<prompt> The occurence of hypehyroidism following administration of supplemental iodine to subjects in endemic area of iodine deficiency is due to ?Wolf-Chaikoff effectJod-Basedow effectPembeon effectGraves effect  <response>: Answer- B. Jod-Basedow effectSynonymous with iodine induced hypehyroidism and may occur in patients with multinodular goitre after intake of large amount of iodine. 