<prompt> All of the following are true regarding Hyper IgE syndrome, except:Autosomal dominantKyphoscoliosisRecurrent cutaneous abscessesLow serum IgG, IgA and IgM levels  <response>: Hyper IgE syndrome Jobs syndrome Autosomal dominant inhibitory mutations in signal transducer and activator of transcription 3 STAT3 lead to inhibition of normal STAT signaling Patients have characteristic facies:- Broad nose Kyphoscoliosis Osteoporosis Eczema Abnormal chemotaxis is a variable feature Recurrent sinopulmonary and cutaneous infections cold abscesses Serum IgE level is significantly elevated whereas IgM, IgG and IgA level are normal In vivo assessment of inflammation is possible with a Rebuck skin window test or an in vivo skin blister assay, which measures the ability of leukocytes and inflammatory mediators to accumulate locally in the skin. In vitro tests of phagocyte aggregation, adherence, chemotaxis, phagocytosis, degranulation, and microbicidal activity for S. aureus are used for laboratory diagnosis 