<prompt> All of the following statements about Burkitts lymphoma are true, Except:B cell lymphoma8, 14 translocationCan present as an abdominal massRadiotherapy is the treatment of choice  <response>: Answer is D Radiotherapy is the treatment of choice The treatment of choice for Burkitts Lymphoma is chemotherapy and not Radiotherapy. Burkitts lymphoma responds well to sho term high dose chemotherapy. Treatment of Burkitts lymphoma in both children and adults should begin within 48 hours of diagnosis and involves the use of intensive combination chemotherapy regimens - Harrisons Burkitts Lymphoma is a B cell lymphoma Burkitts Lymphoma are tumors of mature B cells - Robbins 7th677 t 8;14 translocation is the most common translocation in Burkitts Lymphoma Burkitts lymphomas are associated with translocation of the c-MYC gene on chromosome 8. Translocation t 8; 14 t 8; 22 t 2; 8 Burkitts Lymphoma may present with an abdominal mass Most Burkitts Lymphoma presents at extranodal sites but may present with lymphadenopathy Extranodal sites of involvement include the mandible and abdominal viscera Burkitts Lymphomas may present with peripheral lymphadenopathy or an intraabdominal mass - Harrison CNS involvement is frequent The disease is rapidly progressive and has a propensity to metastasize to CNS, prophylactic therapy to CNS is therefore mandatory. Burkitts Lymphoma is the most rapidly progressive human tumor 