<prompt> Neurotoxicity is seen with excess ofVitamin B6Vitamin B12Vitamin B2Vitamin C  <response>: Neurotoxicity is seen with excess of Vit B6. Toxicity of pyridoxine: Pyridoxine is the only water-soluble vitamin with significant toxicity. Neurologic symptoms sensory neuropathy occur at intakes above 200 mgday, an amount more than 100 times the RDA. Substantial improvement, but not complete recovery, occurs when the vitamin is discontinued. Reference: Lippincott Textbook of Biochemistry pg no. 378 