<prompt> Viral enterotoxin is detected as a possible of mechanism pathogenesis in -AdenovirusRotavirusCalcivirusAstrovirus  <response>: Ans. is b i.e., Rotavirus Pathogenesis Three different mechanisms have recognized 1. Destruction of mature enterocytes Major pathogenic mechanism Enterotoxin - A non-structural rotavirus protein, NSP4, functions as an enterotoxin and contributes to secretory diarrhea. Activation of enteric nervous system - Rotavirus may evoke fluid secretion through activation of enteric nervous system in the intestinal wall. 