<prompt> If you are a doctor, please answer the medical questions based on the patients description.Dear Dr.Venkatachalam: My wife is taken Diclomax 50 Diclofenac Sodium BP 5mg for years for killing the pain of ankylosing spondylitis and Hip Joint bone problem. Now she is getting Sediment in her kidney. what is the reasons and other pain killer she can take.  <response>: Hilong term painkillers NSAIDs can cause chronic kidney diseases with alteration in the urea, creatinine, electrolyte levels which are really dangerous please stop diclofenac can start her on tab tramadol which has very mild opioid effect but very safe on the kidneys.pregabalin gabapentin in lower doses are also very good at controlling the pain of ankylosing spondylitis safe on the kidney stake care 