<prompt> Factors associated with gallbladder CaChronic cholesteral stoneHyperlipidemiaChronic gall bladder diseaseHepatitis  <response>: Calcification of gallbladder;s associated with cancer in 10-25 cases.90 of gallbladder carcinoma;s associated with gallstones. Risk of developing carcinoma in gallstone disease is 7-10 times more than the general population.Relative risk is less if stone size is less than 2 cm; if stone size is 2-3 cm, it is 2.5; it is 10 or more if stone size is more than 3 cm. Reference: SRB;s manual of surgery,5th edition, page no.659; Bailey Love;s sho practise of surgery,25th edition, page no.1129. 