<prompt> Kayser-Fleisher ring is seen inWilsons diseaseStills diseaseSystemic lupus erythematosusChalcosis  <response>: Ans. a Wilsons disease. Ref. Parsons, Disease of Eye, 19th ed., 568.Useful diagnostic tests for wilson diseaseTestUseful-nessNormal valueHeterozygouscarriersWilson diseaseSerumCeruloplasmin180-350 mgLLow in 20Low in 85Kayser-Fleischer KF ringsAbsentAbsentPresent in 99. if neurologic or psychiatricPresent in 99. if neurologic or psychiatric symptoms present. Present in 30-50 in hepatic presentation and presymptomatic state.24-h urine Cu0.3-0.8 nmol 20-50 mgNormal to 1.3 pmol1.6 pmol 10mg in symptomatic patients. 0.9 to 1.6 pmol 80 mg.60 to 100 mg in presymptomatic patients, obstructive 20-50 mg tissueLiver Cu0.3-0.8 mmolgNormal to 2.0 pmol3.1 pmol 200 mgfalse-positive resultsHaplotype AnalysisSiblings only0 Matcheslmatch2 matches 