<prompt> Metopic suture usually disappears by2 years8 years4 years6 years  <response>: Frontal bone ossifies in membrane.It develops from 2 centres near frontal eminences, during 8th week of intrauterine life.At birth, the bone is in 2 halves, separated in the midline by a suture, known as metopic suture, which soon starts to fuse.It usually fuse and gets disappeared by 2 years of age.The metopic suture occasionally persists in 3 to 8 of individuals.Premature closure of metopic suture is known as metopic craniosynostosis, resulting in trigonocephaly - triangle shaped head. 