<prompt> Basic abnormality in a case of nephrotic syndrome is:September 2008HyperlipidemiaProteinuriaPedal edemaHypeension  <response>: Ans. B: ProteinuriaNephrotic syndrome NS nephrosis is defined by the presence of nephrotic-range proteinuria, edema, hyperlipidemia, and hypoalbuminemia.Heavy proteinuria more than 1 gmmetre square per day is the basic abnormality leading to the hypoalbuminemia serum albumin below 2.5 g dL 