<prompt> All are true about Duchene Muscular Dystrophy Except:-Swollen Calf is presentPatient uses his own body to climb up.Distal muscle weakness is seenCardiomyopathy and congestive hea failure are seen  <response>: Explanation Proximal muscle weakness is seen Defect in Dystrophin gene Largest gene in human Swollen calf - Pseudohyperophy of calf Fibrous fatty deposit Gowers sign: -Patient uses his own body to climb up as there is proximal muscle weakness. X-linked recessive Xp 21 Average life span is 26 years Boys- more common Definitive diagnosis is by muscle biopsy and genetic studies. 