 - Take physician-prescribed medications that may interact with indomethacin: 1 cardiovascular drugs e.g. angiotensin-converting-enzyme inhibitor ACE inhibitors, angiotensin II receptor blockers ARBs, Diuretics; 2 drugs that would increase bleeding risk e.g. warfarin, heparin, clopidogrel, rivaroxaban, other NSAIDs; or 3 drugs associated with increased renal toxicity e.g. cyclosporin, tacrolimus 