<prompt> In cholecystectomy, fresh frozen plasma should be given -Just before operationAt the time of operation6 hours before operation12 hours after operation  <response>: The question is incomplete. It should be A cirrhotic patient with abnormal coagulation needs cholecystectomy, FFP should be given: Transfusions with FFP are given to replenish clotting factors. The effectiveness of the transfusion in maintaining hemostasis is dependent on the quantity of each factor delivered and its half-life. The half-life on the most stable clotting factor, factor VII, is 4 to 6 hours. A reasonable transfusion scheme would be to give FFP on call to the operating room. This way the transfusion is complete prior to the incision, with circulating factors to cover the operative and immediate postoperative period. 