<prompt> Premalignant lesion for carcinoma rectum isFamilial polyposisFAPJuvenile polypAdenomatous polyp  <response>: This autosomal dominantly inherited condition is characterised by the development of multiple rectal and colonic polyps around pubey. A colonoscopy and biopsy will confirm the diagnosis.as this condition is pre-malignant, a total colectomy must be performed; often, the rectum can be preserved, but regular flexible endoscopy and removal of polyps before they develop carcinoma are required. Ref: Bailey Love;s Sho Practice of Surgery,E25,Page-1228,1229 