<prompt> A reversible change occurring in which a mature cell type is replaced by another mature cell, is called:DysplasiaMetaplasiaHyerplasiaHypertrophy  <response>: Ref: Robbins Pathology, 9th ed. pg. 37 Metaplasia is an adaptive response of a cell in response to stress. It is a reversible change in which a differentiated mature cell type is replaced by another differentiated cell type. It can be of two types: Epithelial metaplasia Squamous metaplasia: MC seen in respiratory tract in response to smoking where columnar epithelium is replaced by squamous epithelium. Glandular metaplasia: Metaplasia of squamous epithelium into columnar glandular epithelium. Example Barrets esophagus metaplasia of stratified squamous epithelium of esophagus is replaced by intestinal-like columnar cells. Connective tissue metaplasia: One type of connective tissue is replaced by another. Example: Myositis ossificans. Hypertrophy: Increased cell size in response to increase in workload. It occurs in tissues incapable of cell division. Hyperplasia: increase in cell number in response to growth factors or hormones. Atrophy: Decrease in cell and organ size as a result of disuse or decreased nutrient supply. 