<prompt> All the following are angiogenic factors EXCEPT ?VEGFPDGFIFNTGF3  <response>: Ans. is c i.e., IFN Angiogenesis o Angiogenesis is the physiological process involving the growth of new blood vessels from pre-existing vessels. o Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in granulation tissues. o Angiogenesis is also impoant for growth and distant metastasis tumors. o There are various factors the stimulate angiogenesis, called angiogenic factors: Angiogenin Angiopoietin-1 Del-1 Fibroblast growth factors: acidic aFGF and basic bFGF Follistatin Granulocyte colony-stimulating factor G-CSF Hapatocyte growth factor HGFscatter factor SF Interleukin-8 IL-8 Leptin Midkine Placental growth factor Platelet-derived endothelial cell growth factor PD-ECGF Platelet-derived growth factor-BB PDGF-BB Pleiotrophin PTN Proliferin Transforming growth factor-alpha TGF-alpha Transforming growth factor-beta TGF-beta Tumor necrosis factor-alpha TNF-alpha Vascular endothelial growth factor VEGFvascular permeability factor VPF. o Impoatn angiogenesis inhibitors are: Soluble VEGFR-1 and NRP-1 Angiopoietin2 TSP-1 TSP-2 Angiostatin, Vasostatin, Calreticulin, Canstatin Platelet factor 4 PF4 Meth-1 and meth-2 IFN a, fi, y Prolactin Osteopontin Maspin VEGI, SPSRC, TIMP, CDAI 