 Potentially resectable Stage III or IV squamous cell carcinomas of the head and neck HNSCC are treated by operation and adjuvant radiotherapy. The 5-year survival rate is approximating 30. Recurrence typically occurs within 3 years, 60-80 in locoregional sites, and 20-30 systemically. Patients who are found to have tumors at the margins of surgical specimens far particularly poorly. 