<prompt> An 18-year-old girl presents with amenorrhoea, milk discharge, weight loss. Diagnosis isPituitary CancerAnorexia nervosaHypothyroidismHypothalamic cause  <response>: Its tempting here to go for Hypothyroidism but that is usually associated with weight gain. However, pituitary tumors and craniopharyngiomas can cause increase in PRL and consequent galactorrhea , weight loss attributed then to the malignant process. Ref - Harrison 20e pg2673 