<prompt> Hybridoma technique is used to obtainSpecific antigenComplementSpecific antibodyInterleukins  <response>: Hybridoma technique is used to produce Monoclonal antibodies mAb Nobel prize Gwardee Kohler and Milstein: Hybridoma technique:- Monoclonal antibodies mAb are defined as the antibodies derived from a single clone of plasma cell; all having the same antigen specificity-- i.e. produced against a single epitope of an antigen. Principle- B cells fused with myeloma cells on HAT media hypoxanthine aminopterine thymine media Types of Monoclonal Antibodies: Mouse mAb contains 100 mouse derived proteins. The mouse proteins being foreign; can induce immune response in humans producing human anti-mouse antibody HAMA; that in turn eliminate the mAb faster from the body. Chimeric mAb is prepared by recombination of 34 mouse proteins variable region and 66 human proteins constant region. Humanized mAb: Here, only the antigen binding site is mouse derived 10 and the remaining pa of mAb is human derived. Human mAb: 100 of amino acids are human derived. It is the best accepted mAb. 