<prompt> What is the clearance of a substance when its concentration in the plasma is 10mgdl, its concentration in the urine is 100mgdl and urine flow is 2mlmin?0.2mlmin2mlmin20mlmin200mlmin  <response>: The Clearance of a Substance ;X; is equal to the concentration of substance X in urine UX times the urine flow per unit of time V divided by the aerial plasma level of X PX, or UXVPX.This value is called the clearance of X CX.Coming to the above question: 100 mgdl X 2 mlmin 10 mgdl 20 mlmin. 