<prompt> The number of molecules of ATP produced by the total oxidation of acetyl CoA in TCA cycle is681012  <response>: There are 3 NADH molecules generated during one cycle, each of them will give rise to 2 12 ATPs on oxidation by electron transport chain ETC; so altogether they will give 3 × 2 12 7 12 7.5 high energy phosphates. The FADH2 will generate 112 molecules of ATP. In addition, one molecule of GTP equivalent to one molecule of ATP is formed by substrate level phosphorylation. Hence, per turn of the cycle, 10 high energy phosphates are produced.Reference: Vasudevan 7th ed, pg 250 