<prompt> Which of the following statement is true regarding pyogenic liver abscess?Diagnosis can be confirmed by serological testRadiographic features are diagnosticUsually a large and single abscess is seen in cases of direct spreadSystemic manifestations are uncommon  <response>: Ans. c Usually a large and single abscess is seen in cases of direct spread Pyogenic Liver abscess - Serology is not useful Radiographic Features are not diagnostic. Systemic manifestations are common. MC type is Solitary and Large abscess due to Direct spread from Cholecystitis, Empyema Chest and Perinephric Abscess or Subdiaphragmatic collection. 