<prompt> Vasodilatation secondary to trauma is mediated by?HistamineIL-2TGF-bFGF  <response>: Ans. is a i.e., Histamine o Principle mediators of vasodilatation in acute inflammation are Histamine, prostaglandins PGD2, PGE2, prostacyclins, serotonin, Nitric oxide, bradykinin. 