<prompt> Platelet transfusion is indicated in all ExceptDilutional thrombocytopeniaITPAplastic anemiaDIC  <response>: The treatment of ITP uses drugs that decrease reticuloendothelial uptake of the antibody-bound platelet, decrease antibody production, andor increase platelet production. The diagnosis of ITP does not necessarily mean that treatment must be instituted. Patients with the platelet count 30,000mL appear not to have increased moality related to the thrombocytopenia.Prednisone at 1 mgkg is the traditional treatment in patients without significant bleeding symptoms, severe thrombocytopenia 5000mL, or signs of impending bleeding such as retinal hemorrhage or large oral mucosal hemorrhages.For patients with severe ITP andor symptoms of bleeding, hospital admission, and combined-modality therapy is given using high-dose glucocoicoids with IVIgG or anti-Rh0D therapy and, as needed, additional immunosuppressive agents. Rituximab, an anti-CD20 B cell antibody, has shown efficacy in the treatment of refractory ITP, although long-lasting remission only occurs in approximately 30 of patientsReference: Harrison;s Principles of Internal Medicine; 19th edition; Chapter 140; Disorders of Platelets and Vessel wall 