<prompt> Wire loop lesion seen in lupus nephritis is due toCapillary wall thickeningBasement membrane thickeningSubepithelial depositsSclerosis of mesangium  <response>: Subendothelial immune complex deposits may create a circumferential thickening of the capillary wall, forming wire loop structures on light microscopy. This condition is seen in lupus nephritis. 50 of SLE patients have clinically significant renal involvement Currently there are six pattern of glomerular disease Where, Class 1Minimal mesangial lupus nephritis is least common and class 4Diffuse lupus nephritis is most common 