<prompt> A Case-Control Study is not characterized byDefinition of cases may be difficultAssessment of past exposure may be biasedIncidence rates may be computed directlyCases with the disease are compared to controls without the disease  <response>: We cannot measure the incidence and can only estimate the relative riskAdvantages of Case-Control StudiesThey are efficient for rare diseases or diseases with a long latency period between exposure and disease manifestation.They are less costly and less time-consuming; they are advantageous when exposure data is expensive or hard to obtain.They are advantageous when studying dynamic populations in which follow-up is difficult.Disadvantages of Case-Control StudiesThey are subject to selection bias.They are inefficient for rare exposures.Information on exposure is subject to observation bias.They generally do not allow calculation of incidence absolute risk.Park 23e pg: 74 