<prompt> Which of the following is granted orphan drug status for the treatment of Dravets syndrome?StiripentolIcatibantPitolisantTafamidis  <response>: Stiripentol increases GABA transmission. It is granted orphan drug status for the treatment of Dravets syndrome Severe myoclonic epilepsy in infants.Icatibant is a bradykinin B2 receptor antagonist. It is used for acute attacks of hereditary angioedema in adults with C1-esterase inhibitor deficiency.Pitolisant aka Tiprolisant is an inverse agonist of an H3 receptor. It is under trial for schizophrenia and Parkinsons disease.Tafamidis stabilizes the correctly folded tetrameric form of TTR. It is used in familial amyloid polyneuropathy. 