<prompt> All of the following statements regarding volume of distribution are true except:Half life is usually propoional to VdCalculated by t12 multiplied by log2Skeletal muscle relaxants have low VdHigh plasma protein bound drugs have low Vd  <response>: Vd Amount of drug given Plasma concentration . So, option B is wrong.t12 0.693 Vd Clearance So, Half life is directly propoional to volume of distribution. Skeletal muscle relaxants have low Vd so that they cant go to brain etc. High plasma protein bound drugs are less distributed so less volume of distribution. 