<prompt> Double arch of aorta is seen in:CATCH22Di George syndromeVelo cardiofacial syndromeAll of the above  <response>: d. All of aboveRef: Nelsons 20e p 2211-2217, Ghai 8e p 420-423Double aortic archIt is associated with a chromosome 22q11 deletion in approximately 20 of patients22q11 deletion is responsible for DiGeorge, velocardiofacial, and conotruncal anomaly face syndromes, which are often referred to using the unified terms CATCH-22 syndromeIt is also associated with VACTERL vertebral, anal, cardiac, tracheal, esophageal, renal, and limb abnormalities orCHARGE posterior coloboma, heart defect, choanal atresia, retardation, genital, and ear associations.Previously classified as: now considered part of same spectrum.Di-George syndrome thymic hypoplasia, diminished T-cell immunity, parathyroid hypoplasia with hypocalcemia andVelocardiofacialQ syndrome congenital heart disease, dysmorphism, developmental delay. 