<prompt> Rupture of membrane is said to be premature when it occurs at:38 weeks of pregnancy32 weeks of pregnancyPrior to 1st stage of labourII stage of labour  <response>: Premature rupture of membranes PROM is defined as spontaneous rupture of membranes before the onset of labour. Preterm premature rupture of membranes PPROM is defined as premature rupture of membranes before 37 completed weeks. 