<prompt> The enzyme activated with low Insulin : Glucagon ratio is?Glucose 6-phosphate dehydrogenaseGlucokinasePyruvate kinaseGlucose - 6 - Phosphatase  <response>: Insulin is released in Fed state. Low Insulin:Glucagon ratio means Catabolic state As low insulin means Fasting state or catabolic state Insulin activates all anabolic enzymes with exception that it also promotes catabolic pathways glycolysis and link reaction. Enzmes Pathway Fed state activity Fasting state activity Glucokinase Glycolysis Increased Low Pyruvate Kinase Glycolysis Increased Low Glucose 6-phosphate dehydrogenase HMP Increased Low Glucose 6 Phosphatase Gluconeogenesis Low Increased 