<prompt> Local anaesthetics acts by inhibiting: March 2012Sodium channelsPotassium channelsCalcium channelsMagnesium channels  <response>: Ans: A i.e. Sodium channels Local anaesthetics act by inhibiting sodium channels from inside Local anesthetics Generally blocks: Sodium channels Potency of LA depends on: Lipid solubility Susceptibility of fibres to LA: Type B type C type A Amide linked LA: - Lidocaine, - Bupivacaine etc. Ester linked LA: - Cocaine, 