<prompt> A leukemic patient develops disseminated intravascular coagulation. Examination of the marrow reveals hypergranular promyelocytes, some of which contain multiple Auer rods. The diagnosis of acute promyelocytic leukemia is made. Which of the following translocations is associated with the development of this disorder?t 4;11t 6;9t 8;14t 15;17  <response>: Acute promyelocytic leukemia M3 by the FAB classification is associated with a t15;17 q22;q11 translocation. Disseminated intravascular coagulation can occur in this disorder due to the release of procoagulant substances from the leukemic cells, especially during treatment. The t4;11q21;q23 translocation is associated with acute lymphocytic leukemia ALL and undifferentiated leukemia. The t6;9p23;q34 translocation is found in subtypes of AML with basophilia M1, M2, M4. Burkitts leukemia, which is related to Burkitts lymphoma, is associated with t8;14 q 24;q32. The t8;21 q22;q22 translocation choice D is seen in M2 leukemia, also known as acute myeloid leukemia AML with maturation, and some M4 AML with granulocytic and monocytic maturation. 