<prompt> A ten-year old girl presents with swelling of one knee joint. All of the following conditions can be considered in the differential diagnosis, EXCEPT:TuberculosisJuvenile rheumatoid ahritisHaemophiliaVillonodular synovitis  <response>: Hemophilia is an X-linked recessive hemorrhagic disease due to mutation in the F8 gene Hemophilia A or Classic Hemophilia or F9 gene Hemophilia B. Males subjects are clinically affected; women who carry single mutated gene are generally asymptomatic. Ref: Kliegman, Behrman, Jenson, Stanton 2008, Chapter 476, Hereditary Clotting Factor Deficiencies, In the book, NELSON TEXTBOOK OF PEDIATRICS, Volume 2, 18th Edition, New Delhi, Page 2066; Harrisons Internal Medicine, 19th Edition, Page 975. 