<prompt> A male infant presented with distension of abdomen shortly after birth with passing of less meconium. Subsequently a full-thickness biopsy of the rectum was performed. The rectal biopsy is likely to show:Fibrosis of submucosaLack of ganglion cellsThickened muscularis propriaHyalinization of the muscular coat  <response>: b. Lack of ganglion cellsRef: Nelsons 20e p 1894-1897, Ghai 8e p 285-286Whenever neonate presents with delayed passage of stool, Hirschsprungs disease should be suspected. 