<prompt> Which of the following is a poor prognostic factor in Acute Lymphoblastic Leukemia ALL -Hyperdiploidyt 9;22; t 4; 112-8 years of ageWBC count 50,000  <response>: The high risk indicators in ALL includes age below 1 year above 10 year, male ,initial white cell count more than 50,000mm3, massive hepatomegaly splenomegaly, prwsence of mediastinal mass central nervous system leukaemia , mature Bcell as phenotype , hypodiploidy, t9;22,t4;11, t8;14.Reference :Ghai essential pediatrics 8th edition pg no 601. 