<prompt> Best treatment for Sickle cell anemia is?HydroxyureaSulphonamideIron InjectionBlood transfusion  <response>: - Hydroxyurea increases HbF levels - used for treatment of sickle cell anemia. Management of Sickle cell anemia: Avoid infections prompt correction of any inflammation Pneumococcal HIB vaccination early in life Acute painful crisis - vigorous hydration analgesia Bone marrow transplantation, gene therapy Hydroxyurea for patients with severe symptoms 