<prompt> A 40-year-man, working in farm, presented with headache, malaise, sense of tightness in chest, dimness of vision. On examination he had pinpoint pupils. Likely diagnosis isOP PoisoningLead PoisoningDhathura PoisoningCocaine toxicity  <response>: Ans. a OP poisoning. Ref. Parikh, textbook of FMT, 5th71, 6th813Signs SymptomsDhathura poisoningDryness of mouth throat, dysphagia, dilated pupils, dry hot skin fever, delirium, drowsiness irritability.Lead poisoningMetallic taste, dry throat, nausea vomiting, thirst, colic pain in abdomen, purging with constipation, headache, drow siness, paralysis of limbs, finally collapse precedes death.OP poisoningAffects first involuntary muscles secretory glands, then voluntary muscles, finally vital brain centers.OP PoisoningHeadache, malaise, sense of tightness in chest, diminision of vision, pin-point pupils, nausea, abdominal cramps, vomiting, diarrhea, profuse sweating, salivations and feeling of well being pleasure, due to inhibition of higher controls stage of excitement are important features. Salivation- Lacrimation Urinary incontinence --Mnemonic: SLUDGE Decreased heart rate Gastro-intestinal symptoms Elation and excessive sweating- 