<prompt> Best treatment for massive pulmonary embolism:Intravenous tissue plasminogen activatorHeparinPulmonary thrombo-embolectomyLow molecular weight heparin warfarin  <response>: Ans. A. Intravenous tissue plasminogen activator Massive pulmonary embolism is best managed by thrombolysis using tissue plasminogen activator. In case thrombolysis is contraindicated then in these patient fogarty catheter removal of clot in pulmonary artery would be done. In submassive pulmonary embolism heparin is used. Chronic pulmonary embolism leading to pulmonary- hypertension known as chronic thromboembolic hypertension is treated with a surgical Procedure known as a pulmonary thromboendarterectomy 