<prompt> In which of the following breast malignancy is the highest bilateral involvement observed?Lobular CaDuctal CaMedullary CaSchirrhous adenocarcinoma  <response>: Invasive lobular carcinoma ILC comprises approximately 10 of breast cancers. ILC was significantly more likely to occur in older patients, to be larger in size, to be estrogen and progesterone receptor positive, to have lower S-phase fraction, to be diploid, and to be HER-2, p53, and epidermal growth factor receptor negative. It was more common for ILC than for infiltrating ductal carcinoma IDC to metastasize to the gastrointestinal tract and ovary. The incidence of contralateral breast cancer was higher for ILC patients. 