<prompt> CA-125 is a marker antigen for the screening of the following malignancy:Prostate cancerBreast cancerBrain cancerOvarian cancer  <response>: CA125 is a glycoprotein that is not produced by normal ovarian epithelium, but may be produced by both benign and malignant ovarian tumors. Most commonly, cancer antigen 125 CA125 level measurements andor transvaginal sonography have been used for screening of ovarian tumors in suspected individuals. Ref: Hoffman B.L., Schorge J.O., Schaffer J.I., Halvorson L.M., Bradshaw K.D., Cunningham F.G., Calver L.E. 2012. Chapter 35. Epithelial Ovarian Cancer. In B.L. Hoffman, J.O. Schorge, J.I. Schaffer, L.M. Halvorson, K.D. Bradshaw, F.G. Cunningham, L.E. Calver Eds, Williams Gynecology, 2e. 