<prompt> Beaded ribs with epiphysial swelling is a feature of:Vit D deficiencyVit A deficiencyVit C deficiencyVit K deficency  <response>: Rickets is characterized by the continued formation of the collagen matrix of bone, but incomplete mineralization results in soft, pliable bones. In osteomalacia, demineralization of pre-existing bones increases their susceptibility to fracture. Insufficient exposure to daylight andor deficiencies in vitamin D consumption occur predominantly in infants and the elderly. Vitamin D deficiency is more common in the northern latitudes, because less vitamin D synthesis occurs in the skin as a result of reduced exposure to ultraviolet light. Loss-of-function mutations in the vitamin D receptor result in hereditary vitamin D-deficient rickets.Vitamin D deficient rickets leads to epiphyseal swelling with beaded ribs known as Rachitic rosary.Key Concept:Vitamin D deficient rickets leads to epiphyseal swelling with beaded ribs known as Rachitic rosary.Ref: Lippincotts illustrated reviews for biochemistry, 7th edition. 