<prompt> A 35 years old female presented with acne. She was treated for her acne but after the treatment, she developed pigmentation. Which drug is responsible for hyperpigmentation?TetracyclineErythromycinMinocyclineDoxycycline  <response>: Minocycline Oral antibiotics - most widely prescribed agents in acne Dose -100-200 mg daily Indicated for severe acne, moderate facial acne not responding to topical therapies andor extensive truncal acne. Adverse effects with minocycline include drug hypersensitivity syndrome DHS - within 3 months of treatment initiation characterized by fever, malaise, ahralgia and a diffuse exanthematous skin eruption. lupus?like reaction Hyperpigmentation of skin nails Melanonychia dark nails 