<prompt> Parathyroid adenoma most commonly involves which of the following siteThyroid substanceSuperior parathyroid lobeInferior parathyroid lobeIn the mediastinum  <response>: Adenomas are most often located in the inferior parathyroid glands, but in 6-10 of patients, parathyroid adenomas may be located in the thymus, the thyroid, the pericardium, or behind the esophagus. 