 9. Demonstrate adequate organ function as defined in Table 1, all screening labs should be performed within 14 days prior to registration. 1 Hematological : Absolute neutrophil count ANC 1,500 mcL; Platelets 100,000 mcL; Hemoglobin 9 gdL or 5.6 mmolL. 2 Renal: Serum creatinine 1.5 X upper limit of normal ULN OR Measured or calculated creatinine clearance GFR can also be used in place of creatinine or CrCl 60 mLmin for subject with creatinine levels 1.5 X institutional ULN. 