<prompt> Chemotherapy for choriocarcinoma. DOC is-MethotrexateCyclophosphamideCisplatinDoxorubicin  <response>: Ans. is a i.e., Methotrexate Chemotherapy in molar pregnancyIndicationso If the hCG level fails to become normal in stipulated time 10-12 weeks or re-elevates after 4-8 weeks.o Rising ji-hCG level, once it reached normal,o Post evacuation haemorrhageo Where followr up facilities are not adequateo Evidence of metastasis irrespective of hCG levelso Risk of malignancy is highChemotherapyo Methotrexate 1 mgkgday is given iv or im on day 1,3,5 7 with folinic acid . 1 mgkg on days 2,4,6 8. It is to be repeated every 7 days. A total of 3 courses are given,o Alternatively, intravenous actinomycin-D 12 mcgkgday is given for 5 days. It is less toxic. 