 Three times during hisher participation in the sub-study, study investigators will ask the subject to wear a sleep monitor device called an Actigraph: once following enrollment but prior to randomization, once following the end of treatment, and once three months following the end of treatment. The subject would wear the actigraph Actiwatch , Philips Respironics, Bend, OR like a wrist watch on hisher non-dominant arm. The device will measure how long the subject sleeps, as well as the overall quality of hisher sleep. The subject will wear the actigraph at all times during the same 7-day period she is completing the sleep diary except for when the subjects is participating in activities that might get the actigraph wet like swimming, showering, or bathing. 