<prompt> Karyotype of klienfelter syndrome is?47XXY45XO46XXY45XXX  <response>: Ans. is a i.e., 47XXYKlinefelter syndromeKlinefelter syndrome is the most common chromosomal disorder associated with male hypogonadism and infeility.It is defined classically by a 47, XXY karyotype with variants demonstrating additional X and Y chromosomes.Other variants can have 48 XXXY, rarely 49 XXXY or mosaics can be there with some cells containing normal 46,XY and others 47, XXY.Classically, it results from meiotic non-dysjunctionof sex chromosomes 40 during spermatogenesis and 60 during oogenesis. Mostly, non-dysjunctionoccur during lstmeiotic division. 