<prompt> A woman of age 34 yrs has been taking large quantities of vitamins in hope that it would prevent many infections cancers. Now she came with complaint of sleep disturbances, increased hair fall, anorexia, nausea, fissures dryness of lips. What is the most likely cause of these symptoms?Chronic Vitamin A toxicityChronic Vitamin K toxicityChronic Vitamin E toxicityChronic Vitamin D toxicity  <response>: Only fat-soluble vitamins can cause toxicity as they can be stored in the body. Given clinical features - sleep disturbances, hair loss, anorexia, nausea, skin desquamation are suggestive of Vitamin-A toxicity. Enlarged liver papilloedema can also be seen in chronic Vit-A intoxication. High doses are teratogenic. Vitamin-D toxicity can cause hypercalcemia which results in anorexia, nausea, vomiting, thirst drowsiness. The patient may lapse into coma, while cardiac arrhythmias renal failure may occur. 