<prompt> A 55-year-old diabetic Raj from Mumbai has a long history of renal failure. He is currently waiting for an organ for transplant and has been on hemodialysis in the interim. If this man develops amyloid deposits around his joints, they are likely to be composed of which of the following substances?Amyloid-associated proteinAmyloid light chainsBeta2 microglobulinCalcitonin precursors  <response>: Amyloid deposits appear similar by light and electron microscopy, but actually represent a heterogeneous population of proteins that have a common teiary structure forming a beta-pleated sheet. Questions about the type of amyloid seen in different disease states are orites on examinations. Here are two tables to help you out: Systemic amyloidosis: Chronic active diseaseAA amyloid from serum amyloid- associated SAA protein from liver choice AMyelomas and related diseasesAL amyloid from immunoglobulin light chain choice BChronic hemodialysisBeta2 microglobulin related to high plasma levels choice CNephropathic hereditary forms familial Mediterranean feverAA amyloid from SAA choice ACardiomyopathic hereditary forms senile systemic amyloidosisPrealbumintransthyretin Neuropathic hereditary syndromesPrealbumintransthyretin Localized amyloidosis: Senile cardiac amyloidosisAtrial natriuretic peptide-related fibrilsCerebral amyloid in Alzheimer disease, Down syndromeCerebral amyloid in Alzheimer disease, Down syndromeMedullary carcinoma of thyroidCalcitonin precursors choice DIsolated, massive, nodular deposits skin, lung, urogenital tractAL from light chains choice B 