<prompt> The patient whose hands are developmentally delayed with a short, stocky build. Which of the following is the most likely diagnosis?achondroplastic dwarfDown syndromeKlinefelters syndromepseudohypoparathyroidism  <response>: d Source: Felig, pp. 1143-1145The deformity of the hands is due to short metacarpals. Other deformities include short metatarsals, round facies, and thickening of the calvarium. The syndrome is caused by target organ unresponsiveness to PTH, and was the first hormone resistance syndrome described. 