<prompt> Coombs positive hemolytic anemia is associated with:TTPPANSLEHUS  <response>: Coombs positive hemolytic anemia is a feature of autoimmune hemolytic anemia and is characteristically seen in Systemic lupus erythematous. Ref: Amit Ghosh, MD 2010, Chapter 24, Rheumatology, In the book, Mayo Clinic Internal Medicine Board Review, 9th Edition, New york, Page 907; Harrisons Principles of Internal Medicine, 16th Edition, Page 612 