<prompt> Lactic acidosis is common inMetforminPhenforminRepaglinideRosiglitazone  <response>: Phenformin 247-KDT 689-BB 267-KDT 6th Lactic acidosis more common in Phenformin and rare in Metformin Hypoglycemia is the most common adverse effect with sulphonyl ureas.Repaglinide indicated only in type 2 DM as an alternative to sulfonyl ureas. It should be avoided in liver diseaseRosiglitazone - Thiozolidinediones It is indicated once daily in patients not controlled by metformin alone. It is contraindicated by cardiac or hepatic failure. Weight gain and oedema are the main adverse effects others - headache, myalgia and mild anaemia 