<prompt> Which of the following medication is least effective against depression?ValproateLamotrigineLithiumAripiprazole  <response>: Valproate Antiseizure drug In addition, it is used as a mood stabilizer in bipolar disorder and as prophylactic treatment for migraine. Least effective against depression Treatment : Pharmcotherapy- TCAs SSRIM.C. SNRI MAO inhibitors Atypical antidepressants Psychotherapy ECT 