<prompt> Ram Prasad is admitted to Guru Teg Bahadur Hospital with respiratory infection for which antibiotic tobramycin is ordered. The clearance and vd of tobramycin in him are 160mlmin and 40L ,respectively.if you wish to give Ram Prasad and intravenous loading dose to achieve the therapeutic plasma concentration of 4mgL rapidly, how much should be given0.1mg10mg115.2mg160mg  <response>: Ref-Katzung 10e p45 Loading dise Vd xtarget Plasma concentration 40Lx4mgL 160mg clearance plays no role in the determination of loading dose. it is given to confuse you 