<prompt> All statement about Plummer Winson syndrome are true exceptCommonly leads to carcinoma in lower third of oesophagusCommon with iron deficiencyCommon in femalesPremalignant  <response>: Plummer Winson syndrome Classical Features: Dyspahgia Iron Deficiency Anaemia Glossitis Angular Stomatitis Koilonychia Achlorhydria Atrophy of mucous membrane of a the alimentary canal. Predominantly affects females past 40 years Predisposes to development of carcinoma in - Tongue, Buccal mucosa, Pharynx, Esophagus and Stomach. Ref: Textbook of diseases of ENT, PL Dhingra, 7th edition, pg no. 389 