<prompt> Restriction endonuclease cleavesDouble stranded DNASingle stranded DNASingle stranded RNAPolypeptide  <response>: Restriction endonuclease Cleaves double stranded DNA at palindromic sites restriction sites 5 --AAGCTT-- 33 --TTCGAA-- 5 A palindromic sequence is a sequence which reads the same backwards as forwards. Found in bacteria Can create sticky ends or blunt ends Restriction endonuclease Sticky ends Blunt ends single-stranded overhangs no overhangs Example - EcoRI Example -SmaI 