<prompt> Pap smear of Lelawati 45-years female shows CIN grade III. Which of the following is the next step in management:Punch biopsyLarge loop excisionColposcopy directed biopsyCone biopsy  <response>: Ans. is c, i.e. Colposcopy directed biopsyRef: CGDT 10thed, p837, 841; Harrison 17thed, p608; Williams Gynecology 1sted, p628, Table 29-6 William Gynae 3rded, p629 