<prompt> Honeycomb lung is most typical of:Centriacinar emphysemaLymphangitic spread of lung carcinomaPanacinar emphysemaHamman-Rich syndrome  <response>: Honeycomb lung refers to the gross morphology of the lung in idiopathic pulmonary fibrosis Hamman-Rich syndrome, diffuse fibrosing alveolitis, usual interstitial pneumonitis. These appearances are composed of a solid, rubbery lung with prominent interstitial fibrosis interspersed with air spaces, some cystically dilated, lined by cuboidal epithelium. Many other diseases characterized by diffuse interstitial inflammation or fibrosis may also end up with honeycomb lung. Ref: Principles and Practice of Medicine a Text book for Students and Practitioners, 1st Ed, page 310 