<prompt> Persistent organ failure in the setting of acute pancreatitis is defined, when the organ failure lasts for more than:12 hours24 hours48 hours72 hours  <response>: The determinant of the severity of acute pancreatitis during the early phase is the presence and duration of organ failure, if organ failure persists for 48 h. Ref: Gut 2013;62:102-111. doi:10.1136gutjnl-2012-302779. 