<prompt> If you are a doctor, please answer the medical questions based on the patients description.Doctor, I have noticed knee swelling, lymphedema and my skin on arm and hand, also leg and foot looks infected. What might be the problem?  <response>: Based on your symptoms, it is possible that you are suffering from Osteomyelitis. It is a bone infection caused by bacteria that enters through the skin and spreads into the bone. 