<prompt> Lymph node biopsy of an AIDS patient shows:March 2009Wahin-Finkeldey cellsMarked follicular hyperplasiaMoth-eaten appearanceAll of the above  <response>: Ans. D: All of the aboveHistopathology of HIVFlorid reactive hyperplasia-may be:- Collections of monocytoid B cells in sinuses- Neutrophils- Features of dermatopathic lymphadenopathyOften reactive germinal centers show follicle lysis:i.e. invagination of mantle lymphocytes into germinal centers associated with:- Disruption of centers moth-eaten appearance- Distinctive clustering of large follicular center cells resulting appearance termed explosive follicular hyperplasiaOccasional polykaryocytes:- Wahin-Finkeldey cells- May be multinucleated form of follicular dendritic cellElectron microscopy:- Sometimes prominent follicular dendritic cells exhibit alterations of their fine processesInterfollicular tissue may show prominent vascular proliferation: vague resemblance to Castlemans disease- These areas and subcapsular region may reveal earliest signs of Kaposis sarcoma- Sometimes advanced lymphocyte depletion: may be abnormal regressively transformed germinal centers 