<prompt> Acquired symmetric hyper pigmentation of the sun exposed skin of the face and neck, which is strongly associated with pregnancy use of oral contraceptives is called-MelanomaCafe-au-lait spotsFreckleMelasma  <response>: Ref: Burket, Ed. 10th Pg-132 Melasma or Cholasma describes the discrete patches of facial pigmentation which occur in pregnancy and in some women taking oral contraceptives. This pigmentation is seen paicularly in periorbital and perioral region. 