<prompt> Which among the following is an antibiotic agent that penetrates burn eschar to reach interface with patients ble tissue ?Mafenide acetateNeomycinSilver nitrateSilver sulfadiazine  <response>: Mafenide acetate Antibiotic agent that penetrates burn eschar to reach interface with patients ble tissue. Disadvantages- Quite painful on any paial thickness areas, and it is a carbonic anhydrase inhibitor that interferes with renal buffering mechanisms. Chloride is retained metabolic acidosis can occur. For these reasons, silver sulfadiazine is more commonly used in burn centers unless a major problem with burn wound sepsis is present. 