 4. Adequate hematologic ANC 1000mm3, platelet count 100,000mm3 and Hgb 8gmdL, renal serum creatinine 2mgdL, and hepatic functions total bilirubin 2 times, serum glutamate pyruvate transaminase SGPT or serum glutamate oxaloacetate transaminase SGOT 3 times the upper limit of the respective normal range. 