<prompt> The differences between the liver and muscle in the glucose utilization from blood are due to the different regulatory propeies of:HexokinasePyruvate kinasePhosphoglucomutaseAldolase  <response>: Glucokinase is an isozyme of hexokinase in the liver. It has a different affinity to glucose and different regulatory propeies. Muscle hexokinase is inhibited by its product, glucose-6-phosphate, while glucokinase in the liver is inhibited by fructose-6-phosphate. In the last case, the inhibition involves an additional regulator protein. Fructose-1-phosphate direct product of the phosphorylation of fructose can replace fructose-6-phosphate competitively and thus block its inhibitive influence. This explains why high levels of fructose in the blood stimulate glucose uptake by the liver. Ref: Bender D.A., Mayes P.A. 2011. Chapter 20. Gluconeogenesis the Control of Blood Glucose. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell Eds, Harpers Illustrated Biochemistry, 29e. 