<prompt> Howell jolly bodies are seen in?Iron deficiency anemiaHemolytic anemiaPolycythemia veraMultiple myeloma  <response>: Ans. is b i.e. Hemolytic anemia Howell-Jolly bodies HJ bodies These are round solid staining, dark-blue to purple inclusions. They are nuclear remanants predominatly composed of DNA. The presence of Howel-Jolly bodies is associated with hemolytic anemia, megaloblastic anemia, hereditary spherocytosis, myelodysplastic syndrome, post splenectomy and after physiological atrophy of spleen. Although HJ bodies are seen in all these conditions, they are most common after splenectomy. 