<prompt> Which method of Medical Termination of Pregnancy is not used in the first trimester of pregnancy?Intrauterine instillation of hypertonic salineSuction and evacuationMifepristoneMisoprostol  <response>: Ans. is a i.e., Intrauterine instillation of hypertonic saline o Following table depicts the methods of medical termination of pregnancy used in first and second trimester abortion. Intrauterine instillation of hypertonic saline is preferred in the second trimester and not the first.METHODS OF TERMINATION OF PREGNANCYFirst Trimester Up to 12 WeeksSecond Trimester 13-20 WeeksMedicalo Mifepristoneo Mifepristone and misoprostol PGE,o Methotrexate and misoprostolo Tamoxifen and misoprostolSurgicalo Menstrual regulation see p.646o Vacuum aspiration MVAEVA see p.646o Suction evacuation andor curettageo Dilatation and evacuation : Rapid method Slow methodo Prostaglandins PGE2 misoprostol, 15 methyl PGF2 a Carboprost, PGE, Dinoprostone and their analogs used-intravaginally, intramuscularly or intraamnioticallyo Dilation and evacuation 13-14 weekso Intrauterline Instillation of hyperosmotic solutions Extra-amniotic-ethacridine lactate, Prostaglandins PGE,, PGE2 a Extra-amniotic saline infusion isotonic with a transcervical catheter balloon Intra-amniotic hypertonic urea 30, saline 20o Oxytocin infusion - high dose used along with either of the above two methodso Hysterotomy abdominal - less commonly done 