<prompt> Thiopentone is CI in:Acute intermittent porphyriaBronchial AsthmaBothNone  <response>: A i.e. Acute intermittent porphyria - In porphyria AIP, barbiturates eg thiopentone, methohexital thiamylal, etomidate, pentazocine and ropivacaine are avoided contraindicatedQ whereas diclofenac, ketorolac, phenacetin, tilidine, chlordiazepoxide, nitrazepam, hydralazine, nifedipine, and phenoxybenzamine are used with extreme caution only. Barbiturate Thiopentone induces aminolevulenic acid synthetase formation of porphyrin which may precipitate actue intermittent or variegate prophyriaQ. ; so it is contraindicated in porphyria.Q - Due to cholinergic nerve stimulation, histamine release or direct bronchial smooth muscle stimulation, barbiturates may cause bronchospasm; which would be preventable by pretreatment with atropine, so it is not CI in asthma. 