<prompt> Gowers sign is seen inDuchenne muscular dystrophyCongenital myopathyGullian barre syndromeAll of the above  <response>: Ans. a Duchenne muscular dystrophy Duchennes muscular dystrophy is an X-linked recessive condition where boys suffer from disease while girls are carriers. The protein defective is dystrophin due to defect of dystrophin gene on chromosome Xp.21. Boys present between 3-5 years of age with clumsy gait and history of recurrent falls. The gait is peculiar and is known as waddling gait. Most children become wheel chair bound by 12- 15years of age. Gower sign is a characteristic feature characterized by child getting up gradually. On physical examination pseudo-hypertrophy called so because of the physical appearance but actually has fat deposition around the muscles. The weakness of respiratory muscles results in recurrent pneumonia that ultimately results in mortality.Investigations CPKMM EMG and nerve conduction velocity Muscle biopsy and western blot analysis of tissue specimen 