<prompt> Perivascular lymphocytic and microglial nodules are seen inMultiple sclerosisHIV encephalitisBacterial meningitisCMV encephalitis  <response>: HIV encephalitis Chronic inflammatory reaction characterized by widely distributed microglial nodules, often containing macrophage-derived multinucleated giant cells; foci of tissue necrosis . Reactive gliosis are sometimes seen together with these lesions. Microglial nodules found near small blood vessels, show abnormally prominent endothelial cells and perivascular foamy or pigment-laden macrophages. 