<prompt> All the following statements about mitral valve prolapse are true exceptIt is more common in femalesMost patients are symptomaticIt has a benign clinical courseTransient cerebral ischemic is a know complication  <response>: Ref Harrison 19 th ed pg 1546 Most patients are asymptomatic and remain so for their entire lives. However, in Noh America, MVP is now the most common cause of isolated severe MR requiring surgical treatment. 