<prompt> Bile ductopenia seen inGVHDAlcoholic hepatitisAutoimmune hepatitisCirrhosis  <response>: Ductopenia Ductopenia refers to a reduction in the number of ducts in an organ. It is the histological hallmark of vanishing bile duct syndrome typically 0.5 bile ducts per poal triad. The most common cause of ductopenia is primary biliary cholangitis. Other causes failing liver transplant Hodgkins lymphoma graft-versus-host disease GVHD sarcoid cytomegalovirus infection, HIV medication toxicity. Ref: Harrisons 19th edition Pgno :2027-2028 