<prompt> In free water clearance, free water is generated in?PCTDescending limb of loop of HenleAscending limb of loop of HenleAll of the above  <response>: Ans. is c i.e., Ascending limb of loop of HenleRef: Medical physiology for undergraduate E-book p 4381Free water or solute free water is generated in the diluting segments of the kidney i.e. thick ascending limb and early distal tubules, where NaCl is reabsorbed and free water is left in the tubular fluid. 