<prompt> Apparant volume of distribution of a drug less than 5 liters implies that the drug is predominantly in which of the following compament?Extracellular fluidTotal body waterIntracellular fluidIntravascular fluid  <response>: Ans is a i.e., Extracellular fluido A drug with high volume of distribution has more concentration in tissue and less in plasma.o A drug with low volume of distribution has concentration only in plasma intravascularRelationship between volume of distribution and extent of distributionVd L body weightExtent of distribution 57only in plasma5-207-28In extracellular fluid20-4028-56In total body water4056In deep tissues; bound to peripheral tissues 