<prompt> Which of the following is caused by defective tyrosine metabolism?Richner-Hanha syndromeNeonatal tyrosinemiaAlkaptonuriaAll of the above  <response>: Metabolic diseases of tyrosine catabolism include tyrosinosis, Richner-Hanha syndrome, neonatal tyrosinemia, and alkaptonuria. Ref: Harper 28th edition, chapter 29. 