<prompt> In Unconjugated hyperbilirubinemia, the risk of kernicterus increases with the use ofCeftriaxonePhenobarbitoneAmpicillinSulphonamide  <response>: Sulfonamides also called sulfa drugs are a group of antibiotics that kill bacteria. Sulfonamides may unbind bilirubin from albumin, which increases blood levels of bilirubin. The unbound bilirubin can cross into the brain and cause kernicterus. Reference: GHAI Essential pediatrics, 8th edition 