<prompt> Familial hypercholesterolemia isDeficient LDL receptorsDeficient HDL receptorsHMG CoA reductase deficiencyDeficient VLDL receptors  <response>: Familial Hypercholesterolemia, or Type IIa hyperlipoproteinemia is defect in LDL-receptors or defect in Apo B100 apoprotein. In this disease, LDL levels cholesterol is raised in blood. It is Autosomal dominant AD. ADDITIONAL INFORMATION ON HYPERLIPOPROTEINEMIA: Type Defect Lipoprotein increased TGs Cholesterol Name I Lipoprotein Lipase or Apo C- II Chylomicron VLDL Normal Familial Hyperchylomicronemia AR IIa LDL - receptor or Apo B100 LDL Normal Familial Hypercholesterolemia IIb Unknown VLDL LDL Familial combined Hyperlipoproteinemia AR III Apo E Chylomicron Remanant VLDL remnant Dysbeta - lipoproteinemia or Broad - Beta disease AR 