<prompt> Anticentromere antibodies are most commonly associated withDiffuse cutaneous systemic sclerosisMixed connective tissue diseaseCREST syndromePolymyositis  <response>: The constellation of calcinosis cutis, Raynauds phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia, was historically termed the CREST syndrome . Anti-centromere antibodies ACAs; often styled solid, anticentromere are autoantibodies specific to centromere and kinetochore function. They occur in some autoimmune diseases, frequently in limited systemic scleroderma formerly called CREST syndrome, and occasionally in the diffuse form of scleroderma. Ref - HArrisons 20e p2546 