<prompt> Which of the following statements is not true about pancreatic carcinoma?Mutation in p53 gene is associated in 75 of casesHereditary pancreatitis significantly increase the riskMedian survival in locally advanced Stage III disease is 3-6 monthsFive year survival after curative pancreaticoduodenectomy is 20  <response>: Ans. c Median survival in locally advanced stage III disease is 3-6 monthsRef: Sabiston 19e p1541 Following surgical resection and adjuvant therapy for pancreatic cancer, the median survival is approximately 22 months, with 5-year survival of 15 to 20. In the absence of surgical resection, those with locally advanced disease who receive palliative chemotherapy may survive 10 to 12 months, whereas those with metastases rarely survive beyond 6 monthsInoperable cases - survival: Stage 3-10-12 months Stage 4- 6 months 