<prompt> Baclofen acts as -GABAA receptor agonistGABAB receptor agonistGABAA receptor antagonistGABAB receptor antagonist  <response>: Ans. is b i.e., GABAB receptor agonist There are two types of GABA receptors. 1. GABAA receptor - Intrinsic ion channel -- increases Cl- conductance, blocked by bicuculline, facilatated by benzodiazepines. 2. GABAB receptor - G protein coupled receptor; hyperpolarizes neurones by increasing IC conductance and altering Ca flux, bicuculline has no effect, blocked by saclofen. o Baclofen acts as an agonist on GABAB receptor. 