<prompt> Which one of the following compounds increases the synthesis of tumor necrosis factor, leading to activation of phagocytosis in patients with chronic granulomatous disease?AldesleukinCyclosporineInterferon-gammaInfliximab  <response>: Interferon-gamma 1b recombinant form is used in chronic granulomatous disease to decrease infection liability because it increases the formation of tumor necrosis factor TNF.Infliximab is a monoclonal antibody to TNF used in rheumatoid arthritis, and its use may lead to an increased infection rate. Aldesleukin is a recombinant form of IL-2. 