<prompt> LEIGH disease is due to the accumulation ofGlycogenPyridoxineSphingomyelinNone of the above  <response>: A Glycogen L eighs disease or, subacute Necrotizing Encephalopathy Is characterized by an arrest of psychomotor development, feeding problem, seizures, extraocular palsies, and weakness with hypotonia between one and 2 years of age The cardinal Laboratory finding is lactic Addenda Various biochemical abnormalities have been found, all of which lie in the mitrochondrial pathway for converting pyruvate to ATP. 