<prompt> Which of the following is the most likely inheritance pattern in the pedigree given below-Autosomal dominantMitochondrialAutosomal recessiveX-linked dominant  <response>: It is an X-linked dominant pattern of inheritance.The features which suggest the X-linked dominant pattern of inheritance are-A single abnormal X chromosome is sufficient to express the disease.All of the female offsprings of a diseased male XY will receive the abnormal X chromosome and express the disease, whereas none of the male offspring to the diseased father will have the disease as sons dont receive X chromosome from their father.A diseased mother can transmit the abnormal X chromosome to both daughter and sons equally.Important facts If a female is transmitting the disease to all offsprings both males and females and a male is not transmitting the disease to any child, it is mitochondrial inheritance.If a male is transmitting the disease only to daughters all daughters and not to the sons whereas female transmit the disease to half daughters and half of the sons, it is X-linked dominant.If only males are affected in a pedigree, it is likely to be an X-linked recessive disease females act as carriers; only transmit the disease and themselves remain unaffected.If there is no sex-predilection and affected individuals transmit the disease to half of the offsprings, it is an autosomal dominant disorder.If there is no sex-predilection and affected individuals transmit the disease to one-fourth of the offsprings, it is likely to be an autosomal recessive disorder. 