<prompt> Which of the following is not a pyrogenic cytokineIl_1TNFIFN _alphaIL -18  <response>: Ref Harrison 18e p 144;9e p99 Interleukin-18 is a protein which in humans is encoded by the IL18 gene. The protein encoded by this gene is a proinflammatory cytokine. This cytokine is produced by many immune cells and can modulate both innate and adaptive immunity and dysregulation can cause autoimmune or inflammatory diseases 