<prompt> Which one of the following is an adverse effect associated with combined oral contraceptives ?Cerebral strokeAggravation of asthmaPeripheral neuropathyNephrotic syndrome  <response>: Ans. is a i.e., Cerebral stroke Impoant adverse effects of OCPs are : 1 Nausea, vomiting, headache worsening of migraine, 2 breakthrough bleeding, 3 mastalgia, 4 weight gain, 5 acne and hirsutism, 6 cholasma and pruritis, 7 carbohydrate intolerance, 8 leg vein and pulmonary thrombosis, 9 coronary and cerebral thrombosis MI stroke, 10 hypeension, 11 increased risk of breast and cervical carcinoma, 12 benign hepatoma, 13 gall stones, 14 precipitation of acute intermittent porphyria. 