<prompt> Which of the following in anesthesia will produce decreased EEG activitiesHypothermiaEarly HypoxiaKetamineN20  <response>: A i.e. Hypothermia Hypothermia causes progressive slowing of brain activity at core temperatures below 35degC. Severe hypothermia progressive decrease in EEGQ. Situation Effect On EEG - Hypothermia 35degC Progressive slowing of EEGQ - Profound hypothermia 7- 20degC Complete electrical silent CO2 level - Hypocarbia - Slowing of EEG - Hypercarbia 5-20 - Decreased cerebral excitability increased electroshock seizure threshold - Hypercarbia 30 above normal - Increased cerebral excitability epileptiform discharge - Hyper carbia 50 above normal - EEG depression. 02 levels - Hyperoxia - Cerebral excitation 1t low amplitude fast frequency EEG - Early thypoxia - Cerebral excitability dt peripheral cemoreceptor stimulation - Persistent Hypoxia Vt. acute increase in amplitude of EEGQ - Late Hypoxia approching anoxia - Diffuse slowing of EEGQ Vt marked reduction in amplitude with appearance of slow wavesQ - EEG silence Sensory stimulation in awake Desynchronization of EEG patterns, increased amplitude, and increased frequency. Narcotic Analgesics - Low dose - Increase amplitude of both a p bands. - High dose - Theta delta frequencies develop heralding the onset of sedation Enflurane Dose dependent depression of EEG activity, but at moderate high concentration 3, it produces epileptiform paroxymal spike activity and burst suppressionQ. It should be avoided in epileptic patientsQ. - No seizure activity on EEG excitatory effects as seen in Isoflurane, Desflurane and enflurane - Dose dependent depression of EEG activity Sevoflurane - Does not cause seizure activity at any level of anesthesia with or without hypocapnia. Propofol - EEG frequency decreases amplitude increase Ketamine - Unlike those seen with other IV. anesthetics, and consists of loss of alpha rhythm and predominant theta activityQ. 