<prompt> MAC of the volatile agent is reduced in all of the following exceptElderlyAcute alcoholic intoxicationPregnancyHypernatremia  <response>: Hypernatremia causes CNS excitation thus increases MAC. Pregnancy decreases MAC because there is increase in progesterone level in pregnancy. progesterone has sedative effect on brain. age decreases MAC by 6decade Acute alchohol intoxication produce sedation thus decreases MAC 