<prompt> Adequacy of D-penicillamine treatment in wilson is monitored by measuring the:24 hour urinary copperSerum ceruloplasminDisappearance of KF ringSerum copper level in the fasting state  <response>: D-Penicillamine treatment in wilson disease: Adequacy of treatment is monitored by measuring 24-hour urinary copper excretion while on treatment. The most impoant sign of efficacy is a maintained clinical and lab improvement. Serum ceruloplasmin decrease after initiation of treatment. Ref: Journal of Hepatology 2012 vol. 56 671-685. 