<prompt> Gastric irritation is least with following NSA1D: PGI June 2008DiclofenacAcetaminophenIbuprofenNaproxen  <response>: Ans. B Acetaminophen Gastric mucosal damageQ: Gastric pain, mucosal erosion ulceration and blood loss are produced by all MSAIDs to varying extents: relative gastric toxicity is a major consideration in the choice of MSAIDs. Paracetamol, a very weak inhibitor of COX is practically free of gastric toxicity and selective misoprosto administered concurrently with NSAIDsanatgonise their gastric toxicity- KDT 6th186Aspirin is acetylsalicylic acid KDT 6th187 