<prompt> A 5 yr old boy presented with leukocoria in right eyeball diagnosed to be retinoblastoma involving full eyeball, while other eye had 2-3 small lesions in the periphery. What will be the ideal management for this patient?Enucleation of both eyesEnucleation of right eye conservative management of the other eyeEnucleation of right eye and focal therapy of the other eye6 cycles of chemotherapy  <response>: Enucleation is treatment of choice for group E tumors .involves more than half of retina , optic nerve and AC involved, glucoma present. Ref: ak khurana 6th edition 