<prompt> Patient with growth retardation, delayed milestones with kinky hair. What is the diagnosis?Menkes diseaseTrisomy 21Lesch nyhan syndromeWilson disease  <response>: The given scenario suggests diagnosis of Menkes disease X- linked recessive disorder caused by mutations in genes coding for the copper transpo protein ATP7A. CF- Growth retardation Delayed milestones Kinky hair Hypotonia, hypothermia Seizures Lesch nyhan syndrome- self injury Wilson disease- KF ring, neurological hepatic manisfestation. 