<prompt> L.E. cell is a -LymphocyteNeutrophilBasinophilEosinophil  <response>: Ans. is b i.e., Neutrophil o In SLE, antinuclear antibodies ANPs can not penetrate intact cells. o However, nuclei are exposed, ANA can bind to them. o In tissues, nuclei of damaged cells react with ANAs, lose their chromatin pattern, and become homogeneous, to produce lupus - erythematous LE bodies or hemotoxylin bodies. o When these LE bodies are engulfed by phagocytic cells neutrophil or macrophagemonocyte, the phagocytic cells are called LE cells. 