<prompt> Which of the following is NOT associated with elevation of prostatic specific antigen?Acute prostatitisBPHProstatic intraepithelial neoplasmProstatic needle biopsy  <response>: Prostatic Intraepithelial Neoplasia PIN is a precancerous condition; not detected by rectal examination, TRUS , or MRI; does not cause rise in PSA level . It is usually identified after TURP for BPH with final histology or by prostatic biopsy.Reference: page1048 SRB;s manual of surgery 5th edition 