<prompt> Failure of the choroid fissure to close results inCongenital detached retinaCongenital aniridiaCongenital aphakiaColoboma iridis  <response>: Failure of the choroid optic fissure to close results in a cleft of the iris--called coloboma iridis mostly in inferonasal position. This defect may extend into the ciliary body, choroid, optic nerve, or retina. Congenital aphakia--absence of the lens--may result from defective development of the lens placode. 