<prompt> Insulin secretion is normally stimulated by -GLP-1GLP-2VIPa-adrenergic receptors  <response>: Ans. is a i.e., GLP-1 as an additional gut factor for insulin secretion and GLP-1 7-36 is more potent tnsulinotropic hormone.Regulation of insulin secretiono Factors affecting insulin secretion are : -Simulating insulin secretion :- Glucose; Mannose; Amino acids arginine, leucine; Intestinal hormones G1P, Gastrin. Secretin, CCK, GLP -1; b-keto acids; Parasympethetic stimulation acetylcholine; cAMP; b-adrenergic stimulation; theophylline; Sulfonylureas; and certain endocrine hormones like growth hormone. Glucagon and glucocorticoids.Inhibiting insulin secretion : - Somatostatin; 2-deoxyglucose; mannoheptulose; a-adrenergic stimulation, b-adrenergic inhibitors; galanin; Diazoxide; Thiazide diuretics; K- depletion; Phenytoin; Alloxan; microtubule inhibitors; and insulin itself. 