<prompt> Acetylcholine is not used commercially becauseLong duration of actionCostlyRapidly destroyed in the bodyCrosses blood brain barrier  <response>: Refer katzung 11e p 97 Acetylcholine is a neurotransmitter, which is a chemical released by a nerve cell or neuron. ... Acetylcholinecauses muscles to contract, activates pain responses and regulates endocrine and REM sleep functions. Deficiencies in acetylcholine can lead to myasthenia gravis, which is characterized by muscle weakness Acetylcholine itself does not have therapeutic value as a drug for intravenous administration because of its multi-faceted actionnon-selective and rapid inactivation by cholinesterase. 