<prompt> All of the following predispose to chloroquine toxicity except?Duration of use 2 yearsCumulative does 460 ginDaily dose 250 mgd or 3 mgkgRenal failure  <response>: Ans is a i.e. Duration of use 2 years Risk Factors of Chloroquine toxicity Duration of Disease 5 years Daily dose Hydroxychloroquine: 400 mgday 6.5 mgkg Chloroquine: 250 mgday 3.0 mgkg Cumulative dose Hydroxychloroquine: 1000 gm Chloroquine: 460 gm Age Elderly 60 years Physique Sho stature, obese Systemic disease Liver or kidney dysfunction Ocular disease Retinal disease or Maculopathy. 