 On the human being, the German outbreak of DHUS in O104H4 helped highlight the importance of an early treatment with azithromycin on the eradication of carriage of the bacteria as well as the eradication of Stx in stool Nitschke et al. 2012. In addition, preliminary data from a retrospective study of DHUS in Robert Debré hospital showed a lower incidence of severe digestive tract impairment in patients with DHUS who received treatment with azithromycin compared to the control group unpublished data. 