<prompt> Rhinosporidiosis is caused byHPVR. seeberiKlebsiella rhinoscleromatisEBV  <response>: Rhinosporidiosis is a chronic granulomatous infection of the mucous membrane.The ecological agent is Rhinosporidium seeberi.Rhinosporidium seeberi is an aquatic bacterium not a fungus. Infection usually results from a local trauma inoculation with the organism.It is seen in India, Pakistan and Sri Lanka. In India, most of the cases are seen in Southern states.Infection of the nose and nasopharynx is observed in 70 of persons with rhinosporidiosis; infection of the palpebral conjunctiva or associated structures including lacrimal apparatus is observed in 15 of cases.Other structures of the mouth and upper airway may be sites of disease. Disease of the skin, ear, genitals and rectum has also been described.Rhinosporidiosis is an infection that typically limited to the mucosal epithelium.The disease progress with local replication of R. seeberi and associated hyperplastic growth of host tissue and a localized immune response.Clinical features of RhinosporidiosisRhinosporidiosis presents as soft leafy polypoidal mass soft polyp, which is pink to purple in colour studded with white dots, i.e., strawberry appearance. This appearance results from sporangia, which is visible as grey or yellow spots in the vascular polypoid masses.Because the polyps are vascular and friable, they bleed easily upon manipulation. Treatment - The treatment of choice is surgical excision.Complete excision of mass is done with diathermy knife and cauterization of the base. Dapsone is being tried for treating rhinosporidiosis but with limited success. 