<prompt> A five year old boy presents with precocious pubey and a blood pressure of 13080 mmHg. Estimation of which of the following will help in diagnosis ?17 hydroxy-progesteroneCoisolAldosterone11 deoxycoisol  <response>: Ans. is d i.e. 11 deoxycoisol o At the age of 5-6 years, BP in excess of 11575 mm Hg is considered as hypeesion This boy has BP 13080. o So, the boy in this question has : ? i Precocious pubey ii Hypeension o Precocious pubey in male, with salt retention and hypeension, occurs due to deficiency of 11-13 Hydroxylase which catalyzes the conversion of 11 deoxycoisol to coisol. 