<prompt> Most common cause of death in Menke diseaseCardiac ruptureDiaphragmatic paralysisLaryngeal spasmCyano-methemoglobinemia  <response>: Menkes disease, also known as kinky hair disease, is an X-linked neurodegenerative disease of impaired copper transpo The major problems in Menkes disease involve the neurologic, gastrointestinal, and connective tissue including blood vessels systems. Pneumonia, leading to respiratory failure, is a common cause of death and also diaphragmatic paralysis Ref Robbins 9e pg 170 