<prompt> The thresholds for permanent sterility in women for prepubeal exposure and premenopausal exposure conditions are1 Gy and 0.2 Gy, respectively6 Gy and 2 Gy, respectively12 Gy and 2 Gy, respectively0.5 to 2 Gy and 20 Gy, respectively  <response>: In women, radiation is highly effective at inducing permanent ovarian failure, but there is a marked age dependence insensitivity. The dose required to induce permanent sterility varies from 12 Gy 1,200 rad prepubeal to 2 Gy 200 rad premenopausal. Pronounced hormonal changes, comparable to those associated with the natural menopause, accompany radiation-induced sterilization in females.Reference: Eric J Hall Textbook of Radiobiology for Radiologist; 5th edition 