<prompt> Most Common extranodal site of Lymphoma in HIV is?CNSGITRetroperitoneumMediastinum  <response>: Ans. a CNSRef: Harrison 18thpg Chapter 189Lymphoma in HIV90 of lymphomas in HIV are B cell in phenotype; more than half contain EBV DNA.Immunoblastic lymphomas account for 60 of the cases of lymphoma in patients with AIDS.Primary CNS lymphoma accounts for 20 of the cases of lymphoma in patients with HIV infection.Most common extranodal site involved in Lymphoma in HIV is the CNS, which is involved in one-third of all patients with lymphoma. 