<prompt> Ring sideroblast in myelodysplastic syndrome is associated with which gene mutation?ASXL1EZH 2TET 2SF3B1  <response>: Myelodysplastic syndrome: Group of clonal stem cell disorders characterized by maturation defects, that are associated with ineffective hematopoiesis have high risk of transformation to AML. - Myelodysplastic Syndrome with Ring SideroblasticMDS-RS entity is earlier called as Refractory anemia with Ring Sideroblasts.RA-RSS. - It is diagnosed: Only when 15 of early RBC are Ringed sideroblasts. Also if 5 of early RBC are RS and associated with mutation SF3B1. This mutation is aw better prognosis. 