<prompt> BNP is degraded by:Neutral endopeptidaseElastaseOrmapatrilatACE  <response>: Brain natriuretic peptide BNP was cleaved by neutral endopeptidase NEP BNP is useful in CCF Nesiritide blocks this neutral endopeptidase thereby enhancing levels of BNP - used in CCF Ref: KD tripathi 8th ed 