<prompt> Desmoglein is an Autoantigen inPemphigusEczemaSarcoidosisVitiligo  <response>: Ans. is a i.e., Pemphigus Desmosomes o Desmosomes are the major adhesion complex in the epidermis, anchoring keratin intermediate filaments IFs to the cell membrane and bridging adjacent keratinocytes, and allowing cells to withstand trauma. o The main components of desmosomes consist of the products of three gene superfamilies : - Desmosomal cadherins They are calcium ion-dependent cell adhesion molecules that show homophilic adhesions i.e. a cadherin molecule of one cell binds to the same molecule on another cell. They include Desmogleins 1-4 Dsgl-Dsg4 Desmocollins 1-3 Dscl-Dsc3 Armadillo proteins Plakoglobins Pgs Plakophilin Pkps 1-3 3 Plakins Desmoplakins DPS. Ptectin Envoplakin Periplakin Antigen defect Disease Dsg 1 Pemphigus violaceus Dsg 3 Pemphigus Vulgaris Dsc 1 Subcorneal pustular dermatosis Dpk 1 2 Erythema multi forme Envoplakin Periplakin Perineoplastic pemphigus 