<prompt> A 65-year-old male patient complains of loss of libido and is found to have a low free and total testosterone level. Treatment is commenced with testosterone supplemental therapy. What is the next step in management after testosterone administration?Check PSA levelsTestosterone levels are decreasedDecrease in size of benign prostatic tissue lesions occursDecrease in size of prostatic cancer occurs  <response>: PSA levels can increase because both benign and malignant prostatic tissue are sensitive to testosterone hormonal therapy. There is increased prostatic growth with elevation of PSA and possible polycythemia. 