<prompt> Which is true regarding rheumatoid arthritis -Small and large joints are affected mostlyYounger females are affected more commonlyDiagnosed only if Rheumatoid factor is positiveLife expectancy is unchanged  <response>: Small joints of hand feet and large joints like elbow, knee and ankle are involved.Women are affected 3 times more commonly than men. Older women 60 years are 6 times more commonly involved than younger one.A positive RA factor in the absence of other features is not sufficient evidence for RA.Life expectancy is shortened 3-7 years.Hepatosplenomegaly is not seen except in Feltys syndrome, where RA is associated with splenomegaly. 