<prompt> 6 months old infant with Hb of 6 gm has anaemic features with peripheral blood showing target cells. Family history of similar complaints is Positive. Diagnosis can be best done with which of the following -Hb electrophoresisELISACoombs TestOsmotic fragility  <response>: Ans. is a i.e., Hb Electrophoresis Presence of : 1. Anaemia Hb 6, Target cells, 3. Increase reticulocytes suggests the diagnosis of thalassemia. o Thalassemia is a hemoglobin disorder. Hemoglobin disorders are diagnosed by electrophoresis. o Diagnosis of thalassemia is confirmed by serum electrophoresis. 