<prompt> Which one of the following diseases characteristically causes a fatty change in liver?Hepatitis B virus infectionWilsons diseaseHepatitis C virus infectionChronic alcoholism  <response>: Alcoholic liver disease ALIT is the most frequent secondary fatty liver disease. The secondary fatty liver can also occur in chronic Viral hepatitis C HCV, chronic viral hepatitis, chronic autoimmune hepatitis AIH, and Wilsons disease Thus although fatty liver may be seen secondary to all options mentioned in the question chronic alcoholism being the most common cause is the single best answer here.Following information have been added in 8the of Robbins Non alcoholic fatty liver disease NAFLDIt has become the most common cause of chronic liver disease in united states NAFLD includes:Simple hepatic steatosis Stable conditionsSteatosis with inflammation Stable conditionsNon-alcoholic steatohepatitis NASH Can progress to cirrhosisNAFLD is the most common cause of cryptogenic cirrhosis cirrhosis of unknown origin. 