<prompt> Which of the following is a clinical feature of rickets ?Early closure of anterior fontanelleCraniotabesPseudoparalysis of the lower extremitiesDecrease in upper segment to lower segment ratio  <response>: Clinical manifestations of rickets include skeletal deformities like bow legsgenu varum in toddlers,knock- kneesgenu valgum in older children,craniotabessoft skull,costichondral swellingrickety rosary,Harrison groove,double malleoli due to metaphyseal hyperplasia,increased tendency for fractures,especially greenstick fractures,etc. Reference: GHAI Essential pediatrics, 8th edition 