 Dose proportionality of CD24Fc plasma PK parameters AUCs and Cmax was assessed using the power model: y a DoseB, where y denotes the PK parameter being analyzed and a depends on subject. Dose proportionality implies that B 1 and was assessed by estimated β along with its 90 confidence interval CI. The exponent, B, in the power model was estimated by regressing the log-transformed PK parameter on log-transformed dose. 