepressants, Lithium3. Potentially toxic drugs used in presence of renal failure - Aminoglycoside antibiotic vancomycin, cyclosporine4. In case of poisoning5. In case of failure of response without any apparent reason - antimicrobials6. To check patient compliance - psycho-pharmacological agents. Drugs whose response is easily measurable eg. hypoglycaemics metformin, antihypertensive, diuretics, oral anticoagulants and general anaesthetics, monitoring of plasma cone, is of no value. 