 The calculation of the sample size with an alpha error of 5, statistical power of 80, standard deviation of 8 mmHg, and maximum acceptable absolute difference of 6 mmHg diastolic BP, indicated the necessity to study 36 patients per group SNB versus DBB. However, considering a potential rate of 10-15 dropout or loss to follow-up, 40 will be considered for each group. The difference of 5 mmHg diastolic BP has been achieved, on average, in clinical trials that have demonstrated the advantage of one drug over placebo or other non-pharmacological treatments in the prevention of major cardiovascular outcomes. 