<prompt> Which of the following drug crosses placentaHeparinWarfarinDicumarolNicoumalone  <response>: Warfarin 601-KDT6th WARFARIN - It crosses placenta and is secreted in milk however quantity of active form is generally insufficient to affect the suckling infants HEPARIN - does not cross BBB or placenta- It is the anticoagulant of choice during pregnancy Bleeding due to overdose is the most serious complication of heparin therapy other side effects are thrombocytopenia, alopecia, osteoporosis, hypersensitivity reactions. 