<prompt> A 32-year-old female, asymptomatic, not requiring blood transfusion, presents with Hb 13.0 gmdl. Her HbF levels are 95, HbA2, 1.5. Which of the following is the most likely diagnosis -Hereditary persistence of fetal hemoglobinBeta homozygous thalassemiaThalassemia intermediaBeta heterozygous thalasiemia  <response>: In contrast to alpha thalassemia ,gene deletion rarely ever causes beta thalassemia is only seen in an entity called hereditary persistence of foetal hemoglobin HPFH.In the given case scenario ,HbA2 is within normal limit 1.5-3.5 in contrast to thalassemia where the HbA2 will be increased .Reference :Harsh mohan textbook of pathology sixth edition pg no 322. 