<prompt> All of the following are contraindications for breast conserving surgery exceptTumours more than 4cm in sizeMulticentricityCentrally located tumourPrior neoadjuvant chemotherapy  <response>: Answer- D. Prior neoadjuvant chemotherapyInvolves resection of the primary breast cancer with a margin of normal-appearing breast tissue, adjuvant radiation therapy with or without assessment of axillary lymph node status. 