<prompt> A 46 years old lady has abnormal uterine bleeding with simple hyperplasia of endometrium. The treatment of choice would be: March 2005Total HysterectomyProgestronEstrogen progestogenEstrogen  <response>: Ans. A: Total Hysterectomy Stage 0 of endometrial carcinoma-Endometrial hyperplasia Simple endometrial hyperplasia develops malignancy in 10-20 of cases whereas in atypical hyperplasia develops malignancy in 60-70 Total hysterectomy with removal of both the ovaries is treatment of choice in elderly patients whereas younger patients need progesterone therapy for 6-12 months and lifelong follow-up 