<prompt> Superantigens causes -Polyclonal activation of T-cellsStimulation of B cellsEnhancement of phagocytosisActivation of complement  <response>: Superantigens are a class of antigens that cause non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release. Superantigens bind first to the MHC Class II and then coordinate to the variable alpha or beta chain of T-cell Receptors . Ref: Ananthanarayan Panikers textbook of microbiology 9th edition pg:90 