<prompt> Wiskott Aldrich syndrome true is -Raised IgEReduced IgMReduced IgACD4 and CD8 defect  <response>: In Wiskott-Aldrich syndrome serum IgM level is low but IgG IgA levels are normal or elevated. Isohemagglutinins are absent in the serum. The humaral defect appears to be specific inabilityvto respond to polysaccharide antigens. Ref: Ananthanarayan Panikers textbook of microbiology 9th edition pg.no. : 174 