 Stage 2, Kampala: HIV-1 infected males or females of at least 18 years, treated with a stable efavirenz based combination regimen tenofovir emtricitabine or tenofovirlamivudine or zidovudinelamivudine for at least the preceding 12 weeks, with a CD4 T-cell count 100 cellmm3, co-infected with TB and undergoing anti-TB treatment with rifampicin and isoniazid-containing regimens. 