<prompt> In TB, immunity is provided by -CD 4CD 8IgGIgM  <response>: Ans. is a i.e., CD4 . Cell mediated immunity confers protection against M. tuberculosis, while humoral immunity has no defined role in protection. . Two types of cells are essential. 1. Macrophages -- Directly phagocytize tubercle bacilli. 2. T cells mainly CD4 -- Induce protection through the production of IFN-y 