<prompt> True regarding Kaposis sarcoma?Can occur even when CD4 is normalHHV 8 is etiological agentKoebners phenomenon may be observed with itAll are true  <response>: Ans. d All are true Ref. Harrison 18th p 695KAPOSIS SARCOMA Human herpes virus type 8 is believed to be the cause of most cases of Kaposis sarcoma. There are at least four distinct epidemiologic forms of KS:- The classic form that occurs in older men of predominantly Mediterranean or eastern European Jewish backgrounds with no recognized contributing factors;- the equatorial African form that occurs in all ages, also without any recognized precipitating factors;- the form associated with organ transplantation and its attendent iatrogenic immunosuppressed state; and- the form associated with HIV-1 infection. The Koebner phenomenon has been reported to develop in classic or acquired immune deficiency syndrome-related Kaposis sarcoma.Educational points:Table: Few Important Virus Induced DiseasesGenital and anal wartsHPV 30 genital typesMononucleosis syndromeCMV, HIV, EBVHepatitisHepatitis viruses, T pallidum, CMV, EBVSquamous cell dysplasias and cancers of the cervix, anus, vulva, vagina, or penisHPV especially types 16, 18, 31, 45T cell leukemiaHTLV-IHepatocellular carcinomaHBVTropical spastic paraparesisHTLV-IB cell lymphoproliferative disease and Oral hairy leukoplakia rareEpstein-Barr virusKaposis sarcoma, body-cavity lymphomas, Primary effusion lymphoma rare, Multicentric Castlemans disease rareHuman herpesvirus type 8 HHV-8. 