<prompt> Paralysis of 3rd, 4th, 6th nerves with involvement of ophthalmic division of 5th nerve, localizes the lesion to -Cavernous sinusApex of orbitBrainstemBase of skull  <response>: Paralysis of 3rd, 4th, 6th nerve and involvement of ophthalmic division of 5th nerve cavernous sinus thrombosis.Paralysis of 3rd, 4h, 6th nerve, ophthalmic division of 5th nerve plus optic nerve signs orbital apex syndrome. 