<prompt> Antibiotic Prophylaxis for infective endocarditis is indicated in -Isolated secundum ASDMitral valve prolapse without regurgitationPrior coronary artery bypass graftCoarctation of aorta  <response>: Ans. is d i.e., Coarctation of aorta o Coarctation of Aorta is a high risk cardiac lesion for the development of infective endocarditis and an indication for antibiotic prophylaxisPronhvlaxis for infective EndocarditisCardiac lesion for which Endocarditisprophylaxis Advised moderateHieh risk lesionsCardiac lesion for which Endocarditis Dronhvlaxis is not advised Low risk lesionsHigh riskModerate risko Isolated secundum ASDo Prosthetic heart valveso Congenital cardiac malformatins Other than high -low-risk lesions, ventricular septal defect, biscupid aortic valveo Surgically reparied ASD, VSD, PDA without residual defect, 6 months after repairo Prior endocarditiso Comlex cyanotic congenital heart disease; other complex congenital lesion after correction see texto Prior coronary artery bypass grafto Mitral valve prolapse without regurgitation or thickened leafletso Acquired aortic and mitral valve dysfunctiono Physiologic or functional murmuro Prior Kawasaki disease or acute rheumatic fever without valve dysfunctiono Patient ductus arteriosuso Hypetrophic cardiomyopathy asymmetric septal hypertrophyo Coarctation of the aortao Cardiac pacemakers or implanted defibrillatorso Surgically constructed systemic-pulmonary shuntso Mitral valve prolapse with valvular regurgitation andor thickened leaflets 