<prompt> Which one is the best prognostic factor for ALL?HyperploidyOrgnomegalyTLC more than 50,000mLResponse to treatment  <response>: d. Response to treatmentRef: Nelsons 20e p 2437, Ghai 8e p 599Discussing options one by one:a. HyperploidyIntermediate prognosis; can be considered goodb. OrganomegalyL. Node, liver, spleen enlargement, Testicular enlargement - poor prognosisc. TLC 50,000mLPoor prognosis; TLC 10,000mL has good prognosisd. Response to treatmentEarly response to treatment is a good prognostic factor for ALL 