<prompt> Day care surgery usesSodium thiopentonePropofolMethoxitoneEther  <response>: i.e. Propofol: 81-A-Yadav 4thPropofol is the IV agent of choice for day care surgeryBecause-i Early inductionii Early and smooth recoveryiii Inactive metabolitesiv Antiemetic antipruritic Along with opioids alfntanil or renifentanil propofol is the agent of choice for total intravenous anaesthesia TIVA Propofol infusion is used to produce sedation in ICU Agent of choice for induction in susceptible individuals for malignant hyperthermia Propofol is safe in porphyria 373- Wylie AnaesthesiaPROPOFOL 2mgkgIt is oil based preparation containing soya bean oil egg lecithin and glycerol, so injection is painful and should be preceded by lignocaine injection. The colour of solution is milky white and used within 6 hour after opening the vial because there have been death reports following the use of contaminated solution ofpropofol as egg lecithin is good media for bacterial growth and to prevent this problem recently available propofol formulations have disodium edate or sodium metabisulfite as anti microbial agents Mechanism of action is mainly GABA mediated Most common side effect during induction of anesthesia is hypotension. Which is augmented by concomitant administration of opioids 