<prompt> Which of the following is a poor prognostic factor for childhood ALL.Total Leukocyte count 4000-100,000Age 2 yearsTesticular involvementBlasts in peripheral smear  <response>: Answer is C Testicular involvement Testicular involvement enlargement is a typical poor prognostic factor for childhood ALL Age 2 years versus Testicular Involvement Typically Age 1 year is considered a poor prognostic factor Although Age 2 year has been mentioned as a poor prognostic factor in ceain textbooks including Hoffmans Hematology 4th1158 most textbooks use the criteria of Age 1 year to define a poor prognostic factor Since testicular involvement provided amongst the option is an established poor prognostic factor, this is selected as the single best answer of choice. 