<prompt> A 15-year-old boy needs to go for a long distance in bus. Which of the following drugs would be useful for him?DesloratiadineCetirizineDiphenhydraminePromethazine  <response>: DrugIndicationDosageHow to useAdverse effectsAnticholinergic:ScopolamineSea and travel sicknessTransdermal 1.5 mgpatchPrevention: 6-8 hours before exposure Effective for 72 hours.Dry eyes, mouth, mydriasis with light sensitivity Rare: Glaucoma, cataract, dermatitis, unilateral mydriasisAntihistamines:Cinnarizine DimenhydrinateVertigoCinnarizine 20 mgDimenhydrinate 40 mgAcute treatment only TDS for 4 weeksDrowsiness, headache, Rare: Urinary retention, paresthesia, amnesia, sweating, tinnitusDimenhydrinate Nausea and vomiting Motion sickness50-100 mg OD Cl 3 years dose reduced in childrenPrevention: 0.5-1 hours before start of travelSomnolence, drowsinessDiphenhydramineNausea, vomiting, sleep disturbances50 mgday Cl 18 yearsShort-term therapy: 30 minutes before sleepAddiction, tolerance development, drowsiness, muscle weaknessPromethazineNausea and vomiting20-30 mg starting dose Can be given in children 2 years of ageReserve drugSedation, anticholinergic side effects 