<prompt>  A 60 year old man presented with fatigue, weight loss and heaviness in left hypochondrium for 6 months. The hemogram showed Hb.10gmdL, TLC 5 lakhsmm3, platelet count 4 lakhsmm3, DLC: neutrophil 55, lymphocutes 4, monocytes 2, basophils 6, metamyelocytes 10, myelocytes 18, promyelocytes 2 and blasts 3. The most likely cytogenetic abnormality in this case is -t1;21t 9; 22t 15; 17Trisomy 21 