<prompt> The treatment of single lesion paucibacillary leprosy isDapsone and rifampicinDapsone and clofazamine and ofloxacinRifampicin, ofloxacin and dapsoneRifampicin, ofloxacin and minocycline  <response>: ROM Regimen is used in single lesion leprosy.For patients with single-lesion paucibacillary leprosy, the WHO recommends a single dose of rifampin 600 mg, ofloxacin 400 mg, and minocycline 100 mg. Multibacillary adults should be treated with 100 mg of dapsone plus 50 mg of clofazimine daily unsupervised and with 600 mg of rifampin plus 300 mg of clofazimine monthlysupervised.Ref: Harrison 19th ed1127 