 For the second issue, the necessity for acclimatisation time and caregiver attention, very elegant solutions are available to provide this at home too. A longer initiation period can better be met at home, in a trusted environment for the patient, saving the disadvantages and costs of a prolonged hospital stay. With modern technologies the necessary caregiver attention can also be provided at home. Monitoring data can be sent to caregivers on daily basis by telemonitoring. This proven technology enables caregivers to make on daily basis, on distance, decisions regarding the NIV initiation process, which will be discussed with the patient by frequent telephone calls. This so called telemedicine has already been shown to be a valuable and promising tool to monitor and to adjust treatment of patients already established on chronic NIV at home. In our home NIV initiation pilot project in neuromuscular patients, the investigators were the first to show in a RCT that this technology was very feasible to use for NIV initiation at home. 