<prompt> Most severely affected child in Rh-isoimmunisation patients :Rh negative mother with Rh positive in 2nd childRh positive mother with Rh negative in 2nd child Rh positive mother with Rh negative in 15 childRh positive mother with Rh negative in 15 childRh positive mother with Rh positive in 2d child  <response>: Rh negative mother with Rh positive in 2nd child 