<prompt> Marker for infectivity of serum in Hepatitis B isHBsAgAnti-HBcHBeAgAnti Hbc  <response>: Markers of Hepatitis B infection in order of appearance in serum : HBsAg Hepatitis B Surface antigen : Also known as ;Australian antigen; First antigen to appear in serum- ;first evidence of infection; ;Epidemiological marker of Hepatitis B infectionHBcAg Hepatitis B core antigen Alone doesnot appear in serum HBeAg Hepatitis B envelope antigen Is secretory form of HBcAg Indicates active viral replication Is a marker of infectivity for Hepatitis B Persistence beyond 3 months: Increased likelihood of chronic Hepatitis B. AntiHBc Antibody to Hepatitis B core antigen First antibody to appear in serum IgM Anti-HBc indicates a diagnosis of acute Hepatitis B IgG Anti-HBc persists indefinitely Anti-HBe Antobody to Hepatitis B envelope antigen Signals ;stoppage of active viral replication Indicates end of period of infectivity Anti-HBs Antibody to Hepatitis B surface antigen Last antibody to appear in serum Signals ;recovery, end of period of communicability; Ref: Park 25th edition Pgno: 235 