<prompt> Hereditary chronic pancreatitis is caused by mutation ofCationic trypsinogen or PRSS1CFTRPTSISPINK1  <response>: Hereditary pancreatitis Autosomal dominant disease Due to a missence mutation on cationic trypsinogen, or PRSS1Protease, serine 1 results in premature, intrapancreatic activation of trypsinogen The incidence is equal in both sexes Ref: Sabiston 20th edition Pgno :1532 