<prompt> Antidote for opioid poisoning;NaloxonePethidineFlumazenilPhysostigmine  <response>: Naloxone is an opioid antagonist given intravenously. It blocks mu, kappa and delta receptors. It is the DOC for opioid toxicity. is given parenterally ineffective orally and is a very sho acting drug. Pethidine Meperidine- fully agonist at opiod receptors Flumazenil-Flumazenil is specific antidote for benzodiazepines. Physostigmine - it is a lipid soluble anticholinesterase. It is the specific antidote for poisoning with belladonna. 