<prompt> All of the following are true about toxic megacolon EXCEPT: March 2013 gCarries significant risk of perforationConsistent feature of Crohns diseaseColonic dilatationColectomy may be required  <response>: Ans. B i.e. Consistent feature of Crohns disease In cases of ulcerative colitis, inflammation and inflammatory mediators can damage the muscularis propria and neuromuscular function leading to colonic dilation and toxic megacolon. 