<prompt> Wilsons disease is characterized by ?Increased serum ceruloplasminDecreased copper excretion in urineIncreased copper in liverAutosomal dominant  <response>: Ans. is c i.e., Increased copper in liver Diagnosis of Wilson disease The gold standard for diagnosis is liver biopsy with quantitative copper assay - concentration of copper in a liver biopsy sample 200 mgg dry weight. Other tests are ? Serum ceruloplasmin level - low Urine copper excretion - increased KF rings DNA Haplotype analysis. 