<prompt> Prepatent period; in lymphatic filariasis is defined as the time interval between inoculation of infective larvae and -Blockage of lymphaticsFirst appearance of detectable microfilariaDevelopment of lymphoedemaDevelopment of adult worm  <response>: lymphatic filariasis:- Pre patent period-Time interval between inoculation of infective larvae and first appearance of detectable microfilaria. Clinical incubation period-Time interval from invasion of infective larva to development of clinical manifestation. 8-16 months. Reference: park;s textbook of preventive and social medicine, 23rd edition, pg no.272 