<prompt> An 18 yr old male presents with massive hematemesis; he has history of fever for the past 14 days for which he was managed with drugs; moderate splenomegaly is present; diagnosis is:NSAID induced duodenal ulcerDrug induced gastritisEsophageal varicesNone of the above.  <response>: Answer is C Esophageal varices Presence of massive haematemesis in the background of moderate splenomegaly suggests a diagnosis of esophageal varices secondary to poal hypeension. Esophageal varices : Most common presentation of esophageal varices is Hematemesis. Splenomegaly, sometimes with hipersplenism, is the next most common presenting feature in the poal vein obstruction. 