 In addition to antibody activity and antigen neutralization, benefits of Ig may include: inactivation of bacterial toxins endotoxin and exotoxins; increased clearance of lipopolysaccharide; stimulation of leukocytes and their bactericidal activity through mechanism of opsonization; reduction in the activity of the classical pathway of the complement; modulation of cytokine production by blood mononuclear cells; synergistic activity with antibiotics. 