<prompt> Roths spots are seen in -Infective EndocarditisRheumatic EndocarditisCentral Retinal Arterial Occlusion CRAOTyphoid  <response>: Ans. is a i.e., Infective Endocarditis o Roth s spots lesion are oval retinal haemorrhages with a clear pale center that are typically seen in patients with subacute bacterial endocarditis. They are believed to be caused by immune complex deposition and are included as a minor criteria amongst Duke s criteria for clinical diagnosis of infective Endocarditis.Major clinical manifestation of infective endocarditis Intravascular lesionsImmunological ReactionsSvstemic Manifestationsoccurs due to transmission of microemboli to various organsBacterial infection cause immune complex formationo Fevero Chillso Rigorso Night sweatso Anorexiao Fatigueo Weakness.o Petechiae skin, eye, mucosao Roth spotso Osiers nodeso Janeway lesionso Splinter hemorrhageso Stroke, myocotic aneurysmo Glomerulonephritiso Arthritiso Finger clubbing 