 Eligible patients with painful osteoporotic compression fractures of the spine are divided into two groups. Each enrolled patient will have the vertebroplasty procedure; however one group of patients will have the vertebroplasty procedure using polymethylmethacrylate PMMA a Food and Drug Administration FDA-approved bone cement and the other group of patients will have the vertebroplasty procedure using a relatively new investigational biomaterial called Cortoss. 