<prompt> All the following are signs of necrosis ExceptLipofuscinCell Membrane RuptureKaryolysisKaryorrhexis  <response>: Lipofuscin, also known as wear and tear pigment, appears in the form of brown granules in the cytoplasm of living cells but is not a sign of necrosis. Pyknosis, karyolysis, and karyorrhexis terms that describe nuclear changes in dead or irreversibly injured cells. Cell membrane rupture is also associated with cell death, and is a sign of irreversible cell injury. 