<prompt> Molecular studies on an abdominal lymph node containing lymphoma demonstrate t2;8p12;q24 translocation. This is most compatible with which of the following diseases?Burkitts lymphomaMantle cell lymphomaMultiple myelomaSmall cell lymphoma  <response>: Burkitts lymphoma is actually associated with three translocations. The common variant t8;14q24;q32, involving the oncogene myc on chromosome 8, and the heavy immunoglobulin chain on chromosome 14. The other two variants are: t8;22q24;q11, involving myc and the lambda light chain immunoglobulin site, and t2;8p12;q24, involving the kappa light chain and myc. Mantle cell lymphoma, multiple myeloma, and small not cleaved cell lymphoma are associated with the t11;14q13;q32 translocation involving bcl -1 and the heavy chain site. Ref: Friedberg J.W., Perkins A.S. 2010. Chapter 104. Burkitt Lymphoma. In J.T. Prchal, K. Kaushansky, M.A. Lichtman, T.J. Kipps, U. Seligsohn Eds, Williams Hematology, 8e. 