<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A scientist is studying the process of thymus-dependent B cell activation in humans. He observes that, after bacterial infections, the germinal centers of secondary lymphoid organs become highly metabolically active. After subsequent reinfection with the same pathogen, the organism is able to produce immunoglobulins at a much faster pace. Which of the following processes is likely taking place in the germinal centers at the beginning of an infection?? A: Development of early pro-B cells, B: Development of immature B cells, C: T cell positive selection, D: T cell negative selection, E: Affinity maturation,  <response>: This is a question about B cell activation and the development of immunological memory. The key details in the question stem are: - After initial infection, germinal centers become highly metabolically active- After reinfection with the same pathogen, immunoglobulin production is faster- The question asks about the process likely taking place in germinal centers at the beginning of infectionThis indicates the process of affinity maturation, where B cells undergo somatic hypermutation and selection to improve their affinity for the pathogen antigen. Choices A and B involve early B cell development, not in germinal centers. Choices C and D involve T cell selection, not B cells. Only choice E matches the details provided.E: Affinity maturation 