<prompt> Mechanism of action of chloramphenicol is-Preventing binding of t RNA to ribosomeCell wall lysiscessation of peptide chain elongationInhibiting cell wall synthesis  <response>: Tetracyclines are the drugs that bind to 30S ribosomes and inhibit binding of aminoacyl tRNA to ribosomes. Chloramphenicol binds to 50S ribosome and interferes with peptide bond formation and transfer of peptide chain from p site to a site thereby inhibiting polypeptide elongation Ref : essentials of medical pharmacology by KD Tripathy Chloramphenicol binds to 50S subunit--interferes with peptide bond formation and transfer of peptide chain from P site. 