<prompt> Not true about carcinoma penis is -Erythroplasia of Queret is a precancerous condition40 of pts are under 40 year of ageCircumcision if done any time before pubey provides 100 protection against carcinoma penisMore than 50 pt. have inguinal 1.n enlargement when they prese  <response>: The circumcision that is done soon after bih in infancy gives almost complete immunity against Ca penis, but that done later in life does not have the same effect, so Muslims circumcised between the ages of 4 and 9 years are still liable to the disease. About Ca Penis Most common histological type is - sq. cell Ca 98 Erythroplasia of Queret is precancerous condition. Its the in-situ form of Ca Penis. Premalignant lesions of Ca Penis Penile cutaneous horn Balanitis xerotica obliterans Leukoplakia Viral Human papilloma virus related Dermatologic lesion Condyloma acuminata also ka genital was Bowenoid papulosis The one etiological factor most commonly associated with penile carcinoma is poor hygiene. Clinical features Age - Penile Ca occurs most commonly in the sixth decade of life, but its presentation in younger age group is not uncommon 40 of pts are under 40 years of age - Bailey Most common complaint at presentation is the lesion itself. Pain is rare. Most common site of involvement from Cambells Urology 8e, p 29.53 Glans - 48 Prepuce - 21 Both Glans Prepuce - 9 Coronal sulcus - 6 Shaft - 2 Lymph node involvement More than 50 of patients present with enlarged inguinal lymph nodes but half of these are reactive enlargement dt sepsis. The presence and the extent of metastasis to the inguinal region is the most impoant prognostic factor for survival in patients with Ca Penis. Distant metastasis is infrequent Diagnosis is made by biopsy of lesion. Treatment is discussed ahead. Ref : Bailey Love 25e p1374 