<prompt> First clinical sign of vitamin A deficiency -Poor growthConjunctival xerosisHydrocephalusPhrynoderma  <response>: Ans. is b i.e., Conjuncival xerosis The most characteristic and specific sign of vitamin-A deficiency are eye lesions. The term xerophthalmia dry eye comprises all ocular manifestations of vitamin-A deficiency. It has following stages1 Night blindness earliest symptom2 Conjunctival xerosis earliest sign3 Bitots spot4 Corneal xerosis5 Corneal ulcer keratomalacia. 