<prompt> A patient on anti-psychotic drugs develops temperature of 104degC, BP about 150100 and abnormal behavior. What is the likely diagnosis?Aggravation of psychosisParkinsonismDystoniaNeuroleptic malignant syndrome  <response>: Neuroleptic malignant syndrome is characterized by immobility, rigidity, tremors, fever, dysphagia, stupor or coma with autonomic effects like fluctuating BP and HR. It could be due to sudden reduction in dopaminergic or cholinergic action. Ref KD Tripati 8thh ed. 