<prompt> Why intravenous quinine, used in the management of complicated and severe malaria, given with 5 dextrose?To avert risk of hypoglycemiaTo avert risk of dehydrationTo avert risk of electrolyte imbalanceTo maintain renal blood flow  <response>: Ans. is a i.e., To avert risk of hypoglycemia Quinine for the management of complicated and severe malaria including cerebral malaria: Intravenous Quinine i.v. has been the drug of choice for cerebral malaria falciparum malaria with impaired consciousness and other forms of complicated malaria. Hypoglycaemia due to hyperinsulinemia is the most important side effect due to intravenous administration of quinine, which can be prevented by infusing quinine in 5 dextrose. 