<prompt> A 50-year-old male presents with hematuria. He is diagnosed of having bladder cancer which extends muscle deep. The best treatment:Intra vesical chemotherapyNeoadjuvant chemotherapy followed by radical cystectomyRadiotherapyTransurethral resection  <response>: Ans. b Neoadjuvant chemotherapy followed by radical cystectomyRef: Bailey 26th Edition, Page 1335 Neoadjuvant chemotherapy improves survival by about 5 -7 . Radical cystectomy is the standard treatment for muscle invasive bladder cancer. 