 PR IHC: Five micron paraffin embedded core tissues will be processed for standard PR IHC assays using FDA approved antibodies and quantified as described previously. Two pathologists Dr. Gonzalez and Dr. May, supervised by Dr. Molinolo will quantify and score the IHC staining. The pathologists will inform the PR score to Dr. Liguori, 72 hs after biopsy who will include the record at the patient CRF. 