<prompt> Esmolol is a sho acting b blocker becauseIt has more plasma protein bindingIts plasma hydrolysis by esterases is rapidIt has high lipid solubilityIt has high oral bioavailability  <response>: Esmolol - Shoest acting b blocker Nadolol - Longest acting b blocker Esmolol is metabolized by pseudocholinesterase hence it is sho acting. Drugs metabolized by pseudocholinesterase SUCCINYLCHOLINE ESMOLOL REMIFENTANIL 