<prompt> Commonest congenital lesion complicated by infective endocarditis isASDVSDPDATOF  <response>: VSD is the commonest congenital lesion complicated by infective endocarditis. The incidence of infective endocarditis has been estimated as 2100 patients in a follow up of ten years, that is 1500 patient years. The incidence of infective endocarditis is small enough that it is not an indication for operation in small defects. However, it is impoant to emphasize good oral-dental hygiene in all patients with VSD. Reference: Essential Paediatrics; O.P. Ghai; Page no: 417 