<prompt> In a patient with nephrotic syndrome and hypoalbuminemia,protein binding of which drug will not be affectedTolbutamideMorphoineDiazepamValproate  <response>: all drugs listed in the optiond are highly plasma protein bound90whereas morphine has only 35 binding to plasma proteins. Moreover ,morphine is a basic drug and binds to alpha1 -acid glycoproteinnot album 