<prompt> Which of the following characteristics of Disseminated Intravascular Coagulation DIC makes it distinguished from Thrombotic Thrombocytopenic Purpura TTP?Brisk ReticulocytosisThe Number of SchistocytesReduction of Coagulation FactorSignificant Thrombocytopenia  <response>: A diagnosis of TTP is made based on the patients clinical presentation and the suppoive laboratory data. Disseminated Intravascular Coagulation is a close differential diagnosis of TTP. Often it is very difficult to distinguish. The following features helps to distinguish DIC from TTP. PT and APTT are increased in DIC Fibrinogen levels are decreased However one should keep in mind that there is no one test that can be diagnostic of DIC. Ref: Davidsons Medicine, 19th Edition, Page 610, 952-953 