<prompt> Which one of the following diseases characteristically causes fatty change in liver ?Hepatitis B virus infectionWilsons diseaseHepatitis C virus infectionChronic alcoholism  <response>: Ans. is d i.e., Chronic alcoholismAlcoholic liver disease ALD is the most frequent secondary fatty liver disease. Secondary fatty liver can also occur in chronic Viral hepatitis C HCV, chronic viral hepatitis B HBV, chronic autoimmune hepatitis AIH, and Wilsons disease - although fatty liver may be seen secondary to all options mentioned in the question chronic alcoholism being the most common cause is the single best answer here.Following information have been added in 8thle of Robbins Non alcoholic fatty liver disease NAFLD o It has become the most common cause of chronic liver disease in united states.o NAFLD includes:i Simple hepatic steatosisStable conditionsii Steatosis with inflammationiii Non-alcholic steohepatitis NASH -- Can progress to cirrhosiso NAFLD is the most common cause of cryptogenic cirrhosis cirrhosis of unknown origin. 