<prompt> A child few hours after ingestion of a fruit, vomiting started later developed convulsion. In the hospital his blood glucose was very low, but no ketone bodies. The fruit he ingested was identified as a fruit found in Africa. What is the diagnosis?MCAD deficiencyZellweger syndromeCarnitine deficiencyJamaican vomiting sickness  <response>: Ans. D. Jamaican vomiting sickness The fruit given in picture is Ackee apple fruit seen in Africa. The fruit contains a toxin hypoglycin that inhibit acyl-CoA dehydrogenase. Lack of beta oxidation results in lack of ATP and acetyl-Co A, which decreases gluconeogenesis. This result in hypoglycaemia. No ketone bodies due to lack of beta oxidation. 