<prompt> All of the following changes are seen in dysplasia of squamocolumnar junction, except:Breaking of basement membraneChange of epitheliumHyperchromatic nucleiIncreased mitotic figure  <response>: Ans. is a, i.e. Breaking of basement membraneRef: Robbins 7thed, pl076, Shaw 15thed, p400Dysplasia: Represents a change in which there is alteration in cell morphology and disorderly arrangement of the cells of the stratified squamous epithelium. It is a premalignant lesion.Characteristics of Dysplastic cell: Vary in sizeQ, shapeQ and polarityQ. Have altered nucleo-cytoplasmic ratio NC ratio is increased.Q Have large, irregular hyperchromatic nuclei with marginal condensation of chromatin material.Q Have several mitotic figures. The basement membrane, however, is intact and there is no stromal infiltration. 