<prompt> Van Buchems syndrome is characterized by all exceptOvergrowthDistrotion of mandibleFacial PalsyIncreased acid phosphatase  <response>: Ans. is b i.e., Distoion of mandible Van Buchems disease is a rare hereditary disorder of the skeletal system that is characterized by progressive osteosclerosis paicularly in the skull mandible. Consequence of increased bone mass usually include facial distoions and compression of cranial nerves which may lead to deafness blindness. 