<prompt> Vitamin K dependent clotting factors include the following, EXCEPT:Factor VIIFactor VIIIProthrombinFactor IX  <response>: Factors II prothrombin, VII, IX, and X require vitamin K for their synthesis. Vitamin K is required for the posttranslational carboxylation of glutamic acid, which is necessary for calcium binding to gamma-carboxylated proteins such as prothrombin factor II; factors VII, IX, and X; protein C; protein S; and proteins found in bone osteocalcin and vascular smooth muscle e.g., matrix Gla protein. Warfarin-type drugs inhibit gamma-carboxylation by preventing the conversion of vitamin K to its active hydroquinone form. Ref: Weitz J.I. 2011. Chapter 30. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In B.C. Knollmann Ed, Goodman Gilmans The Pharmacological Basis of Therapeutics, 12e. 