<prompt> The pathogenesis of hypochromic anemia in lead poisoning is due toInhibition of enzymes involved in heme biosynthesisBinding of lead to transferrin, inhibiting the transport of ironBinding of lead to cell membrane of erythroid precursorsBinding of lead to ferritin inhibiting their breakdown into hemosiderin  <response>: Lead interferes with the synthesis of Heme. Deficiency of heme causes microcytic hypochromic anemia because heme is an integral part of hemoglobin and it is well known that hemoglobin deficiency causes microcytic hypochromic anaemia. 