 The study is a prospective, multi-center, Phase I study of the Evalve Cardiovascular Valve Repair System CVRS in the treatment of mitral valve regurgitation. A minimum of 20 patients will be enrolled an additional maximum of 12 roll in-patients, a maximum of 2 per site, may be enrolled and analyzed separately. Patients will undergo 30-day, 6 month and 12 month clinical follow-up. 