<prompt> Characteristic histopathology finding in Whipples disease is ?PAS positive macrophages and rod shaped bacilli in lamina propriaShoened thickened villi with increased crypt depthBlunting and flattening of mucosal surface and absent villiMononuclear infiltration at base of crypts  <response>: Ans. is a i.e., PAS positive macrophages and rod shaped bacilli in lamina propriaThe hallmark of Whipples disease is a small intestinal mucosa laden with distended macrophages in the lamina propria- the macrophages contain periodic acid-schiff PAS positive granules and rod shaped bacilli by electron microscopy.Three forms of Malabsorption Syndromes are often asked and the basic understanding of these is able to exclude a large number of questions. 