<prompt> Which malignancy would occur in long standing multinodular goiter ?Papillary CarcinomaFollicular CarcinomaAnaplastic CarcinomaMedullary Carcinoma  <response>: Incidence of follicular carcinoma is high in endemic goitrous areas, with long standing multinodular goiter, possibly owing to persistent TSH stimulation.Dominant or rapidly growing nodules especially in longstanding goiters should always be subjected to aspiration cytology. 