 9. Adequate hematologic function: 1.Absolute neutrophil count ANC 1.5x109L; 2.Platelet count 100x109L; 3.Hemoglobin 10.0 gL. 4.International normalization ratio INR or prothrombin time PT 1.5 x ULN, unless the subject is receiving anticoagulant therapy, in which case PT and partial thromboplastin time PTT activated PTT aPTT must be within therapeutic range of intended use of anticoagulants 