<prompt> Buergers Disease isAlso known as Thromboangitis ObliteransSegmental inflammatory diseaseAffects small and medium arteries in upper and lower extremitiesAll of the above  <response>: BUERGERS DISEASE THROMBOANGITIS OBLITERANS Segmental inflammatory disease, affecting small and medium sized arteries in upper and lower extremities. Inflammatory process involves neighboring veins and nerves. Definite relationship with smoking.Histopathology Sharply segmental acute and chronic vasculitis of small and medium vessels with thrombosis of lumen, which may undergo organization and recanalization. Thrombus contains microabsecessInflammatory process extends to involve neighboring veins and nerves.With time, all three structures artery, vein and nerve become incased in fibrous tissue.Clinical Features RIM Characterized by triad of intermittent claudication, Raynauds phenomenon and migratory superficial vein thrombophlebitis.Typically seen in young 40 years, male smokers. 