<prompt> A patient presents with history of bullae involving 30 BSA along with rashes all over body with erosions of the lips and other mucosa for few days. What can be the triggering factor?Viral infectionDrug inducedBacterial infectionIdiopathic  <response>: Ans. B. Drug induced Toxic epidermal necrolysis TEN is a potentially life-threatening dermatologic disorder characterized by widespread TEN involves more than 30 of the body surface, whereas SJS involves less than 10 erythema, necrosis, and bullous detachment of the epidermis and mucous membranes, resulting in exfoliation and possible sepsis andor death. Mucous membrane involvement can result in gastrointestinal hemorrhage, respiratory failure, ocular abnormalities, and genitourinary complications. TEN is most commonly treated by drug-induced antibiotics sulfonamides, antiepileptic drugs Phenobarbital, Phenytoin, nonsteroidal anti-inflammatory drugs NSAIDs, ampicillin, allopurinol, and the antiretroviral drugs nevirapine, abacavir. The mainstay of treatment is supportive care until the epithelium regenerates. 