<prompt> Concerning fibroids:Use of GnRH analogues cause permanent reduction in sizePregnancy following myomectomy is about 80Recurrence rate following myomectomy is about 30Growth factors IGF-1, EGF stimulates myoma to grow  <response>: Option a: Incorrect as regrowth of myoma occurs after 3 months of GnRH therapyOption b: Is also incorrect as pregnancy rate following myomectomy is 5060 and not 30.Option c: Recurrence rate is 1, 10 and not 30 hence it is also incorrect.Option d: Epidermal growth factor EGF, insulin like growth factor IGF 1, transforming growth factor TGF, stimulate the growth of the leiomyoma either directly on via estrogen Dutta Gynae 6thed p 272. Hence option d is correct. 