<prompt> With which of the following of viral hepatitis infection in pregnancy, the material moality is highest -Hepatitis AHepatitis BHepatitis CHepatitis E  <response>: A unique feature of HEV is clinical severity and high case fatality rate of 20-40 percent in pregnant women, especially in last trimester. REF:ANANTHANARAYAN AND PANIKERS TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO:550 