<prompt> In Raynauds disease true is :Lower limb more commonly involved than upper limbMore common in femaleSup. thrombophlebitisAssociated with migraine  <response>: Ans. is b i.e. More common in female Raynauds disease The diagnosis of Raynauds ds. is made when the secondary causes of Raynauds phenomenon are ruled out. Over 50 of pts. with Raynauds phenomenon have Raynauds ds. Ds. is more common in female M : F ratio is 1 : 5 Age of presentation - 20 to 40 yrs. Fingers are involved more frequently than toes Rarely earlobes and tip of the nose may be involved Raynauds phenomenon occurs frequently in patients who also have migraine headaches or variant angina. These associations suggest a common predisposing cause for the vasospasm On physical examination the pts. are often entirely normal. The radial, ulnar and the pedial pulses are normal. Sclerodactyly thickening and tightening of the digital subcutaneous tissue may develop in few pts. In general, pts. with Raynauds disease appear to have a milder form of Raynauds phenomenon. Fewer than 1 of these patients lose a pa of digit. 