<prompt> Lambe Eaton syndrome is associated withThymomaOat cell syndromeMyasthenia gravisAdenocarcinoma of lung  <response>: Lambe-Eaton myasthenic syndrome LEMS is a rare autoimmune disorder that is characterized by muscle weakness of the limbs. Lambe-Eaton myasthenic syndrome is caused by autoantibodies to the presynaptic membrane. Myasthenia gravis is caused by autoantibodies to the postsynaptic acetylcholine receptors.Around 60 of those with LEMS have an underlying malignancy, most commonly small cell lung cancer Ref Harrison20th edition pg 2345 