<prompt> An increase in which of the following parameters will shift the O2 dissociation curve to the left -Increased temperatureIncreased partial pressure of CO2Increased 2, 3 DPG concentrationIncreased oxygen affinity of hemoglobin  <response>: Hb-O2 dissociation curve shift to left indicates more affinity of Hb to O2 and thus less delivery of O2 to tissues.Shift to left seen in- Increased pH- Decreased 2,3 DPG, temperature, PCO2- HbF FetalShift to right seen in- Decreased pH- Increased 2,3DPG, temperature, PCO2- HbS Sickle cell 