<prompt> An aminoglycoside with an outstanding feature of being little or not affected by majority of inacti vating enzymes is-GentamycinTobramycinAmikacinSisomycin  <response>: Ans. is c i.e., Amikacin Amikacin has widest spectrum of activity amongst aminoglycosides as it has resistance to bacterial aminoglycoside inactivating enzymes. 