<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 42-year-old woman comes to the physician with a 6-month history of breast tenderness and menstrual irregularities. Physical examination shows no abnormalities. An ultrasound of the pelvis shows a right adnexal mass. A laparoscopic right salpingo-oophorectomy is performed. Histologic examination of the adnexal mass shows small cuboidal cells arranged in clusters surrounding a central cavity with eosinophilic secretions. These cells resemble primordial follicles. Which of the following laboratory values was most likely increased in this patient at the time of presentation?? A: Estradiol, B: Lactate dehydrogenase, C: α-fetoprotein, D: β-human chorionic gonadotropin, E: Follicle stimulating hormone,  <response>: This is a clinical vignette describing a 42-year-old woman with a 6-month history of breast tenderness, menstrual irregularities, and a right adnexal mass found on pelvic ultrasound. She underwent a laparoscopic right salpingo-oophorectomy and histology showed small cuboidal cells resembling primordial follicles, indicating this was likely an ovarian tumor. The question asks which lab value was most likely increased at initial presentation. The history of breast tenderness and menstrual irregularities indicates hormonal abnormalities. The histologic findings point towards a granulosa cell tumor, which often secretes estrogen. Therefore, the lab value most likely increased is estradiol.A: Estradiol 