<prompt> Which one is not converted to an active metabolite?QuinaprilFosinoprilBenzoprilLisinopril  <response>: Lisinopril: It is the lysine derivative of enalaprilat; does not require hydrolysis to become active ACE inhibitor. KEY CONCEPT:-All ACE inhibitors are prodrugs except captopril and lisinopril. Other drugs like enalapril are converted to its active metabolite enalaprilat and thus are slow acting.Reference: Essentials of Medical Pharmacology Eighth Edition KD TRIPATHI page no 532 