<prompt> Which of the following statements about fibromyalgia is true:More common in malesSleep EEG studies have shown disruption in REM sleepIncreased coisol response to stressSPECT studies have reduced blood flow to the thalamus  <response>: Pathogenetic features in fibromyalgia:Disruption of normal stage IV NREM sleepLow levels of serotonin metabolites in CSFReduced levels of growth hormoneIncreased levels of neurotransmitter substance P in CSFDecreased coisol response to stress and coicotrophin-releasing hormoneAutonomic dysfunctionReduced blood flow to the thalamus, caudate nucleus, and tectum on SPECTPsychiatric disturbancesref:Harrisons 18e p2849-2851, 17e p2180 