<prompt> Moderate increase in serum aminotransferases with ASTiALT 3 is suggestive ofAcute viral hepatitisProlonged hypotensionAlcoholic liver diseaseDrug hepatotoxicity  <response>: Ans. c Alcoholic liver disease Ref: Harrisons Internal medicine 18thTable 307-2AST, ALTPredictors of alcoholic liver diseaseMild to moderate increaseMarked increaseAST ALT 2:1- suggestive.Fatty Liver pregnancyDrug-induced hepatitisAST ALT 3:1- Highly suggestive.Alcoholic liver diseaseCCFr GTP- Raised in all alcoholicsChronic hepatitisViral hepatitis AcuteALP- Moderate TPOOR PREDICTORS OF ALCOHOLIC HEPATITIS PMN 55,00c mm Discriminant score 32 D.S 4.6 X Prothrombin time control Serum Bilirubin Drug used for treatment: Prednisolone DOC-preferred choice; others-Pentoxiphylline, TNF a InhibitorsLaboratory Diagnosis of Alcoholic Fatty Liver and Alcoholic HepatitisTestCommentASTIncreased two- to sevenfold, 400 UL, greater than ALTALTIncreased two- to sevenfold, 400 ULASTALTUsually 1GGTP maglutamyl transpeptidaseNot specific to alcohol, easily inducible, elevated in all forms of fatty liverBilirubinMay be markedly increased in alcoholic hepatitis despite modest elevation in alkaline phosphatasePolymorphonuclear cellsIf 5500L, predicts severe alcoholic hepatitis when discriminant function 32 