<prompt> In normal kidneys, which of the following is true of the osmolarity of renal tubular fluid that flows through the early distal tubule in the region of the macula densa?2018Usually isotonic compared with plasmaUsually hypeonic compared with plasmahypeonic compared with plasma in antidiuresisUsually hypotonic compared with plasma  <response>: distal tubule, paicularly its first pa, is in an extension of the thick segment of the ascending limb. It is relatively impermeable to water, and continued removal of the solute in excess of solvent fuher dilutes the tubular fluidhypotonic fluid. Ref:- Ganong, pg num:-684 