<prompt> Jod-Basedow phenomenon refers to which of the following?Iodine excess causing suppression of TSHIodine excess causing hypehyroidismIodine excess causing transient decrease in thyroid hormone productionIodine excess causing regression of MNG  <response>: It is named for Karl Adolph von Basedow, a German physician and the German word for iodine, jod. It is the opposite of the Wolff-Chaikoff effect. Amiodarone can cause thyrotoxicosis that may be caused by either a Jod-Basedow effect from the iodine load, in the setting of MNG or incipient Graves disease. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Table 341-6, Causes of Thyrotoxicosis, Pages 2922, 2930-31. 