<prompt> Morphologically diagnostic feature of cancer cells -T SizeT Mitotic activityT CytoplasmT Lysosomes  <response>: Ans. is b i.e., T Mitotic activity Benign Vs malignant neoplasm Criteria o Differentiation o Growth limits o Growth rate o Invasivness o Metastasis o Mitotic figures o Cell size shape o Nuclear to cytoplasmic ratio o Stroma o Cell orientation Polarity o Nuclear chromatin o Blood supply Benign Well differentiated Limited, encapsulated Usually slow Non-invasive Non-metastatic Rare Uniform Normal I :4 to 1:6 Abundant Normal Normal Adequate Malignant cancer Well differentiated to undifferentiated anaplastic Unrestricted, no surrounding capsule Often rapid, but can be slow Invasive Metastatic Atypical, with increased number Pleomorphism Increased 1:1 Often scanty Disorganized loss of polarity Hyperchromatasia Often inadequate thus areas of necrosis 