<prompt> Which one of the following hapatitis viruses have significant perinetal transmission ?Hepatitis E virusHepatitis C virusHepatitis B virusHepatitis A virus  <response>: Hepatitis B virus infection is prevalent in Asia, Africa,Southern europe.HBsAg seropositive ranges from 2-20.In hyperendemic areas HBV infections occur mainly during infancy and early childhood.In Asia perinatal transmission from HBsAg mother to their infants is a very impoant route of transmission,leading to chronicity.Approximately 90of the infants of HBeAg seropositive carrier mothers become HBsAg carriers,irrespective of a high or low HBsAg carrier rate in the population. Ref : ESSENTIAL PEDIATRICS,O.P.GHAI, PG NO:192, 7thedition 