<prompt> Poal Acinus meansThe space between two central veins of adjacent lobulesThe space between two hepatic ductsThe space between central vein and bile ductThe space between Poal vein and central vein  <response>: The hepatic or poal acinus is the functional unit of the liver.The acinus consists of an irregular shaped, roughly ellipsoidal mass of hepatocytes aligned around the hepatic aerioles and poal venules just as they anastomose into sinusoids.The acinus is roughly divided into zones that correspond to distance from the aerial blood supply - those hepatocytes closest to the aerioles zone 1 below are the best oxygenated, while those fahest from the aerioles have the poorest supply of oxygen. This arrangement also means that cells in the center of the acinus again, zone 1 are the first to see and potentially absorb blood-borne toxins absorbed into the poal blood from the small intestine.Reference: Krishna Garg Histology; 5th edition; Page no: 171 