<prompt> In complication of falciparum malaria, which drug is not given -PhenobarbitoneDexmethosoneQuinineBlood transfusion  <response>: Cerebral malariaMany adjuvant therapies have been suggested based on the prevailing pathophysiology and hypothesis of the time.These include heparin, low molecular weight dextran, urea, high dose corticosteroid, aspirn, prostacycline, pentoxifflline, desferioxamine, anti TNF antibody, cyclosporin and hyperimmune serum.Unfortunately, none have proved beneficial and several have proved harmful none of these adjuvants should be used, the cornerstone of management is good intensive care and correct antimalarial treatment.Management of cerebral malariaAntimalarial treatmentIn cerebral malaria rapidly acting parenteral drugs should be given. Quinine is the drug of choice.Fluid balanceFollowing admission patient should be rehydrated to a CVP of approximately 5 cmHypoglycemiaSlow intravenous injection of 50 dextrose waterLactic acidosisHypovolemia should be corrected firstAcute renal failureFluid should be restricted to replace insensible losses only. Dialysis should be started early when there is evidence of multiple organ dysfunction.Acute pulmonary edemaThey should be nursed upright and given oxygen and the right-sided filling pressure should be reducedBleedingLess than 5 of patients of cerebral malaria develop D.I.C. These patients should be given a fresh blood transfusion and vitamin K.Bacterial superinfection continued feverPatient with secondary pneumonia should be given empirical treatment with a third-generation cephalosporin. 