<prompt> Apoptosis causes all except:Activation of caspaseLocal inflammatory responseCondensation of chromatinCleavage of chromatin by endonucleases  <response>: Features of Necrosis and Apoptosis Necrosis Apoptosis Always pathological May be physiological or pathological Associated with disruption of cellular homeostasis e.g. ischemia, hypoxia poisoning Impoant for development, homeostasis elimination of pathogens tumor cells Affects contiguous adjacent group of cells Affect single cells Cell size is increased Cell size is shrunken Passive Active Causes inflammatory reaction No inflammatory reaction Plasma membrane is disrupted Plasma membrane is not disrupted Smear pattern on electrophoresis Step ladder pattern on electrophoresis 