 - Female subjects of childbearing potential 10 years of age must use a medically accepted method of contraception and must agree to continue use of this method for the duration of the study and for the follow-up time period. Acceptable methods of contraception include abstinence, barrier method with spermicide, intrauterine device IUD, or steroidal contraceptive oral, transdermal, implanted, and injected in conjunction with a barrier method. 