<prompt> Muscarinic cholinergic agonistsDecrease production of IP 3Activate inhibitory G-proteins GiDecrease release of intracellular calciumInhibit the activity of phospholipase C  <response>: In addition to activating inhibitory G-proteins Gi, muscarinic cholinergic agonists stimulate the activity of phospholipase C, increase production of IP 3, and increase release of intracellular calcium. Ref:- KD Tripathi 