<prompt> Which of the following anticancer drugs are competitive inhibitors of tyrosine kinase -Imatinib and suntinibLetrozoleBicalutamideFulvestrant  <response>: Ans. is a i.e., Imatinib and suntinib Molecular targeted agentso Tyrosine kinase inhibitorsCompetitive inhibitors - Imatinib, Nilotinib, Sunitinib, Dasatinib, Erlotinib, Gefitinib, Lapitinib, Sorafinib Remember all ends with nib .Monoclonal antibodies - Cetuximab, panitumomab.o HER2neu ERB B2 inhibitors - Monoclonal antibody - Transtuzumab.o Targeted antibody - Gemtuzomab anti CD-33, Rituximab anti - CD20, Alemtuzumab anti CD-52,o Vascular endothelial growth factor VEGF inhibitor - Monoclonal antibody - Bevacizumab.o Proteosome inhibitors - Bortezomib.o Histone deacylase inhibitor - Vorinostato DMA - methyl transferase inhibitor - 5-azacytidine, 2-deoxy-5 azacytidine.o All - trans - retinoic acid.o Biological response modifier - Recombinant IL-2 aldesleukin, denileukin. 