<prompt> Which of the following statements about Acute Immune Thrombocytopenic Purpura is not true:Autoimmune MediatedMassive SplenomegalyIncreased Megakaryocytes in marrowIV immunoglobulins may be required  <response>: Answer is B Massive splenomegaly Immune Thrombocytopenic Purpura is not associated with massive splenomegaly Hepatomegaly, splenomegaly and lymphadenopathy are notably absent in ITP, and their presence should initiate an investigation for other possible underlying illnesses associated with thrombocytopenia- Oskis Essential Pediatrics 2d463 Acute ITP is considered a self limiting condition Immune Thrombocytopenic purpura is a self limiting condition and most children will have normal platelet count within 8-12 weeks even without treatment - Pediatrics: A concise Text by Kabro Srivastava r 164 Acute ITP in children frequently has a benign course with an excellent prognosis. More than 50 of untreated children with ITP recover within 4 weeks without treatment and more than 80 recover 6 months Intravenous immunoglobulins may be required for treatment of ITP Common Treatment Modalities for ITP Platelet count 20,000111 or significant mucosal bleeding Coicosteroids IV Immunoglobulins gamma globulins Additional Immunosupressive agents Rituximab Anti CD 20 Antibody Splenectomy Intravenous Immunoglohulin is a useful modality Jim- treatment of ITP 