<prompt> Submicroscopic deletions of any size can be detected by:Multiplex ligation-Dependent probe amplification MLPASouthern blottingCytogenomic array technologyChromosome painting  <response>: a. Multiplex ligation-Dependent probe amplificationRef: Nelsons 20e p 605, Ghai 8e p 6045Multiplex Ligation-Dependent Probe Amplification MLPA: It is a technique which mixes DNA hybridization, ligation, PCR amplification to detect deletions duplications of any size, including anomalies that are too large to be detected by PCR and too small to be identified by FISH. 