<prompt> In VonGierkes disease, the levels of ketone bodies are increased due to all EXCEPT:The patients have hypoglycaemiaThe patients have low blood glucosemore mobilization of fatsOAA is required for gluconeogenesis  <response>: Type I Glycogen storage disease is known as Von Gierkes disease. Enzyme deficient is Glucose-6-Phosphatase. This enzyme is common for two pathways - Glycogenolysis Gluconeogenesis. Therefore in type I disease, both glycogenolysis gluconeogenesis cannot occur leading to very severe hypoglycemia ketosis occurs because of severe hypoglycemia. Ketone body synthesis in starvation vs Von Gierkes disease: In starvation in starvation - Gluconeogenesis is - removal of OAA for gluconeogenesis - TCA cycle hampered - acetyl-CoA builds up - ketone body synthesis So ketosis occur due to lack of OAA. In von Gierkes disease Gluconeogenesis and glycogenolysis not occurring due to lack of common enzyme - Hypoglycemia - ketone body synthesis So ketosis occurs due to hypoglycemia and not due to lack of OAA. hence the reason for increased ketone body synthesis in Von Gierkes disease is not the use of OAA for Gluconeogenesis. Hence Option D is a wrong statement and is the Answer. 