<prompt> Which of the following is not a ourable prognostic marker in pediatric acute lymphoblastic leukemia ALL?Hypodiploidy2-10 years of ageLow WBC countt12;21  <response>: Favourable prognostic markers in pediatric ALL include age between 2 and 10 years a low white cell count hyperdiploidy trisomy of chromosomes 4, 7, and 10 the presence of a t12;21 Several factors are associated with a worse prognosis: age younger than 2 years, largely because of the strong association of infantile ALL with translocations involving the MLL gene presentation in adolescence or adulthood peripheral blood blast counts greater than 100,000, which probably reflects a high tumor burden. 