<prompt> A mother with 10 weeks pregnancy and who had previously delivered a baby with open neural tube defect which statement is trueSodium valproate causes open neural tube defectRisk of recurrence is 10Amniocentesis should be doneGive multivitamin  <response>: Ans. is a i.e Sodium valproate causes open neural tube defect Sodium valproate used during pregnancy, has produced neural tube defects in the offspring; therefore should be avoided. KDT 5e, p 375 Therefore option a is correct The risk of recurrence of anencephaly is 5 after one affected child and 13 after two affected children deg 