<prompt> Chances of veical transmission of Hepatitis B may be high as25406090  <response>: Answer is D 90 The rate of perinatal transmission of hepatitis B HBV essentially depends on the presence or absence of HBe Ag and viral replication. The rate of perinatal transmission of HBV may be as high as 90 in neonates born to mothers who are positive for HBe AG. The likelihood of perinatal transmission of HBV correlates with the presence of HBe Ag and high level viral replication. 90 of HBe Ag positive mothers but only 10-15 of Anti-HBe Ag negative mothers transmit HBV to their offspring - Harrison 18th2547 Transmission of infection from an HBV carrier mother to her neonate accounts for the majority of new infections in the world today. Sixty to 90 of Hepatitis B surface antigen HBs Ag positive mothers who are Hepatitis B e antigen HBe Ag positive transmit the disease to their offspring, whereas mothers who are positive for antibody to HBe Ag Anti - HBe do so less frequently 15-20. - 