 Future Directions: This work will be coordinated with a series of preclinical studies planned in the Davis lab. The effects of pharmacologic probes on fear conditioning and fear inhibition will be explored in normal controls as a potential method for identifying new pharmacologic treatments for PTSD. Treatment effects on fear conditioning and inhibition will be studied in PTSD subjects. Data from the current project will serve as pilot data for future NIH R01 and VA Merit Review grant submissions. 