<prompt> Histology of Alpo syndrome-Foamy cells in interstitiumFoamy cells in tubular epithelial cellsThickening of GBM 100 nmThinning of GBM 100 nm  <response>: Alpo syndrome: EM is diagnostic and shows basket weave appearance of the GBM. Alpo syndrome: Hereditary nephritis Abnormal a3 COL4A3, a4 COL4A4, or a5 COL4A5 chain of type IV collagen Hematuria with progression to chronic renal failure Nerve deafness Eye disorders Foamy cells in the interstitium. Ref: RAM DAS NAYAK EXAM PREPARATORY MANUAL FOR UNDERGRADUATES 2nd ed. pg no: 612 