<prompt> Which of the following is the disorder of purine?HyperammonemiaGoutOrotic acduriaHanop disease  <response>: Uric acid , is the end product of purine catabolism. The most common disorder of purine metabolism is an elevation of uric acid level . Gout : It is due to accumulation of urate crystals in the synol fluid resulting in inflammation leading to acute ahritis. Ref : DM.VASUDEVAN.TEXTBOOK SEVENTH EDITION ; PAGE NO : 566. 