<prompt> In pregnancy what is the dose of folic acid in mcgday100200400800  <response>: Ans. c 400 Ref. Williams Obstetrics 22ndCh. 8 In nonpregnant women, folic acid requirement is 50 to 100 mgday. During pregnancy, requirements are , and 400 mgday are recommended.FOLIC ACID DEMAND IN PREGNANCY The earliest biochemical evidence is low plasma folic acid concentrations. The earliest morphological evidence is hypersegmentation of neutrophils, and newly formed RBCs are macrocytic. Rx:- folic acid, a nutritious diet, and iron.- As little as 1 mg of folic acid administered orally once daily produces a striking hematological response.- By 4 to 7 days after beginning Rx, the reticulocyte count is -, leukopenia and thrombocytopenia are corrected. 