 Bleeding under cardiopulmonary bypass CPB is one of the most common complications in patients undergoing pediatric cardiac surgery. The inflammatory response produced during and after CPB is a factor that adds significantly to the morbidity after cardiac surgery. A number of factors have been shown to be involved inducing the inflammatory response. These include complement system activation3 and activation of inflammatory cytokines, especially IL-1 IL-64, IL-8 and TNF alpha. 