<prompt> Gluten-sensitive enteropathy is most strongly associated withHLADQ2BLADR4HLADQ3Blood group B  <response>: Almost all individuals with celiac disease share the major histocompatibility complex II HLA-DQ2 or HLA-DQ8.Gliadin is deamidated by the enzyme transglutaminase and deamidated gliadin peptides bind to DQ2 and DQ8.Recognition of these peptides by CD4 T cells leads to secretion of IFN-γ, which damages the intestinal wall. 