<prompt> In which of the following age group myelodysplastic syndromes MDS are most common?10-Feb15-2025-4050  <response>: Idiopathic MDS is a disease of the elderly; the mean age of onset is 68 years. There is a slight male preponderance. MDS is rare in children, but monocytc leukemia can be seen. Therapy- related MDS is not age-related and may occur in as many as 15 of patients within a decade following intensive combined modality treatment for cancer. So the single best answer of choice is 50. Ref: Harrisons Principles of Internal Medicine, 16th Edition, Pages 624-25; R Alagappan Manual of Practical Medicine, 3rd Edition, Page 352-53. 