<prompt> Which of the following is responsible for Bezold-Jarisch ReflexSerotoninHistamineProstaglandinAngiotensin  <response>: Ans. a SerotoninRef: Ganong, 25th edp.592, 662Bezold-Jarisch reflexIntracardiac injections of chemicals like serotonin, veratridine, capsaicin, phenylbiguanide activates this reflexAfferents for this reflex travel through unmyelinated vagal C fiber endingsThe reflex responses are:Apnea followed by rapid breathingHypotensionBradycardiaClinical importance of Bezold-Jarisch reflexThis reflex is responsible for sinus bradycardia seen during myocardial infarctionThis reflex is one of the causes for profound bradycardia and circulatory collapse after spinal anesthesia 