<prompt> More than 90 of this drug is excreted in the urine intact form. Because its urinary solubilities low, patient should be well hydrated to prevent nephrotoxicity.the drug isIndinavirZidovudineAcyclovirAmantadine  <response>: Ref-KDT 6 769 Both indinavir and acyclovir can cause nephrotoxicity and renal stone formation.but indinavir is metabolized mainly in the liver and acyclovir is excreted unchanged in the urine 