<prompt> Nutrient and oxygen reach the chondrocytes across perichondrium byCapillariesDiffusionAlong neuronsActive transpo  <response>: an impoant fact about cailage matrix is that it is avascular, i.e. not supplied by capillariestherefore, chondrocytes within the matrix must receive nutrients and oxygen by diffusion from vessels that lie outside the cailagethis long-distance diffusion is possible because of the large volume of water trapped within the matrixRefer: Manish Kumar Varshneys Essential Ohopedics Principles Practice, 1st edition, pg no. 7, 347 