<prompt> Earliest sign of papilloedema -Less of pulsationBlurring of disc marginObliteration of cupCotton-wool spots  <response>: Early incipient papilloedema is characterised by, obscuration of disc margins nasal margins involved first , then superior , inferior and temporal blurring of peripapillary nerve fibre layer absence of spontaneous venous pulsations at the disc mild hypaeremia Refer comprehensive ophthalmology 6 th edition A K Khurana, page no. 324 