<prompt> Anakinra, used in the treatment of rheumatoid arthritis isIL-1TNF ALPHATNF BETAIL-7  <response>: A IL-1 Recombinant IL-1 receptor antagonist IL-1Ra anakinra: Inhibit IL-1 and is FDA approved for rheumatoid arthritis. Recombinant TNF-receptor-Ig fusion protein etanercept: Inhibit TNF-alfa and is FDA approved for rheumatoid arthritis, juvenile rheumatoid arthritis, psoriasis Anti-TNF-alfa monoclonal antibody: Humanized mouse chimeric MAb, infliximab Fully humanized MAb, adalimumab inhibit TNF- alfa FDA approved for rheumatoid arthritis, Crohns colitis infliximab; FDA approved for rheumatoid arthritis adalimumab. No TNF BETA inhibitors used. No IL-7 inhibitors used Anakinra is also useful in: Neonatal onset inflammatory disease, Muckle-Wells syndrome, and familial cold urticaria, Systemic juvenile onset inflammatory arthritis and adult onset Stills disease. Remember: Anakinra should not be combined with an anti-TNF drug causes high rate of serious infections. 