<prompt> Chloride shift is due toGenerationof HCO3 in RBCsMetabolism of glucoses in RBCsFormation of O2-Hb complex in RBCsRelease of K in RBCs  <response>: Chloride shift also known as the Hamburger phenomenon or lineas phenomenon, named after Haog Jakob Hamburger is a process which occurs in a cardiovascular system and refers to the exchange of bicarbonate HCO3- and chloride Cl- across the membrane of red blood cells RBCs Ref: guyton and hall textbook of medical physiology 12 edition page number:360,361,362 