<prompt> Diagnostic method of choice for leptospirosisMSATMATCold agglutination testLatex agglutination test  <response>: A definitive diagnosis of leptospirosis is based on: - Isolation of the organism from the patient or A positive result in the polymerase chain reaction PCR or Seroconversion or a rise in antibody titer. MAT In cases with strong clinical evidence of infection, a single antibody titer of 1:200-1:800 depending on whether the case occurs in a low- or high-endemic area in the microscopic agglutination test MAT is required. Ref:- Harrisons T.B of internal medicine 19th edition; pg num:- 1144 