<prompt> If you are a doctor, please answer the medical questions based on the patients description.I am in the US, but my friend lives in Rishikesh and she was diagnosed with TB. She was told she has a closed TB and nothing can be seen on the x-ray. She is now on her 3rd month of medication and was told to take it for a total of 10 months. I am very concerned about her and have several questions.  <response>: Hello ! Can you please mention in which organ in the body your friend was diagnosed to have TB ? Because TB can affect any organ n from head to toe. Since u mentioned X-ray, I presume you might be speaking about Pulmonary TB. For diagnosing pulmonary TB clinical patients presentation symptoms and signs, radiological Chest x-ray, high resolution CT appearance, microbiological sputum AFB, sputum CBN AAT testing findings need to be correlated. The common symptoms suggestive of TB are cough for more than 2 weeks duration not subsiding with routine antibiotics, fever with evening rise in temperature, bloody sputum hemoptysis, loss of appetite n loss of weight. Did your friend have any of these symptoms ? If yes then definitely investigations to rule out or rule in TB have to be proceeded with. Also, two things need to be kept in mind. One, not always chest x-ray show some abnormality in TB. If there is minimal lesion then only a HRCT chest can pick it up, and it can be missed on chest x-ray. Two, Since TB is common in India, at times, other diseases are wrongly diagnosed to be TB. Hence, its essential that you get the consultation with a qualified physician to ensure that diagnosis is correctly arrived at. As far as the treatment for TB is concerned, if this is the first time your friend is taking anti-TB medications then heshe has to take it for 6 months. If this is second time then the course will be for 8 months 