<prompt> Granisetron, has antiemetic properties because of:Dopaminergic receptor blocking actionsGabamimetic actionsGaba-inhibitory actionsSerotonin receptor-blocking action  <response>: Granisetron is 5-HT3 antagonist and is 10 times more potent than ondansetron, and probably more effective during the repeat cycle of chemotherapy. The weak 5-HT4 blockade seen with ondansetron has not been detected in granisetron. lts plasma t12 is longer 8-12 hrs and it needs to be given only twice on the day of chemotherapy. 