<prompt> IFN-a and IFN-b are produced by the virus-infected cell due to the interaction of virus nucleic acid with which of the following?C3 third component of complementDefensinsTLR pathwayIL-12  <response>: Following virus entry into a cell, the virus initiates replication and the viral nucleic acid interacts with specific microbial sensors TLR3, TLR7, TLR 9, RIG-1, and MDA-5. This interaction triggers cellular production of IFN that is secreted from the infected cell.Jawetz 27e pg: 130 