<prompt> Not controlled directly by ACTH-GlucocorticoidsAldosteroneDHEAEpinephrine  <response>: Ans. is D i.e., Epinephrine o The question is very simple. o Adrenocorticotropin hormone ACTH, as the name indicates, stimulate adrenal cortex. o Epinephrine is secreted by adrenal medulla other three hormones given in question are secreted by adrenl cortex, o ACTH has its main and most important effect on secretion of glucocorticoids cortisol. o The effect on secretion of mineralocorticoids aldosterone and androgens DHEA : dehydroepiandrosterone in minimal but some effect is there, which is not major regulatory mechanism. o It should be remembered that, though ACTH does not have a direct effect on epinephrine secretion, it increases epinephrine secretion indirectly as epinephrine secretion is dependent on cortisol. 