<prompt> which of the following is hallmak of CHRONIC INFLAMMATION ?tissue destructionmononuclear infiltrationwound healing and repairall of the above  <response>: Chronic Inflammation Definition: Inflammation of prolonged duration in which active inflammation, tissue injury and the healing proceed simultaneously Causes: Persistent Infections Ex. Treponema palladium causative organism of syphilis Organism of low toxicity and evoke an immune reaction delayed hypersensitivity Prolonged Exposure to toxic Agents Autoimmunity Ex. Autoimmune diseases . ref : robbins 10th ed 