<prompt> Heparin is contraindicated in patients suffering from the following diseases exceptBleeding due to defibrination syndromePulmonary tuberculosisSubacute bacterial endocarditisLarge malignant tumours  <response>: HEPARIN Contraindications 1. Bleeding disorders, history of heparin induced thrombocytopenia. 2. Severe hypeension risk of cerebral haemor rhage, threatened aboion, piles, g.i. ulcers risk of aggravated bleeding. 3. Subacute bacterial endocarditis risk of embolism, large malignancies risk of bleeding in the central necrosed area of the tumour, tuberculosis risk of hemoptysis. 4. Ocular and neurosurgery, lumbar puncture. 5. Chronic alcoholics, cirrhosis, renal failure. 6. Aspirin and other antiplatelet drugs should be used very cautiously during heparin therapy. Ref:- kd tripathi; pg num:-619 