<prompt> The role of plasmids in conjugation was first described by Lederberg and Tatum 1946 in which bacteria?H. influenzaPseudomonasEscherichia coliM. Tuberculosis  <response>: Bacterial conjugation was first described by Lederberg and Tatum 1946 in a strain of E.coli called K12 carried a conjugative plasmid F The F factor: The F plasmid, also called F factor, is a transfer factor that contains the genetic information, essential for controlling mating process of the bacteria during conjugation. The F plasmid of Escherichia coli is the prototype for feility plasmids in Gram-negative bacteria. Strains of E. coli with F plasmid are called as donors, whereas plasmid are F- behave as recipients. 