<prompt> A patient with eruptive xanthomas, drawn blood milky in appearance. Which lipoprotein is elevated in the plasma?ChylomicronChylomicron remnantsLDLHDL  <response>: Ans. A. ChylomicronRef: Harrison 19e Chapter Disorders Associated with Metabolism of LipoproteinsThis is a case of Type I hyperlipoproteinemia familial chylomicronemia syndromeFamilial Chylomicronemia Syndrome Type I Hyper-lipoproteinemiaBiochemical abnormalitiesLipoprotein Lipase LPL or Apo-CII defect.Lipoprotein accumulated is chylomicron and VLDL, but chylomicron predominates.Fasting triglycerides is 1000mgdLFasting cholesterol is elevated to a lesser degree.Clinical presentationPresent in childhood with recurrent abdominal pain due to acute pancreatitisOn fundoscopic examination opalescent retinal blood vessels lipemia retinalisLactescent plasmaQEruptive xanthoma small yellowish white papules appear in clusters on backs, buttocks, extensor surfaces of arms and legs. These are painless skin lesions may become pruriticHepatosplenomegalyPremature CHD is not a feature of FCS. 