<prompt> Mechanism of action of aspirin is inhibition of:Thromboxane A2 synthesisPhosphodiesteraseHMG-CoA reductasePancreatic lipase  <response>: Aspirin inactivates cyclo-oxygenase by irreversible acetylation of the enzyme and thereby inhibit the synthesis of throboxane A2. From medical pharmacology padmaja 4th edition Page no 344 