<prompt> Fronto temporal dementias include AEPicks diseaseNonfluent aphasiaSemantic dementiaAlzheimers disease  <response>: D i.e. Alzheimers disease Alzheimers disease, the most common cause of dementiaQ initially presents with minor forgetfulness gradually progressive sho term memory lossQ making learning of new information difficult. Language is usually affected early with difficulty in finding words or naming objects, impairments in the ability to construct fluent informative sentences. The memory is lost for recent events first with a delayed loss of long term memory mainly affecting episodic memoryQ. It is a parieto temporal disease. Multi infarct or vascular dementia or atherosclerotic psychosis, the 2,0 most common cause of dementia not Alzheimers disease is caused by cerebro- vascular disease ischemia or infarctQ. It is characterized by an abrupt onset, acute exacerbations lit repeated infarcts, stepwise wise step-ladder pattern progressionQ i.e. impairment of memory intellect, fluctuating course periods of deterioration fb paial recovery for few months and presence of hypeension m.c., cardiovascular disease ho previous stroke or transient ischemic attack. Lewy Body dementia, the 2,,d most common cause of degenerative dementia characteristically presents with progressive fluctuating dementia affecting cognition, attention visuosptial ability, recurrent delirium like phase, systematized delusions, visual hallucinations usually well formed detailed, motor features of Parkinsonism bradykinesia tremor, rigidity, extra pyramidal symptoms, neuroleptic sensitivity syndrome to antipsychoticsQ, together with repeated fallsQ, syncope, transient loss of consciousness, autonomic dysfunctions eg. ohostatic hypotension urinary incontinence. It is like Parkinsons disease a synucleinpathy reflecting abnormal aggregation of eosinophilic inclusion Lewy bodies i.e. a synuclein ubiquitin in cytoplasm of neurons of neocoex substantia nigra. Picks disease in contrast to parietal - temporal- Alzheimers ds,Q is a prototype fronto- temporal dementia. It classically presents with insidious onset gradually progressive behavioural personality changes frontal lobe function and language disorder such as aphasia - left temporal lobe function usually preceding or overshadowing patients cognitive problems. Patients may show apathy medial frontal damage, disinhibition basal - frontal dysfunction, symptoms of kluver Bucy syndrome i.e. hypersexuality, hyperorality, placidity, and a compulsion to attend to any visual stimulus and loss of drive, motivation, insight and spontaneity of speech frontal language. The striking pathological findings is Knife blade atrophy of frontal temporal poles with Picks cells ballooned neurons and Picks inclusion body irregular, silver staining, intracytoplasmic bodies composed of tau, ubiquitin etc that displace nucleus towards periphery. Fronto- temporal dementias include - Picks disease, lobar atrophyQ, frontal lobe degeneration non- Alzheimers type, fronto temporal dementia with parkinsonism, motor neuron diseaseQ MND with dementia, semantic dementiaQ with aphasia agnosia, progressive nonfluent aphasic syndromeQ. Sometimes not always coicobasal degeneration, progressive supranuclear palsy parkinsonism dementia complex of Guam are also included. 