<prompt> Bleeding disorders with T APTT and 1st PT:Factor 13 deficiencySevere liver diseaseImmune thrombocytopenic purpuraAll  <response>: Ans. is b i.e., Severe liver disease o Prothrombin time assesses factor V, VII, X II ; all of which are synthesized in liver. o PTT assess measures activity of factor V, VIII, IX, X, XI, XII II some of which II, VIII, VII, X, V are synthesized in liver. So, in liver diseases both aPTT as well as PT are increased. In immune thrombocytopenia, there is increased BT due to platelet defect. 