<prompt> Extent of nicotinic receptor blockade required for neuromuscular transmission failure due to non-depolarizing neuromuscular blockers:-5About 20About 3080 - 90  <response>: Non depolarising neuromuscular blocker are competitive blockers and when more than 80 -90 receptor is blocked then only neuromuscular transmission fails. Characteristic of NDNB 1. Decreased twitch response to a simple stimulus. 2. Fade on tetanic stimulus 3. Train of four response is seen 4. TOF ratio 1 5. Post tetanic potentiation 6. Potentiation of other nondepolarising drugs Antagonism by anticholinesterase 