<prompt> Chemical use in vaginal sponge is -Ethynil estradiolProgesteroneMifepristoneNonoxynol-9  <response>: Ans. is d i.e., Non - oxynol - 9 Vaginal sponge It is marketed in USA under the trade name TODAY. o It is small polyurethane foam sponge saturated with spermicide, nanoxynol-9. o The failure rate :- i Parous women -- 20 to 40 per 100 women years. ii Nulliparous women -- 9 to 20 per 100 women years. 