<prompt> Poor prognostic factor in ALL are -Philadelphia chromosomeMale sexHigh WBC countHyperploidy  <response>: Person with t9,22 positive-ALL 30 of adult ALL cases and other Bcr-abl-rearranged leukemias are more likely to have a poor prognosis, but survival rates may rise with treatment consisting of chemotherapy and Bcr-abl tyrosine kinase inhibitors Ref Davidson 23rd edition pg 933 