<prompt> Which of the following is associated with 20 risk of chromosomal anomalies?OmphaloceleGastroschisisCleft lipSpina bifida  <response>: Omphalocele is a midline abdominal wall defect. The abdominal viscera commonly liver and bowel are contained within a sac composed of peritoneum and amnion from which the umbilical cord arises at the apex and center. When the defect is less than 4 cm, it is termed a hernia of the umbilical cord; when greater than 10 cm, it is termed a giant omphalocele. Associated abnormalities occur in 30-70 of infants and include, in descending order of frequency, Chromosomal abnormalities trisomy 13, 18, 21 Congenital hea disease tetralogy of Fallot, atrial septal defect Beckwith-Wiedemann syndrome large-for-gestational-age baby; hyperinsulinism; visceromegaly of kidneys, adrenal glands, and pancreas; macroglossia; hepatorenal tumors; cloacal extrophy Pentalogy of Cantrell Prune belly syndrome absent abdominal wall muscles, genitourinary abnormalities, cryptorchidism Ref: Albanese C.T., Sylvester K.G. 2010. Chapter 43. Pediatric Surgery. In G.M. Dohey Ed, CURRENT Diagnosis Treatment: Surgery, 13e. 