<prompt> Mediators of inflammation are all except -TNFIFNMyeloperoxidaseProstaglandinsInterleukins  <response>: Mediators of inflammation:-The vascular and cellular reactions of both acute and chronic inflammation are mediated by chemical factors known as a mediator of inflammation.Mediators originate either: -1. From plasmaComplement proteins, Bradykinin2. From cellsCells derived mediators may be performed and are stored in secretory granules or they may be synthesized de novo in response to a stimulus.Preformed mediators Histamine, Serotonin, Lysosomal enzymes.Newly synthesized Prostaglandins, Leukotrienes, platelet activating factors, nitric oxide, reactive oxygen species, cytokines TNF, IL-1.Myeloperoxidase is not an inflammatory mediator. It is an enzyme of neutrophil which catalyzes the conversion of Cl, Br, and T, and SCN to the corresponding acids HOCl, HOBr etc.. These acids are potent oxidants and help in destroying the invading organisms.Mediators of Acute inflammation 