<prompt> A pt. presents with hematuria of several days and dysmorphic RBC casts in urine. The site of origin is :KidneyUreterBladderUrethra  <response>: Ans. is a ie kidney Isolated microscopic hematuria can be a manifestation of glomerular disease. The RBCs of glomerular origin are often dysmorphic. Hematuria with dysmorphic RBCs, RBC casts and protein excretion 500 mgday is virtually diagnostic of glomerulonephritis.SoDysmorphic RBCs - origin is kidneyRBCs cast - origin is kidney Broad cast - Seen in chronic renal diseases.Granular cast - ARFWaxy casts - seen in chronic renal disease.WBC casts - pyelonephritis.Also rememberHematuria is defined as two to five RBCs per high power fieldNormal RBCs excretion is upto 2 million RBCsday 