<prompt> Alpha 2 agonists cause all of the following except:AnalgesiaHyperalgesiaSedationAnxiolysis  <response>: Ans. B HyperalgesiaRef: Goodman and Gilman 12th296; Katzung 12th176; KDT 8the p140 Alpha 2 agonists cause analgesia, not the hyperalgesia. Clonidine is used for treatment of hypertension. It decreases blood pressure by acting on central alpha 2 adrenergic receptors. Dexmedetomidine is another alpha 2 receptor agonist that is used to produce sedation and anxiolytic state by action on alpha 2 receptors in the brain. It can also produce analgesia by acting on alpha 2 receptors in spinal cord. 