<prompt> Findings in familial hypercholesterolemia: PGI Dec 2007HDLLDLtotal cholesterolHDL  <response>: Ans.: C Total cholesterol Familial hypercholesterolemia is a autosomal codominant disorder characterized by elevated LDL - C with normal triglyceride,, tendon xanthomas and premature atherosclerosis- Harrison 17th1720 Type 11 hyperlipoproteinemias is also known as familial hypercholesterolemiaChaterjea Shinde 7th424Table Harrison: Frederickson Classification of HyperlipoproteinemiasPhenotypeIIIaIIbIIIVVLipoprotein, elevatedChylomicronsLDLLDL and VLDLChylomicron and VLDL remnantsVLDLChylomicrons and VLDLTriglyceridesQ-- to Cholesterol to to to to to LDL-cholesterolHDL-cholesterolPlasma appearanceLactescentClearClearTurbidTurbidLactescentXanthomasEruptiveTendon, tuberousNonePalmar, tuberoeruptiveNoneEruptivePancreatitis0000Coronary atherosclerosis0--Peripheral atherosclerosis0-_Molecular defectsLPL and apoC-IILDL receptor, ApoB- 100, PCSK9, ARH, ABCG5 and ABCG8UnknownApoEApoA-V and UnknownApoA-V and UnknownGenetic nomenclatureFCSFH, FDB, ADH, ARH. sitosteroiemiaFCHLFDBLFHTGFHTGNote: LPLr lipoprotein lipase; apo, apolipoprotein; FCS, familial chylomicronemia syndrome; FH. familial hypercholesterolemia; FD8, familial defective apoB; ARM, autosomal recessive hypercholesterolemia; ADH, autosomal dominant hypercholesterolemia; FCHL, familial combined hyperlipidemia; FDBL, familial dysbetalipoproteinemia; FHTG, familial hypertriglyceridemia 