<prompt> Lesions of which of the hypothalamic nuclei cause diabetes insipidus?Dorsomedial nucleiSupraoptic and paraventricular nucleiMedian preoptic nucleiVentromedial nuclei  <response>: - Vasopressin, a 9-amino-acid peptide, has both anti-diuretic and vascular pressor activity - It is synthesized in the paraventricular supraoptic nuclei of the hypothalamus. - Deficiency of Vasopressin causes Diabetes insipidus. - DI results in Polyuria polydipsia Satiety center Ventromedial nuclei VMN Reward centre Medial forebrain bundle Circadian rhythm Suprachiasmatic nucleus Oxytocin Paraventricular nucleus 