<prompt> Hypoglycemia in new born is seen in:a IUGRb Mother with hypothyroidismc Rh incompatibilityd Macrosomiae Hyperthyroidismbadacab  <response>: Hypoglycemia is defined as blood glucose of less than 40 mgdL, irrespective of the gestational age.Causes of hypoglycemia Let us see each option one by one.Option a IUGRHypoglycemia is due to shortage of glycogen reserve in the liver as a result of chronic hypoxiaDutta Obs. 6e, p 465Option b Mother with hypothyroidismMaternal hypothyroidism can cause hypoglycemia if it leads to fetal hypothyroidism also but Maternal TSH receptor bloking antibodies can cross the placenta and cause fetal thyroid dysfunction.They however have little or no effect on fetal thyroid function even though they too cross the placenta..Williams 23e, p 1131, 1132So according to latest editon of Williams, maternal hypothyroidism does not lead to fetal hypothyroidism, thus it does not cause fetal hypoglycemia.Option c Rh incompatibilityThere is no definite correlation between Rhincompatibility and hypoglycemia.Option d MacrosomiaMacrosomia usually is due to maternal diabetes which inturn results in fetal hyperinsulinemia due to beta cell hyperplasia, which further results in neonatal hypoglycemia.Dutta Obs. 6e, p 287Option e Hyperthyroidism : Hyperthyroidism is a diabetes like state with increased insulin resistance. 