<prompt> Maternal serum Alpha-fetoprotein is raised in all the following conditions EXCEPT:Spina bifidaMultiple pregnancyOmphaloceleDowns syndrome  <response>: Ans. D. Downs syndromeCauses of Raised MSAFPa. Upper GI obstructionb. Wrong dates under-estimationc. Obstructive uropathyd. NTDe. Feto-maternal haemorrhagef. Congenital nephrosisg. CAML Cystic adenomatoid malformation of the lungh. Placentalcord tumorsi. Sacrococcygeal teratomaj. Multiple pregnancyk. Maternal liver diseasel. Male fetuses have higher MSAFPm. Abdominal wall defectsn. Afro-Caribbean ethnic backgroundo. Associated with increased risk of IUDPPROMIUGRoligohydramniospre-eclampsiap. Smoking 