<prompt> In gram negative septicemia, early findings setting before shock of florid is -Cardiac output, T Total peripheral resistanceCardiac output, i Total peripheral resistanceCardiac output, t Total peripheral resistanceCardiac output, i Total peripheral resistance  <response>: The pathophysiology of septic shock is not entirely understood, but it is known that a key role in the development of severe sepsis is played by an immune and coagulation response to an infection. Septic shock involves a widespread inflammatory response that produces a hypermetabolic effect in septic shock Cardiac output, i Total peripheral resistance Ref Davidson 23rd edition pg 445 