<prompt> Both loop diuretics and thiazides can cause hypokalemia by:Inhibiting proximal tubular KreabsorptionInhibiting Na-K-2Cl-cotranspo in the ascending limb of loop of HenleIncreasing the availability of Nain the distal tubular fluid to exchange with interstitial KPotentiating the action of aldosterone  <response>: Diuretics prevent the reabsorption of Na-more amount of Na reaches the distal poion of the nephron i.e. late DT and collecting ducts. Na is exchanged with K and H Increased distal delivery of Na results in more exchange and thus hypokalemia 