<prompt> Hydatiform mole -characterized histologically by:Hyaline membrane degenerationHydropic degeneration of the villous stromaNon-proliferation of cytotrophoblastsNon proliferation of syncytiotrophoblasts  <response>: Hydropic degeneration of the villous stroma 193, 197, 201-Duta 6thHvdatidiform mole vesicular mole - It is abnormal condition of placenta where there are partly degenerative partly proliferative changes in the young chorionic villi It is best regarded as a benign neoplasm of the chorion with malignant potential Vaginal bleeding is the commonest presentation 90 White currant in red currant juice Expulsion of grape like vesicles rich in HCG pe vaginum is diagnostic of vesicular mole. Histology shows hydropic degeneration of the villous stroma with absence of blood vessels and trophoblastic proliferation.RISK FACTORS FOR MALIGNANT CHANGE Patient above the age of 40 irrespective of parity Patients having previous 3 or more births irrespective of age is more important than the parity. Initial serum hCG 100,000 mIUml. Uterine size 20 weeks Previous history of molar pregnancy Large 6 cm theca-leutin cyst 