<prompt> Most common ovarian tumor is?Germ cell tumourEpithelial tumourSex cord tumourTeratoma  <response>: ANSWER: B Epithelial tumourREF: Novaks 14th ed ch 35 pg 1461See APPENDIX-59 for MAJOR HISTOPATHOLOGIC CATEGORIES OF OVARIANCANCERRepeat 2012 Session 2 Different options APPENDIX - 59Major Histopathologic Categories of Ovarian CancerGroupTypeLateralityAlso knowEpithelialNeoplasms60 of all ovarian neoplasmsserouscystadenocarcinoma75-80- of all epithelial cancersBilateral in 40-60 of casesmost common malignant tumor of the ovary Psammoma bodies,Mucinous neoplasms10 of all epithelial ovarian tumorsBilateral in less than 10 of cases.Pseudomyxoma peritonei,Endometrioidneoplasms10 of epithelial tumorsBilateral in 30-50 of casesresembles endometrial adenocarcinomaClear cell carcinoma meso nephroid carcinomaless than 1 of epithelial ovarian cancers Two cell types; clear cell hobnail cellTransitional cell Brenner carcinoma 1 of epithelial cancers resemble low-grade transitional cell carcinoma of the urinary bladderUndifferentiatedcarcinoma 10 of epithelial neoplasms. absence of any distinguishing microscopic featuresGerm Cell NeoplasmsDysgermlnoma30-40 of germ cell tumorsunilateral in 85-90 of casesfemale counterpart of the seminomaEndodermal sinus tumor yolk sac tumor3rd most common germ cell neoplasmBilateral in nearly 100 of casesSchiller-Duval bodyAFP Immature teratoma2nd most common germ cell malignancyBilateral in less than 5 of casesAFP Mature teratoma or dermoid most common neoplasm diagnosed during pregnancyEmbryonal carcinomavery rare HCGAFPChoriocarcinomarare AFP - HCGGonadoblastomarare Rt ovary left ovary, Associated with presence of Y chromosomeMixed germ cell tumors10 of germ cell j neoplasms Dysgerminoma endodermal sinus tumor most commonPolyembryomaextremely rare Embryoid bodiesAFP and HCG Sex cord- stromal tumors 5-8 of all ovarian tumorsAll are estrogen producing hirsutismGranulosa cell tumors70 of sex cord stromal tumors CaJl-Exner bodiesThecoma ExclusivelyunilateralExclusively benignSertoli-Leydig cell tumorsRareRarely bilateral GynandroblastomaRare Both ovarian granulosa theca testicular Sertoli Leydig cellsMetastatic5-6 of all ovarian malignanciesKrukenberg Tumor eponyrn is used to denote any GI carcinoma metastatic to the ovary, mostly stomach carcinoma.The primary ovarian tumor stain positive for cytokeratin 7 CK7 negative for CK20. While metastatic lesion is CK7 negative, CK20 positive. 