<prompt> Which of the following antitubercular drugs are associated with hypothyroidism?EthionamideStreptomycinPZARifampicin  <response>: Ethionamide is thought to prevent organification of iodine in thyroid hormone synthesis, as it is structurally related to other thionamides propylthiouracil and methimazole. So, it can lead to hypothyroidism. 