<prompt> Uncommon complication of meckels diveiculum is: September 2005IntussusceptionDiveiculitisMalignancyIncreased bleeding  <response>: Ans. C: Malignancy Epidemiology - More common in males by ratio of 3:2 Lifetime complication rate: 4 - More than 50 of complications occur before age 10 History-Initial repo by Hildanus in 1598, Detailed description by Johann Meckel in 1809 Pathophysiology: Meckels Diveiculum - Incomplete vitelline duct omphalomesenteric closure - Location . Proximal to ileocecal valve by 100 cm Usually within 45 to 60 cm of ileocecal valve Differential Diagnosis of Meckels Diveiculitis-Appendicitis Complications of Meckels Diveiculum - GI Bleeding 25-50 of complications Often associated with ectopic gastric mucosa Hemorrhage is most common presentation under age 2 - Meckels Diveiculitis 10-20 of complications-Similar in presentation to Appendicitis - Bowel Obstruction Volvulus at fibrotic band attached to abdominal wall Intussusception Incarcerated Inguinal Hernia Littres hernia - Other complications-Carcinoid Tumor Radiology - Radionuclide Scintigraphy Sodium Tc-peechnetate Preferential uptake by gastric tissue Most accurate test in Meckels Diveiculum-Test Sensitivity is 85 in children and Test Specificity is 95 in children Less accurate in adults -Cimetidine increases accuracy in adults - Small bowel enema-Indicated for negative scintigraphy in adults - Aeriography indicated for acute hemorrhage 