<prompt> After an initial pregnancy resulted in a spontaneous loss in the first trimester, your patient is concerned about the possibility of this recurring. An appropriate answer would be that the chance of recurrenceDepends on the genetic makeup of the prior abortusIs no different than it was prior to the miscarriageIs increased to approximately 50Is increased most likely to greater than 50  <response>: An initial spontaneous abortion, irrespective of the karyotype or sex of the child, does not change the risk of recurrence in a future pregnancy. The rate is commonly quoted as 15 of all known pregnancies. 