<prompt> Thick mucous coat is -Protective in ulcer patientsNot protective in ulcer patientsEasily destroyed by antacidsCommonly associated with carcinomatous change  <response>: Ans. is a i.e., Protective in ulcer patientsSurface mucus layer acts as a defensive force and protects against peptic ulceration.Defensive forces include : Damaging forces include :I. Surface mucus 1. Gastric acidity Bicarbonate secretion into mucusMucosal blood flowApical surface membrane transpoEpithelial regereration capacityElaboration of prostaglandinsPeptic enzymesH. Pylori infectionNSAIDS, Aspirin, Cigarette, alcoholDuodenogastric refluxIshaemiaShockDelayed gastric emptying 