<prompt> In a case controlled study. It is found that the disease is more common in the group taking coffee as compared to the control group. The significance of this is-Cause and effect relationship establishedDisease median can be calculatedCaffeine is associated with occurrence of diseaseControls will not get the disease  <response>: Case-control studies basically comparison study. Cases and control must be comparable with respect to known confounding factor such as age , sex occupation, social status, etc. The questions asked relate to personal characteristics and antecedent exposures which may be responsible for the condition studied. 