<prompt> In hypogonadotropic hypogonadism?Both LH and FSH decreasedBoth LH and FSH increasedLH increased and FSH decreasedLH decreased and FSH increased  <response>: - LH and FSH are decreased in hypogonadotropic hypogonadism. Hypogonadotropic hypogonadism: - Reversible - if its dt to Chronic systemic illness CKD, Chronic liver Disease Severe malnutrition Endocrine causes hypothyroidism, type 1 DM - Permanent if its dt Isolated delayed pubey - Genetic mutations - KAL 1 Kallmann Syndrome, GnRH Receptor, DAX -1 gene - Syndromes- Prader Willi Syndrome, Laurence Moon Syndrome MPHD multiple pituitary hormone disease - Injury - Infiltration by tumors- Langerhan cell histiocytosis - Genetic - PROP1,LH - Malformations - Trauma 