<prompt> What are the similarities between fissure in ano and achalasia cardia?Smooth muscle involvementUse of BotoxUse of nitrates calcium channel blockersAll of the above  <response>: Achalasia cardia Fissure in ano - Absence of relaxation of LES - Spasm of internal anal sphincter - LES - Smooth muscle - IAS - Smooth muscle - Nitrates CCBS are used - 0.2 Nitroglycerin; 2 Diltiazem local application - Botox injection - Ach - Relax sphincter -Botox injection - TOC - Laparoscopic Hellers myotomyCircular fibers divided TOC- Notaras lateral sphincterotomy 