<prompt> Niemann-Pick disease is characterized by:Increased concentration of sphingomyelin in liverIncreased concentration of cerebrosides in liver and spleen.Increased concentration of plasminogenIncreased accumulation of glycerol in liver  <response>: Ans. A. Increased concentration of sphingomyelin in liverNiemann -pick disease is due to the absence of sphingomyelinase enzyme which leads to the accumulation of sphingolipids or sphingomyelin in liver. 