<prompt> Choose the TRUEFALSE statements regarding polycythemia vera: a The JAK2 gene is located on the sho arm of chromosome 12 b Splenomegaly will be the initial presenting sign in PV c Venous and aerial thrombosis may be the presenting manifestation of PV d Red cell mass and plasma volume determinations are mandatory to establish the presence of an absolute erythrocytosis e A bone marrow aspirate and biopsy provide specific diagnostic informationb,c,d-True a,e-Falsea,b,c,e-True d-Falsea,c,d,e-True b-Falseb,c,e-True a,d-False  <response>: The JAK2 gene is located on the sho arm of chromosome 9. A bone marrow aspirate and biopsy provide no specific diagnostic information unless there is a need to exclude some other disorder, these procedures need not be done. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 898, 899 