<prompt> Drug of choice for obsessive-compulsive disorderBuspironeHaloperidolFluoxetineOlanzapine  <response>: C Fluoxetine Drug Treatment: Benzodiazepines e.g. Alprazolam, Clonazepam have a limited role in controlling anxiety as adjuncts.Antidepressants: Some patients may improve dramatically with specific serotonin reuptake inhibitors SSRIs. Clomipramine 75-300 mgday, a non specific serotonin reuptake inhibitor SRI, is the first drug used effectively in the treatment of OCD. The response is better in presence of depression, but many patients with pure OCD also improve substantially. Fluoxetine 20-80 mgday is a good alternative to clomipramine. Fluvoxamine 50-200 mgday is marketed as a specific anti-obsessional drug, while paroxetine 20-40 mgday, and sertraline 50-200 mgday are also effective in some patients. Antipsychotics: These are occasionally used in low doses e.g. haloperidol, risperidone, olanzapine, pimozide in the treatment of severe, disabling anxiety. Buspirone has also been used beneficially as an adjunct for augmentation in some patients. 