<prompt> What is true about Histoplasmosis -In early stage it is indistinguishable from TBCulture is not diagnosticMycelial forms are infectious formPerson to person spread occurs by droplet infection  <response>: Chronic cavitary histoplasmosis is seen in smokers who have structural lung disease e.g. bullous emphysema is characterized upper-lobe infiltrates, cavitation, and pleural thickening- mimics cavitary tuberculosis.Isolation of fungi by culture and demonstration of dimorphism is diagnostic.Reservoir of infection: SoilMicroconidia spores are the infective form and mode of infection is inhalation.Person to person or animal to man transmission in not known so far for Histoplasmosis. 