<prompt> Wine Glass appearance on T2W-MRI BRAIN is seen with?Metachromatic LeukodystrophyCanavans DiseaseCreutzfeld Jacob DiseaseAmyotrophic Lateral Sclerosis  <response>: Wine Glass Sign on MRI Brain T2-weighted imaging, black arrow shows hyperintensity in the posterior bilateral internal capsule and bl coicospinal tracts with classical wine glass appearance in ALSLou Gehrigs disease 