<prompt> Drug of choice for CMLImitanib mesylateFludarabineA1 trans retinoic acid for AML 3Methotrexate  <response>: Ans. a Imitanib mesylate Doc for CML GIST - Imatinib MesylateRef. KD Tripathi 6th Ed. 828 832IMATINIB It inhibits the tyrosine protein kinases in chronic myeloid leukaemia CML cells and and c-kit receptor found in gastrointestinal stromal tumour GIST. Adverse effects are fluid retention, edema, vomiting, abdominal pain, myalgia and liver damageDrugs of choice for some commonly asked malignanciesMalignancyFirst line drugsChronic Lymphatic leukaemiaFludarabineChronic Myeloid leukaemiaImatinibHairy cell leukemiaCLADRIBINEMultiple myelomaMelphalanChoriocarcinomaMethotrexateProstate carcinomaBicalutamideFlutamide 