<prompt> The most common enzyme deficiency in man is ?Glucose-6-phosphate dehydrogenaseGlucose-6-phosphataseHexokinaseGlucose-1.6-diphosphatse  <response>: A i.e. Glucose-6- PO4 dehydrogenaseGlucose 6 phosphate dehydrogenase deficiency is most common and pyruvate kinase deficiency is 2.d most common cause of enzyme deficiency related hemolytic anemiaQ. 