<prompt> Which of the following antiretroviral therapy is contraindicated in pregnancyNevirapineEfavirenzLamivudineStavudine  <response>: Efavirenz 1172- CMDT- 08 300 - 301- Dutta 6thEFAVIRENZ - Advantage - once daily in single doseSide effects - Neurologic, lack of concentration, delusion and mania Efavirenz should be avoided in women who wish to concieve or already pregnant due to teratogenicity Vertical transmission to the neonates is about 14-25 and majority 40- 80 occurs during the labours The median time from infection to AIDS is about 10 years Triple chemotherapy is preferred as a first line defence and to be started any time between 14 and 34 weeks and then continued throughout pregnancy, labour and postpartum period Minor risk associated with breast feeding Barrier methods of contraceptions Condome or female condome is effective in preventing transmission of the virus Most Ascian countries the infection rate is less than 0.5 