<prompt> Investigation of choice in case of a pt. with episodic hypeension, headache and thyroid nodule ?Urinary HIAAUrinary catecholomine and aspiration of noduleThyroid function test onlyUrinary basic amino acid metabolite  <response>: Ans is B ie Urinary catecholamines and aspiration of nodule This pt is having MEN type II syndrome which is characterized by Pheochromocytoma and Medullary carcinoma of thyroid MCT Urinary catecholamines are increased in pheochromocytoma Aspiration of nodule will show amyloid material seen in MCT 