<prompt> Not true about gynecomastia isCan be drug inducedKlinefelters syndromeSeen in cryptoorchidismNone of the above  <response>: Gynaecomastia is hypertrophy of male breast more than usual due to increase in ductal epithelial and connective tissue stromal elements often attaining features of the female breast. It can be unilateral or bilateral. Bilateral can be symmetrical or asymmetrical.Etiology is Oestrogen excessincreased estradiol secretion due to a testicular tumour Leydig cell or nontesticular tumours from the adrenal cortex, lung, liver; hyperthyroidism increases conversion of androgen to estrogen, liver diseases, oestrogen therapy for prostate cancer.Androgen deficiencyaging, KlinefeltersKallmann syndromes, a eunuch, ACTH deficiency. Secondary testicular failurecryptorchidism, orchitis, trauma, CRF, etc. Drugs 25: Increases estrogen activity digitalis, anabolic steroidestrogen synthesis reserpine, theophylline, frusemide. Inhibition of testosterone synthesiscimetidine, phenytoin, spironolactone. 