<prompt> Mutation that completely disrupts the function of the gene used in which of the following techniques?Knock outNon sense mutationRestriction fragment length polymorphismTargetted gene disruption  <response>: A gene knockout abbretion: KO is a genetic technique in which one of an organism;s genes is made inoperative knocked out of the organism. Also known as knockout organisms or simply knockouts, they are used in learning about a gene that has been sequenced, but which has an unknown or incompletely known function. 