<prompt> A patient of anemia due to chronic inflammation, the positive finding isSerum iron is increasedS. ferritin is decreasedTIBC is decreasedPresence of normal iron in blasts  <response>: Direct quote from Robbins : Hyperacute rejection occurs when preformed antidonor antibodies are present in the circulation of the recipient. Such antibodies may be present:In a recipient who has previously rejected a kidney transplantMultiparous women who develop anti-HLA antibodies against paternal antigens shed from the fetus may have preformed antibodies to grafts taken from their husbands or childrenPrior blood transfusionsIn recipients not previously sensitized to transplantation antigens, exposure to the class I and class II HLA antigens of the donor graft may evoke antibodies. The initial target of these antibodies in rejection seems to be the graft vasculature.Thus, antibody-dependent acute humoral rejection is usually manifested by a vasculitis, sometimes referred to as rejection vasculitis 