<prompt> Moderate to high titres of anti-DNA and anti-Smith antibodies are almost pathognomonic of:SLEEMLichen planusAll of the above  <response>: Laboratory FindingsAntinuclear antibodies are frequently found in patients with SLE and can be used to indicate a systemic involvement, but patients with other rheumatologic diseases, such as Sjögrens syndrome and rheumatoid arthritis, may be positive as well. Moderate to high titers of anti-DNA and anti-Smith antibodies are almost pathognomonic of SLE. 