<prompt> Patient with persistent diarrhea hypotension. Diagnosis -VIPomaACTHomaGRFomaGlucagnoma  <response>: Ans. is a i.e., VIPoma Pancreatic Neuroendocrine TumorsTumourBiologicaly active peptide secretedTumour locationMalignant percentageMain symptoms and signsGastrinoma non b cell tumourGastrinDuodenum 70 Pancreas 25 other sites 560-90o Pain 79-J 00o Diarrhoea 30-73o GERD 30-35o Peptic ulcerInsulinoma b cell tumourInsulinPancreas 99 Insulinomas are distributed equally on head body and tail of pancrease 10o Symptoms of hypoglycemiao Symptoms releive on administration of glucoseVIPOMA Verner-Morrison syndrome, pancreatic cholera WDHAVasoactive intestinal peptidePancreas 9040-70o Watery diarrhoea 90-100o Hypokalemia 80-100o Hypochlorhydriao Dehydration 83GlucagonomaGlucagonPancreas 100 usually occurs singly in pancreatic tail50-80o Dermatitis migratory necrolytic erythema 67-90o Glucose intolerance 40-90o Weight loss 66 to 96o .Anemia33-85o Diarrhoea 15-29o Thromboembolism 