<prompt> Which of the followingg is true about Vitamin K:Vitamin K is needed for action of clotting factor VIIIVitamin K is required for bone healthVitamin K deficiency leads to DVTVitamin K is a water soluble Vitamin  <response>: Vitamin K is required for bone health. Vitamin K is involved in post translational modification of calcium binding proteins and several vitamin K-dependent proteins play an impoant role in maintaining bone and cailage health. Three most widely studies vitamin K-dependent proteins implicated in bone health are osteocalcin Bone Gla protein, Matrix Gla protein MGP and Protein S, all of these proteins undergo post-translational carboxylation of glutamic acid Gla proteins for which vitamin K is a cofactor. Vitamin K is a fat soluble Vitamin Not water soluble. Vitamin K is required in the hepatic synthesis of prothrombin an blood clotting factors II, VII, IX and X Not for clotting factor VIII. Deficiency of Vitamin K leads to delay in coagulation and bleeding disorders Not DVT Ref: Harper 