<prompt> Estrogen action on carbohydrate metabolismIncreases uptake of glucose through increase in insulin sensitivityGlycolysis increasesIncreasing central adipose depositionWorsening of NIDDM  <response>: Reduced estrogen may also lower metabolic rate, the rate at which the body conves stored energy into working energy. Its possible the same thing happens with women when estrogen levels drop after menopause. Some evidence suggests that estrogen hormone therapy increases a womans resting metabolic rate. Ref: guyton and hall textbook of medical physiology 12 edition page number:637,638,639 