<prompt> The number of cafe au lait macules as one of the diagnostic criteria for adult a neurofibromatosis is -1246  <response>: Ans. is d i.e., 6 o Presence of six or more cafe-au-lait macules constitutes one of the diagnostic criterias for diagnosis of neurofibromatosis Type-1.Diagnostic criteria for Neurofibromatosis 1 NF1o The patient should have two or more of the following :Six or more cefe-au-lait spots : 1?5 cm or larger in individuals past puberty. 0?5 cm or larger in individuals before puberty.o Two or more neurofibromas of any type, or one or more plexiform neurofibromas, o Two or more Lisch nodules benign iris hamartomas,o Freckling in the axilla or groin.o Optic glioma tumor of the optic pathway.o A distincive bone lesions : Dysplasia abnormal development of the sphenoid bone. Dysplasia or thinning of long bone cortex.o A first degree relative with NFL 