<prompt> Anti-coagulant of choice for heparin induced thrombo.. Cytopenia is?LepirudinAprotininAbciximabPlasminogen  <response>: Lepirudin is a parenterally acting direct thrombin inhibitor. They inactivate fibrin bound thrombin in their clots since their activity is independent of antithrombin III. It;s use has been approved in HIT. From medical pharmacology padmaja 4th edition Page no 338 