<prompt> In which of the following types of Carcinoma Breast, Comedo growth pattern in seen ?Ductal carcinoma in situMedullary carcinomaLobular carcinoma in situInfiltrating lobular carcinoma  <response>: - Historically, ductal carcinoma in situ intraductal carcinoma has been dividedinto five architectural subtypes : comedocarcinoma, solid, cribriform, papillary and micropapillary.Comedocarcinoma is characterized by solid sheets of pleomorphic cells with high grade nuclei and central necrosisThe necrotic cell membranes commonly calcify and are detected on mammography as clusters of linear and branching microcalcifications. 