<prompt> A 32 year old male patient treated for high blood pressure with thiazides. Which of the following effect can happen in this patient?Hyperkalemic paralysisHypouricemiaHypolipidemiaImpotence  <response>: The incidence of erectile dysfunction is greater with thiazides than with several other antihypeensive agents e.g., beta adrenergic receptor antagonists, Ca2-channel blockers, or angiotensin conveing enzyme inhibitors. Other side effects include, CNS e.g., veigo, headache, paresthesias, xanthopsia, and weakness GI e.g., anorexia, nausea, vomiting, cramping, diarrhea, constipation, cholecystitis, and pancreatitis Hematological e.g., blood dyscrasias Dermatological e.g., photosensitivity and skin rashes Fluid and electrolyte imbalanceS extracellular volume depletion, hypotension, hypokalemia, hyponatremia, hypochloremia, metabolic alkalosis, hypomagnesemia, hypercalcemia, and hyperuricemia Increase in plasma levels of LDL cholesterol, total cholesterol, and total triglycerides Ref: Reilly R.F., Jackson E.K. 2011. Chapter 25. Regulation of Renal Function and Vascular Volume. In L.L. Brunton, B.A. Chabner, B.C. Knollmann Eds, Goodman Gilmans The Pharmacological Basis of Therapeutics, 12e. 