<prompt> Which concept was put forth by Pettenkofer in 1819-1901Ecological conceptHolistic conceptMultifactorial causationBiomedical Concept  <response>: Multifactorial CausationThis concept was put forth by Pettenkofer of Munich 1819-1901. Modern diseases of civilization like coronary heart disease and cancers could not be explained on the basis of the single cause idea, because they were due to multiple factors. This concept offers multiple approaches for the prevention of disease. 