<prompt> Which among the following statements is wrong ?Light chains are synthesised in slight excess normally in plasma cellsQualitative assessment of M component can be done by electrophoresisM components are detected in chronic myeloid leukaemiaIn 20 myelomas, only light chains are produced  <response>: Qualitative assessment of M component is done by immunoelectrophoresis. Electrophoresis is used for quantitative assessment of M component. M component can also be detected in other lymphoid malignancies, CML, Ca breast, colon cancer , non neoplastic condition like cirrhosis, sarcoidosis, rheumatoid ahritis, myasthenia gravis. 