<prompt> Which of the following RCC do not have papillary architecture in histology ?Xp11 translocation carcinomaBellini duct carcinomaSuccinate dehydrogenase-deficient RCCPapillary carcinoma  <response>: Succinate dehydrogenase deficient renal cell carcinoma SDD-RCC It is very rare type of RCC It is defined by WHO as a malignant epithelial tumor, composed of vacuolated eosinophilic to clear cells with loss of immunohistochemical expression of SDHB gene. Features : Characteristic flocculent cytoplasmic vacuoles with a pale eosinophilic, bubbly appearance and low grade nuclei Image : SDD-RCC showing cytoplasmic vacuoles which impas a bubbly appearance. 