<prompt> The most common systemic association of scleritis is-Ehlers - Danlos syndromeDisseminated systemic sclerosisRheumatiod ahritisGiant cell aeritis  <response>: Scleritis refers to a chronic inflammation of the scleraproper. It is a comparatively serious disease whichmay cause visual impairment and even loss of theeye if treated inadequately. Autoimmune collagen disorders, especiallyrheumatoid ahritis, is the most commonassociation. Overall about 5 cases of scleritisare associated with some connective tissuedisease. About 0.5 percent of patients 1 in 200suffering from seropositive rheumatoid ahritisdevelop scleritis. Other associated collagendisorders are Wegeners granulomatosis,polyaeritis nodosa PAN, systemic lupuserythematosus SLE and ankylosing spondylitis. REF:Comprehensive ophthalmology,AK Khurana,4th edition,pg no.129. 