<prompt> Which is true regarding ataxia telangiectasia:Increase in AFPIncreases the risk of squamous cell carcinomaAutosomal dominantNone of above  <response>: Increase in alpha-fetoprotein is observed in Ataxia telangiectasia Ataxia-telangiectasia Ataxia-telangiectasia syndrome Louis-Bar syndrome Rare, neurodegenerative, autosomal recessive disorder causing severe disability. Ataxia refers to poor coordination; Telangiectasia refers to small dilated blood vessels. Pas affected: Cerebellum - movement coordination difficulties Immune system - Predisposing to infections. Genetic repair system - Preventing process for repairing DNA - Cancer risk Features: Increased incidence of lymphoma Leukemia Increased alpha-Fetoprotein levels Oculomotor apraxia difficulty in coordination between head eye movements Dysahria REF: HARRISONS 21ST ED 