<prompt> Protein synthesis occurs in:Golgi bodiesEndoplasmic reticulumMitochondriaPeroxisomes  <response>: Ans. b Endoplasmic reticulumRef: Harper s Biochemistry 30,h ed. pg. 576-77 The surface of the rough endoplasmic reticulum is studded with protein-manufacturing ribosomes giving it a rough appearance. The ribosomes bound to ER are not a stable part of this organelles structure as they are constantly being bound and released from the membrane. A ribosome only binds to the RER once a specific protein-nucleic acid complex forms in the cytosol. This special complex forms when a free ribosome begins translating the mRNA of a protein destined for the secretory pathway. Protein once produced from RER will go to golgi apparatus - secretory vesicles - which is further released. 