<prompt> Prostaglandin causing fever is:PGF2PGE2PGE1PGT2  <response>: Pyrogenes Substances that cause fever. May be exogenous Bacterial toxins and endogenous IL-1, TNF a, IL-6, Interferons. In the hypothalamus, the prostaglandins, especially PGE2, stimulate the production of neurotransmitters that reset the temperature set point at a higher level. 