<prompt> Inhibition of 5-lipooxygenase is useful in:Cardiac failureBronchial asthmaHepatic failureArthritis  <response>: Ans. B Bronchial asthmaRef: KDT 8the p248, 249Leukotrienes are potent bronchoconstricting agents. These agents play a major role in the pathogenesis of bronchial asthma. The drugs acting by inhibiting their synthesis i.e. lipoxygenase inhibitors or action Cys-LT receptor antagonists, are useful in the prophylaxis of bronchial asthma. 