<prompt> 13 year old female having sudden onset high grade fever with delirium. CT. finding so involvement of limbic system medial temporal lobe - Dx isSubarachnoid hemorrhageHerpes simplex encephalitisPyomeningitisCerebral malaria  <response>: Ans. is b i.e., Herpes simplex encephalitis Herpes simplex encephalitis Acute necrotising infection involving frontal, temporal lobe limbic system. Feature Non specific - fever, headache, nuchal rigidity. convulsion, altered sensorium. Confirmed by CSF examin radio imaging. Treatment suppoive and Acyclovir 