<prompt> Miotic agent used in glaucoma:MethacholinePilocarpineCevimelineBethanechol  <response>: Ref: KDT 8th ed. pg. 167Pilocarpine is a directly acting parasympathomimetic cholinergic drug which acts mainly on pupil M3 causes miosis.Reduces IOP within few minutes and lasts for upto 4-8 hrsHence used in Glaucoma OAG patients.Methacholine is a directly acting parasympathomimetic cholinergic drug which acts mainly on myocardium M2 causing bradycardia. Hence used to treat tachycardia and can also be used to diagnose bronchial hyperactivity methacholine challenge test. Half-life: 2 hoursBethanechol is directly acting parasympathomimetic cholinergic drug which works on bladder M3 and is used in acute urinary retentionAtonic bladder. Half-life: 2 hoursCevimeline is recently approved drug used for xerostomia in sjogren syndrome or for patients undergoing chemotherapy. 