<prompt> Use of spironolactone in liver cirrhosis isDecrease edemaImproves liver functionDecrease afterloadDecrease intravascular volume  <response>: Spironolactonealdosterone antagonist - potassium sparing diuretic is staed as a Single dose of 100-200mgday,in cirrhotic patients who have peripheral edema . In moderate ascites, Spironolactone is given along with furosemide . Side effects -gynecomastia is an impoant side effect ,amiloride can be alternatively used in place of Spironolactone. Ref:Harrison 20 th edition pg no 2412 