<prompt> rtPA is NOT a contraindication in stroke withBP 185110 mm HgHeparin in the past 24 hrsComaLesion occupying 13 of middle cerebral artery territory  <response>: C Coma rtPA Alteplase is indicated in pulmonary embolism, myocardial infarction, and stroke. rtPA therapy in patients with stroke is contraindicated in certain situations like suspicion of subarachnoid hemorrhage on pretreatment evaluation, recent within 3 months intracranial or intraspinal surgery, history of intracranial hemorrhage, uncontrolled hypertension at time of treatment, active internal bleeding, known bleeding diathesis eg, current use of oral anticoagulants, administration of heparin within 48 hours of onset of stroke, platelet count 100,000mm3. 