<prompt> Lowes syndrome is characterised by the following exceptHypophosphatamic ricketsUndescended testesDefect in the CNS and eyesAminoaciduria  <response>: Lowes syndromeIt is also known as an oculocerebrorenal syndrome of Lowe.It is an X-linked disorder.It is characterized by :i Congenital cataractii Mental retardationiii Fanconi syndrome AminoaciduriaThe disease is caused by a mutation in the OCRL1 gene, which encodes the phosphatidylinosital polyphosphate 5-phasphatasq.Clinical featuresProgressive growth failure o Hypotonia Blindness Fanconi syndrome Renal inefficiency Behavioural problems Significant proteinuria 