<prompt> Which of the following is TRUE regarding globi in a patient with lepromatous leprosy?Consists of lipid laden macrophagesConsists of activated lymphocytesConsists of macrophages filled with AFBConsists of neutrophils filled with bacteria  <response>: Acid fast mycobacterium leprae bacilli may lie extracellularly and intracellularly in large undifferentiated histiocytes known as virchows lepra cells or foamy cells. These bacilli are bounded together by lipid like substances the glia forming masses known as Globi. Because of abundant bacteria lepromatous leprosy is referred to as multibacillary. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Chapter 166 