<prompt> On acclimatizing to new height, our body maintains the body pH byRetaining HCO3Excretion of HCO3 by kidneyProducing more Hb which is a bufferIncreasing 2,3-DPG  <response>: Ans: d Increasing 2,3-DPG Ref: Ganong 22nd ed p.686AcclimatizationAn acclimatized person is one who has developed compensatory mechanisms, so that hypoxia causes less adverse effects on the body.Compensatory mechanisms in acclimatization:-Ventilatorv response:-The initial ventilatory response is small as alkalosis tends to counteract effect of hypoxia. However, ventilation increases over the next 4 days. After 4 days, ventilatory response begins to decline slowly.The respiratory alkalosis produced by hyperventilation shifts O2-Hb dissociation curve to the left, but a concomitant increase in 2,3- DPG tends to decrease the O2 affinity of haemoglobin.Bloodresponse:-Erythropoetin secretion increases and then falls after 4 days.The increase in RBC begins in 2-3 days polycythemia Compensatory changes in tissue:-Mitochondria increases in number.Myoglobin increases.Cytochrome oxidase content increases. 