<prompt> Which cereal is not to be given in celiac sprue?WheatMaizeCornRice  <response>: Ans. a WheatRef.: Harrison 19th ed. 1940 Coeliac disease is caused by a reaction to gliadin found in wheat, oats, rye and Barley. Upon exposure to gliadin, there is production of anti-tissue transglutaminase antibody which cross-reacts with small-bowel tissue, causing an inflammatory reaction. This leads to villous atrophy and leads to osmotic diarrhea. 