<prompt> Enzyme that produces single strand nicks in DNA:DNA polymerase IDNAase IPolynucleotide kinasel - exonuclease  <response>: Deoxyribonuclease I DNAase I Acts on single-stranded DNA, double-stranded DNA, and chromatin. Makes single stranded cuts in nearly any segment of DNA i.e. has low sequence specificity. Digest DNA that is not protectednot bound by protein, into its component deoxynucleotides. Used in DNA Foot Printing. E.g. DNase I nick the single strands of double-stranded DNA. 