<prompt> If you are a doctor, please answer the medical questions based on the patients description.Dear Dr. My Son has Glanzmanns Thromboaesthnia, a few days back he has caught cold with a bit of runny nose , is it advisable to give him Anti Histamine like cetrzine HydrochlorideRelent, Alreid, as it might cause nose bleed also, Please suggest any other anti allergic which do not cause nose bleed. Regards Ankur  <response>: Hello Anger, You have asked quite a difficult yet pertinent question. The GlibIlia def is functional, and can affect platelet function, and as far as studies are concerned with platelet and antihistamines it is usually a decrease in number though rare. Fexofenadine is a long acting 2nd generation antihistamine and the SPC of fexofenadine does not mention any such platelet problem. You are advised to discuss with your Hematologist if still in doubt. Thanks. 