<prompt> the above condition is due to execessive usage of ?ticeplaninpipericellinVANCOMYCINmetronidazole  <response>: image shows red man syndrome which is a side effect of vancomycin usage which increases histamines and causes flushing of the skin Vancomycin: Red Man Syndrome Constellation of symptoms : Pruritus, flushing, erythroderma common : Hypotension uncommon Due to nonspecific histamine release that is rate related rare repos of IgE-anaphylaxis Severity correlates with amount of histamine released into plasma Severity reduced by reducing rate to 500 mghr and premedication with H1-antagonists ref : kd tripathi 8th ed 