<prompt> Retinoblastoma is associated with:Intracranial calcificationIntra orbital calcificationOptic canal wideningHydrocephalus  <response>: Ans: b Intra orbital calcification Ref: Khurana, 4th ed,p.Intra orbital calcification is a feature of endophytic retinoblastoma. Presents as multiple growths projecting into the vitreous giving rise to cottage cheese appearance.Ophthalmoscopic appearance of retinoblastoma.Endophytic growth - Well circumscribed polypoid mass into vitreousCalcification present, haemorrhage -Exophytic growth - Grows outwards, separating retina from choroidsOE exudative retinal detachment 