 This clinical trial studies giving radiation therapy to the liver in patients with uveal eye melanoma who have a specific chromosome loss monosomy 3 or are DecisionDx Class 2 and therefore more likely to have their disease spread from the eye to the liver. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Early radiation to the liver may reduce the development of tumors in the liver and the overall risk of disease recurrence. 