<prompt> A 25 year - old female gives a history of redness, pain and mild diminution of vision in one eye for past 3 days . There is also a history of low backache for the past one year. On examination there is circumcorneal congestion, cornea is clear apa from a few fine keratic precipitates on the corneal endothelium, there are 2 cells in the anterior chamber, anterior chamber depth being normal and the intraocular pressure is within normal limits. The patient is most likely suffering from :Acute attack of angle closure glaucomaHLA B-27 related anterior uveitisJIA associated uveitisHerpetic keratitis  <response>: History of backache with features of anterior uveitiscircumcorneal congestion, few fine keratic precipitates on the corneal endothelium, 2 cells in the anterior chamber point towards HLA B27 associated uveitis. Seronegative spondyloahropathies-all are HLA B-27 positive . Sacrolitis low back pain is earliest manifestation. MC Extra Aicular Manifestation- Uveitis JIAJuvenile Idiopathic Ahritis- It usually develops before the age of 6 years. Pauciaicular, ANA positive , RF negative In 75 of Patients suffering from JIA associated with anterior uveitis have antinuclear antibodies ANA positive HIGHEST association In 50 of Patients suffering from JIA associated with anterior uveitis have predisposition due to HLA-DW5 