<prompt> Common to acyl carrier protein and coenzyme ALocated in mitochondria as well as cytoplasmCarriers of folatePhosphopantotheine is the reactive groupPhosphorylated to tyrosine  <response>: Ans. c Phosphopantotheine is the reactive group. Ref. Harpers Biochemistry 26thpg. 173, 495Pantothenic acid has central role in acyl group metabolism when acting as a functional moiety of coenzyme A or acyl carrier protein ACP.PANTOTHENIC ACID The pantothene functional moiety is formed after combination of pantothenate with cysteine, which provides the -SH prosthetic group of CoA and ACP. CoA takes part in reactions of the citric acid cycle, fatty acid synthesis and oxidation, acetylation, and cholesterol synthesis. ACP participates in fatty acid synthesis. Pantothenic acid is widely distributed in all foods, and deficiency has not been unequivocally reported.Educational point: The fatty acid synthase system is a MULTIENZYME polypeptide complex that incorporates ACP, which takes over the role of CoA and it contains the pantothenic acid in the form of 4-phosphopantetheine. Co-enzyme A CoA is a widely distributed mercaptan containing adenine, ribose, pantothenic acid, and thioethanolamine. 