<prompt> The neo-adjuvant chemotherapy indicated in oesophageal carcinomaCisplatinDoxorubicinMitomycin C5-FU-Leucovarin  <response>: Treatment of CA esophagus High-grade dysplasia Tis or T1a Endoscopic mucosal resection Localised advanced cancer T1: Vagal sparing or transhiatal or minimal invasive esophagectomy with limited LN dissection T2 and T3: Neoadjuvant Chemoradiation surgery Cervical SCC or Non-ideal candidate for resection : Definitive chemoradiation Locally advanced cancer Chemoradiation - surgical resection in T4a Metastatic disease Definitive chemoradiation for involved distant LN or metastatic disease Malignant TEF Coated SEMS Self expanding metallic stents Chemotherapy regimen : Epirubicin Cisplatin 5-FU Ref: Shackelford 7th edition Pgno : 438-448 