<prompt> IL-1 is secreted from which cellsMast cellsEosinophilsMacrophagesNeutrophils  <response>: Tumor necrosis factor TNFInterleukin-1 IL-1Granulocyte-monocyte colony-stimulating factor GM-CSFGranulocyte colony-stimulating factor G-CSFMonocyte colony-stimulating factor M-CSFThese factors are formed by activated macrophage cells in the inflamed tissues and in smaller quantities by other inflamed tissue cells.Ref: Guyton and Hall textbook of medical physiology 13th edition. Page:462 