<prompt> Increased levels of which of the following in amniotic fluid is an indicator of neural tube defect in the fetus :AcetylcholinesteraseButyrylcholinesterasePseudocholinesterasePhosphatidyl esterase  <response>: Acetylcholine esterase: AChE Amniotic fluid AChE level is elevated in most cases of open neural tube defects. It has got better diagnostic value than AFP. Reference: D C Duttas Textbook of Obstetrics 7th edition page no 113 