 4. Patients must be able to swallow and tolerate oral medications and not have gastrointestinal illnesses that would preclude absorption of AZD1775 e.g. uncontrolled nausea, vomiting, or diarrhea; malabsorption syndrome; ulcerative disease. Note: Patient may not have a percutaneous endoscopic gastrostomy PEG tube or be receiving total parenteral nutrition TPN. 