<prompt> Most common indication for pediatric liver transplant?Wilson diseaseBiliary atresiaNeonatal hepatitisCystic fibrosis  <response>: Ans: b Biliary atresia Ref: Nelson, 18th ed, p. 1712, Table 365-1; 17th ed, p. 1349, Table 349-1Most frequent indication of pediatric liver transplantation is extrahepatic biliary atresia after a failed portoenterostomy Kasai procedure.Causes of neonatal cholestasisIntrahepatic Idiopathic-- Commonest cause Infections-- TORCH, hepatitis, HIV, parvo B19, Reovirus, Bacterial infections esp E. coli. Metabolic amino acid-- TyrosinemiaCHO-- Galactosemia, fructosemia, GSDIVLipid-- Neimann Pick, Gaucher, Wolman Inherited-- a 1 antitrypsin deficiency, cystic fibrosis, neonatal iron storage disease. Endocrine-- Hypopituitarism, hypothyroidism Chromosomal-- Down Edwards syndrome Others-- Zellweger Watson Alagille Byler neonatal lupus histiocytosisExtra hepatic EHB A extra hepatic biliary atresia Choledochal cyst Inspissated bile Sclerosing cholangitis Bile duct stenosis 