<prompt> The organ most vulnerable to ischaemia due to shock-LungsAdrenalsKidneyHeart  <response>: The susceptibility of a tissue to hypoxia influences the likelihood of infarction.Neurons are most sensitive to hypoxia irreversible changes develop in 3-4 minutes followed by myocardial cells irreversible changes develop in 20-40 minutes.Fibroblasts are amongst the most resistant cells to hypoxia. 