<prompt> Glucosylceramide is accumulated in -Tay-Sach diseaseKrabbes diseaseGauchers diseaseNiemanm Pick disease  <response>: Ans. is c i.e., Gauchers disease DiseaseEnzyme DeficiencyLipid AccumulatingClinical SymptomsTay-Sachs diseaseHexosaminidase ACer--Glc--GalNeuAc -- Gal NacGM2 GangliosideMental retardation, blindness, muscular weaknessFabrys diseasea-GalactosidaseCer--Glc--Gal-- Gal GlobotriaosylceramideSkin rash, kidney failure full symptoms only in males; X-!inked recessiveMetachromatic leukodystrophyArylsulfatase ACer--Gal-- OSO3 3-SulfogalactosylceramideMental retardation and psychologic disturbances in adults; demyelinationKrabbes diseaseb-GalactosidaseCer-- GalMental retardation; myelin almost absentGauchers diseaseb-GlucosidaseCer-- Gal GlucosylceramideEnlarged liver and spleen, erosion of long bones, mental retardation in infantsNiemann-Pick diseaseSphingomyelinaseCer-- P--choline SphingomyelinEnlarged liver and spleen , mental retardation; fatal in early lifeFarbers diseaseCeramidaseAcyl-- Sphingosine CeramideHoarseness, dermatitis, skeletal deformation, mental retardation; fatal in early life 