<prompt> Most common cause of End stage renal disease is:DiabetesHypertensionChronic GNPolycystic Kidney disease  <response>: Ref: Harrisons Principles of Internal Medicine. 18ed.Explanation:The dispiriting term end-stage renal disease should not be used and is replaced by the term stage 5 CKDThe most frequent cause of CKD is diabetic nephropathy. most often secondary to type 2 diabetes melli- tus Ref: HarrisonLeading Categories of Etiologies of CKDDiabetic glomerular disease MC CauseGlomerulonephritisHypertensive nephropathyPrimary glomerulopathy with hypertensionVascular and ischemic renal diseaseAutosomal dominant polycystic kidney diseaseOther cystic and tubulointerstitial nephropathy 