 - All patients receiving a T cell depleted BMT from a mismatched family member or unrelated donor will be eligible for this protocol. In addition, patients receiving a matched sibling transplant or T replete transplant may be eligible if they are at high risk of developing EBV LPD because of their underlying disease e.g Wiskott-Aldrich or Ataxia Telangiectasia or have a past history of EBVLPD or other EBV associated malignancy. 