<prompt> A Young boy presents with multiple flaccid bullous lesions over trunk with some oral mucosal lesions. Most likely finding on immunofluorescence study of the biopsy specimen would be:Fishnet IgG deposits in epidermisLinear IgG in DepositsLinear IgA in dermal papillaeGranular IgA in reticular dermis  <response>: Ans. A. Fishnet IgG deposits in epidermis Pemphigus vulgarisBullous PemphigoidAutoantibodies againstDesmosomal proteinsHemidesmosomal proteinsAge40-60 yrs60-75 yrsInitial siteOral mucosaLower extremitiesBullaeFlaccidTensePruritusMild-Nonexistent or severeNikolskys sign-Mucosal involvementin almost all patients- 10-40 onlyHPESuprabasal acantholytic blisters Tombstone appearanceSubepidermal blisterseosinophil rich dermal infiltrateDIFIgG C3 deposits at intercellular substance of epidermis Fishnet appearanceIgG, C3, and IgAIgM at BM zone.IIFCirculating IgG antibodies to intercellular substance of epidermis.Anti-BM zone antibodies IgGRxQSteroids immunosuppressantsDapsoneGoldSteroidsImmunosuppressantsDapsonePost inflammatory Hyperpigmentation- 