<prompt> Which is the best treatment in a case of PNH presenting with black colour urine?EculizumabRituximabInfliximabPrednisolone  <response>: Ans. D. PrednisoloneTreatment:Best Initial treatment to control Hemolysis PrednisoloneBest treatment BMTBest treatment to prevent chronic hemolysis or clot formation Eculizumab:Eculizumab is a monoclonal antibody that specifically binds to the complement protein C5, thus inhibiting terminal complement mediated intravascular hemolysis in PNH patients. 