<prompt> Nicotine deaddiction uses all exceptNicotine PatchNicotine SprayNicotine InhalerNicotine subcutaneous Injection  <response>: D Nicotine subcutaneous Injection CLINICAL PRACTICE GUIDELINES Physician actions: Ask: Systematically identify all tobacco users at every visit Advise: Strongly urge all smokers to quit Identify smokers willing to quit Assist the patient in quitting Arrange follow-up contact Pharmacologic interventions -- First-line therapies: Nicotine gum 1.5 Nicotine 24-h patch: 21-mg patch for 4 weeks, 14-mg patch for 2 weeks 7-mg patch for 2 weeks 1.9 Nicotine nasal inhaler: one spray to each nostril 1-2 timesh for 3-6 months 2.7 Nicotine oral inhaler: 6-16 puffs per day for up to 6 months 2.5 Bupropion: 150 mgd PO for 3 days followed by 150 mg bid for 7-12 weeks 2.1 Pharmacologic interventions -- Second-line therapies: Clonidine: Initial dose 0.1 mg bid PO, or 0.1-mg transdermal patch, increasing to 0.15-0.75 mgd PO or 0.2-mg patch for 3-10 weeks 2.1 Nortriptyline: Initial dose 25 mgd PO, increasing to 75-100 mgd for 12 weeks 3.2 Other interventions: Physician or other medical personnel counseling, 10 minutes Intensive smoking cessation program Clinic-based smoking status identification system Counseling by nonclinicians and social support by family and friends Telephone counseling 