<prompt> A patient with AIDS and a CD4 cell count of 100ml, has a persistent fever and a weight loss associated with invasive pulmonary disease due to M avium complex. Optimal management of this case requires:Select an antibiotic regimen based on drug susceptibility of the cultured organismSta treatment with isoniazid and rifampicinTreat the patient with clarithromycin, ethambutol and rifabutinTreat with trimethoprim sulfamethoxazole  <response>: Mycobacterium avium complex infection is treated with combination of rifabutin, ethambutol and clarithromycin. REC These drugs are given once daily. Clarithromycin can be replaced with azithromycin which is long acting and can be administered once a week. 