<prompt> LE cell is seen in -Lupus erythmatosusLupus vulgarisHNPCCMedullaiy carcinoma of thyroid  <response>: Ans. is a i.e., Lupus erythematosus o In SLE, antinuclear antibodies ANPs cannot penetrate intact cells,o However, nuclei are exposed, ANA can bind to them.o In tissues, nuclei of damaged cells react with ANAs, lose their chromatin pattern, and become homogeneous, to produce lupus - erythematosus LE bodies or hemotoxylin bodies,o When these LE bodies are engulfed by phagocytic cells neutrophil or macrophagemonocyte, the phagocytic cells are called LE cells. 