<prompt> Best drug for chemoprophylaxis in a pregnant woman who is traveling to chloroquine resistant falciparum malaria endemic zone?MefloquineDoxycyclineAtaquinoneProguanilPrimaquine  <response>: Ans. A. Mefloquine. Ref. H-17thpg 1292; Table 203-6Best drug for chemoprophylaxis in a pregnant woman who is traveling to chloroquine resistant falciparum malaria endemic zone is Mefloquine.Regimens for the Rx of MalariaType of Disease or RxRegimensUncomplicated Malaria Known chloroquine- sensitive strains of Plasmodium vivax, P. malariae, P. ovale, P. falciparumChloroquine 10 mg of basekg stat followed by 5 mgkg at 12, 24, and 36 h or by 10 mgkg at 24 h and 5 mgkg at 48 h or Amodiaquine 10-12 mg of basekg qd for 3 daysRadical Rx for P. vivax or P. ovale infectionIn addition to chloroquine or amodiaquine as detailed above, primaquine 0.25 mg of base kg qd; 0.375-0.5 mg of basekg qd in Southeast Asia and Oceania should be given for 14 days to prevent relapse. In mild G6PD deficiency, 0.75 mg of basekg should be given once weekly for 6 weeks. Primaquine should not be given in severe G6PD deficiency.Sensitive P. falciparum malariaArtesunate 4 mgkg qd for 3 days plus sulfadoxine 25 mgkgpyrimethamine 1.25 mgkg as a single dose or Artesunatec 4 mgkg qd for 3 days plus amodiaquine 10 mg of basekg qd for 3 days.Multidrug-resistant P. falciparum malariaEither artemether-lumefantrinec 1.59 mgkg bid for 3 days with food or artesunatec 4 mgkg qd for 3 days plus Mefloquine 25 mg of basekg-either 8 mgkg qd for 3 days or 15 mgkg on day 2 and then 10 mgkg on day 3.Second-line RxRx of imported malariaEither artesunatec 2 mgkg qd for 7 days or quinine 10 mg of saltkg tid for 7 days plus 1 of the following 3: 1. Tetracycline 4 mgkg qid for 7 days;2. Doxycycline 3 mgkg qd for 7 days3. Clindamycin 10 mgkg bid for 7 days or Atovaquone-proguanil 208 mgkg qd for 3 days with food.Severe Falciparum Malaria7Artesunate 2.4 mgkg stat IV followed by 2.4 mgkg at 12 and 24 h and then daily if necessary or Artemetherc 3.2 mgkg stat IM followed by 1.6 mgkg qd or Quinine dihydrochioride 20 mg of saltkg7 infused over 4 h, followed by 10 mg of saltkg infused over 2-8 h q8h or Quinidine 10 mg of basekgh infused over 1-2 h, followed by 1.2 mg of basekg per hour with electrocardiographic monitoring. 