<prompt> Cullens issign are seen:PeritonitisChronic pancreatitisPancreatic cancerAcute pancreatitis  <response>: Ans: D Acute pancreatitis Bleeding into the fascial planes can prod uce bl uish discolouration of the flanks Grey Turners sign or umbilicus Cullens sign. Neither sign is pathognomonic of acute pancreatitis; Cullens sign was first described in association with rupture of an ectopic pregnancy. Subcutaneous fat necrosis may produce small, red, tender nodules on the skin of the legs- LB 26th1128 