<prompt> Fulminant hepatitis E is seen in?Pregnant womenInfantsMalnourished malesAdolescents  <response>: ANSWER: A Pregnant womenREF: Park 18th ed p. 174, Robbins 7th ed 891 table 18-6Important points about hepatitis E:Transmitted by feco-oral routeFulminant hepatitis E seen in pregnant women 20-40 especially in last trimesterMost common cause opf sporadic cases of hepatitis in adults - Hepatitis EEpidemics are almost exclusively caused by enetrically transmitted Hepatitis E Hepatitis AHepatitis BHepatitis CHepatitis DHepatitis EHepatitis GAgentIcosahedral capsid, ssRNAEevelopeddsDNAEnvelopedssRNAEnvelopedssRNANon enveloped ssRNAssRNATrans-missionFecal oralParenteral, dose contactParenteral, close contactParenteral, close contactWaterborneParenteralIncubationperiod2-6 wks4-26 wks2-26 wks4-7 wks2-8 wksUnknownCarrier stateNone0.1-1 of blood donors in U.S west0.2-1 of blood donors in U.S west1-10 in drug addicts hemophiliacUnknown1-2 of blood donors in U.SChronic hepatitisNone5-10 of acute infections50 5 coinfection, 80 upon super infectionNoneNoneHepato-cellularcarcinomaNoYesYesNo increase above HBVUnknown but unlikelyNone 