<prompt> A major source of Von Willebrand factor vWF -ErythrocytesNeutrophilsEndothelial cellsMonocytes  <response>: Circulating factor VIII has two components.a Factor VIII c Procoagulant proteinThis is the smaller componentIt is synthesized in the liver main source and kidney.It is an intrinsic pathway component required for activation of factor X.b Von willebrand factor vWFThis is the larger componentIt is produced by endothelial cells main source and megakaryocytes.It has two major functions.Helps in platelet adhesion by interacting platelet membrane glycoprotein Ib-IX.Stabilizes factor VIIIc. 