<prompt> Recurrent Giardiasis is associated with:Severe combined immunodeficiencyCommon variable immunodeficiencyDigeorge syndromeC8 deficiency  <response>: Common variable immunodeficiency is associated with the deficient production of antibodiesThey have a normal number of B lymphocytes but fail to mature into plasma cellsResults in hypogammaglobulinemia, with a reduction in all classes of Ig but sometimes only IgG is reducedVarious disorders associated:Intestinal disorders:Chronic giardiasisIntestinal malabsorptionAtrophic gastritiswith pernicious anaemiaChronic pulmonary infections:bronchiectasisOthers:can also present with signs and symptoms of lymphoid malignanciesfeverweight lossanaemiasplenomegalylymphadenopathyref: Harrisons 18e p1849, 2059 