<prompt> True about immune response of hepatitis B is:Antibody of HBsAg is associated with resistance to infectionAntibody to HBc is not protectiveHighest titres of anti-HBc are found in persistent carriers of HBsAgCMI disappears soon after recover  <response>: Hepatitis B virus natural infection induces lifelong immunity.The immunity is primarily mediated by humoral antibodies against HBsAg. Antibodies to HBsAg are protective. These antibodies bind to surface antigens or with the virus and prevent it from interacting with receptors on the hepatocytes.These antibodies appear to neutralize the infectivity of HBV.Parija SC. Textbook of Microbiology Immunology. Elsevier Health Sciences; 2014. Page:552 