<prompt> DyskeratosisLeukoplakiaHyperpigmentationNail dystrophyPremature keratinisation  <response>: dyskeratosis disker-a-tosis, 1. Premature keratinization in individual epithelial cells that have not reached the keratinizing surface layer; dyskeratotic cells generally become rounded and they may break away from adjacent cells and fall off. Dyskeratosis terms that abnormal premature keratinisation within cells below the stratum granulosum. Ref: Robbins and cotrans 9e Pg 1143 