<prompt> True about diabetes in pregnancy are all except:Glucose challenge test is done between 24-28 weeks50 gm of sugar is given for screening testInsulin resistance improves with pregnancyDiabetes control before conception is important to prevent malformation  <response>: Ans. is c, i.e. Insulin resistance improves with pregnancyRef. Dutta 7e, p 282 for option a, b, 283 for option c and 285 for option d; Fernando Arias 3e, p 440, 442, 443In pregnancy, the insulin sensitivity decreases i.e. insulin resistance increases as the gestation advances mainly due to anti insulin signals produced by placenta mainly human placental lactogen.Congenital malformations in a diabetic mother occur within first 8 weeks of gestation when most women are just beginning prenatal care. Therefore preconceptional counselling is very essential in a diabetic motherScreening for diabetes during pregnancy is done by glucose challenges test at 24-28 weeks of pregnancy. 