 Objective: The objective of this study is to estimate the proportion of positive tests in patients successfully treated for malaria smear negative at different time points in time after treatment, for three rapid diagnostic tests: SD Bioline Malaria Antigen P.f. catalogue number: 05FK50-02-4, CareStart Malaria HRP2 Pf catalogue number: G0141 and CareStart Malaria pLDH PAN catalogue number: G0111. The study will be carried out in two settings with known low and high malaria transmission levels in order to provide guidance of interpretation of a RDT positive result depending on the intensity of malaria transmission. 