<prompt> Home to bilirubin conversion is carried out byHeme oxygenaseHeme reductaseHeme isomeraseHeme hydrolase  <response>: Within the macrophage, heme derived from haemoglobin is broken down by heme oxygenase, conveing it to biliverdin Carbon monoxide and iron arereleased as by-productsReference: Harper biochemistry 30th edition page no 672 