 Any patient meeting the inclusion criteria including a Young Mania Rating Scale YMRS 37 total scores equal or superior to 20 and none of the exclusion criteria at the screening interview will be informed as well as hisher family about the study, and they will receive a Patient Information Sheet. A Consent form will be completed if they agree to take part in the study. Patients under section 12 who are unable to give informed consent: these patients will be asked for consent when they are better. The authorised psychiatrist will be able to give consent to treatment on their behalf until they are well. When they are well and are asked to give consent and they do not give consent, all information gathered on this patient will be removed. If the patient declines to consent to the study, shehe will be offered standard clinical care in EPPIC. 