<prompt> Hyperprolactinoma causesInter menstrual bleedingProlonged menstruationOligomenorrheaPolymenorrhea  <response>: Oligomenorhea: 2287-88- H18th edition; 788-Davidson 21stHYPER PROLACTINEMIA Hyper prolactinemia is the most common pituitary hormone hyper secretion syndrome in both men and women PRL- secreting pituitary adenoma Prolactinomas are the most common cause of PRL levels 200 mgL Pregnancy and lactation are the important physiologic causes of hyperprolactinemia Amenorrhea, galactorrhea and infertility are the hall marks of hyperprolactinemia in women More commonly hyperprolactinemia develops later in life and leads to oligo menorrhea and ultimately to amenorrhea Decreased libido, weight gain and mild hirsutism may also complainMen- Diminished libido , infertility and visual loss, impotence and oligospermia True galactorrhea is uncommon in men hypogonadism, osteopenia, reduced muscle mass and decreased beard growth 