<prompt> Type 1 Dentinogenesis imperfecta is caused by mutation in:DMP-1 geneBSP- 1 geneDSPP geneSPP1 gene  <response>: Type 1 Dentinogenesis imperfecta is caused by a mutation in the DSPP gene gene map locus 4q21.3, encoding dentin phosphoprotein and dentin sialoprotein. While Type 2 is caused by DMP-1, BSP-1, SPP1 gene.Ref: Shafers textbook of oral pathology 7th edition page55 