<prompt> Impaired function of Aquaporin results inNephrogenic DILiddle syndromeCystic fibrosisBaer syndrome  <response>: ADH acts V2 receptors on DCT casuing facultative reabsorption of water by inseing Aquaporin -2 channels into apical luminal side . Nephrogenic DI-defect in aquaporins BATER SYNDROME - Autosomal recessive Defect inNa-K-2Cl cotranspoer, Cl channel ROMKin loop of Henle LIDDLE SYNDROME - Gain of function of epithelial Na channel ENaC Cystic fibrosis - CH-7 defect in CFTR gene - causing defect in transmembrane chloride ion regulation. 