<prompt> Mrs Reeta Wardhan, A 50-year-old female with rheumatoid ahritis is being considered for infliximab therapy. Which of the following tests should be performed before beginning treatment?Liver function testsPPD skin testPulmonary function testsVisual examination  <response>: Ref: Katzung 11e p633 Infliximab is a monoclona antibody against TNF-a. It is commonly used to treat moderate to severe rheumatoid ahritis paicularly in patients who have failed methotrexate therapy. TNF-a inhibitors can cause serious adverse effects, including reactivation of latent tuberculosis. All patents being considered for TNF-a inhibitor therapy should have a baseline PPD skin test to screen for latent tuberculosis. 