<prompt> Diffuse cutaneous systemic sclerosis is characterised by:Early pulmonary fibrosisRaynauds phenomenonCalcinosis cutisLong term prognosis is better  <response>: Diffuse cutaneous SSc is associated with 1. Progressive skin induration 2. Early pulmonary fibrosis and acute renal involvement. Limited cutaneous SSc have 1. Long-standing Raynauds phenomenon before other manifestations of SSc appear. 2. Skin involvement remains limited to the fingers sclerodactyly A subset of patients with limited systemic sclerosis have a calcinosis cutis, b Raynauds phenomenon, c esophageal dysmotility, d sclerodactyly e telangiectasia Termed CREST syndrome Long term prognosis is poor in diffuse variety than limited systemic sclerosis. Ref: Harrison, E-18, P- 2757. 