<prompt> Which of the following drug is contraindicated in variant angina?DiltiazemNitratesPropranololVerapamil  <response>: Variant angina is caused by coronary vasospasm DOC:Sublingual Nitroglycerine Prophylaxis : Calcium channel blockers like verapamil and Diltiazem and nitrates Beta blockers are avoided as they may precipitate coronary vasospasm by counteracting beta 2 mediated coronary vasodilation. Therefore they are avoided in variant angina. 