<prompt> Not true regarding Waldenstrom;s macroglobulinemia,Lymphadenopathy is usually presentBlood viscosity increasedIg M immunoglobulin increasedHypercalcemia  <response>: WALDENSTROMS MACROGLOBULINEMIAIt is a malignancy of lymphoplasmacytoid cells that secreted IgM. In contrast to myeloma, the disease was associated with lymphadenopathy and hepatosplenomegaly, but the major clinical manifestation was hyperviscosity syndrome.Reference: Harrison;s principles of Internal Medicine; 19th edition; Chapter 136 Plasma Cell Disorders 