<prompt> All of the following variables can predict survival in a patient with primary sclerosing cholangitis; exceptSerum bilirubin levelSplenomegalyPresence of AMA Antimitochondrial antibody in high titreHistologic stage  <response>: Primary sclerosing cholangitisThe prognosis is unfavorable, with a median survival of 9 to 12 years following the diagnosis, regardless of therapy.Four variables age, serum bilirubin level, histologic stage, and splenomegaly predict survival.The diagnosis is supported by a positive AMA test.The presence of AMA in high titre is unrelated to the clinical or histologic picture. 