<prompt> Antiemetic effect of Metoclopromide is mainly due to its action as5HT3 antagonistD2 antagonistM3 antagonist5HT4 agonist  <response>: Antiemetic effect of Metoclopramide is because of D2 antagonism 5HT3 antagonism.Prokinetic effect is due to 5HT4 agonism. 