<prompt> In chronic alcoholism the rate limiting component for alcohol metabolism excluding enzymes isare : PGI Dec 2008NADPNADNADPHFADH  <response>: Ans : B NAD C NADPH In chronic alcoholism rate limiting component for alcohol metabolism is NAD NADPHOxidation of ethanol by alcohol dehydrogenaseQ NADQ leads to excess production of NADHSome metabolism of ethanol takes place via a cytochrome P450 dependent microsomal ethanol oxidising systme MEOS Q involving NADPH O2:, This system increase in activity in chronic alcoholism may account for the increased metabolic clearnce in this condition.Ethanol NADPH H O2 MEOS Acetaldehyde 