<prompt> All of the following are associated with Down syndrome except: March 2010Sensory hearing lossVSDHypothyroidismDuodenal atresia  <response>: Ans. A: Sensory Hearing Loss Around 40 percent of children are born with a congenital hea abnormality, most commonly a atrio or ventricular septal defect. Underactive thyroid problems, diabetes and problems with the intestinal and digestive tract are also seen in people with Downs syndrome, especially duodenal atresia. Patient may have conductive hearing loss. Most children with Downs syndrome experience respiratory tract problems, due to the small nasal bridge and the shoer lung capacity. There is some evidence to suggest that people with Downs syndrome have an increased probability of developing Alzheimers disease. People with Downs syndrome have a characteristic facial appearance. For example, Their eyes appear to slant upwards and outwards. The head is usually flatter at the back and people with Downs syndrome often have a low hairline. The face often appears flatter with a flat nasal bridge and the tongue is often larger than usual. Iv.The ears often appear small and low set and there is often a distinctive fold of loose skin on the back of the neck. This increased thickness on the back of the neck may be detected in pregnancy nuchal translucency and can contribute to a diagnosis of Downs syndrome. People with Downs syndrome often have broad hands with sho fingers. Other common features associated with Downs syndrome include floppiness or poor muscle tone hypotonia, and loose or bendy joints. For this reason, children are often slower to achieve their physical milestones such as sitting up and walking. They may also have difficulty feeding. 