<prompt> Risk factors for the development of critical limb ischemia include all exceptDiabetesHyperlipidemiaModerate alchol intakeHyperhomocysteinemia  <response>: .Critical Limb Ischaemia It is persistently recurring ischaemic rest pain for 2 weeks or ulceration or gangrene of the foot or toes with an ankle systolic pressure 50 mmHg or toe systolic pressure 30 mmHg.If patient continues to smoke, disease progresses into the collaterals, blocking them eventually, leading to severe ischaemia and is called as decompensatory peripheral vascular disease. It is presently called as critical limb ischaemia. It causes rest pain, ulceration, gangrene. ref:SRB;s manual of surgery,ed 3,pg no 152 