<prompt> The mitochondrial enzyme involved in the metabolism of clopidogrel and proton pump inhibitors is:CYP3A4CYP2D6CYP 2C19CYP 2C9  <response>: 50 of drugs are metabolized bycyp3a4 20-30 by cyp2d6 cyp2c19-omeprazole, clopidogrel, diazepam, citalopram, etc KD Tripathi 8th ed 