<prompt> All of the following factors are produced by hepatocytes exceptFibrinogenProthrombinVon willebrand factorFactor VIII  <response>: Von Willebrand factor large- 20,000 kD multimeric molecule composed of - 200 kD monomers, synthesized by vascular endothelium, megakaryocytes, and platelets; vWFs hemostatic efficiency is related to multimer size.Ref: Ganong;s review of medical physiology 23rd edition Page no: 532 