<prompt> The enzyme deficient in Lysch Nyhan syndrome is:-Adenosine DeaminasePRPP synthetaseHGPaseXanthine oxidase  <response>: HGPase Hypoxanthine guanine phosphoribosyl transferase deficiency: Causes Lesch-Nyhan syndrome. synthesis of purine nucleotides utilization of purines hypoxanthine and guanine by salvage pathway-accumulation of PRPP Neurotoxic component- Self mutilation Defect in salvage pathway- IMP and CMP - impairment feedback regulation of their production 