<prompt> Antihypeensive drug that causes coombs test positive isMethydopaClonidineHydralizineSodium nitroprusside  <response>: Refer kDT 6e p547 Methyldopa is known to cause the production of autoantibodies against red blood cells RBCs, leading to apositive direct antiglobulin test DAT and hemolytic anemia. ... Her mother had the history of taking methyldopain her pregnancy. 