<prompt> First centre that get activated before skilled voluntary movements is?Neo cortexHypothalamusPonsMedulla  <response>: ANSWER: A Neo cortexREF: Ganongs 22nd edition page 203Repeat from June 2011The lateral corticospinal tract is concerned with skilled movementsSee APPENDIX-15 for detailsOrigin: primary motor cortex 30, premotor and supplementary motor area 30 and somatosensory areas posterior to central sulcus 40It passes through posterior limb ofg internal capsule and then forms the pyramid of medulla Lateral corticospinal tractVentral corticospinal tract 80 fibres cross in medulla to opposite side to form lateral corticospinal tract Concerned with skilled movements and end directly on motor neurons in humans Uncrossed fibres form ventral corticospinal tract Dont cross until it reaches level of musclesGiant cells of betz are the originating cells of the tract located in primary motor cortex. 