<prompt> Which anticancer drug prevents spindle formation?BusulfanVinca alkaloids5 - FUMethotrexate  <response>: Ans. is b i.e., Vinca alkaloids Taxanes Paclitaxel and Docetaxel enhances polymerization of tubulin a mechanism opposite to that of vincaalkaloids -the microtubules are stabilized and their depolymerization is prevented. Vinca alkaloids vincristine, vinblastineprevent polymerization and assembly of microtubules. Mitotic inhibitors Enhances polymerization Preventpolymerization Taxanes Vinca alkaloids 