<prompt> The Ridley-Jopling classification for leprosy is based on which of the following parameters?Clinical, bacteriological, immunologicalHistopathological, clinical, therapeuticHistopathological, epidemiological, therapeuticsHistopathological. clinical, epidemiological  <response>: Ans. a. Clinical, bacteriological, immunological Ref: Fitzpatrick 7th1786-1796; Roxburgh 18th49-50Ridley-Jopling Classification for Leprosy is based on Clinical skin and nerve involvement, bacteriological bacteriological morphological index in skin and nasal smears and immunological criteria Lepromin test.The patient has presented with a single anesthetic patch and single enlarged nerve, and a well-defined granuloma can be seen on the skin biopsy. These findings are typical of Tuberculoid leprosy.FeatureTTBTBBBLLLSkin LesionsNumberSinglefewFewSeveralNumerousInnumerableSizeVariableMaybe largeVariableSmallQSmallQSensationsAnestheticQHypoestheticHypoestheticHypoestheticNormoestheticSymmetryAsymmetricalQAsymmetricalBilateral,AsymmetricalNearlySymmetricalSymmetricalQMorphologyWelt defined macule plaqueWell defined plaques with satellite lesionsPlaques with sloping edge inverted saucer appearanceMacule, nodules, III defined plaquesMacule, nodules, III defined plaquesNervesSingle trunkQAsymmetrical involvement of few nerves with thickeningSeveral nerves involved asymmetrically with thickeningGlove stocking anesthesiaQSymmetrical nerve thickeningQReactionsStableQType IQType IQType IIIType IIQLepromin Test- -HistologyGranulomaWell defined epithelioid cel! granulomasQEpithelioid cell granulomaQ_III-defined macrophage granulomas with many lymphocytesIII-defined foamy macrophage granulomasQGrenz Zone-QQQAFB---Q 