<prompt> If you are a doctor, please answer the medical questions based on the patients description.Hello I am worrying franticall about unusual twitching in my legs and occasionally my arms too. I notice it more at night when I m trying to go to sleep, but have also started to notice it through the day a little as well. Is this because it s on my mind a lot and perhaps the more I think about it, the worse it will seem? I thought it could be RLS, but am terrified it could be something more sinister like MS or Parkinson s Disease...  <response>: Hello, It is necessary consulting with your attending physician for a physical exam and performing some tests in order to investigate on the possible cause underlying your complaints:- Complete blood count or anemia-Vitamin D and vitamin B12 plasma levels for possible deficiency-Blood electrolytes- Nerve conduction studies in order to exclude possible should discuss with your doctor on the above tests. I would exclude MS and Parkinsons disease, because they do not cause muscle twitching. Hope I have answered your question. Let me know if I can assist you further. 