<prompt> A recently diagnosed case of small cell carcinoma of lung presented with slowly progressive proximal muscle weakness along with ptosis of eyelids and diplopia. OE: - DTRs-absent Autonomic dysfunctions like frequent dryness of mouth were present. The doctor advised repetitive nerve stimulation test. There was increase in compound muscle action potential amplitude and this increase was 100 following exercise or with high frequency repetitive nerve stimulation. On serological testing, antibodies will be found against which channels: -T-type of calcium channelsPQ type of calcium channelsL type of calcium channelsN- type of calcium channels  <response>: This is a case of Lambe Eaton syndrome occurring in the setting of small cell carcinoma of lung. RNS study shows incremental response which goes in or of Lambe Eaton syndrome LEMS. Lambe-Eaton syndrome Presents with proximal muscle weakness Ptosis and diplopia Absent DTRs. Autonomic dysfunction Autoantibodies directed against PQ-type calcium channels at the motor nerve terminals Found in 85 of LEMS patients. These impair the release of ACh from nerve terminals. In older adults, most LEMS is associated with malignancy. Most common malignancy associated is commonly small-cell lung cancer SCLC 