<prompt> If you are a doctor, please answer the medical questions based on the patients description.Hi dr.,my wife had undergone follicle study and the egg was ruptured on 12th day so my gyn told to have sex from that day itself.We had sex once in a day from 12th day to 20th day . On today she got her periods. i have a question Why she havent had pregnancy as we had sex during rupture of egg.Is any thing serious or she will be never pregnent.Is any problem with her.please help me I am nervous,please reply.  <response>: Dear user, welcome to Chat Doctor. It is very early to say such things. The chances of getting pregnant if you have sex at time of ovulation are no more than ten percent. So, not getting pregnant does not indicate anything serious and does not mean she will never get pregnant. One of the most important determining factors is the age of your wife. If she is under 35 years her chances are great. Then you should check your semen analysis and if normal, I suggest the following steps:- 3-6 months of timed intercourse days 11,13,15 of your wives cycle day 1 is the first day of menstrual flow.- 3 cycles of timed intercourse according to folliculometry after ovulation induction by camphene of BMG injections under your doctors supervision.- 3 cycles of ovulation induction followed by intrauterine insemination.- if no pregnancy occurs go for invited fertilization or intro cytoplasmic sperm injection. I wish you good luck and your wife getting pregnant soon. 