<prompt> HLA-B27 is associated with:Gouty arthritisRheumatoid arthritisAnkylosing spondylitisSystemic lupus erythematosis  <response>: Ankylosing spondylitis: Ref 59- A, 1937-HAnkylosing spondylitis: - There is a strong tendency to familial aggregation and association with the genetic marker HLA - B27 HLA -DR4 occurs in about 70 of people with Rheumatoid arthritis 51 -A HLA - B27 markers associated with - Reiters syndrome, Acute anterior uveitis, Reactive arthritis, Psoriatic spondylitis SLE is associated with HLA DR2 DR3 