 ---Data collection for Old cases: While new cases provide the information we are interested in, patients who have been treated for schizophrenia previously and with well documented records warrant a retrospective study. Although the psychiatric and physical conditions may not consist of all the variables we are interested in, they nevertheless point out a direction for the study of new cases. In brief, psychiatric and physical information of old cases are assessed by chart review and valued variables e.g., Brief Psychiatric Rating Scale BPRS, triglyceride levels, glucose levels, etc. and DNA will be collected and used in further pharmacogenetic studies. If possible, the variables of necessity described below will be collected by following a simplified guideline derived from the current protocol. 