<prompt> Baby born prematurely at 29 wks, on examination at 42 weeks with ROP, both eyes shows stage 2 zone 1 plus disease, how will you manage the patient ?Examine the patient after 1 weekLaser photocoagulation of both eyesLaser photocoagulation of worse eye, follow up of other eyeVitreoretinal surgery  <response>: The hallmark of retinopathy of prematurity ROP is abnormal retinal vasculature. Ophthalmologists diagnose and make decisions about the initial treatment of ROP based on the appearance of the retinal blood vessels. Dilatation and tortuosity of the retinal vessels at the posterior pole is termed plus disease. It is a sign of rapidly progressive ROP and is an indication for early laser ablation of the peripheral avascular retina. 