<prompt> All of the statements are true about FLUORO QUINOLONES, except -Suspected of having teratogenic potentialAhropathy of limb-in children may occurIncrease theophylline toxicityIncrease neuromuscular blocking action  <response>: Ans. is d i.e., Increased Neuromuscular blocking action Fluoroquinolones are contraindicated in children 18 years of age, because of evidence in animals of cailage damage in developing joints. o They are contraindicated in pregnancy because of concerm for the developing fetus teratogenicity o Fluoroquinolones are enzyme inhibitors and thus inhibit the metabolism of many drugs. Plasma concentration of theophylline is increased because of inhibition of its metabolism and this results in theo phylline toxicity. Fluoroquinolenes have no N-M blocking propeies. Antibiotics with N.M blocking propey are o Aminoglycosides o Polypeptide antibiotics o Lincomycin o Tetracyclines o Clindamycin 