<prompt> Mark the true and false statement about brain tumors: 1. Most common primary brain tumor is astrocytoma 2. Radiation exposure genetic abnormalities are the risk factors 3. MEN-2 and NF-1 increases the risk 4. Three cardinal symptoms are seizures, raised ICT focal neurological deficit 5. Dexamethasone reduces peritumoral edema 6. Primary goals of surgery includes histologic diagnosis reduction of mass effect 7. Anti-epileptics for tumors close to sensorimotor strip 8. Craniospinal irradiation for tumors associated with CSF spread1-T, 2-T, 3-T, 4-T, 5-T, 6-T, 7-F, 8-T1-T, 2-T, 3-F, 4-T, 5-T, 6-T, 7-T, 8-T1-F, 2-T, 3-F, 4-T, 5-T, 6-T, 7-T, 8-T1-T, 2-F, 3-T, 4-T, 5-F, 6-T, 7-T, 8-T  <response>: - MC primary brain tumor - Meningioma 35 glial tumorQ30 - MC brain tumor - Metastasis - MC malignant BT of childhood - Most radiosensitive BT - Medulloblastoma - BT associated with calcification COM - Craniopharyngiomamost ODGQ90 Meningioma20-25 BRAIN TUMOR - Most brain tumors occur sporadically - Radiation exposuregenetic abnormalities are the risk factors Genetic abnormalities with brain tumors RL not in MTV GT - Retinoblastoma - Li-Fraumeni - NF-1 2 - MEN 1 - Turcots syndrome - VHL syndrome - Gorlin syndrome - Tuberous sclerosis Clinical Features - Three cardinal symptoms: Seizures, Raised ICT focal neurological deficitFND - Raised ICT leads to headache worse in morning straining, associated with nausea vomiting - FND: Progressive over time, characteristic of location - Pituitary adenoma may also present with endocrine abnormalities Diagnosis - IOC for diagnosis: MRI Treatment - Dexamethasone: Reduces peitumoral edema - Anti-epileptics: For tumors close to sensorimotor strip - Mannitol: Adminstered before dural opening operative resection - Surgery: Primary goals of surgery includes histologic diagnosis reduction of mass effect preservation of neurological function - Radiotherapy: In case of positive margins tumor infiltrating surrounding brain - Craniospinal irradiation: For tumors associated with CSF Spread 