<prompt> Which is an ominous sign in case of severe head injuryDevelopment of diabetes insipidusAnisocoriaNew focal deficitDepressed skull fracture  <response>: Head Injury A sudden Enlargement dilatation of one pupil anisocoria is an ominous sign Abnormal posturing decoicate posturing a characteristic positioning of the limbs caused by severe diffuse injury or high ICP is an ominous sign Ref: Harrisons 19th edition Pgno :1774 