<prompt> Which of the following statements about anti-epileptics is falsePhenytoin and carbamazepine act by prolonging Na channel activationCarbamazepine is also used in trigeminal neuralgiasDiazepam is an anti-epilepticLamotrigine acts by GABA mediated Cl- channel opening  <response>: Ans. a. Phenytoin and carbamazepine act by prolonging Na channel activation Phenytoin and carbamazepine act by prolonging Na channel activation, it is a false statement. Phenytoin and carbamazepine limit the repetitive firing of action potentials evoked by sustained depolarization. This effect is mediated by slowing of the rate of recovery of voltage-activated Na channels from inactivation, an action that is both voltage-and use-dependent greater effects if membrane is depolarized.- 