<prompt> The most effective method of reduction of incidence of institutional pediatric staphylococcus aureus infection is ___Mask and gloves use with each suspected patientMeticulous handwashing before and with patientsTreatment of all culture Positive patients with vancomycinRoutine isolation of culture Positive  <response>: S.aureus is transmitted primarily by direct contact. Strict attention to handwashing techniques is the most effective measure for preventing the spread of staphylococci from one individual to another. Use of a hand wash containing chlorhexidine or alcohol is recommended. Reference: Nelson textbook of pediatrics 19th edition Page 908 