 Exclusion criteria who are classified as very high risk group 2.1 Philadelphia chromosome or bcrabl rearrangement 2.2 Chromosome 45 by cytogenetics 2.3 Induction failure Day 28 M3 marrow 25 blasts 2.4 t4:11 as identified by cytogenetics, FISH or molecular studies 2.5 Early T-cell precursor leukemia 2.6 Down syndrome ALL 