<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 53-year-old farmer presents to the clinic for evaluation of a pigmented lesion on his arm. He states that he first noticed the lesion last year, but he believes that it has been slowly growing in size. He otherwise does not have any complaints and is generally healthy. Which of the following findings on physical exam would suggest a malignant diagnosis?? A: Different pigmentation throughout the lesion, B: Flat lesion with symmetric hyperpigmentation, C: Hyperpigmented lesion with smooth borders, D: Symmetrical ovoid lesion, E: Tenderness to palpation,  <response>: This is a question about identifying malignant features of a pigmented skin lesion in a patient. The key is looking for asymmetry, irregular borders, color variation, large diameter, and evolution over time - features that are suspicious for melanoma. Choices A and C mention color variation within the lesion, which raises suspicion for melanoma. Choice E can be eliminated, as tenderness is not a typical feature. Choices B and D describe benign-appearing symmetric lesions without concerning features.A: Different pigmentation throughout the lesion 