<prompt> Which of the following features is shared in common between lymphocyte-rich and lymphocyte-predominant types of Hodgkins lymphoma?Paucity of diagnostic RS cellsEBV is associated in 40 of casesRS cells are CD20 positivePrognosis is excellent  <response>: Ans. d Prognosis is excellent Ref. Robbins 7th689Paragraph from Robbins Pathology 7th ed. p. 688, Table 14-6:Lymphocyte-rich:Lymphocyte predominance: Frequent mononuclear R-S cells0 Paucity of RS cells 40 EBV.Q R-S cells CD20, CD15-, C30-; CD20 and CD 45-Q EBV--Q. Very good to excellent prognosis. Excellent prognosis QPathological features of Types of NHLSubtypeMorphology and immunophenotypeTypical clinical featuresNodular sclerosis Most common type 65-70 R-S cells CD15, CD30; CD 45- Frequent mediastinal involvement, diagnostic R-S cells; EBV-. B and T cell markers- Excellent prognosis Stage 1 or 2 disease most common. Frequent lacunar cells and occasional F M, most patients young adults Background infiltrate composed of T-cells, eosinophils, macrophages and plasma cells with fibrous bands dividing cellular areas into nodules.Mixed cellularity 20-25 Diffuse effacement of nodes Frequent mononuclear and RS cells R-S cells CD15, CD30; Background infiltrate rich in T lymphocytes, eosinophils, macrophages, plasma ceils;- 70 EBV, More than 50 present as stage 3 or 4 disease. M F. Biphasic incidence, peaking in young adults and again in adults 55 yrs.Lymphocyte-rich Uncommon Frequent mononuclear and diagnostic R-S cells; Background infiltrate rich in T-cells R-S cells CD15, CD30; 40 EBV.Q CD20 and CD 45-Q Very good to excellent prognosis. Uncommon. M F. Tends to be seen in older adults.Lymphocyte depletion Least common 5 Reticular variant: Frequent diagnostic R-S cells and variants with a paucity of background reactive cells; diffuse fibrosis variant; Hypocellular fibrillar background with scattered diagnostic R-S cells and variants and few reactive ceils. R-S cells CD15, CD30; Most EBV. Uncommon. More common in older males. HIV-infected individuals, and in developing countries. More likely to present with advanced disease. Less favourable outcome.Lymphocyte predominance Uncommon 5 Frequent Lymphohistiocytic popcorn cell variants in a background of follicular dendritic cells and reactive B cells, Paucity of RS cells R-S cells CD20, CD15-, C30-; EBV-. Excellent prognosis Uncommon. Young males with cervical or axillary lymphadenopathy. Mediastinal. 