<prompt> 1718. A patient presents with increased serum ferritin, decreased TIBC, increased serum iron, saturation increased. Most probable diagnosis is -Anemia of chronic diseaseSideroblastic anemiaIron deficiency anemiaThalassemia minor  <response>: In the given case,serum iron is raised,which implies that it is not a iron deficiency anemia or anemia of chronic disorderwhere serum iron is reduced In sideroblastic anemia , serum ferritin levels are raised,marrow iron stores are raised,serum iron is usually raised with almost complete saturation of TIBC. The disorder has its pathogenesis in disturbed growth maturation of erythroid precursors at the level of hematopoietic stem cell,probably due to reduced activity of the enzyme,ALA synthetase. Reference :Harsh mohan textbook of pathology sixth edition pg no 300. 