<prompt> most impoant cell damage in pathogenesis of ARDS isalveolar cell type 1alveolar cell type 2endothelial cell of capillarydue to macrophages  <response>: RESPIRATORY DISTRESS SYNDROME ARDS Acute respiratory distress syndrome ARDS is a life-threatening lung condition that prevents enough oxygen from getting into the blood. Acute respiratory distress syndrome was first described in 1967 by Ashbaugh and colleagues. ARDS is also referred with variety of terms like Stiff Lung Shock lung Wet lung Post traumatic lung Adult respiratory distress syndrome Adult hyaline membrane disease Capillary leak syndrome Congestive atelectasis. ARDS - PATHOGENESIS Insult direct or indirect Activation of inflammatory cells mediators Damage to alveolar capillary membrane Increased permeability of alveolar capillary membrane Influx of protein rich edema fluid and inflammatory cells into air spaces Dysfunction of surfactant ref : robbins 10th ed 