<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 29-year-old woman presents for an annual flu shot. She has no symptoms. Past medical history is significant for mild rheumatoid arthritis, diagnosed 3 years ago and managed with celecoxib and methotrexate. Current medications also include a daily folate-containing multivitamin. She also had 2 elective cesarean sections during her early 20s and an appendectomy in her teens. Her family history is insignificant. The patient does not consume alcohol, smoke cigarettes, or take recreational drugs. Her physical examination is unremarkable. Recent laboratory studies show:Hemoglobin Hb 14.2 gdLMean corpuscular volume MCV 103 fLSince she is asymptomatic, the patient asks if her medications can be discontinued. Which of the following diagnostic tests is the most useful for monitoring this patients condition and detecting the overall inflammatory state of the patient at this time?? A: C-reactive protein CRP, B: Rheumatoid factor RF, C: Anti-cyclic citrullinated peptide anti-CCP, D: Erythrocyte sedimentation rate ESR, E: Complete blood count,  <response>: This question is asking about the most useful diagnostic test for monitoring the inflammatory state in a patient with rheumatoid arthritis RA who is on methotrexate and celecoxib. The key points from the stem are:- 29 year old woman with mild RA on methotrexate and celecoxib- Wants to know if medications can be discontinued - Physical exam is unremarkable- Labs show normal Hb and slightly elevated MCVThe answer choices give different diagnostic tests that could be used to monitor RA disease activity and inflammation. Rheumatoid factor RF and anti-CCP are autoantibodies found in RA. However, they do not fluctuate with disease activity and are therefore not useful for monitoring. ESR and CRP are acute phase reactants that increase with inflammation. Of these two, CRP is more sensitive and better correlates with disease activity in RA.Complete blood count can indicate anemia but does not directly assess inflammation. Therefore, CRP is the best answer. It will help determine if medications can be discontinued by providing a quantitative measure of the patients inflammatory state.A: C-reactive protein CRP 