<prompt> All of the following are true regarding hemolytic anemia except: March 2008 and 2011, March 2013Raised haptoglobin levelsRaised unconjugated bilirubinReticulocytosisHemosiderinuria indicates intravascular hemolysis  <response>: Ans. A: Raised haptoglobin levelsIn hemolytic anemia, the level of unconjugated bilirubin in the blood is elevated. This may lead to jaundice. The level of lactate dehydrogenase LDH in the blood is elevatedHaptoglobin levels are decreasedIf the direct Coombs test is positive, hemolysis is caused by an immune process.Hemosiderin in the urine indicates chronic intravascular hemolysis.There is also urobilinogen in the urine. Peripheral blood smear microscopy:Fragments of the red blood cells schistocytes can be presentSome red blood cells may appear smaller and rounder than usual spherocytesReticulocytes are present in elevated numbers. 