<prompt> Which component of sulfasalazine is responsible for the therapeutic effect in rheumatoid ahritisIntact sulfasalazine moleculeSulfapyridine5-aminosalicylic acidBoth B and C  <response>: Sulfasalazine:- It is a compound of sulfapyridine and 5-amino salicylic acid 5-ASA; exes antiinflammatory activity and is useful in ulcerative colitis, RA patients. mechanism of action:- Sulfapyridine split off in the colon by bacterial action and absorbed systemically appears to be the active moiety contrast ulcerative colitis, in which 5-ASA acting locally in the colon is the active component. Generation of superoxide radicals and cytokine elaboration by inflammatory cells may be suppressed. Ref:- kd tripathi; pg num:-211 