<prompt> C-3 nephritic factor is associated with which of the following conditions?MPGN Type 1MPGN Type 2Membranous nephropathyMinimal change disease  <response>: Dense-Deposit Disease type II MPGN Resulting in excessive activation of the alternative complement pathway. Normally, this C3 convease is labile, but more than 70 of patients with dense-deposit disease have a circulating autoantibody termed C3 nephritic factor C3NeF that binds the alternative pathway C3 convease and protects it from inactivation. 