<prompt> glipizide differs from chlorpropamide in that it:Is more potentIs longer actingDoes not lower blood sugar in nondiabetic subjectsIs less prone to cause hypoglycemic reaction  <response>: Ref: KDT 6e p266 Second generation like glipizide sulfonylureas are more potent than first generation agents like chlorpropamide. Chlorpropamide is the longest acting sulfonylurea. Sulfonylureas can cause hypoglycemia even in non-diabetics due to release insulin. 