<prompt> Which of the follow ing drug need not be stopped before surgery -High Dose AspirinWarfarinMetforminDigitalis  <response>: Ans. is d i.e., Digitalis PRE-OPERATIVE MODIFICATION OF PRE-EXISTING DRUGS Drug to be stopped Drug which can continue till the day of surgery o High dose Aspirin -1 week before surgery o Anti anginal except aspirin o Oral anticoagulant - 4 days before and switch over to heparin which is stopped 12 hours prior to surgery o Antiepileptics o Antihypertensives except AT-II antagonists o Levodopa o Oral hypoglycemic metformin - 48 hours before surgery and switch to insulin o Digitalis o Tricyclic antidepressants. o AT-II antagonist Losartan, Valsartan - 1 day prior Low Dose Aspirin o Lithium -48-72 hours before surgery o MAO inhibitors - 3 weeks before surgery 