<prompt> Cystic hygroma may be associated with:Turners syndromeKlinefelters syndromeDowns syndromeAll of the above  <response>: Cystic hygroma Cystic hygromas are multiloculated cystic spaces lined by endothelial cells It results due to sequestration of a poion of jugular lymph sac from the lymphatic system Cysts are filled with clear lymph and are lined by endothelium Turners syndrome is associated with cystic hygroma Most cystic hygromas involve the lymphatic jugular sacs Cystic hygroma MC site: Posterior neck region Other common sites: Axilla, mediastinum, inguinal retroperitoneal regions Approximately 50 of them present at bih It may show spontaneous regression Clinical features Usually present at soft cystic masses that disto the surrounding anatomy, can result in acute airway obstruction. Usually manifests in the neonates or in early infancy 50 present at bih Prone to infection hemorrhage within the mass Swelling is soft paially compressible and invariably increases in size when the child coughs or cries. Characteristic features: Brilliantly translucent Diagnosis MRI play a crucial role in preoperative planning Treatment Complete surgical excision is the preferred treatment Injection of Sclerosing agents such as bleomycin or OK-432 Picibanil, derived from streptococcus pyogenes may eradicate the cystic hygroma. 