<prompt> Splenectomy is most useful in :ThrombocytopeniaHereditary spherocytosisH.S. purpuraSickle cell anemia  <response>: Answer is B Hereditary spherocytosis Splenectomy is curative in hereditary spherocytosis. Splenectomy is carried out in all symptomatic patients Q because of the potential for gall stones and stones and episodes of bone marrow hyperplasia or hemolytic crisis Q It reliably corrects the anemia and RBC survival often becomes normal or nearly so. The operative risk is low. Remember Splenectomy is not carried out in young children e preferably postponed until age 4 in order to minimize the risk of severe infections Q with gram positive encapsulated organisms. 