<prompt> Cotton wool spots are commonly seen in AE -HIVDMHypeensionCMV  <response>: Cotton wool spots are fluffy white lesions and represent the areas of infarcts in the nerve fibre layer. These occur due to ischaemia caused by capillary obliterations in severe hypeensive retinopathy. Due to their cotton wool feathery appearance they are also termed as soft exudates misnomer Ref;A.K.Khurana; 6th edition; Page no: 274 