<prompt> The following statements are true regarding Chlamydia except:Erthromycin is effective for therapy of Chamydial infectionsTheir cell wall lacks a peptidoglycan layerThey can grow in cell free culture mediaThey are obligate intracellular bacteria  <response>: Unique properties of Chlamydia areChlamydia is an obligate intracellular parasite. This means they can survive only by establishing residence insideAnimal cellsThey need their hosts ATP as an energy source for their own cellular activity. They are energy parasites using aCell membrane transport system that uses ATP from the host system and gives out ADP.This obligate intracellular existence makes it impossible to culture these organisms on nonliving artibacterial media.Due to their small size and failure to grow in cell - free media they were considered to be viruses.Chlamydiae grows in cultures of a variety of eukaryotic cell lines Me Coy or HeLa cells. It may be necessary toTreat cells with poly anionic compounds such as DEAD-dextran to reduce the electrostatic barrier to infection.Antimetabolite such as cycloheximide is added to favour competition for host cell amino acid pools. All types ofChlamydiae proliferate in embryonated eggs particularly in the yolk sac.The special features in structure and chemical composition of chlamydiae areThe outer cell wall resembles the cell wall of gram negative bacteria It has a relatively high lipid contentIt is rigid but it does not contain typical bacterial peptidoglycan; perhaps it contains a Tetrapeptide linked matrix.N Acetyl muramic acid also appears to be absent from chlamydiae cell wallAntibiotic susceptibility of chlamydiae.Penicillin binding proteins occur in chlamydiae cell wall and chlamydiae cell wall formation is inhibited by penicillinsAnd other drugs that inhibit transpeptidation of bacterial peptidoglycan. But remember the important point about tt,That cell wall inhibitors result in the production of morphologically defective forms but are not effective in clinicalDisease. Inhibitors of protein synthesis tetracyclines, erythromycins are effective in most clinical infections. ErythromycinOr tetracyclines are considered the drug of choice for chlamydiae infections. 