<prompt> Which of the following is responsible for adhesion of platelets to the vessel wall?Von Willebrand factorFactor IXFibrinogenFibronectin  <response>: the Von-Willebrand factor is responsible for adhesion of platelets to the vessel wall.Endothelial injury allows platelets to contact the underlying extracellular matrix;subsequent adhesion occurs through interactions with von Willebrand factor VWF,which is a product of normal endothelial cells and an essential cofactor for platelet binding to matrix elements. 