<prompt> Which of the following cytokine have endogenous pyrogenic activity?IL-8IL-6TGF-bIL-3  <response>: Cytokine functions IL-3 Multi-CSFinduce growth of all type of hematopoietic cells in soft agar IL-6 Endogenous pyrogenic activity Promote B-cell differentiation IgG production IL-8 Neutrophil chemotactic factor TNF-beta Induce other cytokines IL-1 and TNF -alpha are also responsible for pyrogenic avtivity. 