 Currently approved antiretroviral medications target either the HIV viral reverse transcriptase RT, Nucleoside Reverse Transcriptase Inhibitors NRTIs and Non-Nucleoside Reverse Transcriptase Inhibitors NNRTIs or the viral protease, Protease Inhibitors PIs or inhibit viral fusion with target cells Fusion Inhibitors. A regimen using a combination of these agents is considered the standard of care and, when effective, results in suppression of the virus below the detection limits. 