<prompt> A patient with glaucoma is being treated with systemic beta blocker. All of the following can be given to the patient except?BrimonidineDorzolamideLevobunololProstaglandin  <response>: Ans. c. Levobunolol Ref: KDT 7e p154, 6e p144: 5e p85Brimonidine, dorzolamide and prostaglandin are topical anti-glaucoma drugs. These drugs do not have systemic side effects, while levobunolol beta-blocker is systemic anti-glaucoma drug given orally, having systemic side effects. That is why in patients with glaucoma treated with systemic beta blockers, levobunolol may add on the side effects of beta-blockers, hence, avoided in the above mentioned patient.Topical Anti-glaucoma DrugsAdrenergic agonistNon-selective: Epinephrine, DipivefrineAlpha2-selective: Apraclonidine, BrimonidineAdrenergic antagonistBeta-blocker Non-selective: Timolol, Levobunolol, Carteolol, Metipranolol, AdapralolBeta 1-blocker: BetaxololMiotics direct parasympatomimeticsPilocarpine, PhysostigmineEcothiophate. Carbachol, DemacariumProstaglandin analoguesLatanoprostCarbonic anhydrase inhibitorsDorzolamideSystemic Antiglaucoma DrugsCarbonic anhydrase inhibitorsHyperosmotic agents Acetazolamide Dichlorphenamide Methazolamide Mannitol Glycerol 