<prompt> HMB 45 is a tumor marker forNeuroblastomaNeurofibromaMalignant melanomaAngiosarcoma  <response>: Malignant melanoma expresses HMB45 ,S-100 and vimentin HMB 45 is present in melanosome and is more specific S-100 is more sensitive but is non specific also present in LAngerhans cell histiocytosis, neural tumors and sarcomas like Liposarcoma and Chondrosarcoma 