<prompt> All of the following are true about Irinotecan exceptIt is a Topo-isomerase II inhibitorIt is excreted though liverIt is used for colorectal cancerIt can cause diarrhoea because of cholinergic property  <response>: Irinotecan Topotecan are Topoisomerase-I inhibitors.Etoposide Teniposide are Topoisomerase-II inhibitors. 