<prompt> All of the following are true for mitral valve prolapse, EXCEPT:Transmission may be as an autosomal dominantMajority of the case present with features of mitral regurgitationThe value leaflets characteristically show myxomatous degenerationThe disease is one of the common cardiovascular manifestations of Marfans Syndrome  <response>: Most cases of MVP are asymptomatic and remain so for their entire lives, However MVP is one of the most common cause in patients presenting with isolated severe MR requiring surgical treatment. Though MR is common, they are definitly not the presenting feature in the majority of the patients. ALl other features mentioned above are associated with MVP. So majority of the cases present with features of mitral regurgitation is the single best answer of choice. Ref: Harrisons Principles of Internal Medicine, 16th Edition, Page 1395; R Alagappan, Manual of Practical Medicine, 3rd Edition, Pages 149, 150. 