<prompt> A patient with Myeloproliferative syndrome presents with decreased while cell count and decreased platelets. The most likely diagnosis is:Chronic myeloid leukemiaMyelofibrosisPolycythemias veraEssential thrombocytosis  <response>: Answer is B Myelofibrosis Myelofibrosis may be associated with decreased white cell count and decreased platlet counts. Myelofibrosis is an established cause for panyctopenia with cellular marrow. Condition WBCount Hematocrit Red cell mass Platelet count Red cell morphology Splenomegaly Philadelphia chromosome CML N N or N Massive Present Myelofibrosis N or or N or or N or Abnormal Massive Absent Polycythemia N or N or N Moderate Massive in late stages Absent Essential Thrombocytosis N or N N Mild Absent 