<prompt> Malignancy in a multinodular goiter is most often:-Follicular carcinomaPapillary carcinomaAnaplastic carcinomaMedullary carcinoma  <response>: Follicular ca: - Seen in iodine deficient areas - MC malignancy in long standing goiter - Mc malignancy in multinodular goiter Papillary ca: - Seen in iodine sufficient areas - MC thyroid malignancy Anaplastic ca: - Rare; mc seen in females - Usually seen in 7th - 8th decade of life Medullary ca: - Arise from Parafollicular C cells - C cells derived from ultimobranchial bodies 