<prompt> Romanas sign is seen in?ToxoplasmaTrypanosoma cruziLoa loaWuchereria  <response>: Ans. b Trypanosoma cruzi Romana sign, also known as chagoma, refers to periorbital swelling, palpebral oedema and conjunctivitis seen 1-2 weeks following infection with Trypanosoma cruzi causative agent in Chagas disease. Romana sign is associated with ipsilateral regional lymphadenopathy. History and etymology It is named after Cecilio Felix Romana 1899 - 1997, Argentinian physician, who first described the phenomenon. 