<prompt> Most common gene involved in Noonan syndromePTCN 11PTPN 11PTPN 22PTCN 22  <response>: NOONAN SYNDROME: - Autosomal dominant, Normal karyotype - MC gene involved -- PTPN 11 - Seen in both boys girls -- FEILE - FEATURES: Sho stature webbed neck Anti-mongoloid slant eyes Opposite of Down syndrome Cubitus valgus Clinodactyly, Cryptorchidism cardiac anomalies: Supra valvular Pulmonary Stenosis --, HOCM, ASD Presence of Intellectual disability 