<prompt> A 30 year old lady presents to the outpatient department with an erythematous butterfly rash on her cheeks. Which of the following antibodies should be assayed initially for her suspected condition:Anti-ds-DNAAnti-Ro-AntibodyAnti-Centromere-AntibodyAnti-mitochondrial-Antibody  <response>: Ans. a Anti-ds-DNARef: Robbins 9thpg 218-221The given clinical features are suggestive of SLE;Specific test for diagnosis of SLE is anti ds DNA;This antibody also correlates with disease activity, nephritis, vasculitis.So Anti-dsDNA should be initially assayed in this case. 