<prompt> Metastasis of carcinoma buccal mucosa goes toRegional lymph nodeLiverHeartBrain  <response>: The spread of carcinoma of buccal mucosa Buccal carcinoma spread locally and to regional lymph nodes.1 Local spread: - From its site of origin, the lesion may spread deeply involving submucosa muscle Subcutaneous fat skin. Involvement of buccinator muscle or anterior masseter causes trismus.2 Lymphatic spread: - Nodal involvement occurs in about 50 of cases. Submandibular and later the upper jugular nodes may get involved. Upper jugular nodes may also be involved, directly skipping the submandibular group. 