<prompt> Drugs used in the treatment of pruritus in PBC?RifampicinNaltrexoneCholestyramineAll of the above  <response>: The main symptoms of PBC are fatigue and pruritus, and symptom management is impoant.Several therapies have been tried for treatment of fatigue, but none of them have been successful; frequent naps should be encouraged. Pruritus is treated with antihistamines, narcotic receptor antagonists naltrexone, and rifampin. Cholestyramine, a bile salt-sequestering agent, has been helpful. Plasmapheresis has been used rarely in patients with severe intractable pruritus.Ref: Harrison;s Principles of Internal Medicine; 19th edition; Chapter 365; Cirrhosis and Its Complications Page no: 2061 