<prompt> Which of the following statements about Rheumatoid Factor is true ?It is an IgM antibody directed against IgGIt is an IgG antibody directed against 1gMIt is more specific than Anti-CCP antibodiesIt is positive in all cases of Juvenile Rheumatoid Ahritis  <response>: In rheumatoid ahritis it is suspected that antibodies plays a role in the disease. About80 of patients have serun IgM autoantibodies that bind to fc poion of their own self IgG. These antibodies are called rheumatoid factor. Ref :Robbins basic pathology 9th edition page no 784,green boxPathogenesis 