<prompt> Schiller duval bodies seen in: REPEAT 2013Endodermal sinus tumourEmbryonal carcinomaDermoid cystBrenner tumour  <response>: Ans: A Endodermal sinus tumour Ref: Dm to Textbook of Gynecology 5th edition pg.368Explanation: Schiller duval bodies are characteristic histological feature of endodermal sinus tumour.They are tuft of vascular tissue inside cystic spaces lined by flattened epithelium.ENDODERMAL SINUS TUMOUROriginate from multipotential embryonal tissue as a result of selective differentiation of yolk sac structuresPeak - 15 to 20 years of ageSecond most common malignant germ cell tumour of ovaryUnilateral, solid. 10 cms diameterMicro-schiller duval bodies, eosinophilic hyaline bodies containing alphaproteinAssociated with dysgerminomaTreatment- surgical staging and unilateral salpingo oophenectomyCombination chemotherapy - POMB-ACE regimen cyclophosphamide, vincristine, methotrexate, bleomycin, actinomycin D, cisplatin. etoposide VAC regimen. VBP regimenTumor marker- alphafetoprotein 20 microgmml. Elevated alpha 1 antitrypsinRespond well to chemotherapy and good survival rate 