<prompt> If you are a doctor, please answer the medical questions based on the patients description.Hello doctor i m suffering from irregular periods for about 4 to 5 years now i m takint meprate for now but i m reallly puting on weight for the past years could u help me with an alternative? Or should i continue with meprate for my PCOS problem Kindly help me Thank u Arti  <response>: Hello, Meprate tablets contain a chemical similar to the female hormone progesterone. It may cause weight gain as a potential adverse effect on some patients. An alternative would be combined oral contraception with low dose or very low dose of estrogenprogesterone. These would be for instance Yam, Marlette, Lo String Fe, Yasmin, etc. I hope this answers your query. I remain at your disposal in case further medical assistance is needed. 