<prompt> Immunosuppressant drug inhibiting the action of IL-2 without inhibiting its transcription is:PrednisoloneCyclosporineTacrolimusSirolimus  <response>: Cyclosporine and tacrolimus are calcineurin inhibitors. These inhibit the formation gene transcription of interleukins. Sirolimus is mTOR inhibitor. It inhibits the action of interleukins after their formation. 