<prompt> True about endometrial carcinoma :Predisposed by diabetes mellitus, hypeension and obesityAdenosquamous type is commonestCommonly associated with Ca cervixCommon age group affected is between 20-40 years  <response>: Ans. is a i.e. Predisposed by Diabetes mellitus, hypeension and obesity Endometrial cancer : Most common in nulliparous females.deg Age group : Peak incidence 60 years 6-7h decade most common.deg But in 25 cases can occur before menopause or in young females. Race : Most common in Jews Unlike Ca cervix. Predisposing Factors : Already discussed in detail earlier. A combination of hypeension, diabetes and obesity in association with Endometrial Ca is known as Corpus Cancer Syndrome. Associated diseases : -- Fibroid uterusdeg as it also occurs in Nulliparous females -- Cervical Polypsdeg Pathology : Most common variant is Adenocarcinomadeg known as Endometroid and not Adenosquamous. Only 15-20 of Adenocarcinomas may have squamous differentiation. Histology : Endometrial carcinoma can be distinguished from hyperplasia by : Back to back arrangement of Glandsdeg No intervening stromadeg Desmoplastic stroma Extensive papillary pattern Squamous epithelium differentiationdeg Clinical features : A female of perimenopausal age group 6th -71 decade presents with : Abnormal bleeding 90 cases in the form of metrorrhagia menometrorrhagia, intermenstrual spotting, postmenopausal bledding Discharge 1 PV : -- Brown, watery offensive discharge -- Watery discharge free from blood hydrorrheadeg. Pelvic pressurediscomfo. Referred pain in hypogastrium or both iliac fossae Simpsons pain.Pain tsevere and tends to occur at the same time each day, lasting on 1-2 hrs Impoant. In some older patients, bleeding may not occur due to cervical stenosis. causing hematometrapyometra. Desmoplastic stromadeg Extensive papillary pattern Squamous epithelium differentiationdeg Clinical features : A female of perimenopausal age group 6th -71 decade presents with : Abnormal bleeding 90 cases in the form of metrorrhagia menometrorrhagia, intermenstrual spotting, postmenopausal bledding. Discharge 1 PV : -- Brown, watery offensive discharge -- Watery discharge free from blood hydrorrheadeg. Pelvic pressurediscomfo. Referred pain in hypogastrium or both iliac fossae Simpsons pain. Pain tsevere and tends to occur at the same time each day, lasting on 1-2 hrs Impoant. In some older patients, bleeding may not occur due to cervical stenosis. causing hematometrapyometra. 