<prompt> Which of the following statements about changes in aicular cailage with aging is not TRUE?Total proteoglycan content is decreasedSynthesis of proteoglycans is decreasedTotal water content of cailage is decreasedEnzymatic degradation of proteoglycans is increased  <response>: In ageing there will be no increase in enzymatic degradation of proteoglycans. The enzymatic degradation is slow and constant throughout the life. Ref: Biology of Cailage Cells, Stockwell, R.A, 1976, 1st Edition, Page 245; Osteoahritis : A companion to Rheumatology, Elsevier, 1st Edition, 2007, Page 79. 