 - Adequate liver function as shown by; serum bilirubin 1.5 x Upper Limit of Normal; International Normalized Ratio 1.3; alanine aminotransferase and aspartate aminotransferase 2.5 x Upper Limit of Normal - Adequate renal function: serum creatinine 1.5 x Upper Limit of Normal - Fasting serum cholesterol 300 mgdL OR 7.75 mmolL and fasting triglycerides 2.5 x Upper Limit of Normal. NOTE: In case one or both of these thresholds are exceeded, the patient can only be included after dyslipidemia treatment initiation. 