<prompt> Hemolytic anaemia is seen most commonly due toPyruvate kinasePhospho fructokinase IPhospho fructokinase IIPyruvate dehydrogenase  <response>: Pyruvate kinase deficiency is an inherited disorder that affects red blood cells, which carry oxygen to the body;s tissues. People with this disorder have a condition known as chronic hemolytic anemia, in which red blood cells are broken down undergo hemolysis prematurely, resulting in a shoage of red blood cells 