<prompt> A patient suffering from AIDS is on Zidovudine, Lamivudine, Indinavir therapy, He develops pulmonary tuberculosis for which treatment is staed. Which of the following should be avoided in himINHEthambutolPyrazinamideRifampicin  <response>: Refer KDT 6e p 741 Rifamipicin is a powerful enzyme inducer. It increases the metabolism of protease inhibitors and thus decreases the efficacy of anti retroviral therapy another drug, rifabutin is devoid of these interactions and is the preferred agent for treatment of mycobacterial infections in patients 