<prompt> The renal biopsy of a 6-year-old boy with recurrent gross hematuria shows IgA nephropathy. The urinary protein excretion is 130 mgday. Which of the following is the most appropriate next step in the management -Administer coicosteroidsGive AzathioprineSta CyclosporineUrinary bag sample  <response>: Ans. is a i.e., Administer coicosteroids TT of IgA nephropathy ? o There is no proven tt for IgA nephropathy. o The primary tt is proper blood pressure control. The drugs which have been proved useful are :? i Fish oil It contains omega - 3 fatty acids. It is an antiinflammatory agent and it prevents the rate of renal progression. ii Immunosuppressive therapy - It is done with coicosteroids with or without cytotoxic therapy. iii ACE inhibitors and Angiotensin II receptor antagonists - Their role in reducing proteinuria and retarding the rate of renal progression is still to be determined. iv Prophylactic antibiotics and tonsillectomy - It may reduce frequency of gross hematuria but they have no effect on progression of renal disease. 