<prompt> IL-2 is secreted by -CD4 lymphocytesCD8 cellsMacrophagesNeutrophils  <response>: Option 1 IL-2 Previously called T-cell growth factor is a protein produced mainly by helper T 1 cells. It is a major T-cell growth factor. It stimulates both helper and cytotoxic T cells to grow. It also promotes the growth of B cells and can activate natural killer NK cells and monocytes. IL-2 acts on T cells in an autocrine fashion. Activation of T cells results in expression of IL-2R and the production of IL-2. Option 2, 3, 4 IL-1: Produced by all nucleatedcells Mainly by APCs such asMacrophages, monocytesdendritic cell, B-cells andendothelial cell. IL-6: TH 2 cells, macrophages IL-8: Macrophages, endothelial cells IL-12: Macrophages 