<prompt> Hypercoagulability due to defective factor V gene is called:Lisbon mutationLeiden mutationAntiphospholipid syndromeInducible thrombocytopenia syndrome  <response>: Mutation in factor V gene is caused by the substitution of glutamine for the normal arginine residue at position 506. It is known as Leiden mutation and it is the most common inherited cause of hypercoagulability. 