<prompt> All are typical electron microscopic features of Alpo syndrome, EXCEPT:Irregular thickening of GBMMulti Lamellation of the lamina densaBasket weave pattern of lamina densaThickening of the renal tubules  <response>: Typical electron microscopic changes in Alpo syndrome: 1. Irregular thickening of the GBM of up to 4 or 5 times the normal thickness, 2. Multi Lamellation of the lamina densa forming a basket weave pattern by inclusion of electron lucent areas, often containing round, dense granules, measuring 20-60 nm in diameter. The earliest manifestation of the GBM is irregular thinning, and the extent and severity of thickening and multi lamellation increases with age. These changes are often widespread especially in adults. Ref: Dan Med Bull 2009; 56:105-52. 