<prompt> In antibiotic associated colitis, organism involved is -Clostridium difficilePseudomonasStaphylococcusEnterococcus  <response>: Ans. is a i.e., Clostridium difficile Antibiotic - associated or clostridium difficile associated colitis o It is an example of superinfection. o It is caused by alteration of normal bowel flora, which allows multiplication of clostridium difficle which releases several toxins that damage the mucosa of the bowel and promote excretion of fluid. o It takes the form of an acute, nonspecific colitis, i.e. pseudomembranous colitis. o Almost any antimicrobial may initiate this condition, but the drugs most commonly repoed today are injectable cephalosporins and amoxiampicillin -- Laurence 9the 212 o Clindamycin, not commonly used in routine practice today, had an even greater propensity. o Metronidazole is the DOC for pseudomembranous colitis and vancomycin is an alternative. 