<prompt> Antibody in Goodpasture syndrome:Lupus anticoagulantAnti-GBM antibodyAnti-Ro antibodyAnti- mitochondrial antibody  <response>: Ans. b Anti GBM antibodyRef.: Harrison 18th edition, Chapter 283 Patients who develop autoantibodies directed against glomerular basement antigens frequently develop a glomerulonephritis termed antiglomerular basement membrane anti-GBM disease. When they present with lung hemorrhage and glomerulonephritis, they have a pulmonary-renal syndrome called Goodpastures syndrome. Goods syndrome is a Thymoma with immunodeficiency It is a cause of combined B and T cell immunodeficiency in adults. The clinical characteristics of Goods syndrome are increased susceptibility to bacterial infections with encapsulated organisms and opportunistic viral and fungal infections. The most consistent immunological abnormalities are hypo-gammaglobulinaemia and reduced or absent B cells. 