<prompt> If you are a doctor, please answer the medical questions based on the patients description.I took ibuprofen for two weeks.. into that two week time I noticed a minimal amount of hives. I I was then put on an antihistamine and they subsided somewhat and then came back full force. C would the ibuprofen still be in my system? orce.  <response>: Hello. Thank you for asking at Chat Doctor. I went through your history and would like to make suggestions for you as follows:1. Allergic reactionhives to Ibuprofen are fairly common. It doesnt mean that ibuprofen is still in system, but the chemicals increased by it causing allergic reactions like histamines, leukotrienes and other may be still increased in skinblood.2. Were I treating you, I would suggest you a combination of montelukast and levocetirizine for 5-7 days.3. I would also suggest you to apply a lotion like calamine over itchy areas and hives. Hope above suggestions will be helpful to you. Should you have any further query, please feel free to ask at Chat Doctor. Wish you the best of the health. Thank you Regards. 