<prompt> Acantholysis, resulting from desmosome weakening by autoantibodies directed against the protein desmoglein, is the disease mechanism attributed to which of the following?Epidermolysis bullosaMucous membrane pemphigoidPemphigus vulgarisHerpes simplex infections  <response>: In pemphigus vulgaris, autoantibodies attach to antigens desmoglein found in desmosomes that keep keratinocytes linked to each other. Cells eventually separate from each other acantholysis, resulting in short-lived intraepithelial vesiclesbullae. 