<prompt> Prognosis of melanoma depends ona Stageb Depth of melanoma of biopsyc Duration of growthd Siteacdbcdabdab  <response>: Prognosis of melanoma depends most importantly on staging. The most current staging system of AJCC takes into account following factorsdepth of invasion Breslows thickness - this is the single most important prognostic factorulceration - presence of ulceration carries worse prognosis.lymph node statussatellite lessiondistant metastasisOther prognostic factor not included in stagingSite or anatomic location - people with lesion of the extermities have a better prognosis than people with melanomas of the head neck or trunk. feet and mucous membrane also have poor prognosis- HarrisonGender -females have better prognosis than malesHistologic type - Lentigo maligna has best prosnosis acral lentiginous worst.Old age especially 60 have poorer prognosis.Also knowThe factor that most closely correlates with local recurrence is primary tumor ulceration Sabiston 18e p774 