<prompt> Drug has 40 absorption and hepatic extraction ratio of 0.6.what is bioavailabilit of the drug16202428  <response>: Ref Goodman and Gilman 12th20 If we administer 100 molecules of the drug. Amount absorbed 40 molecules 40 absorption Amount removed by liver - 40 x 0.6 Hepatic extraction ratio 24 molecules Drug available to produce action 40-24 16 molecules So, Bioavailability 16 percent 