<prompt> The effect of progesterone on lipidsLowers LDL, increases HDLLowers LDL and HDLLowers HDL and increases LDLIncreases LDL and HDL  <response>: While part of the administered progestogen is metabolized to oestrogen, it is also partly metabolized to testosterone. If administered to a patient during pregnancy, some progestogens have virilizing effect upon a female fetus. Lipid metabolism decreases HDL but increases low-density lipoprotein. Thus, it is harmful to the heart.It improves the immune response 