<prompt> Contraindication to renal biopsy are all EXCEPTBleeding diathesisCRF with normal kidney60 damage of kidney textureUncontrolled hypertension  <response>: CRF with normal kidney 871-CMDT-05 796-97-CMDT-09Indication of renal biopsyContraindication1. Unexplained ARF or CRF2. Acute nephritic syndrome3. Unexplained proteinuria and heamaturia4. Previously identified and treated lesions to plan future therapy5. Systemic disease associated with kidney dysfunction such as SLE, Good pastures syndrome and Wegeners granulomatosis6. Suspected transplant rejection to differentiate it from other causes of ARF7. To guide treatment1. Solitary or ectopic kidney exception transplant allograft2. Horseshoe Kidney3. Uncorrected bleeding disorder4. Severe uncontrolled hypertension5. Renal infection, renal neoplasm6. Hydronephrosis, ESRD7. Congenital anomalies, multiple cysts or uncooperative patients MRI is nearly 100 sensitive and diagnosis of renal artery 96-98 specific for the stenosis 