<prompt> Which of the following actions is ascribed to delta type of opioid receptors -Supraspinal analgesiaRespiratory depressionEuphoriaReduced intestinal motility  <response>: Ans. is a i.e., Supraspinal analgesia Mu o Analgesia spinal supraspinal o Respiratory depression o Euphoria Reduced G1 motility Sedation Miosis Physical dependence Increased feeding 1c Kappa Analgesia spinal Supraspinal Respiratory depression lower ceiling Dysphoria o Reduced GI motility Sedation Diuresis Increased feeding Psychomimetic effects S Delta Analgesia spinal Supraspinal Modulation of GH DA release Increased feeding a sigma receptor nonpioid receptor mediates naloxone insensitive effects of pentazocine, e.g., dysphoria, psychomimetic action, tachycardia and mydriasis. Remember o Psychomimetic effects hallucinations, anixety and night mares of agonist-antagonists nalbuphine, dezocine are due to K receptors. o Ceain endogenous peptides endrophins, enkephalins and dynorphins act on these opioid receptors and produce analgesia. o A new endogenous peptide nociception has been isolated which acts on orphanin like receptors ORLs or nociceptionorphanin fQ NoFQ receptors. o Endorphins have major action on receptors. o Enkephalins have major action on 6 receptors. o Dynorphins have major action on x receptors. 