<prompt> Which of the following condition is associated with an increased risk of developing adenocarcinoma of esophagus?Barrets esophagusLong standing achalasiaCorrosive structureAlcohol abuse  <response>: The metaplasia of esophageal squamous epithelium to columnar epithelium Barretts esophagus is a complication of severe reflux esophagitis, and is a risk factor for esophageal adenocarcinoma. Endoscopic biopsy is the gold standard for confirmation of Barretts esophagus. The hallmark of Barrets esophagus is the presence of mucus secreting goblet cells. Ref: Schwazs Principles of Surgery, 9th Edition, Chapter 25 