<prompt> Duration of action of flumazenil is:5 minute10 minute20 minute1-2 hours  <response>: Flumazenil is absorbed orally ;oral bioavailability is 16 but its not used orally .On I.v .injection ,action of flumazenil stas in seconds last for 1-2 hours ;elimination t12 is 1 hour due to rapid metabolism. REF: KD Tripathi 8th ed. 