<prompt> All are considered to be poor prognostic factors in liver metastasis exceptSynchronous lesionsMetachronous lesionsExtra-hepatic metastasisCEA200ngml  <response>: Poor prognostic or factors affecting outcome Four or more tumors Extra hepatic disease Size 5cm Disease free interval 1 year Lymph node positive primary lesion CEA 200ng ml Synchronous liver metastasis Ref:Sabiston 20th edition Pgno :1464-1465 