<prompt> All are seen in reiters syndrome except?Subcutaneous nodulesOral ulcersKeratoderma blenorrhagicumCircinate balanitis  <response>: Ans. is a i.e., Subcutaneous nodules Arthropathy following a recent leisure trip suggests reactive arthritis.Eye involvement points towards Reiters syndrome.Reactive arthritis refers to acute nonpurulent arthritis, complicating an infection elsewhere in the body.Reiters syndrome is one of the classic forms of reactive arthritis i.e. an aseptic inflammatory arthritis associated with nonspecific urogenital or bowel infection with manifestations in the eye.Reactive arthritis is frequently associated with the human leucocyte antigen B27 HLA - B27 Q haplotype.The etiology of reactive arthritis remains uncertain. The most accepted theory about the pathophysiology of reactive arthritis involves initial activation by a microbial antigen followed by an autoimmune reaction that involves skin, eyes and joints.Two forms of reactive arthritis have been recognized a sexually transmitted form and a dysenteric form.Gastrointestinal infections with, shigella Q, salmonella Q and Campylobacter species and genitourinary infections with chlamydia trachomatis Q have been found to trigger reactive arthritis.The characteristic triad of Reiters syndromeArthritis Q polyarthritis, non erosiveUrethritis QConjunctivitis Q 