<prompt> Kostmann;s syndrome-treatment isAnti-thymocyte globulin cyclosporinAnti-thymocyte globuline cyclosporine GM-CSFG-CSFGM-CSF  <response>: kostmann syndrome characterized by hereditary neutropenia and treatment of choice is administration of granulocyte colony stimulating factor. Severe Congenital Neutropenia Kostmann;s Syndrome Clinical manifestations: Chronic severe neutropenia present at bih Accumulation of granulocytic precursors in the bone marrow Recurrent infections Treatment with G-CSF -- Reduces infections and improves survival Marked propensity to develop acute myeloid leukemia or myelodysplasia Reference: GHAI Essential pediatrics, 8th edition 