<prompt> Akalinisation of urine may be done in case of poisoning withBarbituratesAmphetamineAlcoholMorphine  <response>: A Barbiturates Forced alkaline diuresis is valuable in aspirin and barbiturate poisoning phenobarbitone.Forced alkaline diuresis Forced alkaline diuresis implies achieving an alkaline urinary pH of 7.5 to 9 This promotes excretion of drugs that are weak acidsDrugs that can be eliminated by alkaline diuresis include Salicylates Barbiturates Long acting phenobarbitone Chlorpropamide Methotrexate Lithium, Isoniazid controversial Alkaline dieresis is usually achieved with sodium bicarbonate and may be forced by using urea, furesamide or mannitol infusions.Elimination of Absorbed bv DiuresisAlkaline DiuresisAcid Diuresis Salicylates Barbiturates Amphetamine Quinine Phenylcylidine Strychnine Aldrich Mees lines on finger nails seen in poisoning of - Arsenic Burtonium line seen in Lead chronic lead poisoningClassic Triad of chronic mercury ooisonins Excessive salivationGingivitisTremorsNeuropsychialnc changes Erethism Other features- Mercuria lends - Nephritis DCT - Acrodynia - Abortion is common - Minimata disease Rain drop pigmentation of skin, hyperkeratosis of palms, lines on nails Mees line and paraesthesias are classical signs of chronic arsenic poisoning.Aluminium phosphide poisoning celphosi Aluminium phosphide produces phosphine gas on coming in contact with moisture which inhibits cytochrome c- oxidaseii AP causes wide spread organ damage due to cellular hypoxia as a consequence of non competitive inhibition of the enzyme cytochrome oxidase of the mitochondriaiii CP- retrosternal burning, epigastric pain and vomiting hypotension, restlessness, tachypnea, oliguria or anuria, jaundice, impaired sensorium and cardiac arrhythmias, focal myocardial necrosis and changes in action membrane potential to result of alteration in permeability of Na Mg Ca ionsDiagnosis1. Garlicky or decaying fish odour from mouth with highly variable arrhythmias2. Confirmation can be done by Silver Nitrate test.3. Most specific and sensitive method for detecting the pH 3 in bloodair in gas chromatographyTreatment - No specific antidote, Gastric lavage with Pottasium permagnate supportive 