<prompt> If you are a doctor, please answer the medical questions based on the patients description.hi,my sister has chronic lower left abdominal pain and recently had chest problems to which she was prescribed antibiotics and omeprazole for the stomach. now she s having swollen ankles and some blistersulcers on both lower legs. is this an indication of some underlying problem?  <response>: Hi I did review your concern. These symptoms of various different regions raise the suspicion of vasculitisautoimmune disease. I would recommend you to consult an immunologistrheumatologistphysician for further testing and evaluation like CBC, ANA,ANNA and also biopsy of local leg lesions if required. Early diagnosis and treatment is warranted. I hope this suggestion yellowish you both the best of health and success. 