<prompt> The most common cause of suppurative cholangitis is:-Stone in common bile ductCancer of the ampulla of vaterCholedochal cystEmpyema of gallbladder  <response>: CHOLANGITIS Ascending bacterial infection of the biliary ductal system with obstruction MC cause of acute cholangitis is choledocholithiasis MC causative organism- E. coli, Klebsiella pneumonia, Streptococcus faecalis, Bacteroid fragills. Treatment Initial treatment: IV antibiotics aggressive hydration. 