<prompt> Volatile agent which causes most renal toxicity isEtherIsofluraneMethoxyfluraneSevoflurane  <response>: Methoxyflurane is most metabolized and produces more than 80 micromollitre of flouride in blood. The amount of fluoride ions produced: Methoxyflurane: 50uM Sevoflurane: 20-30 uM Enflurane: 20uM Isoflurane and desflurane: 5uM 