<prompt> Which side effect is associated with halothane?HypertensionMalignant hyperthermiaTachycardiaUterine contraction  <response>: Ans is b i.e. Malignant hyperthermia Side effects associated with halothane Halothane causes maximum direct depression of myocardial contractility by reducing intracellular calcium - Contraindicated in severe cardiac disease. It causes fall in BP CO due to myocardial depression - Contraindicated in hypovolemia. It decreases heart rate bradycardia due to vagal stimulation as a result of inhibition of baro-receptor reflex. Halothane has the maximum propensity to sensitize the heart to arrhythmogenic action of adrenaline - Epinephrine should be avoided in doses above 1.5 mgkg. Halothane causes direct hepatotoxicity hepatitis, hepatic necrosis - Contraindicated in patients with acute hepatic disease Jaundice. Halothane causes post anaesthetic shivering, and chills Halothane shakes - Maximum propensity amongst inhalational agents. It can cause malignant hyperthermia. Halothane causes uterine relaxation, Therefore Post partum hemorrhage PPH can occur if used in labor. 