<prompt> Diazoxide acts by -Increasing insulin releaseInhibiting insulin releaseInhibiting insulin releaseInhibiting glucagon release  <response>: Ans. is b i.e., Inhibiting insulin release Diazoxide inhibits insulin release from P-cells and causes hyperglycemia. o Its action on ATP sensitive IC channel is opposite to that of sulfonylureas -- opening activation of IC channels -- Hyperpolarization -- inhibition of insulin release. o Other actions which contribute to hyperglycemia a peripheral utilization of glucose b Release of catecholamines It is used in insulinoma. 