<prompt> Genetic expression of Na KATPAse inducible by-AldosteroneCortisolThyroxineACTH  <response>: Ans. is a i.e.. Aldosterone Mineralocorticoid actionso The principal mineralocorticoid secreted by adrenal cortex is aldosterone.o The main action of aldosterone is to enhance Na reabsorption in the distal convoluted tubule in kidney.o There is an associated increase in K and H excretion.Excess mineralocorticoid - Na and water retention Hypertension edema, Hypokalemia, Alkalosis.Mineralocorticoid deficiency Addisons disease - Hyperkalemia. Acidosis, Hypotension,o Mechanism of actionMineralocorticoid acts on cytoplasmic receptors.It increases transcription of m.RNA in renal tubular cells to symthesis Aldosterone - induced protein ATP which is Na K ATPase.Symthesis of b-subunit of amiloride sensitive Na channel is also induced. 