<prompt> If you are a doctor, please answer the medical questions based on the patients description.I was vaccinated against hepatitis B more than 18 years ago and received a booster shot 10 years ago test indicated that Hepatitis Bs anitbidy was reactive 50.3 mIUml before the booster shot. I noticed that my Hepatitis Bs antibody has increased annually it was 270.2 mIUml in 2010. My wife is a HBV carrier. Does the increase indicate that my wife Hepatitis B virus is turning active?  <response>: Changes in your blood tests do not indicate anything specific about your wives hepatitis B status. She needs to have her own blood tests to see what is happening to her disease. There are treatments for hepatitis B now, so I suggest she get followed up in any case. Your rising levels could be related to the booster shot. I know you are thinking perhaps they are rising in response to contact with her virus. Certainly this is a possibility, but again, its best that she get checked periodically anyway and consider treatment for her carrier state. Hope this helps. 