<prompt> Which of the follow ingstatement about atheroscelerosis is true?Intake of polyunsaturated fatty acid is associated with decreased riskThoracic aorta involvement is more severe than abdominal aorta involvementExtent of lesion in veins is same as that in arteriesHypercholesterolemia does not always increase the risk of atherosclerosis perse  <response>: Ans. a. Intake of polyunsaturated fatty acid is associated with decreased risk Med Essentials Kaplan Publishing 2007249; Pan Vascular Medicine by Topal 200290Intake of unsaturated fatty acids PUFA SI UFA is associated with decreased risk of atherosclerosis.Intake of unsaturated fatty acids PUFA MU FAi is associated with decreased risk of atherosclerosis. The maximal benefit is observed with omega-3 polyunsaturated Fatty Acids, howe-er monounsaturated fatty acids also have consistent anti-atherosclerotic benefits and both polyunsaturated fatty acids PUFA and monounsaturated fatty acids MUFA are considered cardioprotective fatty acids. Hyperlipidemia and more specifically hypercholesterolemia is a major risk factor for atherosclerosis. Even in the absence of other factors, hypercholesterolemia is sufficient to stimulate lesion developmentRobbins 8 p497.Atherosclerosis is always severe in areas where pressure and velocity are high as in arteries in contrast to areas where pressure and velocity are low as in veins. Overall atherosclerosis is more severe in high-pressure arteries than in pulmonary arteries with lower blood pressure. It is least severe in veins where pressure and velocity are lowest. Pan - Vascular Medicine by Topol 2002J90Abdominal aorta is more commonly involved than thoracic aorta in atherosclerosis. Within the abdominal aorta lesions tend to be more prominent around the ostia. - Med Essentials Kaplan Publishing 2007249In the systemic circulation severity is accentuated in the abdominal aorta and large arteries of the lower limb where pulse wave reflection and summation effect elevate the pulse and systolic pressures. The disease is more severe in large rather than small vessels indicating the importance of mural tension and Reynolds number both of which are proportional to radius increasing the likelihood and severity of effects of blood flow disturbance at arterial forks, junctions and curvatures- Pan Vascular Medicine by Topal 200290Atherosclerosis: Most heavily vessels involved are abdominal aorta Thoracic aorta Coronary? arteries Popliteal arteries Internal carotid arteries Vessels of circle of Wiilis.Risk factors for AtherosclerosisFirmly establishedRelative Hypercholesterolemia Cigarette smoking Hypertension Diabetes mellitus Advanced age Male gender Hypertriglyceridemia Hyperhomocystenemia Sedentary lifestyle Family history 