<prompt> All are TRUE about amyloidosis, EXCEPT:It is an extracellular depositInsoluble polymeric protein fibrilsAmyloid fibrils share a common pleated structureThe term amyloid was coined by Lister  <response>: Amyloidosis is the extracellular deposition of insoluble polymeric protein fibrils. This disorder is due to misfolding of proteins. Eg: Alzheimers disease and other neurodegenerative diseases, Transmissible prion diseases, Ceain of the cystic fibrosis mutations. Amyloid fibrils share a common beta-pleated sheet structural conformation. It has unique staining propeies. The term amyloid was coined by Rudolf Virchow. Ref: Harrison, Edition-18, Page 942 