<prompt> Histology of Alport syndrome -a Foamy cells in interstitiumb Foamy cells in tubular epithelial cellsc Thickening of GBM 100 nmd Thinning of GBM 100 nme Intimal proliferationbcadab  <response>: Histological characteristics of Alports syndrome: Diffuse basement membrane thinning Vascular sclerosis Foam cells in interstitium Tubular atrophy In advanced stage there is focal or global glomerulosclerosis Interstitial fibrosisOn electron microscopy diagnostic of this disorder, GBM shows Irregular foci of thickening alternating with thinning Pronounced splitting and lamination of lamina densa basket weave appearance. Info: Immunohistochemistry shows failure to stain a-3, 4, 5 collagen. 