<prompt> Action of Papain on an IgG molecule produces?2 Fc fragments 1 Fab fragment1 Fc fragment 2 Fab fragments2 Fc fragments 2 Fab fragments1 Fc fragment 1 Fab fragment  <response>: 1 Fc fragment 2 Fab fragments REF: Jawetz, Melnick, Adelbergs Medical Microbiology, 24TH edition Chapter 44 If an antibody molecule is treated with a proteolytic enzyme eg, Papain, peptide bonds in the hinge region are broken. This breakage produces two identical Fab fragments, which carry the antigen-binding sites, and one Fc fragment, which is involved in placental transfer, complement fixation, attachment for various cells, and other biologic activities. 