<prompt> Presence of HBeAg in serum of a patient of hepatitis-B indicates: September 2009Acute, non-infectious stageAcute, infectious stageChronic, non-infectious stageChronic, infectious stage  <response>: Ans. D: Chronic, infectious stage To detect acute hepatitis B, infection: hepatitis B, surface-antigen HBsAg, hepatitis B, core antibody anti-HBc, IgM and sometimes hepatitis B, e-antigen HBeAg To diagnose chronic HBV hepatitis: HBsAg, hepatitis B, virus HBV DNA, and sometimes HBeAg To monitor chronic hepatitis B, infection and its treatment: HBsAg, hepatitis B, e-antigen HBeAg, hepatitis B, surface antibody anti-HBs IgG, hepatitis B, e antibody anti-HBe IgG and HBV DNA. HBeAg, HBV-DNA and DNA polymerase appear in serum soon after HBsAg, and all signify active viral replication. Persistence of HBeAg is an impoant indicator of continued viral replication, infectivity and probable progression to chronic hepatitis. To detect previous exposure to hepatitis B, in a person who is immune compromised when the virus can become reactivated: hepatitis B, core antibody anti-HBc total and anti-HBs 