<prompt> A patient develops an ovarian mass that is picked up on pelvic examination. Resection of the mass demonstrates a lymphoma composed of small lymphocytes with interspersed macrophages surrounded by clear spaces. This lesion would be most likely to be associated with which of the following?abl-bcr hybridbcl-2 activationc-myc activationt 9,22  <response>: The condition is Burkitt lymphoma the major clue is the starry sky pattern described, which occurs as a jaw lesion in epidemic form in Africa associated with Epstein-Barr virus and in a sporadic form that usually involves the pelvic or abdominal organs. Burkitt lymphoma is associated with c-myc activation due to a t 8,14 translocation that places the c-myc-containing segment of chromosome 8 near an actively transcribed gene for immunoglobulin heavy chains. t 9,22 and abl-bcr hybrid are associated with chronic myeloid leukemia CML. t 14, 18 and bcl-2 are associated with follicular lymphomas, not Burkitt lymphoma. 