<prompt> Regarding retinoblastoma all of the following are true, EXCEPT:13q14p mutationAutosomal dominant25 Bilateral40 Heritable forms  <response>: Hereditary retinoblastoma accounts for 40 of cases. All bilateral and cases and about 15 of the unilateral cases are hereditary. Retinoblastoma gene has been identified as 14 band on the long-arm of chromosome 13 13q14. Deletion or inactivation of this protective gene by two mutations results in occurrence of retinoblastoma. Inheritance is autosomal dominant and the risk of transmitting the gene mutation is 50. Because of high penetrance 40 of offspring of a surviver of hereditary retinoblastoma will develop the tumor. 33 are bilateral 13rd cases. Ref: Ophthalmology by A K Khurana 4th edition, Page 280 