 Expected results: The investigators expect that at the end of the study most of the recipients will have been able to have a successful rejection and a minor group around 30 will not be able to do it because of rejection. Then baseline mRNA samples will be used to perform whole genome microarrays. Using bioinformatics procedures the investigators will make an attempt to establish a differential gene expression among those with a successful conversion and those that develop rejection. This will allow the investigators to determine the smallest set of genes able to discriminate between those patients. Gene expression will be also correlated with peripheral blood cell immunophenotyping and clinical variables. 