<prompt> Interleukin secreted by macrophages, stimulating lymphocytes is -INF alphaTNF alphaIL-1IL-6  <response>: Interleukin -I o Also known as leucocyte activating factor LAF or B cell activating factor BAF. Mainly secreted by macrophages and monocytes; and epithelial cells. Other sources are B-lymphocytes, fibroblasts and Endothelial cells. o Immunological effects of IL-1 Activation of T cells for the production of IL - 2. B cell proliferation and antibody synthesis Neutrophil chemotaxis and increased PMN release from bone marrow. Increases body temperature impoant endogenous pyrogen. Bone marrow cell proliferation Induction of acute phase protein. 