<prompt> Cardiotoxicity induced by Doxorubicin can be reduced by:DexrazoxaneAmifostineLeucovorinBisphosphonates  <response>: Ans. A. Dexrazoxane Cardiotoxicity induced by Doxorubicin is an important side effect which can be modified by the use of Dexrazoxane. Dexrazoxane: Iron chelator that decreases free radical formation Protects myocardium from anthracycline induced injury. Amifostine Radio protective agent Reduces renal toxicity caused by cisplatin Leucovorin: Reduces bone marrow mucosal toxicity caused by methotrexate other measures Mesna: Reduces bladder toxicity caused by Cyclophosphamide. Bisphosphonate: Reduces bone pain frequency of new skeletal events in metastatic breast cancer Multiple myeloma. 