<prompt> Most serious injury to eye is caused by:Nitric acidHydrochloric acidSulphiric acidLime  <response>: Ans: d Lime Ref: AK Khurana, 4th ed, p. 414In general the serious chemical bums are caused by alkalies acids of which more serious ones are alkali bums. Alkali bumsAcid bumsAgentLime, caustic soda, caustic potashLiquid ammonia most harmfulSulphuric acid, citric acid, hydrochloric acidMechanismSaponification of fatty acids in the cell membraneExtract water - total necrosisSoftening gelatinizationAll result in increased penetration into tissuesCoagulation of all the proteins which then act as barriers prevent deeper penetration of acids into tissuesRxImmediate thorough washThen weak acids eg. Boric acid neutralizationImmediate thorough washThen weak alkalisodiumcarbonate neutralization 