<prompt> Michaelis Gutmann bodies are seen inBrucellosisMelioidosisTularemiaMalakoplakia  <response>: Michaelis guttman bodies malacoplakia Chronic granulomatous infection as a result of the inability of macrophages to kill phagocytosed E. coli. Most commonly affects immunosuppressedBMT HIVAIDS Most commonly affects GU tract; may affect skin of perianalgenital region ulcerated abscesses and soft polypoid lesions Histology:- Dense granulomatous infiltrate comprised of von Hansemann cells large macrophages w eosinophilic cytoplasm containing Michaelis Gutmann bodies round, laminated, calcified basophilic intracytoplasmic inclusions; comprised of incompletely killed bacteria within calcified phagolysosomes; stain w von Kossa, PAS, Perls, Giemsa. Treatment:- Localized: surgical excision Nonsurgical candidates: difficult to treat; may try long courses of ciprofloxacin, TMPSMX, or clofazimine. Ref:- Review of Dermatology by Alikhan pg num:-298 