<prompt> Which is the most characteristic finding in Osteomalacia?Abnormal osteoblastic activityCrystalline structure of boneIncreased deposition of osteoid with decreased mineralizationIncreased mineralization with decreased osteoid formation  <response>: Osteomalacia soft bone is a structural abnormality of bone caused by defective mineralization of osteoid, which is produced in normal or increased amounts. Because it is not calcified normally, affected bones are soft. The newly formed osteoid matrix laid down by osteoblasts is inadequately mineralized, thus producing the excess of persistent osteoid characteristic of osteomalacia.Microscopic examination of undecalcified bone shows the presence of uncalcified osteoid, usually in the form of wide seams on the outer aspect of bony trabeculae. This is diagnostic of osteomalacia. Ref: Chandrasoma P., Taylor C.R. 1998. Chapter 67. Diseases of Bones. In P. Chandrasoma, C.R. Taylor Eds, Concise Pathology, 3e. 