<prompt> What is the metabolic defect in Primary Oxaluria Type II?Glycine cleavage systemAlanine glyoxalate amino transferaseD GIycerate dehydrogenaseExcess vitamin C  <response>: Ans. C. D Glycerate DehydrogenasePrimary Hyperoxaluria Type IThe most common form of Primary hyperoxaluria.It is due to a deficiency of the peroxisomal enzyme alanine glyoxylate amino transferase expressed only in the liver peroxisomes and requires pyridoxine vitamin B6 as its cofactorProtein targeting defect.Primary Hyperoxaluria Type II GlycericAciduriaDue to a deficiency of D glycerate dehydrogenase glyoxylate reductase enzyme complexSecondary HyperoxaluriaPyridoxine deficiency cofactor for alanine glyoxylate aminotransferaseAfter ingestion of ethylene glycolHigh doses of vitamin C,After administration of the anesthetic agent methoxyflurane which oxidizes directly to oxalic acidIn patients with inflammatory bowel disease or extensive resection of the bowel enteric hyperoxaluria.Nonketotic Hyper Glycinemiaa. Due to a defect in the Glycine Cleavage System 