<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 55-year-old woman comes to the physician because of fever, chills, headache, and nausea over the past 3 days. Nine months ago, she returned from a vacation in Indonesia where she had experienced similar symptoms and episodic fever. She was treated with chloroquine and recovered uneventfully. Her temperature is 39.1C 102.4F, pulse is 97min, and blood pressure is 12385 mm Hg. Physical examination shows scleral icterus. The abdomen is soft; bowel sounds are active. Neurologic examination is unremarkable. Her hemoglobin concentration is 10 gdL. A photomicrograph of a peripheral blood smear is shown. Which of the following is the most likely cause of the recurrence of symptoms in this patient?? A: Decline in circulating antibodies, B: Reinfection by Anopheles mosquito, C: Natural drug resistance, D: Reactivation of dormant liver stage, E: Dissemination within macrophages,  <response>: This is a clinical case scenario question involving a 55-year-old woman with recurrent fever, chills, headache, and nausea after traveling to Indonesia 9 months ago. She was previously diagnosed and treated for malaria with chloroquine. The key findings are:- Recent travel to malaria-endemic area - Prior malaria infection treated with chloroquine- Recurrent feverssymptoms - Physical exam findings of jaundice and normal neuro exam- Low hemoglobin and peripheral blood smear showing malaria parasitesBased on the history of travel to an endemic area, prior infection, and current peripheral smear showing parasites, this is most likely a case of recurrent malaria. The key is determining why she has recurrence after being previously treated. Choice A is incorrect because antibodies play little role in malaria immunity. Choice B may occur but she did not travel recently to acquire new infection. Choice C is less likely with chloroquine. Choice D of reactivation of dormant liver stage parasites is most consistent with her presentation and history. Choice E of dissemination within macrophages is unlikely to cause recurrent symptoms.D: Reactivation of dormant liver stage 