<prompt> Thrombotic thrombocytopenic purpura involves all except?MicroangiopathyNeural dysfunctionHigh complement levelIntravascular hemolysis  <response>: Ans. is c i.e., High complement level Platelet associated IgG and complement levels are usually normal in TTP.Thrombotic thrombocytopenia purpura TTP Moschcowitz disease TTP is included among group of diseases called thrombotic microangiopathies. Small vessels like terminal arterioles and capillaries are involved. Patients with TTP are deficient in an enzyme called ADAMTSB.13 also known as vWF metalloprotease leading to platelet macroaggregate formation throughout the microcirculation.Clinical features TTP is characterized by a pentad of1. Microangiopathic hemolytic anemia2. Thrombocytopenia3. Neurological symptoms platelet thrombin in cerebral vessels4. Renal dysfunction5. Fever There is intravascular hemolysis. BT is raised with normal PT and aPTT. 