<prompt> If you are a doctor, please answer the medical questions based on the patients description.I am asthmatic since early childhood ,Now since one year I have devoloped chronic urticaria and I have raised IGE Levels normal value is 190 and mine are 350 .What kind of treatment I should have.Im taking Zantac 1BD Fexet 180mg 1 OD Softin 1 HS Zatofen 1BD is this is a right treatment?  <response>: Hi, Already you use Fexofenadine 180 mg histamine 1 blocker why you again take soften Loratadine also histamine 1 blocker. Tab Sanitizing Santa is a histamine 2 receptor blockers. Both fexofenadine and Sanitizing have synergistic effects on urticaria. Respond to treatment may take 4 to 6 weeks. Hope I have answered your query. Let me know if I can assist you further. Take care Chat Doctor. 