<prompt> Treatment of choice in complicated Plasmodium falciparum isChloroquineQuinineArtemetherArtesunate  <response>: Artesunate 1288-90-H17th Artesunate is the treatment of choice for severe falciparum malaria 1323-24-CMDT-09Treatment of MalariaClinical settingDrug TherapyAlternative drugs Chloroquine sensitiveP- falciparum andP. malaria infectionsChloroquine Plasmodium vivax and P. ovale infectionsChloroquine then If G6PD normal primaquine- Uncomplicated infections with chloroquine resistantP. falciparumQuinine sulfate plus Doxycycycline or Clinidamycin for 7 days orFansidar - three tablets onceMalarone or Mefloquine orAtcsunate or artermether orCortem Severe or complicated infections with P. falciparumArtesunateQuinidine gluconate orArtemether IV Artesunate, a water soluble artemisinin derivative has been shown to reduce mortality rates in severe falciparum malaria by 35 from rates obtained with quinine. Artesunate has therefore become the drug of choice 