<prompt> Which one of the following is the most appropriate drug to use for the patient described in parentheses?Captopril 60-year-old woman with diabetic nephropathyNitroprusside 50-year-old man with BP of 140195Losartan 29-year-old pregnant womanPropranolol 40-year-old patient with peripheral vascular disease  <response>: ACEIs slow the progression of diabetic nephropathy and are indicated for management of HTN in such patients. Nitroprusside is used IV in severe HTN or hypertensive crisis, not for management of mild-to-moderate HTN. Losartan, which blocks AT-1 receptors, is associated with teratogenic effects during fetal development, as are the ACEIs. Nonselective beta blockers are not ideal for patients who suffer from peripheral vascular disease, diabetes, or asthma. Reserpine causes the release of amines from tumor cells, exacerbating HTN in pheochromocytoma. 