<prompt> Enzyme that is responsible for unwinding of DNA is?LigaseDNA primaseHelicaseDNA polymerase  <response>: ANSWER: C HelicaseREF: Lippincotts biochemistry 3rd Ed page: 400PROTEINS INVOLVED IN REPLICATION:PROTEINFUNCTIONHelicaseCauses unwinding of DNA using ATPSSB Single strand binding proteinKeeps two strands separate , prevents renneiling of twostrandsTopisomerase I and IIThey have both nuclease strand cutting and ligase activity , hence they relieve torsional strain that results from helicase induced unwindingDNA primaseInitiates synthesis of RNA primerDNA polymeraseDeoxyribonucleotide polymerisationDNA ligase nick sealing enzymeSeals the single stranded nick between nascent chains and okazaki fragments 