<prompt> Which of the following cell types is not a target for initiation and maintenance of HIV infection?CD4 T cellMacrophageDendritic cellNeutrophil  <response>: Selective tropism for CD4 molecule receptor. gp120 envelope glycoprotein of HIV has selective tropism for cells containing CD4 molecule receptor on their surface; these cells most impoantly are CD4 T cells T helper cells; other such cells include monocyte-macrophages, microglial cells, epithelial cells of the cervix, Langerhans cells of the skin and follicular dendritic cells. Initially, HIV on entering the body any route described above has tropism for macrophages M-tropic while later it becomes either dual tropic or T-tropic only and thus affects mainly CD4 T cells which are the main target of attack by HIV. Ref: Harsh Mohan - Textbook of Pathology, 6th Edition.page no.69 