<prompt> Which of the following is HMB45 negative?MelanomaAngiomyolipomaTendon clear cell sarcomaJuxtaglomerular tumor  <response>: D i.e. Juxtaglomerular tumorRef: Dab Immunohistochemistry Basics, HMB45Explanation:HMB 45: Human Melanoma Black: Positive staining is seen in:Melanoma 85-90, see exceptions under negative staining.Angiomyolipoma.Clear cell sarcoma of soft tissue.Clear cell sugar tumor.Epithelioid sarcoma occasional.Kidney: t6;11p21;q12 renal cell carcinoma.Lymphangioleiomyomatosis also stains non-proliferative cells.Melanocytosis.PEComa.Pheochromocytoma.Pigmented neural tumors some, including some nerve sheath tumors, some neurofibromas pigmented neuroectodermal tumor of infancy.Tuberous sclerosis complex components. 