<prompt> One virus particle prevents multiplication of the second virus. This phenomena is -Viral interferenceMutationSupervisionPermutation  <response>: InterferenceIn a mixed or multiple infection of cells, in which infection of a cell by one virus inhibits simultaneous or subsequent infection by another virus is called Interference.The most important mediator of interference is interferon.A high multiplicity of infection inhibits production of its own infectious progeny - autointerferenceViral interference has been applied in the field in Controlling poliomyelitis by live attenuated vaccine. 