<prompt> In maturity onset diabetes on the young mody not found is.Family history positiveYoung onsetInsulin receptor resistanceGlucokinase deficiency  <response>: D Glucokinase deficiency 2968- H 18ThMaturity- onset diabetes of the young MODY Single gene defect with autosomal dominant inheritance Early onset of hypoglycemia usually 25 years Mutations in the insulin receptors cause a group of rare disorders characterized by severe insulin resistance MODY - ie noninsulin requiring diabetes presenting before theage of 25 years, very rarely, diabetes can develop at or soon after birth. This neonatal diabetes is usually genetic in origin with 50 due to mutations in the KATP channel of the pancreatic B cell causing insulin deficiency and diabetic ketoacidosis. However sulphonyl urea drugs overcome the defect in potassium channel signaling, so that insulin therapy is not necessary in these patients 807- Dividson 22nd The genetic mutation seen in the most common type of MODY is Hepatocyte Nuclear factor 1 one 