<prompt> A 55 year old male presents with severe chest pain radiating to the left arm. ECG shows ST segment elevation in the V4, V5 and V6 leads. CK-MB and troponin levels are found to be increased. The most likely cause for the increase in the enzymes in serum isClumping of nuclear chromatinLysosomal AutophagyMitochondrial swellingCell membrane defects  <response>: Answer: d Cell membrane defectsREVERSIBLE IRREVERSIBLE INJURIESReversible cell injuryIrreversible cell injury Cellular swelling - first manifestation of injury Plasma membrane - blebbing, blunting, loss of microvilli Fatty change-lipid vacuoles in cytoplasm Myelin figures in cytoplasm Mitochondrial swelling and small amorphous densities Dilation of ER, detachment of polysomes Nucleus - disaggregation of granular and fibrillar elements Clumping of nuclear chromatin Cytoplasm - Myelin figures, moth eaten appearance Lysosomal swelling Plasma membrane damagedisruption Decreased basophilia, Increased Eosinophilia Marked dilation of mitochondria with large amorphous densities Nuclear changes - pyknosis, karyolysis, karyorrhexis The patient is having myocardial infarction which resulted from irreversible cardiac myocyte death. All other options are reversible injuries 