<prompt> True about lamotrigene -Decreased efficacy in depressionFirst choice in absence seizuret12 is 24 hrsNot metabolised in liver  <response>: Ans. is c i.e., t12 is 24 hrs o Lamotrigine is well absorbed orally, metabolized in liver. TY2 is 24 hours. o It is indicated in depressive phase of MDP. 