<prompt> Cafe au lait macules are seen inVon Reklinghausens neurofibromatosisAlbrights syndrome and Blooms syndromeAll of the aboveNone of the above  <response>: Bloom syndrome is characterized by a high frequency of breaks and rearrangements in an affected persons chromosomes. The affected person characteristically develops a facial rash after exposure to sun. Other clinical features include a high pitched voice, distinct facial features such as Long, narrow face, micrognathism of mandible, and pigmentation changes of skin with cafe aulait spots. 