<prompt> All are True about hepatorenal syndrome except -Seen in advanced stage of cirrhosisType II has more serious prognosis than type IDue to intense hypoperfusion of kidneyFunctional renal failure without renal pathology  <response>: Hepatorenal syndrome - It is functional renal failure without renal pathology that occurs in about 10 of patients with advanced cirrhosis or acute liver failure. There are marked disturbances in aerial renal circulation in patients with HRS Increase in vascular resistancerenal vasoconstriction accompanied by decrease in systemic vascular resistance . The reason for renal vasoconstriction is multifactorial and poorly understood. It is of two types - HRS1-it is characterized by proggressive impairment in renal function and significant reduction in creatinine clearance within 2 weeks of presentation . HRS2-reduction in GFR and increase in creatinine ,but it is stable and has better outcome than type 1 Currently, patients are treated with midodrine alpha agonist ,octreotide and intravenous albumin. The best therapy for HRS IS liver transplantation.type 1or 2 Ref:Harrison 20 th edition pg no 2413 