<prompt> Most common cause of death in adult with PDA is- 1. CCF 2.Infective endocarditis 3. Rupture 4. Embolismonly 1Both 1 and 41, 2 and 3Both 1 and 2  <response>: The leading causes of death in adults with patent ductus are cardiac failure and infective endocarditis; occasionally severe pulmonary vascular obstruction may cause aneurysmal dilatation, calcification, and rupture of the ductus. Harrison;s principle of internal medicine,18th edition,pg no. 1924 