<prompt> Causative organism in acute bacterial endocarditis is -Staphylococcus aureusStreptococcus viridansPneumococcusStreptococcus pyogenes  <response>: Acute osteomyelitis may be : -i. Primary hematogenous:- Organisms reach the bone through the bloodstream.ii. Secondary:- Organism gain energy directly through wound such as in compound fractures or surgical operation,Hematogenous osteomyelitis is the commonest form of osteomyelitis and most common source of bone and joint infection is hematogenous.it is caused most commonly by Staphylococcus aureus.Other causative organisms are streptococcus, pneumococcus, and gram-negative bacilli. 