<prompt> Serine of Chymotrypsin is changed with Proline. Which of the following will happen ?Chymotrypsin can catalyze the protein but cannot bind itChymotrypsin can bind the protein but cannot catalyze itChymotrypsin can bind as well as can catalyze the proteinChymotrypsin can neither bind nor can catalyze the protein  <response>: Serine Catalytic amino acid in Chymotrypsin Whenever catalytic amino acid is changed, then the enzymatic activity decreases or getsabolished. Histidine and Aspaate residues in the active site of chymotrypsin have the function of binding to peptideprotein substrate. They are not changed so the enzyme is able to bind but not catalyze. Extra Edge: Examples of Serine proteases Chymotrypsin Trypsin Elastase Thrombin Plasmin Complement proteins Clotting factors X, XI PSA, Prostate-specific Antigen It is found that Serine proteases have a role in tumor cell metastasis. It is called site specificdirected mutagenesis oligonucleotide with single base change- UCA serine changes to CCA proline 