<prompt> Treatment of choice for pleomorphic adenoma?EnucleationRadiotherapyExcision of tumor surgical removalRadical parotidectomy  <response>: Ans. c Excision of tumor surgical removal Ref. Bailey and Love Surgery 25thpg. 762PLEOMORPHIC ADENOMA Initially described as a mixed salivary gland tumor Accounts for 75 of parotid and 50 submandibular tumors Believed to have both epithelial and mesothelial elements Now appears to arise from ductal myoepithelial cells Slight female predominance known May undergo malignant change but risk is small Little is known about the origins of these neoplasms except that radiation exposure increases the risk. Equally uncertain is the histogenesis of the various components. A currently popular view is that all neoplastic elements, including those that appear mesenchymal, are of either myoepithelial or ductal reserve cell origin hence the designation pleomorphic adenoma. Requires excision with 5-10 mm margin as local implantation of cells can lead to recurrence. Treatment of choice for pleomorphic adenoma is superficial parotidectomy but, if the deep lobe of parotid is involved -Total parotidectomy is done. 