<prompt> A neonate is having jaundice involving palms and soles. The approximate serum bilirubin is4-6 mgdl6-8 mgdl8-12 mgdl15 mgdl  <response>: Serum levels of total bilirubin are approximately 4-6 mgdl Face, 6-8 mgdl Chest and upper abdomen, 8-12 mgdl Lower abdomen and thighs, 12-14 mgdl Arms and legs and 15 mgdl Palms and soles. Yellow staining of palms and soles is a danger sign and requires urgent serum bilirubin estimation and fuher management.In general, the estimation of bilirubin levels by dermal zones is unreliable paicularly at higher TSB levels, after phototherapy and when it is carried out by an inexperienced observer. Total serum bilirubin can be assessed non invasively by a transcutaneous handheld device.Ref: Paediatrics; O.P. Ghai; 8th edition; Page no: 173 