<prompt> Increased alkaline phosphate in seen in -a Multiple myelomab Primary hyperparathyroidismc Chronic renal failured Osteoporosisacbcad  <response>: Whenever the activity of osteoblasts increase, serum alkaline phosphatase is raised. Therefore, serum alkaline phosphatase acts as an index of osteoblastic activity.The conditions in which osteoblastic activity is increased and hence the alkaline phosphatase in increased are : -Ricketsosteomalacia Primary hyperparathyroidism Renal osteodystrophy secondary hyperparathyroidismChronic renal failure and secondary hyperparathyroidismPagets disease osteitis deformansOsteoblastic secondaries 