<prompt> What is the drug of choice for Mycoplasma pneumoniae?PenicillinTetracyclineCefuroximeErythromycin  <response>: M. Pneumonia causes Atypical pneumonia Other organisms causing atypical pneumonia are :- 1. Mycoplasma pneumonia D.O.C -Azithromycin 2. Legionella pneumophila 3. Chlamydia pneumoniae 4. Influenza, RSV, adenovirus, Meta Pneumo virus - All these organisms are resistant to b lactams Treatment options for acute M. pneumoniae infection include Macrolides e.g., oral azithromycin, 500 mg on day 1, then 250 mgd on days 2-5,DOC Tetracyclines e.g., oral doxycycline, 100 mg twice daily for 10-14 days, and Respiratory fluoroquinolones. However, ciprofloxacin and ofloxacin are not recommended because of their high minimal inhibitory concentrations against M. pneumoniae isolates and their poor performance in experimental studies. 