 Intracerebral hemorrhage ICH in patients with non-valvular atrial fibrillation NVAF poses a particular dilemma for thromboprophylaxis. Left atrial appendage occlusion LAAO is a non-pharmacological approach to prevent cardiac embolism in NVAF. The risk-benefit ratio of LAAO in patients with NVAF after ICH is unknown. The aim of STROKECLOSE is to assess the effect of LAAO to reduce the incidence stroke, bleeding and cardiovascular mortality in patients with NVAF and prior ICH. 