<prompt> All are true about pheochromocytoma except:90 are malignant95 occur in the abdomenThey secrete catecholaminesThey arise from sympathetic ganglions  <response>: Only 10 are malignant. They are also called 10 tumors because 10 are bilateral, 10 are extra adrenal, 10 occur in pediatric patients, 10 are familial. One traditional 10 rule that has now been modified peains to familial cases. It is now recognized that as many as 25 of individuals with pheochromocytomas and paragangliomas harbor a germline mutation in one of at least six known genes 