<prompt> A 40 years old patient with liver dysfunction is scheduled for a surgical procedure. Lorazepam can be used for pre-anaesthetic medication in this patient without concern for excessive CNS depression because the drug is:Selective anxiolytic like buspironeConjugated directlyReversible by administration of naloxoneForming several active metabolites  <response>: Ref: Katzung 6e p450 Lorazepam and oxazepam are the benzodiazepines which are excreted from the body by glucuronide conjugation without phase 1 metabolism in the liver. So these can be used safely in hepatic dysfunction. 