<prompt> Classical markers for Hodgkin;s disease isCD 15 and CD 30CD 15 and CD 22CD 15 and CD 20CD 20 and CD 30  <response>: Reed Sternberg cells in all types of Hodgkin;s diseases, except in lymphocytic prdominance type,express immunoreactivity for CD 15 CD 30. RS cells in lymphocytic predominance type are negative for both CD 15 CD 30, but positive for CD 20.Reference : Harsh mohan textbook of pathology 6th edition pg no370 