<prompt> Most common cause of Budd-Chiari syndrome is:Hepatic vein valvesHypercoagulable state in Nephrotic syndromePNHPolycythemia vera  <response>: Primary Budd-Chiari syndrome 75: thrombosis of the hepatic vein Secondary Budd-Chiari syndrome 25: compression of the hepatic vein by an outside structure e.g. a tumor The cause for the disease cannot be found in about half of the patients. Hepatic vein thrombosis is associated with the following in decreasing order of frequency: Polycythemia vera: is a primary,absolute erythrocytosis. The EPO levels are suppressed causing alow to normal EPO in the blood. Pregnancy Post paum state Use of oral contraceptives Paroxysmal nocturnal hemoglobinuria Hepatocellular carcinoma Lupus anticoagulant 