<prompt> All of the following define severe ARDS according to the berlin Definition of ARDS?paO2FiO2 200Acute Onset 1 weekBilateral Alveolar opacitiesNon-Cardiogenic Pulmonary edema  <response>: ARDS according to the Berlin Definition is defined as ;Severe ARDS; when PaO2FiO2 is 100 mmHg on ventilators setting that include PEEP 5cm H2O. The Berlin definition of ARDS: The Berlin definition of ARDS-2012 aims to replace the American-European consensus conference;s definition of ARDS-1994. The major changes to the Berlin Definition are that The term Acute Lung Injury Or ;ALI; has been eliminated The Pulmonary capillary wedge pressure criterion has been removed Minimal ventilator settings have been added ARDS Berlin definition of acute respiratory distress syndrome: Timing: Within 1 week of known clinical insult or new or worsening respiratory symptoms Chest imaging: Bilateral opacities- not fully explained by effusions, lobarlung collapse, or nodules Origin of edema: Respiratory failure not fully explained by cardiac failure or fluid overload. Need objective assessment to exclude hydrostatic edema if no risk factor is present Oxygenation: Mild: 200mmHg PaO2FiO2 300 mmHg with PEEP or CPAP 5cm H2O Moderate: 100mmHg PaO2FiO2 200 mmHg with PEEP 5cmH2O Severe: PaO2FiO2 100 mmHg with PEEP 5 cm H2O Ref: Harrisons 20th edition 