<prompt> Which cytokine activate macrophages ?IL-8IFN-yPAFLeukotriene B4  <response>: Ans. is b i.e., IFN-T Activated macrophages o Recent studies show that there are two types of activated macrophages : ? 1. Classically activated macrophages M2 These are activated by microbial products and cytokines like IFNI! o These cells release lysosomal enzymes, NO, IL-1, and IL-12. o These cells are involved in microbicidal activities and pathogenic inflammation. 2. Alternatively activated macrophages M2. o These cells are activated by microbial products and cytokines like IL-4, IL-5. o These cells release IL-10, TGF-P. o These cells are involved in anti-inflamatory actions and wound repair. 