<prompt> Level of prolactin above which hyperprolactinemia term is used is?50100150200  <response>: Normal adult serum PRL levels are about 10-25 mgL in women and 10-20 mgL in men. PRL secretion is pulsatile, with the highest secretory peaks occurring during rapid eye movement sleep. Peak serum PRL levels up to 30 mgL occur between 4:00 and 6:00 a.m. The circulating half-life of PRL is about 50 min. Hyperprolactinemia refers to prolactin levels more than 200mgL in blood and most common cause is PRL-secreting pituitary adenomas called as prolactinoma. Hyperprolactinemia is the most common pituitary hormone hyper-secretion syndrome in both men and women. 