<prompt> Which of the following organelles plays a pivotal role in Apoptosis:MitochondriaEndoplasmic ReticulumNucleusGolgi Apparatus  <response>: Initiation of apoptosis occurs through two different pathways, intrinsic mitochondria pathway and extrinsic death receptor mediated pathway. Mitochondria plays active role in apoptosis. Ref: Tanley L. Robbins, Ramzi S. Cotran, 2012 , Chapter 1, Cell Injury, In the book, Pocket Companion to Robbins and Cotran Pathologic Basis of Disease, 8th Edition, USA, Page 27; Robbins Basic Pathology, 7th Edition, Pages 28, 29; Essential of Apoptosis 2003, Page 245 