<prompt> All of the following are false regarding Vacuum assisted closure Except -Due to negative pressure , bacterial counts decrease and cell proliferation increases in the wound.Continuous pressure of 125 mm hg is applied.It causes interstitial edema , thereby increasing blood flow and better healing.Suitable to be used over malignancy if present in wound.  <response>: VACUUM ASSISTED CLOSURENEGATIVE PRESSURE WOUND THERAPYNPWT NPWT promotes wound healing by applying a vacuum through a special sealed dressing. Continued vacuum draws out the fluid interstitial fluid from wound and increase blood flow to the area. As a result, bacterial counts decrease and cell proliferation increases, thereby creating a suitable bed for graft or flap cover. Intermittent negative pressure of -125 mm Hg appears to hasten debridement and formation of granulation tissue in chronic wounds and ulcers. Contraindications for NPWT Use Malignancy in the wound Untreated osteomyelitis Non-enteric unexplored fistula Necrotic tissue with eschar 