<prompt> All of the following statements are true about regulation of cholesterol synthesis, EXCEPT?HMG-CoA reductase is inhibited by mevalonateHMG-CoA reductase is inhibited by cholesterolSREBP increases the transcription of HMG-CoA reductaseThyroid hormone decreases the HMG-CoA reductase activity  <response>: Cholesterol Metabolism Mevalonate and cholesterol both allosterically inhibit HMG-CoA reductase option a and b are correct Transcription of HMG-CoA reductase gene is regulated by a transcription factor known as SREBP sterol regulatory element binding protein Binding of this SREBP protein to DNA sequences known as SRE sterol regulatory element which is located 5 to the HMG-CoA reductase gene the transcription. So SREBP increases the HMG-CoA transcription option c is correct Insulin or thyroid hormone HMG-CoA reductase activity option d is false and hence is the answer Glucagon or glucocoicoids it 