<prompt> What is a percentage of endothelial cell loss during Descemets stripping automated endothelial keratoplasty0 510 2030 4050 60  <response>: Endothelial cell loss is a known phenomenon of endothelial keratoplasty including DSAEK.I am not sure about the answer as various studies have given different values at a different time post-operatively.First read following statements which are supporting my answer:-Current modifications of EK such as DSAEK have shown a significantly higher cell loss at just 6-12 months after DSAEK surgery.Corneal endothelial transplantReports of endothelial cell loss have been very variable from as high as 50 at 6 months to 26 after 2 years in the Busin series. Other reports suggest that there is no difference between cell loss with a 40 loss at 1 year for both PLK and PK and a recent study comparing endothelial cell loss in historic PK Vs DSAEK or other PLK techniques showed no measurable difference.Cornea External eye diseaseThe 12-month cell loss for 2 diagnoses Pseudophakicaphakic corneal edema and Fushs dystrophy was comparable, i.e. 41 and 37.InternetOne-year endothelial cell loss after DSAEK is 15 - 40 average 27.XXIV Annual Meeting European Eye Bank AssociationThere have been several publications showing endothelial cell loss to be in the range of 24-50 at 12-24 months post DSAEK. Now read the statements, which have different values at different post-operative period:The 1, 3, and 5-year endothelial cell losses derived from the models after DSAEK were 56, 66, and 73, respectively and after THPK were 24, 50 and 64 respectively. The 5-year endothelial cell loss after DSEK compared favourably with that measured after penetrating Keratoplasty in the cornea donor study 53 Vs 70.At 1-year post DSAEK, Bahar et al. published 36 cell loss, Busin et al. reported 24 cell loss; Covert and Koening published 57 and Gorovoy et al. 40. At 2 years, the rate of endothelial cell loss is between 41 Price Price and 36 Terry et al. However, amongst the given options, option c fits best in all the data mentioned above. 