<prompt> Action of metalloproteinase ?Degradation of collagenPolymerization of collagenOxidation of collagenStimulation of collagen  <response>: Ans. is a i.e., Degradation of collagenDegradation of collagen and other ECM extracellular matrix proteins is achieved by matrix metalloproteinases MMPs.MMPs is a family of enzymes that have in common a 180-residue zinc protease domain.Matrix metalloproteinases include :-Interstitial collagenase MMP-1, 2, and 3 : Cleave the fibrillar collagen types I, II and III.Gelatinases MMP-2 and 9 : Degrade amorphous collagen and fibronectin.Stromelysins MMP-3, 10 and 11 : Act on proteoglycans, laminin, fibronectin and amorphous collagen.Membrane-bound MMPs ADAMs : Cleave membrane-bound precursor forms of TNF and TGF-a, releasing the active molecule. 