<prompt> Which of the following drugs require dose adjustment in renal failureCefoperazoneDoxycyclineStreptomycinRifamipicin  <response>: Ref Katzung 10r p 835 Streptomycin is an aminoglycoside and require dose adjustment in renal failure whereas Doxycycline, Rifampicin and cefoperazone are secreted in bile and do not require dose adjustment in renal failure 