<prompt> All of the following drugs are used in treatment of dementia except?MemantineDuloxetineGalantamineDonepezil  <response>: Ans. B. DuloxetineManagement of patient with Dementia:Mini Mental status examination MMSE- score of 24 suggestive of dementia Treat the cause CHOLINESTERASE INHIBITORS: FDA for treatment of AD cholinesterase inhibitors: Tacrine, donepezil, rivastigmine, and galantamine. Reversible inhibitors of enzyme acetylcholinesterase, which degrades ACh in synaptic cleft, thereby increasing availability of intra synaptic ACh. MEMANTINE: noncompetitive NMDA receptor antagonist that may modulate excitatory signaling have neuro- protective actions. FDA approved for use only in moderate to severe AD. Has demonstrated efficacy for both cognitive functional improvements over placebo. 