<prompt> The Electron Microscopy is viually diagnostic in renal biopsy study of -Goodpastures syndromeChurg-Strauss syndromeAlpo syndromeWegners granulomatosis  <response>: Ans. is c i.e., Alpo syndromeo Alpos syndrome presents with characteristic histological features on electron microscopy. Such changes may present in other diseases, but are most pronounced and widespread in Alpos syndrome.Features of Alpos syndrome on electron microscopy :o Alpos patients early in their disease typically have diffuse thinning of the basement membrane which thickens over time into multilamellous surrounding lucent areas that often contain granules of varying density.o The characteristic electron electron microscopic finding of fully developed disease is that glomerular basement membrane shows irregular foci of thickening alternating with attenuation thinning with pronounced splitting and lamination of lamina densa often with distinctive basket weave appearance. 