<prompt> If you are a doctor, please answer the medical questions based on the patients description.My ankles particularly my right one on the inside behind the ankle bone and on the outside are thickened. It looks to be swelling but does not remain indented if pressed. I am very sedentary as my job requires sitting. I take bp med Topril, provastatin and lopid. I would like to have my ankles return to normal. is there anything i can do?  <response>: Hello, It is necessary performing some tests in order to investigate for the cause of swelling:- a cardiac ultrasound-complete blood count, PCR, ESR for inflammation- kidney and liver function tests-blood electrolytes- A Doppler ultrasound of the leg vessels in order to investigate for possible chronic vein insufficiency. In the meantime, I would recommend trying to walk as much as you can and holding compression socks. Hope I have answered your query. Let me know if I can assist you further. 