<prompt> True about Pityriasis rubra pilaris?Isolated patches of normal skin foundOccurs mainly in adultsCommon in femalesOral cyclosporine is drug of choice  <response>: Pityriasis rubra pilaris Definition: Heterogeneous group of disorders that have circumscribed follicular keratoses, branny scale and an orange-red erythema. CF: It shows an equal sex incidence. Bimodal age distribution with peaks in the first and fifth decades. Lesion: Erythematous follicular hyperkeratosis giving a nutmeg grater appearancee. Mainly seen over the elbows, knees, wrists and back of fingers. Pt. presents with well defined salmon red or orange-red dry scaly plaques. Islands of normal skin are present, the so called islands of sparing. Associated disorders: Leukaemia Metastatic carcinoma Treatment: Topical : Coicosteroids Salicylic acid if thickening. In the erythrodermic phase: Acitretin or Isotretinoin are used. 