<prompt> In Alzheimers disease, plaque is made up of:Tau proteinBeta amyloidHuntingtonAlpha synuclein  <response>: Refer: Robbins Pathologic Basis of Disease, 8thedition, pg no: 1313-1317Morphology of Alzheimers diseaseCortical atrophy especially in frontal, temporal and parietallobes.Compensatory ventricular enlargement due to loss ofparenchyma and reduced brain volume - hydrocephalus exvacuo.Structures involved early - medial temporal lobe, including hippocampus entorhinal cortex and amygdala.Progressive severe neuronal loss and reactive gliosis 