<prompt> Adverse Adverse effects of phenytoin include all of the following except?LymphadenopathyAtaxiaHypercalcemiaHirsutism  <response>: Phenytoin interferes with calcium metabolism by desensitizing target tissue to vit. D, this causes hypocalcemia not hypercalcemia. At therapeutic level 10-20microgml - Gum hyperophy, hirsutism, hypersensitivity rashes, lymphadenopathy, DLE, neutropenia, hyperglycemia due to inhibition of insulin release, megaloblastic anemia, pseudolymphoma, hypocalcemia, Vitamin D deficiency and osteomalacia, and teratogenicity fetal hydantoin syndrome. At toxic level dose-related cerebellar syndrome ataxia, veigo, falling BP, arrhythmias, drowsiness, mental confusion, Gl symptoms epigastric pain, nausea, vomiting and local vascular injury by iv injection. REF : katzung pharmacology : 14th ed 