<prompt> A male neonate is born with an omphalocele. This entity can be distinguished from gastroschisis, because in an omphalocele, the protrusion is:Not covered by a sacA defect in the abdominal musculatureAssociated with Intestinal atresiaAssociated with congenital malformations  <response>: Abdominal wall defects Omphalocele- Intestine fails return to the intra-abdominal cavity- Covered by 2 layers Amnion Peritoneum- For Small defect - Protrusion of small amounts of bowel- For Large defect - Protrusion of small bowel along with liver- Associated with Trisomy 13, 18, 21- Associated with congenital malformations - CVS Musculoskeletal system Gastrointestinal system Genito urinary system- MC cause of death - congenital malformations- Associated with BECKWITH - WEIDMAN SYNDROME variant of Wilms tumour Hemi hyperophy Macroglossia Visceromegaly Omphalocele Hepatoblastoma- Poor prognosis associated with congenital malformations Gastroschisis- Splitting of abdominal wall from right side with herniation of bowel.- Bowel is exposed, not covered and becomes thickened,matted and edematous- Associated with Intestinal atresiaRisk factors- If mother has history of intake of Alcohol Smoking Aspirin during first trimester Ibuprofen Pseudoephedrine- Age of mother - 20 years age- Not associated with congenital anomalies - so good prognosis 