<prompt> A young woman who has suffered recurrent aboions, presents with thrombosis of leg veins. The most likely diagnosis isChromosomal abnormalityFactor VIII deficiencyAntiphospholipid antibody syndromeIncreased antithrombin III levels  <response>: Anti phospholipid syndrome - Vascular thrombosis Recurrent pregnancy loss 3 spontaneous aboions 10 weeks Death of normal fetus 10 weeks Premature bih at 34 weeks due to pre-eclampsia or placental insufficiency Laboratory Features:1. Elevated anticardiolipin antibodies IgG or IgM2. Elevated Anti beta-2 glycoprotein -1 Antibody3. Presence of Lupus Anticoagulant LA in plasma 