<prompt> Sign of chronic inflammation -AngiogenesisPurulent exudateIndurationEdema  <response>: Ans. is a i.e. Angiogenesis Chronic inflammation is characterized byo Infiltration with mononuclear cells, which include - macrophages, lymphocytes, and plasma cellso Tissue destruction, induced - the persistent offending agent or by the inflammatory cellso Attempts at healing - connective tissue replacement of damaged tissue, accomplished by angiogenesis proliferation of small blood vessels and, in particular, fibrosis. 