<prompt> Mantle cell lymphoma showsCD 5, CD 25 -CD5, CD 10CD5, CD 23CD5, CD 23 -  <response>: Markers of germinal center B cells: CD19, CD20, CD10, and BCL-6.The lymphomas which arise from germinal center B cellsare follicular lymphoma, diffuse large B cell lymphoma, and Burkitt lymphoma. Mantle cell lymphoma arise from mantle zone surrounding germinal center which is usually CD10 negative. Hence option B excluded.Salient features of NHL TypeImmunophenotypeDLBCLSIg, CD10, CD 5, Ki6790Follicular lymphomaSIg, CD10, CD 5-, CD 23, BCL-2MALT lymphomaSIg, CD10-, CD 5-, , CD 23-Small lymphocytic lymphomaSIg weak, CD10-, CD 5, CD 23,Mantle cell lymphomaSIg, CD10-, CD 5, CD 23-, Cyclin D1Burkitt lymphomaSIg, CD10, CD5-, Ki6799Ref: Robbins 8e p605-608, 612-613, 7e p675-678, Wintrobes 12e p2223 