<prompt> Multinucleate giant cells are seen in Tzanck smear inVZVBullous pemphigoidToxic epidermal necrolysisPemphigus  <response>: In viral infections, Tzanck test shows multinucleated giant cells Tzanck cells in center. Tzanck smear, is scraping of an ulcer base to look for Tzanck cells. It is sometimes also called the chickenpox skin test and the herpes skin test, varicella zoster virus skin test. Ref Harrison 20th edition pg 1256 