<prompt> A 23 year old female presents to the clinic with 5 weeks history of amenorrhea. Pregnancy test done in her was found to be positive and on examination Palmer sign is present. What does Palmers sign indicate?Pulsation in lateral fornixSoftening of uterusRhythmic contraction of uterusBluish colouration of vagina  <response>: Palmers sign refers to the regular and rythmic uterine contractions which is elicited during bimanual examination. It is present as early as 4-8 weeks. Osianders sign refers to the feeling of increased vaginal pulsation felt through the lateral fornices at 8th week of gestation. Jacquemiers sign or Chadwicks sign refers to the dusky hue of the vestibule and anterior vaginal wall visible at about 8th week of pregnancy. Goodells sign refers to softening of the cervix as early as 6th week of gestation. Ref: Textbook of Obstetrics By D.C Dutta, 6th edn, page 65 