<prompt> Not true about angioneurotic edema ?Pitting edema of face, lips and mucous membraneC1 Esterase inhibitor deficiency can cause itExtreme temperature exposure can provoke itKnown with ACE inhibitors  <response>: Edema of angineurotic-edema is non-pitting.C1 esterase inhibitor deficiency can cause hereditary angioneurotic edema.Angioedema is a well known adverse effect of ACE inhibitors. 