<prompt> Cherry red spot in retina is a feature of:Infantile Gauchers diseaseNiemann Pick diseaseFabrys diseaseCRVO  <response>: Ans: B Niemann Pick disease Ref: Kanski 7th edition Clinical ophthalmology,, pg no 683-684Explanation:Causes of cherry red spot:Central retinal artery occlusionBlunt injury - Berlins edeme or commotion retinaeQuinine toxicityMacular holeGangliosidosisMucolipidosisTay Sachs diseaseSandhoff diseaseNiemann Pick diseaseFaber diseaseMechanism of Cherry red spotThe fovea is the thinnest part of the retina is devoid of ganglion cell layer.The following mechanisms causes cherry red spotWhen the retina becomes opaque due to edema CRAOInjury to the photoreceptors Commotion retinaDue to intracellular accumulation of glvcolipids phospholipids in the ganglion cellThe fovea remains transparent transmits the underlying choroid.This appears as cherry red spot. 