<prompt> A 55 year old lady presenting to out patient depament with postmenopausal bleeding for 3 months has a 1 x 1 cm nodule on the anterior lip of cervix. Which of the following is the most appropriate investigation to be done subsequently in this care?Pap smearPunch biopsyColposcopyEndocervical curettage  <response>: Most appropriate investigation which can be done in the OPD in this patient who has a visible 1 x 1 cm nodule on the anterior lip of cervix is puch biopsy. For non-visible lesions coloposcopy allows accurate delineation of suspicious areas for tissue biopsy. Ref: Shaws Textbook of Gynaecology, 13th Edition, Page 384 