<prompt> In Chronic Viral Hepatitis -Hepatitis A virus infection is a common cause in childrenMorphological classification into Chronic Active Hepatitis and Chronic Persistent Hepatitis are impoantFatty change is pathognomic of Hepatitis C virus infectionGrading refers to the extent of necrosis and inflammations  <response>: Ans. is d i.e., Grading refers to the extent of necrosis and inflammationClassification of hepatitis o In the new classification system of Hepatitis, Grading refers to the assessment of necroinflammatory activity.o Chronic hepatitis represents a series of liver disorders of varying causes and severity in which hepatic inflammation and necrosis continue for at least 6 months.o Earlier chronic hepatitis was categorized into three types depending upon histopathological features. These area Chronic persistent hepatitisb Chronic lobular hepatitisc Chronic active hepatitiso Now, this categorization has been replaced by more informative classification based upon a combination of clinical serological and histological variables.o Now the classification is based upona Its causeb Its histologic activity or gradec Its degree of progression or stagea Classification by causeIn this the hepatitis is classified according to the cause - such as viral hepatitis, autoimmune hepatitis, drug - associated hepatitis.b Classification by Grade -o This classification is based upon assessment of necroinflammatory activity.o An assessment of following histological features is made on liver biopsy -Peripoal necrosis Piecemeal necrosis Bridging necrosis Poal inflammationc Classification by stageThis classification is based upon the degree of fibrosis.It reflects the levels of progression of disease.Staging is based upon the degree of fibrosis as follows0 No fibrosis1 Mild fibrosis limited to poal tract2 Moderate fibrosis Poal and peripoal fibrosis3 Severe fibrosis including bridging fibrosis4 Cirrhosis 