<prompt> All are true about scleroderma crisis except?Accelerated hypeensionOnion skinning of renal vesselsAnti - centromere antibody is a positive predictor of diseaseACE inhibitors reduced moality rate  <response>: Scleroderma crisis occurs in 12 of cases with systemic sclerosis. It is characterised by accelerated hypeension and a rapid decline in kidney function. Histopathological examination shows arcuate aery intimal narrowing and medial proliferation. This is characteristically called onion skinning. Anti-U3-RNP may identify the young patients at risk for scleroderma crisis. Anti-centromere is a negative predictor for scleroderma crisis. Maximum moality in scleroderma occurs due to Pulmonary aery hypeension and pulmonary fibrosis. NOTE : In Scleroderma renal crisis - Prompt treatment with an ACE inhibitorcan reverse acute renal failure. ACE inhibitors should be used even if the patient requires dialysis suppo. MC cause of death in Systemic Sclerosis : Pulmonary Aerial Hypeension 