<prompt> Which of the following is true for acanthosis nigricans:May be an indication of skin malignancyHypopigmentationMay be associated with Insulin resistant diabetes mellitusCommonly occurs in lean and thin  <response>: Ans. C: May be associated with Insulin resistant diabetes mellitus Acanthosis nigricans is associated with obesity and insulin resistance in majority of the patients. In few cases, it may be a reflection of endocrinopathy such as acromegaly, cushings syndrome polycystic ovarian syndrome. It occurs primarily in flexural areas as velvety hyperpigmentation. It may be a reflection of GIT malignancy. 