<prompt> Albinism -Hair bulb for tyrosine positivity test is useful only vhen the child is 5 years oldIs associated with platelets abnormality especially with aspirinComplete decussation is invariable in all albinismIs associated with thrombosis under general anaesthesia  <response>: Hermansky-Pudlak syndrome or abbreted HPS is an extremely rare autosomal recessive disorder which results in oculocutaneous albinism decreased pigmentation, bleeding problems due to a platelet abnormality platelet storage pool defect, and storage of an abnormal fat. Ref Davidson 23rd edition pg 1311 