<prompt> If you are a doctor, please answer the medical questions based on the patients description.I am a 52yo female, non smoker. I am on .25mg estroge patch and 100 mg progesterone daily. I am experiencing a sharp pain under the left ribs. It occurs between 4 and 5 am and stays with me until about noon every day. Aim currently ring treated for acid reflux. Activity seems to give some relief.  <response>: Respected madam, hi I evaluated your query thoroughly.Certain vital information missing here - was there pain before estrogen progesterone therapy starting ?- sleep pattern-need medications for sharp pain if any ?- any other symptoms associated like breathlessness perspiration palpitations along with it ?Till you revert with details I can say this pain to be Costco Chat Doctor. Thanks for using Chat Doctor reviewing my answer. Regards dear take care. 