<prompt> Which of the following drug inhibits the enzyme of initial step of cholesterol synthesis ?LovastatinGemfiberozilProbucolCholestyramine  <response>: Ans. is a i.e., Lovastatin o Statins Lovastatin competitively inhibit the conversion of HMG-CoA to mevalonate rate limiting step in cholesterol synthesis by inhibiting the enzyme HMG-CoA reductase. 