<prompt> Which of the following inhibits gastrin secretion?Intrinsic factorEnterogastroneHistamineGastrin  <response>: Enterogastrone is secreted in the ileum. To a minor extend it inhibits gastric and pancreatic secretions. It inhibits the secretion of gastrin. Gastrin: Gastrin is produced by G cells in the antral poion of the gastric mucosa. Functions of gastrin: It increases gastric HCl secretion, decreases insulin secretion, stimulates GI mucosal growth and cause constriction of lower esophageal sphincter. Stimuli that increase gastrin secretion: Luminal: distention, peptides and amino acids Increased vagal discharge GRP Calcium Epinephrine Stimuli that inhibit gastrin secretion Luminal: acid, somatostatin Secretin, GIP, VIP, glucagon, calcitonin Ref: Barrett K.E., Barman S.M., Boitano S., Brooks H.L. 2012. Chapter 25. Overview of Gastrointestinal Function Regulation. In K.E. Barrett, S.M. Barman, S. Boitano, H.L. Brooks Eds, Ganongs Review of Medical Physiology, 24e. 