<prompt> Marker for granulosa cell tumor :CA 19-9Ca 50InhibinTeratoma  <response>: Ans. is c i.e. lnhibin Granulosa cell Tm 70 of ovarian sex cord cord stromal tumors are granulosa cell tumour. There are 2 clinically and histologically distinct types of Granulosa cell tumor : - The adult form - comprises 95 of cases - The juvenile form - comprises 5 of cases. 50 are diagnosed before pubey Average age being 13 years The clinical features of granulosa cell tumour are due to raised estrogen levels. Adult types : MC presentation is menometorrhagia and post menopausal bleeding. It is aw endometrial hyperplasia, breast tenderness, 2i amenorrhea and adenocarcinoma Juvenile type : MC presentation is irregular bleeding and amenorrhea. Prepubeal girls show isosexual peripheral precocious pubey. 3 Tumour marker : Inhibin A and Inhibin B - They are elevated months before clinical detection of disease and are considered more reliable for postoperative surveillance. Estradiol : It has limited valve in surveillance. Prognosis : Both juvenile and adult type are a low grade malignancy. 95 are unilateral and 80-90 are stage I at the time of diagnosis. 5 year survival rate is 85-95 Remember : In comparison to adult type, the juvenile type is more aggresive and the time to relapse and death is much shoer. 