<prompt> Gauchers disease is due to enzyme deficiency ofGlucocerebrosidaseSphingomyelinaseHexosaminidaseCeramidase  <response>: A Glucocerebrosidase Gaucher disease refers to a duster of autosomal recessive disorders resulting from mutations in the gene encoding glucocerebrosidase. This disease is the most common lysosomal storage disorder. This affected gene encodes glucocerebrosidase, an enzyme that normally cleaves glucose residue from ceramide As a result, glucocerebroside accumulates principally in the phagocytic cells of the body but in some forms also in the central nervous system. Glucocerebrosides derived mainly from the cell membranes of leukocytes and erythrocytes. 