<prompt> Most common organs involved in Wegeners granulomatosis are:Skin and noseLung and kidneyHea and kidneyKidney and nervous system  <response>: Wegener granulomatosis also known as Granulomatosis with polyangiitis The most common organs involved in Wegeners are lungs and kidneys. PR3-ANCAs are also present in maximum cases. PR3 ANCAs are useful markers of disease activity Histological features : -Upper respiratory tract : lesions shows granulomas with central necrosis and accompanying vasculitis. -Kidney : Focal necrotizing and often crescentic glomerulonephritis. 