<prompt> The gene expression of which of the following enzymes is not increased by insulin?Pyruvate CarboxylaseAcetyl CoA CarboxylasePhosphofructokinase-1Pyruvate Dehydrogenase  <response>: Enzymes where gene expression is increased by Insulin: Enzymes where gene expression is decreased by Insulin: usually enzymes of glycolysis, link reaction, HMP, fatty acid synthesis Hexokinase II Hexokinase IV Phosphofructokinase-I PFK-I, PFK-II Pyruvate Kinase Glucose 6 Phosphate Dehydrogenase G6PD Pyruvate Dehydrogenase Acetyl CoA Carboxylase Malic enzyme ATP Citrate Lyase FA Synthase Complex usually enzymes of gluconeogenesis Phosphoenol Pyruvate Carboxylase PEPCK Glucose 6 Phosphatase Gluconeogenesis Extra Edge : Insulin Glucagon 1.activates all anabolic pathways enzymes i.e. HMP, Glycogenesis, FA synthesis, Cholesterol synthesis, TG synthesis, Lipoprotein Lipase enzyme. 2.activates two catabolic pathway enzymes i.e. Glycolysis Link reaction. 1.activates all catabolic pathways enzymes i.e. Glycogenolysis, beta oxidation of fatty acids, Gluconeogenesis, Ketone body synthesis, Ketone body utilization. Except two catabolic pathway enzymes i.e. Glycolysis Link reaction, as these are activated by Insulin. 