<prompt> Whipples triad is seen inGastrinomaInsulinomaVipomasSomatostatinoma  <response>: Insulinoma 2180, 2221-H 16th 1090-CMDT-2009 2305-6-H17thWHIPPLES TRIAD - is characteristic of hypoglycemiaI. History of hypoglycemic symptomsII. An associated fasting blood-glucose of 40 mgdl or lessIII. Immediate recovery upon administration of glucose The hypoglycemia symptoms in Insulinoma often develop in the early morning or after missing a meal Most common sites of occurrence the incidence of metastases PETs varies greatly: Jejuno-ileum 58 lungbronchus 6 rectum 4 Three phacomatoses associated with NETs are- Von Recklinghausens disease Neurofibromatosis type I- Von Hippel-Lindau disease- Tuberous sclerosis Boumevilles disease In additions to cerebellar hemangioblastomas, renal cell cancer and phaeochromocytomas, 10-17 of these patients develop a PET. Hypoglycemia unawareness is very common in patients with Insulinoma. They adapt to chronic hypoglycemia by increasing their efficiency in transporting glucose across the BBB. 