<prompt> Hirschsprung;s disease is due toLoss of ganglion cells in the sympathetic chainAtrophy of longitudinal musclesFailure of migration of neural crest cells from cranial to caudal directionMalformed teania coli  <response>: . It is a congenital, familial condition, occurring in newborn due to the absence of ganglion cells-- Auerbachs and Meissners plexus in anorectum, which may extend proximally either a pa or full length of the colon. ref:SRB;s manual of surgery,ed 3,pg no 818 