 Patients receive gemcitabine hydrochloride and paclitaxel albumin-stabilized nanoparticle formulation intravenously IV on days 1, 8, and 15. Patients also receive metformin hydrochloride orally PO twice daily BID starting day -6 and dietary supplement PO BID starting day -3. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. 