<prompt> AIDS kidney changes -MCDFSGSMPGNBerger disease  <response>: FSGS may be primary idiopathic or secondary to one of the following conditions: In association with other conditions, such as HIV infection HIV nephropathy or heroin abuse heroin nephropathy As a secondary event in other forms of GN e.g., IgA nephropathy As a maladaptation to nephron loss Ref: Robbins basic pathology 9th edition pg no;525 Renal lesions and manifestations. Features of renal impairment may appear due to HIV-associated nephropathy and genitourinary tract infections including pyelonephritis. Ref: Textbook of pathology Harsh Mohan 6th edition page 72 