<prompt> Cholera toxin effects are mediated by stimulation of which of the following second messengerscAMPcGMPCa44 -calmodulimIP3 DAG  <response>: Ans. is a i.e., cAMP . Effects of cholera toxin enterotoxin are mediated by activation of adenylate cyclase which produces elevated levels of intracellular cAMP. Elevated levels of cAMP inturn cause an ouylowing of ions and water to the lumen of intestine producing watery diarrhea. 