<prompt> Zidovudine given for HIV in preganancy because -Decreases the risk of veical transmissionDecrease severity of infection in motherDecrease seveiy of infection in newbornCauses no benefit  <response>: Ans. is a i.e., Decreases the risk of veical transmission Treatment during Pregnancy HIV infected mother can transmit the virus to fetusinfant during pregnancy, during delivery or by breast feeding. o Early diagnosis and antiretroviral therapy to mother and infant significantly decrease the rate of intrapaum and perinatal transmission veical transmission of HIV infection. o Zidovudine treatment of HIV infected pregnant women from the beginning of second trimester through delivery and of infant for 6 weeks following bih decreases the rate of transmission from 22.6 to 5. o Single dose of nevirapine given to the mother at the onset of labor followed by a single dose to the newborn within 72 hours of bih decreased transmission by 50. This is the prefered regimen now in developing countries. Treatment of HIV infection in general HAA o It includes 3 or more drugs, of which one or two are always NIs. o The combination may be 2 NRITs 1 protease inhibitor or 1NRITs 1NNRITs 1PI. For prophylaxis a combination of two NIs regimen A or a combination of two NRITs plus a protease inhibitor regimen B may be used - regimen B is preffered. 