<prompt> TH1 is involved in w hich type of hypersensitivity?Type 1Type 2Type 3Type 4  <response>: Delayed type of hypersensitivity is mediated by T cell dependant effector mechanisms involving both CD4 TH1 cells and CD8 Cytotoxic T cells. Antibodies do not play a role in type IV hypersensitivity reactions. The activated TH1 cells release Cytokines that will cause accumulation and activation of macrophages which will cause local damage. TH 2 cells release IL-4 and are involved in Type 1 Hypersensitivity reaction. 