<prompt> Commonest surgical procedure for soft tissue sarcomaMarginal excisionEnucleationWide local excisionCompamental excision  <response>: Soft Tissue SarcomaRare unusual neoplasm of soft tissuesMC site: Extremity lower upper Trunk Retroperitoneum Head NeckMC type: Malignant fibrous histiocytomaLiposarcoma Leiomyosarcoma Synol sarcoma Malignant peripheral nerve sheath tumorMC pediatric soft tissue sarcoma: RhabdomyosarcomaHistopathological Type of STSExtremityRetroperitoneumVisceraMalignant fibrous histiocytoma LiposarcomaLiposarcomaGISTPathologyDiagnosis of Soft tissue sarcomaSTS tends to grow along fascial planes, with the surrounding soft tissue compressed to form a pseudocapsule.Clinical behavior of STS is determined by: Anatomic location depth, grade sizeMC route of spread in soft tissue sarcoma: HematogenousMC site of metastasis: LungCore-cut or true-cut biopsy CT or USG guided is diagnosticIncisional biopsy is done if core-cut biopsy is non-diagnosticFNAC: To confirm or rule out presence of metastatic focus or local recurrenceMRI: IOC for assessing extremity STSCECT: IOC for assessing retroperitoneal sarcomaClinical featuresTreatmentMC symptom of STS: Painless massSize at presentation is dependent on the location of tumor.Smaller tumors - distal extremitiesLarger tumors - proximal extremity retroperitoneumAdequate excision adjuvant radiotherapy with or without adjuvant chemotherapy.PrognosisBest prognostic factor of soft tissue sarcoma: GradingBest prognosis is seen in: ExtremitySTSMC cause of death in STS: Metastasis; 5-year survival rate for STS all stages: 50-60Refer: Devita, Hellman, Rosenbergs Cancer Principles and Practice of Oncology, 9th edition, pg no: 1533-1552 