<prompt> Which of the following is a disadvantage of topically applied sodium fluoride solution?Need to prepare a fresh solution for each patientTaste is not well accepted by patientsPatient must make four visits to the dentist within a relatively short period of timeThe solution should be allowed to dry for 5 minutes  <response>: Advantages of neutral sodium fluoride solution-1. It is relatively stable when kept in a plastic container and there is no need to prepare a fresh solution for each patient. 2. The taste is well accepted by patients. 3. The solution is non-irritating to the gingiva. 4. It does not cause discoloration of tooth structure. 5. Once applied to the teeth, the solution is allowed to dry for 3 minutes. Thus the clinician in public health programs can pursue a multiple-chair procedure. 6. The series of treatments must be repeated only four times in the general age range of 3 to 13, rather than at annual or semiannual intervals, therefore in a public health program, other groups of children can be treated in theJintervening years. Disadvantage of neutral sodium fluoride solution-1. The major disadvantage of the use of sodium fluoride is that the patient must make four visits to the dentist within a relatively short period of time. 