 I. To establish baseline epidermal growth factor receptor EGFR, truncated EGFR EGFRvIII, phosphorylated EGFR pEGFR and related signal transduction pathway protein expression levels such as the mitogen activated protein kinase p-ERK, AKT phosphorylation and Her2neu in tumor samples obtained pretreatment, and to correlate these with achieving pCR. 