<prompt> Pantothenate Kinase associated neurodegeneration is:Wiisons diseaseHallervorden-Spatz syndromeMcLeod syndromeLesch Nyhan syndrome  <response>: Ans. B. Hallervorden-Spatz syndromePantothenate kinase associated neuro degeneration PKAN formerly Hallervorden-Spatz syndromeRare autosomal recessive neuro degenerative disorderChorea, dystonia, parkinsonian features, pyramidal tract features and MRMRI-decreased T2 signal in the globus pallidus and substantianigra, eye of the tiger sign hyperintense area within the hypointense areaSometimes acanthocytosisNeuropathologic examination indicates excessive accumulation of iron-containing pigments in the globuspallidus and substantianigra.Similar disorders are grouped as neurodegeneration with brain iron accumulation NBIA. 