<prompt> Which of the following is related to NARP?Glycogen storage diseasesLipid storage diseaseProteinMitochondria  <response>: Neurogenic weakness, ataxia, and retinitis pigmentosa NARP is characterized by moderate diffuse cerebral and cerebellar atrophy and symmetric lesions of the basal ganglia. The substitution of one nucleotide in the mitochondrial DNA at position 8993 gives rise to a maternally inherited syndrome of sensory NARP. The mutation creates a defective ATPase-6 of complex V of the mitochondrial respiratory chain. When 95 of mtDNA molecules are mutant, a more severe clinical neuroradiologic and neuropathologic picture Leigh syndrome emerges. Ref: Skorecki K., Mandel H. 2012. Chapter e18. Mitochondrial DNA and Heritable Traits and Diseases. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J. Loscalzo Eds, Harrisons Principles of Internal Medicine, 18e. 