<prompt> Solitary bone lesion that does not arise from metaphysis isGiant cell tumourSimple bone cystAneurysmal bone cystFibrous dysplasia  <response>: Differential diagnosis of a solitary bone lesion Features Giant cell tumour Simple bone cyst Aneurysmal bone cyst Fibrous dysplasia Age 20-40 yrs 20 yrs 10-40 yrs 20-30 yrs Common bones Lower femur, Upper tibia Lower radius Upper humerus Upper femur Tibia, Humerus Neck of the femur, Tibia Location Epiphysis Metaphysis Metaphysis Metaphysis X-ray Soap-bubble appearance, Eccentrically placed Maximum width less than width of the growth plate Distending lesion, ballooning the bone Multi-loculated Ground-glass appearance Trabeculations Treatment preferred Excision Curettage and bone graft Curettage and bone graft Curettage and bone graft Reference: Maheshwari; Essential Ohopaedics; Page no: 237 