<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 1-year-old boy is brought to his pediatrician for a follow-up appointment. He was recently diagnosed with failure to thrive and developmental delay. His weight is 7 kg 15.4 lb, height is 61 cm 24 in, and head circumference is 42 cm 16.5 in. The patients father had a younger sister who suffered from mental and physical delay and died at a very young age. The patient was able to raise his head at the age of 7 months and began to sit alone only recently. He babbles, coos, and smiles to other people. On presentation, his blood pressure is 7540 mm Hg, heart rate is 147min, respiratory rate is 28min, and temperature is 36.4C 97.5F. He has a coarse face with small deep orbits, proptotic eyes, big lips, and gingival hyperplasia. His skin is pale with decreased elasticity. His lung and heart sounds are normal. Abdominal examination reveals diminished anterior abdominal wall muscle tone and hepatomegaly. Muscle tone is increased in all groups of muscles on both upper and lower extremities. The physician becomes concerned and performs testing for the suspected hereditary disease. A blood test shows increased lysosomal enzyme concentration in the serum and decreased N-acetylglucosamine-1-phosphotransferase GlcNAc phosphotransferase activity within the leukocytes. Which of the statements listed below describes the mechanism of the patients condition?? A: The patients symptoms are due to dysfunctional metabolism of sphingomyelin, which accumulates within the lysosomes., B: There is impaired hydrolysis of GM2-ganglioside, which accumulates in the cytoplasm., C: The lysosomal enzymes are secreted from the cells instead of being targeted to lysosomes because of lack of mannose phosphorylation on N-linked glycoproteins., D: Due to enzyme deficiency, glycogen is extensively accumulated within the hepatocytes., E: The symptoms result from defective glycolysis, which results in a total energy deficiency.,  <response>: This is a question about a 1-year-old boy with failure to thrive, developmental delay, coarse facial features, hepatomegaly, and increased muscle tone. He has a family history of a sibling with similar issues who died young. Lab testing shows increased lysosomal enzymes in the serum and decreased GlcNAc phosphotransferase activity in leukocytes. Based on the clinical presentation and lab findings, this patient likely has a lysosomal storage disease. The choices describe different mechanisms that could lead to lysosomal storage disease symptoms. Choice C matches the finding of decreased GlcNAc phosphotransferase activity, which is needed to add mannose residues to lysosomal enzymes so they can be targeted to lysosomes. Without this, the enzymes end up secreted outside the cell rather than inside lysosomes.Choices A, B, D, and E describe other mechanisms unrelated to the lab findings in this patient.C: The lysosomal enzymes are secreted from the cells instead of being targeted to lysosomes because of lack of mannose phosphorylation on N-linked glycoproteins. 