<prompt> The action of non-competitive muscle blockers is affected by -HypocalcemiaHyponatremiaHypehermiaAll of the above  <response>: Ans. is a i.e., Hypocalcemia Hypocalcemia has following effects It decreases vesicular ACh release at neuromuscular junction. It causes uncoupling of excitation and contraction. o By action 1. it will enhance the effect of both competitive as well as noncompetitive blockers due to unavailibility of ACh. o By action 2. it will enhance the effect of directly acting muscle relaxant dantroline. 