<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:An 8-month-old infant is brought to the physician by his mother because of a 1-month history of progressive listlessness. His mother says, He used to crawl around, but now he cant even keep himself upright. He seems so weak! Pregnancy and delivery were uncomplicated. Examination shows hypotonia and an increased startle response. Genetic analysis show insertion of four bases TATC into exon 11. Further evaluation shows decreased activity of hexosaminidase A. Which of the following mutations best explains these findings?? A: Frameshift, B: Missense, C: Nonsense, D: Silent, E: Splice site,  <response>: This is a clinical vignette describing an 8-month-old infant with progressive weakness and hypotonia. The history and exam findings are consistent with a neurodegenerative disorder. Genetic analysis revealed an insertion mutation in exon 11 of a gene, leading to decreased activity of hexosaminidase A. This suggests a frameshift mutation, which can lead to a downstream premature stop codon and nonfunctional protein product. The other mutation types would be less likely to completely disrupt protein function.A: Frameshift 