<prompt> Glomerular basement membrane showing tram-track appearance is seen inMembranoproliferative Glomerulonephritis type 1Membranous nephropathyFocal Segmental GlomerulosclerosisMinimal-Change Disease  <response>: Membranoproliferative Glomerulonephritis MPGN type 1:MPGN is best considered a pattern of immune-mediated injury rather than a specific disease. The glomeruli are large and hypercellular. The glomeruli have an accentuated lobular appearance due to the proliferating mesangial cells and increased mesangial matrix. The GBM is thickened, and often shows a double contour or tram-track appearance, especially evident in silver or PAS stains. This is caused by duplication of the basement membrane also commonly referred to as splitting, usually as the result of new basement membrane synthesis in response to subendothelial deposits of immune complexes.Ref: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 20; The Kidney; Page no: 920 