<prompt> Use of tiotropium is contraindicated in -Bronchial asthmaHypeensionUrinary retentionPeptic ulcer disease  <response>: Ans. is c i.e., Urinary retention o Tiotropium is an antimuscarinic drug and it should be avoided in patients with history of prostatic hyperplasia urinary retention -- by antagonising the action of Ach in bladder it relaxes detrusor and stimulate trigone urinary retention. 