<prompt> Emesis receptor is5HT15HT25HT35HT4  <response>: ANSWER: C 5HT3REF: Goodman Gillman manual of pharmacology and therapeutics 2008 edition, page 646Iheprocessofnauseaandvomiting appears to be coordinated by a central emesis center in the lateral reticular formation of the mid-brainstem adjacent to both the chemoreceptor trigger zone CTZ in the area postrema AP at the bottom of the fourth ventricle and the solitary tract nucleus STN of the vagus nerve.The lack of a blood-brain barrier allows the CTZ to monitor blood and cerebrospinal fluid constantly for toxic substances and to relay information to the emesis center to trigger nausea and vomitingThe CTZ has high concentrations of receptors for serotonin 5-HT3, dopamine D2, and opioids, while the STN is rich in receptors for enkephalin, histamine, and ACh, and also contains 5-HT3 receptors.The most effective agents for chemotherapy-induced nausea and vomiting are the 5-HT3 antagonists and metoclopramidePharmacological view of emetic stimuli 