<prompt> Splenectomy is done to tide over the acute crises of uncontrollable:ITPTTPHUSAll of the above  <response>: Indications of splenectomy in ITP: Failure of medical therapy Prolonged use of steroids with undesirable effects Most cases of first relapse Splenectomy provides a permanent response without subsequent need for steroids in 75-85 of patients. Laparoscopic splenectomy has become the gold standard for ITP patients. Responses usually occur within the first postoperative week. 