<prompt> Alteplase differs from streptokinase as it:Is longer actingIs derived from human kidneyIs cheapActivates plasminogen bound to fibrin  <response>: Ans. D Activates plasminogen bound to fibrinRef: KDT 8e p674Fibrinolytics are the drugs which activate plasminogen to form plasmin and thus help in lysis of thrombus. These drugs can cause bleeding as the major adverse effect due to lysis of physiological thrombi as well as due to excessive amount of plasmin generated in the circulation. 