<prompt> L.E. Cell phenomenon in peripheral blood is seen in:Rheumatic heart diseaseInfective endocarditisIschemic heart diseaseSystemic Lupus Erythernatosus  <response>: The addition of blood serum from a person under suspicion to the buffy coat of normal blood is the basis for L.E .cell phenomenon. If the patient is L.E. -we, then typical LE Cell develop. The cell consists of rosette of neutrophils surrounding a pale nuclear mass, derived from a Lymphocyte. 