<prompt> The most common lysosomal storage disorder isGauchers diseaseTaysachs diseaseWolman diseaseNiemann picks disease  <response>: Ans. a Gauchers diseaseRef: Harpers Biochemistry, 30th ed. pg. 251LYSOSOMAL STORAGE DISEASE Lyzosomal storage disorders are a group of approximately 50 rare inherited metabolic disorders that result from defects in lysosomal function. Lysosomal storage disorders are caused by lysosomal dysfunction usually as a consequence of deficiency of a single enzyme required for the metabolism of lipids, glycoproteins sugar containing proteins or so-called mucopolysaccharides. Gauchers disease is the most common of the lysosomal storage diseases. It is a form of sphingolipidosis a subgroup of lysosomal storage diseases, as it involves dysfunctional metabolism of sphingolipids. The disorder is characterized by bruising fatigue, anemia, low blood platelets, and enlargement of the liver and spleen. 