<prompt> Platelet aggregation is caused by -Nitrous oxideThromboxone A2AspirinPGI2  <response>: Robbins basic pathology 9th edition page no 46, Answer is option 2, thromboxaneA2 Thromboxane A2 is a potent platelet aggregating agent and a vasoconstrictor, is the major prostaglandin produced in these cells. Itvis an intrmediate produced in the cyclooxygenase pathway by the enzyme thromboxane synthase. 