<prompt> Congenital hea lesion s in rubella areVSDASDAoic stenosisCoarctation of aoa  <response>: Cardiac abnormalities occur in half of the children infected during the 1st 8 wk of gestation. Patent ductus aeriosus is the most frequently repoed cardiac defect followed by lesions of the pulmonary aeries and valvular disease. Reference: Nelson textbook of pediatrics 19th edition Page 1077 