<prompt> Prophylactic craniospinal irradiation is required inMedulloblastomaMeningomaOligodendrogliomaAll of the above  <response>: Craniospinal irradiation is required in CNS tumors which can spread through CSF like Medulloblastoma, CNS lymphomas. It is also required in case of highly malignant tumors like glioblastoma multiforme. 