<prompt> Non-functional enzymes are all exceptAlkaline phosphataseAcid phosphataseLipoprotein lipaseGamma glutamyl transpeptidase  <response>: Non-functional plasma enzymes: Present in plasma at lower concentration than tissues Do not have any function in plasma Mostly synthesized by the liver, skeletal muscle, hea, brain etc Usually increased in disease conditions Eg. Creatine kinase, Alanine transaminase etc Measurement of these enzymes in plasma can be used to assess cell damage and proliferation i.e. diagnosis of disease. Functional plasma enzymes: P Functional plasma enzymes: Present in plasma at higher concentration than tissues present in plasma at higher concentration than tissues. They function in plasma. Mostly synthesized by the liver Usually decreased in disease conditions Eg. Clotting enzymes, lipoprotein lipase 