<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 54-year-old man with known end-stage liver disease from alcoholic cirrhosis presents to the emergency department with decreased urinary output and swelling in his lower extremities. His disease has been complicated by ascites and hepatic encephalopathy in the past. Initial laboratory studies show a creatinine of 1.73 mgdL up from a previous value of 1.12 one month prior. There have been no new medication changes, and no recent procedures performed. A diagnostic paracentesis is performed that is negative for infection, and he is admitted to the hospital for further management and initiated on albumin. Two days later, his creatinine has risen to 2.34 and he is oliguric. Which of the following is the most definitive treatment for this patients condition?? A: Cessation of alcohol use, B: Peritoneovenous shunt, C: Transjugular intrahepatic portosystemic shunt TIPS, D: Liver transplantation, E: Hemodialysis,  <response>: This is a patient with end-stage liver disease complicated by ascites and hepatic encephalopathy who now has worsening renal function and oliguria. The key finding is that he has developed hepatorenal syndrome, which is kidney injury due to reduced renal perfusion from vasodilation and low systemic vascular resistance caused by advanced liver dysfunction. Hepatorenal syndrome is a serious complication that portends a poor prognosis without definitive treatment. Of the choices given, liver transplantation is the most definitive treatment for hepatorenal syndrome in this patient with end-stage liver disease. Cessation of alcohol use may prevent further liver injury but does not reverse existing damage. Peritoneovenous shunting and TIPS can help manage ascites but do not address the underlying liver dysfunction causing hepatorenal syndrome. Hemodialysis can temporarily replace some kidney function but does not treat the root cause.D: Liver transplantation 