<prompt> 18 year old girl with primary amenorrhea having a karyotype of 45X0 presents with infantile uterus. What should be done next?BL gonadectomyH to induce pubeyClitoroplastyVaginoplasty  <response>: Primary amenorrhea with karyotype of 45 XO with an infantile uterus is suggestive of TURNER SYNDROME Management Screen for associated abnormalities: cardiac 30 have coarctation of aoa, renal esp.horseshoe kidney, autoimmune abnormalities thyroiditis, diabetes, hypeension and hearing loss Growth hormone therapy: accelerate growth velocity and improves final height Gonadal steroids: sta with estrogen therapy and add progesterones to induce pubey 