<prompt> Which of the following is granted orphan drug status for the treatment of Dravets syndrome?StiripentolIcatibantPitolisantTafamidis  <response>: StiripentolStiripentol increases GABA transmission. It is granted orphan drug status for the treatment of Dravets syndrome Severe myoclonic epilepsy in infants.Icatibant is a bradykinin B2 receptor antagonist. It is used for acute attacks of hereditary angioedema in adults with C1-esterase inhibitor deficiency.Pitolisant aka Tiprolisant is a inverse agonist of H3 receptor. It is under trial for schizophrenia and Parkinsons disease.Tafamidis stabilizes the correctly folded tetrameric form of TTR. It is used in familial amyloid polyneuropathy. 