<prompt> HPV oncogene expression isE1E2E1E3E3E5E6E7  <response>: The oncogenic potential of HPV can be related to production of two early viral genes E6E7 Together they interact with variety of growth regulating proteins encoded by protooncogene and tumour suppressor genes E6- binds to and mediate the degradation of p53 E7-binds to Rb protein and release E2F transcription factor,also inactivates the CDKIs Robbins basic pathology 9th edition chapter 5 pageno. 202 