<prompt> A premature infant is born with a patent ductus aeriosus. Its closure can be stimulated by administration ofProstaglandin analogueEstrogenAnti-estrogen compoundsProstaglandin inhibitors  <response>: Before 2 weeks of gestation indomethacin 0.2mgkg dose orally every 12-24 hr for 3 doses. Ref : Ghai essential pediatrics,eighth edition P.no: 419 