<prompt> An abnormal palmar crease seen in all conditions, EXCEPT:Fetal alcohol syndromeDown syndromeCri-du chat syndromeLPAC syndrome Low phospholipid associated cholestasis  <response>: The presence of a single transverse palmar crease can be, but is not always, a symptom associated with abnormal medical conditions, such as fetal alcohol syndrome or with genetic chromosomal abnormalities, including Down syndrome chromosome 21, cri du chat syndrome chromosome 5, Klinefelter syndrome, Noonan syndrome chromosome 12, Patau syndrome chromosome 13, Edwards syndrome chromosome 18, and Aarskog-Scott syndrome X-linked recessive. A unilateral single palmar crease was also repoed in a case of chromosome 9 mutation causing multiple basal cell nevus syndrome and Robinowbrachydactyly 1 syndrome. It is also sometimes found on the hand of the affected side of patients with Poland Syndrome and craniosynostosis. LPAC is seen in families and featured by reccurent attacks of cholestatic jaundice, gallstones, biliary cirrhosis. 