<prompt> Bad prognostic indicator of Schizophrenia isLate onsetFamily history of SchizophreniaPositive precipitating factorsProminent affective symptoms  <response>: B i.e. Family history of schizophreniaPrognostic Factors: Predictors of Course Outcome in SchizophreniaFactorsGood outcomei.e. Better prognosisPoor OutcomePoorer prognosisOnsetAge at onset clinicalOnset type of SchizophreniaAcute abruptQAbout 20-25Late onset Schizophrenia 45 yrQInsidiousQBelow Early childhood onsetSchizophreniaQRate of progression clinicalEpisode of schizophreniaLength of episode prior to assessment i.e.CourseRapidFirstSho months or less; 6monthsSlowPast history of schizophreniapresentChronic years; 2yearsSex PhysiqueFemaleQ, Fatty pyknicQMale, Thin asthenicQFamily history of mental illnessAffective mood disorder2SchizophreniaPrenatal adverse events other adversesocial factorsGene polymorphism eg COMT catechol-0-methyl-transferase, NMDA2A,NRG1 neuregulin, DTNBP1 dysbindin,G72, DAAO D-aminoacid oxidase,RGS4, PRODH Proline dehydrogenaseGenetic factors absentnoneGenetic factorsPresentPrecipitating factor stressorPresentAbsentInitial Clinical SymptomsMood disorder symptomsespecially depressionQ,Withdrawnnegative symptomseg flat or blunt affect, povey of predominance of positivesymptoms, catatonia, paranoia,schizoaffective symptoms, atypicalsymptoms, confusiondisorientationperplexitythought, apathy, asociality;obsessive-compulsive symptoms,autistic behaviorSchizophrenia-subtypeCatatonia subtype paranoid hasintermediate prognosis, type 1non-deficit typeDisorganized, simple,undifferentiated, chronic catatonic,type II deficit typeCTMRI HeadNormal morphologyDilated enlarged ventricle, brainatroph y2Neurological signs symptoms; HOperinatal trauma; assaultiveness, substanceabuse, cannabis use, many relapses noremission in 3 yearsAbsentPresentPremorbid scocial, sexual, and workGood eg married, resident ofPoor eg single, divorced;occupational historiesdeveloped country, middle or highwidowed; underdeveloped socioeconomic statusnation, low S-E status, irregularoccupational recordEarly treatment with medication, long termPresentAbsent i.e. absence of properdrug maintenance, response to medication treatment or poor response toinitially; out door treatment treatment or required long termhospitalization 