<prompt> A 40 year old woman with CIN 2, next step of managementColposcopyCyrotherapyConisationHysterectomy  <response>: Pap Class systemReagen WHO classificationRucha classificationBethesda classificationClass 1Negative for malignantNegativeWithin the normal limitClass 2Inflammationsquamous atypiakoilocytes-Atypical squamous cells of unknown significanceASCUSClass 3Mild dysplasia13rd of the sampleCIN1LSILClass 4Moderate dysplasia13rd to 23rd of sampleSevere dysplasia23rd of sampleCarcinoma insituCIN2,3HSILClass 5Invasive cancerInvasive cancerInvasive cancerPap smear is only a screening test. Any abnormality encountered in it should be confirmed by colposcopic biopsy.Features of abnormal Pap cytologyMosaicismPunctuationsAbnormal dense nucleiGranular cytoplasmIndications for colposcopy biopsyNon-visualization of the transformation zoneObvious fungation in transformation zoneMismatch between colposcopy and pap smearStage IA-1microinvasiveRefer: Shaw;s Textbook of Gynaecology, 15th edition, pg no: 402, 405 