<prompt> Which of the following organism plays an impoant role in pathogenesis of malt workers lung?Aspergillus clavatusAspergillus fumingatusPseudomonasMicropolyspora faeni  <response>: Hypersensitivity pneumonitis HP, or extrinsic allergic alveolitis, is an inflammatory disorder of the lung involving alveolar walls and terminal airways that is induced by repeated inhalation of a variety of organic agents in a susceptible host. Malt workers lung is caused by Aspergillus fumigatus or A. clavatus and source of antigen is moldy barley. Examples of Hypersensitivity Pneumonitis HP: Disease Antigen Source of Antigen Bagassosis Farmers lung Thermophilic actinomycetes Moldy bagasse sugar cane, hay, grain, silage Bird fanciers, breeders, or handlers lung Parakeet, pigeon, chicken, turkey proteins An droppings or feathers Compost lung Aspergillus Compost Humidifier or air conditioner lung ventilation pneumonitis Aureobasidium pullulans, Candida albicans, Thermophilic actinomycetes, mycobacterium spp., other microorganisms Contaminated water in humidification or forced-air air conditioning systems Millers lung Sitophilus granarius wheat weevil Infested wheat flour Mushroom workers lung Thermophilic actinomycetes, Hypsizygus marmoreus, Bunashimeji, and other exotic mushrooms Mushroom compost; mushrooms Potato riddlers lung Thermophilic actinomycetes, Aspergillus Moldy hay around potatoes Sausage workers lung Penicillium nalgiovense Dry sausage mold Tap water lung Mycobacteria spp. Contaminated tap water Tobacco workers disease Aspergillus spp. Mold on tobacco Wine Growers lung Botrytis cinerea Mold on grapes Wood trimmers disease Rhizopus spp., Mucor spp. Contaminated wood trimmings Woodmans disease Penicillium spp. Oak and maple trees Woodworkers lung Wood dust, Alternaria Oak, cedar, pine, and mahogany dusts Ref: Gerke A.K., Hunninghake G.W. 2012. Chapter 255. Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo Eds, Harrisons Principles of Internal Medicine, 18e. 