<prompt> Which of the following is a Longer acting Erythropoietin derivative?SargramostimDarbepoetin alfaDornase alfaOprelvekin  <response>: Darbopoietin is a Long acting EPO derivative drug. It has a T12 24-36 hrs. So it is given once a week. Epoietin has a half life of 6-10 hrs. Uses - Anemia of chronic renal failureCRF Anaemia in AIDS patients treated with Zidovudine. Cancer chemotherapy induced anaemia. Preoperative increased blood production for Autologous transfusion during surgery. Oprelvekin is recombinant Interleukin-11 analogue eleven Sargramostim is recombinant GM-CSF analogue 