<prompt> Minimum effective dose of Ethinyl estradiol in combination oral pills is20 pgm35 pgm50 pgm75 pgm  <response>: Ans. is a i.e. 20p.g -intensive pharmacological research clinical trials conducted to minimise the adverse effects of estrogen without reducing the contraceptive efficacy, resulted in lowering the dose of oestrogen to a minimum of 20gg or even 15gg. Examples of pills with 20p.g estrogen : Femilon : Loette Estrogen EE 2opg Estrogen EE 20pg Progestin Desogestrel 0.15mg Progestin Levonorgestrel 0.1mg Benefits of Low dose OCPs Decreased risk of Thromboembolic events with low dose OCPs.deg Note : Thrombosis risk is apparent by 4 months after staing estrogen containing OCs and does not increase fuher with continued use. Risk is highest during the first year of useq Decreased risk of high blood pressure as compared to traditional high dose OCPs Minimum adverse effect on lipid profile Less complains of Nausea and vomiting as these complications are related to Estrogen component. The beneficial effects and efficacy of low dose OCPs is similar to traditional high dose OCPs whereas side effects have decreased. Extra Edge : Once a month long acting pill. Contains : Ouniestrol long acting estrogen sho acting progestin. 