<prompt> Adrenogential syndrome is most commonly caused by?21 a hydroxilase deficiency17 a hydroxilase deficiency3 b hydroxilase deficiencySteroid sulfatase deficiency  <response>: ANSWER: A 21 a hydroxilase deficiencyREF: Endocrine Pathology Differential Diagnosis and Molecular Advances edited by Ricardo V. Lloyd page 338REPEAT See APPENDIX-58 for CONGENITAL ADRENAL HYPERPLASIACommon medical termLocusSubstratesProductsMineraloco - rticoidsAndrogens21-hydroxylase CAH90-956p21.317OH-progesterone -progesterone -11-deoxycor-tisolDOC11b-hydroxylaseCAH58q21-2211-deoxycortisol - DOC -cortisolcorticosterone3b-HSD CAHveryrarelpl3pregnenolone -l7OH-pregnenoloneDHEA -progesterone17OH-proges - terone androstenedi - one17a-hydroxylaseCAHveryrare10q24.3pregnenolone - progesterone - 17OH-pregnenolone-17OH-pregne - nolone17OH-proges - teroneDHEAlipoid CAH 20,22-desmolaseveryrare8pll.215q23-q24transport of cholesterolcholesterol -into mitochondriapregnenoloneAdrenogenital syndrome:AKA- Congenita adrenal hyperplasiaTransmitted as autosomal recessive traitExcessive production of adrenal androgensThe adrenogenital syndrome results most commonly from 21-alpha-hydroxylase deficiency with consequent impaired adrenal cortisol synthesis.Adrenogenital syndrome may be inherited congenital adrenal hyperplasia-CAH or acquired adrenal virilism, usually as a result of adrenal tumor 