<prompt> A child comes with steroid resistant nephrotic syndrome secondary to FSGS, not responsive to methylprednisolone. What next should be givenOral cyclophosphamideOral cyclosporineOral mycophenolateIV cyclophosmaphid  <response>: When child with nephrotic syndrome is restaurant to steroids then calcineurin inhibitors such as cyclosporine and tacrolimus the first drug of choice. Reference: GHAI Essential pediatrics, 8th edition 