<prompt> Hyperscretory granules seen in with lungCaAdeno CaSmall cell CaLarge cell CaBronchoalveolar Ca  <response>: Small cell carcinoma: Small cell carcinomas are frequently hilar or central in location, have strongrelationship to cigarette smoking and are highly malignant tumours. They are most often associated with ectopichormone production because of the presence of neurosecretory granules in majority of tumour cells whichare similar to those found in argentaffin or Kulchitsky cells normally found in bronchial epithelium. By immunohistochemistry,these tumour cells are positive for neuroendocrine markers: chromogranin, neuron-specific enolase NSE and synaptophysin. 