<prompt> Hemophilia is associated with -X ChromosomeY ChromosomeChromosome 3Chromosome 16  <response>: Ans. is a i.e., X chromosome o Hemophilia A is caused due to defect or decrease in factor VIII.o The factor VIII gene is one of the largest genes known comprising about .lof the X chromosome.o Factor VIII contains several areas of internal homology .Hemophilia A geneso Hemophilic gens does not demonstrate a uniform abnormality, instead numerous different mutations in the Factor VIII gene have been described.o Seven different mutations have been demonstrated in the hemophilia gene.o Most common mutation associated with hemophilia A is major inversion of a section of the tip of the long arm of X chromosome. 