<prompt> A typical example of an immunologically mediated collagen, connective tissue disorder:PemphigusBullous pemphigusLupus erythematousLichen planus  <response>: Systemic Lupus Erythematosus is a multisystem autoimmune disease characterised by autoantibodies, immune complex formation and immune dysregulation resulting in damage to kidney, skin, blood vessels, CNS. 