<prompt> All of the following statements about carcinoid syndrome are true except:Midgut carcinoids produce typical carcinoid syndromePlasma serotonin levels may be normal in atypical carcinoid syndromeMetastasis to bone is common in Midgut CarcinoidsCarcinoid Syndrome is rare in Hindgut Carcinoids  <response>: Answer is C Metastasis to bone is common in Midgut Carcinoids: Palliative Care Oxford University Press, 2009 452; Multiple references Metastasis to bone is rare in Midgut Carcinoids and is Common in Foregut Carcinoids. Features Foregut Midgut Hindgut Site Esophagus Jejunum Transverse ColonDistal Stomach Ileum Descending Colon Duodenum Proximal Appendix Rectum Liver; Gallbladder Meckels Diveiculum Pancreas Ascending Colon Respiratory tract Transverse Colon Proximal Argentaffin Stain Negative Positive ? Carcinoid Syndrome Atypical Typical Syndrome is Rare Prolonged purple flush; Sho pink red flushes; Headache; , lacrimation; Diarrhoea; Wheezing; Bronchoconstriction Dyspnea; Cardiac Fibrosis; Pallegra Metastasis to Bone Common Rare Common Plasma Serotonin Normal Elevated ? Typical Urinary 5-HTP 5-HIAA, 5HT Rarely 5HT Metabolite 