<prompt> Collagen affected in OsteogenesislmperfectaType IType IIType IIIType IV  <response>: Ans, is a i.e., Type I o Osteogenesis imperfecta also known as brittle bone disease, or Labstein syndrome is a congenital bone disorder.o People with OI are bom with defective connective tissue, or without the ability to make it, usually because of a deficiency of Type-1 collagen.o This deficiency arises from an amino acid substitution of glycine to bulkier amino acids in the collagen triple helix structure. 