<prompt> Which of the following is secondary mediator of the anaphylaxis isHistamineProteaseEosinophilic chemotactic factorLeukotriene B4  <response>: ref Robbins 9e p203 Leukotriene B4 LTB4 is a leukotriene involved in inflammation. It is produced from leukocytes in response to inflammatory mediators and is able to induce the adhesion and activation of leukocytes on the endothelium, allowing them to bind to and cross it into the tissue. 