<prompt> Drug which is absolutely contraindicated in pregnancy is:CeftriaxoneChloramphenicolMethyldopaErythromycin  <response>: Ans. b ChloramphenicolRef KD Tripathi 6th Ed. 1716 909CHLORAMPHENICOL It is a broad-spectrum antibiotic, active against nearly the same range of organisms gram-positive and negative bacteria, rickettsiae, mycoplasma as tetracyclines.Adverse Efects Bone marrow depression Hypersensitivity reactions Grey baby syndromeChoice of drugs for common problems during pregnancyDrug class conditionUnsafe drugsSafer alternativeAntibacteirals Fluoroquinolones Tetracycline Doxycycline Chloramphenicol Streptomycin Kananmycin TobramycinPenicillin G;AmpicillinAmoxicillin-ClavulanateCloxacillin,Piperacillin cephalosphorins erythromycinAntitubercular Pyrazinamide, Ethambutol StreptomycinIsoniazidRifampicinAnti hypertensives ACE inhibitors Angiotensin antagonists Diuretics Proanolol and nitroprussideMethyldopaHydralazineAtenolol,Metoprolol, pindololNifedipineAnti thyroid drugs Carbimazole Radioactive iodine IodidePropylthiouracil PTU 