<prompt> Bronze diabetes is seen in-Wilsons diseaseSarcoidosisLead intoxicationHemochromatosis  <response>: Ans. is d i.e., Hemochromatosis o In hemochromatosis deposition of iron in the skin causes pigmentation bronzing of the skin and deposition of iron in the pancreas produces diabetes therefore the term bronze diabetes.o The clinical features of hemochromatosis are characterized principally by deposition of excess iron in the following organs in decreasing order of severity.Liver 95o Usually the first organ to be affected,o Hepatomegaly seen in most of the cases,o Micronodular cirrhosis is characteristico Hepatocellular carcinoma develops in 30 patientsSkin 90o Excessive skin pigmentation Bronzing of the skino Skin pigmentation results partially due to hemosiderin deposition and mainly due to melanin depositiono Usually diffuse or generalized, but more pronounced on the face, neck and extensor aspects of lower forearmsPancreas 65o Leads to diabetes meilitusJoints 25-50o Arthropathyo PolyarthritisCardiaco Congestive heart failureo Arryhthmiao Cardiomyopathy RestrictiveHypogonadismo These changes are primarily the result of decreased production of gonadotropins due to impairment of hypothalamic-pituitary function by iron deposition however, primary testicular dysfunction may be seen in some cases 