<prompt> Based on Epidemiological studies, which of the following has been found to be most protective against Carcinoma Colon :High fiber dietLow fat dietLow selenium dietLow protein diet  <response>: Answer is A High fiber diet: Epidemiologic, case control and animal studies suggest that dietary fibers are protective against the development of colon cancer Fat is primarily related as a promoting agent such that high fat in diet is believed to promote carcinogenesis. Low Fat has not been shown to have a protective role in carcinogenesis although it may reduce the incidence of colonic carcinoma indirectly by reducing a promoting effect. Low selenium is possibly related as a promoting agent Low Protein has not been mentioned in relation to carcinogenesis in the colon. 