<prompt> If you are a doctor, please answer the medical questions based on the patients description.Hi! am Getruda George, There is a kid of 3yrs came with jaundice , fever and diff. on breathing for 3days on examination, there is nasal polyps, hepatomegally about 5cm below right coastal margin. LFT results aspartate aminintransferase, total bilirubin are high, full blood picture shows leukocytosis, rised platelets and WBCs. malaria and hepatitis b tested negative. what could be the problem  <response>: Obviously you should consider Hepatitis A, as well as Epstein Barr Virus and Cytomegalovirus which can both give an upper respiratory tract picture with enlarged lymph nodes, liver or spleen. Cholangitis Virchow triad of fever pain and jaundice is also in the differential diagnosis as is a myogenic live abscess, although that is pretty rare. I would certainly focus on supportive care HY Chat Doctor. This child sounds sick and should be cared for in a hospital if possible. 