<prompt> High incidence of oral malignancies is attributed toUse of panPoor hygieneHigh incidence of HPVPoor nutrition  <response>: In the Indian subcontinent, the use of pan a combination of betel nut, areca nut, lime and tobacco, as well as reverse smoking smoking a cheroot with the burning end inside the mouth, are responsible for the high incidence of oral cancer. Betel quid appears to be the major carcinogen, although there is also a relationship between slaked lime and the areca nut and cancer.Ref: Bailey and love pg: 760 