<prompt> 5-Lipo - oxygenase synthesis inhibitor isZileutonZafirleucastMonteleucastOmalizumab  <response>: Zileuton 175, 223-KDT 6thZILEUTON -- is a 5 LOX inhibitor blocks LTC4D4 as well as LT B4 synthesis, clinical efficacy in asthma similar to montelucast. The duration of action is short with hepatotoxic potential. These limitations have restricted to useLEUKQTRIENE ANTAGONIST Montelukast, Zafirlukast are indicated for prophylactic therapy of mild to moderate asthma as alternatives to inhaled glucocorticoids, churg- strauss syndrome is an important complications.OMALIZUMAB - Anti-IgE antibody - is a recombinant DNA derived monoclonal antibody that selectively binds to human immunoglobulin E IgE uses - Moderate to severe allergic asthmaCORTICOSTEROIDSA. Systemic:- Hydrocortisone, Prednisolone and othersB. Inhalational - Beclomethasone, dipropionate, Budesoride,fluticasone.propionate, Flunislide, Ciclesonide Nodocromil is mast cell stabilizer Loading dose of Aminophylline is - 5-6 mgkg Long acting beta-2 b2 agonist is - Salmetarol Albuterol - selective b2 receptor agonist Letrozole is an aromatase inhibitor 