<prompt> Which one of the following clinical signs is not seen in ophthalmic Gravesdisease?Lid retractionFrequent blinkingPoor convergenceUpper lid lag on down gaze  <response>: Manifestations of Graves disease:1.Diffuse hyperfunctioning goiterbruit over gland.2. Graves ophthalmopathyinflammatory infiltrate of orbital contents, exclusive of globe, with lymphocytes, mastcells, and plasma cells.It has two componentsa spasticstare, lid lag, lid retraction,b mechanicalproptosis, ophthalmoplegia, congestiveoculopathy chemosis, conjunctivitis, periorbital swelling, corneal ulceration, optic neuritis, optic atrophy.Dermatopathythickening of dermis, which is infiltrated with lymphocytes and with hydrophilic, metachromatically staining mucopolysaccharides. Dermatopathy usually occurs over dorsum of legs or feet localized or pretibial myxedema. It is a late phenomenon but not a manifestation of hypothyroidism,skinthickened, Peau dorange appearance, pruritic, hyperpigmented, nonpitting edema, and thyroid acropathy clubbing of fingers and toes with bony changes may accompany the dermal changes. 