<prompt> Cell-matrix adhesions are mediated by?CadherinsIntegrinsSelectinsCalmodulin  <response>: The cell adhesion molecules CAMs are classified into four main families:- Immunoglobulin family CAMs Cadherins Integrins: bind to extracellular matrix ECM proteins such as fibronectin, laminin, and osteopontin providing a connection between cells and extracellular matrix ECM Selectins 