<prompt> A female suffering from psychosis, taking phenothiazines now complains of sudden onset of high grade fever, muscle rigidity and altered sensorium. The diagnosis is :Malignant hyperthermiaNeuroleptic malignant syndromeTardive dyskinesiaAkathesia  <response>: Ans. is b Neuroleptic malignant syndrome History of intake of antipsychotic drugs and high grade fever, muscle rigidity, altered sensorium suggests Neurolept Malignant Syndrome.Neurolept Malignant SyndromeUsually occurs in patients who are extremely sensitive to extrapyramidal effects of antipsychotics.CF:Marked muscle rigidity High feverIncrease CPKAutonomic instabilitySevere extrapyramidal syndromesTreatmentVigorous treatment with antiparkinson drugsDiazepamDantrolineBromocriptine 