<prompt> Cyanides shows its toxicity by binding to the following:Cytochrome oxidaseAcetylcholinesteraseAlpha adrenergic receptorsHistamine  <response>: Cyanide is a chemical asphyxiant; binding to cellular cytochrome oxidase, it blocks the aerobic utilization of oxygen. Whole-blood levels higher than 0.5-1 mgL are considered toxic. The conventional cyanide antidote package consists of amyl and sodium nitrites, which produce cyanide-scavenging methemoglobinemia, and sodium thiosulfate, which accelerates the conversion of cyanide to thiocyanate. Ref: Blanc P.D. 2012. Chapter 57. Cyanide. In K.R. Olson Ed, Poisoning Drug Overdose, 6e. 