<prompt> Deficiency of which of the following enzymes is associated with Tyrosinosis:Tyrosine aminotransferase4-Hydroxyphenylpyruvate dioxygenaseHomogentisate oxidaseFumarylacetoacetate hydroxylase  <response>: Tyrosinosis is synonymous with Type-1 Tyrosinemia and is caused by a deficiency of Enzyme Fumarylacetoacetate hydrolase. Tyrosine Catabolic pathway and Associated Disorders: Tyrosine aminotransferase 4-Hydroxyphenylpyruvate dioxygenase Homogentisate oxidase Fumarylacetoacetatehydrolase Tyrosine aminotransferase Tyrosinemia type II Richner-Hanha sydrome 4-Hydroxyphenylpyruvate deoxygenase Tyrosinemia type III Complete deficiency of Enzyme 4-Hydroxyphenylpyruvate dioxygenase complex Transient Tyrosinemia of the new-born immaturity of Enzyme 4-Hydroxyphenylpyruvate dioxygenase complex Hawkinsinuria Mutant enzyme Catalyses a paial reaction Fumarylacetoacetate hydrolase Tyrosinemia type I Tyrosinosis Homogentisate oxidase Alkaptonuria Disorders associated with 4-Hydroxyphenylpyruvate dioxygenase: Immaturity of 4-hydroxyphenylpyruvate dioxygenase 4HPPD enzyme Transient neonatal Tyrosinemia TNT is a form of hypeyrosinemia produced by the complete deficiency of 4-Hydroxyphenylpyruavate dioxygenase 4HPPD leads to Tyrosinemia III. Ref: Harper 30th edition Pgno: 304 