<prompt> Corkscrew esophagus is seen in which of the following conditions?Carcinoma esophagusSclerodermaAchalasia cardiaDiffuse esophageal spasm  <response>: Ans. d Diffuse esophagus spasmRef Sabiston 20th edition, Pages 1015-1018 Salient Points in DES: Most common in women Achalasia - Equal High amplitude repetitive contraction Achalasia - Low Amplitude Chest pain and dysphagia Cork screw appearance Gold standard - Manometry Main stay of management is Nonsurgical and medical with nitrates and CCB Long esophagomyotomy is for failed cases and cases with epiphrenic diverticulumSalient Points in Nut cracker esophagus: Super squeeze esophagus MC and Most painful hypermotility disorder. Medical management is the only option. 