<prompt> Lamivudine is recommended for treatment of chronic hepatitis B when:HBe Ag positiveHBe Ag NegativeALT 2 xULNViral DNA 102 copies  <response>: Answer is C ALT 2x ULN The primary indication of antiviral treatment in chronic hepatitis B is elevation of ALT levels to more than 2 times the upper limit of normal. Antiviral treatment is recommended for treatment of chronic hepatic B in both HBe Ag positive and HBe Ag negative individuals when HBV DNA 2 x 104 Um1 and ALT 2 times ULN. Lamivudine is the first of the nucleoside analogues to be approved and may be used for Antiviral treatment in such cases although newer, more potent agents are now generally preferred. 