<prompt> Tumor suppressor genes BRCA1 and BRCA1 prevent tumorigenesis by acting asInhibitors of mitogenic signaling pathwaysInhibitors of ceil cycle progressionInhibitors of Invasion and MetastasisDNA repair factors  <response>: Answer: d DNA repair factors ROBBINS 9th ED, P-291Tumor suppressor geneFamilial syndromesSporadic cancers Inhibitors of mitogenic signaling pothwaysAPCFamilial colonic polyps and carcinomasCarcinomas of stomach, colon, pancreas melanomaNF1Neurofibromatosis type 1Neuroblastomas juvenile myeloid leukemiaNF2Neurofibromatosis type 2 Acoustic schwannomas, MeningiomasSchwannomas MeningiomasPTCH PatchedGorlin syndrome basal cell carcinoma, medulloblastomaBasal cell carcinoma MedulloblastomaPTEN Phosphatase and tensinCowden syndromeMany carcinomas and lymphoid tumorsSMAD2, SMAD4Juvenile polyposis syndromeColon and pancreatic cancerInhibitors of cell cycle progressionRBFamilial Retinoblastoma syndromeRetinoblastoma, Osteosarcoma Ca of breast, colon, lungCDKN2AFamilial melanomaPancreatic, breast, and esophageal carcinoma, melanoma Inhibitors of Pro-growth Programs of Metabolism and AngiogenesisVHLVHL syndromeRenal cell carcinomaSTK11Peutz-Jeghers syndromeVariety of cancersSDHB, SDHDFamilial paraganglioma Familial pheochromocytomaParagangliomaInhibitors of Invasion and MetastasisCDH1 E-cadherinFamilial gastric cancerGastric cancer, Lobular breast cancerEnablers of Genomic StabilityTP53 p53Li-Fraumeni syndromeMost human cancers DNA Repair Factors BRCA1Familial breast and ovarian carcinoma; carcinomas of male breast; but lower than BRCA2, Cancers of prostate, pancreas, fallopian tubeRareBRCA2Familial breast and ovarian carcinoma chronic lymphocytic leukemia male breast cancer, cancer of prostate, pancreas, stomach, gallbladder, bile duct, pharynx, melanoma,RareMSH2, MLH1, MSH6HNPCCColon and endometrial cancer Unknown mechanisms WT1Wilms tumorWilms tumorMEN 1Multiple endocrine neoplasia 1Pituitary, pancreatic, parathyroid tumors 