<prompt> Dorzolamide is aSecond generation sulfonylurea hypoglycaemicTopical sulfonamide antibacterialLuminal amoebicideTopically applied ocular carbonic anhydrase inhibitor  <response>: Carbonic anhydrase inhibitors Include Acetazolamide,Dorzolamide. Dorzolamide 2 eyedrops BD-TDS:- It is a topically useful carbonic anhydrase inhibitor. It lowers i.o.t. by 20; somewhat less efficacious than timolol. side effects:- Ocular stinging, burning, itching, corneal edema and bitter taste. Dorzolamide is used only as add on drug to topical b blockersPG analogues, or when these drugs are contraindicated. Ref:- kd tripathi; pg num:-155 