<prompt> Causes of severe hypokalemic metabolic alkalosis with severe hypeension includeLiddle syndromeBater syndromeGitelman syndromeRenal tubular acidosis  <response>: Liddle syndrome - AD, gain-in-function mutations of ENaC subunits. Activating kidneys to excrete potassium retaining excessive sodium water, leading to hypeension. CF- severe hypeension with hypokalemia, unresponsive to spironolactone yet sensitive to amiloride 