<prompt> What is the most likely cause of these skin changes?Asteatotic eczemaChronic venous stasisNecrobiosis lipoidicaPretibial myxedema  <response>: Answer B. Chronic venous stasisThe chronic changes of dependent edema with hyperkeratosis, papillomatous plaques, and loosely adherent crust and cobblestone-like nodules is most consistent with chronic venous stasis, and is known as elephantiasis nostras verrucosa. 