<prompt> Which of the following is not true about chromothrypsis?It is associated with chromosome rearrangements termed as chromosome shattering.It is observed in 1 to 2 of cancers as a whole.Associated with inactivation of oncogenes and activation of tumor suppressors.Increased frequency of 25 of osteosarcomas and high frequency in gliomas  <response>: Chromothrypsis Phenomenon by which up to thousands of clustered chromosomal rearrangements occur in a single event in localized and confined genomic regions Involved in cancer 1 -2and congenital diseases. Osteosarcomas and gliomas as well. Chromosome breaks occur within pa or across the entirety of a single chromosome or several chromosomes. Activate oncogenes and inactivate tumor suppressors, thereby expediting the process of carcinogenesis. 