<prompt> Drug of choice for typhoid fever:CiprofloxacinAmpicillinChloramphenicolTetracycline  <response>: Ans: a Ciprofloxacin Ref: Harrison, 16th ed,p. 900Ciprofloxacin is the drug of choice for enteric fever, dose is 500 mg PO b.i.d for 10 days.The Table gives below is from Harrison. 17th edition.Antibiotic therapy for enteric fever in adultsIndicationAgentDosage RouteDuration, DaysEmpirical Treatment Ceftriaxone1-2 gd IV7-14 Azithromycin1 gd PO5Fully Susceptible Ciprofloxacin first line500 mg bid PO or 400 mg q12h IV5-7 Amoxicillin second line1 g tid PO or 2 g q6h IV14 Chloramphenicol25 mgkg tid PO or IV14-21 Trimethoprim-160 800 mg bid PO14 sulfamethoxazole Multidrug--Resistant Ciprofloxacin500 mg bid PO or 400 mg q12h IV5-7 CeftriaxoneAzithromycin2-3 gd IV1 gd poy7-145Nalidixic Acid-Resistant Ceftriaxone1-2 gd IV7-14 Azithromycin1 gd PO5 High-dose ciprofloxacin750 mg bid PO or 400 mg q8h IV10-14 