<prompt> Mutation in NPHS 1 gene causes which disease?Alport syndromeCongenital Finnish type nephrotic syndromeFocal segmental glomerulonephritisNail patella syndrome  <response>: Ans. b Congenital Finnish type nephrotic syndromeRef: Nelson 18th ed. Table 527.1 CNF is one of the Finnish heritage diseases and rare form of nephrotic syndrome. It occurs predominantly in families of Finnish origin and manifests shortly after birth The condition is caused by a defect in the protein nephrin, which is found in the kidney. Gene responsible is NPHSL. 