<prompt> Organophosphates bind toAnionic site of AChEsEsteratic site of AChEsAchNone  <response>: Ref: KDT 6e p99-100 The active region of Acetylcholinesterase AChE has two sites i.e. an anionic site and an esteratic site. Anticholinesterase poisoning like Organophosphate compounds binds to esteratic site of AChE. 