<prompt> ADAMTS 13 is associated with which of the following disorders?TTPChurg Strauss syndromeWegeners granulomatosisMembranous nephropathy  <response>: ADAMTS 13:- -Metalloprotease enzyme which inhibits VWF clumps. -cleaves VWF multimers into smaller monomers for eventual degradation Thrombotic Thrombocytopenic purpura TTP- Causes- Deficiency of ADAMTS 13 Ab formation against ADAMTS 13 - ADAMTS 13 activity - VWF clumping - Platelet-Thrombi present CF - Thrombocytopenia Microangiopathic Hemolytic anaemia Fever Renal failure CNS features Rx- Plasmapheresis 