<prompt> Symptomatic neonatal CNS involvement is most commonly seen in which group of congenital intrauterine infection -CMV and toxoplasmosisRubella and toxoplasmosisRubella and HSVCMV and syphillis  <response>: Ans. is c i.e., Rubella and HSV o CNS involvement is common feature from infection with all agents of TORCH group. o With most infections, patients remain asymptomatic in neonatal period and serious neurological consequences become apparent after neonatal period. o CNS manifestations that are symptomatic in neonatal period are most commonly seen in - i HSV 76-100 ii Rubella 26-60 o CMV, toxoplasma, and syphillis become symptomatic in less than 1045 of cases. 