<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 1-year-old infant is brought to the emergency department by his parents because of fever and rapid breathing for the past 2 days. He had a mild seizure on the way to the emergency department and developed altered sensorium. His mother states that the patient has had recurrent respiratory infections since birth. He was delivered vaginally at term and without complications. He is up to date on his vaccines and has met all developmental milestones. His temperature is 37.0C 98.6F, pulse rate is 200min, and respirations are 50min. He is lethargic, irritable, and crying excessively. Physical examination is notable for a small head, an elongated face, broad nose, low set ears, and cleft palate. Cardiopulmonary exam is remarkable for a parasternal thrill, grade IV pansystolic murmur, and crackles over both lung bases. Laboratory studies show hypocalcemia and lymphopenia. Blood cultures are drawn and broad-spectrum antibiotics are started, and the child is admitted to the pediatric intensive care unit. The intensivist suspects a genetic abnormality and a fluorescence in situ hybridization FISH analysis is ordered which shows 22q11.2 deletion. Despite maximal therapy, the infant succumbs to his illness. The parents of the child request an autopsy. Which of the following findings is the most likely to be present on autopsy?? A: Hypertrophy of Hassalls corpuscles, B: Aplastic thymus, C: Hypercellular bone marrow, D: Absent follicles in the lymph nodes, E: Accessory spleen,  <response>: This is a clinical vignette about a 1-year-old infant with recurrent respiratory infections, fever, rapid breathing, seizure, and altered mental status. The description of his physical exam findings, lab results, and genetic testing are consistent with DiGeorge syndrome. The question asks about the most likely autopsy finding in this patient.DiGeorge syndrome is caused by a deletion in chromosome 22q11.2, which results in abnormal development of the third and fourth pharyngeal pouches. This leads to defects in the parathyroid glands, thymus, and great vessels. Therefore, the most likely autopsy finding in this patient would be an underdeveloped or absent thymus gland.Choices A, C, and E describe findings in other lymphoid organs but not the thymus specifically. Choice D may occur but would not be as direct a result of the 22q11.2 deletion as thymic aplasia or hypoplasia.B: Aplastic thymus 