<prompt> Menadione Vitamin K3Can cause hemolysis in a patient with G-6-PD deficiencyIs the preparation of choice to antagonize the effect of warfarin overdoseIs useful to prevent hemorrhagic disease of the newbornIs given in large doses in patients with severe liver disease  <response>: Menadione is fat-soluble synthetic vitamin K3. It can cause hemolysis in G-6-PD deficient individuals. In severe hepatic disease, large doses of menadione can further depress liver function. Menadione is not used to prevent haemorrhagic disease of the newborn as it can cause kernicterus, instead phytonadione is used. Phytonadione is also the drug of choice to overcome the toxic effects of warfarin as it acts rapidly. 