<prompt> False about PSCPSC in UC, the association is 30Low incidence of cholangitisIncreased incidence of colonic carcinoma in PSCUCDespite the presence of diffuse disease, hepatic duct bifurcation is most severely structured segment  <response>: Primary sclerosing cholangitis PSC is a cholestatic liver disease characterized by fibrotic strictures involving intrahepatic and extrahepatic biliary tree in the absence of a known precipitating cause More common in HLA B8DR3 Incidence of UC in PSC ranges from 75-80 PSC is present in 5.5 of patients with chronic UC Ref: Sabiston 20th edition Pgno :1508-1509 