<prompt> A 60-year-old otherwise healthy woman Presents to her physician with a 3-week history of severe headaches. A contrast CT scan reveals a small, circular, hypodense lesion with ring like contrast enhancement. Which of the following is the most likely diagnosis?High-grade astrocytomaMetastatic lesionParenchymal HaemorrhageBrain abscess  <response>: Although these CT findings can be consistent with all the options given but in immunocompetent individual there is more incidence of it being a metastatic lesion. MC cancers to metastasise to brain includes :- Lung CA, Breast CA, Melanomas, RCC, few GI tumours. These lesions become symptomatic due to mass effect from white matter edema. Rx- includes combination of Sx, radios, and whole brain radiation therapy. Immunocompromised patients are at increased risk for toxoplasmosis and central nervous system lymphomas. 