<prompt> Select the most common clinical sign or symptom for diagnosis Tuberous sclerosisA 6-month-old child with blindness on the same side as a large facial lesionAn infant with infantile spasms, a hypsarrhythmic EEG pattern, and ash-leaf depigmentation on her backAn 18-year-old patient with a history of fractures and optic gliomas, who now has developed a malignant schwannomaA 2-year-old child with multiple episodes of skin infection and failure to thrive  <response>: Tuberous sclerosis, an autosomal dominant condition, can result in severe mental retardation and seizures. Infantile spasms, a hypsarrhythmic EEG pattern, hypopigmented lesions ash-leaf spots, cardiac tumors, sebaceous adenomas, a shagreen patch a roughened, raised lesion over the sacrum, and calcifications on the CT scan are all features of this condition. No specific treatment is available. 