<prompt> Elongated filaments in Picks disease consist ofHyperphosphorylated tauUbiquitinAlpha-synucleinBeta-synuclein  <response>: Harrisons principles of internal medicine 17th edition. In Picks disease dementia is frontotemporal dementia Molecular basis - tau Causal genes and chromosome - tau exon and intron mutation17 Susceptibility - H1 tau haplophytes Pathology - tau inclusions,pick bodies,neurofibrillary tangles 