 - is willing to limit aspirin use to or 120 mg po per d typical cardioprotective dose in India or or 80 mg po per d typical cardioprotective dose in the US for the duration of the study, and is willing to abstain from chronic use of all NSAIDs and COX-2 inhibitors for duration of study. Chronic use of NSAIDs is defined as a frequency of or 3 timeswk AND for more than a total of 14 ds a yr. 