<prompt> On follow up study, elevated CA 125 in a case of epithelial ovarian tumor should be further evaluated with?MRICT ScanYearly follow upClinical examination and serial CA 125 monitoring  <response>: Ans. B. CT Scana. Evaluation of patients with suspected ovarian cancer should include measurement of serum levels of the tumor marker CA-125.b. CA-125 determinants are glycoproteins with molecular masses from 220to1000kDa, and a radioimmunoassay is used to determine circulating CA-125 antigen levels. Between 80 and 85 of patients with epithelial ovarian cancer have levels of CA-125_35UmL.c. Other malignant tumors can also elevate CA-125 levels, including cancers of the endometrium, cervix, fallopian tubes, pancreas, breast, lung, and colon.d. Certain nonmalignant conditions that can produce moderate elevations of CA-125 levels include pregnancy, endometriosis, pelvic inflammatory disease, and uterine fibroids. About 1 of normal females have serum CA-125levels_35UmL. 