<prompt> The most impoant determinant of prognosis of a patients with Wilms tumor is:Stage of diseaseHistologyLoss of chromosome 1pAge of presentation  <response>: Most impoant factor for prognosis of Wilms tumor is Histology. Higher the degree of anaplasia - Poorer the prognosis. Presence of anaplasia associated with p53 gene mutation isresponsible for adverse prognosis. 