<prompt> Enlarged and pale placenta, is due to infection by ___ParvovirusMeaslesSyphilisToxoplasmosis  <response>: Enlarged and pale placenta is due to infection by syphilis. Other clinical manifestations and complications include: Spontaneous aboion Stillbih Non-immune hydrops intrauterine Growth restriction Perinatal death Ref: Williams Obstetrics 25th edition Pgno: 1237 