<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 17-year-old girl comes to the urgent care center after testing negative for HIV. She recently had sexual intercourse for the first time and had used a condom with her long-term boyfriend. She has no personal history of serious illness and no history of sexually transmitted infections. However, the patient is still worried about the possibility she has HIV despite the negative HIV test. She states that the package insert of the HIV test shows that of 100 patients who are found to be HIV-positive on PCR, 91 tested positive via the HIV test. Later in the day, a 23-year-old woman with a history of genitourinary chlamydia infection also comes to the urgent care center after testing negative for HIV. She states that she recently had unprotected intercourse with someone who might have HIV. If the test is conducted a second time on the 23-year-old patient, how will its performance compare to a second test conducted on the 17-year-old patient?? A: Increased sensitivity, B: Increased validity, C: Increased specificity, D: Decreased positive predictive value, E: Decreased negative predictive value,  <response>: This is a question about the performance characteristics of an HIV test when conducted on patients with different pre-test probabilities of having HIV. The key information is:- The 17-year-old has low pre-test probability of HIV based on being in a monogamous relationship, using protection, and no prior STIs. - The 23-year-old has higher pre-test probability due to unprotected sex with someone possibly HIV-positive and prior STIs.- The test has 91 sensitivity based on the package insert data.When conducted on a population with low pre-test probability, the test will have high negative predictive value. When conducted on a population with higher pre-test probability, the test will have lower negative predictive value.E: Decreased negative predictive value 