<prompt> A 12 year old girl with the mood and emotional liability has a golden brown discoloration in descement membrane. Most likely diagnosis isFabrys diseaseWilsons diseaseGlycogen storage diseaseAcute rheumatic fever  <response>: Emotional liability, tremors Neurological symptoms with brown discoloration of descemets membrane of coenea suggest the diagnosis of Wilsons disease.Wilsons disease -It occurs due to reduced mobilization of copper from lysosomes in liver cells for excretion into the bile.Abnormal gene for Wilsons disease is on long arm of chromosome 13 AR.Clinical features -Younger patient likely to develop hepatic involvement.Later on Neurologic manifestation like tremor, dystonia, behavioral changes also develops.K-F rings may be absent in young patients with liver diseases but are always present in patient with neurologic symptoms.Hemolysis may be an initial manifestation.Sensory changes never occur.Diagnosis -Decrease ceruloplasmin levelLiver biopsy 