<prompt> Which of the following drugs is Topoisomerase 1 inhibitsDoxorubicinIrinotecanEtopsideVincristine  <response>: Refer KDT 6e p 825, Camptothecin derivatives like topotecan and irinotecan act by inhibiting Topoisomerase -1whereras epipodophylotoxins and anthracycline act by inhibiting Topoisomerase -2 