<prompt> The following factors shift the oxygen dissociation curve to the right, exceptHypoxiaAcidosisIncrease in 2, 3-DPGAlkalosis  <response>: Oxygen saturation curve Physiology A curve that describes the relationship between Hb O2 saturation and tension; defined by a sigmoid curve which reflects the interaction of the 4 Hb molecules involved in O2 uptake, transport and release; a right shift of the curve indicates Hb affinity for O2, as occurs in pH ie, acidosis, temperature, PCO2, while a left shift indicates O2 affinity with pH, temperature, 2,3 DPG and PCO2 Right shifts Acidosis, hyperthermia, alveolar hypoventilation, anemia Left shifts Alkalosis, hypothermia, hyperventilation, carboxyhemoglobinemia, hypophosphatemia, fetal Hb. 