<prompt> Red man syndrome is due to:VancomycinPolymyxinRifampicinTeicoplanin  <response>: Vancomycin has the potential to release histamine by direct action on mast cells. Rapid i.v. injection has caused chills, fever, urticaria and intense flushing-called Red man syndrome.Reference: Essentials of Medical Pharmacology Eighth Edition KD TRIPATHI page no 806 