<prompt> All are impoant mechanisms in the formation of lithogenic bile:Increased biliary secretion of cholesterolIncreased activity of HMG CoA reductaseClofibrateLow calorie and cholesterol rich diet  <response>: Mechanisms in the formation of lithogenic stone-forming bile. The most impoant is increased biliary secretion of cholesterol. This may occur in association with obesity, the metabolic syndrome, high-caloric and cholesterol-rich diets, or drugs e.g., clofibrate and may result from increased activity of hydroxymethylglutaryl-coenzyme A HMG-CoA reductase. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2617 