<prompt> All of the following are modes to decrease pain on injection caused by propofol cxceptMix lignocaine with propofolGive fentanyl prior to propofoUse vein on the dorsum of handCooling of the drug  <response>: Propofol is formulated as a lipid emulsion which causes pain during injection that can be decreased by using a large vein, avoiding veins in the dorsum of the hand, prior injection of lidocaine or by mixing lidocaine with propofol prior to injection 2 mL of 1 lidocaine in 18 mL propofol. prior injection of opioid Thicker vein decreases pain on injection caused by propofol. 