<prompt> THEME AND FOCUS: GLYCOLYSIS Case Study: A 42-year-old man presented with symptoms of weakness, fatigue, shoness of breath, and dizziness. His hemoglobin level was less than 7 gdl normal for a male being greater than 13.5 gdl. Red blood cells of the patient showed abnormally low level of lactate production. Heinz bodies were not found in PBF. Lead Question: Deficiency of which one of the following enzymes would be the most likely cause of this patients anemia?Phosphoglucose isomeraseG6PDPyruvate kinaseHexokinase  <response>: Pyruvate kinase deficiency would be most likely cause of patients anemia lactate production in the erythrocyte indicates a defect in glycolysis. Pyruvate kinase deficiency 2nd most common cause after glucose 6-phosphate dehydrogenase deficiency of enzyme deficiency related to hemolytic anemia. In G6PD deficiency - Heinz bodies 