<prompt> A major source of collagen in cirrhosis -Kupffer cellsIto cell Hepatic stellate cellHepatocyteCanalicular cell  <response>: Perisinusoidal stellate cells Ito cells play a role in the storage and metabolism of vitamin A and are transformed into collegen producing myofibroblasts when there is inflamation of the liver.These cells are the major source of collagen in cirrhosis 