<prompt> Deficiency in globin synthesisThalassemiaSickle cell diseaseHereditary spherocytosisNone of these  <response>: Ans. is a i.e., ThalassemiaThalassemia Syndromes :?The thalassemia syndromes are a heterogeneous group of disorders caused by inherited mutations that decrease the synthesis of either the a-globin or 3-globin chains that compose adult hemoglobin, HbA a232, leading to anemia, tissue hypoxia, and red cell hemolysis related to the imbalance in globin chain synthesis. 