<prompt> All are true statement about Meckels diverticulum except:Occurs in 2 of the populationCommon on antimesenteric borderDiarrhea very commonPeroration occurs  <response>: Meckels diverticulum is situated at the anti-mesenteric border of small intestine.Meckels diverticulum is a true diverticulum as it has all the 3 layers of the intestine.Its the most common congenital anomaly of the gastrointestinal tract.Male to female ratio is 3 : 2.Approximately 60 of Meckels diverticula contain heterotopic mucosa, of which more than 60 consists of gastric mucosa. Second most common ectopic mucosa is that of Pancreas Pancreatic acini. Other mucosa are colonic mucosa, Brunners gland, pancreatic islets, endometriosis and hepatobiliary tissue.A useful but crude Mnemonic used traditionally for describing Meckels diverticula isRule of two : i.e.2 prevalence2 inch in length2 feet proximal to ilcocecal valve.half of these who are symptomatic are younger than 2 yrs of ageMeckels diverticula are asymptomatic. Symptoms arise only when any complication occurs.ComplicationsMost common complicationin children young adults 18 yrs of age bleedingin adults intestinal obstructionoverall bleedingFollowing complications are noted in Meckels diverticulum.Bleedingbleeding in Meckels diverticulum is usually the result of ulceration in ileal mucosa adjacent to the diverticulum caused by the acid secreted by heterotopic gastric mucosa within the diverticulum.Intestinal obstructionIntestinal obstruction associated with Meckels diverticulum can result from several mechanisms.Volvulus of the intestine around the fibrous band attaching the diverticulum to the umbilicusIntussusception with the diverticulum acting as the lead point.Entrapment of intestine by a mesodiverticular band Mesodiverticular band is a remnant of left vitelline artery, it tethers the Meckels diverticulum to the ileal mesentry.Stricture secondary to chronic diverticulitis.Diverticulitisclinical picture is similar to appendicitis.diverticulitis may lead to perforation.Littres hernia - rarely Meckels diverticulum is found in inguinal or femoral hernia. This is known as Littres hernia.Diagnostic studiesMeckels diverticulum in the absence of bleeding can be rarely diagnosed before surgical intervention.Barium meal follow through can rarely demonstrate the diverticulum. Barium enteroclysis can demonstrate the diverticula in 75 of cases but is avoided during acute presentation of complication.If repeated episodes of lower GI bleed occur and an ectopic gastric mucosa in the Meckels diverticulum is suspected, it can be demonstrated by Technetium99 pertechnate radionuclide scan. It demonstrates the ectopic gastric mucosa and localizes the Meckels diverticulum. Angiography can localize the site of bleeding during acute hemorrhage related to meckels diverticula. 