 For appropriate judgment of response, secure standard endoscopic ultrasonography EUS with fine needle aspiration FNA biopsy of potential suspected lesions, both nodal or residual tumor, seen on PETCT or DWIMRI or during EUS will be performed 2 weeks before surgery, approximately 6-10 weeks after nCRT and compared with the situation at primary staging. Patients with clinical complete response cCR resembling pathologic response pCR ypT0N0 after nCRT may refrain from surgical resection and related morbidity and mortality. However, patients without early 2wk after commencement response during nCRT course may not benefit from nCRT. 