<prompt> Drug induced pseudomembraneous colitis is caused byCl.perfringensCl.difficileCl.tetaniFusobacterium  <response>: Ans: b Cl.difficile CLdifficile is a gram positive bacillus Non haemolytic, saccharolytic, weakly proteolytic Pseudomembraneous colitis is due to enterotoxin toxin A cytotoxin toxin B and Binary toxin The toxin is neutralised by Clostridium sordelli antitoxin Drug of choice: Metronidazole Most common clinical feature: diarrhoea Entire colon is affected in 90 patients, 70 have rectal sparing Most sensitive test: stool culture for Cl.difficile Probiotic medicine in treatment of it: saccharomyces boulardi Drugs, causing this : clindamycin, ampicillin, cephalosporins ceftriaxone, cefotaxim, cefuroxime, ceftazidime fluoroquinolone ciprofloxacin, levofloxacin, gatifloxacin, moxifloxacin 