<prompt> True statement about neostigmine aaIt is quaternary Ammonium compoundsIt is metabolized by liverIt can cross blood brain barrierProminent effect on cardiac muscle  <response>: Refer kDT 6e p 101,102 neostigmine is a reversible cholinesterase inhibitor. It is a quaernary ammonium compoundlipid insoluble agent So it doesnt cross blood brain barrier It is paly hydrolysed by serum cholinesterase and paly excreted unchanged by the Kidneys It possesses some agonistic action on Nm receptors 