<prompt> A 60 yr old man is suspected of having bronchogenic ca; TB has been ruled out in this pt. What should be the next investigation :CT guided FNACBronchoscopy and biopsySputum cytologyX-Ray chest.  <response>: Answer is B Bronchoscopy and biopsy: This patient represents a case of suspected bronchogenic carcinoma. Fibreoptic bronchoscopy and biopsy is the investigation of choice as it allows direct visualization of the tumor mass and provides a means of obtaining tumor tissue for histological diagnosis. HRCT is the alternate investigation but should be done if no specific diagnosis is suggested on bronchoscopy. 