 - Known active hepatitis B e.g., hepatitis B surface antigen HBsAg reactive or hepatitis C e.g., hepatitis C virus HCV ribonucleic acid RNA qualitative is detected; NOTE: patients with active hepatitis B defined by hepatitis B surface antigen positivity or core antibody positivity in the presence of hepatitis B deoxyribonucleic acid DNA are not eligible for this study; patients with a positive hepatitis B core antibody but with negative hepatitis B DNA may participate, but must have hepatitis serologies and hepatitis B DNA monitored periodically by the treating physician 