<prompt> Acetylcholine is not used commercially because:Long duration of actionCostlyrapidly destroyed in the bodyCrosses blood brain barrier  <response>: Ref:KD Tripathi pharmacology 7th edition page.no: 99 ACh is hydrolyzed by the enzyme cholinesterase and choline is recycled. A specific Acetylcholinesterase-AChE or true cholinesterase and a nonspecific Butyrylcholinesterase-BuChE or pseudocholinesterase type of enzyme occur in the body. So Ach is rapidly destroyed in the body 