<prompt> Macrophage activation syndrome is characterized by all except ___HemophagocytosisHypofibrinogenemiaHyperiglycidemiaHypoferritenemia  <response>: Macrophage activation syndrome is characterised by all if the listed feature except Hypoferritenemia . Macrophage activation syndromeMAS is rare but potentially fatal complication of systemic JIA. It is characterized by the following: Macrophage hemophagocytosis in the bone marrow Hypofibrinogenemia paradoxical fall in erythrocyte sedimentation rate ESR Hyperiglyceridemia Extreme hyperferritinemia Fever 38.5oC Splenomegaly Cytopenia affecting atleast two or three cell lineages. Reference : nelson textbook of pediatrics 21st edition Pgno: 1262 