<prompt> LCAT deficiency increases the followingChylomicronsIDLVLDLHDL  <response>: HDL is synthesized and secreted from both liver and intestine Lecithin:cholesterol acyltransferase LCAT activity is associated with HDL containing apo A-I. As cholesterol in HDL becomes esterified, it creates a concentration gradient and draws in cholesterol from tissues and from other lipoproteins thus enabling HDL to function in reverse cholesterol transpo Absence of LCAT leads to block in reverse cholesterol transpo. HDL remains as nascent disks incapable of taking up and esterifying cholesterol. Ref:- Harper 30e; pg num:- 249, 272 