<prompt> DOC for nephrogenic diabetes insipidus:MannitolSpironolactoneThiazidesDemeclocycline  <response>: Ref: Goodman Gillmans 13th ed. P 466 Nephrogenic DI may be congenital or acquired. Causes can be: Hypercalcemia, hypokalemia, post obstructive renal failure, Li, foscarnet, clozapine, demeclocycline, and other drugs can induce nephrogenic DI. Thiazide diuretics reduce the polyuria of patients with DI and often are used to treat nephrogenic DI. DOC for central diabetes insipidus: Desmopressin V2 receptor agonist DOC for nephrogenic diabetes insipidus: Thiazide diuretics. DOC for lithium induced diabetes insipidus: Amiloride 