<prompt> In-situ DNA nick end labeling can quantitateFraction of cells in apoptotic pathwaysFraction of cells in S phasep53 gene productbcrabl gene  <response>: In situ DNA nick end labeling is an in-situ method for detecting areas of DNA which are nicked during apoptosis.Terminal deoxynucleotidyl transferase mediated dUTPbiotin nick end labeling TUNEL is a method for detecting apoptotic cells that exhibit DNA fragmentation. 