<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 12-year-old boy is brought by his parents to the physician for a fever for the past 2 days. His temperature is 101.3F 38.5C. His medical history is significant for sickle cell disease and recurrent infections. A year ago, he underwent spleen scintigraphy with technetium-99m that revealed functional hyposplenism. Which of the following findings would be found in a peripheral blood smear from this patient?? A: Acanthocytes, B: Basophilic stippling, C: Heinz bodies, D: Howell-Jolly bodies, E: Schistocytes,  <response>: This is a clinical vignette about a 12-year-old boy with sickle cell disease who presents with fever. His history is significant for functional hyposplenism. The question asks about expected peripheral blood smear findings in this patient.The key facts are:- 12-year-old boy - Fever- History of sickle cell disease- Functional hyposplenism confirmed by spleen scintigraphySickle cell disease can cause functional hyposplenism due to repeated vaso-occlusive crises infarcting the spleen. Lack of splenic function leads to impaired clearance of abnormal red blood cells. The expected peripheral blood smear finding in splenic dysfunction is Howell-Jolly bodies. These are nuclear remnants in red blood cells that are normally removed by the spleen. Of the choices given, Howell-Jolly bodies would be most consistent with this clinical scenario. The other findings are not specifically associated with hyposplenism.D: Howell-Jolly bodies 