<prompt> Which of the following anticancer drugs can cause hypercoagulable state?5-FUL-asparaginaseMelphalanCarmustine  <response>: Ref: Katzung 11e p955 L-asparaginase cause the breakdown of asparagine and thus interference with protein synthesis. It can inhibit the production of clotting factors responsible for cerebal hemorrhage as well as anti-clotting protienscan lead to coical viens thrombosis and other hypercoagulable state. 