<prompt> Target fibres are characteristically seen in a muscle biopsy of -DermatomyositisMotor neuron diseaseMyasthenia gravisDrug induced myopathy  <response>: Target fibersDuring denervation atrophy there is a cytoskeletal reorganization of some muscle cells, which results in a rounded zone of disorganized filaments in the centre of the fiber target fiber.Amongst the given options only motor neuron disease can result in denervation of the muscle. 