<prompt> Which of the following is true about medullary CA of thyroid -Associated with MET oncogeneElavated levels of Serum calcitoninSeen in MEN I syndromeMost common thyroid cancer  <response>: Ans. is b i.e., Elavated levels of Serum calcitonin o In Medullary carcinoma serum calcitonin is increased, whose function is to lower serum calcium levels. So hypocalcemia may be found associated with MTC. Seen in MEN IIA and B Associated with RET Protooncogeneo MTC secrets not only calcitonin but also some other peptides such as : CEA CGRP Calcitonin gene-related peptide Histaminadases Prostaglandin E2 and F2 Serotonin ACTH may lead to cushing syndrome in about 2 to 4 of pts. 