<prompt> A 25 year old male presnents with weakness, occasional vomiting hypotension, skin and mucous membrane pigmentgation. The diagnosis can be best established by -Metyrapone testBasal plasma Coisol levle24-hour urinary 17-KetosteroidACTH stimulation test  <response>: after administration of ACTH , coisol level increases. This can be used as an index of the functional reserve of adrenal gland for production of coisol Harrison 17 pg 2252 