<prompt> Bioavailability ?Area of oral area of IVArea of IV area of oralArea of oral area of IV x 100Area of IV area of oral x 100  <response>: Ans. is c i.e., Area of oral area of IV x 100 Bioavailability Refers to the rate and extent of absorption of drug from a dosage form as determined by its concentration-time curvein blood or by its excretion in urine. It is the measure of fraction F of drug, which reaches the systemic circulation in unchanged form. Bioavailability of a drug given by i.v.route is 100. So the bioavailability of drug dosage form is determined by comparing it with the i.v.route. 