<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 51-year-old woman with AIDS presents to her primary care physician with fatigue and weakness. She has a history of type 2 diabetes mellitus, hypertension, infectious mononucleosis, and hypercholesterolemia. She currently smokes 1 pack of cigarettes per day, drinks a glass of wine per day, and denies any illicit drug use. Her temperature is 36.7C 98.0F, blood pressure is 12674 mm Hg, pulse is 87min, and respirations are 17min. On physical examination, her pulses are bounding. The patents complexion is pale. She has an enlarged cervical lymph node, and breath sounds remain clear. Further lab and tissue diagnostic evaluation reveal and confirms Burkitts lymphoma with diffuse bulky disease. After receiving more information about her condition and treatment options, the patient agrees to start chemotherapy. Eight days after starting chemotherapy, she presents with decreased urinary output. Laboratory studies show:Creatinine 7.9 mgdLBUN 41 mgdLSerum uric acid 28 mgdLPotassium 6.9 mEqLWhich therapy is most likely to reverse the patients metabolic abnormalities?? A: Intravenous saline with mannitol with the goal of a daily urinary output above 2.5 Lday, B: Hemodialysis, C: Intravenous sodium bicarbonate with the goal of urinary pH 7.0, D: Allopurinol 300 mgday, E: Intravenous recombinant uricase enzyme rasburicase,  <response>: This is a question about managing acute kidney injury AKI in a patient undergoing chemotherapy for Burkitts lymphoma. The patient has decreased urinary output and lab values consistent with AKI, likely due to tumor lysis syndrome given the recent start of chemotherapy and high tumor burden. The correct management is to initiate hemodialysis, as this will help correct the metabolic derangements hyperkalemia, hyperuricemia, uremia and fluid overload associated with AKI. IV fluids and urinary alkalinization may help promote uric acid excretion but will not be as effective as hemodialysis at managing the current abnormalities. Allopurinol decreases future uric acid production but does not lower current serum uric acid levels. Rasburicase converts uric acid into allantoin which is more soluble, but hemodialysis is still needed to remove excess potassium and manage uremia.B: Hemodialysis 