<prompt> Which of the following is true regarding Umblical CordOne artery and two veinsPresence of one vein indicates congenital anomalyWharton jelly is the connective tissue of the cordTwo artery only  <response>: Ref. Grays anatomy. 41st edition. Page. 179Umblical Cord: The umbilical cord forms around the fifth week of pregnancy and can grow up to 20 inches long at full-term.Has two main layers: an outer layer of smooth muscle, and an inner layer containing a gelatinous fluid called Whartons jelly.Vasculature - one vein and two arteries. The vein carries oxygen and nutrient-rich blood from the placenta to the fetus, and the arteries carry deoxygenated and nutrient-depleted blood away from the fetus.Clinical Anatomy:Single umbilical artery: Related to congenital anamolies including problems with the heart, nervous system, chromosomes and urinary tract. This problem can be detected before birth.Umbilical cord prolapse: Umbilical cord may prolapse, or slip into the birth canal, and become compressed during delivery, which can cut off the babys blood supplyUmbilical cord knots: It is not uncommon for the cord to become wrapped around the babys neck, but this rarely causes serious problems.Umbilical cord cysts: Sometimes cysts can be seen developing on the umbilical cord via ultrasound. This can lead to abnormalities in the kidneys, chromosomes and abdomen.Vasa previa: In rare cases, umbilical cord blood vessels may shift outside of the protection of the cord and move underneath the baby. This can lead to tears in the vessels and life-threatening bleeding. Pregnant women who experience bleeding in the second or third trimester should seek medical attention to rule out this complication. 