<prompt> Plasma cells are activated:B cellsT cellsMacrophagesMonocytes  <response>: Ans: a B cells Ref: Robbins,7th ed, p. 199; Ananthanarayan, 7th ed, p. 125When B lymphocytes are activated by antigens proteinnon-protein they get differentiated into antibody secreting cells, called plasma cells.Plasma cells:Cartwheel appearanceLifespan-2-3 daysMakes Ab of single specificity, single Ig clan allotype.Immune mechanism: Produce only a single light chain only.B lymphocytes-plasma cells- ImmunoglobulinT lymphocytes- lymphokine production - Cell mediated immunity.Differentiation between B lymphocyte and T lymphocyte. T cells form E rosetteSRBC rosette; B cells form EAC rosette B cells carry Ig on their surface; T cells have T cell receptors TCR B cell blast transformation with bacterial endotoxin, staph, aureus, EBV; T cell blast transformation with phytohemagglutinin, concanavalin A 