<prompt> Steroid refractory ulcerative colitis is said to be present in a patients who have active disease despite:Prednisolone up to 0.5 mgkgday over a period of 4 weeksPrednisolone up to 0.75 mgkgday over a period of 4 weeksPrednisolone up to 1 mgkgday over a period of 4 weeksPrednisolone up to 1.5 mgkgday over a period of 4 weeks  <response>: Patients with ulcerative colitis who have active disease despite prednisolone up to 0.75 mgkgday over a period of 4 weeks is called steroid refractory. Also know: Steroid-dependent colitis Unable to reduce steroids below the equivalent of prednisolone 10 mgday within 3 months of staing steroids, without recurrent active disease, or Those who have a relapse within 3 months of stopping steroids. Ref: Journal of Crohns and Colitis 2012 6, 965-990 