<prompt> Mechanism of analgesia is bya Nociceptin stimulationb Nocistatin stimulationc Anandamide receptorsd Nicotinic cholinergic receptorsabcacdabdbcd  <response>: Nocistatin stimuli inhibit nociceptors and produce analgesia.Anandamide a cannabinoid produces analgesic effect by binding to CB1 receptors.Acetylcholine and nicotinic cholinergic receptors subunits α4 and β 2 are involved in regulation of pain. 