<prompt> Alpha feto protein is increased inHepatoblastomaNeuroblastomaSeminomaRenal cell carcinoma  <response>: Alpha fetoprotein AFP is a normal component of plasma protein of the fetus secreted by yolk sac and embryonal hepatocytesfetal liver which usually reduces after bih and persists as a low value level. Normal value is upto 10 ngml. It is an impoant tumour marker for hepatocellular carcinoma 100-1000 ngml. It also increases in non seminomatous testicular tumours, hepatoblastoma and some ovarian tumoursyolk sac tumours. It also increases in benign conditions 100 ngml. It is useful in diagnosing omphalocele, ataxia telengiectasia, neural tube defects. Reference : page 594 SRBs manual of surgery 5th edition 