 Reduction of pain in the subgroup of patients with high pain index defined as patients that report 7-10, inclusive, on a 10-point Likert scale Reduction of pain in the subgroup of patients with moderate pain index defined as patients that report 3-6, inclusive, on a 10-point Likert scale Proportion of patients that are willing to repeat the procedure, if necessary Need for sedation or analgesia during colonoscopy Time to discharge 