<prompt> Which of the followng parameters is not monitored in a patient on methotrexate therapy?Liver function testsLung function testEye examinationHemogram  <response>: Ans. is c i.e., Eye examination If you know the adverse effects of methotrexate, you can easily understand the investigations which are required in patients taking methotrexate. Adverse effects of methotrexate o Hematological toxicity: Myelosuppression, megaloblastic anemia and pancytopenia. So, hemogram is required. Organ toxicity: Nephrotoxicity renal function test, Liver toxicity Liver function test, Pulmonary toxicity Pulmonary function test and Neurotoxicity with intrathecal administration. Nodulosis, oral ulceration, GI upsets, and photosensitivity. 