<prompt> A child presented with edema, massive proteinuria and hyperlipidemia. True statement about this condition is:Type of focal segmental GNIgA deposition on basement membraneFoot process of glomerular membrane normalGlomerular function is lost due to loss of polyanionic charge on both sites of glomerular foot process  <response>: Glomerular barrier function depends on the molecular size the larger, the less permeable and charge the more cationic, the more permeable is done. The anionic moieties present within the capillary wall including the acidic proteoglycans of the GBM and the sialoglycoproteins of epithelial and endothelial cells are responsible for the viually complete exclusion of albumin also having anionic charge from the filtrate. 