<prompt> Metabolism of a drug primarily results inActivation of the active drugConversion of prodruv to active metaboliteConversion of lipid soluble drugs to water soluble metabolitesConversion of water soluble drugs to lipid solible metabolites  <response>: Ref-Katzung 10e p50 After metabolism most of the drugs become inactive and their excreted through the kidney. Lipids soluble drugs wil be reabsprbed whereas water soluble drugs are easily excreted.thus, metabolism of drugs helps in the conversion of liquid soluble drugs to water soluble metabolites 