<prompt> most common leukemia in downsyndrome of less than 3yrs old is ?ALLAML-M5HODGKINS LYMPHOMAAML-M7  <response>: DOWNS SYNDROME : most commonly associated with ALL in less than 3 yrs old mc is AML -M7 MEGAKARYOCYTIC LUEKEMIA Clinical features Life expectancy : 55 years National Down Syndrome Society Physical appearances -- flat facial profile and an upward slant to the eye -- sho neck -- abnormally shaped ears -- white spots on the iris of the eye called Brushfield spots -- single, deep transverse crease on the palm of the hand. REF : ROBBINS 10TH ED 