<prompt> A patient of thrombosis if veins has been receiving coumarin therapy for three years. Recently she developed bleeding tendency .how will you reverse the effect of coumarin therapyProtamine injectionVitamin K injectionInfusion of fibrinogenWhole blood transfusion  <response>: Refer KDT 6e p602 Vitamin k is used to reverse bleeding tendancy in warfarin overdose whereas fresh frozen plasma is treatment of choice for bleeding due to warfarin 