<prompt> Which is autosomal dominantGyrate AtrophyBest DiseaseLawrance Moon Biedl SyndromeBassen Komzweigs Disease  <response>: B i.e. Best Disease Best disease vitelliform dystrophy occurs dt mutation of bestrophin VMD2 gene on 11q13 chromosome and has autosomal dominant inheritence ADQ. It has lipofuscin accumulation through out the RPE. It is typified by a large yellow yolk like vitelliform lesion giving characteristic egg yolk appearance, that is bilateral symmetrical in the central macula and appears during childhood 3-15 years. The visual acuity is usually good when the yolk remains intact and drops once scarring begins. 