<prompt> The concentration of hydrocioinone for treating cholasma should be-1lto 22 to 510  <response>: C i.e. 2-5 - Light brown butterfly rash without systemic involvement in pregnancy and on OCPQ is seen in chloasma. Whereas erythematous red phostosensitive butterfly rash with multisystem multi organ involvement like ahritis, nephritis, Raynauds phenomenon etcQ is seen in SLE. - Hydroquinone, the most effective topical bleaching agent is used in 2-4 concentration in chloasma. ChloasmaMelasmaMask of SLE pregnancy - Dusky red erythematous - Light brown macules rash or photosensitive pigmentationQ. pigmentationQ - Associated with multi-organ - Associated with pregnancy most involvement like common, OCPQ, menstrual ahritisahralgia, nephritis, disturbance in unmarried girls raynauds phenomenon etcQ. persistent anemia - More common in females - More common in females on bridge involving bridge of nose of nose cheeks malar eminence. cheeks i.e. malar eminence Linear area just above eyebrows is malar butterfly rash usually involved and area between nose upper lip and skin around eyes as a rule spared. Photodermatitis - In farmers, sailors, labourer in professions, which keep them in sun for prolonged periods - Scally read lesionsQ in sun exposed areas Rosacea Recurrent episodes of bright red erythema and hot flushes on face, mostly in females nearing their menopause, triggered by emotional tension, hot spicy food beverages. Later on erythema becomes persistant and telengectasia appears on nose, cheeks and chin. 