<prompt> Hyperophic gastropathy is seen in -Seen in menetriers disease and ZESIt is associated with malignancyIt shows cerebriform rugacity on stomachAll  <response>: Ans. is a i.e., Seen in Menetriers disease and ZES; b i.e., It is associated with malignancy; c It show cerebriform rugacity on stomachHyperophic Gastropathyo Hyperophic gestropatny is a group of uncommon conditions , all characterized by giant cerebrifrom enlargement of the rugal folds of the gastric mucosa.o The rugal enlargement is caused by hyperplasis of the mucosal epithelial cells, without inflammation . o Three variant are recognizedMenetrier disease -- Resulting from profound hyperplasia of the surface mucous cells with accompanying glandular actrophy.Hyperophic - hypersecretory -- Associated with hyperplasia of the parietal and chief cells gastropathy within gastric glands.Zollinger -Ellison syndrome - Gastic gland hyperplsia due to excessive gastrin secretion by gastrinoma.o Menetier disease may involve predominantly the body - fundus or antrum or the entire stomach.o Mucosal hyperplasia may becomes metaplastic, providing a soil for the development of gastric carcinoma. 