<prompt> Which of the following drug is an inverse agonist at H3 receptors used for Narcolepsy?DexmedetomidinePitolisantIcatibontSecukinumab  <response>: Pitolisant Tiprolisant is a inverse agonist of H3 receptors approved for Narcolepsy. H3 receptors are presynaptic receptors and inverse agonist will lead to increased histamine release and promote wakefulness. 