<prompt> All of the following statements about pralidoxime in organophosphate poisoning are true except:-It is given intravenouslyIt should be staed after 24 hours of poisoningIt does not cross blood brain barrierReactivates the AChE enzyme  <response>: Organophoshate poisoning - AchE inhibit Acetyl cholinestrase enzyme Atropine is drug of choice for organophosphate poisoning Atropine reverses the symptom by blocking receptors Organophosphate poisoning DRUG OF CHOICE- Atropine Pralidoxime Reactivate Inhibit Receptors Ache enzyme All the oximes are given Intra venously PAM Pralidoxime - periphery do not cross blood brain barrier DAM Diacetyl monoxime - both in the brain and outside the brain Oximes should be staed as soon as possible after atropine is given If we take long time enzyme aging may occur enzyme cannot work 