<prompt> Which of the following changes occurs in RBCs of stored blood?Increase in Na K contentDecrease in Na K contentIncrease in Na decrease in K contentIncreased activity of Na - K ATPase.  <response>: Changes in red cells during storage: Changes occur due to decreased metabolism.They are increase in their Na decrease in K concentration due to reduced Na-K pump activity, this results in a net increase in total base and water content of the cells that swell and become more spherocytic. The ATP content decreases and inorganic phosphate content increases. 