<prompt> A chronic alcoholic have low energy production because of Thiamine deficiency as it is:Acting as a cofactor for alpha ketoglutarate dehydrogenase and pyruvate dehydrogenaseActing as cofactor for transketolase in pentose phosphate pathwayInterferes with energy production from amino acidsAct as cofactor for oxidation reduction  <response>: Ans. A. Acting as cofactor for alpha ketoglutarate Dehydrogenase and pyruvate dehydrogenaseRef. Harper 31e page 151-155Alpha ketoglutarate dehydrogenase TCA cycle and PDH link between aerobic glycolysis and TCA require Thiamine, hence affect energy production, in alcoholic patients thiamin deficiency is present. 