 7. Female patients cannot be pregnant or lactatingbreast-feeding and will either be postmenopausal female patients who state they are postmenopausal should have had cessation of menses for 1 year and have serum follicle stimulating hormone FSH levels 40 mIUmL and estradiol 20 pgmL, surgically sterile including bilateral tubal ligation, salpingectomy with or without oophorectomy, surgical hysterectomy, or bilateral oophorectomy with or without hysterectomy for at least 3 months prior to Screening, or will agree to use, from the time of Check-in Day -1 until 90 days following the last dose of study drug, the following forms of contraception: double-barrier method, hormonal contraceptives, barrier with spermicide, diaphragm or cervical cap with spermicide, intrauterine device, oral, implantable, or injectable contraceptives, or a sterile sexual partner. All female patients will have a negative urine or serum pregnancy test result prior to enrollment in the study. 