<prompt> D-dimer is the most sensitive test for-Pulmonary embolismAcute pulmonary edemaCardiac tamponadeAcute MI  <response>: Robbins Basic Pathology 9th Edition,page no.85 Clotting also sets into motion a fibrinolytic cascade that moderates the ultimate size of the clot. Fibrinolysis is largely carried out by plasmin, which breaks down fibrin and interferes with its polymerization . The resulting fibrin split products FSPs or fibrin degradation products also can act as weak anticoagulants. Elevated levels of FSPs most notably fibrin-derived D-dimers can be used for diagnosing abnormal thrombotic states including disseminated intravascular coagulation DIC , deep venous thrombosis, or pulmonary thromboembolism 