<prompt> Effects of hypokalemia-AcidosisArrhythmiaIleus of intestinePolyuria  <response>: The functional effects of hypokalemia on the kidney can include Na-Cl- and HCO3- retention, polyuria, phosphaturia, hypocitraturia, and an activation of renal ammoniagenesis. Bicarbonate retention and other acid-base effects of hypokalemia can contribute to the generation of metabolic alkalosis Hypokalemia is a major risk factor for both ventricular and atrial arrhythmias Hypokalemia also results in hyperpolarization of skeletal muscle ,thus impairing the capacity to depolarize and contract; weakness and even paralysis may ensue. It also causes a skeletal myopathy and predisposes to rhabdomyolysis. Finally, the paralytic effects of hypokalemia on intestinal smooth muscle may cause intestinal ileus. REF : harrisons principles of internal medicine, 19E, pg 308 