<prompt> Waldenstroms macroglobulinemia is seen inNHLPlasmocytic LymphomaCLLNone  <response>: Waldenstrom Macroglobulinemia B cell neoplasm in 6th or 7th decade of life similar to CLLSLE and multiple myelomaGenetics - Deletion of chromosome 6qNeoplastic infiltrates into organs like spleen, lymph node bone marrowBalanced production of light and heavy chains thereby decreasing the development of renal failure or amyloidosisBlood - anemia, atypical plasmacytoid lymphocytes, ESR, rouleaux formation Immunoelectrophoresis - Presence of M or monoclonal spikeBone marrow - plasmacytoid infiltrates, PAS inclusions, Russell bodies cytoplasmic Ig, Dutcher bodies nuclear Ig Immunophenotyping - CD 20 , CD 5- and CD 10-Refer: Robbins Cotrans - Pathologic Basis of Disease, SAE, 1st edition, Vol I-pg no: 598-599 