<prompt> In all of the following conditions neuraxial blockade is absolutely contraindicated, exceptPatient refusalCoagulopathySevere hypovolemiaPreexisting neurological deficits  <response>: Contraindications to neuraxial block spinal epidural Absolute :- Infection at the site of injection, patient refusal, coagulopathy or other bleeding disorder, severe hypovolemia, increased ICT, severe aortic or mitral stenosis.Relative :- Sepsis, unco-operative patient, pre-existing neurological deficit, demyelinating lesions, severe spinal deformity, stenotic valvular heart disease. 