<prompt> Which of the following is not due to genetic mutation -Diabetes mellitus type IICystic fibrosisHemophiliaAlpha 1 antitrypsin deficiency  <response>: Ans. is a i.e,, Diabetes meilitus type II o Disorders with multifactorial inheritance : The multifactorial disorders result from the combined actions of environmental influences and two or more mutant genes having additive effects.o Multifactoriai disorders are:Cleft lipcleft palateCoronary heart diseaseCongenital heart diseasesHypertensionDiabetes meilitus type IIGoutPyloric stenosiso Other options in question i.e. hemophilia, alpha-1 antitrypsin deficiency, and cystic fibrosis are due t genetic mutations.Note: Diabetes insipidus is X linked recessive disorder due to genetic mutation. 