<prompt> Barretts esophagus causes which cancer:AdenocarcinomaSquamous cell CACarcinoid tumorEsophageal leiomyoma  <response>: Ans. a AdenocarcinomaRef: Harrisons 17th ed. Ch. 286 Metaplastic columnar epithelium develops during healing of erosive esophagitis with continued acid reflux since columnar epithelium is more resistant to acid- pepsin damage than is squamous epithelium. The metaplastic epithelium has different epithelial types, including goblet cells and columnar cells. Finding intestinal metaplasia with goblet cells in the esophagus is diagnostic of Barretts esophagus; this type of mucosa is thought to be at risk of cancer 