<prompt> Hurthle cells are characteristically seen in which of the following thyroid disease?Hashimotos thyroiditisGraves diseasede Quervains thyroiditisSubacute lymphocytic  <response>: A Hashimotos thyroiditis Robbins8 - 1112, 1113; Robbins7 - 1169 Hurthle cell is a cell in the thyroid that is often associated with Hashimotos thyroiditis as well as follicular thyroid cancer Histology: Hurthle cells are characterized as enlarged epithelial cells with abundant eosinophilic granular cytoplasm as a result of altered mitochondria. They generally stain pink and are prominently found in histological sections of thyroid glands affected with Hashimotos. Clinical significance: A Hurthle cell adenoma is a type of thyroid benign tumor that, in rare cases, has the potential to become malignant and metastasize Hurthle cell carcinoma. Hurthle cells are also found in Hashimotos thyroiditis and toxic and nontoxic nodular goiter. Hurthle cells are hypothesized to be of follicular epithelial origin. 