<prompt> In high risk population, HCC is best detected by:USGCTMRIPET scan  <response>: Ans. a USGRadiological Investigations for HCC:Imaging Investigation of Choice- Triple Phase CECT abdomenClassical features are: Arterial Hyper vascularization Early Wash out in Venous PhaseSmall HCC in Three phases is shown here. See the enhancement in arterial phase and wash out in Venous PhaseHCC Confirmation: As per NCCN guidelines 2015 For lesions 1-2cm: 2 Imaging techniques CECT and MRI Focal Lesions 2cm: One imaging technique with Arterial Hyper vascularization and venous wash out is enough. Screening is based on USG Scanning of High risk population Like HBV induced Cirrhosis Biopsy is not required to prove its an HCC. INFACT MUST NOT BE TAKEN 