<prompt> Side effects of phenytoin are all EXCEPTGum hypertrophyHirsutismMicrocytic anemiaOsteomalacia  <response>: C Microcytic anemia At therapeutic levels: Gum hypertrophy: Commonest 20 incidence, more in younger patients, can be minimized by maintaining oral hygiene. Hirsutism, coarsening of facial features troublesome in young girls, aerie. Hypersensitivity reactions are--rashes, DLE, lymphadenopathy; neutropenia is rare but requires discontinuation of therapy. Megaloblastic anaemia: Phenytoin decreases folate absorption and increases its excretion. Osteomalacia: Phenytoin desensitizes target tissues to vitamin D and interferes with calcium metabolism. It can inhibit insulin release and cause hyperglycaemia. Used during pregnancy--can produce foetal hydantoin syndrome hypoplastic phalanges, cleft palate, hare lip, microcephaly, which is probably caused by its areneoxide metabolite. 