<prompt> Virus causing cervical cancer in the ectocervix -HPV16HPV17HPV11HPV19  <response>: Ans. is a i.e., HPV 16 Carcinoma cervixo The mc etiological factor associated with cancer cervix is Human Papillomavirus HPV.o HPV is epitheliotropic.o High-risk HPVInclude 16, 18, 31, 33, 35, 39. 45, 52, 56, 58, 59, 68.o Low-risk HPV associated with genital warts are subtype 6 and 11.o Almost 80 women are infected by HPV at some point in their lives.o HPV DNA detection is used along with pap smear as a screening procedure:o PCR polymerase chain reaction or Southern blot or hybrid capture technique is used for HPV DN A detection.Factors predisposing to CINCa Cervixo Human papilloma virus infection most importanto Factors increasing the risk of sexually transmitted infections :Coitus before 18 years of ageMultiple sex partnersMultiparityPoor personal hygienePoor socioeconomic statuso Smokingo Immunosuppressed individualso Women on OCP or progesterone therapy for a long time, are predisposed to adenocarcinoma of the endocervix.o In utero exposure to diethylstilbestrol DES. 