<prompt> A 4 year old female child complains of weakness and pain in joints. Her parents are known case of sickle cell trait. Hb electrophoresis reveal HbS pattern. This disease occurs because of which base alteration?CTC CAC in DNAGAG GUG in DNACTC CAC in RNAGAG CAC in RNA  <response>: The occurrence of the disease sickle-cell anemia due to a single base alteration CTC CAC in DNA, and GAG GUG in RNA is a classical example of the seriousness of mutations.Satyanarayana- Biochemistry, 3rd edition, pg-549 