<prompt> Nigro protocol is for which carcinomaAnalColonHepatocellularPancreatic  <response>: Nigro protocol or Nigro Regime for Anal Carcinoma Norman Nigro, et al 1974: Initial radiotherapy for 3 weeks 3000 rads 30 Gy total to perineum and pelvis Then chemotherapy--5 FU, for 4-5 days; is a radiosensitizer, staed on 1st day of as 1000 mgm2 continuous infusion. Mitomycin C is 15 mgm2 as single dose on 1st day of Later after 3 weeks abdominoperineal resection APR with colostomy in case of persistent or recurrent disease. Reference : page 987 SRBs manual of surgery 5th edition 