<prompt> Amiloride can cause hyperkalemia due to its action on :Electrogenic K channelsElectrogenic Na channelsNon electrogenic Na-C1- symporterH-K ATPase  <response>: Amiloride and triamterene are K sparing diuretics that act by inhibiting epithelial Na channels.In the distal tubules and collecting ducts, three separate channels are present one for Na, K and H each. Aldosterone acts on DCT and CD to cause reabsorption of Na. This generates a lumen negative potential difference across the membrane of this part of the nephron. To maintain the electric neutrality, K and H are secreted in the lumen. 