 Aquamin is composed of multiple minerals and the active ingredient for the complex is difficult to determine. A number of the minerals in Aquamin may have anti-inflammatory and anti-oxidant properties which might directly andor indirectly influence the efficacy of this unique complex 7,8,9. While the prominent mineral present in Aquamin is calcium dosage 80 Ca U.S RDA, its role in joint health is unclear. Magnesium however, was given at the daily dosage providing 14 male to 18 female U.S. RDA 6 and over the course of this study, this increased consumption of magnesium may have influenced OA symptoms by affecting the utilization of calcium or by potentially reducing inflammation around the affected joint. Both manganese and selenium were given at the daily dosage providing up to 16 and 4 of their RDA respectfully. Both of these trace minerals have been reported to reduce the appearance of osteoarthritic lesions and reduce the severity of symptoms in OA 8,9. 