<prompt> Which of the following drugs is effective against HIV with Y181C mutation?FestinavirLersivirineElvitegravirDolutegravir  <response>: LersivirineFestinavir is a NRTI shown to be effective in adefovir and tenofovir resistanceLersivirine is a NNRTI effective against HIV with Y181C mutationElvitegravir is a integrase inhibitor used for initial naïve treatmentDolutegravir is a integrase inhibitor approved for raltegravir-resistant infections 