<prompt> Side effects of Pilocarpine are AEShallow anterior chamberPunctate stenosisFollicular conjunctivitisPosterior synechia  <response>: Most guides have given option a as the answer.I have done extensive search on this. First you see the topical adverse effects of parasympathomimetic antiglaucoma drugs from yanoff Duker :-Directly acting cholinergic agonists like pilocarpine, carbachol Miosis, uveitis, browache, cataracts, myopia, retinal detachment, colour vision changes, angle closure, ocular cicatracial pemphigoid.Indirectly acting anticholineesterases like demecarium :- Intense miosis, iris pigment cysts, punctal stenosis, myopia, cataract, retinal detachment, angle closure.Now see each option sequentially :-Option 1Pilocarpine can cause shallow anterior chamber :-The use of pilocarpine is somewhat paradoxical since it is known to cause further shallowing of anterior chamber. Evidence - based ophthalmology.Now you must be thinking then why pilocarpine is the drug of choice for angle closure glaucoma. Pilocarpine works by helping to open the angle by tensing the iris-diaphragm and pulling on the scleral spur. It may also help to resolve relative pupil block.Option 2Punctal stenosis is caused by indirect cholinomimetic cholinesterase not by direct cholinomimetic pilocarpine.Option 3Rarely, pilocarpine can cause follicular conjunctivitis :-Pilocarpine and carbachol may both cause conjunctival follicle. Clinical ophthalmology.Option 4Miotics pilocarpine makes the iris thin and pulls it away from lens removing the pupillary block, increasing the chances of posterior synechiae due to stretching increased surface of iris and restoring aqueous flow by opening irido-corneal angle. 