<prompt> Feature of ApoptosisCell is enlargedKaryorrhexisPlasma membrane intactEnzymatic digestion  <response>: Features of Necrosis and ApoptosisFeatureNecrosisApoptosisCell sizeEnlarged swellingReduced shrinkageNucleusPyknosis - karyorrhexis - karyolysisFragmentation into nucleosome-sizefragmentsPlasmamembraneDisruptedIntact; altered structure,especially orientation of lipidsCellularcontentsEnzymatic digestion;may leak out of the cellIntact; may be released inapoptotic bodiesAdjacentinflammationFrequentNoPhysiologic orpathologicroleInvariably pathologicculmination ofirreversible cellinjuryOften physiologic, means ofeliminating unwanted cells;may be pathologic after someforms of cell injury, especiallyDNA damageRef: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 2; Cellular Responses to Stress and Toxic Insults: Adaptation, Injury, and Death 