<prompt> First retinal abnormality in diabetic retinopathy: PGI Dec 2007MicroaneurysmHard exudatesSoft exudatesCotton Wool spots  <response>: Ans. A Microaneurysm Ref Khurana 4th260-62; Parson 20th294-98The earliest detectable lesion is microaneurysms in the macular area -Khurana 4th260Diabetic Retinopathy: Classification- 4 types Khurana 4th260-62Non-proliferative Diabetic RetinopathyMicro aneurysmQ in macular area the earliest detectable lesionQRetinal haemorrhage both deep dot blot haemorrhage superficial haemorrhages flame shapedHard exudateQRetinal oedemaCotton-wool spotQProliferative Diabetic RetinopathyPDR develops in 50 of cases after about 25 years of the onset of diseaseThe hallmark Q of PDR is the occurence of neovasculari- ationi over the changes of very severe NPDRVitreous detachment vitreous haemorrhage may occurDiabetic MaculopathyMacular edemaQ is termed as clinically significant macular edemaChanges in macula affect visionD.Maculopathy-4 subtypeFocal exudative maculopathyDiffuse exudative maculopathyIschaemic maculopathyMixed maculopathyAdvanced Diabetic Eye DiseasePersistent vitreous haemorrhageTractiona! retinal detach m entQNeovascularglaucoma Q 