<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 38-year-old woman, gravida 3, para 2, at 12 weeks gestation comes to her obstetrician for a prenatal visit. Screening tests in the first trimester showed a decreased level of pregnancy-associated plasma protein and an increased level of β-hCG. A genetic disorder is suspected. Which of the following results from an additional diagnostic test is most likely to confirm the diagnosis?? A: Increased nuchal translucency on ultrasound, B: Additional chromosome in placental tissue, C: Decreased estriol in maternal serum, D: Triploidy in amniotic fluid, E: Decreased inhibin A in maternal serum,  <response>: This is a question about prenatal screening and diagnosis of a genetic disorder in a pregnant woman. The key details in the question stem are:- 38-year-old woman, 12 weeks pregnant- First trimester screening showed decreased PAPP-A and increased hCG- A genetic disorder is suspected based on these screening resultsThe question asks which additional diagnostic test result would most likely confirm the diagnosis. Based on the screening results, the most likely diagnosis is Down syndrome trisomy 21, which often presents with decreased PAPP-A and increased hCG. An additional diagnostic test that could confirm Down syndrome is karyotyping or FISH analysis of placental tissue, which would show an extra chromosome 21.So the correct answer should be a test that can directly analyze the fetal chromosomes.B: Additional chromosome in placental tissue 