<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 49-year-old man presents to his primary care physician for leg pain. He states that when he goes for walks with his dog, he starts feeling calf pain. He either has to stop or sit down before the pain resolves. He used to be able to walk at least a mile, and now he starts feeling the pain after 8 blocks. His medical history includes hyperlipidemia and hypertension. He takes lisinopril, amlodipine, and atorvastatin, but he admits that he takes them inconsistently. His blood pressure is 16182 mmHg, pulse is 87min, and respirations are 16min. On physical exam, his skin is cool to touch and distal pulses are faint. His bilateral calves are smooth and hairless. There are no open wounds or ulcers. Dorsi- and plantarflexion of bilateral ankles are 55 in strength. Ankle-brachial indices are obtained, which are 0.8 on the left and 0.6 on the right. In addition to lifestyle modifications, which of the following is the next best step in management?? A: Angioplasty, B: Arteriography, C: Bed rest, D: Clopidogrel, E: Electromyography,  <response>: This is a question about peripheral arterial disease PAD presenting as intermittent claudication. The key findings in the stem are the patients calf pain with walking that is relieved by rest, diminished peripheral pulses, cool extremities, and abnormal ankle-brachial indices confirming PAD. The choices include both diagnostic tests like arteriography and inappropriate management options like bed rest or EMG. The best next step is medical management with antiplatelet therapy, so clopidogrel is the correct answer. Lifestyle modifications like smoking cessation and exercise are also important but clopidogrel is more urgent to reduce thrombosis risk.D: Clopidogrel 