<prompt> MC gene involved in endometrial carcinomaPTENBRAFKRASMismatch repair genes  <response>: PTEN - Phosphatase tensin homologue Cowden syndrome - AD disorder with tumours of skin appendages increased incidence of Breast, Endometrium, Prostate thyroid cancer Acts as TSG by serving as a break in the pro-growth PI3KAKT pathway MCly mutated pw in human ca By phosphorylating a number of substrates like BAD and MDM2, AKT enhances cell survival. 