<prompt> Prostaglandin inhibiting action of aspirin is useful in the treatment of all of the following conditions except-Analgesia and antipyresisClosure of ductus aeriosusUricosuriaAntiinflammatory and antiplatelet aggregation  <response>: Ans. is c i.e., Uricosuria o At higher doses, aspirin has uricosuric action: 2 gmday : urate retention 2-5 gmday : No change 5 gmday : T urate excretion uricosuric action o This uricosuric action is unrelated to action of aspirin on PG synthesis inhibition. o Analgesic, anti-inflammatory, antipyretic and antiplatelet aggregatory actions of aspirin are due to inhibition of PG synthesis. o This action is also responsible of closure of PDA. 