<prompt> Spherocytosis in blood smear seen in-a Haemoglobin-Cb Mechanical traumac Hereditary spherocytosis d Hereditary elliptosisabcacdacbcd  <response>: Spherocytes Spherocytes are small, spherical red blood cells RBC.Spherocytes are approximately two-third the diameter of normal RBC.In comparison to normal erythrocytes, they have a decreased surface area to volume ratio.They are more densely hemoglobinized and lack a zone of central pallor normal erythrocytes have central 13rd pallorCauses of spherocytes Immunohemolytic anemia Most common cause.Defect in red cell membrane.Hereditary elliptocytosisBumsG-6-PD deficiencyWilsons diseaseHereditary spherocytosisHypophosphatemiaToxins Zinc toxicosis, Coral snake venom.Trauma to erythrocytes, e.g., in microangiopathic hemolytic anemia like DIC.Paroxysmal cold hemoglobinuria.4-hydroxyphenolpyruvate hydroxylase deficiency.Rhesus deficiency syndrome. 