<prompt> Which of the following interacts with Digitalis maximally-FurosemideTriamtereneAmilorideSpironolactone  <response>: Ans. is a i.e., Furosemide o Two classes of diuretics are given in the options Loop Diuretics --- Furosemide cause hypokalemia Potassium sparing diuretics --- Spironolactone, Trimetrene, Amiloride cause Hyperkalemia We know that digitalis toxicity is potentiated by hypokalemia. So the drug interacting with digitalis will be Furosemide as it causes Hypokalemia. 