<prompt> A major source of Von Willebrand factor vWFErythrocytesNeutrophilsEndothelial cellsMonocytes  <response>: Circulating factor VIII has two components.a Factor VIIIc Procoagulant proteinThis is the smaller componentIt is synthesized in the liver main source and kidney.It is an intrinsic pathway component required for activation of factor X.b Von Willebrand factor vWFThis is the larger component.It is produced by endothelial cells main source and megakaryocytes.It has two major functions -Helps in platelets adhesion by interacting platelet membrane glycoprotein Ib-IX.Stabilizes factor VIIIc. 