<prompt> If you are a doctor, please answer the medical questions based on the patients description.Recently while driving through the mountains in Pennsylvania I felt a strong tightness in my chest. I was on HRT in the fall, but was taken off because of loss of eye sight in one eye...also had this tightening in my chest. Since then I have been fine...up until now. What do you think?  <response>: Respected user, hi I evaluated your query thoroughly. Relates to decreased lung oxygenation at heights in mountains causing sudden tightening of the chest, a normal physiological phenomenon observed in the majority of people without any underlying pathology. Hope this helps you. Welcome for any further assistance. Thanks for using Chat Doctor .com giving me an opportunity to assist you. Wishing you a very happy healthy life ahead. Regards dear take care. 