<prompt> Antigen-antibody binding occurs atCenterInside moleculeAnywhere in structureSurface  <response>: General features of the antigen-antibody reactionThe reaction is specific, an antigen combines with only its homologous antibody and vice versa, the specificity however is not absolute.Antigen-Antibody reaction requires the presence of electrolytes at a specific pH and temperatureBonds involved in Antigen-Antibody reaction are - Van der Waals bond, Ionic bonds, and Hydrogen bondingCovalent bonds are not involved There is no denaturation of the antigen or antibody during the reactionEntire molecule of the antigen and antibody reactsThe combination occurs at the surface. Therefore it is surface antigens that are immunologically relevantThe combination is firm and reversibleBoth antigen and antibody participate in the formation of agglutinates or precipitates. 