<prompt> False about sustained release tablets -Release drug at a constant rateLess chances of toxicityContain large amount of drugMargin of safety is an important consideration  <response>: Ans. is b i.e., Less chances of toxicity o A sustained-release dosage form provides an initial amount of drug sufficient to produce a desired therapeutic plasma concentration and continuously releases the drug at a constant zero-order rate which will maintain the therapeutic concentration for an extended period recommended dosage interval. The margin of safety of the drug active ingredient is an important consideration in the selection of a candidate drug, because sustained-release products contain a large amount of the drug and the possibility of dosedumping with resultant toxicity exists. 