<prompt> The drug of choice for obsessive-compulsive disorder isImipramineFluoxetineChlorpromazineBenzodiazepine  <response>: Drug Treatment in obsessive-compulsive disorder: 1. Benzodiazepines e.g. alprazolam, clonazepam have a limited role in controlling anxiety 2. Antidepressants: Clomipramine 75-300 mgday, a nonspecific serotonin reuptake inhibitor SRI, was the first drug used effectively in the treatment of OCD. Fluoxetine 20-80 mgday is a good alternative to clomipramine and often preferred these days for its better side-effect profile. Fluvoxamine 50-200 mgday is marketed as a specific anti-obsessional SSRI drug, whilst paroxetine 20-40 mgday and seraline 50-200 mgday are also effective in some patients. 3. Antipsychotics: These are occasionally used in low doses e.g. haloperidol, risperidone, olanzapine, aripiprazole, pimozide in the treatment of severe, disabling anxiety. 4. Buspirone has also been used beneficially as an adjunct for augmentation of SSRIs, in some patients. Ref: A Sho Textbook of Psychiatry, Niraj Ahuja, 7th Edition, pg. no.98 