<prompt> Which one of the following is not a feature of multiple myeloma -HypercalcemiaAnemiaHyperviscosityElevated alkaline phosphatase  <response>: In multiple myeloma , hypercalcaemia is due to destruction of bone. Anaemia is due to marrow replacement by tumor cells inhibition of hematopoiesis. Hyperviscosity is due to hyperglobulinaemia produce headache,fatigue,visual disturbance hemorrhage.In the absence of fractures , plasma alkaline phosphatase isotope bone scan will be normal despite lytic lesions.Reference : Harsh mohan textbook of pathology 6th edition pg no 383 Davidsons principle practice of medicine 22nd edition pg no1046. 