<prompt> Which of the following features cannot be used to differentiate between Hodgkins and Non Hodgkins Lymphoma ?Extranodal involvementSpread contiguityPainless lymphadenopathyLocalisation to a particular group of lymph nodes  <response>: Hodgkin lymphoma, like NHL, usually manifests as painless lymphadenopathy. Although a definitive distinction from NHL can be made only by examination of a tissue biopsy, several clinical features favor the diagnosis of Hodgkin lymphoma. After the diagnosis is established, staging is used to guide therapy and determine prognosis. 