<prompt> A biopsy was performed for a patient with recurrent chalazion involving the upper lid. The most likely diagnosis on histopathology is:Sebaceous cell carcinomaBasal cell carcinomaSquamous cell carcinomaMalignant Melanoma  <response>: Ans. a Sebaceous cell carcinomaRef: Kanski 7e, p. 21, 4Sebaceous Gland Carcinoma Typically arises from meibomian glands or glands of ZeisQ Most frequently arises from the upper eyelids? where meibomian gland are most frequent in contrast to basal cell and squamous cell carcinoma Highly malignant with mortality of 5-10 Elderly females are typically affected. Nodular SGC masquerades a chalazion and hence any patient with recurrent chalazion with an unusual consistency should undergo a full thickness resection and histological examination to exclude SGC. 