<prompt> A 6-month-old baby with severe pallor and hepatosplenomegaly. Similar history is present in a sibling. Investigation of choice:Bone marrow biopsyHb electrophoresisHb estimationPlatelet count  <response>: b. Hb electrophoresisRef: Nelsons 20e p 2323-2325, Ghai 8e p 334-335Presence of pallor and hepatosplenomegaly at 6 months of age with a positive family history indicates towards thalassemia major, which can be diagnosed by Hb electrophoresis. 