<prompt> Which of the antiglaucoma drug is contra- indicated in sulfonamide hypersensitivity -p-blockersPilocarpineAcetazolamideProstaglandin analogues  <response>: Ans. is c i.e., Acetazolamide o Carbonic anhydrase inhibitors acetazolamide are contraindicated in sulfonamide hypersensitivityImportant contraindications of topical agents of POAGo b-blockers non-selective :-Asthma, COPD, CHF, sinus bradycardia, AV blocko Cholinomimetic Pilocarpine :- Uveitiso Sympathomimetic agents Dipiveferine :- Angle closure glaucoma, cardiovascular disease. Brimonidine, Apraclonidine :- Use of MAO inhibitors, hypertensive crisis, Parkinsonism.o Carbonic anhydrase inhibitors :- Hypersensitivity to sulfonamide, eye injury.o Prostaglandin analogues :- Ocular inflammation or infection. 