<prompt> HIV infects most commonly:CD4helper cellsCD8cellsMacrophageNeutrophil  <response>: Ans. is a i.e., CD4 Helper cells The receptor for the virus is the CD4 antigen on surface. The cells affected are:- CD4 T Cells major target.- B lymphocytes.- Monocytes and macrophages.- Langerhans cells in dermis.- Glial cells and microglia in the CNS.- Follicular dendritic cells from tonsils can be infected by HIV without the involvement of CD4. 