<prompt> Von Recklinghausen disease is associated with:GlaucomaOptic nerve gliomaNeurofibroma of the lidsAll the above  <response>: Ans. d All the aboveRef: Kanski 7e, p. 854; Yanoff 2e, p. 1098NF-1 is the most common phakomatosis. It is Autosomal Dominant AD.Ocular features Orbital Optic nerve glioma Spheno-orbita encephalocoele Eyelid - Ipsilateral plexiform neurofibroma Glaucoma - unilateral and congenital Iris lesions Lisch nodules Hamartomas Ectropion uveae Prominent corneal nerves Choroidal nevi Posterior subcapsular cataractNF1 Von Recklinghausen diseaseDiagnostic Criteria - 2 or more should be present 6 cafe-au-lait macules Freckling Axillary or inguinal - Pathognomonic2 neurofibromas any or 1 plexiform neurofibroma it involves the eyelid, gives the characteristic S- shaped deformity Optic glioma Osseous lesion such as sphenoid dysplasia2 Lisch Nodules First degree relative with NF1,Mnemonic: CAN GOLF 