<prompt> Which of the following is the mechanism of action of local anaesthetics?Block Na channelBlock K channelOpen Na channelBlock Ca channel  <response>: Local anaesthetics block the conduction of action potential by blocking voltage gated Na channels. Ref: Medical Pharmacology at a Glance By Michael J. Neal 4e, Page 15 ; Instant Pharmacology By Kourosh Saeb Parsy, Ravi G, Assomul, Fakkar J. Khan, Kasra Saeb Parsy, Eamonn Kelly; Page 123 