<prompt> Birt-Hogg-Dube syndrome associated with:Renal cell carcinomaLung CaStomach CaOvarian Ca  <response>: Ans: a Renal cell carcinomaRef: Brenner and Rectors The Kidney, 10th edition, Page 1372Birt-Hogg-Dube syndromeCharacterized by prominent cutaneous manifestations, the development of spontaneous pneumothorax in association with lung cystsPredisposition to kidney neoplasms chromophobe renal cancers, oncocytomas, or mixed oncocyticAffected gene is folliculinCharacteristic skin lesions, fibrofolliculomas hamartomas of the hair follicle, develop on the skin of the head and neck of patients with the syndrome after age 30Genetic syndromes associated with renal cell carcinomaVHL syndrome-clear cell histologyMultiple cutaneous and uterine leiomyomas MCULHereditary leiomyomatosis and renal cell cancer HLRCC syndromeBirt-Hogg-Dube syndromeTuberous sclerosis 