<prompt> Darling disease is caused by -HistoplasmaCandidaCryptococcusRhizopus  <response>: Histoplasmosis or Darlings disease is caused by dimorphic fungus - Histoplasma capsulatum. It is called Darlings disease because it was found by Samuel Darling in histopathologic specimens about a century ago. Reservoir: Humid and acidic soil containing bird or bat droppings. Clinical Manifestations: Pulmonary histoplasmosis: It is the most common form. Acute form stas as mild flu like illness Chronic form - Cavitary histoplasmosis Disseminated histoplasmosis develops if CMI is very low as in HIV. 