<prompt> Beta galactosidase deficiency causes?Goucher diseaseKrabbes diseaseFabrys diseaseNeimann Pick disease  <response>: Ans. is b i.e., Krabbes disease Krabbe disease, also known as globoid cell leukodystrophy or galactosylceramide lipidosis, is an autosomal-recessive sphingolipidosis caused by deficient activity of the lysosomal hydrolase galactosylceramide beta-galactosidase GALC.GALC degrades galactosylceramide, a major component of myelin, and other terminal beta-galactose-containing sphingolipids, including psychosine galactosylsphingosine.Beta-galactosidase is a lysosomal enzyme responsible for catalyzing the hydrolysis of gangliosides. The deficiency of this enzyme can lead to 1 of the following conditions: GM1 gangliosidosis, Morquio syndrome B, and galactosialidosis. 