 7. Unstable or uncontrolled thyroid disease 8. Treatment with interferon- andor ribavirin within the previous 12 months 9. Presence of clinically significant cryoglobulinemia vasculitis e.g. skin rash, arthritis, or renal insufficiency due to cryoglobulinemia 10. Presence or history of autoimmune hepatitis, alpha-1-anti-trypsin deficiency, genetic hemochromatosis, Wilson disease, drug- or toxin-induced liver disease, alcohol-related liver disease, primary biliary cirrhosis, or sclerosing cholangitis. 