<prompt> Fluconazole differs from ketoconazole in the following aspectIt is not active by the oral routeIt is a more potent inhibitor of drug metabolismIt is not effective in cryptococcal meningitisIt is unlikely to produce anti-androgenic side effects  <response>: Fluconazole is a preferred agent because it hasVery good oral absorption.Maximum CNS penetration. therefore effective in cryptococcal meningitis.No inhibitory action on microsomal enzymes.No anti-androgenic property. 