<prompt> Major goals of growth modification always isto maximize skeletal changes and minimize dental changesto maximize skeletal changesto maximize dental changesto maximize dental changes and minimize skeletal changes  <response>: The major goal of growth modification is to maximize skeletal changes and minimize dental changes produced by treatment.Eg: Rapid palatal expansion RPEThe goal of RPE is to expand maxilla by expansion at mid palatal suture skeletal and not just expanding the dental arch by moving the teeth relative to the bone dental. 