<prompt> For treatment of cerebral edema due to brain tumor, the corticosteroid used by preference is?HydrocortisonePrednisoloneDexamethasoneTriamcinolone  <response>: Ans. c Dexamethasone Ref. KDT, Pharmacology, 6th ed., 285. Dexamethasone: Very potent and highly selective glucocorticoid. Long acting, causes marked pituitary-adrenal suppression, but fluid retention and hypertension are not a problem. It is used for inflammatory and allergic conditions 0.5-5 mgday oraL Shock, cerebral edema, etc. 4-20 mgday i.v. infusion or i.m. injection. Also used topically.Educational Points: Most potent glucocorticoidBeta Dexamethasone Maximum glucocorticoid activityDexamethasone Glucocorticoid having max mineralocorticoid activityHydrocortisone Selective Mineralocorticoid actionDOCA Most potent MineralocorticoidAldosterone CompoundGlucoMineralGLUCOCORTICOIDSShort acting, Biological t- 12hr1. Hydrocortisone cortisol11Intermediate acting,Biological t-12-36 hr2. Prednisolone40.83. Methyl- prednisolone50.54. Triamcinolone50Long acting,Biological t- 36 hr5. Dexamethasone2506. Betamethasone250MINERALO- CORTICOIDS 7. Desoxy- corticosterone scetate DOCA01008. Fludrocortisone101509. Aldosterone0.33000 