<prompt> The drug effective for treatment as well as prophylaxis of angina pectoris is:Isosorbide dinitratePentaerythritol tetranitrateDiltiazemDipyridamole  <response>: Isosorbide dinitrate Can be used sublingually at the time of attack peak in 5-8 min Orally for chronic prophylaxis. t 12 is 40 min, but sustained release formulation may afford protection for 6-10 hours. Nitrates are effective in classical as well as variant angina. Nitrates increase exercise tolerance and postpone ECG changes of ischemia. 