<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 69-year-old diabetic woman comes to the emergency department due to right flank pain for 10 days. Her right flank pain is radiating towards her groin and is associated with fever and chills. The pain is exacerbated with hip extension. She feels fatigued and is lying on her left side with her right hip flexed. The CT guided percutaneous drainage reveals 900 ml of greenish pus. The vital signs include blood pressure 14575 mm Hg, pulse rate 96min, temperature 36.9C 98.4F, respiratory rate 16min, and the oxygen saturation is 95. The complete blood count shows the following results upon admission:CBC results Leukocytes 16,600mm3Neutrophils 80Lymphocytes 16Eosinophils 1Basophils 1Monocyte 2Hemoglobin 7.6 gdLCreatinine 0.8 mgdLBUN 15 mgdLWhich of the following processes most likely could have occurred?? A: Downregulation of regulation of cellular adhesion molecules in the endothelium, B: Diapedesis of neutrophils and chemotactic agents, C: Activation of cytosolic caspases, D: Decreased expression of selectin in the endothelium, E: Vasoconstriction,  <response>: Based on the information provided in the question stem, this is a case of a 69-year-old diabetic woman presenting with right flank pain radiating to the groin, fever, chills, fatigue, and pus drainage from the right flank. She has elevated white blood cell count with neutrophilia. This clinical presentation is most consistent with acute pyelonephritis with abscess formation. The question asks which process most likely occurred in this patient. Looking at the answer choices, choice B Diapedesis of neutrophils and chemotactic agents seems most fitting with the clinical picture. Pyelonephritis causes inflammation and infection in the kidney which leads to release of chemotactic factors and recruitment of neutrophils from circulation into infected tissue. This process is called diapedesis.Choices A, C, D, and E do not fit with the clinical scenario described. There is no information to suggest problems with regulation of cellular adhesion molecules, caspase activation, issues with selectins, or vasoconstriction.B: Diapedesis of neutrophils and chemotactic agents 