 - Current treatment with disease-modifying antirheumatic drug DMARDsimmunosuppressive agents including MTX, cyclosporine, mycophenolate, tacrolimus, gold, penicillamine, sulfasalazine or hydroxychloroquine within 2 weeks prior to the baseline Randomization Visit or azathioprine, cyclophosphamide within 12 weeks prior to baseline Randomization Visit or leflunomide within 8 weeks prior to the Randomization Visit, or 4 weeks after cholestyramine washout. 