<prompt> Which of the following drug is second generation antihistaminic:PromethazineLoratadineDiphenhydramineDoxylamine  <response>: Ans. B. LoratadineSecond generation antihistaminic drug dont enter the CNS, no anticholinergic side-effects, drugs are cetirizine, levocetirizine, loratadine, ebastine, azelastine. 