<prompt> In Neonatal cholestasis direct bilirubin is -10152025  <response>: Ans. is c i.e., 20 Neonatal cholestasiso Prolonge elevation of serum level of conjugated bilirubin beyond the 1st 14 days of life,o Causes may be:InfectiousGeneticMetabolicMechanical obstruction BiliaryIdiopathicPathological Jaundice Ghai TYep. 147STB Serum Total bilirubin 5 mg;dl DI10mgdID212-13 thereaftero Appearence of Jaundice within 24 hour,o Jaundice beyound 3 week In Nelson beyond 2 week,o Conjugated bilirubin.o Direct reacting bilirubin 2 mgdl at any time, or more than 20 of total serum bilirubin Journal America! Family Physician--Feb. 2000 