 - mild to moderate stable COPD Global Initiative for Chronic Obstructive Lung Disease GOLD Stage I and II according to the 2010 GOLD guidelines a post-bronchodilator forced expiratory volume in the first second FEV1 80 of predicted for stage I and 50 FEV1 80 of predicted for stage II, with a post-bronchodilator FEV1forced vital capacity FVC ratio 0.70 at screening 