<prompt> Half-life of carbimazole is4 hours8 hours16 hours24 hours  <response>: Carbimazole has a half-life of 5.3 to 5.4 hours. It is possible that the plasma half-life may also be prolonged by renal or hepatic disease. See section 4.2. Thiamazole crosses the placenta and appears in breast milk. Ref: kd tRIPATHI 8TH ED. 