<prompt> MC cause of death in an adult with PDA isCCFInfective endocarditisRuptureEmbolism  <response>: A most common cause of death in PDA is CCF.A second most common cause of death is infective endocarditis.Course and complications of PDASpontaneous closure of PDA does not usually occur in full-term infants because PDA in term infants results from a structural abnormality of ductal smooth muscles In premature infants spontaneous closure may occur because PDA in these infants results from unresponsiveness to oxygen.Pulmonary vascular pressure regress slower than normal and maximum decrease occurs around 6-8 weeks normally at 1-3 weeks.Common complications are : -CHF MC complication and MC cause of death Infective endocarditisPulmonary hypertension PneumoniaAneurysm of PDA Rare and possible rupture in adult life 