<prompt> Murphy sign is seen in: March 2013 gAcute pancreatitisAcute appendicitisAcute cholecystitisAcute esophagitis  <response>: Ans. C i.e. Acute cholcystitis Murphys sign It is useful for differentiating pain in the right upper quadrant. Typically, it is positive in cholecystitis, but negative in choledocholithiasis, pyelonephritis and ascending cholangitis. 