<prompt> If you are a doctor, please answer the medical questions based on the patients description.Good day, I am a 50 years old male that always tried to keep in pretty good shape playing sports. I would say that my drinking habit are in the norm, to not drink hard liquor and rarely beers but love a few glasses of red wine 4 glassesweek during that week. I always did have problem with my cholesterol problem treglycerides level and LDL level. In the last 20 years have been carrying an extra 20 pounds for sure. recently I had a Ultra-sound with the following finding: Diffuse fatty infiltration of the liver. Coarsening of the hepatic echotexture could relate to underlying hepatocellular disease. I am very nervous especially with the last portion: Hepatocellular disease. Could you please provide your thought on this one? thank you.  <response>: Hello, thanks for writing in. Hepatocellular disease is a broad term for any condition that leads to impaired cell function and death. It is a diffuse parenchymal involvement- this can include fatty liver, inflammation, infection, metabolic disorders, malignancy etc. In your report the diffuse fat deposition is likely the hepatocellular disease. However, I would suggest you talk to your doctor and check your liver enzymes. If there is any doubt of a malignant process, a liver tumor marker test, followed by a CT with SOS biopsy can be done. But a diffuse malignancy seems less likely, so do not worry. Hope I have helped you answer your query. Take care. 