<prompt> Resting membrane potential depends mainly on-KNaClHCO3  <response>: Ans. is a i.e., K o This question has been repeated in many exams.o The RMP is principally due to concentration difference chemical difference of K in ECF and ICF. In neurons, the resting membrane potential is usually about -70 mV, which is close to the equilibrium potential for K. Here, it is worth noting that RMP is close to the equilibrium potential of K but the value of RMP is exactly same as equilibrium potential of Cl- It is because other ions also diffuse through membrane, though their effect is very- little.IonEquilibrium potential Isoelectric potential or Nernst potential Na60 mVK-90 mVC1-70 mVRMP in neurons is -70 mV 