<prompt> Aldosterone exes action onProximal tubuleEarly Distal tubulesLoop of HenleCollecting duct  <response>: Aldosterone acts on the late DT and CD cells by combining with an intracellular mineralocoicoid receptor - induces the formation of aldosterone-induced proteins AlPs which promote Na reabsorption by a number of mechanisms and K secretion. Aldosterone AL penetrates the cell from the interstitial side and combines with the mineralocoicoid receptor MR. The complex translocates to the nucleus-promotes gene mediated mRNA synthesis. The mRNA then directs the synthesis of aldosterone-induced proteins Alps. The AlPs activates Na channel, translocate Na channels from cytosolic site to the luminal membrane and NaKATPase of the basolateral membrane, increase ATP production by mitochondria. All these changes promote Na reabsorption-more Kvand H is secreted indirectly Essentials of Medical Pharmacology, K.D Tripathi,6tth edition, page 570 