<prompt> A biopsy of an enlarged salivary gland from an individual with Sjogrens syndrome is most likely to histologically reveal an extensive infiltrate ofEpithelioid cellsBasophilsLymphocytesNeutrophils  <response>: Sjogrens syndrome is characterized by dryness of the mouth xerostomia and eyes keratoconjunctivitis sicca. Secondary Sjogrens syndrome is associated with rheumatoid ahritis RA, SLE, or systemic sclerosis. The primary form shows increased frequency of HLA-DR3, while association with RA shows a positive correlation with HLA-DR4. Anti-SSB antibodies are fairly specific, antiSSA less so, and both may occur in SLE; rheumatoid factor is often present. Glomerular lesions are very rare, but a mild tubulointerstitial nephritis is quite common and may result in renal tubular acidosis. In addition to the usual dense, lymphoplasmacytic infiltrate of salivary glands, the lymph nodes may show a pseudolymphomatous appearance. True B cell lymphomas have developed with increased frequency in Sjogrens syndrome Reference: Robbins Cotran Pathologic Basis of Disease, 9edition. 