<prompt> Beta-glucosidase is defective in which disease?Gauchers diseaseTay-Sachs diseaseGalactosaemiaDM  <response>: Ans. a Gauchers disease. Ref: Harper, Biochemistry, 25th ed., 267Sphingolipidoses DiseaseInheritanceEnzymeCNS involvementVisceral involvement1FabryXLRAlpha-galactosidase-2KrabbesARBeta-galactosidasebilateral thalami3FarberARCeramidase--4GaucherARBeta-Glucosidase-5MetachromaticleukodystrophyARAryl sulfatase Diffuse White matter-6Niemann-PickARSphigomyelinase7Tay-SachsARHexosaminidase A-8SandhoffARHexosaminidase A, B 