<prompt> All of the following are prion associated disease except:KuruCreutzfeldt-Jacob diseaseAlzheimers diseaseScrapie  <response>: Ans. C. Alzheimers diseasePrionsa. Infectious proteins that cause CNs degenerationb. Prion diseases are disorder of protein conformationc. Reproduce by binding to normal, cellular isoforms of prion protein PrPc stimulating conversion of PrPc into disease causing isoform PrPScd. PrPc -rich in alpha helixe. PrPSc - rich in beta structure.f. Properties: - -devoid of NA- Infectious, genetic or sporadic- Disease result with accumulation of PrPSc PrP gene- PRNP, located on chromosome 20 Most patients present with de mentia and myoclonus Prion diseases:i. Kuruii. Familial fatal insomniaiii. Transmissible Mink Encephalopathyiv. Creutzfeldt- Jacob disease CJDv. Gerstmann- Straussler- Scheinker diseasevi. Scrapievii. Bovine Spongiform Encephalopathy 