<prompt> A cardiologist waewnts to study the effect of an atrovastatin drug. He notes down the initial cholesterol levels of 50 patients and then administers the drug on them. After a months treatment, he measures the cholesterol level again. Which of the following is the most appropriate to test the statistical significance of the change in blood cholesterol?Paired t-testUnpaired or independent t-testAnalysis of varianceChi-square test  <response>: In the given question, a cardiologist wants to study the effect of an atrovastatin drug; he notes down the initial cholesterol levels of 50 patients and then administers the drug on them and after a months treatment, he measures the cholesterol level againSince mean cholesterol levels are being measured in the same group of individuals before and after an intervention, this is PAIRED DATAThus, the most appropriate to test the statistical significance of the change in blood cholesterol will be Students paired t-test. 