<prompt> A five-year-old boy presents with precocious puberty and blood pressure of 13080 mmHg Estimation of which of the following will help in diagnosis17 hydroxy-progesteroneCortisolAldosterone11 deoxycortisol  <response>: At the age of 5-6 years, BP in excess of 11575 mm Hg is considered as hypertension This boy has BP 13080.So, the boy in this question has : -Precocious pubertyHypertensionPrecocious puberty in male, with salt retention and hypertension, occurs due to deficiency of 11-β Hydroxylase which catalyzes the conversion of 11 deoxycortisol to cortisol. 