<prompt> Most common type of human papilloma virus causing Ca cervix are:16 and 181 and 336 and 112 and 14  <response>: It is now established that HPV plays a major role in cervical carcinogenesis.Among the various genotypes more than 100 the Genotype of HPV which is:Most commonly associated with squamous cell carcinoma cervix - HPV 16Most common genotype associated with adenocarcinoma of cervix - HPV 18Overall MC genotype associated with invasive carcinoma, CIN II and CIN III - HPV 16But HPV 16 is not very specific as it is seen in 16 of women with low grade lesion and 14 women with normal cytology so: - HPV 18Most specific genotype of HPV for invasive tumor The cytological changes caused by HPV are collectively called as Koilocytosis.In most of the females HPV infection clears in 9-15 months , only in small minority it persists.Malignant transformation requires expression of E6 and E7 HPV oncoproteins. 