<prompt> Which of the following is not a prokinetic?5HT4 agonistD2 blockerMacrolidesDiphenoxymethane  <response>: Prokinetic drugs. - These are drugs which promote gastrointestinal transit and speed gastric emptying by propulsive motility.D2blocker example Domperidone. 5HT4 agonistexample cisapride. Metoclopramide. Macrolidesacts on motilin receptor. Hence, Diphenoxymethane is the answer. 