<prompt> Treatment of metastatic disease in retinobastoma -ChemotherapyEnucleationRadiotherapyCryo  <response>: Standard dose CVE regimen for group A B C patients : 3 weekly 6 cycles of carboplastin on day 1 , vincristine on day 1 etoposide on day 1 2. High dose CVE regimen for group D: 3 weekly 6-12 cycles of the same . Ref : ak khurana 6th edition 