<prompt> First sign of improvement in oral iron therapy is ?ReticulocytosisRaise of hemoglobinIncrease in ESRRaise in RBC  <response>: In oral Fe therapy in Fe deficiency anemia there will be initial reticulocytosis followed by Hb rise by 10gLweek continue until Hb is normal for 3 mnths. Table 2 Traditional oral iron preparations ferrous iron salts Drug Content in elementary iron Ferrous sulphate FS Can vary by manufacturer in different countries, generally 20-30 of total mg of mineral salt. Examples: 105 mg in 330 mg FS tablets Europe; 65 mg in 325 mg FS tablets US 15 mgml pediatric drops US 60 mg5 ml syrup US Ferrous glycine sulphate 100 mg in 567 mg tablets Ferrous gluconate FG Generally less than FS 10-14 of total mg of mineral salt 80 mg in 695 effervescent tablets EU; 27 mg in 240 mg FG tablets US; Ferrous fumarate FF Generally 33 of total mg of mineral salt Examples: 29.5 mg in 90 mg FF tablets; 106 mg in 325 mg FF tablets Ref : oxfords handbook of clinical medicine pg :320 Ref robbins 9e p419 