<prompt> Which is not a feature of paroxysmal nocturnal hemoglobinuria -Increased LAP scoreThrombosisThrombocytopeniaHemolysis  <response>: Clinical features of PNHA. Intravascular hemolysisThe main feature of PNI-I is increased intravascular hemolysis that results inHemoglobinemia Hemoglobinuria HemosiderinuriaIncreased urine urobilinogen Decreased serum haptoglobin Increased serum LDH Increased serum bilirubinThe hemolysis is paroxysmal and usually occurs in the night because during sleep the pH of blood gets slightly reduced and acidic medium leads to activation of the complement.B. ThrombosisIn PNH there is episodic thrombosis due to the absence of CD-59 on platelets, this results in the externalization of phosphatidylserine, a site for prothrombinase complexes and thus increase the propensity for thrombosis.Intrabdominal veins are the most common sites of thrombosis that may result in Budd Chiari syndrome due to hepatic vein thrombosis.C. Other featuresThrombocytopeniaGranulocytopeniaDecreased LAP scoreNormoblastic hyperplasia of bone marrowPNH patients are also at increased risk for developing acute myelogenous leukemia and aplastic anemia. 