<prompt> Which one of the following is an absolute contraindication to the use of thrombolytic agent in the setting of an acute anterior wall myocardial infarction-History of CVA with hemiparesis one month agoDiabetic retinopathyPatients age more than 70 yearsPatients is on warfarin for A.F with INR ration 1:8  <response>: Ref: R. Alagappan Manual for Medicine 4th Edition pg no:188-189 Contraindications for Thrombolytic Therapy Absolute contraindications: Active bleeding Defective haemostasis Recent major trauma Surgical procedures 10 days Invasive procedures 10 days Neurosurgical procedure 2 months GIgenito-urinary bleeding 6 months StrokeTIA 12 months Prolonged CPR 10 minutes HO CNS tumour, aneurysm, AV malformation Active peptic ulcer Aoic dissection Acute pericarditis Active inflammatory bowel disease Active cavitary lung disease Pregnancy Relative contraindications: Systolic BP 180 mm Hg Diastolic BP 110 mm Hg Bacterial endocarditis Haemorrhagic diabetic retinopathy HO intraocular bleeding Chronic warfarin therapy Severe renal or liver disease Severe menstrual bleeding 