<prompt> Best method of estimation of amount of proteinuria in a 2 year child with nephrotic syndrome is?Dipstick testing24 hr urine proteinSingle morning spot urine sample for proteincreatinine ratioMicroalbuminuria  <response>: Best method of estimation is- Single morning spot urine sample for proteincreatinine ratio 24 hr urine protein: Difficult to collect urine sample in children Normal value 100 mgm224 hr Spot urine sample for proteincreatinine ratio: Simplest method to quantitate proteinuria Normal value below 0.2; a ratio of 0.2-2 indicates mild to moderate proteinuria and 2 indicates heavy proteinuria. Dipstick testing: False-positive test can occur if urine is very alkaline pH 8.0 or very concentrated specific gravity: 1.025 