<prompt> Dantrolene sodium reduces skeletal muscle tone by:Reducing acetylcholine release from motor nerve endingsSuppressing spinal polysynaptic reflexesInhibiting the generation of muscle action potentialReducing Ca2 release from sarcoplasmic reticulum in the muscle fibre  <response>: Dantrolene is the drug of choice for the treatment of malignant hypehermia and neuroleptic malignant syndrome. It acts as an antagonist of Ryanodine receptors present on smooth endoplasmic reticulum. It inhibits the release of Ca2 from sarcoplasmic reticulum in the muscle fibre. 