<prompt> A six-year-old child is admitted to the Paediatric ICU for seizures. He has been on treatment with Tacrolimus and Prednisolone. On investigations his blood urea is 68 mgdl, Serum Sodium is 136 meql likely cause of his seizuresUremiaHyponatremiaHypocalcemiaTacrolimus Toxity  <response>: Tacrolimus neurotoxicity is an established cause for seizures and the most likely reason for seizures in this child.In hyponatremia, seizures usually develop when sodium levels decrease below 125 meqL.In hypocalcaemia, seizures develop when calcium level is below 6 mgdl.Uremic seizures occur late after delirium, hallucinations and agitation. 