 Android obesity contributes, via insulin resistance and endothelial dysfunction, to the development of cardiovascular atherosclerosis. It leads to poor quality of life. It is often associated with metabolic syndrome which includes, whatever the definitions used National Education Cholesterol Program, NECP Adult Treatment Panel III, ATP III or International Diabetes Federation, IDF, an increased waist measurement, an arterial high blood pressure and disorders of the glucide and lipid metabolism. The treatment of the current epidemic of obesity and metabolic syndrome in France 12.4 of obese and 14 of subjects with metabolic syndrome thus requires new therapeutic approaches. 