 40 patients attending IVF center during 2013 2014 were fulfilling criteria of poor response and they failed to go through OPU as they gave 3 mature follicles on a dose of 300U GN or more. All patients were revised for history, examinations and investigations, including age, type and duration of infertility, day 3 FSH, Day 3 E2, AMH, AFC All patients were 35 years old ore more We exclude patient 44ys ,AMH 0.3ngml,FSH 13, also patients of DM, endometriosis, general disease were excluded, any local uterine anomalies were excluded. 