<prompt> A 25-year old male had pigmented macules over the plam, sole and oral mucosa. He also had anemia and pain in abdomen. The most probably diagonosis is-Albrights syndromeb Cushings syndromePeutz-Jeghers syndromeIncontinentia pigmenti  <response>: Peutz-Jeghers syndrome PJS is an autosomal dominant inherited disorder characterized by intestinal hamaomatous polyps in association with a distinct pattern of skin and mucosal macular melanin deposition. Ref Harrison 20th edition pg 576 