<prompt> Somatostatin is produced by:A cellB cellD cellF cell  <response>: Ans: c D cell Ref: Robbins, 7th ed, p. 1189Alpha cell-GlucagonsBeta cell-insulinD cell-somatostatinF cell-pancreatic polypeptideSomatostatinomaVIPomaMost common site - Head of pancreasOther names - Vemer Morrison syndrome. Water diarrhea syndrome, WDHA syndromeClinical features - Diabetes mellitus - Gall bladder diseasePancreatic cholera- DiarrhoeaMost common site - Tail of pancreas- SteatorrhoeaClinical features - Watery diarrhea - Hypokalaemia- Hypochlorhydria- Metabolic acidosis- Hypercalcaemia- hyperglycaemiaInsulinomaIt is an endocrine tumour of beta cells. Only 5-15 are malignant.Most common site of Insulinoma -distributed equally all over pancreasWhipples triad1 Symptoms consistent with hypoglycaemia2 A low plasma glucose concentration3 Relief of symptoms after the plasma glucose level is raisedThese features are typically seen in insulinoma. 