<prompt> Highest trans-membrane voltage difference exists for which of the following cells?Smooth muscle cellHair cellPurkinje fiberSkeletal muscle fiber  <response>: When membrane potential is said to be - 70 mV for nerve, it is a relative term, with exterior taken to be zero. The transmembrane voltage difference is thus 70 mV in this case. hair cells are surrounded by endolymph, the fluid with high concentration of K. The high K causes a potential of 80 mV in endolymph - the endocochlear potential, surrounding the hair cells. Thus, a total of 150 mV potential difference exists across hair cell membrane 80 - , highest for any cell in the body. 