<prompt> A 42 year old male with a past history of a manic episode presents with an illness of 1 month duration characterized by depressed mood, anhedonia and profound psychomotor retardation. The most appropriate management strategy is prescribing a combination of:Antipsychotics and antidepressantsAntidepressants and mood stabilizersAntipsychotics and mood stabilizersAntidepressants and benzodiazepines  <response>: B i.e. Antidepressant mood stabilizersThe patient is suffering from bipolar mood disorder as there is past history of manic episode currently is suffering from depressive episode as shown by depressed mood, anhedonia i.e. not attaining pleasure nihilism, psycho-motor retardation. Treatment strategy Antidepressant Mood stabilizerLi, valproate, carbamazepine, oxcarbazipine is treatment of choice.Antipsychotics are used in:Delusional depressionAcute manic episode when mood stabilizers are not effective or indicated: IVIM as anemergency treatment of mania; along with mood stabilizers for the first few weeks before their effect appears. 