<prompt> A 25-year-old man presents to rheumatologist with complaints of joint pain involving large joints of legs which exacerbates frequently accompanied by diarrhea. Which of the following gastrointestinal diseases is most likely to be implicated as the cause of the patients joint problems?Amebic colitisChronic appendicitisDiveiculosisUlcerative colitis  <response>: - Most frequent GIT disorder associated with sacroiliitis related to HLA-B27 or lower limb ahritis is chronic inflammatory bowel diseases like ulcerative colitis Crohns disease. - Other GI diseases associated with ahropathy are Whipples disease, Behcets syndrome, and celiac disease. 