<prompt> Bone resorption is enhanced byPGD2PDF2PGE2PGI2  <response>: Bone resorption is increased by prostaglandin E2. Increased PGE2 stimulates binding of RANK ligand to RANK- stimulating osteoclast-causing resorption REF.Essential of medical pharmacology K D TRIPATHI 6 Edition, Page No - 325 