<prompt> Biotin is used in the treatment of:Multiple carboxylase deficiencyKeto acid dehydrogenase deficiencyTransketolase deficiencyMultiple dehydrogenase deficiency  <response>: Multiple carboxylasebiotinidase deficiency:- autosomal recessive disorder due to defect in holocarboxylase synthase or biotinidase deficiency. Clinical features:- -Metabolic ketoacidosis -Diffuse rash -Alopecia -Seizures -Intellectual disability 