<prompt> Which of the following genetic mutations involved in breast carcinomaAPCBRCAHbAcRB gene  <response>: B. i.e. BRCA 786 - Harsh Mohan 5th 744- Basic-pathology 8th Genetic mutations involvement in breast carcinoma - BRCA - 1 BRCA - 2 gene, TP53 tumour suppressor gene, PTEN phosphate and tensin tumour suppressor gene APC gene - Familial adenomatous polyposis In 85 of follicular B. cell lymphomas the anti apoptotic gene BCL2 is activated by the t 8; 14 translocations RB gene associated with retinoblastoma HMB - 45, S- 100 is a an immunological marker for Melanoma CDX-2 is an immunological marker for Gastro intestinal cancer BRCA- 1 gene is located on - chromosome 17 cancer Desmin is a immuno logical marker for Rhabdomyosarcoma LMP-1 gene plays a role in oncogenesis induced by Epstein- Barr virus P53 known as guardian of the genome 