<prompt> A 20-year-old patient weighing 60 kg has to be prescribed an antiepileptic drug availableas 200 and 400 mg tablets for generalized tonic-clonic seizures. The pharmacokinetic parametersand therapeutic plasma concentration of the selected drug are:Target steady-state plasma concentration Cpss 6 mgLOral bioavailability F 70Volume of distribution V 1.4 LkgClearance CL 80 mlhrkgPlasma half life t12 15 hoursWhat should be the loading dose and the daily maintenance dose of the drug for this patient?720 and 984 mg respectively984 and 720 mg respectively450 and 720 mg respectively884 and 984 mg respectively  <response>: The total volume of distribution and total body clearance for this patients has to be calculated first. 