<prompt> Which of the following drugs acts on trabecular mesh-work and affects the aqueous outflowTimololPilocarpineBrimonidineBrinzolamide  <response>: Pilocarpine increases trabecular outflow by increasing ciliary tone. Timolol and Brinzolamide decreases the aqueous formation.Brimonidine act by augmenting uveoscleral outflow. 