<prompt> Which of the following bacteria grows better in alkaline pH?Vibrio choleraePseudomonasShigellaSalmonella  <response>: Ans. a Vibrio cholerae. Textbook of Microbiology by Anantanarayan, 6th281VIBRIO CHOLERAE Gram-negative, strongly aerobic, Pleomorphic bacteria. Vibrio lyse when injected intraperitoneally into specifically immunized guinea pigs Pfieffers phenomenon. Fish in stream appearance. Darting motility swam of gnats. Grow better in alkaline medium. NaCl required for optimal growth. Bile salt agar TCBS agar selective mediaAIIMS Nov 2007 Alkaline peptone water--enrichment media Cholera red reaction -Indole is formed nitrates are reduced to nitrites. Vibrio cholerae toxin permanently activates Gs, causing rice-water diarrhea. ADP ribosylation of G protein stimulates adenylyl cyclase; -pumping of Cl into gut and -Na absorption. H2O moves into gut lumen; causes voluminous rice-water diarrhea. 