<prompt> Periosteal reaction in a case of acute osteomyelitis can be seen earliest at: March 20125 days10 days15 days20 days  <response>: Ans: B i.e. 10 days The earliest sign to appear on the X-ray is a periosteal new bone deposition periosteal reaction at the metaphysis. It takes about 7-10 days to appear Osteomyelitis Earliest site of involvement: Metaphysis Diagnosis of acute OM: Blood culture positive in 65 cases Periosteal reaction seen in acute OM appears after: 10 days MC organism in acute OM: Staph. aureus Brodies abscess: - Equilibrium between host organism; - Abscess cavity remains without fuher enlargement 