 Lithium: Lithium will be started at 500mg per day on day one and will be increased to 500 mg bd from day 2. Serum lithium will be assessed on day 4, and the daily dose of lithium will be adapted accordingly. Serum lithium will be assessed again on day 7 and thereafter once or twice a week depending on the previous results. We will aim at keeping the lithium level between 0.5 and 1.0 mEql, ideally between 0.8 and 1.0 mEql. Higher levels are not recommended when lithium is prescribed along with antipsychotics 49 Chlorpromazine: Chlorpromazine will be started at 100 mgday orally and adjusted from day 2 by steps of 50 mg or 100 mg, upwards or downwards. Chlorpromazine will be continued for a minimum of 6 months, and will be interrupted according to the clinical state. 