<prompt> Tumor marker for primary hepatocellular carcinoma are all exceptAlpha feto proteinAlpha 2 macroglobulinPIVKA-2Neurotension  <response>: Tumor markers for Hepatocellular carcinoma Protein induced by Vitamin K absence PIVKA;Des-gamma-carboxy prothrombin ;glypican-3 ; AFP fractions Lectin fraction-3 of AFP AFP-L3 is highly specific to HCC and also an indicator of poorly differentiated histology and unourable prognosis Serum AFP level is elevated above 20 ngml in 70 of patients with HCC Monoclonal antibody HepPar-1 hepatocyte paraffin - 1 identifies a unique antigen on hepatocyte mitochondria and is used to identify hepatocytes or HCC Ref : Sabiston 20th edition Pgno : 1458-1463 