<prompt> A 50 years old male with 2 diabetes mellitus is found to have 24 hour urinary albumin of 250 mg. Which of the following drugs may be used to retard progression of renal disease -HydrochlohiazideEnalaprilAmilorideAspirin  <response>: Ans is option 2 - Enalapril ACE inhibitors and ARB;s are specifically indicated to reduce progression of renal disease. Ref Harrison 19 2428 