<prompt> A genetic disorder renders fructose 1, 6biphosphatase in liver less sensitive to regulation by fructose 2, 6biphosphate. All of the following metabolic changes are observed in this disorder exceptLevel of fructose 1, 6biphosphate is higher than normalLevel of fructose 1, 6biphosphate is lower than normalLess pyruvate is formedLess ATP is generated  <response>: Level of fructose 1, 6-biphosphate is higher than normalFructose-1, 6-bisphosphatase is inhibited by fructose-2, 6-bisphosphate.If fructose-1, 6-bisphosphatase becomes less sensitive to inhibition caused by fructose-2, 6-bisphosphate, its activity will increase and there will be increased conversion of fructose-1, 6-bisphosphate into fructose-6-phosphate reaction catalyzed by fructose-1, 6-bisphosphatase.Thus, level of fructose-1, 6-bisphosphate will decrease.Fructose-1, 6-bisphosphatase is a regulating enzyme for gluconeogenesis, and therefore gluconeogenesis will increase.As the cycle will shift more toward gluconeogenesis, glycolysis will decrease with a resultant decrease in production of ATP and pyruvate. 