<prompt> Which of the following is NOT effective in controlling the hot flushes of menopause in a woman?Hormone replacement therapyTiboloneRaloxifeneIsoflavones  <response>: Ans is c i.e., RaloxifeneHot Flushes : They are the hallmark of menopause. Hot flushes are described as recurrent transient period of flushing, sweating and a sensation of heat often accompanied by palpitations. feelings of anxiety. and sometimes followed by chills.The entire episode lasts no more than 1-3 minutes and recurs 5-10 times day can occur upto 30 times a day. Sho term estrogen therapy results in resolution of hot flushes.Hormone therapyEstrogen therapy most effectiveCombined estrogen and progestin therapyProgestin therapy to be given in those women in whom estrogen is contraindicatedTiboloneNon hormonal prescription medicines :Not FDA approvedClonidineSelective serotonin reuptake inhibitor : paroxetine, fluoxetineSerotonin and nor epinephrine reuptake inhibitor : venlafaxineDopamine antagonist : VeraliprideGabapentinBellergal combination of ergotamines, phenobarbital and belladona, approved for the treatment of migrain.MeazapineTrazodoneNon prescription medicines :Isoflavones 100 mgdaySoy products 60 gdVitamin E 800 IUdayLife style changes :Reducing body temperatureMaintaining a healthy weightSmoking cessationPaced respiration 