<prompt> Amphotericin B Fungizone IV is given to a client with aspergillosis, a fungal infection. In order to prevent its side effects, the nurse anticipate administering which of the following prior, except?Hydrocortisone.Ketoconazole.Diphenhydramine.Meperidine.  <response>: Azole antifungals eg, ketoconazole decreases the effectiveness of amphotericin b.Options A and C: Fever, shaking, chills, flushing, loss of appetite, dizziness, nausea, vomiting, headache, shortness of breath, or fast breathing may occur 1 to 3 hours after the infusion is started. Medications such as acetaminophen, diphenhydramine, corticosteroids such as hydrocortisone may be necessary to prevent these side effects.Option D: Meperidine 25 to 50 mg IV has been shown in some patients to decrease the duration of shaking chills and fever that may accompany the infusion of amphotericin B. 