<prompt> Sphingomyelinase deficiency is seen inNiemann - Pick diseaseFarbers diseaseTay Sachs diseaseKrabbes disease  <response>: DiseaseEnzyme DeficiencyClinical SymptomsNiemann-PickdiseaseSphingomyelinaseEnlarged liver and spleen, mental retardation;fatal in early lifeRef: Harper;s Biochemistry; 30th edition; Chapter 24; 24 Metabolism of Acylglycerols Sphingolipids 