<prompt> Patient complaints of muscle weakness. It was rivers on administration of neostigmine becauseIt blocks action of acetylcholineIt interferes with the action of monoamine oxidaseIt interferes with the action of carbonic anhydraseInterferes with the action of Acetyl chlolinesterase  <response>: Ref: Katzung 11e p105 Neostigmine acts by inhibiting the enzyme acetylcholinesterase. This enzyme is involved in degradation of ACh,consequently neostigmine inereases the synaptic level of ACh. Muscle weakness can be improved by stimulation of NM receptors at muscle end plate due to increased ACh. 