<prompt> A 10-day-old male pseudohermaphrodite child with 46 XY karyotype presents with BP of 11080 mm Hg. Most likely enzyme deficiency is:21 hydroxylase17 hydroxylase11 hydroxylase3-beta hydroxylase  <response>: b. 17 hydroxylaseRef: Nelsons 20e p 2714-2423, Ghai 8e p 526-527In 17-hydroxylase deficiency: All pregnonolone is converted to mineralocorticoid. So, there will be:Excess of mineralocorticoids - Salt retention and hypertension.No androgens - Feminization of external male genitalia, while genitalia development will be normal in femalesComing back to this question, this neonate has: Hypertension normal BP in a neonate 7550 and male pseudohermaphroditism, both of which are features of 17-alpha hydroxylase deficiency. 