<prompt> A 30-year-old patient presented with a history of jaundice for 10 days. His liver function tests showed bilirubin of 10 mgdl, SGOTSGPT - 11001450, serum alkaline phosphatase -240 IU. He was positive for Hbs Ag. What should be the confirmatory test to established acute hepatitis B infection -IgM ant i-HBc antibodyHbe AgHBV DNV by PCRAnti-HBc antibody  <response>: AntiHBc is the earliest marker seen in blood paicularly REF:MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.546 