<prompt> All statement about PlummerVinson syndrome are true except -Commonly leads to carcinoma in lower third of esophagusCommon with iron deficiencyCommon in femalesPremalignant  <response>: Plummer-Vinson syndromePlummer-Vinson syndrome, also known as Brown-Kelly-Paterson syndrome or sideropenic dysphagia, seen in middle-aged edentulous women.The plummer Vision Paterson Brown-Kelly Syndrome is characterized by : -DysphagiaChronic iron deficiency anaemiaAtrophic oral mucosa and glossitisBrittle, spoon-shaped fingernails KoilonychiaThe cause of dysphagia is usually a cervical esophageal web, but abnormal pharyngeal and esophageal motility may play a role.The syndrome characteristically occurs in middle-aged edentulous without teeth women.It is a premalignant lesion. Approximately 10 of patient develop squamous cell Ca of esophagus, oral cavity or the hypopharynx.As iron-deficiency anemia is a common finding, it is also known as sideropenic dysphagia.Carcinoma develops in the postcricoid region not in the lower third oesophagus. 