<prompt> Which of the following is secreted by beta cells of pancreas along with insulin?SomatostatinAmylinPancreatic polypeptideGlucose like peptide  <response>: Ans. b. Amylin Ref: Katzung 12ep763; Ganong 23e p316;Guyton 12e p939; Sabiston 19e p946 Amylin is produced by pancreatic beta cells, packaged within beta-cell granules in a concentration 1-2 that of insulin and co-secreted with insulin in a pulsatile manner and in response to physiologic secretory stimuliAmylin is a 37-amino-acid peptide originally derived from islet amyloid deposits in pancreas material from patients with long-standing type 2 diabetes or insulinomas. It is produced by pancreatic beta cells, packaged within beta-cell granules in a concentration 1-2 that of insulin and co-secreted with insulin in a pulsatile manner and in response to physiologic secretory stimuli. The physiologic effect of amylin may be to modulate insulin release by acting as a negative feedback on insulin secretion. At pharmacologic doses, amylin reduces glucagon secretion, slows gastric emptying by a vagally medicated mechanism, and centrally decreases appetite. --Katzung 12e p763Islet CellsContentAlpha cellsGlucagon, pancreastatinQ, glicentinQ PGBeta cellsInsulin, amylinQ pancreastatinQ IAPD celtsSomatostatinD2 cellsVIPG cellsGastrinPP cellsPancreatic polypeptide 