<prompt> 1730. A nine month old boy of Sindhl parents presented to you with complaints of progressive lethargy, Irritability pallor since 6 months of age. Examination revealed severe pallor. Investigation showed Hb-3.8 mg; MCV-58fl; MCH-19.4 pg cell. Blood film shows osmotic fragility Is normal target cells and normoblasts. X-ray skull shows expansion of erythroid marrow. Which of the following Is the most likely diagnosisIron deficiency anemiaAcute lymphoblastic anemiaHemoglobin D diseaseHereditary spherocytosis  <response>: In iron deficiency anemia ,hemoglobin will be mild to moderate but occasionally it may be markedless than 6gdL. In peripheral smear,microcytic hypochromic red cells are seen;target cells ,polychromatic cells, normoblasts are seen.MCV will be less than 80fl MCH less than 27pg. The marrow hypercellularity is increased due to marrow hyperplasia .Reference :Harsh mohan textbook of pathology sixth edition pg no 299 