<prompt> Gingival hypertrophy and hirsutism are the side effects of following Antiepileptic drug useDiazepamPrimidoneCarbamazepineDiphenylhydantoin  <response>: D Diphenylhydantoin Gum hypertrophy: Commonest 20 incidence, more in younger patients, can be minimized by maintaining oral hygiene. Hirsutism, coarsening of facial features troublesome in young girls, acne. Adverse effects These are numerous; some occur at therapeutic plasma concentration after prolonged use, while others are manifestation or toxicity due to overdose. At therapeutic levels Gum hypertrophy: Commonest 20 incidence, more in younger patients, can be minimized by maintaining oral hygiene. Hirsutism, coarsening of facial features troublesome in young girls, acne. Hypersensitivity reactions are--rashes, DLE, lymphadenopathy; neutropenia is rare but requires discontinuation of therapy. Megaloblastic anaemia: phenytoin decreases folate absorption and increases its excretion. Osteomalacia: phenytoin desensitizes target tissues to vitamin D and interferes with calcium metabolism. It can inhibit insulin release and cause hyperglycaemia. Used during pregnancy--can produce foetal hydantoin syndrome hypoplastic phalanges, cleft palate, hare lip, microcephaly, which is probably caused by its areneoxide metabolite. 