<prompt> Atypical antipsychotic with least extrapyramidal side effectsClozapineRisperidoneOlanzapineZiprasdone  <response>: A Clozapine Clozapine: The risks of extrapyramidal side effects such as Tardive dyskinesia are much less when compared with typical antipsychotics may be due to Clozapines anticholinergic effects. Extrapyramidal symptoms subside somewhat after a person switches from another antipsychotic to Clozapine. 