<prompt> which requires thiamine pyrophosphate as the cofactor in HMP pathway?Phosphogluconate dehydrogenaseGlucose 6 PO4 dehydrogenaseTransaldolaseTransketolase  <response>: Transketolase catalyzes the transfer of a two-carbon unit from xylulose5-phosphate to ribose-5-phosphate, producing the seven-carbon ketose sedoheptulose-7-phosphate and the aldose glyceraldehyde-3-phosphate. ThusThis reaction requires two coenzymes:a Mg2 bThiamine diphosphate vitamin B1 Measurement of erythrocyte transketolase and its activation by thiamine pyrophosphate provides an index of vitamin B1 nutritional status. Reference: Harpers Illustrated Biochemistry 31stedition Page nos 183-185 