<prompt> Pharmacokinetic characteristics of propranolol include Vd 300 L70 kg, C1 700 mLmin, and oral bioavailability f 0.25. What is the dose needed to achieve a plasma level equivalent to a steady state level of 20 mgL?4 mg12 mg24 mg48 mg  <response>: LD 300L x 20 mgL 0.25 6000 mg0.25 24,000 mg or 24 mg Ref:- kd tripathi; pg num:-33 