<prompt> The sequence that targets protein to lysosmoesGlucose 6 - phosphateMannose 6 - phosphateRibose 5 - PhosphateFructose 1 - phosphate  <response>: Mannose 6 - phosphate acts as a tag for the proteins to reach lysosomes. Defects in the process of tagging this sequence to protein result in I - Cell disease. 