<prompt> A 56-year-old man presents with a change in skin color, fatigue, and abdominal pain. He has also noticed increased urine output and thirst. On examination, his skin appears bronze in color, his liver span is 16 cm, and there is loss of body hair, and testicular atrophy. His ferritin is 600 ngmL 15-200 ngmL, aspartate amino transferase AST 130 UL 8-20 UL, alanine amino transferase ALT 150 UL 8-20 UL, and total bilirubin 0.5mgdL 0.1-1 mgdL. Coagulation tests and albumin level are normal but the random glucose is elevated at 250 mgdL. Which of the following is the most likely diagnosis?diabetes mellitus DMamyloidosisWilsons diseasehemochromatosis  <response>: High ferritin, hepatomegaly, skin changes, and diabetes suggest hemochromatosis. The arthritis is characterized by chondrocalcinosis, but, unlike idiopathic chondrocalcinosis, the hands are usually involved first. The arthropathy often progresses despite phlebotomy. Liver disease is usually the presenting feature. Skin pigmentation is predominantly by melanin. Heart failure is the most common cardiac problem. Addisons does not involve the liver, and Wilsons usually presents at an earlier age and does not cause diabetes. In amyloidosis, skin pigmentation is not a feature. 