<prompt> A patient with bipolar disorder staed lithium therapy. The maximum therapeutic level of lithium in serum is:0.1 meqL0.4 meqL1.0 meqL1.8 meqL  <response>: Concentrations considered to be effective and acceptably safe are between 0.6 and 1.5 mEqL. The range of 1.0-1.5 mEqL is ored for treatment of acutely manic or hypomanic patients. Serum concentrations of Li have been found to follow a clear dose-effect relationship between 0.4 and 1.0 mEqL, but with a corresponding dose-dependent rise in polyuria and tremor as indices of adverse effects. Ref: Meyer J.M. 2011. Chapter 16. Pharmacotherapy of Psychosis and Mania. In B.C. Knollmann Ed, Goodman Gilmans The Pharmacological Basis of Therapeutics, 12e. 