<prompt> X-ray skull characteristically shows Hair on endappearance in which of the following disease?Stills diseaseScurvyNeuroblastomaCirrhosis of liver  <response>: The hair on end sign refers to a radiographic appearance on skull which results from a periosteal reaction manifesting as perpendicular trabeculations interspersed by radiolucent marrow hyperplasia along the skull vault. Mnemonic: H.I.N.E.S.T Hereditary spherocytosis Iron deficiency Anemia Neuroblastoma Enzyme deficiency e.g. G-6-P deficiency causing Hemolytic Anemia Sickle cell disease Thalassemia major 