<prompt> True about thiopentone-Long actingGood analgesic actionCerebroprotectiveGood muscle relaxation  <response>: Barbiturate-induced reductions in oxygen requirements and cerebral metabolic activity are mirrored by changes in the electroencephalogram EEG, which progress from low-voltage fast activity with small doses to high-voltage slow activity, burst suppression, and electrical silence with larger doses. Barbiturates may protect the brain from transient episodes of focal ischemia eg, cerebral embolism but probably do not protect from global ischemia eg, cardiac arrest. With the reduction in CMRO2, a parallel reduction in cerebral perfusion occurs, as seen in decreased cerebral blood flow CBF and ICP. Ref: Millers anesthesia 8th edition Ref: Morgan Mikhails clinical anesthesiology 6e. 