<prompt> A major causal factor in some cases of hypogonadism isReduced secretion of gonadotropin-releasing hormone GnRHHypersecretion of pituitary LH and FSH as the result of increased GnRHExcess secretion of testicular activin by Seoli cellsFailure of the hypothalamus to respond to testosterone  <response>: Reduced secretion of GnRH will result in extremely low levels of circulating LH and FSH, causing testicular atrophy, as in Kallmanns syndrome. 