<prompt> Which of the following enzymes contain manganese as its cofactor?LDHArginaseHexokinaseDNA polymerase  <response>: Manganese: Cofactor for enzymes, e.g., arginase, pyruvate carboxylase.Enzymes that require a metal ion cofactor are termed metal-activated enzymes to distinguish them from the metalloenzymes for which bound metal ions serve as prosthetic groups.Reference-Satyanarayana Pg- 405 