<prompt> Peussis toxin acts by all of the following mechanisms, EXCEPT:ADP ribosylation of proteins associated with receptorsIncrease cyclic AMPIncreased calcium release from sarcoplasmic reticulumActs through G alpha subunit  <response>: Peussis toxin is the major virulence factor of B.peussis. It is an A-B toxin produced from a single operon as an enzymatic subunit 5 binding subunits that are assembled into the complete toxin on the bacterial surface. B subunit binds to the target cells whereas A subunit acts on the target. The binding subunits mediate attachment of the toxin to the carbohydrate moieties on the host cell surface. The enzymatic subunit is then internalised ADP- ribosylates a G protein that affects adenylate Cyclase activity. Unlike cholera toxin, which in essence keep cyclase activity turned on peussis toxin freezes the opposite side of the regulatory circuit cripples the capacity of the host cell to inactivate cyclase activity. Multiple Intracellular signalling pathways are disrupted by this G protein modification. Among the results of this action are lymphocytosis, insulinemia histamine sensitisation. Ref: Ray C.G., Ryan K.J. 2010. Chapter 31. Haemophilus and Bordetella. In C.G. Ray, K.J. Ryan Eds, Sherris Medical Microbiology, 5e. 