<prompt> Total lung capacity is not increased inAsthmaAcromegalyEmphysemaInterstitial lung disease  <response>: Ans: d ILDRef: Harrison, 17th ed. pg. 1646ILD is a restrictive lung disease characterized by decrease in both total lung capacity as well as residual volume.ParameterObstructive lung diseaseRestrictive lung diseaseTotal lung capacityNormal to IncreaseDecreasesResidual volume VitalIncreasesDecreasescapacity FEV,FVCDecreasesDecreasesFEV FEF 25-75DecreasesNormal toForced expiratory flowDecreases NormalIncreaserate Diffusion capacityDecrease in emphysemaNormal DecreasedOut of the four options given, shigellosis is the single best answer of exclusion:Shigellosis clinical manifestations: Incubation period 1 - 4 days Diarrhoeal phase - fever, vomiting, tenesmus, watery diarrhoea Dysenteric phase - small volume bloody mucopurulent stools , acute colitis Post infectious phaseComplications: Intestinal - toxic megacolon, intestinal perforation, rectal prolapsed Metabolic - dehydration, hyponatraemia, hypoglycaemia HUS - ARF occurs in 55-70 cases Ekiri syndrome - toxic encephalopathy associated with abnormal posturing, cerebral oedema, fatty degeneration of viscera, in Japanese children. Reiters syndromeBridge: Shiga toxin by shigella dystentriae type 1 causes HUS Shigella flexneri causes Reiters syndromePlease go through Table viral haemorrhagic fevers in Davidson pg. 230 and make your facts clear.Viral fevers with hepatorenal dysfunction:1. Yellow fever2. Dengue fever3. Ebola fever4. Crimean congo haemorrhagic fever5. Hantaan feverPlasmodium falciparum clinical features :Neuro - Coma, seizure, opisthotonus, cranial nerve palsies CVS - Shock , cardiac failure algid malaria Renal - ARF, haemoglobinuria Liver - Jaundice, hepatitis Resp - Pulmonary edema 