<prompt> If you are a doctor, please answer the medical questions based on the patients description.Hi Doctor ,My wife is suffering for the Joint pain for long time , all the test we did like anti ccp , uric acid, CRP,TLC,DLC, ESR ,blood sugar are within the normal limits. However her pain increases with the swelling in the left leg whenever she walls even for short distance few steps only. Please advice  <response>: Hi, Thanks for your query. Repeated joint pains can be due to multiple causes at this age the commonest being poly arthralgia. Other causes can be rheumatoid arthritis, gout, inflammatory diseases like SHE, bursitis, fibromyalgia, etc. For proper diagnosis, some blood tests are advisable like- 1. Serum calcium levels.2. Serum Uric acid levels.3. RA factor4. ESR and CRP5. Serum Creatinine6. X-ray of affected joints. You need a thorough clinical examination followed by investigations under the guidance of an orthopedic. Till then for symptomatic relief, you can take over the counter analgesics, do hot fomentation and apply local analgesic gel on the affected areas. I do hope that you have found something helpful, and I will be glad to answer any further query. Take care 