<prompt> Which of the following liver enzymes is predominantly mitochondrial?SGOT ASTSGPT ALTGGT5 Nucleotidase  <response>: In old literature, it was called as serum glutamate oxaloacetate transaminase SGOT. AST needs pyridoxal phosphate vitamin B6 as co-enzyme. Normal serum level of AST ranges from 8 to 20 UL. It is a marker of liver injury and shows moderate to the drastic increase in parenchymal liver diseases like hepatitis and malignancies of the liver.Ref: DM Vasudevan, Page no: 269 