<prompt> Irreversible injury in myocardium occurs at -2 minutes30 minutes2 hours5 hours  <response>: Ans-Bo Myocardial function is more sensitive to ischemialoss of contractility occurs within 60 seconds than myocardial structure irreversible injury occurs in 20-40 minutes, thus myocardial necrosis begins at approximately 30 minutes after coronary occlusion.FeatureTimeo Onset of ATP depletiono Loss of contractilityo ATP reduced to 50o ATP reduced to 10o Irrversible injuryo Microvascular injurySeconds 2 minutes10 minutes40 minutes20-40 min 1 hr 