<prompt> Dissociate anaesthesia is seen with?PropofolKetamineThiopentalHalothane  <response>: Ans. b Ketamine. Ref: KD Tripathi, Pharmacology 4th, ed., 353KETAMINE -Sensitizes heart to effects of adrenaline -Increases IOT and ICT and intrauterine pressure -No muscle relaxation, analgesia -Bronchodilator -Has antiepileptic action -May cause delirium tremens -Induces so-called dissociative anaesthesia -Profound analgesia, immobility, amnesia, with light sleep and feeling of dissociation from ones own body and the surroundings. -Heart rate, cardiac output and BP are elevated due to sympathetic stimulation. -It has been recommended in head and neck, patients who have bleed, asthmatics and for short operations. -It is good for repeated use; burn dressing, angiographies, cardiac catheterization and trauma surgery. -Dangerous for hypertensives and in ischaemic. -Drug of choice in paediatric, bum, porphyria patients and useful in elderly. 