<prompt> All are true about starting of beta-blocker therapy in a patient with congestive heart failure except:They should be started with optimum dosesThey should be gradually increased over weeksSpecial precautions should be taken in cases of NYHA class III and IVCarvedilol and metoprolol are the preferred drugs.  <response>: Clinical use of β2 adrenergic receptor antagonists in heart failureThese are now recommended for routine use in patients with an ejection fraction 35 and NYHA class II or III symptoms in conjunction with ACE inhibitor or angiotensin-receptor antagonist, and diuretics.These should be initiated at very low doses, generally less than one-tenth of the final target dose.NYHA Class IIIB and IV patients should be approached with a high level of caution; and in recently decompensated heart failure, beta-blockers should not be used until the patients are stabilized for several days to weeks. 