<prompt> Activity of which of the following enzyme increase in alcoholism?Lactate dehydrogenaseAcid phosphataseAlkaline phosphataseGamma-glutamyltransferase  <response>: Ans. d Gamma-glutamyItransferase. Ref. Harpers Biochemistry 26th ed. 212 Increased hepatic gamma-glutamyltransferase GGT activity following chronic ethanol consumption has been attributed to enzyme induction, dietary carbohydrate imbalance, andor to hepatic cell damage. It is suggested that cellular damage following increased lipid accumulation, depletion of hepatic glutathione, or changes in biliary flow may be associated with the increased GGT activity. 