<prompt> Resistance to acyclovir is most commonly due to mutation in a viral gene that encodes a protein that:Conves viral RNA into DNAPhosphorylates acyclovirtranspos acyclovir into the cellTranspos acyclovir out of the cell  <response>: Ref: KDT 6e p768 Nucleosidetide analogues like acyclovir act by conveing to NTPs. First phosphorylation step occurs inside the virs and resistance occurs if there is mutation in this gene. 