<prompt> According to RNTPC, case defination on sputum examination -1 sample positive out of three samplesAt least two samples positive out of two samplesAny of the two or both samples are positive out of two2 or 3 samples positive out of three  <response>: Ans. is c i.e., Any of the two or both samples are positive out of two Two sputum smear samples are examined. If any of the two samples or both the samples are positive, the diagnosis of smear-positive TB is confirmed. 