<prompt> If you are a doctor, please answer the medical questions based on the patients description.hi doctor my mther is 45 years soffering from asthma n copd from last 5 years...she right now has severe wheezing and fever...we have given her injection deriphylline2ml im , i want to knw can we administer it everytime she has an acute exacerberation???  <response>: Hello, Well, it can overdose. It is generally recommended to be given no more than 4 times a day total dose of 300 mg per 24 hrs.; and 2 ml is on the large size of dosing. Funny story: my mother had an overdose of it when she 1 started taking her recommended dose 2 took erythromycin which causes it to accumulate 3 stopped cigarettes which lower its metabolism when you stop 4 had the flu which lowers the metabolism of it but 5 won a casino jackpot and hyperventilated which triggered the seizure. So, a lot of factors can influence this Chat Doctor. Hope I have answered your query. Let me know if I can assist you further. Take care 