<prompt> Haemophilus influenzae has been isolated from the CSF of two year old boy suffering from meningitis. The strain is beta-lactamase producing and resistant to chloramphenicol. The most appropriate antimicrobial in such a situation is -Trimethoprim-sulphamethoxazole combinationCiprofloxacinThird-generation cephalosporinVancomycin  <response>: Ans. is c i.e., Third generation cephalosporins DOC for H. influenzae meningitis Cs -- Third generation cephalosporin. 