<prompt> Indication for sentinel node biopsy isNon palpable axillary lymph nodePalpable axillary lymph nodeMass 5 cmMetastasis  <response>: The first axillary node draining the breast by direct drainage is designated as the sentinel node SLN. SLN Biopsy is done in all cases of early breast cancers, T1 and T2 without clinically palpable node. It is not done in clinically palpable axillary node as there is already distoion of lymphatic flow due to tumour.I t is also not done in multifocal and multicentric tumours, as there is involvement of many lymphatic trunks from different places of breast, and chances of false-negative is high.. Ref; page no; 543 5th edition of SRB;S manual of Surgery 