<prompt> Which of the followign drugs require dose adjustment in renal failure?CefoperazoneDoxycyclineStreptomycinRifampicin  <response>: Ans. C StreptomycinRef: Katzung 10e p835 KDT 8e p746Streptomycin is an aminoglycoside and require dose adjustment in renal failure whereas doxycycline, rifampicin and cefoperazone are secreted in bile and do not require dose adjustment in renal failure. 