<prompt> Patient with NTD, dose of folic acid in next pregnancy -0.5 mg1 mg2 mg4 mg  <response>: Ans. is d i.e., 4mg o The recurrence risk of neural tube defect is: 3 - 5 if a couple has previously had a child with either anencephaly or spina bifida. 5 if either parent was bom with a NTD 10 if a couple has two affected children.o Folic acid supplementation 4 mg daily 1 month before conception to about 12 weeks of pregnancy. 