<prompt> Which of the following causes peripheral neuritis?MethotrexeteVincristineBusulfanCyclophosphamide  <response>: Vincristine oncovin: It is a rapidly acting drug, very useful for inducing remission in childhood acute leukaemia, but is not good for maintenance therapy. Other indications are lymphosarcoma, Hodgkin;s disease, Wilms; tumour, Ewing;s sarcoma and carcinoma lung. Prominent adverse effects are peripheral neuropathy and alopecia. Bone marrow depression is minimal. ESSENTALS OF MEDICAL PHARMACOLOGY K.D.TRIPATHI SIXTH EDITION PAGE NO:825 