 Potential Risks Grafton was associated with acute tubular necrosis in an animal study done with athymic rats 2,9. This studys authors suggested to restrain the use of DBM in children or patients with renal diseases 2,9. These findings have not been corroborated with any other study at the moment and there are some other points to be analyzed such as the associated materials used with Grafton. In any case, we will not include patients with any type of renal disease or patients under the age of 18 years old in the present study. 