<prompt> The result of increased preload on cardiac muscle is?Lengthening of muscle fibreShortening of muscle fibreNo effectVariable effect  <response>: ANSWER: A Lengthening of muscle fibreREF: Ganongs 22nd edp. 572Preload is determined by amount of blood reaching the heart; it causes an increase in the muscle fiber length and therefore according to frank starlings law increased force of contraction 