<prompt> Drug of choice for relapsing remitting multiple sclerosis is:Alpha IENBeta IFNGamma IFNNatalizumab  <response>: Answer is option 2,beta interferon Early treatment with high-dose interferon beta-1a reverses cognitive and coical plasticity deficits in multiple sclerosis. Mori F1, Kusayanagi H, Buttari F, Centini B, Monteleone F, Nicoletti CG, Bernardi G, Di Cantogno EV, Marciani MG, Centonze D. Author information Abstract Acute inflammation is associated with cognitive deficits and alterations of coical plasticity in multiple sclerosis MS. We tested whether early treatment with high-dose interferon IFN beta-1a, known to reduce inflammatory activity, improves coical function and cognitive deficits in MS. 