<prompt> True about Hb dissociation curve:Acidosis shifts O2 dissociation curve to rightIncreased CO2 shifts the curve to leftHypoxia shifts curve to left2,3 DPG has no effect on curve  <response>: Oxygen-hemoglobin dissociation curve is shifted to right in the following conditions: Decrease in partial pressure of oxygen. Increase in partial pressure of carbon dioxide Bohr effect.Increase in hydrogen ion concentration and decrease in pH acidity. Increased body temperature. Excess of 2,3-diphosphoglycerate DPG in RBC. It is also called 2,3-biphosphoglycerate BPG. DPG is a byproduct in Embden-Meyer-hof pathway of carbohydrate metabolism. It combines with β-chains of hemoglobin. In conditions like muscular exercise and in high attitude, the DPG increases in RBC. So, the oxygen-hemoglobin dissociation curve shifts to right to a great extent. 