 The Psychobiology of Recovery in Depression-III Somatic Symptom Scale PRD-III is a 24 item, side effects scale developed for a longitudinal depression study. The PRD-III covers a wide range of common medication side effects and can be quickly and easily administered by a clinician. The PRD-III will be administered at every visit. Asthma-related quality of life will be assessed with the Mini-AQLQ, a 15 item, self-administered scale measuring functional impairments troublesome to adult asthma patients. Mini-AQLQ showed good responsiveness, reliability, and construct validity compared to the longer 32 item version. Both versions of the Mini-AQLQ correlate well with SF 36 mental and physical subscales and ACQ scores asthma symptoms, but not with spirometry or beta-agonist use. The Mini-AQLQ will be administered at baseline, week 4, week 8, week 12, and at exit or if continued, week 28. General functioning will be assessed with the 36-Item Short Form Health Survey SF-36, a self-reported tool used to assess physical and mental functioning. The scale consists of summary measures of physical and mental health that can be further divided into scales for physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health. Scores above the normative score of 5010 indicate better than average functioning while scores below 50 suggest below normal functioning. The SF-36 will be administered at baseline, week 4, week 8, week 12, and at exit or if continued, week 28. 