 For our own study, we chose to look at two forms of CAM, Reiki and relaxation response therapy RRT. These two were chosen as we had some evidence of utilization within our own cancer population. Reiki treatment is given at the Zakim Center. In the four years since the Zakim Center opened, there have been approximately 300 patient visits for Reiki therapy. Reiki is an energy healing method discovered in the late 1800s in Japan. The word Reiki is made up of two Japanese words: Rei, an unlimited universal power of force that acts in all created matter; and Ki, a living spirit energy that applies to the physical principle of life. Licensed Reiki Masters perform Reiki. All of the Reiki Masters at the Zakim Center are also registered nurses. Subjects often express an enhanced sense of well-being and relaxation after a Reiki session, according to the Reiki practitioners, and most return for at least one more session. Led by Susan DeCristofaro, the Reiki experience at the Zakim Center has been standardized. Here, Reiki is given for acute and chronic pain, headache, depression, anxiety, nausea, vomiting and insomnia. The fee for a Reiki session is 55.00. However, the effects of receiving Reiki have not been subjected to rigorous scientific study. In a review of energy healing, eleven studies looking at Reiki were reviewed. Of these, seven showed a beneficial effect,18-22 three showed no effect21,23,24 and one had a negative effect.25 We believe, after review of this data, that there are many unanswered questions about this treatment. 