<prompt> Schistocytes in peripheral smear are seen in all except:DICSickle cell anemiaTTPHUS  <response>: Schistocyte is fragmented RBC which is seen in any condition where there is micro and macro angiopathic hemolytic anemias. Microangiopathic hemolytic anemia is most commonly seen with DIC, TTP, hemolytic-uremic syndrome HUS, malignant HTN, SLE, and disseminated cancer. Macroangiopathic schistocyte is seen in patient with prosthetic hea valve. Sickle cell anemia: Blockage of vessels by sickled cells causes pain crises and tissue infarction, paicularly of the marrow and spleen. Red cell membrane damage caused by repeated bouts of sickling results in a moderate to severe hemolytic anemia. 