<prompt> A 26 year old patient presents with suspected pneumococcal meningitis. CSF culture is sent for antibiotic sensitivity. Which empirical antibiotic should be given till culture sensitivity result come?Penicillin GCeftriaxone metronidazoleDoxycyclineCefotaxime vancomycin  <response>: Ans. D Cefotaxime vancomycinRef: Harrison 18e p3414Antibiotics Used in Empirical Therapy of Bacterial Meningitis and Focal CNS InfectionsIndicationAntibioticInfants 3 monthsAmpicillin Cefotaxime3 months to 55 yearsCefotaxime Ceftriaxone VancomycinAdults 55 yearsAmpicillin Cefotaxime Ceftriaxone VancomycinHospital-acquired meningitis post-traumatic or post-neurosurgery meningitis, neutropenic patients, or patients with impaired cell-mediated immunityVancomycin Cefepime 