<prompt> What is implied, if a drug has more renal clearance than the GFR :Drug is reabsorbed in the tubulesDrug is secreted in the tubulesDrug is excreted in bileDrug is neither secreted, nor resorbed.  <response>: Ans. is b i.e. Drug is secreted in the tubules Logically, if a drug is more in renal clearance than the amount filtered by glomerulus, it has to be secreted in the kidney tubules. Tubular secretion - is the active transfer of organic acids and bases by two separate nonspecific mechanism which operate in the proximal tubules. If renal clearance of a drug is greater than 120 mlmin g.f.r., additional tubular secretion can be assumed to be occuring Soif renal clearance is more than G.F.R. - Tubular secretionIf renal clearance is less than G.F.R. - Tubular reabsorption.If renal clearance is equal to G.F.R. - The drug does not undergo either tubular sec. or tub. reabsorption. 