<prompt> An example of a tumour suppressor gene is ?mycfosrasRb  <response>: Ans is d i.e., Rb ProtoncogenesOncogenes Growth factor genes: SIS, HST-1, INT-2, TGFa, HGF. Growth factor receptors genes: ERB-B 1 ECFR, ERB-B2, FMS, RFT, PDGF-R, MT Genes for proteins involved in signal transduction: k-RAS, H-RAS, N-RAS, ABL, BRAF, p-catenin Genes for nuclear regulatory proteins: MYC C-,N-, L-MYC, JUN, FOS Genes for cell cycle regulators: CYCLIN-D, CYCLINE-E, CDK4 Tumor suppressor genes Location Cell surface: TGF-P receptor, E-cadherin Inner aspect ofplasma membrane: NF-1 Cytoskeleton: NF-2 Cytosol: APCP-catenin, PTEN, SMAD2 SMAD4 Nucleus: RB, p53, WT-1, p16 INk4a, BRCA1 BRCA2, KLF 6 