<prompt> The hepatotoxic octapeptides of Amanita phalloides usually produce:Massive hepatic necrosisCentrilobular zonal necrosisPeripoal injuryGranuloma formation in liver  <response>: The hepatotoxic octapeptides of Amanita phalloides usually produce massive hepatic necrosis; the lethal dose of the toxin is 10 mg, the amount found in a single death cap mushroom. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 2558. 