<prompt> Which of the following statements about oral anticoagulants is FALSE?They interfere with an early step in the synthesis of clotting factorsIrrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 daysTheir dose is adjusted by repeated measurement of prothrombin timeThey are contraindicated during pregnancy  <response>: Ref: KDT 6e p600, 601 Oral anticoagulants inhibit the activation of factor II, VII, IX and X. these do not affect the synthesis of these factors. 