 6. Adequate function of major organs bone marrow, heart, lungs, liver etc.. WBC 3,500mm3. Hb 10.0 gdl. Platelet count 100,000mm3. GOT and GPT 2.5times the upper limit of normal excluding liver metastasis. T-Bil 3.0mgdl. Creatinine within the upper limit of normal. Normal ECG not considering clinically unimportant arrhythmias and ischemic changes. 