<prompt> In Wilms tumor the following leads to emergence of resistance to chromotherapyNehprogenic restsMonoblastic morphologyAnpalsiaCapsular infiltration  <response>: 5 percnt of tumors have Anpalsia, defined as the presence of cells with large hyperchromatic pleomprphic nuclei and abnormal mitosis and the presrnc of anapladsia coreltes with p53 mutation 