<prompt> Extended activity of ii-lactamases inactivate ?Cephalosporins-III generationMacrolidesQuinoloneAminoglycosides  <response>: Ans. is a i.e., Cephalosporins-III generation ESBL are lactamases that mediate resistance by hydrolyzing to extended spectrum third generation cephalosporins, penicillins and monobactams e.g. aztreonam. 