<prompt> Prolapse of veebral disc between L5-S1 will affect which nerve rootL4L5S1S2  <response>: Since most disc herniations occur posterolaterally, the root that gets compressed is actually the root that exits the foramen below the herniated disc. So, a disc protrusion at L4L5 will compress the L5 root, and a protrusion at L5S1 will compress the S1 root . Ref - sciencedirect.com 