<prompt> 68-years-old man weighing 60 kg has plasma creatinine 3mgdL. What will be creatinine clearance?10203040  <response>: By Cockcroft Gault formula Factors influencing 1. Body wt. - Assumed to be do muscle mass - Muscle - creatine - creatinine 2. Age - with advancing age, number of functional nephrons decrease Cockcroft gault formula unreliable in: - 1. Obesity 2. Pregnancy 