<prompt> Patient on typical antipychotic develops restlessness typically of the lower limbs. Drug to treat this side effect is-PropranololTrihexiphenoydolQuetiapineDatrolene  <response>: Ans. is a i.e., Propranolol o This side effect is akathasia - Restlessness, feeling of discomfort, apparent agitation manifested as a compelling desire to move about, but without anxiety,o Treatment of choice is beta blockers - PropranololPatient is on antipsychotico Within 1-5 dayso Spasm of muscle ofy Tongue Protrusion, twistingy Face grimacingy Neck torticollisy Jaw trismusy Rye oculogyric crisisy Spine opisthotonusy Abnormal postureo Within 4 weeks 1-4 weekso Restlessness inability to sit or stand quieto Persistent desire to move abouto Fidgety movementso Rocking movemento Within 1-4 weekso Bradykinesiao Rigidityo Tremero Mask facieso Shuffling gaito Within weekso Marked muscular rigidityo High fevero Autonomic instability HR BP, sweatingCPKo Myoglobinemiao Leukocytosiso Disturb consciousnesso Catatonia stuporo Drug is taken for 3 monthso Within 4 weeks of withdrawalo Involuntary movement of facial limb musclesy Chewing, poutingy Puffing of cheeksy Lips lickingy Choreoathetoid movementso After months to yearso Perioral tremerAcute muscular dystoniaAkathisiaParkinsonismNeuroleptic malignant syndromeTardive dyskinesiaPerioral tremer rabbit syndromeo Treatment of choice -o TOC - b-blockers central anticholinergico TOC - central - anticholinergicso DOC - Dantrolene 