<prompt> Secondary syphilis is characterized by the following except -Occurs 6-8 weeks after development of chancrePainful and itchy maculopapular lesionsConstitutional features are presentMeningitis, hepatitis, glomerulonephritis and uveitis may occur  <response>: The protean manifestations of the secondary stage usually include mucocutaneous lesions and generalized nontender lymphadenopathy. The skin rash consists of macular, papular, papulosquamous, and occasionally pustular syphilides; often more than one form is present simultaneously. The eruption may be very subtle, and 25 of patients with a discernible rash may be unaware that they have dermatologic manifestations. Involvement of the hair follicles may result in patchy alopecia of the scalp hair, eyebrows, or beard in up to 5 of cases. Constitutional symptoms that may accompany or precede secondary syphilis include sore throat 15-30, fever 5-8, weight loss 2-20, malaise 25, anorexia 2-10, headache 10, and meningismus 5. Acute meningitis occurs in only 1-2 of cases. Less common complications of secondary syphilis include hepatitis, nephropathy, gastrointestinal involvement hyperophic gastritis, patchy proctitis, or a rectosigmoid mass, ahritis, and periostitis. Harrisons Principles of internal medicine, 20th edition, page 1382 