<prompt> Loading dose is given for which of the following drugDiazepamPropranololChloroquineAspirin  <response>: Chloroquine is a drug having maximum Volume of Distribution Vd 1300 L. This means it is mostly distributed in the tissues whereas the main site of its pharmacological action is RBCs. Therefore, it is given as a loading dose to attain steady state plasma concentration quickly. Chloroquine is a synthetic 4-aminoquinoline that has been the mainstay of antimalarial therapy, is the drug of choice in the treatment of erythrocytic P. falciparum malaria, except in resistant strains. 