<prompt> Half life of alteplase is ?5mins30mins1 hour2 hour  <response>: Ans. is a i.e., 5 mins o Alteplase has a very short half-life about 5 minutes and, therefore, is administered as a total dose equal to 0.9mg kg.o Ten percent of the total dose injected intravenously as a bolus and the remaining drug is administered over 60 minutes. 