<prompt> Which of the anti metabolite acts as a antifungal agentPaclitaxel5-Flucytosine 5 FcChlorambucilDecarbazine  <response>: 5-FIucytosine 715, 719-KDT 761-KDT6thFLUCYTOSINE 5-FC - It is a pyrimidine antimetabolite which is inactive as such. It is taken up by fungal cells and converted into 5 fluorouracil and then to 5-fluorodeoxyuridylic acid which is an inhibitor of thymidylate synthesis It is narrow spectrum fungistatic, active against Cryptococcus neoformans, Torula, Chromoblastomyces: and few strains of CandidaAdverse effects- Leucopenia, thrombocytopenia and mild anaemia due to dose dependent bone marrow depression is the major roblem GI disturbances are frequent, Liver dysfunction is mild and reversible. 