<prompt> All of the following statement are true regarding Q fever except -It is zoonotic diseaseHuman disease is characterized by an interstitial pneumoniaNo rash is seenWeil-felix reaction is very useful for diagnosis  <response>: Q fever:- Highly infectious zoonotic disease with world wide distribution. Occurs mainly in persons associated with sheep, goat ,cattle etc. Causative agent-Coxiella burnetti. It is found in ticks which act as vectors as well as reservoirs. Animal host- cattle,sheep, goat, ticks etc. The placenta of infected cows and sheep contain infectious agent which may create infectious aerosols during paurition. Mode of transmission:- No ahropod involved in transmission. Inhalation of infected dust from soil previously contaminated by urinefeces of diseased animals. The organism can also be transmitted through aerosols. Also gain entry through abrasions,conjunctivae or ingestion of contaminated foods. Incubation period-2-3 weeks. Clinical features-fever chills, general malaise and headache. The clinical picture is one of influenza non bacterial pneumonia. No rash local lesions. The infection can cause pneumonia, encephalitis, endocarditis. Treatment- doxycycline 18 months Pasteurisation boiling of milk. Adequate disinfection and disposal of products. Inactivated Coxiella vaccine has been prepared to protect occuppationally exposed workers. Reference: park;s textbook of preventive and social medicine, 23rd edition, pg no.301 