<prompt> Wermer syndrome isMEN1MEN IIAMEN IIBAIP  <response>: Wermer syndrome is otherwise known as Multiple Endocrine neoplasia type 1 MEN 1. It is characterised by primary hyperparathyroidism,endocrine tumours of pancreas, and abnormalities of pituitary primarily prolactinoma. It is due to germline mutation of MEN1 tumour suppressor gene,which encodes a protein called menin. Ref :ROBBINS text book of pathology 