<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 66-year-old man comes to the physician because of yellowish discoloration of his eyes and skin, abdominal discomfort, and generalized fatigue for the past 2 weeks. He has had dark urine and pale stools during this period. He has had a 10-kg 22-lb weight loss since his last visit 6 months ago. He has hypertension. He has smoked one pack of cigarettes daily for 34 years. He drinks three to four beers over the weekends. His only medication is amlodipine. His temperature is 37.3C 99.1F, pulse is 89min, respirations are 14min, and blood pressure is 11474 mm Hg. Examination shows jaundice of the sclera and skin and excoriation marks on his trunk and extremities. The lungs are clear to auscultation. The abdomen is soft and nontender. The remainder of the examination shows no abnormalities. Laboratory studies show:Hemoglobin 12 gdLLeukocyte count 5,000mm3Platelet count 400,000mm3SerumUrea nitrogen 28 mgdLCreatinine 1.2 mgdLBilirubinTotal 7.0 mgdLDirect 5.5 mgdLAlkaline phosphatase 615 ULAspartate aminotransferase AST, GOT 170 ULAlanine aminotransferase ALT, GPT 310 ULγ-Glutamyltransferase GGT 592 UL N 550 ULAn ultrasound shows extrahepatic biliary dilation. A CT scan of the abdomen shows a 2.5-cm 1-in mass in the head of the pancreas with no abdominal lymphadenopathy. The patient undergoes biliary stenting. Which of the following is the most appropriate next step in the management of this patient?? A: Stereotactic radiation therapy, B: Gastroenterostomy, C: Pancreaticoduodenectomy, D: Gemcitabine and 5-fluorouracil therapy, E: Central pancreatectomy,  <response>: This is a clinical vignette describing a 66-year-old man with jaundice, weight loss, and abnormal liver tests concerning for obstructive jaundice due to pancreatic cancer. Imaging reveals a pancreatic head mass causing biliary obstruction that has been stented. The question is asking for the most appropriate next step in management.Choices include radiation therapy, gastroenterostomy, pancreaticoduodenectomy Whipple procedure, chemotherapy, and central pancreatectomy. Since imaging reveals a likely pancreatic cancer causing biliary obstruction, the most appropriate next step would be surgical resection if the patient is a surgical candidate. Pancreaticoduodenectomy Whipple procedure is the standard surgical treatment for resectable pancreatic head cancers.C: Pancreaticoduodenectomy 