<prompt> IL - I produces -T lymphocyte activationDelayed wound healingIncreased pain perceptionDecreased PMN release from bone marrow  <response>: Interleukin -1 Also known as leucocyte activating factor LAF or B cell activating factor BAF.Principally secreted by macrophages and monocytes, and epithelial cells.Other sources are B lymphocytes, fibroblasts and endothelial cells.Immunological effects-- Activation of T cells for the production of IL - 2.- B cell proliferation and antibody synthesis- Neutrophil chemotaxis and increased PMN release from bone marrow.- Increases body temperature important endogenous pyrogen.- Bone marrow cell proliferation- Induction of acute phase protein. 