 The first eight patients will receive 0,055 mgkg 2-IB every 4 hours intravenously, 6 times in total part A. The second eight patients cohort B will receive 0,165 mgkg every 4h iv, 6 times in total. The third eight patients cohort C will receive 0,5 mgkg every 4h iv, 6 times in total. Medication has to be given as soon as possible and within 6h after OHCA. Escalation to the next dose level will only be done after pharmacokinetic analyses have performed, no relevant safety issues have been encountered, and the DSMB approves to move to the next dose level. 