<prompt> Which of the following is not a feature of megaloblastic anaemia: September 2010ThrombocytopeniaMegakaryocytesReticulocytosisHowell-jolley bodies  <response>: Ans. C: Reticulocytosis The blood film suggestive of vitamin B12 deficiency includes: Decreased red blood cell RBC count and hemoglobin levels. Increased mean corpuscular volume MCV, 95 fl and mean corpuscular hemoglobin MCH Normal mean corpuscular hemoglobin concentration MCHC, 32-36 gdL The reticulocyte count is decreased due to destruction of fragile and abnormal megaloblastic erythroid precursor. The platelet count may be reduced. Neutrophil granulocytes may show multisegmented nuclei senile neutrophil. Anisocytosis increased variation in RBC size and poikilocytosis abnormally shaped RBCs. Macrocytes larger than normal RBCs are present. Ovalocytes oval-shaped RBCs are present. Howell-Jolly bodies chromosomal remnant also present 