<prompt> Most common cause of nephrotic syndrome in children-Membranous GNMinimal change diseasePSGNRPGN  <response>: Ans. is b i.e., Minimal change disease Most common cause of Nephrotic syndromei In adults-Membranous glomerulonephritisii In children-Minimal change disease lipoid nephrosis Causes of Nephrotic syndromeI. Primary GlomerulonephritisV Malignancy1. Minimal change disease most common in children1. Carcinomas2. Membranous GN most common in adults2. Myeloma3. Membranoproliferative GN3. Hodgkins disease4. Focal segmental glomerulosclerosisVI Pregnancy5. Focal GNToxaemia of pregnancy6. IgA nephropathyVII Circulatory DisturbancesII Systemic diseases1. Renal vein thrombosis1. Diabetes mellitus2. Constrictive pericarditis2. AmyloidosisVIII.Hereditary diseases3. SLE1. Alports diseaseIII Systemic Infections2. Fabrys disease1. Viral infections HBV, HCV, HIV3. Nail-patella syndrome2. Bacterial infections bacterial endocarditis, syphilis, leprosy 3. Protozoa and parasites P. falciparum malaria, filariasis IV Hypersensitivity Reactions 1. Drugs heavy metal compounds like gold and mercury, other drugs like penicillamine, trimethadione and tolbutamide, heroin addiction 2. Bee stings, snake bite, poison ivy 