<prompt> A 50 year old diabetic and hypertensive patient on amlodipine and glimepiride is posted for elective AV fistula creation for dialysis in view of acute kidney failure. What is your view as anaesthesiologist with regard to pre-operative ordersStop amlodipine but continue glimepirideContinue amlodipine , stop glimepiride and switch over to insulin a day priorStop both amlodipine and glimepiridePut patient on insulin and schedule surgery only after a week.  <response>: Anti hypertensive and oral hypoglycemic drugs should not be stopped. In a major surgery insulin should be started instead of oral hypoglycemic agents. 