<prompt> The investigation of choice in a 55-year-old post menopausal women who has presented with postmenopausal bleeding is :Pap smearFractional curettageTransvaginal ultrasoundCA-125  <response>: DC is required to rule out endometrial cancer. It is necessary in a woman complaining of menstrual disorder and postmenopausal bleeding Reference : Shaws Textbook of Gynaecology 16th edition, page no 399. 