<prompt> Not a characteristic feature of granuloma-PMNs with fibrinoid necrosis with cellular infiltratesEpitheloid cellChronic inflammatory infiltrateGiant cell  <response>: Polymorphonuclear leucocytes or neutrophils have a major role in the acute inflammatory response. They are typically seen in acute inflammation.While granuloma formation is seen during the chronic inflammatory response.The cells predominating during chronic inflammatory response are lymphocytes, plasma cells, monocytes etc. PMNs or neutrophils are typically absent during chronic inflammation.GranulomaIt is an area of granulomatous inflammation.It consists of iActivated macrophages i.e. epitheloid cellsCells surrounding activated macrophages, these are :MonocytesLymphocytes Plasma cellsLanghans type giant cell It is a typical feature of epitheloid cell granuloma.It is derived from the fusion of macrophages and characterized by 10-50 nuclei around the periphery of the cell. 