<prompt> A 29yr old women comes to clinic because of heat intolerance, excess sweating, thinning of hair. She had family HO of autoimmune disease, she is 8 wks pregnant and has had no other issues during pregnancy. Medical HO includes hypehyroidism. Lab studies are positive for thyroid stimulating immunoglobulin. Wof drug is most appropriate for treatmentMethimazolePropylthiouracilRadioactive iodineOxytocin  <response>: This is a case of Graves disease, which results in thyrotoxicosis. Inhibit hormone synthesis Antithyroid drugs Includes Propylthiouracil, Methimazole, Carbimazole. Mech of action:- Antithyroid drugs bind to the thyroid peroxidase and prevent oxidation of iodide iodotyrosyl residues, thereby; i Inhibit iodination of tyrosine residues in thyroglobulin ii Inhibit coupling of iodotyrosine residues to form T3 and T4. Ref:- kd tripathi; pg num:- 252,253 