<prompt> Oxygen affinity decreases inHypoxiaHypothermiaHbFIncrease in pH  <response>: Factors that shift O2- Hb dissociation curve to right - ie. Decrease O2 affinity with Hb: ed in H cone. pH, Bohr effect ed CO2 O2, Hypoxic condition ed in temperature. ed DPG. Factors that shi O2-Hb dissocia on curve to the left side ie. increase the O2 affinity with Hb Just reverse of the right shift in temperature Hypothermia in pH 7.6 HbF fetal Hb CO poisoning 