<prompt> Which of the following condition is characterized by presence pf hyaline deposits in alveolar walls?Interstitial lung diseaseAsthmaHyaline membrane diseaseChronic bronchitis  <response>: Neonates HMD Hyaline membrane disease composition:- fibrin Respiratory distress syndrome Adults ARDSAdult respiratory distress syndrome Usually caused due to damage of endothelial cells Subsequently injury to TYPE 1 and TYPE 2 pneumocytes ARDS:- Characterized by Acute shoness of breath Hypoxemia Diffuse pulmonary infiltrates Diagnosis of ARDS : onset 7 days Non cardiogenic pulmonary edema BL diffuse infiltrates on chest X-ray Pao2 60 mmHg Pao2Fio2 60mmHg Hyaline membrane disease: -Deposition of layer of hyaline proteinaceous material in peripheral airspaces of infants 200-300 Mild ARDS 100-200 Moderate ARDS 100 Severe ARDS Causes of RDS: immaturity of lungs most impoant substrate on which RDS develops Occurs in about 60 of infants born 28 wks Occurs in 30 of infants born bw 28-34 wks Fundamental defect in RDS is deficiency of pulmonary surfactant predominantly dipalmitoyl phosphatidyl choline smaller amounts of phosphatidyl glycerol Interstitial lung disease: Predominant involvement of interstitium progressing to fibrosis IOC: HRCT chest Radiological pattern: Reticular pattern CT chest: mild lazy ness Ka ground glass opacity 