<prompt> An IV drug abuser develops an aggressive form of nephrotic syndrome that does not respond to steroids. A renal biopsy is performed. Which of the following histological diagnoses will most likely be made from the biopsy tissue?Focal segmental glomerulosclerosisIgA nephropathyMembranous glomerulonephritisMembranoproliferative glomerulonephritis  <response>: Focal segmental glomerulosclerosis Associated with IV drug abuse and HIV nephropathy. Aggressive form of nephrotic syndrome Poor prognosis Non responsive to steroid therapy called as collapsing variant. 