<prompt> HIV infects most commonlyCD4helper cellsCD8cellsMacrophageNeutrophil  <response>: Ans. is a i.e CD4 helper cells CD4 T lymphocytes and CD4 cells of monocyte lineage are the principal targets of HIV.Virtually any cell that expresses the CD4molecule together with Coreceptor molecules can potentially be infected with H.I.V. e.g.Dendritic cellsLangerhans cellsEven Megakaryocytes, eosinophilis, Astrocytes, oligodendrocytes, microglial cells, CD4 T cells can also be infected with HIV. 