<prompt> CNS affection of a local anesthetic agent leads to?ConvulsionPerioral numbnessDepressionAll of the above  <response>: Ans is d i.e. All of the above Manifestations of local anesthetic toxicityA. Early symptoms ProdromeCircumoral numbness, dizziness, tongue paresthesia, restlesness, tinnitus, agitation.B. CNS symptoms These are biphasic i.e. excitation convulsions, restlessness, agitation 8c tinnitus, followed by depression drowsiness, disorientation, respiratory depression, unconciousness.C. Cardiovascular manifestationshypotension, cardiac arrest, coma 