<prompt> A patient with cerebellar problems and spider angiomas is diagnosed with a combined T-cell and B-cell deficiency known as ataxia- telangiectasia. In addition to a defect in this patients DNA repair enzymes, which immunoglobulin is the primary antibody in saliva, tears, and intestinal and genital secretions, and is also deficient in this illness?IgGIgAIgMIgD  <response>: IgA antibody is involved in local immunity at the level of the mucous membrane. It also arises early in disease, is short lived, and will disappear similarly as IgM. 