<prompt> Force not acting in an enzyme substrate complex :ElectrostaticCovalentVan der waalsHydrogen  <response>: Vander Walls forces are too weak, to actively paicipate in formation of enzyme- substrate complex. Forces contribute in binding are:- Hydrogen bondingQ- Ionic electrostatic bonding- Hydrophobic interactionEnzymes function to decrease the activation energy so that reactions can occur at normal body temperature. The substrate form a covalent bond with the enzymes active site, accelerates the reaction. 