<prompt> Inheritance of Familial Hypercholesterolemia is?Autosomal dominantAutosomal recessiveX Linked dominantX Linked recessive  <response>: ANSWER: A Autosomal dominantREF: Lehninger Principles of Biochemistry 4th edition page 827, stylecolor: rgba20, 20, 20, 1; font-family: Times New Roman, Times, serif pubmedhealthPMH0001429In familial hypercholesterolemia, a human genetic disorder, blood levels of cholesterol are extremely high and severe atherosclerosis develops in childhood. These individuals have a defective LDL receptor and lack receptor-mediated uptake of cholesterol carried by LDL. Consequently, cholesterol is not cleared from the blood; it accumulates and contributes to the formation of atherosclerotic plaques.Familial hypercholesterolemia is a genetic disorder caused by a defect on chromosome 19. The condition is typically passed down through families in an autosomal dominant manner. The most common genetic defects in FH are LDLR mutations prevalence 1 in 500, depending on the population, ApoB mutations prevalence 1 in 1000, PCSK9 mutations less than 1 in 2500 and LDLRAP1 