<prompt> What constitutes malpighian layerStratum lucidumStratum spinosumStratum granulosumStratum spinosum and basale  <response>: Stratum basale stratum spinosum malphigian layer Layers of the epidermis : Stratum basale: Deepest layer. Single layer of columnar cells on the basal lamina aka germinal layer - produces Keratinocytes Stratum spinosum: Several layers of polygonal keratinocytes attached to one another by desmosomes responsibly for Spiny appearance Stratum granulosum: Few layers of flattened cells that are characterised by deep staining granules of keratohyalin in their cytoplasm. Stratum lucidum: This layer appears homogenous with indistinct cell boundaries tracts of flattened nuclei. Present in areas of thick skin. Stratum corneum: Acellular layer made up of flattened scale like elements containing keratin filaments embedded in protein. 