 7. Adequate bone marrow,liver and renal function as assessed by the following laboratory tests conducted within 1 week before randomization. HB 90gL; ANC1.5×10E9L; PLT80×10E9L; ALT and AST 2.5×ULN; TBIL 1.25×ULN; Cr 1.25×ULN;CL45 mlmin. 