<prompt> I cells disease is due to defect in:-PeroxisomeMitochondriaLysosomeGolgi apparatus  <response>: I cell disease Inclusion cell disease Pa of the lysosomal storage disease family Defective phosphotransferase uridine-diphosphate-N-acetylglucosamine 1-phosphotransferase an enzyme of the Golgi apparatus Enzyme that phosphorylates mannose residues of glycoproteins to allow their delivery to lysosomes from Golgi Apparatus Features:- Protein targeting disorder Resembles Hurler syndrome Neurological deterioration mucopolysacchariduria is not present,It is not a mucopolysaccharidosis, it is mucolipidosis - glycolipids are accumulated Marked intracellular deficiency of a number of lysosomal hydrolases and elevation of these enzymes in plasma. 