<prompt> The following antibiotic accentuates the neuromuscular blockade produced by pancuroniumStreptomycinPenicillinChloramphenicolErythromycin  <response>: DRUG INTERACTIONS Antibiotics:- Aminoglycoside antibiotics streptomycin reduce Ach release from prejunctional nerve endings by competing with Ca2. They interfere with mobilization of ACh containing vesicles from a central location to near the terminal membrane, and have a weak stabilizing action on the postjunctional membrane. In clinically used doses, they do not by themselves produce muscle relaxation, but potentiate competitive blockers. Tetracyclines by chelating Ca2, polypeptide antibiotics, clindamycin and lincomycin also synergise with competitive blockers. Ref:- kd tripathi; pg num:-354 