<prompt> True about rectal CaMC type adenocarcinomaSurgery is the treatment of choiceSurgical treatment indicated inspite of hepatic metastasisAPR done in lesions of upper zone  <response>: Although rare, the incidence of anal squamous cell carcinoma SCC is rising, with a direct association with HPV infection, AIN and immunosuppression. Thus, high-risk groups are those infected with HPV especially subtypes 16, 18, 31 or 33 Ref: Bailey Love;s Sho Practice of Surgery,E25,Page-1269 