<prompt> Which of the following sites is responsible for the amnestic defect in Wernickes Korsakoff - syndrome -Mamillary bodyThalamusSubthalmic nucleusMedical fore brain bundle  <response>: Ans. is b i.e., Thalamus The amnestic defects in Korsakoffs wernickes syndrome is related to lesion in the dorsomedial nuclei of thalamus.Lesions in the dorsomedial nucleus of the thalamus seems to be the best correlate of the memory disturbance and confabulation. 