<prompt> De-Quervains disease classically affects the -Flexor pollicis longus and brevisExtensor carpi radialis and extensor pollicis longusAbductor pollicis longus and brevisExtensor pollicis brevis and abductor pollicis longus  <response>: De-Quervians tenovaginitis is characterized by pain over the styloid process of the radius and palpable thickening in the course of the abductor pollicis longus and extensor pollicis brevis tendons. 