 The aim of the USECARE project is to improve and test SENACA, an ICT-based self-management support system for chronically ill patients and informal caregivers. 60 end-users will be instructed to use SENACA for approx. 3 months in Israel and Norway. Amongst others, clinical and behavioural outcomes will be recorded. Additionally, SENACAs usability will be evaluated to determine its potential future scalability. 