<prompt> MgSO4 have no role in prevention ofSeizures in severe pre-eclampsiaRDS in premature babyRecurrent seizures in eclampsiaNeuroprotection  <response>: Magnesium sulphate: - Mechanism of action:- Reduced presynaptic release of the neurotransmitter glutamate Blockade of glutaminergic n-methyl-d-aspaate nmda receptor Potentiation of adenosine action Improved calcium buffering by mitochondria Blockage of calcium entry voltage-gated channels Used for: - Severe preeclampsia Recurrent eclamptic seizures Neuroprotection Must check: - Urine output Respiratory rate Patellar reflexes Ref:- Williams obstetrics 25th Edition; Pg num:- 3868 