<prompt> A child with nephrotic syndrome developed anasarca. The main cause of edema in nephrotic syndrome is:Na and water retentionIncreased venous pressureDecreased plasma proteinsHyperlipidemia  <response>: Nephrotic syndrome: Nephrotic syndrome consists of the following: Urine protein excretion 3 g per 24 hours Hypoalbuminemia albumin 3 gdL Peripheral edema Hyperlipidemia Oval fat bodies in the urine Peripheral edema is a hallmark of the nephrotic syndrome, occurring when the serum albumin concentration is 3 gdL 30 gL. Edema is most likely due to sodium retention and, at albumin levels 2 gdL 20 gL, aerial underfilling from low plasma oncotic pressure. Ref: Watnick S., Dirkx T. 2013. Chapter 22. Kidney Disease. In M.A. Papadakis, S.J. McPhee, M.W. Rabow Eds, CURRENT Medical Diagnosis Treatment 2013. 