<prompt> Acute Hepatitis B is indicated by:HBsAgHBcAgHBeAgAnti HBc IgM  <response>: Acute Hepatitis B is indicated by Anti HBc IgM. Markers of hepatitis B infection: HBsAg Epidemiological marker of hepatitis B infection. Earliest marker seen in infection. Also seen in chronic infection. HBcAg HBe Indicates active viral replication. Marker of infectivity for Hepatitis B. Anti-HBc First antibody to appear in serum. IgM anti-HBc is a marker of acute Hepatitis B. IgG anti-HBc is a marker of chronic Hepatitis B. 