<prompt> About Apoptosis ,true statement isInjury due to hypoxiaInflammatory reaction is presentCouncil man bodies are associated with ApoptosisCell membrane is damaged  <response>: Ref Robbins 8e p25; 7e p26;9e p823 Councilman body, also known as Councilman hyaline body or apoptotic body, is an acidophilic eosinophilic pink-staining on HE globule of cells that represents a dying hepatocyte often surrounded by normal parenchyma. ... It represents a hepatocyte that is undergoing necrosisapoptosis In HE-stained tissue sections, the nuclei of apoptotic cells show various stages of chromatin condensation and aggregation and, ultimately, karyorrhexis Fig. 1-21; at the molecular level this is reflected in fragmentation of DNA into nucleosome-sized pieces. The cells rapidly shrink, form cytoplasmic buds, and fragment into apoptotic bodies composed of membrane-bound vesicles of cytosol and organelles Fig. 1-6. Because these fragments are quickly extruded and phagocytosed without eliciting an inflammatory response, even substantial apoptosis may be histologically undetectable 