<prompt> Cell surface molecules involved in peripheral tolerance induction areB7 and CD28CD40 and CD40LCD34 and CD51B7 and CD3  <response>: Immunological tolerance in peripheral lymphoid organs is called as peripheral tolerance. It requires signal to interaction between CD28 and B7. CD28 molecules co-stimulatory molecule bind to their ligands-CD80 B7-l andor CD86 B7-2 and activates T-cell. If the antigen presented by cell do not bear CD28 ligand, a negative signal is delivered and cell become tolerant and anergic. 