<prompt> Which of the following factor is morphogenic as well as mitogenicFibroblast growth factorPlatelets growth factorBone morphogenic proteinInsulin like groth factor  <response>: ref Robbins 9e p19-20 ;8e p87-88 ,fetal and neonatal physiology 4e p867-868 The fibroblast growth factors FGF are a family of cell signalling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development. Any irregularities in their function lead to a range of developmental defects. These growth factors generally act as systemic or locally circulating molecules of extracellular origin that activate cell surface receptors. A defining propey of FGFs is that they bind to heparin and heparan sulfate, thus some of them are found to be sequestered in the extracellular matrix of tissues that contains heparan sulfate proteoglycans and they are released locally upon injury or tissue remodeling Both morphogenic and mitogen 