<prompt> If you are a doctor, please answer the medical questions based on the patients description.Lower back pain in center of back. Some times painful but since I stated taking GlucosamineChrondrotin it is not nearly as bad. I have trouble standing up right, especially f carrying any weight in my hands. At night I do not have pain but feel uncomfortable when sleeping on my back  <response>: Thank you for the question. As you have not mentioned your age or your sex both of which might be relevant, I have to say that there could be a few possibilities:1 lumbar spondylosis: disc protrusion from the lumbar spine maybe l4-l5. You should have a MRI and definitely show an orthopedic surgeion2 Arthritisoftenrheumatoid:Analgesics like ibuprofen 800 mg twice a day are the standard treatment for both. However, you should definitely have it checked out by your doctor. A simplex ray and blood tests for RA factor and anti-cccp should suffice3 Spinal TB: A rare complication especially if you live in a developed country. A MRI will give the picture 