<prompt> Which part of bacteria is most antigenic-Protein coatLipopolysaccharideNucleic acidLipids  <response>: Proteins are most immunogenic, while lipids nucleic acids arc least immunogenic.Polysaccharides carbohydrates are less immunogenic than protein antigens, but are more antigenic than lipids nucleic acids. Determinants of antigenicityA number of properties of antigen determine its antigenicity production of antibody or induction of cell mediated immunity: Chemical natureProteins Polysaccharide lipids and nucleic acids.All proteins except gelatin arc immunogenic. SizeHigh molecular weight particles low molecular weight particles. Foreign nessIn general, molecules recognized as self are not immunogenic; for immunogenicity, molecules must be recognized as nonself. Susceptibility to tissue enzymesOnly substances which are metabolized and are susceptible to the action of tissue enzymes behave as antigens. Route of administrationParenteral oral 