<prompt> The histology of Lobular carcinoma of breast reveals-Single file patternPleomorphic cells in sheetsClustersllslands of cells with mucous lakesSolid syncytium like sheets  <response>: Invasive lobular carcinoma consists of cells morphologically identical to the cells of LCIS. Two thirds of the cases are associated with adjacent LCIS. The cells invade individually into stroma and are often aligned in single-file strands or chains. This growth pattern correlates with the presence of mutations that abrogate the function of E-cadherin, a surface protein that contributes to the cohesion of normal breast epithelial cells. ref : Robbins Basic Pathology, 9E,page-711 REF of IMG : 