<prompt> Which of the following drug reduces blood pressure by directly decreasing the hea rate:PropanololPrazosinAlpha methyl dopaNitroprusside sodium  <response>: Propranolol is a non-selective beta blocker. It has a negative chronotropic effect decreases hea rate It decreases hea rate by blocking the beta1 receptors located on the hea. It also decreases renin production from JG cells of kidney decreasing BP Ref- Essentials of medical pharmacology K D TRIPATHI 8th Edition 