<prompt> In cholera epidemic which step should be first taken:Vaccination to all individuals immediatelyPrimary chemoprophylaxisCure with tetracyclineSafe water supply and sanitation  <response>: Ans. d Safe water supply and sanitationRef K. Park 23rded. 232-33 Cholera is an acute diarrheal disease caused by Vibrio cholerae. I.P.-1-2 days First step in epidemic of cholera: Verification of diagnosis First line treatment of choice: water and electrolyte replacement. In the given question, safe water supply and sanitation should be the 1st step to decrease mortality from cholera.Also know Stool appearance of cholera: Rice watery stool Chemoprophylaxis of cholera: Tetracycline 500mg BID for 5 days. Drug of choice for cholera: Adults: Doxycycline 300 mg stat. Children: Cotrimoxazole 5mgkg BID for 3 days Pregnant female: Furazolidone 100mg QID for 3 days. 