<prompt> A 23-yeard-old college student has asympt-omatic and hyperpigmented macules on both palms for three weeks. The most appropriate diagnostic test is:Veneral Diseases research Laboratory VDRL testSkin biopsySerum coigol levelsAssay for arsenic in skin, hair nails  <response>: A i.e. Veneral Disease Laboratory VDRL Estimation of coisol levels are not indicated as only skin lesions without other symptoms is disouring adrenal pathology. Assay of arsenic is not required as arsenic poisoining will always present with systemic symptoms. Skin biopsy is not indicated as only presentation is hyperpigrnented macules. So the answer is straight forward - As secondary syphilis usually presents with BL symmetrical So the answer is straight forward - As secondary syphilis usually presents with BL symmetrical 