<prompt> Mode of action of Fluoxetine is -GABA inhibitionAdrenergic neuron blocking agentInhibition axonal uptake of 5HTAlpha adrenergic stimulation  <response>: Ans. is c Inhibit axonal uptake of 5HT Fluoxetine is a tricyclic antidepressant like imipramine, AmitriptylineWhile typically TCA inhibit uptake of both NA and 5HT by neurons.Fluoxetine is selective serotonin reuptake inhibitor SSRITherefore it is devoid of following side effectsAnticholinergic SedationHypotensionOther SSRIsFluvoxamineParoxetineAlso remember mechanism of action of these atypical TCAsTianeptine - It increase rather than inhibit 5-HT uptake Mianserin - does not inhibit either NA or 5-HT uptake, it blocks presynaptic alpha-2 receptors, increases release and turnover of NA in brain 