<prompt> Acute graft versus host disease reaction occurs in all EXCEPTLiverAdrenalGutSkin  <response>: Adrenal 125 - R 134- Basic pathology 8th Two major problems complicate this form of transplantation bone marrow transplant rejection and graft versus host disease GVHD Acute graft versus host disease occurring due to weeks after transplant causes epithelial necrosis in three principal target organs - liver, gut and skin 