<prompt> A 37 year old male patient was diagnosed with sarcoidosis of lung and was kept on glucocoicoid therapy. The treatment may result in the bone loss because glucocoicoids causes which of the following?Increases calcium absorption from the gastrointestinal tractIncreased osteoblast growthInhibit bone formationInhibit bone resorption  <response>: Glucocoicoids increase bone resorption. They have multiple actions that alter bone metabolism.Glucocoicoids decrease intestinal Ca absorption and renal Careabsorption. Both mechanisms serve to lower serum . As serum drops, secretion of parathyroid hormone PTH increases, which mobilizes Cafrom bone by stimulating resorption of bone. Glucocoicoids also directly inhibit osteoblast bone-forming functions.Reference: Berne Levy Medical Physiology; 6th edition; Page no: 749 