<prompt> Which of the following physical signs is seen in a patient with severe aoic stenosis:Opening snapDiastolic rumbleHolosystolic murmurDelayed peak of systolic murmur  <response>: Answer is D Delayed peak of systolic murmur The ejection systolic murmur stas after the ejection click reaches a peak in midsystole. With increasing severity of aoic stenosis the peak gets delayed so that the maximum intensity of the murmur is closer to the end rather than being midsystolic. 