<prompt> A 25-year-old woman complains of low-grade fever, fatigue, and persistent rash over her nose and upper chest. She also notes pain in her knees and elbows. A skin biopsy shows dermal inflammation and granular deposits of IgG and C3 complement along the basement membrane at the epidermaldermal junction. Urinalysis reveals microscopic hematuria and proteinuria. The ANA is positive. The development of thromboembolic complications e.g., deep venous thrombosis in this patient is commonly associated with elevated serum levels of antibodies to which of the following antigens?ABO blood group antigensClass II HLA moleculesClotting factorsPhospholipids  <response>: 13rd of patients with SLE possess elevated concentrations of anti-phospholipid antibodies. It predisposes these patients to thromboembolic complications stroke, pulmonary embolism, deep venous thrombosis, and poal vein thrombosis. The clinical course of SLE is highly variable and typically exhibits exacerbations and remissions. The overall 10-year survival rate approaches 90Because of early detection management. -Antibodies against clotting factors choice C or fibrinolytic enzymes choice D are not involved in the clotting tendency associated with SLE. Diagnosis: Systemic lupus erythematosus 