<prompt> In acute liver injury-ASTALT ratio 1 occur in most of the hepatocellular conditionsASTALT ratio 2:1 suggestive of alcoholic liver diseaseSynthesis ofAST is inhibite by ethanolIn alcoholic liver disease ASTALT ratio 1  <response>: ASTALT ratio.. Most causes of liver cell injury are associated with a greater increase in ALT than AST; however, an AST to ALT ratio of 2:1 or greater is suggestive of alcoholic liver disease, paicularly in the setting of an elevated gamma-glutamyl transferase. Ref Davidson edition23rd pg 852 