<prompt> Earliest evidence of healing in rickets is provided by-S. CaS. P043-Radiological examination of growing bone endsS Alkaline phosphate level  <response>: The earliest evidence of healing rickets comes from radiographs of the growing ends of bones. Concentration of calcium and phosphorus in the plasma provide an inconstant and unreliable guide. A more constant change is a decrease in the plasma alkaline phosphatase, but this does not usually occur for several weeks after adequate treatment initiated. 