<prompt> Lalloo, 60 years of age, a known case of cirrhosis liver, presents with increased levels of Alpha feto protein, hepatomegaly 3 cm below costal margin. USG showed lesions involving the right lobe of the liver. What is the most probable diagnosis :Focal nodular hyper-plasiaHepatocellular carinomaHepatic adenomaMetastasis  <response>: Answer is B Hepatocellular Carcinoma: Presence of elevated Alphaletoprotein levels tumor marker and hepatomegaly most common clinical sign in a sixty year old patient with cirrhosis predisposing factor suggests the diagnosis of hepatocellular carcinoma. 