<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 27-year-old female has a history of periodic bloody diarrhea over several years. Colonoscopy shows sigmoid colon inflammation, and the patient complains of joint pain in her knees and ankles. You suspect inflammatory bowel disease. Which of the following would suggest a diagnosis of Crohn disease:? A: Left lower quadrant pain, B: Jaundice, C: Loss of large bowel haustra, D: Mucosal and submucosal ulcerations, E: Perianal fistula,  <response>: This is a clinical vignette describing a 27-year-old female with a history of bloody diarrhea, colonoscopic findings of sigmoid inflammation, joint pain, and suspected inflammatory bowel disease. The question is asking which of the following findings would suggest a diagnosis of Crohns disease specifically.Choice A describes left lower quadrant pain which can be seen in both Crohns disease and ulcerative colitis. Choice B describes jaundice which is not a typical feature of inflammatory bowel disease. Choice C describes loss of large bowel haustra which can be seen in both Crohns and ulcerative colitis. Choice D describes mucosal and submucosal ulcerations which can occur in both diseases. Choice E describes perianal fistula formation which is more specific for Crohns disease. E: Perianal fistula 