<prompt> Treatment of leukoplakia isRadiationExcision and CryotherapyTopical chemotherapyRepositioning of ill fitting dentures  <response>: Management of Leukoplakia : i Many of the lesions will disappear spontaneously if the causative agent is removed.ii In lesions with higher potential for malignant change, a biopsy is taken to rule out malignancy.iii In suspicious small lesions, surgical excision or ablation with laser or cryotherapy can be done. Ref: Textbook of diseases of ENT, PL Dhingra, 7th edition, pg no. 253 