<prompt> The pathogenicity of E. histolytica is indicated by:Zymodeme patternSizeNuclear patternELISA test  <response>: Ans. is a i.e., Zymodeme patternZymodeme isoenzyme analysis: E. histolytica possesses several isoenzymes like malic enzyme, hexokinase, isomerase and phosphoglucomutase and these isoenzymes contribute in pathogenesis. When these isoenzymes are subjected to electrophoresis based on electrophoretic pattern Zymodeme pattern and mobility of these isoenzymes, Entamoeba can be diagnosed and speciated. 