<prompt> Lysosomal accumulation of sphingomyeline is seen in-Niemann-Pick diseaseFarbers diseaseTay Sachs diseaseKrabbes disease  <response>: Ans. is a i.e., Niemann-Pick disease DiseaseEnzyme deficiencyLipid accumulatedTay-sach diseaseHexosaminidase AGM2 gangliosideSandoff diseaseHexosaminidase BGM2 gangliosideNiemann-Pick diseaseSphingomyelinaseSphingomyelineFarbers diseaseCeramidaseAcyl-sphingosine ceramideFabrys diseasea-galactosidaseGlobotrisylceramideKrabbes diseaseb-galactosidase GalactosylceramidaseGalactosylceramideGauchers diseaseb-glucosidase glucocerebrosidaseGlucosylceramideMetachromatic leukodystrophyArylsulfatase A3-Sulfogalactosylceramide 