<prompt> Proton pump inhibitors are most effective when they are given:After mealsShortly before mealsAlong with H2 blockersDuring prolonged fasting periods  <response>: Ans. B Shortly before mealsRef: KDT 8the p700Proton pump inhibitors are used just before meals. Food stimulates the secretion of gastric acid that will be reduced by PPIs if these are given just before meals. 