 You will receive an investigational research cancer vaccine every 3 weeks for a total of 4 treatments. It is given by injection underneath your skin in an extremity leg or arm. A vaccine is a compound designed to strengthen the immune system the cells and substances that protect the body from infection and foreign matter to fight an illness such as infections or cancer. This vaccine is called NY-ESO-1 protein. NY-ESO protein an antigen, which is a compound that is recognized by the immune system is found in many cancers. Proteins such as NY-ESO-1 and their fragments are the targets the immune system needs to recognize cancer cells. If the immune system can recognize these antigens foreign substances it may be able to kill the cells that carry them. NY-ESO-1 can be found at different stages of cancers, and is likely to be expressed shown at some point in the lifecycle of these types of cancer that are eligible for this study. Therefore this study tries to boost strengthen the immune system toward NY-ESO-1 protein regardless of whether it is found in your tumor or not. 