<prompt> Cycin-D IGH fusion gene is associated with?Mantle cell carcinomaFollicular carcinomaMelanomasBurkitt lymphoma  <response>: Burkitt lymphoma is a cancer of the lymphatic system, paicularly B lymphocytes found in the germinal center. It is named after Denis Parsons Burkitt, a surgeon who first described the disease in 1958 while working in equatorial AfricaAll types of Burkitt lymphoma are characterized by dysregulation of the c-myc gene by one of three chromosomal translocations. This gene is found at 8q24. The most common variant is t8;14q24;q32, which accounts for about 85b of cases. This involves c-myc and IGH. A variant of this, a three-way translocation, t8;14;18, has also been identified. A rare variant is at t2;8p12;q24. This involves IGK and c-myc. Another rare variant is t8;22q24;q11. This involves IGL and c-myc. Combined, the two less-common translocations, t2;8p12;q24 and t8;22q24;q11, account for the remaining 15 of cases not due to the t8;14q24;q32 translocation 