<prompt> Side effect of topiramate is ?Weight lossVisual impairementInsomniaHemolysis  <response>: Ans. is a i.e., Weight loss Topiramate Weak carbonic anhydrase inhibitor with broad spectrum anticonvulsant activity. Acts - prolongation of Na channel inactivation, GABA potentiation, gultamate receptor antagonism, neuronal hyperpolarisation K channels. Used in SPS, CPS, GTCS, myoclonic epilepsy, prophylaxis of migraine. Readily absorbed orally and mainly excreted in urine. T12 - 24hrs. Adverse effects impairment of attention, sedation, ataxia, word finding difficulties, poor memory, weight loss, paresthesias, and renal stones. 