<prompt> Enzyme deficient in Tay-sachs disease :a galactosidaseHexosaminidase Ab galactosidaseb glucosidase  <response>: Ans. b Hexosaminidase ARef: Harpers Biochemistry, 30th ed. pg. 251 Tay-Sachs disease also known as GM2 gangliosidosis or hexosaminidase A deficiency is a rare autosomal recessive genetic disorder. In its most common variant known as infantile Tay- Sachs disease, it causes a progressive deterioration of nerve cells and of mental and physical abilities that commences around six months of age and usually results in death by the age of four. 