<prompt> IP3 facilitates which ion entry into cytoplasm?NaKCaMg  <response>: In the cells, Phosphatidyl inositol Pyrophosphate PIP2 is present in membrane This PIP2 is broken into DAG and IP3 by the enzyme Phospholipase C IP3 being polar will go into cytoplasm and acts as the 2nd messenger Help in releasing calcium stores and increases Calcium levels in the cell. 