<prompt> Tophus is the pathognomonic lesion of which of the following conditionMultiple myelomaGoutCystinosisEales disease  <response>: Tophi are pathognomonic of gout. They are formed by large aggregations of urate crystals. The urate crystals are surrounded bya. Macrophagesb. Lymphocytesc. Large foreign body giant cellsThey are seen in them.Articular cartilages of joints b. Periarticular ligamentsc. Tendons and soft tissuesd. Achilles tendone. EarlobesAlso, remember these very important points related to Gout-Hyperuricemia is present in approximately 5 of individuals. Most of them are asymptomatic with regard to their hyperuricemia and are at no clinical risk.The most recognized complication of Hyperuricemia is Gouty arthritis. The higher the serum level of urate the more likely an individual is to develop Gout.An acute attack of gout occurs without any precipitating cause or may occur following rapid 