<prompt> If there is a Gs alpha subunit gain-of function mutation, this results inDecreased cAMPDecreased IPIncreassed GTPase activityIncreased cAMP  <response>: The Gs alpha subunit Gas, Gsa is a subunit of the heterotrimeric G protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase. Gsa is a GTPase that functions as a cellular signaling protein Ref-Harper 28e p447 