<prompt> Pvridoxine should be given when treating with -IsoniazidRifampicinPyrazinamideStreptomycin  <response>: Ans. is a i.e., Isoniazid o Peripheral neuritis associated with isoniaide probably relates to interference with pyridoxine vitamin B6.o Thus when treating a patient with isoniazid it is essential to supplement with pyridoxine to reduce chances of peripheral neuritis. 