<prompt> Massive splenomegaly is not a feature of-Acute lymphocytic leukemiaChronic myeloid leukemiaMyelofibrosis with myeloid metaplasiaHairy cell leukemia  <response>: Acute lymphoblastic leukemia, also known as acute lymphocytic leukemia or acute lymphoid leukemia ALL, is an acute form of leukemia, or cancer of the white blood cells, characterized by the overproduction and accumulation of cancerous, immature white blood cells, known as lymphoblasts. In persons with ALL, lymphoblasts are overproduced in the bone marrow and continuously multiply, causing damage and death by inhibiting the production of normal cells such as red and white blood cells and platelets in the bone marrow and by spreading infiltrating to other organs. ALL is most common in childhood, with a peak incidence at 2-5 years of age and another peak in old age.The most common causes of splenomegaly in developed countries are infectious mononucleosis, splenic infiltration with cancer cells from a hematological malignancy and poal hypeension most commonly secondary to liver disease, and Sarcoidosis. Splenomegaly may also come from bacterial infections, such as syphilis or an infection of the heas inner lining endocarditisThe causes of massive splenomegaly spleen 1000 g are fewer, and include: visceral leishmaniasis kala-azar chronic myelogenous leukemia myelofibrosis malaria splenic marginal zone lymphoma 