<prompt> All of the following are true about HMG CoA reductase inhibitor exceptCNs accumulation of simvastatin and livastatin is high less for prevastatin and fluvastatinSimvastatin is rapidly and prevastatin is leastly metabolizedBioavailability is minimally modified when prevastatin is taken with foodFibrinogen levels are increased by prevastatin  <response>: Refer Goodman and Gilman 11e p950 Prevastatin has least chances of drug interactions because it is metabolized by non microsomal enzyme. It also have minimum chances of myopathy among stations. Bioavailability of prevastatin is leastly affected with food intake. It has little CNs penetration 