<prompt> A 78-year-old retired farmer shows you the lesion below, which he has noticed on his arm. What would be the most appropriate management of this lesion?CryotherapyWatchful waitingExcision biopsyShave biopsy  <response>: Keratin horns should be excised fully including the base to allow the histological exclusion of an underlying squamous cell carcinoma. Cryotherapy will not provide a tissue for histology and Curettage or shave biopsy may yield insufficient depth for diagnosis. 