<prompt> PRSS1 gene is on?Chr 20qChr 17pChr 7qChr 1p  <response>: Ans. c Chr 7qRef: Robbins 9thpg 166; 8thpg 166Hereditary pancreatitis is characterized by recurrent attacks of severe acute pancreatitis often beginning in childhood and ultimately leading to chronic pancreatitis.The disorder is genetically diverse, but the shared feature of most forms is a defect that increases or sustains the activity of trypsin. Three genes implicated in hereditary pancreatitis are PRSS1, SPINK1, and CFTR.Most hereditary cases are due to gain-of-function mutations in the trypsinogengene also known as PRSS1 on chr 7q34 