<prompt> A 56 year old chronic smoker, mass in bronchus resected. What is the possible marker-CytokeratinVimentinEpithelial membrane CadherinLeukocyte  <response>: Ref:Harrison;s principle of internal medicine ,18 th edition, page no. 739 The diagnosis of lung cancer most often rests on the morphologic or cytologic features correlated with clinical and radiologic findings. Immunohistochemistry may be used to verify neuroendocrine differentiation within a tumour, with markers such as neuron specific enolase NSE,CD56 or neural cell adhesion molecule NCAM, synaptophysin, chromograin, and Leu7.Cytokeratin 7 and 20 used in combination can help narrow the differential diagnosis; Non-Small Cell Lung Cancer , Small Cell Lung 