<prompt> Definitive laboratory diagnosis of acute pancreatitis is done by:Serum AmylaseSerum LipaseHyperglycemiaHypercalcemia  <response>: Answer is B Serum Lipase Serum lipase elevation is the most specific laboratory test for establishing a diagnosis of Acute Pancreatitis A three fold elevated serum lipase value is usually diagnostic of acute pancreatitis - Harrison Serum Lipase levels and serum amylase levels are both used to establish the diagnosis of acute pancreatitis An elevated serum Lipase level is more specific for pancreatitis than- a serum amylase level because many other pathologic conditions may present with an elevated amylase level. Serum lipase is therefore the single best answer of choice. 