<prompt> Deficiency of Arylsulphatase is seen inGauchers diseaseMetachromatic Leuko Dystrophy MLDTay-Sachss diseasNiemann-Pick disease  <response>: B Metachromatic leukodystrophy MLD Metachromatic leukodystrophy MLD is a lysosomal storage diseases, which are progressive, inherited, and neurodegenerative disorders MLD included. 4 types of MLD occur with varying ages of onset and courses i.e., 1. Late infantile, 2. Early juvenile, 3. Late juvenile, 4. Adu t. All forms of MLD involve a progressive deterioration of motor neurocognitive function. The typing is somewhat arbitrary, as the types overlap, and some cases do not fall neatly within a single type. MLD actuall describes a continuum of clinical severity. The presence of white matter abnormalities on brain images is characteristic. Pathophysiology: In patients, the inability to degrade sulfated glycolipids, especially the galactosyl-3-sulfate ceramides, characterizes MLD. A deficiency in the lysosomal enzyme sulfatide sulfatase arylsulfatase A is present in MLD. 