<prompt> Progressive transformation of germinal centres is a precursor lesion of:Hodgkins lymphoma ,nodular sclerosisHodgkins lymphoma,mixed cellularityAnaplastic large cell lymphomaPeripheral T cell lymphoma  <response>: Progressive transformation of germinal centres is a beningn reaction pattern in lymphnodes.it is most often associated with reactive follicular hyperplasia. It is also associated with nodular sclerosis and lymphocyte predominant Hodgkins lymphoma. ref Loachims lymphnode pathology 186 