<prompt> POEMS Syndrome includes all, EXCEPT:PolyneuropathyOrganomegalyEndocrinopathyMultiple sclerosis  <response>: The features of this syndrome are polyneuropathy, organomegaly, endocrinopathy, multiple myeloma, and skin changes POEMS. Patients usually have a severe, progressive sensorimotor polyneuropathy associated with sclerotic bone lesions from myeloma. Polyneuropathy occurs in 1.4 of myelomas, but the POEMS syndrome is only a rare subset of that group. Unlike typical myeloma, hepatomegaly and lymphadenopathy occur in about two-thirds of patients, and splenomegaly is seen in one-third. Ref: Harrisons principle of internal medicine 17th edition, Chapter 106. 