<prompt> Burkitts lymphoma is malignancy ofB.cellsT cellsAntigen presenting cellsNull cells  <response>: A B-cell 452-Baveja 4th 566-Ananthanarayan 9thBurkitts lymphoma - a malignant neoplasm of B- lymphocytes tumour of jaw EBV has affinity for lymphoid tissue. The virus especially affects B-lymphocytes. EBV infected B lymphocytes are transformed in such a way that they multiply continuously.B -cells B. Cells are part Of adaptive immunity B. cells constitute 10 to 20 of the circulating peripheral lymphocytes B. cells originate as well as mature in bone marrow contrast to T- cells IgM and IgD present on the surface of all native B. cells After antigenic stimulation ,B. cells form plasma cells that secrete immunoglobulins B. cells bind to sheep erythrocytes coated with antibody and complement, forming EAC rosette T. cells binds to sheep erythrocytes CD2 forming SRBC or E rosette EB V is a polyclonar activator of B cells leads to the production of antibodied to host cells and viral proteins AUTOIMMUNITYDuring development T cells undergo both positive selection and negative selection, while B cells undergo only negative selectionEBV associated malignancies Burkitts lymphoma Hodgkins disease mixed cellularity type T. cell lymphoma Gastic carcinoma Angiocentric nasal NKT cell immunoproli ferative lesions Angio-immuno-blastic lymphadenopathy Nasopharyngeal carcinoma T onsillar carcinoma Thymoma CNS lymphoma in AIDS and transplant recipientOther associated nonmalignant conditions Oral hairy leukoplakia in AIDS Patients Chromic fatigue syndrome X - linked lymphoproliferative syndrome Duncans syndrome. 