<prompt> The type of hemoglobin that has least affinity for 2,3- Diphosphoglycerate 2,3-DPG or 2,3-BPG is:Hg A.Hg FH BHg A2.  <response>: B i.e. HgF 2,3. DPG does not combine with fetal hemoglobin 2,3DPG Hemoglobin 2,3 DPG is present in high concentration in erythrocytes HbA HbA2 2,3 DPG greatly reduces the affinity of Hb to O2 Q shifts O2-dissociation curve to right Fetus Hb HbF consists of a2Y2, this tetramer has much lower affinity for 2-3 DPG than adult HbQ Corresponding a higher affinity for O2. 