<prompt> b-blockers act in glaucoma by -Decreased aqueous productionIncreased aqueous outflowReduce vitreous volumeNone  <response>: Ans. is a i.e., Decreased aqueous production Mechanism of action of pharmacological agents in POAGAgentMechanism of actiono b-blocker Timolol. Betaxolol, levobunolol, carteololo Decreased aqueous secretion from ciliary epitheliumo Prostaglandins latanoprost, bimatoprost, travoprosto Increased uveosclerai aqueous outflowo Alpha agonists Non-selective Epinephrine, Dipivefrine Selective a-2 Aprocionidine, BrimonidmeIncreased uveosclerai aqueous outflow.Decreased aqueous secretiono Carbonic anhydrase inhibitors Dorzolamide, Brinzolamide, Acetazolamideo Decreased aqueous secretion due to lack of HCOto Cholinomimetics Pilocarpine, physostigmine. carbachot, echothiphateo Increased aqueous outflow due to opening of trabecular meshwork due to ciliary muscle contractiono Hyperosmotic agents Mannitol, glycerolo Reduce vitreous volume and deepen anterior chamber 