<prompt> ABC transpoerP glycoproteinMembrane sparingChannelAdenylyl cyclase  <response>: P-glycoprotein 1 permeability glycoprotein, abbreted as P- gp or Pgp also known as multidrug resistance protein 1 MDR1 or ATP-binding cassette sub-family B member 1 ABCB1 or cluster of differentiation 243 CD243 is an impoant protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi, and bacteria and likely evolved as a defense mechanism against harmful substances. Ref: 