<prompt> Which of the following is not a cachetic gene?APEHMC4RSmad7Smad3  <response>: Ans is c i.e. Smad 7 o Smad 7 gene delivery prevents cachexia.o Smad-3y melanocortin - 4 receptor MC4R and APEH acylpeptide hydrolase genes have been implicated in causation of cancer cachexia. 