<prompt> Maternal Alpha-fetoprotein concentration in serum is elevated in all except :hepatomaHepatoblastomaEndodermal sinus tumorFetal Downs syndrome  <response>: AFP :It is increased in the circulation of patients with hepatocellular carcinoma teratocarcinoma of ovary pregnancy with fetal malformations of neural tube In nonpregnant females normal value is 15ngdl.A AFP value of 300ngdl is often associated with cancer,and nonmalignant liver diseases TEXTBOOK OF BIOCHEMISTRY,D.M.VASUDEVAN,pg no:576,6th edition and refer to previous question 