<prompt> Characteristic radiological feature of fibrous dysplasia-Thickened bone matrixCoical erosionGround glass appearanceBone enlargement  <response>: Fibrous Dysplasia FD Asymptomatic, self-limiting developmental regional alteration of bone in which the normal architecture is replaced by fibrous tissue and nonfunctional trabeculae-like osseous tissue. It is self-limiting thus it is not a true neoplasm Represents a group of disorders with variety of clinical patterns Mutation in GNAS 1 gene Clinical forms of fibrous dysplasia of the jaws Monostotic: localized to a single bone Juvenile and aggressive juvenile Adult Polystotic: involves several bones Craniofacial McCune-Albright syndrome Jaffe syndrome ref maheswari 9th ed 