<prompt> Which toxin of streptococcus causes hemolysis around colonies:Streptolysin OStreptolysin SStreptodornanseHyaluronidase  <response>: Option 1, 2 Streptolysin O Streptolysin S Oxygen labile Oxygen stable Hemolysis in reduced state only Hemolysis around streptococcal colonies. Cannot cause hemolysis on the surface of blood agar. Option 3 DNase DeoxyribonucleaseStreptodornanse : Diagnostic use: Anti-DNase B 300-350 U is useful for the retrospective diagnosis of skin infections pyoderma and acute glomerulonephritis where ASO titer is low. Option 4 Hyaluronidase spreading factor: Expressed by non-capsulated strains, such as M type 4 and 22. 