<prompt> The combination of trimethoprim and sulfamethoxazole is effective against which of the following oppounistic infections in the AIDS patient?Disseminated Herpes simplexCryptococcal meningitisPneumocystis jiroveciTuberculosis  <response>: Cotrimoxazole is drug of choice for : - Pneumocystis- Nocardia- Burkholderia Cepacia Both sulfonamide and trimethoprime are bacteriostatic when used alone, it becomes bacteriocidal in combine state. Cotrimoxazole is used as a prophylaxis for Pneumocystis Jirovecii pneumonia in immunocompromised individuals like HIV. Aerolized pentamidine, Dapsone, Dapsone plus pyrimethamine, Atovoquone are other drugs which can be used for the same also. Herpes Simplex: DOC is Acyclovir Cryptococcal meningitis: Acute phase: amphotericin BMaintenance phase: Fluconazole Suldoxime Pyrimethamine is used for parasitemalaria and toxoplasmosis 