<prompt> Ectopia lends is a feature of:Marfans syndromeHomocystinuriaWeil-marchisani syndromeAll of the above  <response>: Ans. d All of the aboveCAUSES OF LENS DISLOCATIONDiseases that can be associated with subluxation or dislocation of the lens Sharp and in particular blunt injuries globe contusion Metabolic disorders- Marfan syndrome- Homocystinuria- Weil-Marchesani syndrome- Hyperlysinemia- Sulfite oxidase deficiency- Ehlers-Danloss syndrome- Osteogenesis imperfect- PEX syndrome, others Overstretching of the zonular fibers by excessive corneal and or scleral stretching- High myopia- Hydrophthalmos- Megalocornea- Staphyloma Other causesassociations- Congenital aniridia- Mandibulofacial dysplasia- Focal dermal hypoplasia- Syphilitic uveitis- Retinitis pigmentosa- Hypermature cataract- Intraocular tumors especially ciliary body melnoma IncidenceManifestationDirection of the lens subluxation luxationOther features to noteOcular traumaVery frequentAny, mainly younger age mfVariable any direction possibleTraumatic retinal detachment, traumatic secondary glaucomaPEX syndromeVery frequentOlder age mfUsually anterior or posteriorPEX glaucoma PEX iridopathy and keratopathyIdiopathic lens dislocationNot rareUsually younger age mfVariable Lens dislocation in high myopiaNot rareUsually younger age mfVariableRhegmatogenous retinal detachmentMarfan syndromeNot rareyoungerage mfUsually temporosuperior, less often naso-superiorRefer to cardiologist caution; aortic aneurysm, arachnodactylyHomocystinuriaRareyounger age mfNasal Downward, often vitreous spaceOften spherophakia,a tendency for vascular thrombosisWeil-Marchesani syndromeRareYounger age mfDownward, forwardOften small, spherical lens, small stature, brachycephaly 