<prompt> Treatment of hyperkinetic syndrome includesImipramineMethylphenidateHaloperidolClozapine  <response>: CNS stimulants are the first choice agents in that they have been shown to have greatest efficacy with generally mild tolerable side effect. Excellant safety record is documented fro sho and sustained release preparations of Methylphenidate, dextroamphetamine and dextroamphetamine and amphetamine salt combinations. Methylphenidate- 0.3-1 mgkg tid; upto 60mgday. Both dexamphetamine and methylphenidate act on the reticular activating system, causing stimulation of the inhibitory influences on the cerebral coex, thus decreasing hyperactivity andor distractibility Ref: Synopsis of Psychiatry, 11e, pg 1175. A sho textbook of psychiatry, Niraj Ahuja,7th edition, pg no 167 