<prompt> A 50-year old male, working as a hotel cook, has four dependent family members. He has been diagnosed with an early stage squamous cell cancer of anal canal. He has more than 60 chances of cure. The best treatment option is:Abdomino-perineal resectionCombined surgery and radiotherapyCombined chemotherapy and radiotherapyChemotherapy alone  <response>: Answer is C Combined chemotherapy and Radiotherapy A combination of chemotherapy and radiotherapy called as chemoradiation is the preferred initial therapy for all anal canal tumors - Bailey 