<prompt> Decreased erythropoietin levels are seen in:End stage renal diseaseHeart failurePolycytic kidney diseaseAdvanced Liver failure  <response>: Ans: A End stage renal disease Ref: Harrisons Principles of Internal Medicine, 18th ed.Explanation:End-stage renal disease is replaced by the term stage 5 CKD Chronic kidney disease.The primary cause in patients with CKD is insufficient production of erythropoietin EPO by the diseased kidneys Ref: Harrison.Causes of Anemia in CKDRelative deficiency of erythropoietinDiminished red blood cell survivalBleeding diathesisIron deficiencyHyperparathvroidismbone marrow fibrosisChronic inflammationFolate or vitamin B12 deficiencyHemoglobinopathyComorbid disease 