<prompt> In HLA system, the cluster of genes are located inChromosome 6Chromosome 21X-ChromosomeY-chromosome  <response>: Chromosome 6 133-A Major histocompatibility complexes MHC also known as the HLA system after human leucocyte antigenThis is a cluster of gene on chromosomes 6 that is responsible for immunological specificity The proteins for which they code are attached to cell surfaces and act as chaperones for foreign antigens which have to be accompanied by HLA before they are recognized and engaged by the bodys T-cells 