<prompt> Net ATPs produced by substrate level phosphorylation when one molecule of fructose is conveed to two molecules of pyruvate?2345  <response>: ATP yield of fructose is same as that of glucose. One may argue that fructose enters glycolysis bypassing the energy investment step fructose-1-phosphate to fructose 1,6 bisphosphate and thus 1 ATP should be obtained extra. but one extra ATP is used for conversion of glyceraldehyde to GAP. So ATP consumption total 2 per fructose is same as glycolysis of glucose. Look at the ATP used in the image when fructose enter glycolysis. Hence Net ATP yield is also 4 ATP produced- 2 ATP used 2 ATPs 