<prompt> Roflumilast is introduced in management of COPD in?Group AGroup BGroup CGroup D  <response>: Group A Low Risk, low symptom Bronchodilator Group B Low Risk, High symptom LABALAMA, if failed- LAMALABA Group C High Risk, Low symptom LAMALABA or LABAICS Group D High Risk, High symptom LAMALABAICS symptoms persists Phosphodiesterase inhibitor Roflumilast or Macrolides 