<prompt> The most serious complication of clomiphene therapy for induction of ovulation is:Bone marrow depressionHyperstimulation syndromeSecondary amenorrheaMultiple pregnancy  <response>: Ans. is b, i.e. Hyperstimulation syndromeRef: Shaw 15thed, p315Ovarian hyperstimulation syndrome is the most dreaded complication of Clomiphene. 