<prompt> Nitric oxide produces its anti-aggregatory action by increasing the levels ofcAMPcGMPADPPhosphoinositol  <response>: nitric oxide has major side effects that are mediated by activation of cytoplasmic soluble guanyl cyclase and stimulate the production of cGMP, an impoant 2nd messenger REF: ESSENTIALS OF MEDICAL PHARMACOLOGY: KD TRIPATHI:7TH EDITION;PAGE NO 103 