<prompt> A neonate with recurrent infection was diagnosed with Kostmann syndrome. Treatment is:G-CSF and HSCTGM-CSFAntithymocyte globulincyclosporineAntithymocyte globulincyclosporine GM-CSF  <response>: Severe congenital neutropenia SCN consists of a group of inherited diseases that are characterized by severely impaired neutrophil counts Diagnosis of SCN requires examination of the bone marrow. Subcutaneous injection of the cytokine granulocyte colony-stimulating factor G-CSF usually improves neutrophil development and thus prevents infection in most SCN diseases. SCN with ELA2 mutation are refractory to G-CSF and may require curative treatment allogeneic hematopoietic stem cell transplantation HSCT. Ref: Dale D.C. 2010. Chapter 65. Neutropenia and Neutrophilia. In J.T. Prchal, K. Kaushansky, M.A. Lichtman, T.J. Kipps, U. Seligsohn Eds, Williams Hematology, 8e. 