<prompt> Which of the following is not a feature of chronic leukemia?Often diagnosed incidentallySplenomegaly is commonLeucocytosis with circulating blasts and cytopenias are commonLymphadenopathy is common  <response>: Presentation of leukaemia : Acute vs. Chronic Acute leukaemias Sho history of feeling unwell May present with neutropenic fever or bleeding Organ infiltration may occur: skin, gums, testes, meninges Peripheral blood usually shows leucocytosis with circulating blasts and cytopenias Chronic leukaemias Often diagnosed incidentally Usually long history of non-specific symptoms Splenomegaly is common Lymphadenopathy is common in chronic lymphocytic leukaemia Peripheral blood usually shows leucocytosis with circulating mature lymphocytes or myeloid cells; blasts are rare Ref: Leukaemia update. Pa 1: diagnosis and management ; BMJ 2013;346:f1660. 