<prompt> Which of the following HLA subtype is most characteristically associated with Rheumatoid ahritis:HLADR1HLADR2HLADR3HLADR4  <response>: Answer is D HLA-DR4: Rheumatoid ahritis is associated with multiple HLA-DR subtypes, but the strongest association has been repoed with HLA DR4 The class II MHC allele HLA DR4 and related alleles are knkwn to be major genetic risk factors for RA - Harrison HLA and Rheumatoid Ahirits Rheumatoid Ahritis is strongly associated with specific HLA class II markers Rheumatoid Ahritis is only weakly associated with HLA class I marker Rheumatoid Ahritis is associated with multiple HLA subtype encoded by the HLADRB 1 gene Multiple HLA subtypes that are associated with RA HLA DRB1 gene HLA DR4 strongest association in general HLA DR 1 HLA DR 6 HLA DR 9 HLA DR 10 HLA DR 14 In different ethnic groups HLA DR1, HLA DR4, HLA DR6, HLA DR9, HLA-DR 10, HLA DR-14 molecules have been associated with RA. Ceain HLA DR alleles may protect against development of RA. HLADR Alleles that may protect against development of RA HLA DR 2 HLA DR 3 HLA DR 5 HLA DR 7 