<prompt> Plasmodium falciparum affects all organs exceptLungLiverKidneyHea  <response>: Major complications occur in severe falciparum malaria which may have manifestations of cerebral malaria coma, hypoglycemia, renal impairment, severe anemia, hemoglobinuria, jaundice, pulmonary edema, and acidosis. Ref: Harsh Mohan - Textbook of Pathology, 6th Edition.page no.189 