<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 16-year-old teenager is brought to the pediatricians office by her mother. The mother expresses concerns about her daughters health because she has not achieved menarche. The daughter confirms this and upon further questioning, denies any significant weight loss, changes in mood, or changes in her appetite. She denies being sexually active. She is a good student who works hard and enjoys competing in sports. She was born via spontaneous vaginal delivery at 39 weeks. There some discussion about mild birth defects, but her mother never followed up and can not recall the specifics. Her vaccines are up to date and she has met all developmental milestones. Past medical history and family history are benign. She has a heart rate of 90min, respiratory rate of 17min, blood pressure of 11065 mm Hg, and temperature of 37.0C 98.6F. On physical examination, the patient is short in stature at the 33rd percentile in height. Additionally, she has some excessive skin in the neck and has a broad chest with widely spaced nipples. A urine pregnancy test is negative. Which of the following genetic abnormalities is the most likely cause of this patients condition?? A: 45,X0, B: 45,XX, t14;21, C: Trisomy 21, D: 47,XXY, E: 21-hydroxylase deficiency,  <response>: This is a question about identifying the most likely genetic cause of delayed puberty and short stature in an adolescent girl. The key findings in the stem are:- 16 year old girl with no menarche - No significant weight loss, mood changes, appetite changes- Denies being sexually active- Good student and athlete- Born at 39 weeks, possible mild birth defects at birth- Normal development and benign medical history otherwise- Vital signs normal- Short stature, excessive neck skin, broad chest with wide nipple spacing- Negative pregnancy testThe delayed puberty and short stature along with the physical exam findings of excessive neck skin, broad chest, and wide nipple spacing point towards Turner syndrome 45,X0 as the most likely diagnosis. The other choices do not fit with the clinical presentation.A: 45,X0 