<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 26-year-old man comes to the physician because of episodic palpitations for the past 2 months. He has the feeling that sometimes his heart skips a beat. His father has a history of atrial fibrillation and myocardial infarction. He has smoked one pack of cigarettes daily for 5 years. He drinks 12 beers on the weekends. His vital signs are within normal limits. Physical examination reveals a regular pulse. Cardiopulmonary examination shows no abnormalities. Serum studies, including electrolytes and creatinine, are within normal limits. An excerpt of 24h Holter monitoring is shown. Echocardiography is normal. Which of the following is the most appropriate next step in management?? A: Diltiazem therapy, B: Coronary angiography, C: Metoprolol therapy, D: Permanent pacemaker placement, E: Smoking cessation,  <response>: This is a question about a 26-year-old man with palpitations and a family history of atrial fibrillation and myocardial infarction. He has smoked 1 pack per day for 5 years and drinks 1-2 beers on weekends. Vital signs, physical exam, labs, and echocardiogram are normal. The Holter monitor shows premature atrial contractions. The key findings are the premature atrial contractions on Holter and his smoking history. Premature atrial contractions can trigger atrial fibrillation. Cigarette smoking increases risk of atrial fibrillation. Coronary angiography is not indicated given his young age and lack of cardiac symptoms. Permanent pacemaker is not indicated as there is no evidence of bradyarrhythmias. The most appropriate next step is smoking cessation to reduce his risk of developing atrial fibrillation.E: Smoking cessation 