<prompt> Which of the following statement is TRUE about Bohrs effect?Decreased affinity of Hb to 02 is associated with decreased pH increased C02Decreased affinity of Hb to 02 is associated with increased pH decreased C02Decreased affinity of Hb to 02 is associated with decreased pH C02Decreased affinity of Hb to 02 is associated with increased pH C02  <response>: The decrease in O2 affinity of hemoglobin when the pH of blood falls is called the Bohr effect. It is closely related to the fact that deoxygenated hemoglobin deoxyhemoglobin binds H more actively than does oxygenated hemoglobin oxyhemoglobin. The pH of blood falls as its CO2 content increases, so that when the PCO2 rises, the curve shifts to the right and the P50 rises. Ref: Barrett K.E., Barman S.M., Boitano S., Brooks H.L. 2012. Chapter 35. Gas Transpo pH. In K.E. Barrett, S.M. Barman, S. Boitano, H.L. Brooks Eds, Ganongs Review of Medical Physiology, 24e. 