<prompt> With reference to neoplasia, the term tumor progression meansSpread of cancer to distant sitesRate of growth of tumorsAbi1ity of cancer cells to resemble their normal counterpaSequential appearnace of features of increasing malignancy  <response>: Multi step.theory of carcinogenesis Phy.attributes are .self sufficient in growth signal .local invasion ,metastasis .karyotic pattern .hormonal response .response to Anti malignant drugs Evading apoptosis All these acquired in a step wise fashion This phenomenon is tumour progression 