<prompt> Among the following all are hydrophilic hormones that act on cytosolic receptors except one which is a lipophilic hormone that acts on nuclear receptor:ThyroxineEpinephrineGHAUTH  <response>: Ans. a. Thyroxine Thyroxine is a lipophilic hormone that acts on nuclear receptor:Classification of Hormones by Mechanism of ActionBind to Intracellular ReceptorBind to ceil surface receptor Second messengerCytoplasmic Receptors:c-AMPc-GMPCa2Phosphatidyl inositolKinase Phosphatase Glucocorticoids Mineralocorticoids0 Androgens, estrogen and progestins0 Retinoic acid retinoids Vitamin Ds 11 25-OH2 D3Nuclear Receptors: Thyroid hormones0 Retinoic acid Calcitonin Glucagon LH and FSH Norepinephrine HCG ADH CRH PTH TSH ANF NO0 a1 adrenergic Angiotensin II Oxytocin GnRH Substance P Gastrin Choiecystokinin Muscarinic Acetylcholine Vasopressin3 TRH Insulin GH EGF, FGF IGF I and II Nerve growth factor NGF PDGF Erythropoietin Prolactin0 Adiponectin and leptin 