 Three times during hisher participation in the sub-study, study investigators will ask the subject to keep a sleep diary: once following enrollment but prior to randomization, once following the end of treatment, and once three months following the end of treatment. The subject will complete a diary entry twice a day morning and night for seven days. In the morning, the subject would answer basic questions about hisher sleep during the previous night, including time the subject thinks she fell asleep, the quality of hisher sleep, and any other experiences that might have affected hisher sleep. In the evening, the subject will answer questions about how the subject felt that day, any problems she experienced such as illness or discomfort, and basic activities she participated in like going to work, napping, drinking caffeinated beverages, etc. 