<prompt> A child presents with Hepatosplenomegaly, Abdominal distension, Jaundice, Anemia and Adrenal calcification. Which of the following is the Diagnosis?Adrenal hemorrhagePheochromocytomaWolmans diseaseAddisons disaease  <response>: Wolman disease is caused by mutations in the lysosomal acid lipase LIPA gene and is inherited as an autosomal recessive trait.Wolman disease is the most severe expression of LAL deficiency; a milder form of LAL deficiency is known as cholesteryl ester storage disease CESD. 