<prompt> Benzodiazepines differ from barbiturates in the following aspects except:They have a steeper dose response curveThey have higher therapeutic indexThey have lower abuse liabilityThey do not induce microsomal drug metabolizing enzymes  <response>: BENZODIAZEPINES BZDs BZDs produce a lower degree of neuronal depression than barbiturates. They have a high therapeutic index They have lower abuse liability: tolerance is mild, psychological and physical dependence, drug seeking and withdrawal syndrome are less marked BZDs do not alter disposition of other drugs by microsomal enzyme induction A specific BZD antagonist flumazenil is available which can be used in case of poisoning. The slope of the DRC is also impoant. A steep slope indicates that a moderate increase in dose will markedly increase the response dose needs individualization, while a flat one implies that little increase in response will occur over a wide dose range standard doses can be given to most patients. Barbiturates have steep DRC and BZDs have a flat DRCdose response curve. Ref:- kd tripathi;pg num:-55, 401 