<prompt> Substrate affinity to enzyme in Competitive inhibitionDecreasesIncreasesAny of the aboveDoes not change  <response>: Significance of Km Michaelis Constant:Km is substrate concentration at 12 VmaxConstant for an enzyme substrate pairIt is called signature of the enzymeHigher the Km, lower is the affinity of the enzyme towards the substrateLower the Km, higher is the affinity of the enzyme towards the substrate.Features of competitive inhibition:Km increases, hence the affinity is loweredVmax remains the same.Features of noncompetitive inhibition:Km remains the sameVmax decreases. 