<prompt> Which of the following drug shows nephrotoxicity during administration?AzathioprineLeflunomideMycophenolate mofetilTacrolimus  <response>: Adverse effects of tacrolimus: Nephrotoxicity Neurotoxicity e.g., tremor, headache, motor disturbances, seizures GI complaints Hypeension Hyperkalemia Hyperglycemia Diabetes The major side effect of azathioprine is bone marrow suppression, including leukopenia common, thrombocytopenia less common, andor anemia uncommon. The principal toxicities of Mycophenolate mofetil are gastrointestinal and hematologic. Leflunomide is hepatotoxic and can cause fetal injury when administered to pregnant women. Ref: Krensky A.M., Bennett W.M., Vincenti F. 2011. Chapter 35. Immunosuppressants, Tolerogens, and Immunostimulants. In L.L. Brunton, B.A. Chabner, B.C. Knollmann Eds, Goodman Gilmans The Pharmacological Basis of Therapeutics, 12e. 