<prompt> A 62-year-old man is brought to the emergency room in a disoriented state. Physical examination reveals jaundice, splenomegaly, and ascites. Serum levels of ALT, AST, alkaline phosphatase, and bilirubin are all elevated. A liver biopsy demonstrates alcoholic hepatitis with Mallory bodies. These cytoplasmic structures are composed of interwoven bundles of which of the following proteins?a1-Antitrypsinb-Amyloid AbIntermediate filamentsPrion protein PrP  <response>: Intermediate filaments -Hyaline is a term that refers to any material that exhibits a reddish, homogeneous appearance when stained with hematoxylin and eosin HE. -Standard terminology includes:- Hyaline aeriolosclerosis Alcoholic hyaline in the liver Hyaline membranes in the lung Hyaline droplets in various cells. -Alcoholic Mallory hyaline is composed of cytoskeletal intermediate filaments cytokeratins -Pulmonary hyaline membranes consist of plasma proteins deposited in alveoli. -Structurally abnormal a1-antitrypsin molecules choice A accumulate in the liver of patients with a1-antitrypsin deficiency. -a-Synuclein accumulates in neurons in the substantia nigra of patients with Parkinsons disease. Diagnosis: Alcoholic liver disease Prions contain infectious proteins devoid of RNA or DNA- CJD Creutzfeldt-Jakob disease Infective prions have misfolded proteins alpha helix to beta sheet 