<prompt> A 40 year old woman with CIN 2, next step of management?ColposcopyCyrotherapyConisationHysterectomy  <response>: Pap Class systemReagen WHO classificationRucha classificationBethesda classificationClass 1Negative for malignantNegativeWithin normal limitClass 2Inflammationsquamous atypiakoilcytes-Atypical squamous cells of unknown significanceASCUSClass 3Mild dysplasia13rd of sampleCIN1LSILClass 4Moderate dysplasia13rd to 23rd of sampleSevere dysplasia23rd of sampleCarcinoma insituCIN2,3HSILClass 5Invasive cancerInvasive cancerInvasive cancerPap smear is only a screening test. Any abnormality encountered in it should be confirmed by colposcopic biopsy.Features of abnormal pap cytologyMosaicismPunctuationsAbnormal dense nucleiGranular cytoplasmIndications for colposcopy biopsyNon visualization of the transformation zoneObvious fungation in transformation zoneMismatch between colposcopy and pap smearStage IA-1microinvasiveRefer: Shaw;s Textbook of Gynaecology, 15th edition, pg no: 402, 405 