<prompt> The FMR1 proteinIs expressed in fragile X-associated mental retardationIs normally found in brain and ovariesWhen defective, is not sufficient to cause the fragile X-associated mental retardation syndromeIs coded by the FMR1 gene which has the 5-CGG-3 n repeat segments  <response>: The family mental retardation FMR1 protein is normally expressed in brain and testes. It is encoded by the FMR1 gene. Amplification of the CGG region to a repeat number greater than 200 causes methylation of the CpG is land and prevents the FMR1 protein from being expressed. This defect is sufficient to cause the fragile X-associated mental retardation syndrome. 