<prompt> In pemphigus circulating antibodies attack:Desmoglein 12.Desmoglein13.Desmoglein14.Desmoglein24.  <response>: PemphigusIs a skin and mucous membrane disease with autoimmune etiology.Characterized histologically by intradermal blisters circulating IgG IgG1 and IgG4 antibody against keratinocyte cell surface attack Desmoglein 1 and 3. 