<prompt> A woman with Ho recurrent abortions presents with isolated increase in APTT. Most likely cause is:Lupus anticoagulantFactor VIIVon Willebrands diseaseHemophilia A  <response>: Ans. is a, i.e. Lupus anticoagulantRef. Dutta Obs. 6e, p 343; Fernando Arias 3e, p 327; Leon Speroff 7e, p 1082Isolated increase in APTT is suggestive of lupus anticoagulant. 