<prompt> All of the following statements about trientine use in Wilsons disease are true except:It is more potent than penicillamine.It is used as an alternative to penicillamine in non-tolerant patientsIt should not be administered with in two hours of iron supplementationIt can cause iron def anemia which is reversible by oral iron supplements  <response>: Penicillamine is the most potent chelating agent useful in Wilsons disease. Trientine is not as potent as penicillamine and was used in patients unable to tolerate penicillamine.However,now a days, trientine is preferred because of severe adverse effects of penicillamine. Trientine cause fewer adverse effects other than mild anemia due to iron deficiency in few patients. Ref: KATZUNG 14TH ED. 