 1. Patients with a life expectancy 2X normal for age 7. Patients with known allergy to rat serum products 8. Patients with a Lansky score 60 or Karnofsky score 60. 9. Patients with severe infection that on evaluation by the PI precludes ablative radiochemotherapy or successful transplantation. 10. Patients with sever personality disorder or mental illness. 11. Patients with documented HIV positivity 12. Pregnant or lactating females 