<prompt> Granulomatous diseases is are ALichen planusBHistoplasmosisCSarcoidosisDLupus erythromatosisEAsbestosisADBCDABC  <response>: Asbestosis Q, SLE cause alveolis, intersal inflammaon fibrosis, not granulomatous lesion HI 71643, H161555 SLE pulmonary manifestation H172078The most common pulmonary- manifestation of SLE is pleuritisR with or without pleural effusion.Life threatening pulmonary manifestation include interstitial inflammation leading to fibrosis,shrinking lung syndrome 1 intraalveoiar hemoorrhage.It is characterized by an accumulation of T lymphocyte, macrophage epithelioid cells organized into discrete structures granuloma in lung parenchyma.These lesions can progress to fibrosis Many paents with granulomatous lung disease remain free of severe impairment of lung funcon,or, when symptomac they improve aer treatment. Lung Response : Granulomatous H19th1708,17thi643 Known Cause Hypersensivitypneumonis Q organic dust Inorganic dusts : beryllium Q , silica Unknown cause Sarcoidosis 3 Langerhans cell granulomatosis Wegeners granulomatosis3 Allergic granulomatosis of Churgstrauss disease Bronchocentric granulomatosis Lymphomatoid granulomatosis 3 Granulomatous vasculides Granuloma of Lung:Causes Dahnert 5th489 1. Sarcoidosis Q 2. Non Sarcoid granulomatous disease Infecons Bacterial: TB, gumma Opportunisc:Crytococcosis Parasic : Dirofilaria immis dog heartworm Fungal: Histoplasmosis, Coccidioidomycosis 3 , nocardiosis Nonifecons Foreign body :Talc, beryllium 13 , algae, pollen, cellulose, lipids, abuse of nasally inhaled drugs, aspiraon of medicaon Angiocentric lymphoproliferave disease VasculidesExtrinsic allergic alveolis Langerhans cell hisocytosis Pulmonary hyalinizing granuloma 