<prompt> Sulfasalazine exes its primary action in ulcerative colitis by :Folic acid synthesisFormation of prostaglandins PGInhibition of NF-KB ActivationFormation of interleukins  <response>: MOA Inhibition of NF-KB Activation Inhibition of PG synthesis Scavenging of Free radicals 5-ASA compounds exe its local anti-inflammatory effect by inhibiting leukotriene production PG synthesis by inhibition of 5-lipooxygenase activity; also inhibits the production of IL-1 and TNF. Commonly Used 5-ASA Formulations in IBD Sulfasalazine Oral mesalamine agents Azo compounds: Balsalazide, Olsalazine 