<prompt> Chronic thiazide therapy causes persistent hypercalcemia due to :Renal tubular acidosisFanconis syndromeHyper vitaminosis DHyper parathyroidism  <response>: Ans. is d Hyperparathyroidism Chronic thiazide therapy causes hypercalcemia because it enhances the parathyroid mediated increase of Ca reabsorption.Note: Thiazide diuretics cause hypercalcemia where as high ceiling diuretics cause hypocalcemia.Other important side effects of Thiazide diureticsHyperuricemia Hypokalemia More than high ceiling diureticsDilutional hyponatremiaHyperglycemia and HyperlipidemiaMagnesium depletion 