<prompt> A patient on amphotericin B develops hypokalemia of 2.3 meq1. K supplementation required:AIIMS November 2013, Nov 201240 mEq over 24 hours60 mEq over 24 hours80 mEq over 24 hours120-160 mEq over 24 hours  <response>: Ans. d. 120-160 mEq over 24 hours Ref: Cecil Textbook of Medicine by GoldmannAusiello Renal and Genitourinary Diseases 22e p685Except in unusual circumstances, the total amount of potassium administered daily should not exceed 200 mEq.Potassium SupplementationA prudent protocol to follow is to add potassium chloride to IV solutions at a final concentration of 40-60 mEqL and to administer no more than 10-20 mEqL of potassium per hour.Except in unusual circumstances, the total amount of potassium administered daily should not exceed 200 mEq.IV potassium replacement is indicated for patients with severe hypokalemia and for those who cannot take oral supplementation.For severe deficiency, potassium may be given through a peripheral IV line in a concentration that should not exceed 40 mEqL, at the rates upto 40 mEqLHour.Continuous ECG monitoring is indicated and the serum potassium levels should be checked every 3-6 hours.For the initial administration, avoid glucose containing fluid to prevent further shift of potassium into the cellsqQMagnesium deficiency also needs to be corrected at the same time, particularly in refractory hypokalemiaQ. 