 Intravascular imaging with intravascular ultrasound IVUS or optical coherence tomography OCT is widely considered the gold standard for scaffold optimal implantation, although currently it is not routinely used. The use of intravascular imaging techniques before and after BVS implantation may help to avoid inadequate expansion and apposition of the scaffold struts. Subintimal calcifications detected with IVUS or OCT require adequate lesion preparation before stent deployment. This is particularly crucial for patients receiving BVS, where the goal of lesion preparation is to facilitate scaffold delivery, reduce plaque shift and to allow optimal scaffold expansion. OCT with its greater resolution enables to assess the scaffold integrity, apposition and the presence of thrombus or edge dissections. 