<prompt> Oxygen hemoglobin dissociation curve shifts to right in all of the following conditions EXCEPT:HyperthermiaDecreased pHDecreased HIncrease CO2  <response>: Ans. C Decreased HRef: Ganottg, 25th ed. pg. 640-641OXYGEN HEMOGLOBIN DISSOCIATION CURVE Oxygen- hemoglobin dissociation curve is sigmoid S shaped because binding of one oxygen molecule to heme increases the affinity of second heme molecule for oxygen and so on.Factors affecting affinity of Hb for oxygen and causing the shift of curve are:Left shiftRight Shift This means the affinity of oxygen to Hb is increased and oxygen is bound more tightly to hemoglobin This means the affinity of O2 to Hb is decreased which favours release of oxygen to tissue. Factors leading to left shift are Alkalosis or pH pCO2 CO2 content of blood Temperature Hypothermia 2,3 DPG Factors leading to right shift are: Acidosis or pH PCO2 CO2 content of blood Temperature Hypothermia 2,3 DPG 