<prompt> The therapeutic efficiency of antihypeensive drugs is blunted by NSAIDs because theyCause of sodium excretionIncrease the clearance of anti Hypeensive drugsDecrease the absorption of antihypeensive drugsDecrease the synthesis of Vascular prostacyclin  <response>: PG E2 and PGI2 cause renal vasodilatation, natriuresis and increased water clearance due to inhibition of the action of ADH. Loop diuretics act paly by increasing the stimulation of cox. therefore NSAIDs attenuate the diabetic action of these drugs. Refer kDT 6e p708 