<prompt> Inhibition of 5-lipoxygenase is useful inCardiac failureBronchial asthmaHepatic failureAhritis  <response>: Refer KDT 6 e p223 Leukotriene are potent bronchoconstricting agents, These agents play a major role in the pathogenesis of bronchial asthma The drugs acting by inhibiting their synthesis are useful in the prophylaxis of bronchial asthma 