<prompt> CLL is characterised by following except -Small lymphocytes in peripheral smearHepatosplenomegalyAge 50 years and usually femalesZAP-70 is a marker  <response>: Chronic Lymphocytic leukaemia occurs more commonly in middle and older age groups over 50 years of age with a male preponderance ,male - female ratio 2:1 Reference best book of Pathology 7th edition author Harsha Mohan page number 355 