<prompt> Which one of the following statements about non insulin dependent diabetes mellitus NIDDM is NOT true-Circulating islet cell antibodies are usually foundThere is no HLA associatonKetosis is rareRelative resistance to insulin is present  <response>: Circulating islet cell antibodies are usually found in Insulin Dependent Diabetes Mellitus IDDM. Non insulin dependent diabetes mellitus NIDDM has no HLA association unlike IDDM which is associated with HLA haplotypes DR3 andor DR4. Ketosis is rare in NIDDM whereas hyperglycemic hyperosmolar state HHS is more common. NIDDM is a heterogeneous group of disorders characterized by variable degrees of insulin resistance, impaired insulin secretion, and increased glucose production. 