<prompt> Drug of choice for acute severe asthma is: September 2006Sho acting beta 2 agonistsLong acting beta 2 agonistsOral theophyllineInhaled ipratropium bromide  <response>: Ans. A: Sho acting beta 2 agonists Severe asthma Continuous symptoms; activity limitation; frequent exacerbationshospitalization requires: Regular high dose of inhaled steroid 800-2000 microgram day through a large volume spacer device and inhaled long acting beta2 agonist Salmeterol. Additional treatment with one or more of the following: Leukotriene antagonistSustained release oral theophylline oral beta2 agonist inhaled ipratropium bromide. Rescue treatment with sho acting inhaled beta2 agonist In patients not adequately controlled or those needing frequent emergency care-institute oral steroid therapy. 