<prompt> The primary form of cortisol in the plasma is that which is:Bound to albuminBound to transthyretinFree in solutionBound to corticosteroid-binding globulin CBG  <response>: Ans. D. Bound to corticosteroid-binding globulin CBGCortisol, like other steroid hormones, is carried in the blood largely bound to carrier proteins, although a small percentage exists free in solution. The majority of cortisol is bound to a specific carrier protein, corticosteroid-binding globulin CBG, while smaller amounts are bound nonspecifically to albumin. Few, if any, cortisol receptors would be expected in the plasma and transthyretin binds primarily thyroxine. 