<prompt> The most common site of nasopharyngeal carcinoma isFossa of RosenmullerPalatine tonsilsAntrochoanal regionValleculae  <response>: The commonest site of origin of nasopharyngeal carcinoma is fossa of Rosenmuller in the lateral wall of the nasopharynx.Tumor can spread to the following areas:-Cranium through foramen lacerum ovale cranial nerves involvement III, IV, V, VI; facial pain, and ophthalmic symptoms.Parapharyngeal space cranial nerves IX, X, XI, XII involvement, Horners syndrome, Trismus Pterygoid muscle.Retropharyngeal nodes Neck pain stiffness.Eustachian tube Serous OM.Nose and orbit Obstruction, epistaxis, proptosis.Cervical nodes Upper jugular and posterior triangle nodes enlargement.Distant metastasis Lung, liver, bone.Middle ear Rarely, tumor grows up the tube into the middle ear. 