<prompt> Disulfiraim and acamprosate are used for:Alcohol abstinenceCocaine abuseOpium poisoningAtropine over dose  <response>: Disulfiram inhibits the enzyme aldehyde dehydrogenase probably after conversion into active metabolite .When alcohol is ingested after taking disulfiram the concentration of acetaldehyde in tissue blood rises number of highly distressing symptoms produced. Disulfiram aversion therapy is indicated in abstinent subjects. Ref KD Tripathi 8th ed. 