<prompt> Most specific antiemetic for chemotherapy induced vomiting is:GranisetronTegaserodDomperidoneDoxylamine  <response>: Ans. A GranisetronRef: Harrison 20the p501Drugs for chemotherapy induced vomiting5 HT3 blockers like ondansetron, granisetron, dolasetron, palonosetron and ramosetron are DOC for this condition.Palonosetron is most potent 5 HT3 blocker. Dolasetron may prolong QT interval.Palonosetron has longest t12 whereas ondansetron has shortest t12.Efficacy of these drugs increases if used along with antihistaminics, D2 blockers or dexamethasone. 