<prompt> HIV patient presented with diarrhea. On stool examination, following acid fast organisms was seen. What is the drug of choice in this patient?TMP-SMXNitazoxanidePrimaquineNiclosamide  <response>: MCC of diarrhea in HIV: Cryptosporidium Parvum Diagnosis: Isospora Belli Isosporiasis: Isosporiasis is effectively treated in immunocompetent and immunosuppressed persons with TMP-SMZ 160 mg800 mg orally two to four times daily for 10 days, with the higher dosage for patients with AIDS. An alternative therapy is pyrimethamine 75 mg orally in four divided doses with folinic acid 10-25 mgday orally. Maintenance therapy with low-dose TMP-SMZ 160 mg800 mg daily or three times per week or Fansidar 1 tablet weekly prevents relapse in those with persistent immunosuppression. 