<prompt> What is the leading cause of adrenal insufficiency?Autoimmune adrenalitisTB of adrenalsX- linked Adreno leukodystrophyHypothalamic pituitary disease  <response>: This is a closely worded question Please note that incidence of Secondary adrenal insufficiency is MORE common than primary adrenal insufficiency. The most common cause of secondary adrenal insufficiency is hypothalamic pituitary insufficiency. Most common cause of primary adrenal insufficiency is Autoimmune Adrenalitis. 