<prompt> Drug of choice for actinomycosis:PenicillinSulfonamidesTetracyclineAzithromycin  <response>: 78. Ans: a Penicillin Ref: Harrisons, 16th ed, p. 939; 17th ed, p. 998Treatment of actinomycosis is intravenous administration of of penicillin 18-24 million units daily for 2- 6 weeks, followed by oral therapy with penicillin or amoxicillin total duration. 6-12 months. This is a reasonable guideline for serious infections and bulky disease. Less extensive disease, particularly that involving the oral-cervicofacial region, may be cured with a shorter course. 