<prompt> Initial treatment of buphthalmos is -Laser trabeculolastyGoniotomyTopical pilocarpineCarbonic anhydrase inhibitors  <response>: In Buphthalmos medications are not effective and so treatment is primarily surgical. Incisional angle surgery by goniotomy or trabeculectomy Ref:Comprehensive ophthalmology-AK Khurana 6th edition chapter-10 page no:227 