<prompt> Syndrome associated with increased risk of leukemia is:Plummer Vinson syndromeKlinefelter syndromeSturge Weber syndromeMultiple hamartoma sydrome  <response>: Genetic disease association of Lympho-haematopoietic malignancies:Acute leukaemia occurs with increased frequency with a variety of congenital disorders such as:Downs syndromeBlooms syndromeKlinefelters syndromeWiskott-Aldrichs syndromeMohan H. Textbook of pathology. Jaypee Brothers Medical Publishers; 2015. Edition 7. Page 334 