 When a subject is scheduled for a dressing change in the burn treatment room, venous blood samples of 10 mL will be obtained from an indwelling catheter 4-12 hours before and after the procedure to evaluate the level of IL-1β and IL-6 in the serum. Blood samples will be centrifuged for 15 minutes at 3000rpm with plasma immediately separated and stored at -80F. Enzyme-linked immunosorbent assays ELISA will be used to determine IL-1β and IL-6 concentrations after all subjects have completed the study. 