<prompt> What is the disease in which these hand abnormalities are seen?Down syndromeOsteogenesis imperfectaTurner syndromeMarfan syndrome  <response>: d. Marfan syndromeA - ArachnodactylyB - Steinberg sign thumb tip extends from palm of hand, in a closed fistC - Walker-Murdoch sign thumb 5th finger overlap each other, when opposite wrist is gripped 