<prompt> Pyrantel pamoate is effective in both -Amoebiasis and trichuriasisEnterobius and ascariasisAmoebiasis and strogyloidesTaenia solium and ascariasis  <response>: Ans. is b i.e., Enterobius and ascariasis Pyrantel tmoate o Pyrantel pamoate is effective against ascaris, enterobius, ancylostoma, strongyloides and necator. o It causes activation of nicotine cholinergic receptors at NM junction in the worms -- persistant depolarization -- spastic paralysis. o It is not safe in pregnant women and children less than 2 years. 