<prompt> All of the following are decreased in nephrotic syndrome, except -Serum transferrinSerum fibrinogenSerumceruloplasminSerum albumin  <response>: Ans. is b i.e., Serum Fibrinogen o Fibrinogen level is increased in nephrotic syndrome dt increased hepatic synthesis of fibrinogen,o The largest proportion of protein lost in urine is albumin.o Sometimes, globulins can also be excreted -Immunoglobulin excretion increases the susceptibility of infection.o Other proteins which are decreased - Transferrin-Microcytic hypochromic anemia. Cholecalciferol binding protein-hypocalcemia Thyroxine binding globulin-decreased thyroxine level. Antithrombin III-hypercoagulability Ceruloplasmin Causes of Hypercoagulability in nephrotic syndromeo Loss of anti thrombin IIIo Increased synthesis of fibrinogen by liver,o Altered activity of protein C and So Increased platelet aggregability.o Hypercoagulability can cause renal vein thrombosis. 