<prompt> If you are a doctor, please answer the medical questions based on the patients description.I have been taking diovan and inderal for HBP. Occassionaly my readings spike into the danger zone. 188110. This weekend it spiked to 220120 but I had no symptoms, felt good. For the past six months I have been walking 2 12 miles every day, eat healthy, am not overweight, I am a 55 year old female. I have been tested for adrenal insufficency and that is okay. I do have a couple of drinks every day and am wondering if this is causing the sometime spikes. Any other possible reason why you might think this is happpening?  <response>: Hello, I passed carefully through your question and would explain that these spikes could be related to different possible causes: anxiety, physical activity, thyroid gland dysfunction, caffeine intake, etc. For this reason, I would recommend avoiding caffeine intake and checking thyroid hormone levels. Regular physical activity and a maximal reduction in salt intake would help avoid these spikes in blood pressure values. Hope I have answered your query. Let me know if I can assist you further. Take care Chat Doctor. 