<prompt> 6 months old infant with Hb of 6 gm has anaemic features with peripheral blood showing target cells. Family history of similar complaints is Positive. Diagnosis can be best done with which of the following:Hb electrophoresisELISACoombs TestOsmotic fragility  <response>: Ans. is a i.e. Hb Electrophoresis Ref. Harrison, 16e, 595 15e, p. 681, Nelson 17e, p 1630-1632.Presence of:Anaemia Hb 6Target cellsIncrease reticulocytes suggests the diagnosis of thalassemia.Thalassemia is a hemoglobin disorder Hemoglobin disorders are diagnosed by electrophoresis.Diagnosis of thalassemia is confirmed by serum electrophoresis.The finding is- Increase Hb A2Increase Hb FOther conditions in which Target cells are seenLiver diseaseHemoglobin C and S disease 