<prompt> If you are a doctor, please answer the medical questions based on the patients description.My husbands MRI came back stating there is a focal region of cystic encephalomalacia and gliosis in the left cerebral hemisphere primarily within the portion of the head and body of the left caudate nucleus. I have been trying to find a explanation online with no luck. Please explain what that means and symptoms.  <response>: Hello Cystic encephalomalaciagloss refers to loss of normal brain tissue, and it is filled by glial cells. It may be due to many reasons like post trauma, infection,ischemiastroke etc. Gliosis is a reparative mechanism in brain tissue. There is small area of gloss in your husbands case. This condition doesnt need any specific treatment. It is a healed stage and patient only need symptomatic treatment. Get well soon. Take Care Chat Doctor. 