<prompt> Biguanides acts by following except -Insulin release from pancreasGlycolysisGluconeogenesisInsulin binding to its receptors  <response>: Ans. is a i.e., insulin release from pancreash Biguanides acts by : o Suppress hepatic gluconeogenesis and glucose output from liver major action. o Enhance insulin mediated glucose disposal in muscle and fat Increased peripheral utilization of glucose by enhancing GLUT-I transpo from intracellular site to plasma membrane. o Retad intestinal absorption of glucose. o Promote peripheral glucose utilization by enhancing anaerobic glycolysis. 