<prompt> After splenectomy, most common infection isPneumococcusEscherichia coliKlebsiellaStreptococcus  <response>: Streptococcus pneumoniae cause infection when host resistance is lowered by contributory factors such as respiratory viral infection, pulmonary congestion, stress, malnutrition, immunodeficiency and alcoholism. Splenectomy and sickle cell disease are impoant predisposing conditions. Reference: Textbook of Microbiology; Anathanarayan and panickers; 10th edition; Page no: 227 