<prompt> Which hormone does not act through cAMP -TSHAdrenalineInsulinACTH  <response>: Ans. is c i.e., Insulin TYPES OF RECEPTORSMembrane receptorso Present on the cell membrane.o Their drug.;hormone binding domain is extracellular and effector domain is intracellular,o These are:G protein coupled receptors - It may act through.Adenylyl cyclase cAMP - TSH, FSH, LH, ACTH, glucagon, PTH, adrenaline, calcitonin, vasopressin V2. cAMP - PR1H DopamineIP.-DAG Ca2 and protein kinase c - Vasopressin V1, oxytocin.Channel regulation Ca2, K, NaReceptor with Intrinsic ion channels - Nay K, Ca-2 or Cl-Enzyme linked receptorsIntrinsic enzyme receptors tyrosine kinase receptors - Insulin.JAK-STAT kinase binding receptors - Growth hormone, Prolactin.Intracellular receptors transcription factors!o Present inside the cell and induce synthesis of specific protein by increasing the expression of specific gene.Cytoplasmic - Glucocorticoids. Mineralocorticoids, Androgens, Progestins. Nuclear - Thyroxine, Triiodothyronine, Estrogen, retinoic acid, Vit D. 