 In healthy individuals, an after meal blood sugar level is very carefully controlled. Insulin the hormone that lowers blood sugar and glucagon hormone that raises blood sugar play a key role in maintaining this careful balance. In T1DM, there is a lack of insulin and failure of glucagon suppression keeping glucagon from being made too much. This leads to hyperglycemia high blood sugar right after you eat food. Also, glucagon is not controlled correctly after a meal. The glucagon, normally produced by the body, does not increase when a person with T1DM has a low blood sugar. This interferes with the balance between how much glucose is made and how much glucose is used. Therefore, glucagon fails to protect against low blood sugar in people with T1DM. This makes it very difficult to have normal blood sugars when someone has T1DM. This imbalance may be due to another hormone called amylin. This hormone may be too low in people with T1DM. 