<prompt> Therapeutic index is a measure of?EfficacyAdverse effectsSafetyPotency  <response>: ANSWER: C Safety REF: KDT 7th ed p, 5455Therapeutic index Median lethal doseMedian effective doseOne estimate of a drugs margin of safety is the ratio LD50ED50, the therapeutic index, which is a statement of how selective the drug is in producing its desired versus its adverse effects. 