<prompt> Li-Fraumeni syndrome has the risk of development of:Squamous cell carcinomaBasal cell carcinomaOsteosarcomaBoth 1 3  <response>: Li-Fraumeni syndrome germline TP53 mutation is a predisposing factor for osteosarcoma development.Reference: Shafers Textbook of ORAL PATHOLOGY Eighth Edition page no 227 