<prompt> Benign prostatic hyperplasia first develops in thePeriurethral transition zonePeripheral zoneCentral zoneAnterior fibromuscular stroma  <response>: Benign prostatic hyperplasia arises from submucosal glands of periurethral transitional zone with stromal proliferation and adenosis forming a nodular enlargement. It eventually compresses the peripheral zone glands into a false capsule and causes the appearance of typical lateral lobes. Reference : page1345 Bailey and Loves sho practice of surgery 25th edition 