<prompt> Desmopressin is preferred over vasopressin because desmopressin has all the properties except -More potentMore selective for VI receptorHas little vasconstrictor activityLonger acting  <response>: Ans. is b i.e., More selective for VI receptorVasopressin Vs. Desmopressino Major indication of ADH vasopressin is central DI.o But use of vasopressin is limited because :It has short half lifeAction is nonspecific, i.e. act on both VI and V2 receptors VI mediated vasconstriction can cause hypertensiono These shortcomings can be overcome by desmopressini Desmopressin is longer actingii Desmopressin is V2 selective - So VI mediated vasoconstriction.Desmopressin is 12 times more potent than vasopressin. 