<prompt> Which of the following is NOT a cause of congenital hypercoagulability aEURProtein C deficiencyProtein S deficiencyAntiphospholipid antibody syndromeMTHFR gene mutations  <response>: Antiphospholipid antibody syndrome Congenital Factor V Leiden 5 of the population are heterozygous for FVL. Prothrombin mutation G20210A, 5UTR. High homocysteine levels due to MTHFR mutation Sickle-cell disease only small risk Antithrombin III deficiency. Protein C deficiency. Protein S deficiency. Plasminogen and fibrinolysis disorders very rare Acquired Antiphospholipid antibodies - Anti-cardiolipin antibodies andor - Lupus anticoagulants Heparin-induced thrombocytopenia Paroxysmal nocturnal hemoglobinuria Nephrotic syndrome Hyperestrogenemia Estrogen-containing honnonal contraceptives Tobacco smoking Hyperhomocysteinemia due to vitamin B12 and folic acid deficiency 