<prompt> MDR TB is defined as-Resistance to INH and EthambutolResistance to Rifampicin and EthambutolResistance to Pyrazinamide and RifampicinResistance to INH and Rifampicin  <response>: Ans. is d i.e., Resistance to INH and Rifampicin Treatment of multidrug resistance MDR TBo MDR-TB is defined as resistance to at least both INH and rifampicin. Previously it was classified as Category IV under DOTS DOTS-PLUS.o The treatment is given in two phases, the intestive phase IP and the continuation phase CP. The total duration of treatment for regimen for MDR-TB is 24-27 months, depending on the IP duration,o Treatment regimen comprises :-Intensive phase 6-9 months : Six drugs : Kanamycin Km, levofloxacin Lvx, ethionamide Eto, pyrazinamide Z, ethambuto! E, and cycloserine Cs.Continuation phase 18 months: Four drugs : Levofloxaxcin, ethionamide, ethambuto! and cycloserine,o Total duration of treatment is 24-27 months.Treatment of extensive drug resistance XDR TBo XDR-TB is defined as resistance to any fluoroquinolone and at least one of the following three second-line drugs capreomycin, kanamycin, amikacin, in addition to multidrug resistance,o The Regimen for XDR-TB would be of 24-30 months duration, with 6-12 months Intensive Phase IP and 18 months Continuation Phase CP,o Regimen is :-intensive phase 6-12 months : Seven drugs : Capreomycin, PAS. moxifloxacin, high dose INH, clofazimine, Linezolid, amoxyclav.Continuation phase 18 months : Six drugs : PAS, moxifloxacin, high dose INH, clofazimine, linezolid, amoxyclav. 