<prompt> Refractory Septic shock is defined as?Shock persisting 1 hour after IVF administrationShock persisting 1 hour after IVF administration and high dose vasopressorsShock that is refractory to medical treatmentShock that does not improve despite treatment for 24 hours  <response>: Septic Shock Sepsis with hypotension despite adequate fluid resuscitation for atleast 1 hr, with perfusion abnormalities. or Need of vasopressors to maintain the blood pressure Refractory Septic Shock Septic shock that last for 1 hour and does not respond to fluid or pressor administration. 