<prompt> Haldane effectEffect of 2,3 -BPGDissociation of CO2 on oxygenationDissociation of O2 on addition of CO2Chloride shift  <response>: Because deoxyhemoglobin binds more H than oxyhemoglobin does and forms carbamino compounds more readily, binding of O2 to hemoglobin reduces its affinity for CO2 Haldane effect.Ref: Ganong review of medical physiology 23rd edition Page no: 612 