<prompt> A patient is diagnosed to have CIN II. She approaches you for advice. You can definitely tell her the risk of malignancy as1560305  <response>: CIN I and CIN II, the lesions have a 5-10 chance to progress to a high grade lesion CIN III progressing to cervical cancer is almost 10-30 Transformation Rates Form low grade CIN to High grade CIN takes around 5-6 years From High Grade CIN to invasive cancer takes around 10 years time. HPV related cervical lesions occur more on the cervical anterior lip than the lower lip 2:1 incidence. 