<prompt> Which of the following antineoplastic drug is used to prevent synechiae formation after endoscopic nasal proceduresActinomycinMitomycinEpirubicinPentostatin  <response>: Topical Mitomycin - C is used to prevent synechiae formation after endoscopic nasal procedures.It is an antitumor antibiotic which acts by inhibiting Topoisomerase - II. It is used topically to avoid systemic side effects.Mitomycin is used for anal carcinoma, bladder carcinoma and laryngotracheal stenosis. 