<prompt> SE of OC pills is -DysmenorrhoeaProlactin levelCarbohydrate intoleranceEndometriosis  <response>: Ans. is c i.e., Carbohydrate intolerance Adverse effects of OCPs c Nausea, vomiting, headache migraine may be worsened. o Breakthrough bleeding or spotting, Amenorrhoea o Breast discomfo mastalgia o Weight gain, acne and increased body hair. o Cholasma, pruritus vulvae o Carbohydrate intolerance o Mood swing, abdominal distention especially with minipill. o Leg vein and pulmonary thrombosis. Coronary cerebral thrombosis -- MI, stroke u Estrogen component is responsible for venous thromboembolism. Both estrogen and progesterone are responsible for the aerial phenomena. o Mechanisms involved may be ? I. Increase in the blood clotting factors II, VII, IX, X Decrease antithrombin III and plasminogen activator. Increased platelet aggregation. o Rise in BP T risk of breast and cervical carcinoma risk of endometrial and ovarian carcinoma decreases o Benign hepatoma - may turn into malignant. Gall stones. Remember o Estrogen increases the risk of endometrial cancer. o Progesterone component decreases this risk in OC pills. o Estrogen has orable effect on lipid profile, while progesterone has opposite effect. o Progesterone component is mainly responsible for MI. 