<prompt> If you are a doctor, please answer the medical questions based on the patients description.I also take MS Contin 60 mg BID. How is this holding up with the Oxycodone 10325, 4 times a day, as well as 6 tablespoons of paregoric per day. My back and knees still give me a fit, have had 3 spinal surgeries,both knees operated on, 4 heart attacks, triple by pass heart surgery, a stroke, heart failure, currently have my 2nd ICD which I have been shocked 2 times from saved me both times. Thanks for listening Paul  <response>: You should be asking your personal physician who prescribed these medications as to what combination is necessary andor adequate for the pain. If you are self treating I would highly recommend you seek out a physician to help with managing your pain. You are talking about combining a lot of high-powered opiate Chat Doctor. Please rate this a 5-STAR ENCOUNTER and feel free to write more questions to me at: XXX 