<prompt> Zileuton, a 5-lipooxigenase inhibitor, acts by which of the following mechanisms?LT C4 synthesis inhibitorD4 synthesis inhibitorLT B4 synthesis inhibitorAll of the above  <response>: Ans. d All of the above Ref. KDT, Pharmacology, 6th ed. 175, 223ZILEUTON 5-Lipoxygenase inhibitor and blocks LTC4, LTD4 as well as LTB4 Synthesis Duration of action - Short 3-4 hrs Adverse effect - Hepatotoxicity.MONTELEUKAST, ZAFIRLUKAST Cys LT1 receptor antagonist used in asthma prophylaxis Side effects:- Eosinophilia, Neuropathy, Churg-Strauss disease 