<prompt> All of the following conditions are contraindicated or likely to worsen in a case of Primary Open Angle Glaucoma, when treated with Timolol maleate 0.5 eye drops, exceptHypeensionHypercholesterolemiaDepressionBronchial asthma  <response>: A i.e. Hypeension Topical nonselective f3 blockers e.g. timolol are contraindicated in asthma Q, COPD, CHF, sinus bradycardia AV blocks; where as selective 31 blockers e.g. betaxolol are CI in sinus bradycardia atrioventricular blocks only. 