<prompt> Warfarin to be stopped__ days before surgery2 to 3 days4 to 5 days6 to days8 to 9 days  <response>: Warfarin should be stopped 4 to 5 days before surgery. clinical implication : to replenish coagulation factors. Monitor PT with INR , aPTT,ACT. In emergency cases, give Inj.vitamin K., if bleeding continues give FFP,croprecipitate transfusions. 