<prompt> Which of the following antihistaminic is free of arrhythmogenic potential?TerfenadineFexofenadineLoratadineEbastine  <response>: Loratidine Loratidine is paially metabolized by CYP3A4 to an active metabolite with a longer T12 of 17 hours but in contrast to terfenadineastemizole, it has not produced cardiac arrhythmia in overdose. 