<prompt> A one year old child presents with sho stature, lethargy, constipation. Clinical examination shows a palpable goiter. Laboratory investigations revealed a low T4 and elevated TSH which of the following is the most likely diagnosis.Thyroid DyshormonogenesisThyroid DysgenesisCentral HypothyroidismTSH Receptor Blocking Antibody  <response>: Child with presence of a palpable goitre ,along with clinical and laboratory features of hypothyroidism suggests a diagnosis of thyroid dyshormonogenesis from the options listed in the question. Ref: Pediatrics By Lloyd J. Brown, Lee Todd Miller page 168. 