<prompt> In a child, non functioning kidney is best diagnosed by :Ultras onographyIVUDTPA renogramCreatinine clearance  <response>: The most convenient method of estimation of renal function is by isotope renography.Two types of isotope renography is there :1 Renogram, DTPA scan or MAG3 :DTPA and MAG3 are rapidly excreted by the kidney and are therefore used as radiopharmaceutical agents for dynamic scan.This scan is preferred for the information :i About the blood flow of kidney.ii How well each kidney is functioning.iii It there is any obstruction to urine output.2 DMSA scan :DMSA is concentrated in the renal parenchyma for a time and is therefore used as static scan.This scan is preferred to lood at structure of kidney, i.e. size, shape and position. 