<prompt> Crohns disease is best diagnosed byUpper GI seriesCT enteroclysisCapsule endoscopyCECT  <response>: Diagnosis CT Enteroclysis: IOC for diagnosis of Crohns disease Earliest radiographic findings in enteroclysis are aphthous ulceration, a coarse villous pattern of the mucosa, and thickened folds Ulcerations on the mesenteric aspect with sacculation on the antimesenteric surface. Serology : Anti-Saccharomyces cerevisiae ASCA autoantibodies have specificity of 92 for Crohns disease. 