<prompt> Effect of prolonged oxygen therapy is -a Endothelial damageIncreased pulmonary complianceAtelectasisDecreased vital capacity  <response>: More severe problems can include: Lung damage.Atelectasis Fluid buildup or bursting rupture of the middle ear. Sinus damage. Changes in vision, causing nearsightedness, or myopia. Oxygen poisoning, which can cause lung failure, fluid in the lungs, or seizures Ref Davidson 23rd edition pg 545 