<prompt> In Gaucher;s disease, there is a deficiency ofGlucocerebrosidesglucokinaseSphingomyelinaseG-6PD  <response>: Due to deficiency of glucocerebrosidase, causes glucosylceramide accumulation in macrophages called Gaucher;s cells.DiseaseEnzyme DeficiencyClinical SymptomsGaucher diseaseb-GlucosidaseEnlarged liver and spleen, erosion of long bones,mental retardation in infantsRef: Harper;s biochemistry; 30th edition; Chapter 24 Metabolism of Acylglycerols Sphingolipids 