<prompt> A 17 year girl presented with absent thelarche and primary amenorrhea. On examination hypoplastic uterus was present. Investigation showed high FSH. Karyotype is XO. What is the probable diagnosis?Gonadal dysgenesisAndrogen insensitivity syndromeKallman syndromeAdrenal hyperplasia  <response>: Gonadal dysgenesis Hypoplastic Uterus Functional ovarian Tissue absent Thelarche absent as it depends on ovarian steroids FSH LH High: Due to absent negative feedback on pituitary by ovarian hormones i.e.Hypergonadotropic Hypogonadism Pubic and axillary hairs presentDepends on Androgen External Genitalia Female likeHypoplastic Androgen Insensitivity has a normal female phenotype in a genetic male. Adrenal hyperplasia can happen at later age but the Uterus will be present and FSH will be normal. Kallman syndrome is Hypothalamic amenorrhea. Since there is no GnRH, there is no FSH LH. 