<prompt> All of the following statements about intrinsic allergic Asthma are true, exceptNasal polypNormal IgE levelsFamily history positiveMore aggressive  <response>: These patients, with nonatopic or intrinsic asthma, usually show later onset of disease adult-onset asthma, commonly have concomitant nasal polyps, and maybe aspirin-sensitive. They usually have more severe, persistent asthma. A minority of asthmatic patients approximately 10 have negative skin tests to common inhalant allergens and normal serum concentrations of IgE. The immunopathology in bronchial biopsies and sputum appears to be identical to that found in atopic asthma.Ref: Harrisons 18e p2102, 17e p1596 