<prompt> The major source of estrogen after menopause is?Aromatization of androgens in theca cells of ovaryAromatization of androgens in granulosa cells of the ovaryAromatization of androgens in adipose tissueAdrenal production of estrogens  <response>: Androgen production from the ovary continues beyond menopausal transition caused by sparing of ovarian stroma and theca cells. However due to loss of granulosa cell function, ovary does not contribute to estrogen production by aromatization of androgens. The most impoant source of estrogen is peripheral conversion of androgens produced by ovary and adrenals, principally occurring in adipose tissue. 