<prompt> Most common malignancy that metastasizes to the spine in females is:ThyroidProstateLungBreast  <response>: Metastatic Bone Disease Most common sites of primary for bone metastasis. In males - Prostate Lung In Female - Breast Lung In Children - Neuroblastoma Overall most common is breast Skeletal sites most frequently involved Spine Dorsal Lytic expansile metastasis seen in Renal cancer Thyroid carcinomas Purely Osteoblastic secondaries ProstateCarcinoidMedulloblastoma 