<prompt> Signs and symptoms of uncomplicated pituitary diabetes insipidus can be controlled using -MannitolGlycerolDesmopressinEthyleneglycol  <response>: Ans. is c i.e., Desmopressin Treatment of diabetes insipidus The signs and symptoms of uncomplicated pituitary DI can be eliminated completely by treatment with desmopressin DDAVP, a synthetic analogue of A VP. DDAVP acts selectively at V 2 receptors to increase urine concentration and decrease urine flow in a dose-dependent manner. It is also more resistant to degradation than is AVP and has a three- to fourfold longer duration of action. Desmopressin can be given by IV or SC injection, nasal inhalation, or oral tablet. The doses required to control pituitary DI completely vary widely, depending on the patient and the route of administration. 