<prompt> Boerhaave syndrome involves perforation of which part?Upper 13 esophagusMiddle 13 esophagusLower 13 esophagusFundus of stomach  <response>: Ans. is c i.e., Lower 13 esophagus Boerhaaves syndrome is spontaneous perforation of the esophagus, occuring usually due tosevere barotrauma when a person vomits against a closed glottis. The pressure in the esophagus rapidly increases and the esophagus bursts at its weakest point, sending a stream of material into the mediastinum and often the pleural cavity as well. Most common location of perforation is in the left posterolateral aspect 3-5 cm above the gastroesophageal junction. Second most common site of perforation is at the midthoracic esophagus on the right side. Most cases follow a bout of heavy eating and drinking. The principal early manifestation is pain felt in the chest and upper abdomen. 