<prompt> Anion gap is mostly due to:ProteinsSulphatesPhosphatesNitrates  <response>: A i.e. Proteins Anion gap AG -Represents unmeasured anions in plasmaQ - AG is mostly due to proteinsQ - Normal AG is 10 -12 mmolLQ. - Decrease in serum albumin by 1gdi decreases AG by 2.5meqLQ - 0 O_ alignleft height183 width53The concentration of anions and cations in plasma must be equal to maintain electrical neutrality. However, only ceain cations Nat and anions C1-, HCO3- are routinely measured in clinical laboratory. Anion gap AG represents the unmeasured anions in the plasma. difference between unmeasured cations unmeasured anions It is calculatedQ as follows: AG The most impoant unmeasured cations: Ca2, Mg2, K The most impoant unmeasured anions: Proteins Albumin, sulphate, phosphates Proteins are present in our body in much more quantities as compared to other unmeasured anions. 