<prompt> Drug of choice for dermatitis herpetiformis:DapsoneRifampicinKetokonazoleAzithromycin  <response>: Ans: a DapsoneRef: Katzung1468 Dermatitis herpetiformis is a chronic blistering skin condition, characterized by blisters filled with a watery fluid. DH is neither related to nor caused by herpes virus: the name means that it is a skin inflammation having an ap- pearance similar to herpes. It characterized by intensely itchy, chronic papulove- sicular eruptions, usually distributed symmetrically on extensor surfaces buttocks, back of neck, scalp, elbows, knees, back, hairline, groin, or face. Diagnosis is confirmed by a simple blood test for IgA antibodies, and by a skin biopsy in which the pattern of IgA deposits in the dermo-epidermal junction, revealed by direct immunofluorescence. Treatment: Dapsone is considered as drug of choice for DH. In case of intolerance to dapsone, other drugs which can be used are: Colchicine, Tetracycline, Sulfapyridine. 