<prompt> Busulfan may cause: September 2007CystitisPulmonary fibrosisLoss of hairPeripheral neuropathy  <response>: Ans. B: Pulmonary Fibrosis Toxicity of busulphan may include: Interstitial pulmonary fibrosis Hyperpigmentation Seizures Hepatic veno-occlusive disease Wasting syndrome. Phenytoin may be used concurrently to prevent the seizures. Levetiracetam, has shown efficacy for the prophylaxis against busulfan-induced seizures. Benzodiazepines can also be used for busulfan-induced seizures. 