<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 43-year-old woman comes to the physician because of a 6-week history of hoarseness and difficulty swallowing. She also has a history of lower back pain treated with ibuprofen. She is 162 cm 5 ft 4 in tall and weighs 77 kg 169 lb; BMI is 29 kgm2. Her pulse is 64min and blood pressure is 13086 mm Hg. Physical examination shows dry skin, swelling of the lower extremities, and a hard nontender anterior neck swelling that does not move with swallowing. Femoral and pedal pulses are decreased bilaterally. A biopsy of the neck swelling is most likely to show which of the following findings?? A: Atypical nuclei and concentric lamellar calcifications, B: Spindle cells and areas of focal necrosis, C: Collagen deposition and decreased number of follicles, D: Giant cells and noncaseating granulomas, E: Lymphocytic infiltrate and germinal center formation,  <response>: This is a clinical vignette describing a 43-year-old woman with a 6-week history of hoarseness, difficulty swallowing, lower back pain treated with ibuprofen, high BMI, neck swelling, dry skin, leg swelling, and decreased peripheral pulses. The key findings pointing to the diagnosis are:- Hoarseness and difficulty swallowing - suggests laryngeal or esophageal involvement- Hard, nontender anterior neck swelling that does not move with swallowing - suggests thyroid pathology- Dry skin and leg swelling - suggests hypothyroidism- Decreased peripheral pulses - suggests atherosclerosis which can be associated with hypothyroidismBased on the constellation of symptoms and signs, the most likely diagnosis is hypothyroidism leading to thyroid enlargement and compression of adjacent structures. A biopsy of the thyroid in this case would be expected to show findings consistent with hypothyroidism.C: Collagen deposition and decreased number of follicles 