<prompt> A 61-year-old man presents with a 5-year history of pain in both legs during exercise. He has been treated for diabetes for 8 years. His fasting blood glucose is 280 mgdL. Which of the following best explains the pathogenesis of leg pain in this patient?AtherosclerosisMalignant hypertensionMicroaneurysmsPeripheral neuropathy  <response>: The extent and severity of atherosclerotic lesions in medium-sized and large arteries are increased in patients with long-standing diabetes. Leg pain during walking or exercise, which forces the patient to stop or limp intermittent claudication is typically a complication of atherosclerosis involving the major arteries of the lower extremities. Peripheral neuropathy choice D is a complication of diabetes but is an unlikely cause of claudication. Diabetes does not cause vasculitis choice E.Diagnosis: Atherosclerosis 