<prompt> Tadalafil is contraindicated in?Pulmonary aery hypeensionChronic stable angina acute episodeActive infectionsHepatic dysfunction  <response>: Tadalafil is CI with NTG which is taken for acute attack of angina as in this case. Tadalafil- Uses: For erectile dysfunction For symptoms of BPH Nitrates should not be used within 24 hours of sildenafil, tadalafil, or vardenafil may produce severe hypotension Nitrates- CI in the presence of hyperophic CMP or severe Aoic Stenosis MC side effect of nitrate treatment is headache Hypotension may occur in hypovolemic patients. Development of tolerance To avoid nitrate tolerance, a daily 8 to 12 hour interval free of nitrate exposure is recommended 