<prompt> Mirels criteria is developed for the evaluation ofRisk of fatigue fractureSeverity of osteoporosisRisk of pathological fractureSeverity of neurological defecit  <response>: Mirels Criteria For Risk of Pathological Fracture: 1 Mirels developed a scoring system based on, the presence or absence of pain,the size, location, and radiographic appearance of the lesion to quantify the risk of impending pathological fracture in malignant lesion 2 So patients with maximum risk of pathological fracture are having lytic peritrochantric lesion involving 23 diameter with severe pain 3 Patients with 7 score are observed, but those with 8 or more should have prophylactic internal fixation. Pathological Fractures may occur even with normal stresses if the bone has been weakened by a change in its structure Causes: osteoporosis, osteogenesis imperfecta , Pagets disease, bisphosphonate therapy or through a lytic lesion e.g. a bone cyst or a metastasis. FDG-PET CT is the gold standard for bone Metastasis. It occurs in abnormal bones. Mostly in elderly people. Fractures can be single or multiple occurs after tril injury. Pain in the case of a pathological fracture usually precedes the fracture. Pain can occur at the site before the fracture 