<prompt> A 5 year old female patient complains of deformed shape of legs. Patient is a strict vegetarian. Lab investigations reveal elevated levels of alkaline phosphatase. This patient is suffering from deficiency of a vitamin whose recommended dietary allowance is-300IU400IU500IU600IU  <response>: Deficiency of vitamin D causes rickets in children and osteomalacia in adults. The weight bearing bones are bent to form bow-legs. In rickets, the plasma level of calcitriol is decreased and alkaline phosphatase activity is elevated. The daily requirement of vitamin D is 400IU or 10 mg of cholecalciferol.Satyanarayana- Biochemistry, 3rd edition, pg-127 