<prompt> A person presents to OPD with tremors, visual hallucinations after 2 days history of alcohol cessation. Diagnosis is:Korsakoffs psychosisDelirium tremensWernicke encephalopathyAlcoholic hallucinosis  <response>: Ref. Oxford textbook of Psychiatry. Page. 572 Delirium Tremens Alcohol Withdrawal Delirium AWD:Most severe form of ethanol withdrawal manifested by,Mechanism: Altered mental status Global confusionAutonomic hyperactivity Sympathetic overdriveAlcohol abuse affects neurotransmitter systems in brain mainly by,Loss of GABA inhibitory mechanism - Reduces chloride ion influx.Alcohol acts as NMDA receptor antagonist - Withdrawal increases the excitatory neurotransmitter.The clinical manifestations of ethanol withdrawal are combination effects of GABA NMDA receptor activity.Thus causing tremors, diaphoresis, tachycardia, anxiety in severe cases Seizure. 