<prompt> Which of the following statement is false about Hurler syndrome:X linkedMRJoint stiffnessCoarse facial features  <response>: Ans. a X linkedRef: Harrisons 17th ed. Ch.DisorderEnzymeDef:InheritanceNeurologicOphthalmo- logicHematologicUnique FeaturesHurler syndromea-L- IduronidaseARMental retardation Corneal cloudingVacuolated lymphocytesCoarse facies, cardiovascular involvement, joint stiffness, wide spaced teethHunter syndromeIduronate sulfatase ETX-linkedMental retardation, less in mild formRetinal degeneration, no corneal cloudingGranulated lymphocytesCoarse facies, cardiovascular, joint stiffness, distinctive pebbly skin lesions Both have hepatosplenomegaly and skeletal dysplasia In Hurler syndrome, death usually occurs by 10 years because of respiratory infection and heart failure. 