<prompt> The endotoxin of the following gram negative bacteria does not play any pa in the pathogenesis of the natural disease?E.coliKlebsiellaVibrio choleraePseudomonas  <response>: Ans. c. Vibrio cholerae Endotoxin of Vibrio cholerae plays no role in pathogenesis of cholera. Vibrio cholerae Comma shaped, isolated by Kochdeg Arranged as fish in stream appearance Possess single polar flagella and shows daing type motility swarm of gnatsdeg Cholera Vibrios also possess the Lipopolysaccharide 0 antigen LPS Endotoxin as in gram negative intestinal bacilli. This a.pparently plays no role in pathogenesis of cholera, but is responsible for immunity induced by killed vaccines. - Ananthnarayan 8e p307 