<prompt> Which among the following drug is used in benign prostatic hyperplasia?FlutamideTamsulosinDuloxetineSolifenacin  <response>: Ans: b Tamsulosin Ref: KDT, 6 ed, p. 135Tamsulosin:Uroselective alpha 1A blocker alpha 1A: alpha 1B 1:7-38 fold for BPH.No significant change in HR BP: postural hypotension.AE: Retrograde ejaculation, dizziness.Flutamide:Competitive blocker of androgen receptor.Use: Palliative role in prostate cancer along with GnRH agonism.AE: Gynaecomastia. breast tenderness.Finasteride:5 alpha reductase Type 2 inhibitor in male urogenital tract.Results in decreased prostatic size increased peak urinary flow rate in about 50 patients with symptomatic benign hypertrophy of prostate.6 months treatment needed for maximum relief.AE: Decreased libido, impotence, decreased ejaculate volume. 