<prompt> p-ANCA is sensitive and specific for-Post streptococcal glomerulonephritisIdiopathic crescentic glomerulonephritisDiffuse glomerulosclerosisWegeners granulomatosis  <response>: Antineutrophil cytoplasmic antibodies ANCAANCA are a heterogeneous group of autoantibodies directed against antigens which are found within the primary granules of neutrophil and in the lysosomes of monocytes and in ECs.The description of these autoantibodies is based on the immunofluorescence pattern of staining of ethanol-fixed neutrophils. With immunofluorescence two principal patterns are recognized:1. Cytoplasmic c-ANCA:This shows cytoplasmic localization of the staining and the target antigen for this type of autoantibody is proteinase-3 PR3, a neutrophil granule constituent.2. Perinuclear staining p-ANCA This shows perinuclear staining and the target antigen here is myeloperoxide MPO. Remember that either of these antibodies may occur in a patient with ANCA associated small vessel vasculitis buti cANCA Typically found inWegeners granulomatosisii pANCA Typically found inMicroscopic polyangiitisChurg-Strauss syndromeIdiopathic crescentic glomerulonephritisGoodpastures syndrome.pANCAs are also associated with certain non-vasculitic entities such as certain rheumatic and nonrheumatic autoimmune diseases, Inflammatory bowel diseases, certain drugs, infections such as endocarditis and bacterial airway infection in patients with cystic fibrosis. 