<prompt> Which of the following statements regarding drugs used in Leprosy is falseSingle intramuscular injections of acedapsone maintain inhibitory levels of dapsone in tissues for up to 3 monthsMonthly doses of rifampicin delay the emergency of resistance to dapsoneClofazimine should not be given to patients who are intolerant to dapsone or who fail to improve during treatment with dapsoneClofazimine may cause changes in skin colour  <response>: Ref-KDT 6e p752,753 Acedapsone is a repository form of dapsone. Single i.m. injection of acedapsone keep on releasing the drug for 3 months. Rifampicin is used once in a month supervised dose for the treatment of leprosy. It prevents the emergence of resistance to dapsone. Clofazimine can result in skin pigmentation, discolouration ofsecretions and dryness of skin icthyosis. Clofazimine has no cross-allergenicity with dapsone. 