<prompt> Which of the following markers in the blood is the most reliable indicator of recent hepatitis Binfection?HBsAgIgG anti - HBsIgM anti - HBcIgM anti - Hbe  <response>: Answer is C IgM anti-HBc: Hbs Ag is present in recent hepatitis B infection but it is not specific to acute infection it may also be seen in carriers. IgM anti- HBc is specific for acute or recent hepatitis, and hence is the answer of choice. 