<prompt> Multiple intrahepatic bile duct dilation with bile lakes and concurrent sepsis is suggestive ofCarolis diseaseWatson Algali syndromePrimary sclerosing cholangitisKlatskin tumor  <response>: Carolis disease Clinical features : Symptoms include cholangitis 64, poal hypeension 22 and abdominal pain18 More common in males Septa containing poal veins protrude into the lumen of the ecstatic bile ducts central dot sign The main and often the only symptom of bacterial cholangitis secondary to carolis disease is fever without abdominal pain and jaundice Frequent episodes of cholangitis indicates poor prognosis Most stones are pigmented in carolis disease Ref: Sabiston 20th edition Pgno :1511 