<prompt> Fordyce spots are seen on-LipsTongueFingersNails  <response>: Ans. is a i.e., Lips Fordyce spots Fordyce granules or Fordyce disease Fordyces spot represents ectopic sebaceous glands on lips most common site and oral mucosa. They may also appear on vulva and penis, where they are called Tysons gland, i.e., ectopic sebaceous gland at penis prepuce and vulva is called tysons gland. These glands have histopathology similar to normal sebaceous glands, despite their ectopic location. They are regarded as hamartomas as they are not associated with hair follicles In contrast to normal sebaceous glands which have their ducts in hair follicles. Fordyces spot is totally benign condition which occurs in normal people. It is characterized by discrete, pin-head sized superficial, light or yellow milium-like, maculo-papular lesions in mucous membrane of lips especially vermilion portion, and sometimes buccal mucosa. The condition usually appears at puberty and is more common in males. Fordyces spots are often confused with kopliks spot of measles - There is erythmatous halo around the Kopliks spot which is not there in Fordyces spot As the condition is asymptomatic, no treatment is required, other than reassurance. Oral isotretinoin can be used for large disfiguring spots. 