 In addition, investigator will evaluate the association between each BA species and serum total glucagon like peptide-1 GLP-1 or fibroblast growth factor-19 FGF-19 concentrations to determine if the specific BAs profile is related with total GLP-1 or FGF-19 concentration in serum. Investigatr also evaluates the correlation between each BA species and metabolic profiles and oxidative stress marker to find possible roles of each BA component in glucose metabolism. 