<prompt> The karyotype of a patient with Androgen Insensitivity Syndrome is:46XX46XY47XXY45X0  <response>: Androgen Insensitivity Syndrome is the largest single entity that leads to 46, XY undermasculinization. AIS is divided into three categories that are differentiated by the degree of genital masculinization: Complete Androgen Insensitivity Syndrome CAIS is indicated when the external genitalia is that of a normal female, Mild Androgen Insensitivity Syndrome MAIS is indicated when the external genitalia is that of a normal male, and Paial Androgen Insensitivity Syndrome PAIS is indicated when the external genitalia is paially, but not fully masculinized. Ref:Kligman, Behrman, Jenson, Stanton 2008, Chapter 589, Disorders of Sex Development, In the book, Nelsons Textbook of Pediatrics, Volume 2, 18th Edition, New Delhi, Page 1164 