<prompt> Which of the following anti - hypertensives was once used as an antipsychotic?AtenololPropranololClonidineReserpine  <response>: Reserpine is an antihypertensive drug which was used as an antipsychotic. Antipsychotic effect of reserpine is due to depletion of 5 - HT or catecholamine or both.Clonidine is also an antihypertensive. Its uses in psychiatry are - ADHD, opioid withdrawal, Tourettes syndrome and suppression of agitation in PTSD. 