<prompt> A 28 year old woman underwent a feility sparing surgery for a 6x6 cm granulosa cell ovarian tumour. Which one of the following will you monitor for detection of recurrence?Ca 19-9LDHInhibin BPlacental Alkaline phosphatase PLAP  <response>: GRANULOSA CELL TUMORS NON EPITHELIAL-SEX CORD STROMAL TUMORS Arise from granulosa cells Estrogen secreting functional tumors Presentation: abnormal uterine bleeding, precocious pubey Unilateral Call Exner bodies May cause endometrial hyperplasia and endometrial cancer estrogen excess Treatment: surgery: Unilateral salpingo-oophorectomy for feility sparing Tumor markers: INHIBIN A, INHIBIN B, CA 125, AMH Most commonly raised and most commonly used: INHIBIN B Most specific: AMH 