<prompt> Which of the following estimates blood creatinine level most accurately -Jaffe methodKinetic jaffe methodTechnicon methodEnzyme assay  <response>: Among the given options, the enzyme assay is the most accurate.Methods to measure serum creatine to assess GFR are:-i Gas chromatography-isotope dilution mass spectroscopy GC-IDMS:- It is the most accurate and method of choice.ii High-performance liquid chromatography HPLC.iii Enzymatic creatinine method enzyme assay.ivAlkaline picrate methods:- Jaffe methodAccuracy in decreasing order is GC-IDMS HPLC Enzyme assay Alkaline picrate Jaffe method. 