<prompt> All of the following statements regarding progressive multifocal leucoencephalopathy are true exceptPatient commonly presents with visual disturbances and speech defectsIt is most commonly seen in immunocompromised personsDiagnosis is frequently suggested by MRJIt follows an indolent course and patient usually dies within 6 months  <response>: Harrisons principles of internal medicine 17th edition. Almost all patients with PML have an underlying immunosuppressive disorder.demyelination is distributed throughout brain sparing spinalcord and optic nerve. The diagnosis of PML is frequently suggested by MRI.No effective therapy is available and patient usually dies within 6 months 