<prompt> D-Dimer values may be increased in all of the following exceptMyocardial infarctionPneumoniaAnticoagulant therapyPregnancy  <response>: The d-dimer assay is not specific. Levels increase in patients with myocardial infarction, pneumonia, sepsis, cancer, and the postoperative state and those in the second or third trimester of pregnancy. Therefore, d-dimer rarely has a useful role among hospitalized patients, because levels are frequently elevated due to systemic illness.Ref: Harrisons 18e p2172, 17e p2172 