<prompt> Wilms tumour is associated with all the following exceptAniridiaBeck with syndromePolycystic kidneyHemihypertrophy  <response>: C Polycystic kidney 617- Ghai 8thWilms tumor is not associated with polycystic kidney disease.Wilms tumor is associated with three distinct syndromes.WAGR syndromeBeckwithQ Wiedemann syndromeDenys-Drash syndrome Wilms tumor Aniridia Genital abnormalities Mental Retardation Enlargement of body organs Hemihypertrophy Renal medullary cysts Adrenal cytomegaly; Abnoraml large cells adrenal cortex Gonadal dysgenesis Male pseudo-hermaphrodite Nephropathy leading to Renal failureMore about wilms tumor also ka Nephroblastoma: Wilms tumor is the most common renal neoplasm 2nd most common malignant abdominal tumor, in children Most common abdominal malignant tumor is neuroblastoma Peak indidence is between 2 and 5yrs of age. 5-10 are bilateral; either both kidneys are involved simultaneously synchronous or one after the other metachronousClinical features of W.T.- Abdominal mass most common presenting feature- Abdominal pain- Vomiting- Hematuria- HypertensionTreatmentHigh cure rates of 80-90 can be achieved with multimodality treatment using surgery, chemotherapy radiotherapy.Surgical resection is done in all stages followed by chemotherapy stage I II or chemotherapy radiotherapy stage III, IV, V.Pre op chemotherapy is given in inoperable bilateral.Chemotherapeutic agents used are Vincristine, Dactinomycin cyclophosphamide. The most important determinants of prognosis is wilms tumour is Histology and stages of disease The treatmet of choice for stage Iwilms tumor is Transperitoneal Radical Nephrectomy Radical Nephroureterectomy followed by chemotherapy with or without radiotherapy depending on tumor histology Surgery is very important in the treatment of all stages of wilms tumor to provide local control and prevent metastatis spread Radical nephrouretectomy is recommended in all patientsFeaturesNeuroblastomaWilms tumorCommon tumorMC intra-abdominal solid tumor in childrenMC renal tumor in childrenAt the time of DiagnosisAlready metastasis in greater then 50 of patientsGenerally confined to the kidneyEncassement of aortaCharacteristicUncommonLung metastasisRareCommonCalcificationCommonRare 