<prompt> Which of the following is not compatible with a diagnosis of juvenile myelomonocytic leukemiaPeripheral blood monocytosis, more than 1 x 109LIncreased hemoglobin F levels for agePresence of bcrabl fusion geneGM-CSF hypersensitivity of myeloid progenitors in vitro  <response>: Juvenile myelomonocytic leukemia JMML is a serious chronic leukemia cancer of the blood that affects children mostly aged 4 and younger. The name JMML now encompasses all diagnoses formerly referred to as juvenile chronic myeloid leukemia JCML, chronic myelomonocytic leukemia of infancy, and infantile monosomy 7 syndrome. The average age of patients at diagnosis is 2 years old. The World Health Organization has included JMML in the category of myelodysplastic and myeloproliferative disordersDiagnosis Edit The following criteria are required in order to diagnose JMML: All 3 of the following: No Philadelphia chromosome or BCRABL fusion gene. Peripheral blood monocytosis 1 x 109L. Less than 20 blasts including promonocytes in the blood and bone marrow blast count is less than 2 on average Two or more of the following criteria: Hemoglobin F increased for age. Immature granulocytes and nucleated red cells in the peripheral blood. White blood cell count 10 x 109L. Clonal chromosomal abnormality e.g., monosomy 7. Granulocyte macrophage colony-stimulating factor GM-CSF hypersensitivity of myeloid progenitors in vitro. These criteria are identified through blood tests and bone marrow tests. Blood tests: A complete blood count CBC will be performed on a child suspected of having JMML and throughout the treatment and recovery of a child diagnosed with JMML. The differential diagnosis list includes infectious diseases like Epstein-Barr virus, cytomegalovirus, human herpesvirus 6, histoplasma, mycobacteria, and toxoplasma, which can produce similar symptoms. 