<prompt> Long standing goitre leads toFollicular carcinomaColloid carcinomaMedullary carcinomaPapillary carcinoma  <response>: Long standing goitre leads to cancer, usually follicular. Dominant or rapidly growing nodules in longstanding goitres should always be subjected to aspiration cytology. Reference: Bailey Loves Sho Practice of Surgery, 27th Edition, page no 807. 