<prompt> MCH located on -Chromosome number 6Chromosome number 7Chromosome number 8Chromosome number 9  <response>: A Chromosome number 6 136 Baveja 4lh 106 D. Greenwood 18thMAJOR HISTOCOMPATIBILITY COMPLEX MHO The MHC in human is known as human leucocyte antigen HLA complex. The HLA complex of genes is located on short arm of chromosome 6. They are arranged over a region of between 2000 and 4000 kilobases is size, containing sufficient DNA for more than 200 genes.HLA Complex MHC complexClass IClass 11Class III Comprising A, B and C loci D region - DR, DQ, DPComplement region encodes Responsible for Responsible for C2C4 Graft rejection Graft versus host response Properdin factor B Cell mediated cytolysis Mixed leucocyte reaction Heat shock protein Found on the surface of all nucleated cells and platelets Found only on cells of the immune system TNF a and b Enzyme 21 hydroxylaseIndications of HLA typing: Tissue typing prior to transplantation. Paternity determination. Disease and HLA - associationHLA - B27 - Ankylosing spondylitis.HLA - DR4 - Rheumatoid arthritis 