<prompt> Endothelial leukocyte interaction during inflammation is mediated bySelectinsIntegrinsDefensinsEndothelin  <response>: Ref Robbins 9e p76 Endothelial leucocytes interaction is also mediated by integrins Integrins are proteins that function mechanically, by attaching the cell cytoskeleton to the extracellular matrix ECM, and biochemically, by sensing whether adhesion has occurred. The integrin family of proteins consists of alpha and beta subtypes, which form transmembrane heterodimers 