<prompt> Mucopolysaccharidoses are caused byAn increased rate of synthesis of proteoglycansDefects in the degradation of proteoglycansThe synthesis of polysaccharides with an altered structureAn insufficient amount of proteolytic enzymes  <response>: Mucopolysaccharides are excreted in urine in abnormal amounts in the group of lysosomal storage disorders known as mucopolysaccharidoses. They can be detected by 2D gel electrophoresis techniques; some mucopolysaccharides can also be detected by simple urine screening tests like CPC test, Cetavlon test and Alcian blue staining.Ref: D M Vasudevan 7th edition Page no: 80 