<prompt> Which one of the following ultrasound marker is associated with greatest increased risk for Trisomy 21 in fetusEchogenic foci in heartHyperechogenic bowelChoroid plexus cystsNuchal edema  <response>: D Nuchal edemaINCIDENCE OF MAJOR MINOR DEFECTSMA Trisomy 21NormalLikelihood ratio for isolated marker Nuchal Fold33.50.69.8 Short humerus33.41.54.1 Short femur41.45.21.6 Hydronephrosis17.62.61.0 Echogenic focus in heart28.24.41.1 Echogenic bowel13.30.63.0 Major defect21.40.655.2 