<prompt> All of the following statements are TRUE about bactericidal killing, EXCEPT:Chediak-Higashi syndrome involves defect in phagolysosome formationBrutons agammaglobulinemia has normal opsonizationMyeloperoxidase acts by releasing OCl- ionsNADPH action in by release of superoxide anions  <response>: Brutons agammaglobulinemia, X-linked agammaglobulinemia XLA:Patients with XLA are pan-hypogammaglobulinemic, with decreased levels of IgG, IgM, and IgA.They exhibit poor to absent responses to antigen challenge even though viually all demonstrate normal functional T-lymphocyte responses to in vitro as well as in vivo tests eg, delayed hypersensitivity skin reactions. TThe basic defect in this disorder appears to be arrested cellular maturation at the pre-B-lymphocyte stage.Because encapsulated bacteria require antibody binding for efficient opsonization, these humoral immune-deficient patients suffer from sinusitis, pneumonia, pharyngitis, bronchitis, and otitis media secondary to infection with S pneumoniae, other streptococci, and H influenzae. Ref: Kishiyama J.L. 2010. Chapter 3. Disorders of the Immune System. In S.J. McPhee, G.D. Hammer Eds, Pathophysiology of Disease, 6e. 