<prompt> Condition caused by deficiency of fibrillin 1 is?Marfan syndromeEhler Danlos syndromeOsteogenesis imperfectaAngelman syndrome  <response>: Ans. is a i.e., Marfan syndrome Marfan syndrome is an autosomal dominant disorder due to mutation in fibrillin-1 gene on chromosomal 15.About other options EDS comprises a clinically and genetically heterogenous group of disorders that result from some defect in the synthesis or structure of collegen and characterized by hyperelasticity of skin and hypermobile joints Osteogenesis imperfecta, also called brittle bone disease or Lobstein syndrome, is an autosomal dominant disorder due to defect in type-1 collagen Duchenne Muscular Dystrophy DMD is an X-linked recessive disorder. It is caused by a mutation in gene responsible for producing dystrophin a sarcolemmal protein. 