<prompt> JAK-STAT kinase receptors is associated with ?T cAMPIP3 - DAGIon channelsNuclear transcription  <response>: Ans. isdi.e., Nuclear transcriptionJAK-STAT-Kinase binding receptors:These receptors differ in not having intracellular enzymatic action on receptor itself. Agonist binding induces interaction of these receptors with free intracellular tyrosine kinase - Janus kinase JAK.jAK phosphorylates activators of transcription STAT, which then regulate the nucleus transcription resulting in a biological response.Examples - Growth hormone, Prolactin, 