<prompt> Following can reduce the glomerular filtration rate GFR EXCEPTNorepinephrineEpinephrineEndothelium derived nitrous oxide EDRFEndothelin  <response>: Ans. c. Endothelium derived nitrous oxide EDRF Ref. Guyton physiology 11th320; 322; Table 26-4Hormones and Autacoids That Influence Glomerular Filtration Rate GFRHormone or AutacoidEffect on GFRNorepinephrineEpinephrineEndothelinAngiotensin IIprevents -Endothelial-derived nitric oxideProstaglandinsFACTORS THAT CAN DECREASE THE GLOMERULAR FILTRATION RATE GFRPhysical DeterminantsPhysiologicPathophysiologic CausesKf glomerular filtration coefficient GFRRenal disease, diabetes mellitus, hypertension PB Bowmans capsule hydrostatic pressure GFRUrinary tract obstruction e.g., kidney stonespG glomerular capillary colloid osmotic pressure GFRPG glomerular capillary hydrostatic pressure GFR Renal blood flow, plasma proteinsAP PG Arterial pressure has only small effect due to autoregulation- RE PG Angiotensin II drugs that block angiotensin II formation RA -PG Sympathetic activity, vasoconstrictor hormones e.g., norepinephrine, endothelin 