<prompt> What is not seen in massive resection of small bowel ?HypogastrinemiaB12 DeficiencyMalabsorptionNone  <response>: Ans is None Sho bowel syndrome Is the malabsorptive condition that arises secondary to removal of significant segments of the small intestine. The MC causes are -- Mesentric infarction, Crohns ds, Trauma Changes seen in Terminal ileal resection Resection of terminal ileum results in malabsorption of bile salts and Vit. B12 which are normally absorbed in this region Vit Biz Malabsorption --- Megaloblastic anemia Bile salts malabsorption -- unabsorbed bile salts escape into colon where they stimulate fluid secretion from the colon, resulting in watery diarrhoea. -- Reduction in bile salt pool lead to steatorrhea and malabsorption of fat soluble vitamins due to malabsorption of fat. Unabsorbed fatty acids bind with calcium, and thus lead to increased concentration of free oxalates oxalates bind with calcium normally and therefore escape without intestinal absorption Free oxalates are absorbed. Increased conc. of body oxalates lead to oxalate kidney stones Due to decreased bile salts in the bile -- Cholesterol gall stones result. If the ileocecal valve is removed ? bacterial overgrowth from the colon -4 diarrhoea malabsorption decrease in intestinal transit time Resection of other segments Duodenal resection may result in folate, Iron, or calcium malabsorption. Large resection of intestine may result in gastric hypersecretion dt reduced hormonal inhibition of acid secretion Increase gastric acid -- diarrhoea steatorrhoea A massive resection may result in nutrients, water and electrolyte malabsorption. Weight loss occurs because of malabsorption diarrhoea. 