<prompt> First step in synthesis of eicosanoids is?Activation of lipooxygenaseActivation of PGH2 synthetaseActivation of hydrolaseNone  <response>: Eicosanoids synthesis is governed by the rate of release of arachidonic acid from membrane lipids in response to appropriate stimuli. These stimuli activate hydrolases, including phospholipase A , which conves arachidonic acid into Prostaglandins, thromboxanes by the COX pathway or Leukotrienes and lipoxins by the LOX pathway Reference: Harpers illustrated biochemistry 31st edition Page no 224 