<prompt> Iron deficiency is best demonstrated by:RDWS. ferritinBM examinationd...  <response>: Ans b Se FerritinRef: Davidson, 21 edpg. 1018Ferritin n 50 - 200 microgA measure of iron stores in the tissue and is the single best test to confirm iron deficiency Less than normal value of Se. ferritin is seen in:1. Iron deficiency2. Hypothyroidism3. Vitamin c deficiency Raised Se.ferritin value is seen in:1. Liver disease2. As an acute phase responseS. Iron n 50-150 microgdLow in Iron deficiency anaemia 30; also in anaemia of chronic disease, during acute phase response.Se. iron is raised in liver disease and also in haemolysisTIBC n 300-360 microgdlHigh in iron deficiency anaemia Low in anaemia of chronic diseaseLow iron- Low TIBC ACDLow iron High TIBC IDATransferrin saturation n 30-5016 is consistent with IDA but less specific than ferritin.Transferrin saturation is less in ACD IDA; normal orincreased in thalassaemia sideroblastic anaemiaTransferrin levels are low in malnutrition. Nephrotic syndrome,liver disease as well as during acute phaseresponse.Transferrin levels are high in pregnancy OCP use.Red cell distribution width RDW n 11.5 - 14.5Coefficient of variation of RBC volume. Normal RDW - anaemia of chronic disease, aplastic anaemiaIncreased RDW - iron deficiency, B12 defeciency, folic acid deficiency 