<prompt> A 25-years old male patient presents with pigmentation of the lips and oral mucosa and intestinal polyps. His sister also gives the same history. Most probable diagnosis is:Carcinoid tumorMelanomaVillous adenomaPeutz-Jeghers syndrome  <response>: Peutz-Jeghers syndrome - Multiple hamaomatous polyps in S.I - MC pa - Jejunum- Gene- LDB-1 STK-11 - 19p- Hyper melanotic macules over Lips Buccal mucosa - Does not risk of colorectal cancer- risk of S.I. malignancy- risk of- Breast - Thyroid- Pancreas max risk- Endometrial - Seoli cell tumor of testis 