<prompt> Alkalinity of urine is done in -Barbiturate poisoningLithium toxicityAlprazolam overdoseDiazepam toxicity  <response>: Ans. is a i.e., Barbiturate poisoning Alkanization of urine o Acidic drugs are more ionized lipid insoluble polar water soluble at alkaline pH. So, they cannot be absorbed from tubular lumen, i.e. their excretion by kidney is enhanced by alkanization of urine. Such acidic drugs are Barbiturates and Salicylate. o Alkanization of urine is done by i.v. infusion of sodium bicarbonate. 