<prompt> Graves disease; all are true except:Cardiac failure is commonHypertrophy and hyperplasia or thyroid gland is due to TSH-RabRemissions and exacerbations are not infrequentIt is highly vascular with audible bruit  <response>: Clinical FeaturesHyperthyroid symptoms heat intolerance, increased sweating and thirst, weight loss despite adequate caloric intakeSymptoms of adrenergic stimulation palpitations, nervousness, fatigue, emotional liability, hyperkinesis and tremorsMost common GI symptom is increased frequency of bowel movements and diarrhea.Female patients often develop amenorrhea, decreased fertility and increased incidence of miscarriage.Children experience rapid growth with early bone maturation.Older patients present with CVS complications AF and CHF.Overt cardiac failure occurs in only 6-19, increases with ageWeight loss, facial flushing, warm and moist skin, tachycardia, cutaneous vasodilatation, collapsing pulse is seen on examination.A fine tremor, muscle wasting and proximal muscle group weakness with hyperactive tendon reflexes often are present.Overlying bruit or thrill at upper pole due to increased vascularity.Loud venous hum in supraclavicular space.Ophthalmopathy orbital proptosis occurs in 50, dermopathy in 1-2.Dermopathy is characterized by deposition of glycosaminoglycans, leading to thickened skin in pretibial region and dorsum of foot pretibial myxedema 