<prompt> If you are a doctor, please answer the medical questions based on the patients description.I am 57 yrs old and have been taking nebicard sm daily to control my BP. My cholesterol level is 233 and Triglylcerides is 211. I am not taking any other medicines. Kindly let me know if the triglycerides levels go up because of the BP medicine and if so what other medicine can I take as a substitute?  <response>: Hi Welcome. Nebicard SM contains a beta blocker Nebivolol a calcium channel blocker Amlodipine commonly prescribed to treat high BP. Increased cholesterol triglycerides appear to have been caused by Nebivolol. Beta blockers like Nebivolol can affect your cholesterol triglyceride levels causing a slight increase in their levels. These changes are often temporary. You shouldnt abruptly stop taking a beta blocker because doing so could increase your risk of a heart attack or other heart problems. Consult your treating doctor for an alternate, but a safer medication like Losartan to lower your high BP. Hope this will help. 