<prompt> Alkylating agent used in chemotherapy:MechlorethamineProcarbazineCyclophosphamideAll of the above  <response>: Ref: KDT pg. 819-20; Katzung, 11th ed. pg. 1280 Bleomycin: This is a mixture of closely related glycopep- tides antibiotics having potent antitumour activity. It is highly effective in testicular tumour and squamous cell carcinoma of skin, oral cavity, head and neck, genitourinary tract and esophagus. Side effect: pulmonary fibrosis and myelosuppression.Alkylating agents have cytotoxic and radiomimetic actions. They are mainly cell cycle non-specific, i.e. act on dividing as well as resting cells. Cross-linking of DNA appears to be of major importance to the cytotoxic action of alkylating agents, and replicating cells are most susceptible to these drugs. Drugs are:Alkylating agents- cell cycle- nonspecific agentsAntimetabolites- cell cycle- specific agentsNitrogen mustard Cyclophosphamide Ifosfamide Mechlorethamine Melphalan ChlorambucilFolic acid antagonist:MethotrexatePurine analogues 6 Mercaptopurine 6thioguanine Cladribine FludarabineDrugs acting by Methylation Procarbazine Dacarbazine TemozolomidePyrimidine analogues Capecitabin Gemcitabin Cyatarabine and 5 FUNitrosoureas Carmustine Lomustine Semustine StreptozocinMiscellaneous Busulfan Altretamine Thiotepa Trabectadin 