<prompt> In case of hill journey, antimotion sickness drugs are best administered at:Twelve hours before commencing journeyOne hour before commencing journeyImmediately after commencing journeyAt the first feeling of motion sickness  <response>: Ref: KDT 6e p641 Hyoscine is administered half to one hour before journey for prevention of motion sickness. It has no role once the vomiting stas. 