<prompt> Massive splenomegaly is not seen in: September 2008MalariaChronic myelogenous leukemiaSyphilisSickle cell anemia  <response>: Ans. D: Sickle cell anemiaThe causes of massive splenomegaly include:ThalassemiaVisceral leishmaniasis Kala AzarSchistosomiasisChronic myelogenous leukemiaChronic lymphocytic leukemiaLymphomasHairy cell leukemiaMyelofibrosisPolycythemia veraGauchers diseaseNiemann Pick diseaseSarcoidosisAutoimmune hemolytic anemiaMalariaSyphilis may show splenomegalySplenic insufficiency due to splenectomyautoinfarction is seen in sickle cell disease. 