<prompt> Anti cancer drug causing nephrotoxicity -CyclophosphamideBusulfanCisplatinProcarbazine  <response>: Ans. is c i.e., Cisplatin Platinum compoundo These are alkylating agents and act by similar mechanism,o Drugs are -First generation-CisplatinSecond generation-CarboplatinThird generation-OxaliplatinSide effects of Cisplatino Vomitingo Ototoxicityo Hyperuricemiao Nephrotoxicityo Neuropathy Note-o Cisplatin is most nephrotoxic where as carboplatin is more hematotoxic bone marrow suppression,o Carboplatin has less nephrotoxic, neurotoxic and ototoxic effects,o Dose limiting toxicity of oxaliplatin is neurotoxicity Peripheral neuropathy. 