<prompt> Regarding PCOS and hyperinsulinaemiaHyperinsulinaemia is observed in about 40 to 80 of women with PCOSMetformin has many other health benefitsMetformin causes hypoglycaemia in normoglycaemic womenHyperinsulinaemia stimulates hepatic synthesis of SHBG  <response>: In PCOSHyperinsulinemia is seen in 50-70 cases of PCOSInsulin induces LH to cause thecal hyperplasia and secrete androgensHyperandrogenism lowers the level of hepatic sex hormone binding globulinMetformin treats the root causes, rectifies endocrine and metabolic function, improves fertility rate, used as insulin sensitiserIt reduces insulin level, delays glucose absorption, liver production of glucose and improves peripheral resistanceMetformin do not cause hypoglycemia in a normoglycemic women 