<prompt> Which of the following immunosuppresive agents have a side effect of osteoporosis?CyclophosphamideMethotrexateGlucocoicoidsMycophenolate mofetil  <response>: Side effects of common Immuno-Suppresants are given below: Cyclophosphamide: Leucopenia or neutropenia, infections usually respiratory and urinary tract, infeility, cancer especially bladder cancer and leukaemia, haemorrhagic cystitis, alopecia, and amenorrhoea Glucocoicoids: Osteoporosis, candida infection oral and vaginal, other infections, weight gain, hyperglycaemia or diabetes, hypeension, cushingoid appearance, skin atrophy, and cataract Azathioprine: Nausea, leucopenia or neutropenia, infection, hypersensitivity, cancer, alopecia, cholestasis, and thrombocytopenia Methotrexate: Nausea, oral ulcers, liver dysfunction, infection, hypeension, leucopenia Mycophenolate mofetil: infection, leucopenia, gastrointestinal tract manifestations, anaemia, thrombocytopenia Rituximab: Infections encephalitis is paicularly dangerous, cancer, anaemia, neutropenia, thrombocytopenia, hypogammaglobulinaemia Ref: Diagnosis and management of ANCA associated vasculitis ; BMJ 2012;344:e26 