<prompt> Local anaesthesia causing methemoglobineinia -ProcainePrilocaineEtodicaineRopivacaine  <response>: O-toludine metabolites of prilocaine accumulate after large dose of drug conve hemoglobin to methemoglobin lead to methemoglobulinemia, dose depndentrange of 10mgkg Treatment of methemoglobinemia is IV methylene blue Benzocaine also cause methemoglobinemia 