<prompt> Which of the following is not a protein misfolding disorder?TuberculosisCreutzfeldt Jakob diseaseAlzheimers diseaseCystic fibrosis  <response>: Ans. A. TuberculosisTuberculosis is not a disorder of protein misfoldingProtein Misfolding Disordersa. Protein misfolding disorders, also known as proteopathies are conditions in which some proteins become structurally abnormal and impair the function of cells and tissues.b. Protein folding is abnormal and they fail to perform normally and may even gain toxic effects.c. e.g. Alzheimers disease beta amyloid peptide, Creutzfeldt Jakob disease prion disease, Cystic fibrosis CFTR. 