<prompt> Leucopenia in SLE is almost alwaysLymphopeniaNeutropeniaEosinopeniaAny of the above  <response>: Ans. a Lymphopenia Ref. H-17th2077; Table 313-3LeukopeniasCell typeCell countCausesNeutropeniaAbsolute neutrophil count 150 cellsmm3Sepsispostinfection, drugs including chemotherapy, aplastic anemia, SLE, radiationLymphopeniaAbsolute lymphocyte count 1500 cellsmm3 3000 cellsmm3 in childrenHIV, DIGeorge syndrome, SCID, SLE, corticosteroid, radiation, sepsis, postopEosinopenia Cushing syndrome, corticosteroidsFeatures of SLE If 4 of these criteria, well documented, are present at any time in a patients history, the diagnosis is likely to be SLE. Specificity is 95; sensitivity is 75.Malar rashFixed erythema, flat or raised, over the malar eminencesDiscoid rashErythematous circular raised patches with adherent keratotic scaling and follicular plugging; atrophic scarring may occurPhotosensitivityExposure to ultraviolet light causes rashOral ulcersIncludes oral and nasopharyngeal ulcersArthritisNonerosive arthritis of two or more peripheral joints, with tenderness, swelling, or effusionSerositisPleuritis or pericarditis documented by ECG or rub or evidence of effusionRenal disorderProteinuria 0.5 gd or 3, or cellular castsNeurologic disorderSeizures or psychosis without other causesHematologic disorderHemolytic anemia or leukopenia 4000L or lymphopenia 1500L or thrombocytopenia 100,000L in the absence of offending drugsImmunologic disorderAnti-dsDNA, anti-Sm, andor anti-phospholipidAntinuclear antibodiesAn abnormal titer of ANA by immunofluorescence or an equivalent assay at any point in time in the absence of drugs known to induce ANAs. 