<prompt> Function of infliximab used in Crohn;s isInhibit TNF-aInhibit IL-2EGFR inhibitorInhibit VEGF  <response>: Infliximab, a chimeric IgG1 antibody against TNF-a, is approved for treatment of moderately to severely active UC.Infliximab is also effective in CD patients with refractory perianal and enterocutaneous fistulasAdalimumab and ceolizumab, golimumab are other Anti-TNF therapies approved for IBDInfliximab is also approved for psoriasis, psoriatic ahritis, ankylosing spondylitis, and rheumatoid ahritisRef: Harrison 19e pg: 1961 