<prompt> Predominantly osteoblastic metastasis is seen in?Renal cell carcinomaProstate carcinomaBreast carcinomaThyroid carcinoma  <response>: ANSWER: B Prostate carcinomaREF: With textRepeat from December 2009Osteoblastic metastasis is less common in breast cancer but are well documented in metastatic prostate cancer REF: Integrationinteraction of oncologic growth - Gary G. Meadows Page 157Osteoblastic metastasis occurs most commonly in prostate cancer. However other tumours that metastasize to bone or grow in bone e.g. Breast cancer, can also give rise to osteoblastic disease REF: Textbook of bone metastases - Claude Jasmin, Rodolfo Capanna Page 41Purely osteoblastic metastasis is most often associated with prostate and breast cancer, but also with Hodgkins lymphoma, carcinoids and medulloblastomas. Breast cancer metastases are most commonly mixed and less commonly purely osteolytic or osteoblastic. Prostate cancer is characteristically osteoblasticREF: Differential Diagnosis in Conventional Radiology - Francis A. Burgener, Martti Kormano, Tomi Pudas -Page 110 