<prompt> A 72-year-old man is newly diagnosed with bullous pemphigoid. Which of the following is the most appropriate next step in the management?plasmapheresislow-dose prednisone 10-20 mgdayhigh-dose prednisone 50-100 mgdayazathioprine 150 mgday  <response>: Severe cases require systemic steroids, often with the addition of azathioprine. Dapsone is useful in mild cases, and occasionally in very mild cases or for local recurrences topical glucocorticoid therapy will suffice. 