<prompt> Carbimazole as compared to propylthiouracil:Is less potentIs shoer actingDoes not produce an active metaboliteDoes not inhibit peripheral conversion of T4 to T3  <response>: Ref: KDT 6e p250 Carbimazole Propylthiouracil Produces an active metabolite, methimazole No active metabolite Less plasma protein binding PPB More PPB Crosses placenta Does not cross placenta More potent Less potent Does not inhibit 5-deiodinase Inhibits 5-deiodinase 