<prompt> In which of the following disorders, administration of barbiturates is contraindicatedAnxiety disordersAcute intermittent porphyriaKernicterusRefractory status epilepticus  <response>: Barbiturates induce the rate-limiting enzyme δ-amino clavulanic acid synthase in porphyrin synthesis. This increased synthesis of porphyrins can precipitate an acute attack of AIP. 