<prompt> Increased LDH is an impoant marker for:Bulky DiseaseLymphomaLiver metastasisLung metastasis  <response>: Answer is A Bulky Disease: The most impoant role of serum LDH is to estimate the tumor bulk volume of tumor. LDH levels are elevated in large volume bulky tumors of any histology. LDH levels when elevated correlate well with the volume of tumor -- The Essential of clinical oncology. LDH elevation provides a useful guide to bulk of disease; Bulky Disease In Hodgkins Lymphoma is a node mass more than 10 cm in diameter - Essential Revision notes jiff MRCP by Katra PasTest2004288 Serum LDH is a non specific marker elevated in a variety of tumors. 