<prompt> Best treatment strategy for carcinoma anal canal:ChemoradiationSurgeryRadiationChemotherapy  <response>: Nowadays the primary treatment of choice is chemoradiotherapy Combined modality therapy CMT; Nigro Regimen, which usually includes 5-FU, Mitomycin-C and cisplatin Radical surgery is indicated in those with persistent or recurrent disease following CMT or Nigro Regimen. 