<prompt> Tau proteins are most commonly associated with -Alzheimers diseaseAlcoholismTuberculosisMeningitis  <response>: Ans. is a i.e., Alzheimers disease o In Alzheimers disease excessive or abnormal phosphorylation of tau results in the transformation of normal adult tau into PHF-tau paired helical filament and NFTs neurofibrillary tanglesImportant pathological findings in Alzheimers disease.1 Cortical atrophy with sidening of the cerebral sulci.2 Compensatory ventricular enlargement - Hydrocephalus exvacuo.3 Neuritic senile plaques - Made up of A b40 A b42.4 Diffuse plaques - Contain Ab42.5 Neurofibrillary tangles - Contain tau protein6 Cerebral amyloid angiopathy7 Granulovascular degeneration8 Hirano bodies 