<prompt> MRP 2 and conjugated hyperbilirubinemia associated with which of the following?Criggler Najjar syndrome type ICriggler Najjar syndrome type IIDubin Johnson syndromeRotor syndrome  <response>: Dubin-Johnson Syndrome:- Defect in canalicular protein called MRP2 leading to increase in conjugated bilirubin CB. Criggler Najjar Syndrome type I and type II has decrease activity of UDP-glucuronodyltransferases leading to increase unconjugated bilirubin UCB which enters CNS and can cause kernicterus. 