<prompt> As per WHO 2010 guidelines, when should an HIV infected adult be staed on anti retroviral therapy?CD4 count less than 600 irrespective of stagingCD4 count less than 350 irrespective of stagingCD4 count less than 500 irrespective of stagingCD4 count less than 450 irrespective of staging  <response>: Target population 2010 A guideline 2006 A guideline HIV asymptomatic ARV-naive individuals CD4 350 cellsmm3 CD4 200 cellsmm3 HIV symptomatic ARV-naive individuals WHO clinical stage 2 if CD4 350 cellsmm3 OR WHO clinical stage 3 or 4 irrespective of CD4 cell count WHO stage 2 or 3 and CD4 200 cellsmm3 WHO stage 3 if CD4 not available WHO stage 4 irrespective of CD4 cell count Consider treatment for WHO clinical stage 3 and CD4 cell count between 200 and 350 cellsmm3 HIV pregnant women CD4 350 cellsmm3 irrespective of clinical symptoms OR WHO clinical stage 3 or 4 irrespective of CD4 cell count WHO stage 1 or 2 and CD4 200 cellsmm3 WHO stage 3 and CD4 350 cells mm3 WHO stage 4 irrespective of CD4 count Ref: Epidemiology of communicable diseases Parks textbook of Preventive and Social Medicine, 21stedition, page-327. 