<prompt> Which of the following is the most sensitive marker of active Hepatitis B virus replication :HBV DNAHBV DNA polymeraseHBeAgTransaminases  <response>: Answer is A HBV DNA HBV DNA is the most sensitive marker of active Hepatitis B virus replication HBV DNA is the most sensitive marker of virus replication. The detection of HBV DNA as the most sensitive marker of virus replication end as such proof of infectivity has replaced the determination of DNA polymerase -- Hepatology by Kuntz 3rd121 The gold standard for confirmation of viral replication is qualitative HBV DNA detection -- Viral Infections Treatment by Weigmann 2003225 Markers for HBV Replication HBV DNAe HBV DNA polymerasee HBe Age 