<prompt> Insulin-like Growth factor II plays an impoant role inControl of metablismSkeletal growthCailage growthDevolopment of foetus  <response>: The insulin-like growth factor II IGF-II internal ribosome entry site IRES is found in the 5; UTR of IGF-II leader 2 mRNA. This RNA element allows cap-independent translation of the mRNA and it is thought that this family may facilitate a continuous IGF-II production in rapidly dividing cells during development.Ref: Ganong;s review of medical physiology; 24th edition 