<prompt> Most common antibody in sjogren syndromeAnti-DNA topoisomeraseAnti-CentromereAnti-RNA polymeraseAnti-Ribonucleoprotein  <response>: Ans. d Anti-RibonucleoproteinRef: Robbins 9thpg218; 8thpg213Autoantibodies in Sjogrens syndrome:Anti SS-A Ro and SS-B La Q: Most important, present in 90 patients;High titers of Anti SS-A - more likely to have early disease onset, longer disease duration, and extra- glandular manifestations eg cutaneous vasculitis and nephritisRheumatoid factor an antibody reactive with self IgG: in 75 Q, ANA: in 50 to 80 