<prompt> In treatment of Parkinsonism with Levodopa dose limiting toxicity isChoriform movementsVomitingsTardive dyskinesiaGiddiness  <response>: B Vomitings ADVERSE EFFECTS 2 HAEMATOLOGICAL Dose limiting toxicity Leucopenia, nadir 21 - 28 days, recovery 28 - 35 days. Thrombocytopenia, nadir 16 days, recovery 21 days. GASTROINTESTINAL Dose limiting toxicity Severe nausea and vomiting, duration 1-12 hours. Aggressive antiemetic prophylaxis is recommended. Nausea is most severe on the first day of multiple day treatment. LOCAL REACTIONS Severe pain at injection site and along vein during administration. Slow infusion rate, and place an ice pack above the injection site. Further dilution of solution may be required. MISCELLANEOUS Hypotension, with single doses of 850 mgm2 or greater. Elevated liver function tests, venous occlusive disease, acute liver dystrophy with fatal thrombosis. Increased blood urea and serum creatinine. Reversible alopecia, facial paraesthesia, facial flushing. Flu-like symptoms e.g. fever, myalgia, and malaise may occur, especially after large, single doses. Onset 7 days, duration 7-21 days. 