 - Participants must have a 12-lead electrocardiogram ECG consistent with normal cardiac conduction and function at screening, including: a Sinus rhythm heart rate between 45 and 100 beats per minute bpm, inclusive; b QT interval corrected for heart rate according to Fridericia QTcF interval between 350 milliseconds ms and 430 ms for male participants, and between 350 ms and 450 ms for female participants inclusive; c QRS interval of 110 ms; d PR interval 200 ms; e Morphology consistent with healthy cardiac conduction and function 