<prompt> All of the following are poor prognostic factors in Multiple Myeloma, Except:AzotemiaHypocalcemiaLDHHigh M component production  <response>: Answer is B Hypocalcemia Hypercalcemia is associated with a poor prognosis in Multiple Myeloma and not hypocalcemia. Azotemia 1 creatinine, T LDH, Chromosome 13q deletion and High M component production are all established poor prognostic factors. Poor prognostic factors in Multiple Myeloma Stage Related Factors Stage III disease : High Tumor Burder Hb 8.5 gd1 Hypercalcemia Ca 12 mgdl Advanced Lytic bine lesions High M component production IgG 7gdi IgA 5gdl Urine light chains 12g24 hrs Subclassification based on serum creatinine levels Serum creatinine 2 mgdl Independent factors b2 microglobulin single most impoant factor Serum albumin LDH labeling index age of cells undergoing mitosis CRP or IL6 THepatocyte growth factor, TGF 3 or syndecan - 1 Plasmoblastic morphology Genetic Abnormalities -Hyperploidy - Chromosome 13 deletion and chromosome 17 p deletion - t4; 14, t14; 16, t11; 4 translocation - RAS P53 mutations. 