<prompt> Lipoprotein A shows homology with:PlasminogenAlbuminProthrombinPlasmin  <response>: Refer: Harpers Illustrated Biochemistry, 27th editionLipoprotein A, Lp aLp a is a lipoprotein similar to LDL in lipid and protein composition, but it contains an additional protein called apolipoproteina Apo a is synthesized in the liver and attached to apoB-100 by a disulfide linkage.The major site of clearance of Lpa is the liver, but the uptake pathway is not known.Lp a causes fibrin complex deposition.Lp a has structural similarity with Plasminogen.Inhibits the tissue plasminogen action.Inhibits the solubilization of fibrin by the action of plasmin.Oxidized Lp a taken up by macrophages.Lp a as a risk factor for atherosclerotic diseases such as coronary heart disease and stroke. 