<prompt> Which of the following enzyme is responsible for respiratory burst in neutrophils?NADPH oxidaseDehydrogenasePeroxidaseCatalase  <response>: When stimulated by contact with bacteria, neutrophils exhibit a respiratory burst and produce superoxide in a reaction catalyzed by NADPH oxidase. Also know: Superoxide , hydrogen peroxide H2O2, peroxyl radicals ROO, and hydroxyl radicals OH and are referred to as reactive oxygen species ROS. Superoxide is formed in the red blood cell by the autoxidation of hemoglobin to methemoglobin; in other tissues, it is formed by the action of enzymes such as cytochrome P450 reductase and xanthine oxidase. Superoxide can release iron ions from ferritin. Ref: Murray R.K. 2011. Chapter 52. Red White Blood Cells. In D.A. Bender, K.M. Botham, P.A. Weil, P.J. Kennelly, R.K. Murray, V.W. Rodwell Eds, Harpers Illustrated Biochemistry, 29e. 