<prompt> The presence of a noncompetitive inhibitor can be implicated in which of the outcome?Leads to both an increase in the Vmax of a reaction and an increase in the KmLeads to a decrease in the observed VmaxLeads to a decrease in Km and VmaxLeads to an increase in Km without affecting Vmax  <response>: In the presence of a noncompetitive inhibitor, Vmax is decreased, whereas Km is unchanged. The steady-state concentration of ES is decreased. 