<prompt> Maximum risk of invasive breast carcinoma is seen with?Complex FibroadenomaSclerosing AdenosisIntraductal papillomaAtypical ductal hyperplasia  <response>: ANSWER: D Atypical ductal hyperplasiaREF: Sabiston Textbook of Surgery, 18th ed Table 34-3, Schwartz 8til edition Table 17-4Annual risk for development of breast cancer in a woman with lobular carcinoma insitu LCIS is slightly less than 1 per year, and with either atypical ductal hyperplasia ADH or atypical lobular hyperplasia ALH it is between 0.5 and 1 per year NOTE: Annual risk and relative risk provided in the chart are differentCancer Risk Associated with Benign Breast Disorders and In Situ Carcinoma of the BreastNonproliferative lesions of the breastNo increased riskSclerosing adenosisNo increased riskIntraductal papillomaNo increased riskFlorid hyperplasia1.5 to 2-foldAtypical lobular hyperplasia4-foldAtypical ductal hyperplasia4-foldDuctal involvement by cells of atypical ductal hyperplasia7-foldLobular carcinoma in situ10-foldDuctal carcinoma in situ10-fold 