<prompt> Family of Toll-like receptors TLRs are?Most impoant for oncogene activation by virus and plays impoant role in cancerEssential for glucose homeostasisMost impoant for entry of retrovirus into the immune cellsMost impoant receptors for microbial products to initiate acute inflammation  <response>: Toll-like receptors TLRs are a class of proteins that play a key role in the innate immune system. They are single, membrane-spanning, non-catalytic receptors usually expressed on sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes.They are the Most impoant receptors for microbial products to initiate acute inflammation. Ref - Harrisons internal medicine 20e p1067,2511 