<prompt> Karyotyping can be used to diagnose which of the following disease?Klinefelters syndromeMultiple myelomaNiemann-Pick diseasePemphigus  <response>: The only disease listed that is related to an abnormal number of chromosomes is Klinefelters syndrome. This disease is characterized by two or more X chromosomes and one or more Y chromosome. Typically, those affected have 47 chromosomes with a karyotype of XXY. 