<prompt> Now-a-days Down syndrome Is referred to as.Submental disorderOligophreniaMadnessMentally unstable  <response>: Majority of children with Down syndrome function in mild to moderate range of mental retardation. Down syndrome Trisomy 21 - Genetic disorder caused by presence of all or pa of a third copy ofchromosome 21. Typically associated with physical growth delays, characteristic facial features and mild to moderate intellectual disability. REF: DAVIDSONS 21ST ED 