 Prior to being enrolled in this study, they will undergo an evaluation to determine eligibility. The study doctor will obtain a complete medical history, complete a physical examination including blood pressure and heart rate. The doctor will also obtain a baseline ECG as well as blood tests approximately two tablespoons of blood. In order to decrease the effects of food, exercise and the sleepwake cycle variability, all blood samples must be taken between 8AM - 10AM and patients will need to fast no food or drink for 10 hours prior to the blood test. Patients will also need to strain from working out prior to the blood test. The study will ask for a list of current medications. Patients will not be eligible if they have a history of or now require long-term anticoagulant blood thinner therapy i.e. Coumadin or anything patients may be taking to prevent blood clots have an allergy to bevacizumab or any other drugs used in the study. 