<prompt> Itai - Itai disease is caused by:Mecury toxicityCadmium toxicityLead toxicityArsenic toxicity  <response>: Cadmium poisoning causes itai-itaidisease which is also known as ouch ouch disease due to cadmium contaminated water. Cadmium poisoning also causes other signs and symptoms like yellowing of teethCadmium ring formation and chronic renal failure. 