<prompt> The compound that regulates both glycolysis and gluconeogenesis is:Fructose-1,6-bisphosphateFructose-2,6-bisphosphateCitrateGlucose-6-phosphate  <response>: Fructose 2,6 bisphosphate Potent activator of PFK-1 inhibitor of gluconeogenic enzyme fructose 1,6 bisphosphatase. This helps in reciprocal regulation of glycolysis and gluconeogenesis. 