<prompt> First manifestation of Alport syndrome is :Microscopic haematuriaProteinuriaOliguriaSensorineural deafness  <response>: Ans. is a Microscopic hematuria Ref Harrison, 17e p 2469, 16e, p 2331 15e, p 1595.The first symptom of Alports syndrome is not mentioned anywhere.But in Harrison it is written that patients with Alports syndrome usually presents with microscopic hematuria, proteinuria nephrotic range in 30 and progressive renal insufficiency.So the first symptom of Alports syndrome can be taken as microscopic hematuria.Common extra renal manifestations include:Sensorineural hearing loss 60.Bilateral anterior lenticonus SC 15-30Recurrent corneal erosions. 