<prompt> All of the following are good prognostic factors for childhood Acute Lymphoblastic Leukemia, except:HyperdiploidyFemale sexPre B cell ALLt 12 : 21 translocation  <response>: Hyperdiploidy, Female sex and pre B cell ALL are associated with good prognosis. t 12 : 21 translocation may be associated with a poor prognosis and is the single answer of exclusion. Ref: Pediatric Oncology: A Comprehensive Guide By Paul Imbach, Thomas R. Kuhne, Robe Arceci, 2004, page 23. 