<prompt> Major regulator of interdigestive myoelectric complexesVIPGIPMotilinNeurotensin  <response>: C i.e. Motilin - Glucagon derivative GLP- 1 7-36 amide most potent gastric inhibitory peptide GIP also known as glucose -dependent insulinotropic polypeptide gastrin, CCK, secretin and glucagon stimulates insulin secretionQ. But only GLP-1 7-36 amide GIP stimulate insulin secretion when adminstered in dose that produce blood levels comparable to those produced by oral glucose. - Motolin is secreted by entero chromaffin cells M0 cells in stomach, small intestine and colon during fasting. It is released cyclically so 1 ed levels at intervals of 90- 100 minutes in a fasted person which stimulates waves of gastrointestinal motality called myoelectric interdigestive cmplexes MIC. Erythromycin binds to motolin receptors so its derivatives may be of value in treating decreased intestinal motality. - Neurotensin is produced by neurons cells of ileum. Its release is stimulated by fatty acid and it increases ileal blood flow and inhibits gastro intestinal motality. - GIP is produced by K cells in mucosa of duodenum jejunum. Its secretion is stimulated by glucose fatQ in duodenum. It is named so because in large doses it inhibits gastric secretion motality. However in small dose that are seen after meal it does not have significant gastric inhibitory activity. 