<prompt> Which of the following is true about alpha 1 antitrypsinInhibits elastaseInhibits trypsinogen activation in pancreasInhibits trypsin activating proteaseInhibits chymotrypsin  <response>: alpha 1 antitrypsin deficiency is an Autosomal recessive disorder It is synthesised in the liver Deficiecy of alpha 1 antitrypsin can cause panacinar emphysema and can affect the liver. Normal wild genotype of PiMM alpha 1 antitrypsin deficiency can cause globular cytoplasmic inclusions in hepatocytes These inclusions are PAS positive and diastase resistant Ref:- Robbins Basic Pathology 10th Edition; Pg num:- 658,659 