<prompt> Mechanism of action of theophylline in Bronchial asthma include all of the following Except ?Phosphodiesterase inhibitionAdenosine receptor antagonismIncreased histone deacetylationBeta-2 receptor stimulation  <response>: Ans. is d i.e., Beta-2 receptor stimulation Proposed mechanisms of action of theophylline Phosphodiesterase inhibition Non selective Adenosine receptor antagonism A1, A2 Increased histone Deacetylase activity red efficacy of coicosteroids Inhibition of intracellular calcium release Stimulation of catecholamine release Inhibition of NF - alpha Beta translocation into the nucleus nuclear translocation Mediator inhibition Prostaglandins, TNF alpha 