<prompt> Hirano bodies seen in?RabbiesAlzheimers diseasePicks diseaseViral encephalitis  <response>: Ans. is b i.e., Alzheimers disease Hirano bodies They are intracellular, paracrystalline, eosinophilic structures often occurring as rod shapes in the neurons of individuals with neuro-degenerative diseases including Alzheimers and some forms of Creutzfeldt-Jacob disease. They are intracellular aggregates of actin and actin-associated proteins Most often encountered in neurons of the central nervous system in the neuronal processes in the pyramidal layer in the Sommers sector CA1 of the hippocampus. 