<prompt> A 30 year old lady presents with features of malabsorption and iron deficiency anaemia. Duodenal biopsy shows complete villous atrophy. Which of the following antibodies is likely to be present :Antiendomysial antibodiesAnti-goblet cell antibodiesAnti-saccharomyces cerevisae antibodiesAntineutrophil cytoplasmic antibodies  <response>: Answer is A Antiendomysial antibodies: Evidence of Malabsorption together with charachteristic histopathological changes on small intestinal biopsy in the form of complete villous atrophy suggests the diagnosis of celiac spree disease. Antibody studies are frequently used to identify patients with celiac disease. The antiendomysial antibody has 90 to 95 sensitivity and 90 to 95 specificity in the detection of celiac disease. 