<prompt> In which variety of lung cancer cranial irradiation is also given in treatment?Squamous cell carcinomaSmall cell cancerNon small cell cancerAdemocarcinoma  <response>: ANSWER: B Small cell cancerREF: Harrisons 18th ed chapter 89Prophylactic Cranial Irradiation:Prophylactic cranial irradiation PCI should be considered in all patients with LD local disease - and ED extended disease-Small cell lung cancer SCLC who has responded to initial therapy. A meta-analysis including 7 trials and 987 patients with LD-SCLC who had achieved a complete remission following primary chemotherapy reported a 5.4 improvement in overall survival for patients treated with PCI. In patients with ED-SCLC who had responded to first- line chemotherapy, PCI reduced the occurrence of symptomatic brain metastases and prolonged disease-free and overall survival compared to no radiation therapy. Long-term toxicides includingdeficits in cognition have been reported following PCI and are difficult to sort out from the effects of chemotherapy or normal aging. 