<prompt> Malate shuttle is impoant in:Liver and HeaBrain and HeaBrain and Skeletal muscleLiver and Skeletal muscle  <response>: Malate shuttle is more impoant in the liver and cardiac muscles as these organs require a continuous supply of energy. Whereas Glycerol-P-shuttle is a shoer shuttle and provides a quick source of ATPs as compared to the Malate shuttle. So it is present in brain skeletal muscles, where energy is needed quickly in case of an emergency. 