<prompt> True about Crigler Najjar type II syndrome is:Diglucuronide deficiencyRecessive traitKernicterus is seenPhenobarbitone is not useful  <response>: Answer is B Recessive trait Crigger Najjar syndrome is inherited as an autosomal recessive trait. Crigger Najjar Syndrome Type H is associated with a deficient activity of Bilirubin UDP - Glucoronyl Transferase activity UGITAL and not with dimlucornide deficiency. Kernincterus is a characteristic features of type 1 Criggler Najjar syndrome and Kernincterus is extremely rare in type 11 Criggler Najjar syndrome. Phenobarbital is extremely effective and useful in type 11 Criggler Najjar syndrome and reduces bilirubin levels by 25. Principal Characteristics Criggler-Najjar Syndromes Feature Crigler-Najjar Syndrome Typel Type II Total serum bilirubin, pmolL mgdl 310-755 usually 345 100-430 usually 345 Routine liver tests Normal Normal Response to Phenobarbital None Decreases bilirubin by25 Rare Kernicterus Usual Hepatic histology Normal Normal Bile characteristics Color Pale or colorless Pigmented Bilirubin fractions monoconjugates 90 unconjugated Largest fraction mean: 57 Bilirubin UDP-glucuronosyl-transferase Typically absent; traces in some patients Markedly reduced:0-10 of normal Inheritance all autosomal Recessive Predominantly recessive 