<prompt> Regarding cutaneous amoebiasis which is not true -It is a spreading necrotizing inflammation of the skin and cutaneous tissueRapid improvement with anti-amoebic treatment occursCan occur in the perianal regionThe infection reaches the skin through the blood stream  <response>: Option 1, 2, 3, 4 1. Cutaneous amoebiasis or Amoebiasis cutis- it is usually seen over the region adjoining a visceral lesion e.g. area of drainage of liver abscess or colostomy wound or from the rectum perianally. It may also be seen following anal intercourse. 2. Perianal skin ulcers: by direct extension of ulcers to perianal skin. 3. Amoeboma Amoebic granuloma: a diffuse pseudotumor like mass of granulomatous tissue found in rectosigmoid region and sometimes growing sufficiently large to block the lumen 4.Rapid improvement with anti-amoebic treatment occurs. D.O.C:- metronidazole 