<prompt> The parenteral administration of streptokinaseincreases the formation of plasminogenis less effective following a myocardial infarct than t-pAcauses a high incidence of thrombocytopeniamay cause bleeding reversible by aminocaproic acid  <response>: Streptokinase SK is thrombolytic or fibrinolytic because it activates plasminogen, resulting in the increased formation of plasmin. Its efficacy is equivalent to that of tissue plasminogen activator t-PA, but SK is not clot-specific. All thrombolytics can cause bleeding, which may be counteracted to some extent by administration of antifibrinolysins, such as aminocaproic acid. 