<prompt> Lebers amourotic optic neuropathy inheritance isMutation in mitochondrial DNAAutosomal DominantX-linked recessiveAutosomal Recessive  <response>: Ans. a. Mutation in mitochondrial DNALeber hereditary optic neuropathy LHON is rare ganglion cell degeneration.Papillomacular bundle is particularly affected in this case.The condition is caused by maternally inherited mitochondrial DNA point mutations, most frequently 50-90 at nucleotide position 1178 G to A in theMT-ND4 gene.Most commonly affects age group 15-35 years. 