<prompt> A 12 year old boy presents with hemetemesis, malena and mild splenomegaly. There is no obvious jaundice or ascitis. The most likely diagnosis isEHPVONCPFCirrhosisMalaria with DIC  <response>: Information in question are:Patient is 12 years maleHematemesis, melena and mild splenomegaly k signs of portal hypertensionNo Jaundice or AscitisSo, the boy in question has portal hypertension.Three most common causes of portal hypertension are:Extrahepatic portal vein obstruction EHPVONon-cirrhotic portal fibrosis NCPFCirrhosis.In cirrhosis, jaundice ascitis are prominent. So, this option is ruled out.Now we are left with EHPVO and NCPF. Both these causes non-cirrhotic portal hypertension, i.e. portal hypertension without signs of liver dysfunction.Both these have similar clinical picture except for the age of presentation.EHPVO is usually seen in young male children 1st and 2nd decade while NCPF is a disease of adults 25-35 years.So, best answer here is EHPVO. 