<prompt> A 30-year-old pregnant woman comes to your clinic with decreased sleep, increased appetite and hyperactivity for last 2 weeks. A diagnosis of mania is made. Fuher probing reveals four episodes of major depression in the past two years. What drug will you prescribe to this patient?HaloperidolLithiumPromethazineClonazepam  <response>: Bipolar disorder - Bipolar disorder is characterized by marked mood swings between mania mood elevation and bipolar depression that cause significant personal distress or social dysfunction Bipolar I - mania depression Bipolar II - depression hypomania Mania: Decrease need for sleep Over talkativeness Abnormally increase activity levels Distractibility Increase self-esteem or grandiosity Flight of ideas Excessive involvement in pleasurable activities that have a high potential for painful consequences Duration - 7 days Hypomania - Less severe symptoms than mania Duration - 4 days Treatment:- Acute mania - mood stabilizer antipsychotic only antipsychotic In pregnancy antipsychotic is preferred because most of mood stabilizer are teratogenic Mood stabilizer - lithium DOC for acute mania, causes ebsteins anomaly, valproate most teratogenic, carbamazepine 