<prompt> Mc Ardles disease is due to deficiency ofLiver phosphorylaseMuscle phosphorylaseGlycogen phosphorylaseGalactase  <response>: Glycogen storage diseases TYPE NAME DEFICIENT ENZYME CLINICAL FEATURES Type I von Gierkes disease Glucose-6-phosphatase Fasting hypoglycemia; hepatomegaly,thrombocyte dysfunction. Type II Pompes disease Lysosomal maltase Accumulation of glycogen in lysosomes of liver, hea and muscle; death before 2 years Type III Limit dextrinosis Coris disease Debranching enzyme Highly branched dextrin accumulates; Fasting hypoglycemia; hepatomegaly Type IV Amylopectinosis Andersons disease Branching enzyme Glycogen with few branches; hepatosplenomegaly; mild- -hypoglycemia; death by age of 5 Type V McArdles disease Muscle phosphorylase Excercise intolerance; accumulation of glycogen in muscles Type VI Hers disease Liver phosphorylase Mild hypoglycemia; hepatomegaly; better prognosis than other types REF: DM VASUDEVAN TEXTBOOK OF BIOCHEMISTRY,EIGHTH EDITION,PG.NO.,144. 