<prompt> Mechanism of action of aspirin as antiplatelet drug is its inhibitory action onProstacyclinsPGF-2 alphaThromboxane A2Phospholipase C  <response>: Refer KDT 7th 629 By inhibiting cyclooxygenase enzyme, aspirin initially decreses6 the level of both prostacyclins and TXA2 Howevr6 after some time prostacyclins synthesis resumes due to presence big nulcues in endothelium whereass TXA2 remain depressed because platelets are enucleated 