<prompt> The pharmacokinetics of Paroxetine include its ability to be easily absorbed after oral administration in healthy volunteers even after food is ingested. Which of the following is TRUE?Main poion of the medication resides in system circulationLittle of the medication is absorbed into the tissuesLess than 1 of the drug is in systemic circulation owing to extensive distribution in body tissues.Less than 25 is eliminated by the kidneys  <response>: The major poion of paroxetine is distributed into the tissues and less than 1 if in systemic circulation while 64 if eliminated by the kidneys and 36 in the feces. The primary effect is believed to be on brain neurons because of its qualities as a selective serotonin reuptake inhibitor SSRI. Ref: Pollock B.G., Semla T.P., Forsyth C.E. 2009. Chapter 63. Psychoactive Drug Therapy. In J.B. Halter, J.G. Ouslander, M.E. Tinetti, S. Studenski, K.P. High, S. Asthana Eds, Hazzards Geriatric Medicine and Gerontology, 6e. 