<prompt> Which of the following drug bind to tubulin and arrest metaphase of the cell cycle?VincristineCarmustineInfliximabMethotrexate  <response>: Vinca alkaloids, griseofulvin, taxanes, albendazole act on metaphase of cell cycleVinca alkaloids inhibit polymerization of microtubulesTaxanes inhibit depolymerization of microtubulesGoodman Gillman 12th ed. Pg 1705. 