<prompt> The diuretic group that does not require access to the tubular lumen to induce diuresis is ?Carbonic anhydrase inhibitorNa-Cl sympo inhibitorMineralocoicoid antagonistNa-K sympo inhibitor  <response>: Ans. is c i.e. Mineralocoicoid antagonist Spirinolactone is mineralocoicoid aldosterone antagonist. It opposes the action of Aldosterone without requiring access to the tubular lumen. Spirinolactone as well as aldosterone act from the interstitial side. 