<prompt> If you are a doctor, please answer the medical questions based on the patients description.Ive been on Zoloft 200 and wellbutrin 150xl I was on sr 100 its been over 6 weeks and not much difference other than feeling anxious. Ive been on anti-depressants for a good part of my life. I am 59. psychiatrists just want to increase all the time, but I am sensitive to med;s, I feel worse. I wish a doctor could really help me out. suggestions would be greatly appreciated. why is it so hard to find a doctor to help--Ive been praying over 20 years. there was a dr. wm. annatto who helped me out and moved. I heard he is at UMDNJ and cannot locate him. could you help me.  <response>: I would like to know what disease you have been having, what are the symptoms of mental illness. The Chat Doctor. Bupropion Wellbutrin is not effective for anxiety. You must consult a psychiatrist to know what is your diagnosis, and he will give you medications accordingly. If these two medications are not effective, there are many other options including complementary alternative medications, lifestyle changes, yoga and meditation. We need to know more about your illness to help you further. 