<prompt> B6. Following is not true about the gene mutations leading to breast carcinomaMost common mutation in inherited breast carcinoma is BRCA1BRCA 1 mutation is present in most of the cases of breast carcinomaInherited breast carcinomas make about 3 of the total casesp53 mutation also increases chances of colon and brain cancer  <response>: Ans. b BRCA 1 mutation is present in most of the cases of breast carcinomaRef: Robbins 9thpg 1054; 8thpg 1077a. Most common gene involved in familial breast cancer-BRCA152 BRCA132b. p53 mutation is present in most of the cases of breast carcinomac. Inherited breast carcinomas make about 3 of the total casesd. p53 mutation increases risk of all cancers 