<prompt> All are true regarding cryptococcal infection except -Occurs in immune-deficient statesCapsular Ag in CSF is a rapid method of detectionAnticapsular Abs is protectiveUrease test ve  <response>: 1. Capsular antigen detection from CSF or serum by latex agglutination test is a rapid and sensitive 95. 2. Cryptococcus gives Urease test positive. 3. Anticapsular Abs is not protective 4. Predisposing factors: Patients with advanced HIV infection with CD4 T-cell counts 200ml is the most impoant risk factor for C.neoformans. However, C.gattii is not associated with HIV. It usually causes infection in immunocompetent individuals. Patients with hematologic malignancies. Transplant recipients Patients on immunosuppressive or steroid therapy. 