<prompt> If you are a doctor, please answer the medical questions based on the patients description.I woke up yesterday with a swollen lip, bottom lip left side with what seem to be hives, as far as i know i have no allergies, my lip itches and burns and after 36 hours is still swollen, what could be the cause and how do you think i could fix it?  <response>: Hello and welcome to Chat Doctor I would keep a possibility of Angioedema. Angioedema or Quinces edema is the rapid swelling of the dermis, subcutaneous tissue, mucosa and submucosal tissues. It can be either Acquired OR Hereditary Angioedema. I would have liked to gather some more information from you regarding your concern in order to be able to help you better.-Since how long do you have this problem? -Are you on some oral medications? Painkillers? Antihypertensives? -Do you also suffer from HivesUrticaria? -Does anybody else in your family has the same problem? Apart from being hereditary, Angioedema can occur due to various other causes likesimilar to urticaria:--Infectionsbacterial, viral, fungal -- Chat Doctor. I would advise you to get few basic lab tests like Hologram, stool for ovacyst, Urine routine, Chest X-Ray. An oral antihistamine like Fexofenadine Allegra 180 mg tab OR Loratadine Alaskan 10 mg tablet once or twice daily for a week would be suitable. They are non-sedating and wont affect your alertness level. If I was your treating doctor I would have also given you a shot of injectable antihistamines like Evilpheniramine and Injectable effcorlinHY 