<prompt> Regarding cholecystokinin-pancreozymin CCK-PZ, all are true except Repeat 2007 Q 42Increases pepsinogen secretionDelays gastric emptyingGall bladder contractionIncreases pancreatic secretion  <response>: Ans: a Pepsinogen secretion is increased by gastrin and not by CCK-PZPepsinogen secretion is increased by gastrin and not by CCK-PZ.Important points on GI hormones: CCK-PZSecretionGastrinFromJejunum I cellsUppersmall intestine S cellsAntral portion of stomach G cellsStimulus- Protein digestion products- Protein digestion productsLuminal- protein products, distention- Fatty acids- Acids bathing mucosaNeural- vagal discharge GRPBlood- calcitonin, epinephrineAction1 Delays gastic emptying Pyloric sphincter contra.1 HCO3- rich pancreatic juice1 Stimulate gastric acid pepsin2 duodenal emptying2 Augments action of CCK2 Trophic to stomach mucosa3 motility of intestine colon3 gastric acid secretion3 Gastric motility4 pancreatic secretion enzyme rich4 Pyloric sphincter contr.4 Stimulate insulin secretion5 Stimulate secretion6 GB contraction7 glucagon secretion8 Trophic to pancreas 