<prompt> Which of the following is true regarding Horner;s syndrome? E. REPEAT 2008Constriction of pupilComplete ptosisExcessive sweatingLoss of accommodation  <response>: Ref: Basaks Essentials of Ophthalmology, 5th edition Explanation: HORNERS SYNDROME Clinical Features Miosis. Partial ptosis. Enophthalmos. Loss of ciliospinal reflex Unilateral absence of sweating. Congenital Horners syndrome is associated with Heterochromia Iris. Path: Damage to sympathetic innervation of the eye. Etiology In the cervical region o Apical bronchial carcinoma o Ca of neck glands. Centrally o Multiple sclerosis o Pontine tumor o Syringomyelia. Pupillary light reflex and accommodation are normal. Dilation is affected. How to differentiate Pre and Postganglionic sympathetic lesions? If the lesion lies peripherally Post-ganglionic, it dilates rapidly with 1 in 1000 adrenaline drops. This is due to Denervation super-sensitivity. Ptosis can be corrected for the cosmetic purpose by Mullerectomy. 