<prompt> The drug which is used in long term maintenance in opioids addiction: March 2013 hNaloxoneNalorphineButarphanolMethadone  <response>: Ans. D i.e. Methadone Drugs in psychiatry Naltrexone: - Used in opioid dependency: For rapid detoxification Maintenance therapy - To prevent relapse Tolpromate: - Used to reduce craving and - Prevent relapse in heavy alcohol drinking alcohol dependence Lithium: - Therapeutic serum level is 0.6-1.2 mmolL, - Liver is NOT affected in lithium toxicity, ECG changes of lithium toxicity are: Sinus tachycardia bradycardia, Flattenedinveed T waves, AV block and A prolonged QT interval, - Lithium is C I in pregnancy causes CVS defects Drugs used in Maniac Depressive PsychosisMDP: - Lithium, - Valproate, - Carbamazepine, - Levothyroxine Agent of choice for prophylaxis in mania: Lithium mood stabilizer Drug causing depression: - OCP, - Bromocriptine etc. TCA: - Amitryptiline, - Clomipramine etc. Tetracyclic antidepressant: - Maprotiline, - Mianserin etc. SSRI: - Fluoxetine, - Fluoxamine etc. 