<prompt> Which of the following is not seen in extraglandular Sjogren disease?Rheumatoid ahiritsRaynaud phenomenonLymphomaSplenomegaly  <response>: Sjogren syndrome :An autoimmune disease which targets exocrine glandsMost common glands which are affected are lacrimal glands and salivary glands causing keratoconjunctivitis sicca dry eyes and xerostomia dry mouth.Serology shows raised SS-A Ro and SS-B La antibodiesAutoantigens against which the antibodies are produced is alpha-fodrin though not confirmedExtraglandular manifestations: Rheumatoid ahritis, Synovitis, diffuse pulmonary fibrosis, peripheral neuropathy, Raynaud phenomenon and marginal zone lymphoma. Ref: Robbins 8e p221 