<prompt> Carpal tunnel syndrome is due to compression of:Median nerveAnterior internsseus nerveRadial nerveUlnar nerve  <response>: Ref: Wheel ess Textbook of Orthopaedics Apleys System of Orthopaedics and Fractures, 8th ed.Explanation:Carpal Tunnel SyndromeMedian nerve compression syndrome at the wrist;Most common form of nerve entrapmentPathophysiology: Nerve compression may result in:IschemiaFocal demy el i nationDecrease in axonal caliberAxonal lossPresence of pain in the wrist andor fingers and presence of paresthesias in fingersNight pain may be especially predictiveMRI: Indicated when atypical CTS due to tumor or anomalous muscle is suspectedNon Operative Treatment: Carpal tunnel injection Median nerve blockSurgical Treatment: Goals of surgery:Eliminate compression by the tenosynovium;Tenosynovectomy is performed if tissue is bulky, displaces flexor tendonsRestore the gliding capacity of the nerveRemove constriction by external epineurium, liberate fascicles from internalReleaseSurgical Treatment Options:Open surgical release- Endoscopic carpal tunnel release 