<prompt> Diarrhoea with acantholysis in urineWhipples diseaseCeliac sprueAbetalipoproteinemiaUlcerative colitis  <response>: Harrisons principles of internal medicine 17th edition. Steatorrheal cause of chronic diarrhea is a mucosal malabsorption caused by celiac disease,whipples disease and abetalipoproteinemia. Abetalipoproteinemia is a rare defect is a defect of chylomicron formation and fat malabsorption in children associated with acantholytic erythrocytes,,ataxia and retinitis pigmentosa. 