<prompt> Malignancy associated hypercalcemia is due to?Tumor lysis syndromeParathyroid related peptideIL-7IGF-b  <response>: Ans. is b i.e., Parathyroid related peptide Hypercalcemia is the most common paraneoplastic syndrome. Most commonly it is caused by parathyroid hormone-related peptide PTHRP, followed by TNF-a, IL-1, and TGF. Lymphomas cause hypercalcemia due to secretion of 1, 25 dihydroxy vitamin D Calcitriol. 