<prompt> All are TRUE about Fabry disease, EXCEPT:X-linked dominant disorderPremature atherosclerosis is seenRetinitis pigmentosa is well described in FabryAccumulation of ceramide trihexoside in nerves and blood vessels  <response>: Fabry disease angiokeratoma corporis diffusum is an X-linked dominant disorder. Angiokeratomas are reddish-purple maculopapular lesions that are usually found around the umbilicus, scrotum, and perineum. Premature atherosclerosis is a feature that often lead to death by the fifth decade of life. Some patients also manifest a dilated cardiomyopathy. Fabry disease is due to mutations in the Alpha-galactosidase gene that leads to the accumulation of ceramide trihexoside in nerves and blood vessels. Retinitis pigmentosa is not a feature of Fabry, it is a feature of Refsum disease. Refsum disease can manifest with the classic tetrad of 1 peripheral neuropathy, 2 retinitis pigmentosa, 3 cerebellar ataxia, and 4 elevated CSF protein concentration. 