<prompt> Local anesthetic acts by:Blocking sodium gated channelBlocking calcium gated channelBlocking potassium gated channelBlocking chloride gated channel  <response>: NORMAL LOCAL ANESTHETIC Sodium passess through voltage gated sodium channel and cause change in membrane potential and cause depolarization. Local anesthetic attatches to sodium channel and prevents propogation depolarization. LA also has mild action on potassium calcium and NMDA channels 