<prompt> In which of the following age group myelodysplastic syndrmome MDS are most common:10-Feb15-205q50  <response>: Answer is D 50 years Idiopathic MDS is a disease of the elderly. The mean age of onset is 68 years. Myelodysplastic Syndromes Disease of the elderly with mean onset 68 years Heterogenous group of haematological disorder Characterized by - Peripheral blood cytopenias - Trilineage dysplastic changes - Hypercellular bone marrow - Propensity to undergo transformation into Acute Myeloid LeukaemiaQ. The French American British Group has classified this disorder into 5 pathological entities - Refractory Anemia - Refractory Anemia with ring sideroblasts - Refractory Anemia with Excess blasts - Refractory Anemia with Excess blasts in transformation - Chronic Myelomonocytic Leukaemia 