<prompt> Which of the following is a quantitative defect in globin synthesis-ThalassemiaSickle cell hemoglobinopathyG6PD deficiencyDiamond-Black fan syndrome  <response>: Ans. is a i.e., Thalassemiao Thalassemia is defined as a Quantitative defect in synthesis of structurally normal elobin chains.Sickle Cell Disease represents a qualitative defect in synthesis of globin chains Structurally abnormal globin chains. G6PD Deficiency and Diamond-Blackfan Syndrome Pure Red Cell Aplasia are not associated with quanitative or qualitative defects in globin chain synthesis 