<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 46-day-old baby is admitted to the pediatric ward with an elevated temperature, erosive periumbilical lesion, clear discharge from the umbilicus, and failure to thrive. She is the first child of a consanguineous couple born vaginally at 38 weeks gestation in an uncomplicated pregnancy. She was discharged home from the nursery within the first week of life without signs of infection or jaundice. The umbilical cord separated at 1 month of age with an increase in temperature and periumbilical inflammation that her mother treated with an herbal decoction. The vital signs are blood pressure 7045 mm Hg, heart rate 129min, respiratory rate 26min, and temperature, 38.9C 102.0F. The babys weight is between the 10th and 5th percentiles and her length is between the 50th and 75th percentiles for her age. The physical examination shows an erosive lesion with perifocal erythema in the periumbilical region with drainage but no pus. The rest of the examination is within normal limits for the patients age. The complete blood count shows the following results:Erythrocytes 3.4 x 106mm3Hb 11 gdLTotal leukocyte countNeutrophilsLymphocyteEosinophilsMonocytesBasophils 49.200mm36133222Platelet count 229,000mm3The umbilical discharge culture shows the growth of Staphylococcus aureus. Flow cytometry is performed for suspected primary immunodeficiency. The patient is shown to be CD18-deficient. Which of the following statements best describes the patients condition?? A: The patients neutrophils fail to produce reactive oxygen species to destroy engulfed bacteria., B: The patients leukocytes cannot interact with selectins expressed on the surface of endothelial cells., C: The patients leukocytes fail to adhere to the endothelium during their migration to the site of infection., D: There is excessive secretion of IL-2 in this patient., E: The patient has impaired formation of membrane attack complex.,  <response>: This is a medical question about a 46-day-old infant with signs and symptoms suggestive of omphalitis infection of the umbilical stump, failure to thrive, and consanguineous parents. The umbilical discharge culture grew Staphylococcus aureus. Flow cytometry showed the patient to be CD18 deficient. The key findings here are:- Infant with omphalitis - Failure to thrive- Consanguineous parents - Growth of Staph aureus from umbilical discharge- CD18 deficiency on flow cytometryCD18 is part of the integrin family and is important for leukocyte adhesion and migration. Patients with CD18 deficiency typically present with delayed separation of the umbilical cord, recurrent bacterial infections, and impaired pus formation due to the inability of neutrophils to migrate to sites of infection. So the patient likely has leukocyte adhesion deficiency type 1 LAD-1, an autosomal recessive immunodeficiency caused by mutations in the CD18 gene.C: The patients leukocytes fail to adhere to the endothelium during their migration to the site of infection. 