<prompt> The treatment of gestational diabetes comprise of:GlibenclamideChlorpropamideGlipizideInsulin  <response>: Gestational diabetes is defined as glucose intolerance first detected during pregnancy which returns to normal following termination of pregnancy. It is associated with 2 to 3-fold increase in perinatal mortality. It is frequently associated with macrosomia, stillbirth and polyhydramnios. To restrict the plasma glucose levels around 100 mg insulin may be required. Sulfonylureas cross the placental barrier and are likely to exert their action on fetal pancreas.It is better to use human insulin or monocomponent purified insulins, as they are less antigenic. 