<prompt> Activation of which of the following hormones receptors produces E.Coli induced diarrhoea?GhrelinGuanylinVIPSomatostatin  <response>: Guanylin is a gastrointestinal polypeptide that binds to guanylyl cyclase. It is secreted by cells of the intestinal mucosa. Stimulation of guanylyl cyclase increases the concentration of intracellular cyclic 3,5-guanosine monophosphate cGMP, and this in turn causes increased secretion of Cl- into the intestinal lumen. The heat-stable enterotoxin of ceain diarrhea-producing strains of Escherichia coli has a structure very similar to guanylin and activates guanylin receptors in the intestine. 