<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A new antihypertensive medication is studied in 3,000 Caucasian men with coronary heart disease who are over age 65. The results show benefits in terms of improved morbidity and mortality as well as a decreased rate of acute coronary events with minimal side effects. After hearing about this new medication and supporting study at a recent continuing education course, a family physician elects to prescribe this medication to a 39-year-old Hispanic female who presents with primary hypertension. After a one month trial and appropriate adjustments in the dosing, the patients blood pressure is not well controlled by this medication. Which of the following statistical concepts could explain this patients poor response to the medication?? A: Confounding, B: Selection bias, C: Effect modification, D: Generalizability, E: Observer bias,  <response>: This question is asking about why a medication that was effective in an older Caucasian male population was not effective in a younger Hispanic female patient. The study population and the patient have different demographic characteristics like age, gender, and ethnicity. These differences can lead to effect modification, where the treatment effect differs between subgroups. The lack of generalizability of the study results to other populations is the likely explanation for the poor treatment response in this specific patient.D: Generalizability 