<prompt> Casals paint necklace is seen in?Lichen planusPellagraPernicious anemiaSLE  <response>: Pellagra Etiology: Dietary deficiency of nicotinic acid or its precursor tryptophan. People with staple diet - maize and Jowar. Maize is poor source of both nicotinic acid and tryptophan and a pa of nicotinic acid is in a bound form that is not assimilated in GIT. Jowar-has high content of leucine.Imbalance between leucine and other related amino acids interferes with conversion of tryptophan to nicotinic acid. Malabsorption Drugs like INH, 5FU, and 6-mercaptopurine. Carcinoid syndrome Cf: Middle aged persons Pellagra:- Dermatitis,Dementia,Diarrhea,Death Tt: Niacinamide 300-500mgday orally in divided doses. 