<prompt> A patient had injury to right leg by road traffic accident and his leg was amputated. This is ?DiseaseDisabilityImpairmentHandicap  <response>: Ans. is c i.e., Impairment Any loss of anatomical structure e.g. loss of leg in this question is called as impairment. According to WHO definitions, Disease: Any abnormal condition of an individual that impairs function Impairment: Any loss or abnormality of psychological, physiological or anatomical structure or function Disability: Because of impairment, any restriction or inability to perform an activity in a range considered normal for a human being Handicap: A disadvantage for a given individual, resulting from an impairmentdisability, that limitsprevents fulfillment of a role considered normal depending on age, sex, social, cultural factors for that individual For example, Event Classification Interpretation Accident Disease Impairs function of a person Loss of foot Impairment Loss of anatomical structure in the form of foot Cannot Walk Disability Walking is a normal routine daily activity of a human being Unemployed Handicap Loses out his job because he cannot walk, so cannot fulfill his role in the society, i.e, earning for his family members 