<prompt> Which of the following is false?Cofactors have functions similar to those of prosthetic groups.Cofactors bind in a transient,dissociable manner to enzymesThe most common cofactors are metal ionsEnzymes that require metal ion cofactors are termed as metalloenzymes  <response>: Enzymes that require metal ion cofactor are termed metal activated enzymes,whereas enzymes for which metal ions serve as prosthetic groups are termed as metalloenzymes. If a metal is tightly bound to an enzymeprosthetic group,it is called metalloenzyme, while an enzymewithout the metal ionshowing enhanced activity on the addition pf a metal ionco factoris called as metal ion activated enzymemetal activated enzyme. Metalloenzymes:CytochromesFe,Cu,aldehyde oxidaseMo,catechol oxidasseCu,Carbonic anhydraseZn. Cofactors: A cofactor is a non protein chemical compound or metallic ion that is required for an enzymes activity. cofactor bind in a transient,dissociable manner to enzymes.Therefore,unlike associated prosthetic groups,cofactors must be present in the medium surrounding the enzyme for catalysis to occur. The most common cofactors are metal ions Reference: Harpers illustrated biochemistry 31st edition pg 58 