 Hematology: neutrophils 2.0x109l; platelets 100x109l; hemoglobin 10 mgdl; Hepatic function: total bilirubin 1 upper normal limit UNL; SGOT and SGPT 2.5 UNL; alkaline phosphatase 2.5 UNL. If values of SGOT and SGPT 1.5 UNL are associated to alkaline phosphatase 2.5 UNL, patient is not eligible; Renal function: creatinine 175 mmoll 2 mgdl; creatinine clearance 60 mlmin. 