<prompt> Which drug is essential in Sheehans syndrome:EstrogenCoisoneThyroxinGrowth hormone  <response>: Answer is B Coisone: Multiple hormones must be replaced in patients with pan-hypopituitarism, but coisol replacement is most impoant2 - Harrison 14th 1994 Sheehans syndrome is post-paum infarction of the pituitary, leading to hypopituitarism. Treatment consists of hormone replacement therapy including Glucocoicoids, Thyroid hormone, Sex steroids, Growth hormone, Vasopressin, etc. Thus, multiple hormones must be replaced, but remember that Coisol replacement is most impoant. 