<prompt> Resistance to methicllin is acquired by:Increased B-lactamase productionInduction of channels that pump out the drugAlteration in penicillin binding proteinDecreased absorption of drug in the gut  <response>: Methicillin, Nefcillin, oxacillin are B lactamse resistant penicillins. Resistance can occur only if there is alteration of penicillin binding protein. 