<prompt> The following statement is false regarding Graves diseaseHyperophyhyperplasia is due to TSH-RAbsCardiac failure is commonGoiter is diffuse and vascularRemissions and exacerbations are not infrequent  <response>: Grave;s Disease Diffuse Toxic GoiterMC cause of hypehyroidism, caused by stimulatory autoantibodies to TSH-RMore common in females with peak incidence between 40-60 yrsClinical FeaturesHypehyroid symptoms- heat intolerance, increased sweating and thirst, weight loss despite adequate caloric intake.Symptoms of adrenergic stimulation- palpitations, nervousness, fatigue, emotional lability, hyperkinesis and tremorOlder patients present with CVS complications CVF and CHFIn Graves disease- Cardiac toxicity is less and CNS toxicity is more. In secondary thyrotoxicosis cardiac toxicity is more common.Refer: Schwazs Principles of surgery, 9th edition, pg no: 1353-1354 