<prompt> Which is the most common type of acute myeloid leukemia?M2M3M4M5  <response>: M2- AML with maturation is characterized by 20 or more myeloblasts in the blood or bone marrow and 10 or more neutrophils at different stages of maturation. M2- AML comprises approximately 30 to 45 of cases of AML. Patients frequently present with anemia,thrombocytopenia, and neutropenia. Morphologic features include the following: Myeloblasts with and without azurophilic granules. Auer rods. Promyelocytes, myelocytes, and neutrophils 10 or more of the bone marrow cells. Abnormal nuclear segmentation in neutrophils. Increased eosinophil precursors Hypercellular marrow Blasts and maturing neutrophils reactive with antibodies to MPO and lysozyme Note : Extra edge Children with Downs syndrome MC tumour : ALL MC subtype of AML : M7 subtype Drugs leading to AML Alkylating agents : 4-6 years Topoisomerase II inhibitors : 1-3 years 