<prompt> Xeroderma pigmentosum is characterized byAutosomaL dominant inheritanceInability to repair sunlight induced damage to DNAIrregular accumulation of melanin in the basal cell layerAcanthosis of epithelium with elongation of rete ridges  <response>: Xeroderma pigmentosum is a genetically determined disorder, in which defective DNA repair mechanisms lead to chronic UV damage and subsequent development of different sun related skin tumors, including melanoma, in sun exposed areas. 