<prompt> Which among the following is not a feature of follicular lymphoma11, 14 translocationBCL2 over expressionBCL 6 rearrangementCD5 negative  <response>: Ans: a 11,1 4 translocation The hallmark of typical follicular lymphoma is a 14, 18 translocation in 90 cases and not tl 1, 14; 11,14 translocation is a feature of mantle cell lymphoma.More about Follicular lymphoma Usually occurs in middle age male: female 1:1Markers CD 19CD 20CD 10 CALLAsurface Ig -veCD5 -veBCL2 overexpression which is an antagonist of apoptotic cell death. Uncommonly BCL6 gene rearrangement may be seen instead of t 14; 18Usually presents with painless generalized lymphadenopathyInvolvement of extranodal sites is uncommonUsually indolent waxing and waning course with median survival of 7-9 yrs.Treatment:- palliative low dose CT or RT30-50 show transformation to diffuse large B cell lymphoma 