<prompt> All are features of cushing syndrome EXCEPTViolaceous striaeHyperkalemiaThin skinHypertension  <response>: i.e. Hyperkalemia: 1111 - CMDT-11 2255-H17th Hypokalemia, hypochloremia, and metabolic alkalosis are present particularly with ectopic production of ACTH 2255-H17th Hyperglycemia, glycosuria, leukocytosis, lymphocytopenia, hypokalemia 1111 - CMDT-11Sign Symptoms of Cushing Syndrome Centripetal obesity97 Personality changes Frank psychosis Increased body weight Ecchymosis Fatigability and weakness Proximal myopathy muscle wasting Hypertension BP 15090 Edema Hirsutism Polyuria, Polydipsia Amenorrhea oligomenorrhoa Hypertrophy of clitoris Broad violaceous cutaneous striae Obesity, hypertension, osteoporosis and diabetes - are non specific and therefore are less helpful in diagnosing the conditionPENDRED SYNDROME Mutation of the Pendrin gene 7 q 31 Bilateral sensorineural hearing loss due to development abnormalities of the cochlea and goiter with occasional hypothyroidism only one and a half turns of cochlea Enlarged vestibular aqueducts Deficiency of distal coils of the cochlea Mondini deformity Autosomal recessive disorder Goitre is generally diffuse, single thyroid may be the presentation Mental retardation can occurs due to hypothyroidism Thyroid carcinoma has been observed because of the characteristically wild histology, malignancy may be incorrectly diagnosed 