<prompt>  A 35-year-old male patient presented with a history of jaundice for 15 days. The onset was preceded by a prodromal illness. His serum tested positive for HBsAg. A clinical diagnosis of acute Hepatitis B was made. What should be the next best confirmatory investigation -Antii-HBeAg antibodyHBe antigenAnti-HBe IgM antibodyHBV DNA by PCR 