<prompt> Most common organism causing osteomyelitis:Staph AureusStrep pneumoniaH. InfluenzaE. coli  <response>: Ans. a Staph AureusRef: Maheshwari 5th ed. 168Note that responsible pathogens may be isolated in only 35- 40 of infections. Bacterial causes of acute hematogenous and direct osteomyelitis include the following: Most common organism causing acute osteomyelitis: Staph. Aureus MCC of osteomyelitis in sickle cell anemia patient: SALMONELLA MCC of osteomyelitis in IV drug abuser: PSEUDOMONAS MC organism causing osteomyelitis in open foot injury: PSEUDOMONAS MC organism causing osteomyelitis in HIV patient: Staph. Aureus MC organism causing osteomyelitis in case of animal bite: Pasteurella Multiocida MC organism causing osteomyelitis in case of human bite: Eikenella Corrodens 