<prompt> Sister Mary Joseph nodule is most commonly seen with: March 2011Ovarian cancerStomach cancerColon cancerPancreatic cancer  <response>: Ans. B: Stomach cancer Gastric tumour may spread the abdominal cavity to the umbilicus Sister Josephs nodule Sister May Josephs nodule: Periumbilical nodule hard mass Represents metastatin involvement of the paraumbilical nodes from intrapelvic or intraabdominal malignancies Seen with: - Stomach - Large bowel - Ovary - Pancreatic tumour Indicates poor prognosis 