<prompt> Which of the following is the characteristic pathological feature of Parkinsons disease?Lewy bodiesBabes noduleNeurofibrillary tangleNegri bodies  <response>: Lewy bodies are inclusion bodies found within neurons in parkinson s disease. Bodies are single or multiple, intracy- toplasmic, eosinophilic, round and elongated inclusions that often have a dense core surrounded by a pale halo. Ultrastructurally: These are composed of fine filaments densely packed in the core but loose at the rim. They are composed of a - synuclien, neurofilament antigens, parkin, and ubiquitin. Pathologic examination in parkinsons shows the following: Gross macroscopically: pallor of the substantia nigra and locus coeruleus Microscopic examination: Loss of catecholaminergic neurons in these regions gliosis Lewy bodies. 