<prompt> DAX 1 gene Mutation is associated withCushings diseaseHashimotos diseaseCongenital adrenal hypoplaisaAddisons disease  <response>: Ans. C. Congenital adrenal hypoplasiaExplanationDAX1 mutation is seen in congenital adrenal hypoplasia.DAX1 dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1 is a nuclear receptor protein encoded by the NROBlgene.DAX1 plays an important role in the normal development of several hormone-producing tissues.The adrenal glands,The pituitary gland andHypothalamusThe testes and ovariesMutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism 