<prompt> All of the following statements about insulin like growth factor -IGF are true, except2018Mainly secreted by the pancreasAlso known as somatomedin CSecretion is stimulated by growth hormoneRequired for skeletal and cailage growth  <response>: Gene for IGF is expressed in the choroid plexus and meninges,cailage, Liver and in many other tissues, indicating that they are likely synthesized in these tissues. Secretion of IGF-I is independent of growth hormone before bih but is stimulated by growth hormone after bih. Growth hormone acts on cailage to conve stem cells into cells that respond to IGF-I,Locally produced as well as circulating IGF-I then makes the cailage grow. Insulin like growth factors are also known as Somatomedin C.. Ref:-Ganong, pg num:-327 