<prompt> A blood donor is not considered for safe transfusion, if he has -Anti FlBsAg veAnti HBsAg and HBcAg veHBsAg ve and IgM anti HBc veAnti HBc ve  <response>: Ans. is c i.e., HBs Ag ye and IgM anti HBc ve . HBs Agve and IgM anti HBc ve indicates acute HBV infection, which is a contraindication of blood tranfusion. About other options Option a . Anti HBs Ag antibody may be ve either after immunization or after recovery from HBV infection. In both the conditions, blood can be transfused. Option b . HBc Ag can not be ve as it does not appear in blood. Option c . When Anti HBe is ve blood can be transfused if other markers of infection are also negative eg: HBsAg, HBV DNA, IgM anti HBC. 