<prompt> Which of the following colloid solutions has proven thromboprophylactic antithrombotic effect -GelatinDextron 40Dextron 100Hetastarch  <response>: Ans. is b i.e., Dextran 40 o Dextran 40 and 70 interferes with coagulation and platelet function and thus prolong bleeding time and so is not used in hypofibrinogenemia, thrombocytopenia or in presence of bleeding. o Dextran 40 has been tried in stroke, in DVT prophylaxis and pulmonary infarction. 