<prompt> Olympian f-ow and I hi:odesCMV inclusion diseaseEctodermal dysplasiaCongenital syphilisHyper IgE syndrome  <response>: Ans. c. Congenital syphilis Clinical Presentation of Syphilis Early Congenital Syphilis: Snuffles rhinitisQ is earliest feature. Lesions are vesicobullousQ, and snail track ulcers on mucosa Clinical Presentation of Syphilis Late Congenital Syphilis: Characterized by Hutchinsons triad interstitial keratitis 8th nerve deafness Hutchinsons teeth i.e. pegged central upper incisorsQ Saddle nose, sabre tibia, mulberry molarsQ Bull dogs jaw protrusion of jaw Rhagadesdeg linear fissure at mouth, nares Frontal bossing, hot cross bun deformity of skull Cluttons jointdeg painless swelling of joints, most commonly both knee Palatal perforationdeg Higaumenakis sign periostitis leads to unilateral enlargement of sterna end of clavicle Primary Syphilis: Painless, indurated, nonbleeding, usually single punched out ulcer hard chancreQ Painless, rubbery shotty lymphadenopathy Secondary Syphilis: Bilateral symmetrical asymptomatic localized or diffuse mucocutaneous lesiondeg macule, papule, paulosquamous and rarely pustule Non-tender generalized lymphadenopathyQ Highly infectious condylomata late, in warm moist interiginous areas Moth eaten alopecia, ahritis, proteinuriaQ Teiary Syphilis: Gumma, neurosyphilistabes dorsalisQ Ostitis, periostitis Aoitis, aoic insufficiency, coronary stenosis and nocturnal anginaQ 