<prompt> A 2 years old child comes with one-year ho of generalised oedema. His B.P. is 10770mm urine examination shows hyaline cast, proteinuria , WBC RBC are nil. the likely diagnosis isSelective proteinuriaUremiaFocal segmental glonurulosclerosilLow serum complement level  <response>: It is a case of nephrotic syndrome due to minimal change disease MCD.MCD is the most common cause of nephrotic syndrome in childrenMicroscopic findings of urine in MCDProteinuriaPrincipally albumin which is a low molecular weight proteinHigh molecular weight proteins are seen in minimal amounts.This type of proteinuria is known as selective proteinuria.WBC AbsentRBC Absentthe hyaline cast can be seenFocal segmental Glomerulosclerosis can also cause nephrotic syndrome but the urine examination in these patients will reveal protein, WBCs and RBCs. 