<prompt> 40 yr old with koilonychias, iron deficiency dysphagia, diagnosis is ?Plummer Vinson syndromeAchalasia cardia7ESNone  <response>: Ans. is a i.e., Plummer Vinson syndrome Plummer-Vinson syndrome Plummer-Vinson syndrome, also known as Brown-Kelly-Paterson syndrome or sederopenic dysphagia, seen in middle aged edentulous women. The plummer Vinsion Paterson Brown Kelly Syndrome is characterized by : - Dysphagia Chronic iron deficiency anemia Atrophic oral mucosa and glossitis Brittle, spoon-shaped fingernails Koilonychia The cause of dysphagia is usually a cervical esophageal web, but abnormal pharyngeal and esophageal motility may play a role. The syndrome characterstically occurs in middle aged edentulous without teeth women. It is a premalignant lesion. Approximately 10 of patient develop squamous cell Ca of esophagus, oral cavity or the hypopharynx. As iron-deficiency anemia is a common finding, it is also known as sideropenic dysphagia. Carcinoma develops in post-cricoid region. 