<prompt> Mesencephalo-oculo-facial-angiomatosis is seen in:KTW SyndromeNF-1 2Sturge-Weber syndromeWyburn-Mason syndrome  <response>: D i.e. Wyburn-Mason syndrome - Wyburn-Mason syndrome or Bonnet-Dechaume Blanc syndrome mesencephalo-oculo-facial or mesencephalo-optico retinal angiomatosis syndrome is characterized by neuro mesencephalo - optico oculo retinal - facial angiomatosis vascular-malformations. - Wyburn-Mason syndrome presents with telangiectasia of skinQ i.e cutaneous vascular nevi on face retinal cirsoid aneurysmQ and aerio-venous malformation AVM involving the visual pathways and midbrainQ entire optic tract optic nerve, thalamus, geniculate bodies and calcarine coex. The lesions are typically unilateral mostly. It may be aw AVMs of postrior fossa, neck, mandiblemaxilla presenting in childhood. Rendu-Osler-Weber syndrome hereditary hemorrhagic telangiectasia is AD neurocutaneous syndrome that result in a variety of systemic fibrovascular dysplasia i.e. telangiectasia, AVM, AV hemangiomafistula, and aneurysm affecting mucous membrane, skin, lung, brain and GI tract-Q. Telangiectasi is primarily found in the skin mucous membranes. AVM and fistula are found manly in liver brain lung spine. Aneurysm can invovle any size vessel. Frequent bleeding into mucous membrane, skin, lungs, genitourinary and gestrointestinal system is d t vascular weakness. Klippel-Trenaunay syndrome KTS is angio-osteo-hyperophy i.e. hyperophy of soft tissue over growth of bone IR abnormalitie of fingertoes limb and venous varicosities dt large angiomatous nevus AVM. Several KTS patients exhibit CNS findings of Sturg-Weber syndrome and are called Klippel-TrenaunayWeber syndrome. They exhibit cutaneous angiomata, soft tissue bony hyperophy and leptomeningeal vascular malformation. 