<prompt> Predisposing factors for coronary aery disease include all exceptHomocysteinemiaIncreased lipoprotein BIncreased fibrinogenIncreased plasminogen activator inhibitors 1  <response>: Ref Harrison 19 th ed pg 1579 The major risk factors for atherosclerosis high levels of plasma low-density lipoprotein , low plasma high-density lipoprotein , cigarette smoking, hypeension, and diabetes mellitus disturb the normal functions of the vascular endothelium. 