<prompt> The characteristic lesion of atherosclerosis isFibrinoid necrosis of the mediaGiant cell reaction in the retina and internal elastic laminaOrganised thrombus in the affected segmentFibro-fatty lesion in the intima of the blood vessels  <response>: Atherosclerosis is a intima based lesion composed of a fibrous cap and an atheromatous core: the constituents of the plaque include smooth muscle cells, ECMs, inflammatory cells, lipids and necrotic debris Robbins 9th edition page no 343 