<prompt> A 32-year-old female, asymptomatic, not requiring blood transfusion, presents with Hb 13.0 gmdl. Her HbF levels levels are 95, Hb A2 1.5. Which of the following is the most likely diagnosis?Hereditary persistence of fetal hemoglobinBeta homozygous thalassemiaThalassemia intermediaBeta heterozygous thalassemia  <response>: - In given pt, even though HbF levels are elevated, these pts have normal Hb levels asymptomatic without any requirement of any transfusions. Hence, thalassemia is ruled out - These features points towards the diagnosis of Hereditary persistence of fetal hemoglobin HPFH - It is benign condition in which fetal hemoglobin HbF production is increased continued into adulthood Patient remains asymptomatic even without blood transfusion No anemia; no splenomegaly 