<prompt> All of the following increase the 2,3- DPG concentration of red cells except:-Thyroid hormonesGrowth hormoneAndrogenAcidosis  <response>: 2, 3 DPG is formed as : - Glucose inside the red cells undergo glycolysis when extra oxygen is needed, like in hypoxic conditions, glucose will be diveed to a shunt ka Rappapo Luebering cycle. And then glucose after glyceraldehyde - 3 phosphate, it will form diphosphate glycerate 2, 3 Diphosphate glycerate 2, 3 DPG. Then it combines with Hb displaces O2. Factors affecting 2,3 -DPG in 2,3-DPG in 2,3-DPG Chronic hypoxia Anemia Accilimitization Thyroid hormone Growth hormone Stored blood Acidosis But acidosis is known to inhibit glycolysis therefore acidosis is known to decrease 2, 3 DPG concentration. 