<prompt> A 30 years old female presents with a diffuse thyroid swelling. On investigation, TSH levels were elevated. Post-operative HPE repos showed intense lymphocytic infiltration and Huhle cells. Which of the following is the most likely diagnosis?Graves diseaseHashimotos thyroiditisFollicular carcinomaMedullary thyroid carcinoma  <response>: HASHIMOTOS THYROIDITIS- AkaStruma Lymphomatosaconversion of thyroid tissue into lymphoid tissue - Auto immune disorder -Anti- TPO anti thyroid peroxidase autoantibody - Associated with HLA B- 8, DR-3, D Clinical features - Signs symptoms of Hypothyroidism Permanent destruction of follicles- permanent hypothyroidism - Diagnosis is done by detection of anti TPO antibodies - FNAC Increased lymphocytic infiltration Presence ofHuhle cells Askanazy cells. Treatment Lifelong levothyroxine If Suspicion of malignancy - Total thyroidectomy 