<prompt> Which of the following statement is true regarding Fixed Dose Combination of drugsAdverse effect of one drug may be reduced by the other drugTwo drugs with different pharmacokinetics can be combined easilyDose of one drug can be altered independently as per requirementAdverse effect can be ascribed to a single drug  <response>: Fixed Drug Combination FDC Two different drug moieties are combined into a single pharmaceutical formulation. As a rule, two drugs are ideal for combination into a FDC only when they have comparable pharmacokinetics. E.g: Cotrimoxazole Sulfamethoxazole t12 -11h Trimethoprimt12 - 10h Syndopa Levodopa t12 -1.7h Carbidopa t12 -2h Ref:- HL KK Sharmas Principles of Pharmacology 3rd Ed; Pg.No: 57-8 