<prompt> Decrease in the normal basophilia of the nuclear chromatin in a necrotic cell is known as:PyknosisKaryolysisKaryorrhexisMyelin figures  <response>: Nuclear changes appear in necrotic cells in one of three patterns, all due to nonspecific breakdown of DNA. The basophilia of the chromatin may fade karyolysis, a change that presumably reflects loss of DNA because of enzymatic degradation by endonucleases. A second pattern is pyknosis, characterized by nuclear shrinkage and increased basophilia. Here the chromatin condenses into a solid, shrunken basophilic mass. In the third pattern, known as karyorrhexis, the pyknotic nucleus undergoes fragmentation. With the passage of time a day or two, the nucleus in the necrotic cell totally disappears.Ref: Robbins 8th edition, Chapter 1. 