<prompt> What is the most impoant role of bradykinin in acute inflammation-Increase in vascular permeabilityVasodilatationMediation of painBronchoconstriction  <response>: Functions of Bradykinin: Increases vascular permeability Contraction of smooth muscles Dilation of the blood vessels Pain when injected into the skin Out of these actions of bradykinin, the increase in vessel permeability is a better answer as it is the hallmark of acute inflammation ref robbins9th ed page 52 