<prompt> Regarding PCOS and hyperinsulinaemia true statement is :Hyperinsulinaemia is observed in about 40 to 80 of women with PCOSHyperinsulinaemia stimulates hepatic synthesis of SHBGMetformin causes hypoglycaemia in normoglycaemic womenMetformin has many other health benefits  <response>: In PCOS Hyperinsulinemia is seen in 50-70 cases of PCOS Insulin induces LH to cause thecal hyperplasia and secrete androgens Hyperandrogenism lowers the level of hepatic sex hormone binding globulin Metformin treats the root causes, rectifies endocrine and metabolic function, improves feility rate, used as insulin sensitiser It reduces insulin level, delays glucose absorption, liver production of glucose and improves peripheral resistance Metformin do not cause hypoglycemia in a normoglycemic women Ref: SHAWS TEXTBOOK OFGYNECOLOGY;15 TH EDITION; PG NO: 370 