<prompt> Familial hypercholesterolemia is due to defect inApo ALipoprotein lipaseApo CApo B 100  <response>: Name Defect Remarks Familial hypercholesterolemia type IIa Defective LDL receptors or mutation in the ligand region of apo B-100 Elevated LDL levels and hypercholesterolemia, resulting in atherosclerosis and coronary disease Reference: Harper; 30th edition; Page no: 275 