<prompt> About Ramelteon, which of the following is not true?MT1 and MT2 receptor antagonistMetabolized by Cytochrome p450No significant addictive potentialUseful in long-term treatment of insomnia  <response>: Ramelteon is melatonin receptor agonist, rapidly absorbed and undergoes extensive first-pass metabolism. Ramelteon is a melatonin receptor agonist with both high affinity for melatonin MT1 and MT2 receptors and selec vity over the MT3 receptor. 