<prompt> Regarding severe combined immunodeficiency disease ,which of the following statement is trueAdenosine deaminase deficiencyDecreased circulating lymphocytesNADPH oxidase deficiencyC1 esterase deficiency  <response>: Ref Robbins 8e p234;9e p239 SCID represent a constellation of genetically distinct syndrome, all having in common defect in both humoral and cell mediated immune response 