<prompt> In Bater syndrome the defect lies in?Distal convoluted tubuleThick ascending limb of loop of HenleThin ascending limb of loop of HenleProximal convoluted tubule  <response>: Bater Syndrome- defect in thick ascending limb of loop of Henle Loss of function of Na Cl- K co transpoer Damage to ROMK Cl- channel CF: 1. Hypokalemia, salt wasting 2. Normal BP 3.Met. Alkalosis Dx: 24 hr. urine chloride : elevated 24 hr. urine Ca2 : elevated DOC: indomethacin 