<prompt> Staing point of apoptosis for programme cell death is -Activation of endonucleaseRelease of enzymeAccumulation of calciumNone  <response>: Ans. is Noneo Activation of caspases not endonuclease is central in the pathogenesis of apoptosis.A family of proteins known as caspases are typically activated in the early state of apoptosis - Anderson. o After activation of caspases, they caspases activate endonuclease.For one answer go ahead with option a, because amongst the given option only activation of endonuclease is related to pathogenesis of apoptosis. 