<prompt> AML with worst prognosis:821 translocationInversion 16Normal cytogeneticsMonosomy 7  <response>: PROGNOSIS OF AML: Good prognostic factors: t8;21 inv16 t15;17 CEBPA mutation NPM mutation Down syndrome Bad prognostic factors: Monosomy 7 5q deletion FLT3 - internal tandom duplication 