<prompt> Diacetylmonoxime are contraindicated in which poisoining ?MalathionParathionPropxurTIK-20  <response>: Oximes are used to restore neuromuscular transmission only in case of organophosphate poisoning. These act by reactivating AchE enzyme. 2 oximes : PAM Pralidoxime - It only acts in periphery and does not enter brain. DAM Diacetylmonoxime - Acts in periphery as well as in brain. Oximes are not useful in case of carbamate posionings eg. physostigmine, neostigmine, carbaryl, propoxur because here the anionic site of the enzyme is not free to provide attachment to it. It is rather contraindicated in carbamate poisoning, because it has weak anti-ChE activity of its own too. 