<prompt> Hyperuricemia is caused in newborn due to defect in:Adenosine deaminaseOrnithine transcarbamylaseXanthine oxidaseHypoxanthine guanine ribosyltransferase  <response>: Plasma uric acid is elevated in Lesch Nyhan disease Hypoxanthine guanine ribosyltransferase deficiency Xanthine oxidase deficiency- plasma uric acid Adenosine deaminase deficiency leads to hypouricemia. Ornithine transcarbamylase deficiency- ammonia 