<prompt> Which drug is not included in RNTCP regime for MDR TB -CycloserineEthionamideLevofloxacinPAS  <response>: Ans. is d i.e., PAS Treatment of multidrug resistance MDR TBo MDR-TB is defined as resistance to at least both IIS H and rifampicin. Previously it was classified as Category IV under DOTS DOTS-PLUS.o The treatment is given in two phases, the intestive phase IP and the continuation phase CP. The total duration of treatment for regimen for MDR-TB is 24-27 months, depending on the IP duration,o Treatment regimen comprises :-Intensive phase 6-9 months : Six drugs : Kanamycin Km, levofloxacin Lvx, ethionamide Eto, pyrazinamide Z, ethambutol E, and cycloserine Cs.Continuation phase 18 months : Four drugs : Levofloxaxcin, ethionamide, ethambutol and cycloserine,o Total duration of treatment is 24-27 months.Treatment of extensive drug resistance XDR TBo XDR-TB is defined as resistance to any fluoroquinolone and at least one of the following three second-line drugs capreomycin, kanamycin, amikacin, in addition to muitidrug resistance,o The Regimen for XDR-TB would be of 24-30 months duration, with 6-12 months Intensive Phase IP and 18 months Continuation Phase CP.o Regimen is :-Intensive phase 6-12 months : Seven drugs : Capreomycin, PAS, moxifloxacin. high dose INH. clofazimine, Linezolid, amoxyclav.Continuation phase 18 months : Six drugs : PAS, moxifloxacin, high dose INH, clofazimine, linezolid, amoxyclav. 