<prompt> A patient developed fixed drug eruptions after taking ceain medications. Which of the following drug will give rise to these skin lesions in this patient?PhenolphthaleinAspirinDapsoneAll of the above  <response>: A fixed drug eruption FDE is an adverse cutaneous reaction to an ingested drug, characterized by the formation of a solitary but at times multiple erythematous patch or plaque. Most commonly implicated agents in fixed drug eruptions: Tetracyclines tetracycline, minocycline Sulfonamides, other sulfa drugs Metronidazole, nystatin, salicylates, NSAIDs, phenylbutazone, phenacetin Barbiturates Oral contraceptives Quinine including quinine in tonic water, quinidine Phenolphthalein Food coloring yellow: in food or medications Ref: 2013. Section 23. Adverse Cutaneous Drug Reactions1. In Wolff K, Johnson R, Saavedra A.P. Eds, Fitzpatricks Color Atlas and Synopsis of Clinical Dermatology, 7e. 