<prompt> All are true about Phase II trials except:Safety and efficacyDone in healthy human volunteersTherapeutic exploratory trialPositive evidence in Phase 1 is a prerequisite  <response>: Ans: B Done in healthy human volunteers Ref: Goodman and Gilmans Pharmacological Basis of Therapeutics 12th edExplanation:Phase II trial is done on Patients Phase I done on healthy human volunteersIt is done for assessing the safety and efficacyIf Phase I trial indicates any serious adverse effects. Phase II cannot be donePositive evidence and absence of serious adverse effects from Phase I are prerequisite for proceeding with Phase II trial. See the following table and figure 