<prompt> All of the following statements about Creutzfcldt-Jakob disease are true, EXCEPTIt is a neurodegenerative diseaseIt is caused by infectious proteinsMyoclonus is rarely seenBrain biopsy is specific for diagnosis  <response>: C Myoclonus is rarely seen Creutzfeldt-Jakob disease is a neurodegenerative disease caused by Prions Myoclonus is seen in 90 of patients with Creutzfeldt - Jakob disease. Prions are infectious proteinaceous material devoid of detectable amount of nucleic acids. Characteristics of diseases caused by Prions - Diseases are confined to central nervous system Basic pathology is - Neurodegeneration - Spongiform encephalopathy Presence of Amyloid plaques in brain Hosts shows no inflammatory response Disease is almost always fatal Clinical features Symptoms: Usually presents in middle ages Rapidly progressive dementia Myoclonic fasciculations seen in 90 Ataxia Somnolence Characteristic EEC pattern - Paroxysms with high voltage and slow waves 