<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:Two 19-year-old men are referred by their professor and mentor to a psychiatrist for substance abuse management. The two friends have both used different stimulants for 3 yearsDrug A and Drug B, respectively. Both use these substances cyclically. Use of Drug A usually lasts for about 12 hours. The cycle for Drug B lasts several days. A month ago, both men visited the emergency room ER due to acute intoxication. Clinical features in the emergency department included hypotension, bradycardia, sweating, chills, mydriasis, nausea, and psychomotor agitation. After a urine drug screen, the psychiatrist identifies both the drugs and informs the professor that although both Drug A and Drug B are stimulants, their mechanisms of action are different. Drug A is an alkaloid that is naturally present in the leaves of the coca plant, while it is possible to make Drug B from over-the-counter nasal decongestant products. Which of the following options best describes the mechanism of action of both drugs?? A: Drug A transiently increases the extracellular concentration of dopamine in the reward circuit, while Drug B does not., B: Drug A predominantly acts by inhibiting the reuptake of monoamine neurotransmitters dopamine, serotonin, and norepinephrine at the synapse, while Drug B does not., C: Drug A predominantly acts by increasing the release of monoamine neurotransmitters dopamine, serotonin, and norepinephrine into the synapse, while Drug B does not., D: Drug A increases serotonin activity, while Drug B does not., E: Drug A increases norepinephrine activity, while Drug B does not.,  <response>: This is a medical question asking about the mechanisms of action of two stimulant drugs, Drug A and Drug B, in two young men with substance abuse issues. Based on the information provided, Drug A is likely cocaine, which is derived from the coca plant, while Drug B is likely methamphetamine, which can be made from over-the-counter nasal decongestants. The key to answering this question is understanding the mechanisms of action of cocaine versus methamphetamine. Cocaine blocks the reuptake of dopamine, serotonin, and norepinephrine, increasing their levels in the synapse. Methamphetamine causes the release of monoamine neurotransmitters like dopamine, serotonin, and norepinephrine into the synapse and also inhibits their reuptake.So the correct answer should highlight that Drug A cocaine blocks reuptake of neurotransmitters while Drug B methamphetamine increases release and blocks reuptake of neurotransmitters.B: Drug A predominantly acts by inhibiting the reuptake of monoamine neurotransmitters dopamine, serotonin, and norepinephrine at the synapse, while Drug B does not. 