<prompt> Antegrade peristalsis is due toSerotoninAchSubstance PVIP  <response>: Peristalsis can be defined as a motor pattern of the gut organ musculature that can propel content into the anal antegrade peristalsis or oral retrograde peristalsis direction Impulses travelling orad activate ascending contraction Neurotransmitters here are acetylcholine, substance P, and neurokinin A. Impulses travelling caudad activate descending relaxation Neurotransmitters here are VIP, NO, and PACAP pituitary adenylyl cyclase activating polypeptide. Ref:- Physiology of the Gastrointestinal Tract Sixth Edition; pg num:- 368 