<prompt> Closure of the anterior fontanelle is delayed in all exceptDowns syndromeOsteogenesis imperfectaHypogonadismHypothyroidism  <response>: Delayed closure of anterior fontanel wide large anterior fontanelThe anterior fontanel nonnally closes between 12 to 18 months of age.The presence of excessively large anterior fontanel and its delayed closure is a recognised clinical feature in following conditions. 