<prompt> Central nervous system manifestion in chronic renal failure are a result of all of the following except -HyperosmolarityHyperparathyroidisnAcidosisHyponatremia  <response>: Chronic renal failure results in- Sodium and water retention leading to hyponatremianot common and responds to water restriction. Decreased ca absorption -Hypocalcemia-increase in PTH -Hyperphosphatemia,increased bone resorption resulting in hypercalcemia-deposition of calcium in extraosseous sites such as vascular bed and soft tissues. Hyperkalemia Hyperchloremic metabolic acidosis is present in early stages of ckd1-3. Ref:HARRISON 20 th edition pg no. 2114,2115 