<prompt> As compared to a routine case control study, nested case control study avoids problems in study design related to -Temporal associationConfounding biasNeed for long follow upRandomization  <response>: A nested case-control NCC study is a variation of a case-control study in which cases and controls are drawn from the population in a fully enumerated coho. Usually, the exposure of interest is only measured among the cases and the selected controls. Thus the nested case-control study is more efficient than the full coho design. 