<prompt> Conversion of glucose to glucose-6 phosphate in human liver is byHexokinase onlyGlucokinase onlyHexokinase and glucokinaseGlucose-6-phosphate dehydrogenase  <response>: Hexokinase and glucokinase may be considered as iso-enzymes. Glucokinase is under the influence of insulin; but hexokinase is not. Hexokinase is present in most tissues. Glucokinase with a high Km for glucose is present in liver and beta cells. Glucokinase is induced by insulin.Reference: Vasudevan 7th ed, pg 109 