<prompt> Somatic mutation E17K in the PH domain of AKT-1 gene mutation is associated with?StomachBreastOvaryPancreas  <response>: Ans. b BreastRef: Atlasgeneticsoncology.orgGenesAKT1Hyper-activation of AKT1 has been found associated to several human cancers:Thyroid carcinomaBreast carcinomaNon-small cell lung carcinomaGastric carcinomaNow coming to question: Somatic mutation E17K occurs in the PH domain of AKT1 in 8 of human breast cancers. This mutation also occurs in 6 of colorectal cancers. 