<prompt> Permeability of which of the following ion leads to resting membrane potential?ChloridePotassiumSodiumCalcium  <response>: Ans. B PotassiumRef: Ganotig, 22nd ed. BRS Physiology, 4th ed. pg. 11Ionic Basis of Nerve Resting Membrane Potential RMP: Resting membrane potential is potential difference across the cell membrane in millivolts, which is by convention -70mV. RMP is established by diffusion potential that results from concentration differences of permeable ions. Resting membrane potential -70mV is close to equilibrium potential of K and Cl- both -85mV and far from the equilibrium potential of Na 65mV. That means at rest the nerve membrane is more permeable to K than Na Na is actively transported out of neurons and other cells and K is actively transported into cells, but because K permeability at rest is greater than Na permeability, K channels maintain the resting membrane potential. 