<prompt> The drug which is used for long term maintenance in opioid addiction:NaloxoneNalorphineButarphamolMethadione  <response>: D i.e. Methadone Naloxone is used in opioid overdoseQ and ultrarapid detoxification of opioid dependent addictsQ. Due to sho duration of action t12 1-2 hour, frequent dosing is required, which makes it unsuitable for maintenance treatmentQ. Naltrexone Nalmefene are used in rapid detoxification and maintenance of ultrarapid detoxification in opioid addicts dependent. And methadone is used in sho term detoxification, long term detoxification long term maintenance in opioid dependant addictsQ. 