<prompt> Classical markers for Hodgkins disease is?CD 15 and CD 30CD 15 and CD 22CD 15 and CD 20CD 20 and CD 30  <response>: Answer is A CD15 and CD30 The tumor cells in Hodgkins Lymphoma are characteristically positive for CDI5 and CD30 and negative for CD45. Lymphocyte predominance Hodgkins Lymphoma is the only histological subtype that does not express CDI5 and CD30. This subtype expresses CD45 and is often considered as an entirely distinct category from classical Hodgkins disease Harrisons Hodgkins Lymphoma lmmunopheno type Association with EBV Read Sternberg Cell variant Nodular Sclerosis CD15 , CD30 EBV - VeQ Lacunar cellsQ Occasional R-S-cells Mixed cellularity CD15 , CD30 EBV VeQ 70 Classic Reed Sternberg cellsQ Lymphocyte depletion CD15 , CD30 EBV Ve Reticular variant Frequent R-S cells Lymphocyte Predominance CD15 -ye, CD30-ve CD20 ve, CD45ve H17th EBV - Ve Popcorn cell variant 