<prompt> Genetic studies of a patient is positive for products of mic-2 gene. He may have the following condition:Ewings sarcomaOsteosarcomaDermatofibroma protuberans D. Alveolar cell sarcomaAlveolar cell sarcoma  <response>: The presence of p3032, the product of the mic-2 gene which maps to the pseudoautosomal region of the X and Y chromosomes is a cell-surface marker for Ewings sarcoma and other members of the Ewings family of tumors, sometimes called PNETs. Glycogen-filled cytoplasm detected by staining with periodic acid-Schiff is also characteristic of Ewings sarcoma cells. The classic cytogenetic abnormality associated with this disease and other PNETs is a reciprocal translocation of the long arms of chromosomes 11 and 22, t11;22, which creates a chimeric gene product of unknown function with components from the fli-1 gene on chromosome 11 and ews on 22. Ref: Patel S.R., Benjamin R.S. 2012. Chapter 98. Soft Tissue and Bone Sarcomas and Bone Metastases. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo Eds, Harrisons Principles of Internal Medicine, 18e. 