<prompt> All are true about warfarin, exceptIt inhibits the activation of vitamin K dependent cloting factorsIts half life is 36 hoursIt can cross placentaIts dose is increased in liver disease  <response>: It;s dose should be reduced in liver and renal impairment as it is metabolized by glucoronide conjugation and is excreted by urine. From medical pharmacology padmaja 4th edition Page no 339,341 