<prompt> First clinical sign of Vitamin-A deficiency isNight blindnessConjunctival xerosisBitots spotsKeratomalacia  <response>: All the ocular manifestations of Vitamin-A deficiency are collectively known as Xerophthalmia Dry Eye Xerophthalmia is most common in children aged 1 - 3 yearsFirst clinical sign of Vitamin-A deficiency: Conjunctival xerosisFirst clinical symptom of Vitamin-A deficiency: Night blindnessConjunctival xerosis in Xerophthalmia has a characteristic appearance of emerging like sand banks at receding tideBitots Spots are triangular, pearly-white or yellowish, foamy spots on bulbar conjunctiva, on either side of cornea; In young children they indicate Vitamin-A deficiency, whereas in adults they are often inactive sequelae of earlier disease 