<prompt> Which of the following eicosanoids cause vasoconstriction as well as increase vascular permeability?ProstacyclinThromboxane A2PGE1Leukotriene C4  <response>: Principal Inflammatory Actions of Arachidonic Acid Metabolites Eicosanoids ACTION EICOSANOIDS Vasodilation PGI2 prostacyclin, PGE1, PGE2, PGD2 Vasoconstriction Thromboxane A2, leukotrienes C4, D4, E4 Increased vascular permeability Leukotrienes C4, D4, E4 Ref: Robbins 8th edition Chapter 2. 