<prompt> Pseudopolyps are seen in?Crohns diseaseUlcerative colitisCeliac diseaseTropical sprue  <response>: ANSWER: B Ulcerative colitisREF: Robbins 7th edition page 851, Harrisons Internal Medicine 17th edition chapter 289. Inflammatory Bowel DiseasePseudopolyps are seen with ulcerative colitis not crohns disease Ulcerative ColitisCrohns DiseaseEPIDEMIOLOGY Incidence North America per person-years2.2-14.3100,0003.1-14.6100,000Age of onset15-30 60-8015-30 60-80EthnicityJewish Non-Jewish Caucasian African American Hispanic AsianJewish Non-Jewish Caucasian African American Hispanic AsianMale: Female ratio1:11.1--1.8:1SmokingMay prevent diseaseMay cause diseaseOral contraceptivesNo increased riskOdds ratio 1.4AppendectomyProtectiveNot protectiveMonozygotic twins6 concordance58 concordanceDizygotic twins0 concordance4 concordancePATHOLOGY DistributionDiffuseSkip lesionsInflammationLimited to mucosaTransmuralPseudopoiypsMarkedNo to slightUlcersSuperficialDeep linearGranulomaNoYes 50FistulaSinusesNoYesCLINICAL Gross blood in stoolYesOccasionallyMucusYesOccasionallySystemic symptomsOccasionallyFrequentlyPainOccasionallyFrequentlyAbdominal massRarelyYesSignificant perineal diseaseNoFrequentlyFistulasNoYesSmall-intestinal obstructionNoFrequentlyColonic obstructionRarelyFrequentlyResponse to antibioticsNoYesRecurrence after surgeryNoYesANCA-positiveFrequentlyRarelyASCA-positiveRarelyFrequentlyENDOSCOPIC Rectal sparingRarelyFrequentlyContinuous diseaseYesOccasionallyCobblestoningNoYesGranuloma on biopsyNoOccasionallyRADIOGRAPHIC Small bowelNoYessignificantly abnormal Abnormal terminal ileumOccasionallyYesSegmental colitisNoYesAsymmetric colitisNoYesStrictureOccasionallyFrequentlyNote: ANCA. antineutrophil cytoplasm antibody; ASCA, Anti-Sacchanomyces cerevisiae antibody. 