<prompt> Which of the following is not true about ocular manifestation of HIV?50 of patients have cotton wool spotsKaposis sarcoma can be present on the eyelids75 show vascular narrowingCotton wool spot harbors CMV  <response>: Ophthalmologic problems occur in 50 of patients with advanced HIV infection. These are:- Funduscopy- cotton-wool spots-represent areas of retinal ischemia secondary to microvascular disease and are axoplasmic debris of dead neurons and dont harbour CMV, no visual loss-- patient stable improve with time CMV retinitis CD4 T cell count 100 mL but majority occur at CD4 T cell count 50mL - CF : blurred vision, floaters, and scintillations. - The disease is usually bilateral, although typically it affects one eye more than the other. The characteristic retinal appearance is that of perivascular hemorrhage and exudate-- visual loss is irreversible P. jirovecii can cause a lesion of the choroid that may be detected as an incidental finding on ophthalmologic examination. - These lesions are typically bilateral, are from half to twice the disc diameter in size, and appear as slightly elevated yellow-white plaques. They are usually asymptomatic and may be confused with cotton-wool spots. Chorioretinitis due to toxoplasmosis can be seen alone or, more commonly, in association with CNS toxoplasmosis. Kaposi sarcoma may involve the eyelid or conjunctiva, while lymphoma may involve the retina. Syphilis may lead to a uveitis that is highly associated with the presence of neurosyphilis. 