 - Cytogenetic relapseprogression defined as the appearance in one or more metaphases from bone marrow or peripheral blood cells of either a non-constitutional cytogenetic abnormality identified in at least one cytogenetic study performed prior to transplant or a new abnormality known to be associated with leukemia; for CML, an increase in the number of Ph metaphases from bone marrow or peripheral blood between two consecutive samples after engraftment, or an increase in the percentage of BCRABL cells by fluorescence in situ hybridization FISH between two consecutive samples after engraftment 