<prompt> Essential for tumor metastasis is -AngiogenesisTumorogenesisApoptosisInhibition of tyrosine kinase  <response>: Harshmohan textbook of pathology 7th edition. tumour angiogenesis play a very significant role in metastasis since the new vessels formed as apa of growing Tumor are more vulnerable to invasion because this evolving vessels are directly in contact with cancer.. 