<prompt> A 62-year-old woman with multiple myeloma is given pamidronate calcium biphosphonates. This treatment has been shown to do what?Increase survivalImprove quality of life and protect against skeletal fracturesStimulate osteoclastIncrease hypercalcemia  <response>: In multiple myeloma, pamidronate calcium biphosphonates has been found to be useful as an adjunctive treatment, reducing the incidence of skeletal fractures. 