<prompt> Prion disease is caused byMisfolding of proteinDenaturation of ProteinReduced formation of proteinExcess formation of protein  <response>: ref Robbins 9e p1281 Prion diseases are caused by misfolded forms of the prion protein, also known as PrP. ... The human forms of prion disease are most often the names Creutzfeldt-Jakob disease CJD, fatal familial insomnia FFI, Gesmann-Straussler-Scheinker syndrome GSS, kuru and variably protease-sensitive prionopathy VPSPr 