<prompt> VWF factor deficiency causes:Platelet adhesionFactor VIII in plasmaDefective platelet adhesionAll of the above  <response>: Deficiency of Von willebrand factor VWF -promote platelet adherence and activation causes Platelet adhesion BT Intrinsic pathway activity aPTT Factor VIII in plasma CF Mucosal bleeding - Petechiae purpura epistaxis melena Tissue bleeding Rx - Desmopressin for mild form - Cryoprecipitate for severe form 