<prompt> Cerebral malaria is caused by-P. falciparumP. vivaxP. ovaleNone of the above  <response>: Ans. is a i.e., P. falciparum Cerebral malaria is a manifestation of severe falciparum malaria. Other manifestations of severe falciparum malaria areManifestations of severe falciparum malariaSignsManifestationsMajorUnarousable coma cerebral malariaFailure to localize or respond appropriately to noxious stimulf; coma persisting for 30 min after generalized convulsionAcidemiaacidosisArterial pH of 7.25 or plasma bicarbonate level of 15 mmolL; venous lactate level of 5 mmolL; manifests as labored deep breathing, often termed respiratory distressSevere normochromic, normocytic anemiaHematocrit of 15 or hemoglobin level of 50gL 5 gdL iwth parasitemia level of 100,000 mlRenal failureUrine output 24 h of 400 mL in adults or 12 mLkg in children; no improvement with rehydration; serum creatinine level of 265 mmolL mgdLPulmonary edema adult respiratory distress syndromeNoncardiogenic pulmonary edema, often aggravated by overhydrationHypoglycemiaPlasma glucoss level of 2.2 mmolL 40 mgdLHypotensionshockSystolic blood pressure of 50 mmHg in children 1-5 years or 80 mmHg in adults; core skin temperature difference of 10degC; capillary refill 2 sBleeding disseminated intravascular coagulationSignificant bleeding and hemorrhage from the gums, nose, and gastrointestinal tract and or evidence of disseminated intravascular coagulationConvulsionsMore than two generalized seizures in 24 h; signs of continued seizure activity sometimes subtle e.g., tonic-clonic eye movements without limb or face movementHemoglobinuriaMacroscopic black, brown, or red urine; not associated with effects of oxidant drugs and red blood cell enzyme defects such as G6PD deficiencyOtherImpaired consciousness arousableUnable to sit or stand without supportExtreme weaknessProstration; inability to sit unaidedHyperparasitemiaParasitemia level of 5 in nonimmune patients 20 in any patientJaundiceSerum bilirubin level of 50 mmol 3 mgdL if combined with other evidence of vital-organ dysfunction 