<prompt> False about Paget disease of the nipple:Leads to destruction of whole nippleIt is an eczematous conditionAssociated with underlying carcinomaAssociated with poor prognosis  <response>: Ans: b It is an eczematous condition Ref: Bailey, 24th ed, p. 837Pagets disease of nippleIs a superficial manifestation of an underlying carcinomaDCIS or invasive ductal carcinomaIt presents as an eczema - like condition of nipple and areola, which persists despite local treatment.Nipple is eroded slowly and eventually disappears poor prognosis- Microscopy - Characterised by presence of large, ovoid cells with abundant clear, pale-staining cytoplasm in the Malpighian layer of epidermis.Eczema of nipplePaget disease of nipple- Often bilateral- Unilateral- Is often seen during lactation- Is seen at menopause- Itches- Does not itch- Vesicles present- No vesicles found- Nipple remain intact- Nipple may be destroyed- No lump felt deep to nipple- May feel a lump deep to the nipple 