<prompt> Dukes stage C2 refers to carcinoma -Bladder penetrating the extravesical fatBladder with metastasis to internal iliac lymph nodesWith histological features of 75 anaplastic cellsRectum with metastasis to inferior mesentric lymph nodes  <response>: Dukes staging is used for colorectal cancer.In Dukes C stage, there is involvement of regional lymphnodes.Dukes staging has been explained earlier. 