<prompt> Acanthosis nigricans is associated with malignancies and: March 2013HypeensionMIInsulin resistanceLeprosy  <response>: Ans. C i.e. Insulin resistance Acanthosis nigricans Characteristic of acanthosis nigricans: - Dark, - Thick, - Velvetty skin in body folds and creases MC cause of acanthosis nigricans: Type 2 DM Internal malignancies associated with acanthosis nigricans: - Adenocarcinoma lungs, - Carcinoma GIT etc. 