<prompt> Earliest symptoms in acute appendicitis is ?PainFeverVomitingRise of pulse rate  <response>: Ans. is a i.e., Pain Schwaz writes - In more than 95 of patients with acute appendicitis, anorexia is the first symptom, followed by abdominal pain, which is followed in turn, by vomiting if vomiting occurs. If vomiting precedes the onset of pain, the diagnosis of appendicitis should be questioned. 