<prompt> 35 Year primigravida visited your clinic. USG given below: what is the diagnosis?AnencephalyHoloprocencephalyNuchal translucencyHydrocephaly  <response>: Ans. c Nuchal translucency Ref.: D.C. Dutta 8th ed. 735 Nuchal translucency is a fluid behind the neck of the fetus. It is an anechoic space visible and seen in all fetuses between 11-14 weeks of age The most common cause of increased nuchal translucency 3 mm is aneuploidy where TURNER syndrome is the most common cause followed second by Down syndrome. The reason why it is seen in 11-14 weeks is because at that time fetal lymphatics are developing and peripheral resistance is high and gradually disappears. Remember: Cystic hygroma which is seen in Turner syndrome is high incidence is due to defective development of lymphatics. 