<prompt> Cause of liver cirrhosis in childhood include?Alpha-1 antitrypsin deficiencyCoeliac diseasePhenylketonuriaCows milk intolerance  <response>: Ans. is a i.e., Alpha-1 antitrypsin deficiency Cirrhosis in children o Cirrhosis is a histologically defined condition of the liver characterized by diffuse hepatocyte injury and regeneration. o Causes of cirrhosis in children are ? 1 Post necrotic Viral hepatitis -- HBV, HCV Idiopathic neonatal hepatitis a1-antitrypsin deficiency Autoimmune or drug induced hepatitis Wilson disease Hemochromatosis Tyrosinemia Galactosemia 2 Biliwy Biliary atresia Choledochal cyst Tumor of bile duct Caroli disease Cystic fibrosis Primary sclerosing cholangitis PFIC Paucity of intrahepatic bile ducts 3 Hypersensitivity to drug -- Phenytoin 4 Parasites -- Opisthorchis sinensis, Ascaris, Fasciola. 