 1. Patient with an indication for PCI including angina stable or unstable, silent ischemia in absence of symptoms a visually estimated target lesion diameter stenosis of 70, a positive non-invasive stress test, or FFR 0.80 must be present, NSTEMI, or recent STEMI. For STEMI the time of presentation to the first treating hospital, whether a transfer facility or the study hospital, must be 24 hours prior to enrollment and enzyme levels CK-MB or Troponin demonstrating that either or both enzyme levels have peaked. 