<prompt> Orange urine and tears are adverse effect ofRifampicinIsoniazidEthambutolPyrazinamide  <response>: A. i.e. Rifampicin 742- KDT6th 398- Lipincotts 3rd Urine of patients taking Nitrofurantoin becomes dark brown due to its metabolites Systemic administration of phenol gives - green colour to urineDrugAdverse- effectsCommentsEthambutolOptic neuritis with blurred vision, red- green color blindnessEstablish baseline visual acuity and color vision test monthlyIsoniazidHepatic enzyme elevation, hepatitis, peripheral neuropathy Take base line LFT measurement Clinically significant interaction with phenytoin and anifungal agents azolsPyrazinamideNausea, hepatitis, hyperuricemia, rash joint ache, gout rareTake base line LFT and uric acid measurementRifampinHepatitis, GI upset, flue- like syndrome,Take baseline LFT and CBC count, Warn patients that urine and tears may turn red- orange in colorStreptomycinOtotoxicity, nephrotoxicityDo base line audiography and renal function tests Red Mans Syndrome is caused by vancomycin Fever, Urticaria and Intense flushing 