<prompt> ;Cystosarcoma phyllodes; is best treated bySimpel mastectomyLumpectomyRadiotherapyRadical mastectomy  <response>: Cystosarcoma phylloides are not simply giant fibroadenoma. They show a wide spectrum of activity, varying from almost a benign condition 85 to a locally aggressive and sometimes metastatic tumour 15. Depending on mitotic index and degree of pleomorphism they are graded as low grade to high grade tumours. Treatment; Excision or subcutaneous or simple mastectomy is done. If malignant sarcoma, total mastectomy is indicated Ref; page no; 520 5th edition of SRB;S manual of Surgery 