<prompt> Duodenal adenocarcinoma -a Most common small bowel carcinomab Periampullary carcinomac Jaundice anemia - most common symptomd Local resection - curativeacbcadb  <response>: Duodenum is MC site of small intestinal adenocarcinoma 15 in the proximal; 40 in the middle and 45 in the distal duodenum MC Resectability and prognosis are better than other upper GI cancers.Clinical Features Most often presents as obstruction, with nausea, vomiting, and abdominal pain as the most frequent symptoms. Anemia from bleeding and biliary or pancreatic obstructive symptoms can also be seen on initial presentation if the tumor is located within the periampullary region.Diagnosis Endoscopy is the diagnostic test of choice for duodenal tumors, which allows for direct visualization and biopsy as needed.Treatment For 1st or 2nd portion: Whipple procedure For 3rd or 4th portion: Segmental duodenal resection 