<prompt> Most common side effect seen with bisphosphonatesCholelithiasisConstipationErosive esophagitisOsteonecrosis  <response>: -Bisphosphonates like alendronate and risedronate are used for prophylaxis and treatment of osteoporosis. -Esophagitis is their distinctive side effect. -Precaution is to be taken while taking the drug is to take it with full glass of water and in a sitting standing position. 