 Study Methodology- Critical to any environmental epidemiology research is coordination between experts in exposure assessment and health outcomes. This study will be a two year collaborative effort between the School of Public Health at the University of Haifa and the Faculty of Civil and Environmental Engineering at the Technion. Exposure measures will come from the Haifa District Municipal Association for the Environments HDMAE network of 15 monitoring stations in the region. HDMAE also monitors a number of meteorological covariates ie. maximum and minimum temperatures, mean humidity, and mean barometric pressure which will be incorporated into exposure modeling. 