<prompt> Mannitol is used in the management ofAcute Congestive GlaucomaCongestive Cardiac FailurePulmonary edemaAcute Renal Failure  <response>: Mannitol Mannitol, an osmotic diuretic is a drug preferred in reduction of acutely raised intraocular pressure due to Acute Congestive Glaucoma. Other agents used to relieve raised Intraocular Pressure IOP are: Glycerin, Hypeonic saline and Acetazolamide. Sho term management measures to decrease IOP - needed in acute glaucoma attacks or prepost ocular surgical procedures are met by Glycerin and Mannitol. In an acute attack of glaucoma, associated symptoms of nausea and emesis - deter the use of oral agents like glycerin - in such instances, IV Mannitol or Acetazolamide are preferred. Therapeutic Indications of Mannitol: - By IV route: - Treatment of dialysis disequilibrium syndrome Reduction of IOP in acute glaucoma and during periopeaive periods of ocular surgeries. To reduce intracranial tension associated with cerebral edema and CNS mass lesions. For treatment and prevention of acute kidney injury Enhance urinary excretion of Salicylates, Barbiturates, Bromides and Lithium following their overdose. By oral inhalation:- To diagnose bronchial hyperreactivity. Transurethral irrigation:- To prevent hemolysis during urological procedures. Use of Mannitol is contraindicated in:- CongestiveCardiac Failure, Pulmonary Edema, Renal Failure and in patients with active cranial bleeding. Ref:- Goodman Gilman Pharmacological Basis of Therapeutics 13th Ed; Pg num:-1267 