<prompt> In a case of ectopic pregnancy, medical treatment is contraindicated if:Sac size is 3.0 cmSerum HCG levels 1500 miu mlSignificant hemoperitoneum is presentAbsent fetal activity  <response>: Criteria for medical treatment 1 Ectopic mass 3.5cm the presence of fetal cardiac activity is a contra-indication to medical treatment2 No fetal cardiac activity3 Initial hCG 3000iul4 The patient must be hemodynamically stable, with no signs or symptoms of active bleeding or hemoperitoneum.5 She should not have any contraindications to the use of methotrexate. 