<prompt> Harlequins Skin change in the newborn is seen in -Autonomic dysfunctionIcthyosisSepticemiaPolycythemia  <response>: Ans. is a i.e., Autonomic dysfunction Harlequin color change o This rare but dramatic vascular event occurs in immediate newborn period and is most common in low bih weight infants. o If reflects an imbalance in the autonomic vascular regulatory mechanism. o When the infant is placed on the side, the body is bisected longitudinally into pale upper half and a deep red dependent half. Note - The fetus in ichthyosis option b appears grostesque and the appearance is called harlequin fetus. 