<prompt> Most common type of heavy chain disease is?Alpha chain diseaseGamma chain diseaseMu chain diseaseDelta chain disease  <response>: Ans. is a i.e., Alpha chain disease Heavy chain diseases are plasma cell disorders that are typically malignant. They are a form of paraproteinemias in which incomplete monoclonal immunoglobulins true paraproteins are produced. They consist of only heavy chain components either alpha , gamma , mu , or delta without light chains. The clinical picture is more like lymphoma than multiple myeloma There are four forms:i Alpha chain disease Seligmanns disease- most common typeii Gamma chain disease Franklins diseaseiii Mu chain diseaseiv Delta chain disease 