<prompt> A female with 45X0 genotype has primary amenorrhoea. Most likely diagnosis is:Gonadal DysgenesisAndrogen Insensitivity syndromeMeyer Rokitansky Kuster Houser Syndrome.Congenital adrenal Hyperplasia  <response>: The genotype XO belongs to the Turners syndrome which is characteristic of gonadal dysgenesis, sho stature and external and internal dysmorphic features. The gonadal dysgenesis leads to primary amenorrhea. Ref: Clinical Obstetrics and Gynaecology by Brian A. Magowan, Philip Owen, James Drife, Pages 52-53 Disorders of Sex Development By John M. Hutson, Garry L. Warne, Sonia Grover, Page 91. 