<prompt> Which liver diseases isare associated with ductopenia?Chronic graft rejectionHepatic sarcoidosisParaneoplastic syndrome related to hodgkins lymphomaAll the above  <response>: Ans. is d i.e., All the above Ductopenia Loss of bile ducts from the portal tracts is referred to as ductopenia. Ductopenia is most commonly seen related to chronic allograft rejection however it can be seen in many disease including drug related injury, primary biliary cirrhosis, primary sclerosing cholangitis, chronic graft- vs-host disease, hepatic sarcoidosis, paraneoplastic syndrome related to Hodgkin disease, and syndromic paucity of bile ducts Alagille syndrome. Ductopenia can be identified by looking for unpaired hepatic arteries or by the aid of immunohistochemical stain CK7. Typically a minimum loss of 30 earlyevolving chronic ductopenic allograft rejection of bile ducts is required for a diagnosis and most cases of ductopenia are defined by loss of at least 50 of bile ducts. Due to sampling issues, at least 10-12 portal tracts must be present to accurately evaluate bile duct loss. 