 Methods:: The investigators are to study approximately 40 subjects, both normal, i.e. comparison group and patients with a variety of pulmonary conditions that effect oxygen saturation. The investigators will compare the oxygen saturation of each subject as measured with Oxitone 1000 device and with the oxygen saturation as measured with calibrated conventional FDA approved pulse oximeter predicate. The Reference. No treatment decision will be made utilizing the results of the tested device. 