<prompt> Granulomatous inflammatory reaction is caused by all, except:M. tuberculosisM. lepraeYersinia pestisMycoplasma  <response>: Granulomatous inflammation It is a distinctive pattern of chronic inflammatory reaction characterized by focal accumulations of activated macrophages, which often develop an epithelial-like epithelioid appearance. Tuberculosis is the prototype of the granulomatous diseases, Other granulomatous diseases:- Sarcoidosis Crohns disease Cat-scratch disease Lymphogranuloma inguinale Leprosy Brucellosis Syphilis Yersinia has also been mentioned to be associated with granulomatous inflammation. So, the answer to exclusion is Mycoplasma. 