<prompt> Simian crease is seen in:Downs syndromeTrisomy of chromosome No.13Cri-du-chat syndromeAll of the above  <response>: Simian crease is an older name for a condition now more commonly called single transverse palmar crease. It refers to a single crease across the palm of the hand. In most individuals, there are two slightly offset creases across the palm. Simian crease is seen in:Downs syndromeTrisomy of chromosome No.13 Cri-du-chat syndrome 