<prompt> Regarding opioid induced seizures:They usually occur at therapeutic dosesChildren are more susceptibleSeizures occur only with u-opioid agonistsDiazepam is the drug of choice in treatment  <response>: Controlled-release oxycodone-induced seizures. ... However, opioid-related seizure in patients with epilepsy or other conditions that may decrease seizure threshold has been described in the literature; in paicular, oxycodone has been associated with seizure in a patient with acute renal failure Ref KD Tripathi 8th ed, 