<prompt> Lowes syndrome is characterised by the following except-Hypophosphatamic ricketsUndescended testesDefect in the CNS and eyesAminoaciduria  <response>: Ans. is b i.e., Undescendended testes Lowes syndrome It is also known as oculocerebrorenal syndrome of Lowe. o It is X-linked disorder. It is characterized by : i Congenital cataract ii Mental retardation iii Fanconi syndrome -- Aminoacidurina o The disease is caused by mutation in the OCRL1 gene, which encodes the phosphatidylinosital polyphosphate 5-phasphatase. Clinical features Progressive growth failure Hypotonia Fanconi syndrome Significant proteinuria Blindness Renal infufficiency Behavioural problems 