<prompt> 80 year old, asymptomatic man present with a total leucocyte count of I lakh, with 80 lymphocytes and 20 PMCs. What is the most probable diagnosis?HIVCMLCLLIMN  <response>: Chronic lymphocytic leukemia occurs more commonly in middle older age groupsover 50 years of age.Clinical features include anemia,enlargement of superficial lymph nodes,splenomegaly hepatomegaly,hemorrhagic manifestations,susceptibility to infections . Blood picture shows marked leukocytosis50,000-2,00,000microlitre. Usually ,more than 90 of leukocytes are mature small lymphocytes. Reference:Harsh mohan textbook of pathology sixth edition pg no 375 