<prompt> The following karyotype is suggestive of which disorder?Patau syndromeEdwards syndromeAlagile syndromeWilliams syndrome  <response>: The above karyotype is suggestive of patau syndrome: Trisomy 13 Clinical features of Trisomy 13Patau syndrome Cardiac defects Ventricular septal defectatrial septal defectspatent ductus aeriosus Microcephaly, Microphthalmia Cleft lippalate Developmental delay Ocular hypotelorism Holoprosencephaly Thin posterior ribs missing ribs Renal abnormalities Polydactyly with flexed fingers Polycystic kidneys Scalp defectsaplasia cutis Ref: Nelson textbook of pediatrics 21st edition pgno: 659 