<prompt> All of the following are true regarding minimal change glomerulonephritis except: March 2005Poor response to steroidsNormal glomerulusMore common in childrens than adultsAbsence of podocytes  <response>: Ans. A: Poor response to steroids This form of GN causes 80 of nephrotic syndrome in children, but only 20 in adults. As the name indicates, there are no glomerular changes visible on simple light microscopy, but on electron microscopy there is fusion of podocytes suppoive cells in the glomerulus. Treatment consists of suppoive care for the massive fluid accumulation in the patients body and as well as steroids to halt the disease process. Over 90 of children respond well to steroids, being essentially cured after 3 months of treatment. Adults have a lower response rate 80. Failure to respond to steroids steroid resistant or return of the disease when steroids are stopped steroid dependent may require cytotoxic therapy such as cyclosporin. 