<prompt> Direct action on Nm Cholinoreceptors is shown by-PhysostigmineNeostigmineBoth the aboveNone of the above  <response>: Ans. is b i.e.b Neostigmine Comparative features of physosdgmine and neostigmine PhysostigmineNeostigmine1. SourceNatural alkaloid form Physosiigma venenosum Calabar beanSynthetic2. ChemistryTertiaryr amine derivativeQuaternary ammonium compound3. Oral absorptionGoodPoor4. CNS actionsPresentAbsent5. Applied to eyePenetrates corneaPoor penetration6. Direct action on Xm cholinoceptorsAbsentPresent7. Prominent effect onAutonomic effectorsSkeletal muscles Important useMiotic glaucomaMyasthenia gravis9. Dose0-5-1 mg oralparenteral0-I-T0eye drops0-5-2-5mgi.m.s.c.15-30 mg orally10. Duration of actionSystemic 4-6 hrsIn eye 6 to 24 hrs3-4 hrs. 