<prompt> All of the following statement about pralidoxime in organophosphate poising are true exceptIt is given IntravenouslyIt should be staed after 24 hrs. of poisoningDoes not cross blood brain barrierReactivates AchE enzyme  <response>: - Oximes are given for the reactivation of the inhibited Acetylcholinesterase in OPC poisoning - Two oximes which are used : PAM Pralidoxime : does not cross blood brain barrier DAM Diacetyl mono-oxime : crosses blood brain barrier, both central and peripheral action - Oximes should be staed as soon as possible after atropine is given , if we take long time then enzyme aging may occur enzyme cannot work 