<prompt> Angioid streaks are seen in ?Pseudoxanthoma elasticumPagets diseaseOld ageAll of the above  <response>: Ans. is d i.e., All of the above Angioid streak Angioid streaks are dark brown pigmented streaks that radiate from the peripapillary retina into the macular and peripheral fundus. The streaks represent linear crack like dehiscences in Bruchs membrane. These are due to changes in the elastic tissue of Bruchs membrane and are frequently associated with more widespread degeneration of similar nature as in the elastic tissue of skin pseudoxanthoma elasticum or aerial walls. Nearly 50 of patients with angioid streaks have an associated systemic disease. Most common association of Angioid streaks is with age related degeneration of Bruchs membrane. Other diseases associated are Pseudoxanthoma elasticum, Pagets disease of bone, Ehlers Danlos syndrome, several hemoglohinopathies such as sickle cell disease. 