<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 25-year-old woman presents into the clinic complaining of worsening malaise, hair loss, and a rash on her face. The patient states that she has been avoiding daylight because the rash becomes painful, and she has not been able to go to classes because of debilitating arthralgia in her fingers and ankles. No significant past medical history. She takes no medication. At the time of the consult, the patient has a fever of 39.0C 102.2 F. The presence of which of the following is most commonly seen on diagnostic labs in this patients most likely condition?? A: Anti-smith antibody, B: Anti-dsDNA, C: Anti-histone antibody, D: Anti-Ro antibody, E: Antinuclear antibody,  <response>: Based on the description of symptoms like malaise, hair loss, rash, arthralgia, and fever, this patient likely has systemic lupus erythematosus SLE. SLE is an autoimmune disease that can affect multiple organ systems. The presence of antinuclear antibodies ANA is a hallmark lab finding in SLE, being positive in 95 of patients. Anti-dsDNA and anti-Smith antibodies are more specific for SLE but have lower sensitivity than ANA. Anti-Ro and anti-histone antibodies can be seen in SLE but are less common.E: Antinuclear antibody 