<prompt> Colonic metastases are related with:Preoperative CEA levelDepth of invasionSize of tumorCircumferential involvement  <response>: Ans. b Depth of invasionRef: Schwartz 9th edition, Page 1046; Shackelford 7th edition, Page 2133 Colonic metastasis to liver is related to -- depth of invasion T stage CRC prognosis depends on the stage of the disease Especially in stage on the lymph node status Tumor size and duration has no effect on prognosis. 