<prompt> Non hormonal drug to prevent post menopausal osteoporosis is:AlendronateEstrogenRaloxifeneParathyroid  <response>: Alenderonate, etidronate, pamidronate, and Ibandronate are bisphosphonates which inhibit bone resorption, and are very effective for both osteoporosis prevention and treatment.Uses: First line drugs for treating postmenopausal osteoporosis Pagets disease Osteolytic bone metastasis.Caution: Patient should be instructed to take these drugs on an empty stomach with a large glass of water and then to remain upright for atleast 30 minutes as its major side effect is GI upset.Route of administration: Oral or IV infusionNow lets have a look at other options: Raloxifene: It is a selective estrogen receptor modulator which is also useful in management of osteoporosis but it is a hormonal preparation. Parathyroid hormone: It is a novel therapy for osteoporosis. Unlike most of the treatments for osteoporosis that inhibit bone resorption, parathyroid hormone stimulates new bone formation. It is given by daily subcutaneous injection.Also Know:Other non-hormonal drugs used for treatment of osteoporosis:a. Calciumb. Vitamin Dc. Calcitonind. Slow releasing sodium fluoride. 