<prompt> Mechanism of aspirin action isConves inactive plasminogen into active plasminInhibits COX and thus thromboxane synthesisEnhances the interaction between antitrombin III and both thrombin and the factors involved in the intrinsic clotting cascadeInhibits the glycoprotein IIbIIIa complex  <response>: Aspirin inhibits the synthesis of thromboxane A2 by irreversible acetylation of the enzyme cyclooxygenase.Other salicylates and nonsteroidal anti-inflammatory drugs also inhibit cyclooxygenase but have a shoer duration of inhibitory action because they cannot acetylate cyclooxygenase; that is, their action is reversible.Katzung 13e pg: 595 