<prompt> A 25 year old male presents with recurrent lip edema to the OPD. On performing lab investigations, it revealed C4, C1-INH levels, C1-INH function, normal C1q levels. What is the most probable diagnosis?Hereditary angioedema Type 1Hereditary angioedema Type 2Acquired angioedema Type 1Acquired angioedema Type 2  <response>: Hereditary angioedemaHAE Disorder characterized by recurrent episodes of severe swelling angioedema. 3 main types of HAE. Type I and II are caused by a mutation in the SERPING1 gene that makes the C1 inhibitor protein while type III is often due to a mutation of the factor KhII gene. This results in increased amounts of bradykinin which promotes swelling. Distinguishing bw HAE AAE Acquired angioedema: C1q levels normal-HAE C1q levels low-AAE Type 1 HAE-Low C1-INH level low C4 level Type 2 HAE- Normal or elevated C1-INH level low C4 level. Function of C1-INH is reduced in both type 1 2 HAE. 