<prompt> In apoptosis, Apaf-1 is activated by release of which of the following substances from the mitochondria ?Bel - 2BaxBcl - XLCytochrome C  <response>: Ans is d i.e., Cytochrome CApoptosis is induced by a cascade of molecular events all of which culminate in the activation of caspases. In the cytosol cytochrome C binds to a protein called Apaf I Apoptosis activating factor - 1 and the complex activates caspase 9 