<prompt> Which drug can be eliminated by nonenzymatic degradationAtracurimPancuroniumMivacuriumDexacurium  <response>: The unique feature of atracurium is inactivation in plasma by spontaneous non-enzymatic degradation Hofmann elimination in addition to that by alkaline ester hydrolysis Consequently, its duration of action is not altered in patients with hepaticrenal i9nsufficiency or hyperdynamic circulation - preferred muscle relaxant for such patients as well as for neonates and the elderlyAtracurium is metabolized to laudanosine that is responsible for seizures.Refer: Morgan and Mikhails Clinical Anaesthesiology, 5th edition, pg no. 216, 269 