<prompt> Features of serotonin syndrome associated with SSRI MAOIs are -a Tremorsb Agitationc Cardiovascular collapse d Hypothermiae Suicidal tendencyabcbcacdbcd  <response>: Serotonin syndrome Serotonin syndrome refers to a dangerous and potentially fatal syndrome caused by excess synaptic serotonin levels due to use of serotonin potentiating drugs.This condition is associated confusion, altered consciousness, hyperthermia, tremors, myoclonus, rigidity and hyperreflexia.Drugs causing serotonin syndrome are :-Inhibiting 5-HT metabolism :- MAO inhibitors e.g. tranylcypromine, phenelzine, meclobemide, selegillineInhibit serotonin reuptake SSRIs, TCAs, amphetamine, cocaine, pethidine mepridine,Pentazocin, MDMA, tramadol, Nefazodone, dextromethorphan.Increase 5-HT release :- Amphetamine, cocaine, fenfluramine, MDMA, sibutramine.Serotonin Agonists Buspirone, lithium, LSD, Ergots Dihydroergotamine, triptans Sumitriptan, Piperazine.Other :- ECT, trazodone Nafazodone, Carbamezapine.Clinical features Clinical features of serotonin syndrome are :-, Mental status :- altered consciousness, restlessness, insomnia, elevated mood, coma.Neurological:- Myoclonus, tremor, shivering, rigidity, hyper-reflexia, agitation, incordination, akathesia, mydriasisVital and autonomic:- Fever hyperthermia, sweating, tachycardia palpitation, tachypnea or dysnea, diarrhea, hypertension or hypotension, cardiovascular collapse.TreatmentAggressive cooling and sedation with a benzodiazepine remain the basis of therapy. 