<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 57-year-old nulliparous woman comes to the physician 2 weeks after noticing a lump in her right breast. Her last mammogram was performed 4 years ago and showed no abnormalities. Menopause began 2 years ago, during which time the patient was prescribed hormone replacement therapy for severe hot flashes and vaginal dryness. Vital signs are within normal limits. Examination of the right breast shows a firm, nontender mass close to the nipple. There are no changes in the skin or nipple, and there is no palpable axillary adenopathy. The abdomen is soft and nontender; there is no organomegaly. Mammography shows a suspicious 2-cm mass adjacent to the nipple. Which of the following is the most appropriate next step in management?? A: Fine needle aspiration, B: Bone scan, C: Measurement of serum CA 153, D: Mastectomy, E: Core needle biopsyn,  <response>: This is a question about the appropriate next step in managing a 57-year-old woman with a suspicious breast mass found on mammogram. The key points from the stem are:- 57-year-old nulliparous woman - Noticed a lump in her right breast 2 weeks ago- Last mammogram 4 years ago was normal- Menopause began 2 years ago, on hormone replacement therapy- Exam shows firm, nontender mass close to the nipple of right breast- No skinnipple changes or palpable lymphadenopathy - Mammogram shows suspicious 2cm mass adjacent to nippleThe choices given are:A Fine needle aspirationB Bone scan C Measurement of serum CA 15-3 tumor markerD MastectomyE Core needle biopsyFine needle aspiration can obtain cells from the breast mass for cytologic evaluation, but has limited diagnostic accuracy. It may be reasonable as an initial step, but core needle biopsy is more definitive for diagnosis. Bone scan would not be appropriate, as there are no indications of metastatic disease at this point. Measuring a tumor marker like CA 15-3 would also not be useful yet, as an abnormal result would need tissue diagnosis first to confirm cancer.Mastectomy would be premature without a confirmed breast cancer diagnosis. Core needle biopsy can obtain a sample of the suspicious mass for histopathologic diagnosis, and is the most appropriate next step.E: Core needle biopsy 