<prompt> Concerning fibroidsUse of GnRH analogues cause permanent reduction in sizePregnancy following myomectomy is about 80Recurrence rate following myomectomy is about 20Growth factors IGF-L EGF stimulates myoma to grow  <response>: EGF, IGF-1, TGF stimulates the growth of leiomyoma either directly or estrogen GnRH analogues reduces 50-80 of myoma size when used for 6months Pregnancy rate following myomectomy is 40-60 Recurrence and persistance following myomectomy is 30-50 D.C.DUTTAS TEXTBOOK OF GYNECOLOGY,Pg no:272,281,282,6th edition Intramural fibroid : endometrial sampling next step of management 