<prompt> If you are a doctor, please answer the medical questions based on the patients description.Hi - I drank heavily on consecutive nights Friday and Saturday night and had a few drinks on Tuesday night preceding a liver panel test on Wednesday. My AST was found to be high 58 on a normal scale of 0-55 ul. ALT was normal 32 on a normal scale of 0-69 ul. Should I be concerned or were the drinking sessions of the past week to blame for the elevated AST levels? Thank you.  <response>: Hello! Thanks for putting your query in Chat Doctor. I am a Gastroenterologist DM. Increase in AST is due to liver cell injury which may be due to alcohol intake. It is a matter of concern as prolonged liver injury can cause cirrhosis that is shrinkage of liver which is irreversible. So I will advise you to avoid alcohol. Also, other common and treatable causes like Hepatitis B and C virus, Serum ceruloplasmin for Wilson disease especially if you are young, ANA and SMA for autoimmune disease are to be investigated as they also cause increase in ANTI hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon. 