<prompt> The marker for determining efficacy of hepatitis B vaccination is:HBs AgIgM Anti HBcIgG Anti HBcAnti - HBs Ag  <response>: Answer is D Anti-HBs Ag Anti-HBsAg is the only serological marker to appear after immunization with hepatitis vaccine. Diagnostic interpretation Hbs Ag Anti Hbs Anti HBc Hbc Ag Anti Hbe Immunization with Hbs Ag - - - - ? Hepatitis B is remote past ? False positive Isolated Anti-HBs Ag in serum is seen in immunization with HBs Ag. Possible Causes of Isolated Anti-HBsAg Positivity in serum Other markers negative hnnumization with 11BsAg after vaccination Hepatitis B in the remote past ? False-positive 