 This prospective, single-arm multi-center study will provide clinical data in an observational setting using the Echelon FlexTM 45 and 60 Powered ENDOPATH Stapler Articulating Endoscopic Linear Cutters study Endocutter. Individuals undergoing VATS lobectomy for suspected or confirmed Non Small Cell Lung Cancer NSCLC, or individuals undergoing VATS diagnostic wedge resection in accordance with their institutions Standard of care SOC, and who meet study entry criteria, may be enrolled. 