<prompt> Myeloma associated with good prognosis:t11:14deletion of 13qdel 17pt14,16  <response>: Multiple Myeloma:- Plasma cell tumor that manifest with multiple lytic bone lesion associated with pathologic fractures and hypercalcemia. Neoplastic plasma cell suppress normal humoral immunity and secrete paial Ig that are nephrotoxic Associated with diverse Translocation involving the Ig H locus, frequent dysregulation and overexpression of D cyclin. Translocation t 11:14 :- Good prognosis. 