<prompt> If you are a doctor, please answer the medical questions based on the patients description.how can protein in urine and water retention be cured in a post kidney transplant patient?my mother is 50 yrs old had kidney transplant 2 yrs back but now though is normal on test reports --urine routine --protein 4from last 4 months as this is little alarming so i am worried to know how to treat control it  <response>: Hi, I had gone through the reports. Urine protein is not a good sign, it might either indicate recurrence of primary kidney disease glomerulonephrtis Diabetic nephropathy or development of newer kidney problem Lenovo Glomerulonephritis Virus infection in transplanted kidney, either of which would warrant kidney biopsy. It can be managed now, depending upon kidney biopsy result. If not intervened, there is a risk of graft loss. 