<prompt> Late metabolic acidosis is seen in-Term infant given formula feedPreterm baby getting cow milkLong term breast feedingNone of the above  <response>: Ans. is b i.e., Preterm baby getting cow milk Late metabolic acidosis LMA o Late metabolic acidosis is a special type of acidosis in apparently healthy premature infant. o This hyperchloremic acidosis appeares during second and third week of life, and resolves spontaneously within a couple of weeks. Definition An acidosis occuring after second day of life, in which base excess values are lower than -5meqL on two consecutive estimations done at least 24 hours apa. Etiology o Prematurity is the most impoant single predisposing factor in the development of LMA. o The incidence varies considerably depending upon the gestational maturity and protein content of feeding formula. o In preterm neonates fed on a modified cows milk the risk of developing LMA is very high. 