<prompt> Cytokines are secreted in sepsis and Systemic Inflammatory Response Syndrome SIRS by:NeutrophilsAdrenal glandCollecting ductRenal cortex  <response>: Cytokines are peptide mediators or intercellular messengers which regulate immunological, inflammatory and reparative host responses. They are produced by widely distributed cells like macrophage, monocytes, lymphocytes, platelets, fibroblast, endothelium, stromal cells etc. 