<prompt> Binding of oxygen to haemoglobin reduces its affinity for carbon dioxide, which is known asHaldane effectChloride shiftBohr effectAnion exchanger 1  <response>: Increase in carbon dioxide in the blood causes oxygento be displaced from the hemoglobin the Bohr effect. The reverse is also true: binding of oxygen with hemoglobin tends to displace carbon dioxidefrom the blood. Indeed, this effect, called the Haldane effect, Ref: Guyton Hall: Textbook of Medical Physiology page no:946 