<prompt> Abnormalities of the optic lens are recognized in:HypoparathyroidismHomocystinuriaCongenital rubellaAll  <response>: A, B, C i.e. Hypoparathyroidism, Homocystinuria, Congenital rubella - Microspherophakia is usually presence of small, relatively spherical lens with increased A-P thickness and steeper A-P curvatues. It is usually bilateral and may be caused by mesodermal defect, such as Marfan syndrome, WeillMarchesani syndrome and hyperlysinaemia and congenital rubellaQ. It may be aw Peters anomaly and familial ectopia lentis et pupillae. Microspherophakia causes lenticular myopia and may lt lens dislocation usually downward and pupillary-block. - Abnormalities of central lens curvature include lenticonus conical and lentiglobus spherical, and may be anterior or posterior. It may be aw Alpos syndrome familial hemorrhagic nephritis or Lowes oculocerebral syndrome causes posterior lenticonusQ. They cause lenticular myopia with irregular astigmatism. Lens umblication is depression in the lens surface usually posteriorly. - Lens coloboma is notching dt segmental agenesis at the inferior equator with corresponding absence of zonular fibers. Cataract is seen in congenital rubella with salt pepper retinopathy, hypoparathyroidism with optic disc edema, Wilsons disease sunflower type and myotic dystrophyQ. 