<prompt> Glucose-6-phosphate dehydrogenase deficiency causes:Megaloblastic anemiaHemolytic anemiaSickle cell anemiaMicrocytic anemia  <response>: Ans. b Hemolytic anemiaRef: Vasudevan Biochemistry, 8th ed. P 426 G6PD deficiency causes hemolytic anemia, since RBCs become susceptible to oxidative stressOther causes of hemolytic anemias are:Hemolytic anemiaIntra corpuscular Within the red cellExtra corpuscular Outside the Red CellHereditaryacquiredAuto immuneNon immune1. Warm Ab2. Cold Ab3. Transfusion reactions4. Drug associated1.Hypersplenism2. Infections Malaria3. Mechanical trauma to RBCs4. Liver disease Spur cell1. Membrane defects- Hereditary spherocytosis- Hereditary elliptocytosis- Hereditary pyro poikilocytosis- Hereditary stomatocytosis2. Enzyme defects -G6PD3. Hemoglobin defects- Hemoglobinopathiessickle cell disorders- Hb SS, CC, SC S-B-- ThalassemiasMembrane defectsPNH 