<prompt> Thalidomide used for multiple myeloma isAssosciated with diarrheaCharacterised by enantiomeric interconvesionsMetabolized extensively by hepatic CYP systemSafe for use in pregnant females  <response>: Refer Katzung 10th919 Thalidomide used for morning sickness but later withdrawn due to teratogenic effects It is not extensively metabolized by microsomal enzymes It is now used for multiple myeloma It can also result in constipation ,peripheral neuropathy 