<prompt> In oesophageal ca which Neoadjuvant chemotherapy is used :CisplatinCyclophosphamideDoxorubicinMethotrexate  <response>: Ans. is a ie Cisplatin Sabiston writes- Since its introduction in 1980, cisplatin has emerged as the cornerstone of combination therapy in esophageal cancer. As a single agent, it has a response rate of 25 to 30. Given in combination with 5- fluorouracil, a response rate of 50 may be achieved, and this is an established chemotherapeutic regimen for esophageal cancer. 