<prompt> A 1yearold child presented with a swelling in the left flank with episodes of flushing, diarrhea, sweating and bone pain. The diagnosis isNeuroblastomaWilms tumorMedulloblastomaPheochromocytoma  <response>: Clinical manifestations of neuroblastoma Because neuroblastoma arises from neural crest derivatives of sympathetic nervous system, it produces catecholamines.So, it may cause clinical feature due to : -- 1. Primary tumor 2. Metastais 3. Catecholamine secretion 