<prompt> Hb O2 dissociation curve to left byIncrease pHIncreased PCO2Increased 2.3DPG Exercise  <response>: Oxygen saturation curve Physiology A curve that describes the relationship between Hb O2 saturation and tension; defined by a sigmoid curve which reflects the interaction of the 4 Hb molecules involved in O2 uptake, transpo and release; a ;right shift; of the curve indicates Hb affinity for O2, as occurs in pH-ie,acidosis, temperature, PCO2, while a ;left shift; indicates O2 affinity with pH, temperature, 2,3 DPG and PCO2Right shifts Acidosis, hypehermia, alveolar hypoventilation, anemia Left shifts Alkalosis, hypothermia, hyperventilation, carboxyhemoglobinemia, hypophosphatemia, fetal Hb.Ref: Ganong;s Review of Medical Physiology; 24th edition; page no:642 