 - Exclusion from this study also includes patients with a history of symptomatic autoimmune disease e.g., rheumatoid arthritis, systemic progressive sclerosis scleroderma, systemic lupus erythematosus, Sjogrens syndrome, autoimmune vasculitis e.g., Wegeners granulomatosis; motor neuropathy considered of autoimmune origin e.g., Guillain-Barre syndrome and myasthenia gravis; other CNS autoimmune disease e.g., multiple sclerosis 