<prompt> In apoptosis which isare involvedApaf-1Bcl2CaspasesProgrameed cell death  <response>: Cytochrome c is a component of the electron transpo chain in mitochondria. ... Cytochrome c is also involved in initiation of apoptosis. Upon release ofcytochrome c to the cytoplasm, the protein bindsapoptotic protease activating factor-1 Apaf-1.which is very impoant for cellular apoptosis Ref guyton and hall textbook of medical physiology 12e pg 40 