<prompt> Which of the following is most characteristic of the brain in patients with Alzheimers diseasePigmentary degeneration in hippocampusDemyelination in cerebral cortexPosterior column degenerationNeuronal loss in cerebral cortex  <response>: Most prominent feature of alzheimers disease is neuronal loss, fibrillary tangles, loss of synapses and amyloid plaque formation. 