<prompt> Chediak_higashi syndrome is due to defect inOpsonisationChemotaxisLADExtracellular microbacterial killing  <response>: Ref Walter and Israel 7e p150 Chediak Higashi syndrome is an autosomal ressive Condition in which polymorphs exhibit defective random movements , defective chemotaxis and impairee degranulation on phagocytosis paicles 