<prompt> Excessive secretion of ACTH causes:Cushings syndromeAddisons diseaseMyxoedemaThyrotoxicosis  <response>: Ans. A. Cushings syndromeOverproduction of ACTH leads to Cushings syndrome. It is characterized by hyper-pigmentation and increased production of adrenocorticosteroid. These symptoms lead to negative nitrogen balance, impaired glucose tolerance, hypertension, edema, muscle atrophy etc. 