<prompt> Co factor of glutathione peroxidase -SeleniumMagnesiumManganeseZinc  <response>: Ans. is a i.e., Selenium Keshans disease is a form of cardiomyopathy and is characterized by multifocal myocardial necrosis, cardiac arrhythmias and cardiac enlargement. It is prevalent in the Keshan province of China, soil of which is deficient in Selenium. Selenium deficiency in the soil is found to cause an increased prevalence of highly cirulent coxsackie B virus. Hence selenium deficiency and the superimposed Coxsackie B virus is found to precipitate Keshans disease. Treatment is selenium and Vitamin E supplementation 