<prompt> A 44 year old male presents to the OPD with a swelling on the palate. On intraoral examination, marked swelling is seen in the region of palatine papilla, situated mesial to the roots of 11 21. These teeth respond normally to vitality test. IOPA is given below. What is the most probable diagnosis?Globulomaxillary cystRadicular cystCyst of palatine papillaNasopalatine cyst  <response>: Clinical featureThe age distribution is broad, with most cases being discovered in the fourth through sixth decades. The incidence is three times higher in males. Most of these cysts are asymptomatic or cause such minor symptoms that they are tolerated for long periods. The most frequent complaint is a small, well-defined swelling just posterior to the palatine papilla. This swelling usually is fluctuant and blue if the cyst is near the surface. The deeper nasopalatine duct cyst is covered by normal-appearing mucosa, unless it is ulcerated from masticatory trauma. If the cyst expands, it may penetrate the labial plate and produce a swelling below the maxillary labial frenum or to one side. The lesion also may bulge into the nasal cavity and distort the nasal septum. Pressure from the cyst on the adjacent nasopalatine nerves that occupy the same canal may cause a burning sensation or numbness over.Differential DiagnosisThe most common differential diagnosis is a large incisive foramen. A foramen larger than 6 mm may simulate the appearance of a cyst. However, a clinical examination should reveal the expansion. A radicular cyst or granuloma associated with a central incisor is similar in appearance to an asymmetric nasopalatine cyst. The presence or absence of the lamina dura and enlargement of the periodontal ligament space around the apex of the central incisor indicate an inflammatory lesion. A vitality test of the central incisor may be useful. characteristic of a cyst and other changes that occur with a space-occupying lesion, such as displacement of teeth.Oral Radiology, Principles and Interpretation Stuart C. White, Michael J. Pharoah - 7th ed pg-352 