<prompt> Ram Devi presented with generalized edema sweating and flushing tachycardia and fever after bee sting. This is -T cell mediated cytotoxicityIgE mediated reactionIgG mediated reactionIgA mediated hypersensitivity reaction  <response>: Ans. is b i.e., IgE mediated reaction o The symptoms of the patient are dt hypersensitivity type I reaction Type I is mediated by IgE and it flairs up within minutes. o There are typical features of anaphylaxis systemic Type I hypersensitivity. Clinical manifestations of anaphylaxis o Flushing and tachycardia are usually the first and are invariant symptoms of anaphylaxis. o Uicaria pruritis o Angiodema o Respiratory distress and wheezing due to bronchoconstriction. o Confusion and alteration of mental status can occur. 