<prompt> Coombs positive hemolytic anemia associated with:TTPPANSLEHUS  <response>: Answer is C SLE Coombs positive hemolytic anemia is a feature of autoimmune hemolytic anemia and is characteristically seen in SLE. Polvaeritis Nodosa PAN may also be associated with a Coombs positive hemolytic anemia. However this association is rare, and more commonly patients with PAN present either with an anemia of chronic disease or a microangiopathic hemolytic anemia. TTP and HUS are characteristically associated with Coombs negative microangiopathic hemolytic anemias. 