<prompt> Atheromatous changes of blood vessels affects early in -KidneyLiverHeartSpleen  <response>: Sites of Atherosclerosis Atherosclerotic plaques develop primarily in elastic arteries e.g., aorta, carotid and iliac arteries, and large medium sized muscular arteries e.g., coronary artery and poplitial arteries.In descending order, the vessels most commonly involved are -Abdominal aorta most common Causing aneurysmCoronary arteries heart Causing MIPopliteal arteries Causing ischemic gangrene of lower limbs.Internal carotid arteries Causing strokeCircle of willis Causing strokeVessels usually spared areVessels of upper extremitiesMesentric and renal vessels, except at their 