<prompt> I-cell disease is associated withGolgi apparatusLysosomesPeroxisomesMitochondria  <response>: Mutations in proteins of the plasma membrane, with one affecting lysosomal function I-cell disease.I-cell disease - Mutations in the gene encoding GlcNAc phosphotransferase, resulting in absence of the Man 6-P signal for lysosomal localization of ceain hydrolases 