<prompt> The rationale for sucralfate therapy in peptic ulcers does not include :It has an acid neutralizing action.It inhibits pepsin mediated protein hydrolysis.It stimulates the production of epidermal growth factor.It stimulates prostaglandin synthesis.  <response>: A Sucralfate binds to the base of the ulcer crater and inhibits the pepsin mediated protein hydrolysis. It by itself has no acid neutra-lizing action. Other mechanisms proposed for its effect are stimulation of prostaglandin synthesis and stimulation of local epider-mal growth factor. 