<prompt> In which of the following conditions, Aniridia and Hemihyperophy are most likely present ?NeuroblastomaWilms tumourNon-Hodgkins lymphomaGerm cell tumour  <response>: Ans. is b i.e.,Wilms tumour Wilms tumour is associated with three groups of congenital malformations. o The risk of Wilms tumour is increased in these conditions. o These are ? WAGR syndrome - It consists of o Aniridia o Mental retardation o Genital anomalies The risk of Wilms tumour is increased by 33 in this syndrome. Denys - Drash syndrome - It consists of o Gonadal dysgenesis male pseudohermaphroditism o Nephropathy leading to renal failure. Majority of patients with this syndrome have ranal failure. Beckwith - Wiedeman syndrome - It consists of o Enlargement of body organs o Renal medullary cysts. o Hemihyperophy o Abnormal large cells in adrenal coex. 