<prompt> A thiy year man presented with nausea, fever and jaundice of 5 days duration. The biochemical tests revealed a bilirubin of 6.7 mgdl conjugated 5.0 mgdl with SGOTSGPT ASTALT of 1230900 IUml. The serological tests showed presence of HBsAg, IgM anti HBc and HBe Ag. The most likely diagnosis -Chronic hepatitis B infection with high infectivityAcute hepatitis B infection with high infectivityChronic hepatitis B infection with low infectivityAcute hepatitis B infection with low infectivity  <response>: HBs Ag is the first marker appear in the blood after infection. Anti-HBc is the earliest antibody seen in blood.HBeAg indicates infectivity REF:MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.546547 