<prompt> Most common primary tumour of the heart:MyxomaFibromaMyomaAngioma  <response>: Ans: a Myxoma Ref: Robbins, 7th ed, p. 613; Harrison, 16th ed, p. 144The most common primary tumours of the heart, in the descending order of frequency are myxomas, fibromas, lipomas, papillary fibroelastomas, rhabdomyomas, angiosarcomas and other sarcomas.Myxomas MC primary tumour of the heart MC site: Fossa ovalis in atrial septum, left atria Histological feature: Stellate or globular myxoma, lepidic cells CF: Most common presentation similar to that of mitral valve disease i.e. MS or MR Constitutional symptoms: fever, malaise etc OE: tumour plop- low pitched Rx. Surgical removal is curative.Myxoma associated syndromes CARNEY syn:Multiple cardiac extracardiac myxomas, spotty pigmentation, endocrine hyperactivity LAMB syn:Lentigines. atrial myxoma, blue naevi NAME syn:Nevi, atrial myxoma, myxoid neurofibroma, ephelidesBRIDGECarneys triad:- Paraganglioma Gastric leiomyosarcoma Pulmonary chondroma 