<prompt> Which of the following does not predispose to leukemia?Genetic disorderAlcoholSmokingChemical exposure  <response>: Ans. is b i.e., Alcohol Leukemia risk factors1 Generala Gender: Men are more likely to develop CML, CLL and AML than women.b Age: The risk of most leukemias, with the exception of ALL, typically increases with age.2 Geneticsa Family history: First degree relatives of CLL patients, or having an identical twin who has or had AML or ALL, increases the risk for developing the disease.b Genetic diseases: AML has been associated with Down syndrome, Klinefelter syndrome, Patau syndrome, Fanconi anemia, Bloom syndrome, Ataxia telangiectasia, and Kostman syndrome, may play a role in the development of leukemia.3 Smoking: Smoking cigarettes does increase the risk of developing AML.4 Exposuresa Radiation: Exposure to high-energy radiation e.g., atomic bomb explosions and intense exposure to low- energy radiation from electromagnetic fields e.g., power lines.b Chemical exposure: Long-term exposure to chemicals like benzene ethylene oxide is considered to be a risk for leukemia.c Drugs - alkylating agents topoisomerase II inhibitors increase the risk of AML.5 Previous Cancer Treatment: Certain types of chemotherapy and radiation therapy for other cancers are considered leukemia risk factors. 