<prompt> What is the percentage of patients with disseminated discoid lupus erythematosus who develop SLE?2225282  <response>: The risk is higher in patients with disseminated DLE 22 than in DLE confined to the head and neck 1.2. Females developing DLE before the age of 40 years,with HLA-B8 in their histocompatibility type, have an increasedrisk of conveing to SLE. Neither immunological nor biochemical abnormalities appear to alter the patients progress. Note: Carpet tacktin tack sign is positive in DLE lesions. Ref: Rooks textbook of dermatology, Edition-8, Page 51.20. 