<prompt> Drug of choice for precocious puberty in girls is:GnRH analogueDanazolCyproterone acetateMedroxy progesterone acetate  <response>: Ans. A GnRH analogueRef: Harrison 19th2380, KDT 8e p264Long-acting gonadotropin releasing hormone GnRH agonists are the current therapy of choice for central precocious puberty. In girls, mostly central precocious puberty is seen.GnRH agonists are not effective as therapy for peripheral precocious puberty. Androgen antagonists, spironolactone, aromatase inhibitors Anastrozole and Letrozole, ketoconazole, and medroxyprogesterone acetate are used to treat peripheral precocious puberty. 