<prompt> Omalizumab isInterleukin 2 receptor blockerAnti IgE antibodyAnti IgM antibodyLeukotriene receptor blocker  <response>: ANTI-IgE ANTIBODY Omalizumab It is a humanized monoclonal antibody against IgE. Administered s.c., Mech of action:- It neutralizes free IgE in circulation without activating mast cells and other inflammatory cells. On antigen challenge, little IgE is available bound to the mast cell surface receptors FceR1 to trigger mediator release and cause bronchoconstriction. In severe extrinsic asthma, omalizumab has been found to reduce exacerbations and steroid requirement. No benefit has been noted in nonallergic asthma. Ref:- kd tripathi; pg num:-231 