<prompt> A 69-year-old man has lost a friend to prostate cancer, and would like to be evaluated for the disease. He has no urinary symptoms. Which of the following tests is most likely indicated to screen him for prostate cancer?prostate ultrasounddigital rectal examination DREDRE and prostate specific antigen PSAPSA  <response>: Although an elevated PSA 4 has the best positive predictive value, combining it with DRE is probably the most effective screening process. 