<prompt> Regarding Candida true are -Commensal in skinOral candidiasis common in pregnancyIn AIDS at early stageGrams Staining done . .  <response>: Candidiasis thrush Superficial candidiasis is caused by Candida spp., mainly C. albicans. Manifestations include oropharyngeal and vaginal candidiasis thrush, interigo and chronic paronychia. Superficial candidiasis often follows antibiotic therapy. Interigo is characterised by inflammation in skin folds with surroundingsatellite lesions. Chronic paronychia is associated with frequent wetting of the hands. Superficial candidiasis is treated mainly with topical azoles , oral azoles being reserved for refractory or recurrent disease. Severe oropharyngeal and oesophageal candidiasis is a consequence of CD4 T-lymphocyte depletion dysfunction, as in HIV infection . Recurrent vaginal or penile candidiasis may be a manifestation of diabetes mellitus. Rarely, mutations in the autoimmune regulator gene AIRE or signal transducer and activator of transcription 1 STAT1 cause a syndrome of chronic mucocutaneous candidiasis . This is characterised by Candida infections of skin, mucosa and nails, with hyperkeratotic nails and erythematous periungual skin. Patients have cell-mediated immune defects against Candida and may have polyendocrinopathy and autoimmune features. Ref Harrison20th edition pg 1127 