<prompt> Metachromatic leukodystrophy is due to deficiency ofHexosaminidase AHexosaminidase BCeramidaseArylsulfatase  <response>: DiseaseEnzyme deficiencySymptomsMetachromaticleukodystrophyArylsulfatase AMental retardation and psychologic disturbances in adults; demyelinationRef: Harper;s Biochemistry; 30th edition; Chapter 24 Metabolism of Acylglycerols Sphingolipids 