<prompt> Anion-gap Metabolism with decreased vision occurs with the following poisoningCadmiumMercuryEthanolMethanol  <response>: D Methanol Acute intoxication with Methanol is common in chronic alcoholics. Headache, vertigo, vomiting, abdominal pain, dyspnea, blurred vision, and hyperemia of the optic disc can occur. Visual disturbances are caused by damage to retinal cells and the optic nerve by methanol metabolites. Severe cases of intoxication can lead to blindness. Other symptoms include bradycardia, prolonged coma, seizures, acidosis, and death by respiratory depression. Because methanol is biotransformed by alcohol and aldehyde dehydrogenase to highly toxic products formaldehyde formic acid, respectively, Ethanol, which has a high affinity for the enzyme, is useful in therapy because it reduces the biotransformation of methanol. Other treatments include hemodialysisto enhance removal of methanol its products and alkalinization to reverse metabolic acidosis 4-methylprazole, an inhibitor of alcohol dehydrogenase, has also been proposed for treatment. Treatment with ascorbic acid would aggravate the acidosis. 