<prompt> Serum amyloid associated protein is increased in?Alzheimers diseaseAnkylosing spondylitisChronic renal failureMalignant hypertension  <response>: Secondary Amyloidosis Reactive Systemic Amyloidosis is associated with amyloid deposits that are composed of Amyloid Associated Protein A Protein.It is seen ina Chronic inflammatory conditions like RA most common, TB leprosy, osteomyelitis, ankylosing spondylitis, IBD Crohns disease, UC, bronchiectasis.b Some tumors like Renal cell carcinoma hypernephroma, Hodgkins lymphoma.SAA is produced in the liver as an acute phase reactant in the inflammatory process.The SAA is released into the circulation as an amyloid precursor and is transformed to A amyloid in lysosomes of macrophages and other cells of the reticuloendothelial system. 