<prompt> Pyridoxine is given with which antitubcrcular drug?RifampicinINHPyrazinamideEthambutol  <response>: B INH INH isoniazid causes peripheral neuritis and can be prevented by pyridaxine B6 Peripheral neuropathy associated with isoniazid occurs in up to 2 of patients given 5 mgkg. Isoniazid appears to interfere with pyridoxine vitamin B6 metabolism. Risk of isoniazid-related neurotoxicity is greatest for patients with preexisting disorders that also pose a risk of neuropathy, such as HIV infection; for those with diabetes mellitus, alcohol abuse, or malnutrition; for those simultaneously receiving other potentially neuropathic medications, such as stavudine. These patients should be given prophylactic pyridoxine 25-50 mqdDrugSide effectsManagementIsoniazidHepatitisMonitor ASTlimit alcohol consumptionmonitor for hepatitis symptomseducate patient stop drug at first symptoms of hepatitis nausea, vomiting, anorexia, flulike syndrome Peripheral neuritisAdminister vitamin B6 Optic neuritisAdminister vitamin B6stop drug SeizuresAdminister vitamin B6 