<prompt> The major risk factor for bipolar disorder isPositive family history of bipolarHigh neuroticism in personalityLow socioeconomic statusStressful life events  <response>: There are several factors that is said to be a causation for bipolar disorders they can be classified under nature versus nuure hypothesis natural causes plays a impoant role and one of the impoant cause among them is family history or high genetic loadine more the number of genes more is the risk of bipolar disorder in a person Reference: Kaplon and sadock, 11 th edition, synopsis of psychiatry, 11 th edition, pg no. 355 