<prompt> Absolute contraindication to thrombolytic therapy isPregnancyHistory of hemorrhagic stroke in past one yearPatients on nitratesHypertension  <response>: Ans. b History of hemorrhagic stroke in past one year. Ref. Harrisons Medicine - 18thTable 370-1.Thrombolytic therapyIndicationContraindicationClinical diagnosis of strokeOnset of symptoms to time of drug administration 3 hCT scan showing no hemorrhage or edema of 13 of the MCA territoryAge 18 yearsConsent by patient or surrogateSustained BP 185110 mm Hg despite treatmentPlatelets 100,000; HCT 25; glucose 50 or 400 mgdLUse of heparin within 48 h and prolonged PTT, or elevated INRRapidly improving symptomsPrior stroke or head injury within 3 months; prior intracranial hemorrhageMajor surgery in preceding 14 daysMinor stroke symptomsGastrointestinal bleeding in preceding 21 daysRecent myocardial infarctionComa or stupor 