<prompt> All the following about drug induced SLE are true exceptMore common in femalesRenal and CNS involvement is uncommonComplement level are normalThe disease remits after withdrawal of the offending drug  <response>: Ans. a More common in femalesRef: Robbins 9thpg 218; 8thpg 213Drug-Induced LupusIt is a syndrome of positive ANA associated with symptoms such as fever, malaise, arthritis or intense arthralgiasmyalgias, serositis, andor rash.It appears during therapy with certain medications like antiarrhythmics procainamide, disopyramide, and propafenone; antihypertensive hydralazine; antithyroid propylthiouracil; antipsychotics chlorpromazine and lithium; anticonvulsants carbamazepine and phenytoin; antibiotics isoniazid, minocycline nitrofurantoin; antirheumatic sulfasalazine; diuretic hydrochlorothiazide;It is predominant in whites has less female predilection than SLEIt rarely involves kidneys or brain, is rarely associated with anti-dsDNA, is commonly associated with antibodies to histonesIt usually resolves over several weeks after discontinuation of the offending medication. 