<prompt> Least common site for vegetation isAerial stenosisMitral stenosisAerial septal defectMitral regurgitation  <response>: Ref Harrison 19 th ed pg 820 Infection most commonly involves hea valves but may also occur on the low-pressure side of a ventricular septal defect, on mural endocardium damaged by aberrant jets of blood or foreign bodies, or on intracardiac devices themselves. The analogous process involving aeriovenous shunts, aerio-aerial shunts patent ductus aeriosus, or a coarctation of the aoa is called infective endaeritis. 