<prompt> Behcets syndromes is characterized by all, Except:MyocarditisErythema NodosumOral and Genital ulcersThrombophlebitis  <response>: Answer is A Myocarditis: Myocarditis has not been mentioned as an association with Behcets syndrome. Behcets syndrome may present with recurrent oral and genital ulceration, Thrombophlebitis and Erythema Nodosum Skin lesions Behcets syndrome Behcets syndrome is a chronic multisystem relapsing vascular inflammatory disease vasculitis of unknown origin Behcets disease is primarily a small vessel vasculitis but is can also involve large vessels both aeries and veins. Behcets disease is associated with HLA-B5 rather than HLA B27 Disease pf young people 20 parQ Males affected equally as femalesQ HLA B5 positiveQ Diagnostic criteria Essential criteria plus two of the non essential criteria are required for diagnosis Essential criteria Recurrent oral Ulceration Oral ulceration is the hallmark of diseaseQ These are sin qua non for the diagnosis Types of Ulcers include - Minor Aphthous - Major Aphthous - Herpetiform ulcers - Features of oral ulcers - PainfulQ - Shallow with a central yellowish necrotic base - Appear singly or in crops - Subside without leaving scars persist for 1-2 weeks Non-Essential criteria Recurrent Genital Ulcers Less common but more specific Do not affect glans or urethra Produce scars scrotal scars Eye lesions : Uveitis Anterior Uveitis Recurrent Hypopyon Posterior uveitis Retinal vasculitis Skin lesions Erythema nodosum Pseudofolliculitis Pseudopustular lesions Acneiform nodules Positive Pathergy Test Pathergy refers to hyperreactivity of skin to any intracutaneous injection or needle stick Pathergy is characteristic feature of Behcets although the mechanism is unknown Pathergy test is said to be positive if a papule or pustule 2mm develops 24-48 hrs after needle prick to a depth of 5 mm. 