<prompt> A 45 years old female presented to the OPD with breast lump of 4 cm in left breast. On examination left axillary lymph nodes were fixed and matted. Which of the following is the preferred treatment option?Breast conservation surgery Axillary LN sampling RadiotherapySimple mastectomy Axillary LN samplingNeoadjuvant chemotherapy Modified radical mastectomy RadiotherapyHalsted radical mastectomy followed by Radiotherapy  <response>: EARLY INVASIVE BREAST Ca: stage I, IIA, IIB Rx: Breast conservation surgery BCS Axillary LN sampling ALNS Radio therapy If BCS contraindicated: simple mastectomy ALNS LOCALLY ADVANCED BREAST Ca: stage IIIA, IIIB, IIIC Rx: Neoadjuvant chemotherapy Modified radical mastectomy Radio therapy Metastatic breast Ca Rx : Hormone therapy preferred over chemotherapy 