<prompt> All are true about splenic marginal zone lymphoma, EXCEPT:Autoimmune anemia thrombocytopenia presentThis tumor of small lymphocytes originates in the marginal zone of the spleen white pulpSplenic hilar nodes are involvedThe clinical course is virulent  <response>: Splenic Marginal Zone Lymphoma This tumor originates in the marginal zone of the spleen white pulp Tumor of small lymphocytes Splenic hilar nodes are involved The circulating tumor cells are called villous lymphocytes The cells express surface immunoglobulin and CD20 The median age of patients is fifties Patients present with incidental splenomegaly and lymphocytosis in the peripheral blood Autoimmune anemia thrombocytopenia present The clinical course of disease is indolent Long remissions after splenectomy Ref: Harrison, E-18, e-21. 