<prompt> Which of the mentioned drugs most commonly causes acute liver failure?WarfarinTetracyclineParacetamolValproate  <response>: Ans. c i.e. ParacetamolRef: Goodman Gilman 13th EP696 All mentioned drugs can cause hepatotoxicity and liver failure, but the most common drug overall implicated in drug poisoning and suicidal attempts is paracetamol. Hence liver failure is most commonly seen with paracetamol. In case of fulminant liver failure liver transplantation is required. 