<prompt> A 4 year baby is having large face, large jaw, large ear and macro orchidism isMc Cuneal bright syndromeDowns syndromeCri-du chat syndromeFragile X syndrome  <response>: A child with large face large ears large jaw and macro orchidism has fragile X syndrome It is due to a fragile site in one of the distal long arm of chromosome Xq27.3 Reference: Nelson TB of pediatrics pg 411 edition 19. 