<prompt> Autosplenectomy occurs in:ThalassemiaSickle cell anemiaHbH diseaseHydrops fetalis  <response>: b. Sickle cell anemiaRef: Nelsons 20e p 2336, Ghai 8e p 345Patients of sickle cell anemia may undergo auto-splenectomyQ due to multiple infarcts in splenic artery, that causes spleen to be reduced to fibrous tissue splenic atrophy spleen may become non-palpable. 