<prompt> Not true about thalidomide :Causes phocomeliaNot tested in pregnant animals before introductionStill has restricted clinical useHas no antiangiogenesis action against tumour  <response>: Thalidomide was banned in 1960 because of its teratogenic effect of phocomelia seal-like limbs. It has anxiolytic, adjuvant analgesicantipyretic properties and has been found to counteract cancer-associated cachexia.Its mechanism of action is by suppressing TNF and or by modulating IL-2.Recently it has been reintroduced as an antineoplastic drug due to its anti-angiogenesis action. 