<prompt> Th1 cells produce?IL-1IL-2IL-4IL-5  <response>: Ans. b IL-2Ref: Inflamm Bowel Dis. 1999 Nov;54:285-94Type 1 T helper Th1 cells produce interferon-gamma, interleukin IL-2, and tumour necrosis factor TNF- beta, which activate macrophages and are responsible for cell-mediated immunity and phagocyte-dependent protective responses. By contrast, type 2 Th Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which are responsible for strong antibody production, eosinophil activation, and inhibition of several macrophage functions, thus providing phagocyte-independent protective responses. 