<prompt> What is the risk of recurrence of anencephaly in subsequent pregnancy?1234  <response>: ns. is b i.e., 2 Anencephalyo The incidence of anencephalv is 1 in 1000 pregnancies.o About 70 of anencephalic fetuses are females.o The risk of recurrence of anencephalv in subsequent pres nancy is 2.o Folic acid supplementation has reduced the incidence of neural tube defects by 85.o Folic acid supplementation is given beginning 1 month before conception to about to about 12 weeks of pregnancy. A dose of 4mg daily is recommended. 