<prompt> Which of the following layers of epidermis is known as prickle layer?Stratum basaleStratum spinosumStratum granulosumStratum corneum  <response>: Ans. B. Stratum spinosumStratum spinosum is also called as the prickle cell layer. Stratum spinosum consists of intercellular attachments, also called desmosomes. These desmosomes appear like spines on microscopy; hence, it is called as the prickle layer. Their spiny Latin, spinosum appearance is due to the shrinking of the microfilaments between desmosomes that occurs when stained with HE. 