<prompt> Which of the following inhalational agent is contraindicated in renal disease?MethoxyfluraneSevofluraneDesfluraneIsoflurane  <response>: Methoxyflurane produces inorganic fluoride, which was responsible for the sporadic incidence of nephrotoxicity i.e., high-output renal failure after prolonged anesthesia Basics of anesthesia 7e pg:95 