<prompt> Which of the following drug is used against bacteria Pseudomonas aeruginosa?Piperacillin-TazobactumCefotaximeStreptomycinCephalexin  <response>: Ans. a. Piperacillin-Tazobactum Ref: KDT 7e p724; Goodman Gillman 10e p1174 Piperacillin-Tazobactum is used against bacteria Pseudomonas aeruginosa.Piperacillin is used inPseudomonas infectionQKlebsiella infectionQAnaerobic-Bacteroides infectionQDrugs for Pseudomonas aeruginosaAntipseudomonalCephalosporins CeftazidimeQ CefoperazoneQ cephalosporin excreted in bile therefore not given with probenecidQAntipseudomonal penicillins Carboxy penicillins: e.g. CarbeniciilinQ and TicarcillinQ Ureidopenicillins: e.g. AzlocillineQ, MezlocillineQ, PiperacillineQlmipenamQ It is the most spectrum beta-lactam antibiotic active against pseudomonasAztreonamQ It is a beta-lactam antibiotic with only one lactam ring i.e. monobactam.Quinolones CiprofloxacinAminoglycosides GentamycinQ, TobramycinQ and AmikacinQ are used for gram -ve infections. Outstanding feature of Amikacin is its resistance to bacterial aminoglycoside inactivating enzymeQPolypeptide Polymyxin BQ and ColistinQ Colistin is more potent in Pseudomonas.Vancomycin does not act on PseudomonasQ.Bacitracin does not act on PseudomonasQ. 