<prompt> Deficiency of GpIIb-IIIa results in which of the following condition?Glanzmann thrombastheniaWiskot Aldrich syndromeBernard Soulier syndromeNone of the above  <response>: Platelet activation by ADP triggers a conformational change in the platelet GpIIb-IIIa receptors that induces binding to fibrinogen, a large protein that forms bridging interactions between platelets that promote platelet aggregation. Predictably, inherited deficiency of GpIIb-IIIa results in a bleeding disorder Glanzmann thrombasthenia. Ref: Robbins 8th edition Chapter 4. 