<prompt> True statement regarding development of drug resistance in MRSA is:Results due to penicillinase enzyme productionOccurs due to change in penicillin-binding proteinsChromosome mediatedTreated with amoxicillin clavulanic acid  <response>: Ans. B Occurs due to change in penicillin-binding proteinsRef: Katzungs 11e p776, KDT 8e p743Methicillin resistance occurs due to altered PBPs, thus no penicillin, infact no beta-lactam antibiotic is useful against methicillin-resistant Staphylococcus aureus MRSA infections. 