<prompt> Patient diagnosed with HIV and Tuberculosis. How to sta ATT and c-A.R.TSta ATT firstSta cA firstSta both simultaneouslySta cA only  <response>: Ans. is a i.e., Sta ATT first In a case when HIV and TB are diagnosed together ATT should be staed first. ATT staed first, because of IRIS Immune Reconstitution Inflammatory syndrome. If A staed first, it may improve CD4 cells at first, but later a previously acquired infection TB, Herpes, responds with an overshelming inflammatory response that paradoxically makes the symptom of infection worse. Therefore, staing of ATT-2 weeks before A, have shown to decrease the incidence of IRIS. 