<prompt> A 48-year-old lady presented with hepatosplenomegaly with pancytopenia. On bone marrow examination, a tissue paper crumpled appearance is seen. Which is the most likely product to have accumulated?GlucocerebrosideSphingomylinSulfatideGanglioside  <response>: Ans. a GlucocerebrosideRef: R 9thpg 151; 8thpg 151The clinical feature and bone marrow feature is typical of Gauchers disease. This results due to accumulation of cerebroside Q inside mononuclear phagocytic cells due to deficiency of b-glucocerebrosidase. 