<prompt> Most common cytogenetic abnormality in Multiple myeloma isDeletion 13qTTT  <response>: Multiple myelomasolitary plasmacytoma: Genotype: Diverse rearrangements involving IgH; 13q deletionsSalient Features: older adults with lytic bone lesions, pathologic fractures, hypercalcemia, and renal failure; moderately aggressive Plasmacytoma: isolated plasma cell masses in bone or soft tissue; indolent Reference: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 13; Disorders of white cells 