<prompt> The mechanism of action of cyclosporine is:Inhibits IL-2 receptorsInhibits TNF alphaDecrease in transcription of IL-2 geneTargets inactivated T cells  <response>: Cyclosporine calcineurin inhibitor inhibits the dephosphorylation of NFAT leading to blocked of T cell activation by preventing IL2 Transcription. Tacrolimus FK506:- is also calcineurin inhibitor which binds FK506 binding protein. IL2 receptor are blocked by Basiliximab, Daclizumab. TNF alphaBlocker :- Infliximab 