<prompt> Most important prognostic factor of cancer esophagus:Length of growthDepth of involvementHistology gradingImmunohistochemistry  <response>: Ans. b Depth of invasionRef: Bailey and Love 27th Edition, Page 1085 Prognostic factors of cancer esophagus: Depth of invasion Lymph node status Presence of distant metastasis Resection margin Serosal or Peritoneal involvement Vascular invasion 