<prompt> All are poor prognostic for multiple myeloma exceptt 11 14t 14 161q gaint 4 14  <response>: A - Commonest mutation associated with multiple myeloma is 13q deletion. Poor prognostic factor associated with multiple myeloma are: 1. t 14 16 2. 1q gain 3. 3.t 4 14 Risk Stratification in Myeloma CHROMOSOMAL ABNORMALITIES Method Standard Risk 80 Expected Survival 6-7 Years High Risk 20Expected Survival 2-3 Years Karyotype No chromosomal aberration Any abnormality on conventional karyotype Fish t 11:14 t6:14 Del13 Del 17p t4:14 t14:16 t14:20 amp 1q34 