<prompt> Congenital cause of hypercoagulable states are all except aEURProtein C deficiencyProtein S deficiencyMTHFR mutationMTHFR mutation  <response>: Lupus anticoagulant Ref: Harrison I7e p. 7321 Causes of Hy ercoa ulable state Congenital Factor V Leiden 5 of the population are heterozygous for FVL. Prothrombin mutation G202 WA, 5UTR. High homocysteine levels due to MTHFR mutation0 Sickle-cell disease only small risk Antithrombin III deficiency. Protein C deficiencyQ. Protein S deficiency0. Plasminogen and fibrinolysis disorders very rare Acquired Antiphospholipid antibodies - Anti-cardiolipin antibodies andor - Lupus anticoagulants Heparin-induced thrombocytopenia Paroxysmal nocturnal hemoglobinuria Nephrotic syndrome Hyperestrogenemia Estrogen-containing hormonal contraceptives Tobacco smoking Hyperhomocysteinemia due to vitamin I312 and folic acid deficiency. 