<prompt> Dose response relationship is a measure ofConsistency of associationStrength of associaionConsistency of associationSpecificity of association.  <response>: Ans. is b i.e., Strength of association Likehood of a causal relationship is increased by the presence of the following criteria :1. Temporal association It implies that suspected cause preceds the observed effect. It is the most important criteria.2. Strength of association It implies how strongly exposure is associated with disease. It can be determined by relative risk in cohort study, odds ratio in case-control study, dose response relationship. and cessation of exposure reversibility.3. Consistency of association The association is consistent if the results are replicated when studies in different settings and by different methods.4. Coherence of association The causal association must be coherent supported by with relevant facts.5. Specificity of association It is implies a one to one relationship. It is the weakest and the most difficult criteria to establish.6. Biological plausibility It implies biological credibility to the association, that is the association agrees with current understanding of the response of cells, tissues organs and system to stimuli. For example, positive association of food intake with GI cancer is biological plausable food enters GIT and causes cellular response, while positive association of food intake and skin cancer is not biological plausible. 