<prompt> Increase in MCHC is associated withIron deficiency anemiaMegaloblastic anemiaAnemia of chronic diseaseHereditary spherocystosis  <response>: Ans is d i.e. Hereditary spherocystosis Mean cell hemoglobin concentration MCHC is the average concentration of hemoglobin in a given volume of packed red blood cells, expressed in grams per deciliter. Normal value is 33-37 gmdlMCHC is increased in hereditary spherocytosis, not because of increased hemoglobin, but due to decerase volume of spherocytes.MCHC is decreased in microcytic hypochromic anemiairon deficiency anemia anemia of chronic disease.MCHC remains normal in megaloblastic anemia. 