<prompt> Excitatory ncurotransmitter in brain isAchAdrenalineNoradrenalineDopamine  <response>: A Ach Acetylcholine ACETYCHOLINE is distributed throughout the CNS, with high concentrations in the cerebral cortex, thalamus, and various nuclei in the basal forebrain. Ach was the first neurotransmitter discovered and is the major neurotransmitter in the peripheral nervous system, Ach is excitatory in contract to monoamine neurotransmitters which are nearly always inhibitory. Primary monoamine neurotransmitters are dopamine, norepinephrine and serotonin. Dopamine and epinephrine are primarily inhibitory neurotransmitters that produce arousal. 