<prompt> Fructose intolerance is due to deficiency of:FructokinaseAldolase-BFructose 1,6 bisphosphataseFructose synthase  <response>: Ans: b Aldolase - B Ref: Vasudevan, 4th ed, p. 120Hereditary fructose intolerance is due to defect in the enzyme Aldolase-B.Hereditary fructose intolerance:Defect: Aldolase-B enzyme deficiency fructose 1 PO4 aldolase activity.Lethargy, vomiting, diarrhoea, hypoglycaemia.Liver damage, hyper bilirubinaemia deposition of fructose 1 PO4 in liver and kidney.Hyper uricaemia, lactic acidosis.Renal proximal tubular defect fanconi.Cataract is not a feature of this disease, because fructose is not an Aldose sugar and therefore not a substrate for aldose reductase in the lens.Treatment - Eliminate fructose from diet.Fructokinase deficiency is usually asymptomatic. 