<prompt> All of the following are true about diffuse gastric cancer according to Laurens classification except:Familialmore common in malesundifferentiatedmore common in the proximal pa  <response>: Lauren Classification System for carcinoma Intestinal Diffuse - Environmental - Gastric atrophy, intestinal metaplasia - Men Women - Increasing incidence with age - Gland formation - Hematogenous spread - Microsatellite instability - APC gene mutations - p53, p16 inactivation - Epidemic - Distal pa of the stomach - Familial - Blood group A - Women Men - Younger age group - Poorly differentiated signet ring cells - Transmural Lymphatic spread - Decreased E-cadherin - p53, p16 inactivation - Endemic - Proximal pa of the stomach 