<prompt> Typhoid perforation occurs duringIst week2nd week3rd week4th week  <response>: Enteric fever is a potentially life - threatening systemic disease characterized by fever and abdominal pain. It is caused by Salmonella typhi or paratyphi. Typhoid is the MC cause of ileal perforation in tropical countries India.Pathology : Ulceration and necrosis of ileocecal Peyers patches. The ulcer is parallel to the long axis of the gut and is usually situated in the lower ileum longitudinal ulcers. Perforation of a typhoid ulcer usually occurs during the third week and is occasionally the first sign of the disease.Clinical Features : Fever and abdominal pain are hallmark symptoms. Non-specific symptoms : Headache, cough, sweating, myalgia, arthralgia, fatigue. Paralytic ileus is the MC complication of typhoid. Intestinal hemorrhage 2nd MC may be the leading symptom. 