<prompt> All of the following drugs can precipitate tacrolimus toxicity except -GentamycinCisplatinVancomycinRifampicin  <response>: Ans. is d i.e., Rifampicin Tacrolimus is a highly nephrotoxic drugs. o Other nephrotoxic drugs may precipitate tacrolimus induced nephrotoxicity, when used concomitantly. o Impoant nephrotoxic drugs that enhance tacrolimus induced nephrotoxicity are: 1. Aminoglycosides e.g. gentamycin 2. Vancomycin 3. Cisplatin 4. Amphotericin B 5. Cotrimoxazole 6. NSAIDs 