<prompt> Insulin secretion is normally stimulated by ?GLP-1GLP-2VIPa-adrenergic receptors  <response>: Ans. is a i.e., GLP-1Recently, attention has been focused on glucagon - like polypeptide 1 7-36 GLP-1 as an additional gut factor for insulin secretion and GLP-1 7-36 is more potent insulinotropic hormone.Regulation of insulin secretion Factors affecting insulin secretion are : -i Simulating insulin secretion :- Glucose; Mannose; Amino acids arginine, leucine; Intestinal hormones GIP. Gastrin, Secretin, CCK, GLP -1; b-keto acids; Parasympethetic stimulation acetylcholine; cAMP; b-adrenergic stimulation; theophylline; Sulfonylureas; and ceain endocrine hormones like growth hormone, Glucagon and glucocoicoids.ii Inhibiting insulin secretion : - Somatostatin; 2-deoxyglucose; mannoheptulose; a-adrenergic stimulation, P-adrenergic inhibitors; galanin; Diazoxide; Thiazide diuretics; K depletion; Phenytoin; Alloxan; microtubule inhibitors; and insulin itself. 