<prompt> The drug of choice for mushroom poisoning-AdrenalinePhysostigmineAtropineCarbachol  <response>: Ans. is c i.e., Atropine Mushroom poisoning o Depending on the toxic principal present in the paicular species, at least 3 types of mushroom poisoning is known. 1. Muscarine type early mushroom poisoning Due to Inocybe and related species. Symptoms are due to muscarinic action. Tt of choice is atropine. 2. Hallucinogenic type o It is due to muscimol and other isoxazole compounds which are present in A. muscaria. o These isoxazole compounds activate amino acid, receptors, and block muscarinic receptor in brain; and have hallucinogenic propey. o Manifestations are primarily central. o There is no specific treatment and atropine is contraindicated. o Another hallucinogenic mushroom is Psiloocybe mexicana whose active principal Psilocybine is a tryptaminergic compound this has been added to 6the of KDT. 3.Phalloidin type late mushroom poisoning o Due to peptide toxin found in A. phalloides and Galerina. o These inhibit RNA protein synthesis. o Symptoms are due to damage to the GI mucosa, liver and kidney. o Treatment is supppoive, Thiotic acid may be used. 