<prompt> A 2-year-old infant is diagnosed with meningitis. A lumbar puncture reveals numerous neutrophils and gram-positive cocci in pairs that appear encapsulated. She is admitted to the hospital and started on intravenous IV b-lactams. Which of the following targets would most likely play a role in the development of resistance to this antibiotic in the most likely etiologic agent of this childs meningitis?BactoprenolDNA gyrasePenicillin-binding proteinReverse transcriptase  <response>: Trans peptidases, or penicillin-binding proteins PBPs c, are inactivated when bound to penicillin. Altered PBPs no longer bind the b-lactam antibiotic. The acquisition of a new PBP or modification of the existing one is the mechanism by which S. pneumoniae, the most likely etiologic of this childs meningitis, become resistant to b-lactams. Altered PBPs are also seen in N. gonorrhoeae, S. aureus, and other bacteria. Bactoprenol a is not known to be involved in antibiotic resistance. Fluoroquinolones target the DNA gyrase b, while rifamycins target the bacterial RNA polymerase e. Bacteria do not utilize reverse transcriptase d. 