<prompt> In which of the following disease, NAA peak is seen?TuberculomaTumorsCanavans diseaseMeningioma  <response>: Canavan disease, also known as spongiform degeneration of white matter not to be confused with Creutzfeldt-Jakob Disease or aspaoacylase deficiency,is a leukodystrophy clinically characterized by megalencephaly, severe mental and neurological deficits, and blindness. It is an autosomal recessive disorder characterized by a genetic mutation on the sho arm of chromosome 17. There is a deficiency of N-acetylaspaoacylase, a key enzyme in myelin synthesis, with resultant accumulation of N-acetyl aspaate in the brain, CSF, plasma, and urine. MRS Magnetic Resonance Spectroscopy of Canavan Disease shows NAA peak at 2 ppm. Other salient points: Alanine peak is seen at 1.48ppm in meningioma. Lipid lactate peak is seen at 1.33ppm in tuberculoma. 