<prompt> Which of the following is associated with cystic disease in kidney?FibrocystinPolycystin-1Polycystin-2All of the above  <response>: Autosomal dominant polycystic kidney disease is caused by mutations in: The PKD1 gene encodes a large 460-kD integral membrane protein named polycystin-1 The PKD2 gene product polycystin-2 Autosomal recessive kidney disease is caused due to mutation in PKHD1 gene coding for fibrocystin. Ref: Robbins 8th edition Chapter 20. 