<prompt> Acantholytic cells are seen inPemphigus vulgarisBullous pemphigoidCicatricial pemphigoidDermatitis herpetiformis  <response>: Ans. a Pemphigus vulgarisHarrison 19th ed. 370 The rounded keratinocytes with hyperchromatic nuclei and perinuclear halo due to condensing of cytoplasm in periphery are called acantholytic cells. It is seen in case of pemphigus vulgaris Acantholytic cells can be demonstrated in bed side Tzanck test. 