<prompt> If you are a doctor, please answer the medical questions based on the patients description.Hi Doctor, my question is this , my wife s blood test showed a high level of buncreatinine and aigh level of potassium .what is the cause of this , and should I be concerned? a previos blood test taken in2010 showed a high level of bun creatinine, but not a high level of potassium.thanks  <response>: Hello, high bun and creatinine usually indicates renal failure. Since shes had increased values in the past, its probably chronic renal failure CRF. CRF may cause increased potassium levels. The severity depends on how high they are. If her potassium is higher than 6mEqL then you should immediately contact your doctor for investigation. If the ratio of bun to creatinine is high 20 then she can try Chat Doctor. 