<prompt> Mutation in Keratin 1 and 10 are associated with?Epidermolysis bullosa simplexEpidermolytic hyperkeratosisEpidermolytic palmoplantar keratodermaMeesmann epithelial corneal dystrophy  <response>: ANSWER: B Epidermoiytic hyperkeratosisREF: Journal of Pathology 2004; 204: 355-366- DOI: 10.1002path.l643Mutations in keratins K1 and K10 are associated with bullous congenital ichthyosiform erythroderma BCIE, also sometimes referred to as EH or EHK epidermoiytic hyperkeratosis, the principal clinical feature of this disorder Mutations of keratin: Remember at least first 2K5K14Epidermolysis bullosa simplex EBSK1K10Bullous congenital ichthyosiform erythroderma or Epidermoiytic hyperkeratosis EHKK9Epidermoiytic palmoplantar keratodermaK6, K16, and K17Pachyonychia congenitaK3K12Meesmann epithelial corneal dystrophyK413White sponge naevus 