<prompt> Most potent form of Cannabis indica?CharasGanjaMajoonBhang  <response>: Ans. A. Charas. Ref. FMT by Dr KS Narayan Reddy 29thpg. 543.Cannabis indica or sativa CNS STIMULANT- Indian Hemp. It is a psychoactive drug. All parts of plant contain active principle except stem, root, and seeds. The principle constituient of the resin are cannabinol, which has no action, cannabidiol is also inert, but on exposure to heat it is partly converted to THC. The primary active principle of Cannabis is Tetra-hydro-cannabinol THC.6 It is used in following forms:- 1. Siddhi or Bhang or sabji-- from dried leaves and fruit shoots.- Mildest and contain 15 of active principle.- Fatal dose: 10gkg.6- 2. Majoon -- sweet prepared with Bhang.- Increases appetite and sex desire.- 3. Ganja marihuana-- from flower tops of the female plant.- contain 15-25 of active principle.- Used for smoking in cigarettes, which contain 0.3-0.6 g cannabis and are known as Reeferjoint.- Fatal dose: 8 gkg 6- 4. Charas or Hashish-- It is the resin dope or shit.- Contains 25 - 40 of the active principle.6- Fatal dose: 2 gkg 6 Fatal dose:- THC 30 mgkg. Intoxication:- Feeling of detachment, clarity, cleverness, disinhibition, depersonalisation, euphoria, elation, relaxation, well- being, dreaminess, sleepiness, jocularity, laughing, rapidly changing emotions.- Irrelevant though processes.- Sensory novelty and increased,awareness of stimuli.- Speech changes.- Bad trip: due to distortion of perception, the users feel that they could fly from high windows or stop passing buses with bare hands.- Increased appetite and thurst, tachycardia, restlessness, dry mouth, urinary frequency, injected conjunctiva. Rx:- Stomach wash or emesis.- 100 ml of 50 glucose, 2 mg naloxone, and 100 mg thiamine i.v.- 5-10 mg diazepam if violent.- If flashbacks occur give anti-anxiety and if required anti-psychotic like haloperidol. Chronic poisoning:- In chronic Cases the patient may run amok i.e he develops a psychic disturbance marked by a period of depression, followed by violent attempts to kill persons impulse to murder. In the end he may kill himself or surrender voluntarilyAdditional Educational points: Q.Ans.1Cannabis is chronic users leads toRun Amok2Cocaine leads toFormicationMagnans symptoms or Cocaine Bugs.3Speed ball isCombination of cocaine heroin.4Rave drugEcstasy Methylenedioxymthamphetamine MDMA.5Road poisonDhatura delirient poison.6Cardiac PoisonsNicotine, digitalis, oleander, quinine, aconite mitha zeher and Cyanide.7Strychnine is an example ofSpinal Poison.89Ergotism is called asMnemonic for Atropine toxicity featuresSt.Anthonys Fire - burning pain in limbs. Hot as a Hare Blind as a bat Dry as a bone Red as a beet Mad as a Hen. 