<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 37-year-old woman, G1P0, visits her gynecologists office for a routine prenatal checkup. During her quadruple screening test, her alpha-fetoprotein levels were increased while the β-hCG and pregnancy-associated plasma protein were decreased. There is also evidence of increased nuchal translucency on the scanning of the male fetus. A confirmatory test indicates signs of a genetic syndrome. The woman is counseled that her child will most likely have a severe intellectual disability. Physical features of this condition include polydactyly, cleft palate, micrognathia and clenched fists. This genetic condition also affects the formation of the brain and can lead to stillbirth. Most babies do not survive beyond the first year of life. Which of the following is responsible for this type of genetic syndrome?? A: In utero infections, B: Error in metabolism, C: Genomic imprinting, D: Nondisjunction of chromosomes, E: Autosomal dominant genes,  <response>: Based on the description in the question stem, this seems to be a case of a genetic syndrome caused by chromosomal abnormalities. The key findings that point to this include:- Abnormal quadruple screening results altered AFP, β-hCG, and PAPP-A - Increased nuchal translucency on ultrasound- Severe intellectual disability - Characteristic physical features like polydactyly, cleft palate, micrognathia- Brain malformations- High risk of stillbirth- Low survival beyond first yearThese features are most consistent with a chromosomal trisomy syndrome like Trisomy 13 or 18. The other answer choices of infections, metabolic errors, genomic imprinting issues, or autosomal dominant genes would not fully explain this constellation of findings.D: Nondisjunction of chromosomes 