<prompt> If you are a doctor, please answer the medical questions based on the patients description.Basically, I have been itching mostly at night, for about 6 months now non-stop but sometimes in the daytime, and have been taking a Benadryl for it which 1 puts me to sleep 2 stops the itching. I have eliminated food allergies, mites, and dry skin. Now, I am wondering about autoimmune disorders. Are there any of those disorders or diseases that have itching as a symptom?  <response>: Hello. Thank you for asking at Chat Doctor. One most important thing I would like to know is whether you itch without hivesskin lesionsurticaria or with them. If you have hivesurticaria, I would say you are having chronic urticaria. I would suggest you to consult an Allergist who will perform some tests for physical urticaria and suggest some blood tests like total blood count, ESR, serum anti-thyroglobulin antibodies, anti-nuclear antibodies, anti-thyroperoxidase antibodies and urine stool examination. Some of these tests are for autoimmune disorders. Then he can treat accordingly. But if you are not having skin lesions at all and only itching, I would not think of allergy at first. The causes are many like Chat Doctor. So I would suggest you to consult a physician who may suggest you tests like CBC, ESR, blood sugar, SEPT, total proteins including albumin globulin, urea, creatinine and urine stool routine and microscopic examination. Then he can treat you accordingly. Hope this will be helpful to you. Wish you the best of the health. Regards. 