<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 49-year-old woman presents to the primary care physician with complaints of recurrent episodes of right upper abdominal pain for the past 2 years. She is currently symptom-free. She mentions that the pain often occurs after a heavy fatty meal and radiates to her right shoulder. On examination, the patient has no tenderness in the abdomen and all other systemic examination is normal. Blood work shows:Leukocyte count 8,000mm3Total bilirubin 1.2 mgdLProthrombin time 12 sAspartate transaminase 58 IULAlanine transaminase 61 IULSerum albumin 4.1 gdLStool occult blood negativeUltrasonography of the abdomen shows a thickened gallbladder wall with few gallstones. A hydroxy iminodiacetic acid HIDA scan was done which demonstrated non-filling of the gallbladder and a minimal amount of tracer in the common bile duct. Which of the following best describes a histopathological feature in the gallbladder described in this case?? A: Neutrophilic infiltration with vascular congestion and fibrin deposition in the gallbladder, B: Minimal lymphoid aggregates, C: Entrapped epithelial crypts seen as pockets of epithelium in the wall of the gallbladder, D: Hyalinized collagen and dystrophic calcification in the submucosal layer, E: Abnormal deposits of cholesterol ester in macrophages in the lamina propria,  <response>: This is a clinical vignette describing a 49-year-old woman with recurrent episodes of right upper abdominal pain after heavy fatty meals that radiates to her right shoulder. She has no abdominal tenderness on exam. Lab tests show mildly elevated liver enzymes and normal bilirubin. Imaging shows gallstones and thickened gallbladder wall, and a HIDA scan shows non-filling of the gallbladder. The question asks to identify the histopathological feature that would be expected in this patients gallbladder. Based on the clinical history of biliary colic after fatty meals and imaging showing gallstones and non-filling gallbladder, this patient likely has chronic cholecystitis. The choices describe various histopathological changes that can occur in cholecystitis. Choice A describes acute inflammation. Choices B, D and E do not match chronic cholecystitis. Choice C describes Rokitansky-Aschoff sinuses, which are pockets or cysts formed from entrapped epithelial crypts and are a classic histological feature of chronic cholecystitis.C: Entrapped epithelial crypts seen as pockets of epithelium in the wall of the gallbladder 