 - Uncontrolled hypertension systolic 180mm Hg or diastolic 110mm Hg - History of bipolar disorder or psychosis - Myocardial infarction or other serious cardiac problem in the previous 4 weeks - History of diagnosed anorexia andor bulimia - Diagnosis of Alcohol Dependence in the previous 6 months by participant self-report or drinking 6 or more drinks on six or more days a week - History of seizure andor serious head injury involving loss of consciousness - Use of contraindicated medications MAO inhibitors, bupropion, lithium, anticonvulsants, antipsychotics - Currently pregnant or breast-feeding - Unwilling to use effective contraception during the treatment phase - More than one participant from the same household - Allergic reactions to 3 or more classes of drugs 