<prompt> Type 2 hypercholesterolemia occurs due to -Lipoprotein lipase deficiencyAbsence of LDL receptors on cellsAbnormality in apo ELCAT deficiency  <response>: Ans. is b i.e., Absence of LDL receptors on cells Primary hyperlipoproteinemias caused by known single gene mutationsGenetic DisorderGene DefectLipoproteinsCIfGenetic transmission1.Lipoprotein lipase deficiencyLPLChylomicronsEruptive xanthomas, HSM, pancreatitisAR2Familial apolipoprotein C-II deficiencyApoC-IIChylomicrons---AR3.Apo A-V deficiencyApoA-VChylomicrons VLDL---AD4.Familial hepatic lipase deficiencyHepatic lipaseVLDL remnantsPremature atherosclerosis pancreatitisAR5.Familial dysbetalipoproteinemiaapoEChylomicron and VLDL remnantsPalmar and tuberoeruptive xanthomas, CHD, PVDAR6.Familial hypercholesterolemiaLDL receptorLDLTendon xanthomas, CHDAD7.Familial defective apoR-100apoB-100 Arg3500-GlnLDL---AD8.AD hypercholesterolemiaPCSK9LDL---AD9.AR hypercholesterolemiaARHLDL---AR10.SitosterolemiaABCG5 or 8LDL---AR 