<prompt> Alkaline phosphatase level on serum is not increased in -Pagets diseaseMultiple myelomaHyperparathyroidismOsteomalacia  <response>: Important Causes of raised alkaline phosphatase.Bone diseases - Paget disease, Osteomalacia, rickets, hyperparathyroidism, fresh fracture, Vit D deficiency. Metastatic bone tumors.Obstructive biliary tract disease - Primary biliary Cirrhosis, biliary stone, Primary sclerosing cholangitis.Hepatic causes - Infiltrative granulomatous hepatitis, sarcoidosis, amyloidosis, malignancy, viral hepatitis.Drugs - Estrogen, Chlorpromazine, erythromycin.Placental - Pregnancy, post menopausal, tumors. 