<prompt> All are true about Gilberts Syndrome Except -Mild conjugated hyper bilirubinemiaAutosomal dominantNormal liver histologyAlmost normal liver function  <response>: Ans-AGilbert syndrome causes unconjugated hyperbilirubinemia.Gilberts syndrome is an autosomal dominant disorder.Characteristic features are :Mild unconjugated hyperbilirubinemia due to:Decreased hepatic uptake of bilirubinDecreased activity of uridyl glucuronyl transferase causing defective conjugation.Standard hepatic biochemical tests are normal.Normal hepatic histology.Gilberts syndrome is a type of congenital hyperbilirubinemia.Other types of congenital hyperbilirubinemia.Crigler Najjar Type I-The complete absence of the enzyme - UDP glucuronyl transferase.Causes severe jaundice, death in early life.Unconjugated hyperbilirubinemia Type II- Partial absence of enzyme.Dubin-Johnson-a defect in excretion of conjugated bilirubin, therefore, causes conjugated hyperbilirubinemia.Rotors syndrome Same as Dubin-Johnson. Note :The difference between Dubin-Johnson and Rotors Syndrome.In Dubin-Johnson there is an accumulation of pigment in the hepatocytes, imparting a brown or black color to the liver.Mnemonic - Michael Johnson is black 