<prompt> Least common site to be involved in osteoahritis amongst the following is:Hip jointKnee jointCarpometacarpal joint of thumbMetacarpophalangeal joint  <response>: Answer is D Metacarphalangeal joints Wrists and Metacarpophalangeal joints are generally not involved in Osteoahritis - Harrison 16th2040 Sparing of wrist and metacarpophalangeal joint with involvement of base of thumb i.e. carpometacarpal joint is very characteristic of osteoahritis. 