<prompt> When heparin is given in pregnancy, which of the following is to be added?Iron folic acidCopperCalciumZinc  <response>: Ans. is c, i.e. CalciumRef. KDT 6e, p 598, 599; Harrison 17e, p 2400Heparin can lead to osteoporosis, or hypocalcemia so, calcium supplementation is advisable with the use of heparin.Also Know:Durgs which may lead to hypocalcemia and hence calcium supplementation is necessary:CorticosteroidsCyclosporineAnticonvulsantsCytotoxic drugsExcessive alcoholAromatase inhibitorIncrease dose of thyroxineAluminiumGnRHHeparinLithium 