<prompt> Thiamin status of an individual can be detected by which of the following testsenzymes in erythrocytes?TransaldolaseGlucose-6-phosphataseTransketolaseEnolase  <response>: Severe thiamine deficiency is associated with: Decreased RBC transketolase activity this is the earliest manifestation seen even before clinical disturbances Thiamin is a cofactor of Transketolase pyruvate, alpha-ketoglutarate and lactate level in blood increases in thiamine deficiency ref: DM Vasudevan 8th ed page 467 