<prompt> Which of the following is not a feature of MEN typePheochromocytomaParathyroid adenomaPituitary adenomaAdrenocortical adenoma  <response>: Ans: d Adrenocortical adenomaRef: Harrison, 17 ed pg. 2359MEN I Wermers syndrome is characterized by pituitary, parathyroid pancreatic affection. Pheochromocytoma is seen in all three even though less common in MEN I MEN I wermersMEN IIA sippleMEN II BPi tut aryAdenomaHyperplasia ParathyroidHyperplasiaAdenomaCarcinomaHyperplasia PancreasIslet cell hyperplasia,AdenomaCarcinoma Adrenal Pheochromocy- tomaPheochrom- ocytomaThyroid Ccell hyperplasiaC-cell hyperplasia MedullarycarcinomaMedullary carcinomaMucocutan- eous ganglioneu- romaMarta noidHabitus Less commonPheochromo- cytomaForgut carcinoidSubcutaneous visceral lipomaDermal angiofibroma Mutant gene RETRET MEN Hirschsprung - loss of function in RET protooncogene MEN 2A - gain of function in RET protooncogene.Please dont confuse Wermers syndrome MEN 1 with Werners syndrome which is adult progeria. It is a rare condition and predisposes to papillary cancer thyroid. 