<prompt> Atracurium is metabolized by -ConjugationHoffman degradationPseudocholineateraseMethylation  <response>: Ans. B. Hoffman degradationThe unique feature of atracurium is inactivation in plasma by spontaneous non enzymatic degradation Hofmann elimination.Consequently its duration of action is not altered in patients with hepaticrenal insufficiency or hyperdynamic circulation --- Hence, preferred muscle relaxant for such patients as well as for neonates and the elderly.Atracuum is metabolised to laudanosine that is responsible for seizures.Cause histamine release Hypotension, bronchoconstriction flushing. 