<prompt> All are true about gastrinomas except:Most gastrinomas 50-70 are present in the duodenumAbout 10 of gastrinomas are malignantMetastatic spread to lymph nodes and liverCauses peptic ulcer disease with diarrhea  <response>: Most gastrinomas 50-70 are present in the duodenum, about 60-90 of gastrinomas are malignant with metastatic spread to lymph nodes and liver. Distant metastases to bone occur in 12-30 of patients with liver metastases. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 3065 