<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:Five days after undergoing right knee arthroplasty for osteoarthritis, a 68-year-old man has severe pain in this right knee preventing him from participating in physical therapy. On the third postoperative day when the dressing was changed, the surgical wound appeared to be intact, slightly swollen, and had a clear secretion. He has a history of diabetes, hyperlipidemia, and hypertension. Current medications include metformin, enalapril, and simvastatin. His temperature is 37.3C 99.1F, pulse is 94min, and blood pressure is 13088 mm Hg. His right knee is swollen, erythematous, and tender to palpation. There is pain on movement of the joint. The medial parapatellar skin incision appears superficially opened in its proximal and distal part with yellow-green discharge. There is blackening of the skin on both sides of the incision. Which of the following is the next best step in the management of this patient?? A: Surgical debridement, B: Nafcillin therapy, C: Removal of prostheses, D: Vacuum dressing, E: Antiseptic dressingn,  <response>: This is a patient who underwent knee arthroplasty 5 days ago and now has signs of infection including fever, erythema, swelling, pain, and purulent discharge from the incision site. The main options presented are surgical debridement, antibiotic therapy, prosthesis removal, vacuum dressing, and antiseptic dressing. Surgical debridement is the best next step because it allows drainage of infection, removal of necrotic tissue, and sampling for culture to guide antibiotic therapy. Nafcillin provides coverage for staphylococci but broader spectrum antibiotics would likely be needed given the severity of infection. Removal of the prosthesis may ultimately be needed but debridement should come first. Vacuum and antiseptic dressings may help manage the wound but do not address the underlying infection.A: Surgical debridement 