<prompt> Which of the following statements about clinical uses of the aminoglycosides is FALSE?Owing to their polar nature,aminoglycosides are not absorbed following oral adminissstrationAminoglycosides are often used in combination with cephalosporibns in the empirical treatment of life-threatenting bacterial infectionsThe spectrum of antimicrobial activity of aminoglycosides includes Bacteroides fragilisGentamicin is used with ampicillin for synergistic effects in the treatment of enterococcalendocarditis  <response>: Ref:KDT 6e p719, 720; Katzung 10e p758 These are bactericidal inhibitors of protein synthesis. Due to formation of ionic nolecules in GIT, these are ineffective orally. Combination of aminoglycosides with penicillins is synergistic and is used for pseudomonas and enterococcal infections. 