<prompt> Which finding on electron microscopy indicates irreversible cell injury-Dilatation of endoplasmic reticulumDissociation of ribosomes from rough endoplasmic reticulumFlocculent amorphous densities in the mitochondriaMyelin figures  <response>: Ans. is c i.e., Flocculent densities in mitochondria Mechanism of irreversible cell injury :? Membrane damage is the central factor in the pathogensis of irreversible cell injury. Note : o Earliest change of reversible cell injury is cellular swelling. o Myelin figures laminated structure derived from damaged membrane of organelles and plasma membrane, first appear during reversible injury, but become more pronounced in irreversible injury. 