 In France, 100 to 120 pediatric cases of DHUS are reported each year. STEC infection was demonstrated in 85 of cases. In 50 of cases, one or more persons of the same family have STEC diarrhea without HUS. The death rate in the acute phase is about 2 and 50 of DHUS requires dialysis. The predictive factors of a poor outcome are an anuria for more than 8 days a neutrophil count20000mm3, a severe bowel disease or central nervous system CNS involvement Scheiring et al. 2008. In 65-80 of cases, a seemingly ad integrum recovery of renal function was observed within the first year after D HUS onset. However, DHUS is responsible for a nephron loss that could lead to hypertension, proteinuria and chronic renal failure in the long term. A study performed on 218 patients undergoing DHUS in the chidhood, highlighted the presence of renal sequelae in nearly 65 of them with a median follow-up of nearly 20 years. Fila et al, submitted. 