<prompt> A patient comes to the emergency depament with vomiting, diarrhea, lacrimation abdominal cramps, piloerection. The family members gave history of substance use for the past 1 month. The clinical presentation is due toopiod intoxicationopiod withdrawlcocaine intoxicationcocaine withdrawl  <response>: In opioid withdrawal ALL ORIFICES BLEED Lacrimation, vomiting, rhinorrhea, diarrhea, mydriasis, kicking the habit, muscle cramps, abdominal cramps, tachycardia, cold turkey Ref.Kaplon and Sadock, synopsis of psychiatry, 11 th edition, pg no.660 