<prompt> Which of the following is true about factor V leiden mutation?Increased bleeding tendencyFactor V becomes resistant to cleavage by protein CArginine to glycine substitutionDeficiency of factor V  <response>: Factor V Leiden mutation is hypercoagulable disorder characterized by deep venous thrombosis and pulmonary thromboembolism. Factor V becomes resistant to cleavage by protein C. It occurs due to arginine to glutamate substitution. Factor V deficiency is known as Para hemophilia. 