 4. Cortical excitability: the cortical will be measured through the motor evoked potential MEP, short intracortical inhibition SICI and intracortical facilitation ICF. All the measures will be evaluated through transcranial magnetic stimulation Neurosoft, Russia. Initially, rest motor threshold RMT will be determined by finding the lowest stimulator output that elicit motor evoked potential MEP at least 50 microvolts μV. For RMT measure, a figure-eight coil connected to the magnetic stimulator held manually at 45 degrees from the midline, will be placed over the right primary motor cortex C3 - 1020 System. The short intracortical inhibition SICI and intracortical facilitation ICF will be evaluated by paired pulse transcranial magnetic stimulation. A subthreshold conditioning stimuli 80 of RMT and suprathreshold test stimuli 130 of RMT will be delivered at an interstimulus interval ISI of 2 milliseconds for SICI and 10 milliseconds for ICF. Ten stimuli will be applied at each condition unconditioned pulse and pairs of stimuli with ISI of 3 and 20 milliseconds. Stimuli order delivery will be pseudo-randomized and SICI and ICF will be expressed as conditioned stimulus percentage regarding unconditioned stimulus. The MEP value will be obtained through single pulse transcranial magnetic stimulation. Ten suprathreshold 130 of RMT stimuli will be delivered on primary motor cortex C3. 