<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 55-year-old male presents to his primary care physician complaining of right hip pain for the past eight months. He also reports progressive loss of hearing over the same time period. Radiographic imaging reveals multiple areas of expanded bony cortices and coarsened trabeculae in his right hip and skull. Laboratory analysis reveals an isolated elevation in alkaline phosphatase with normal levels of serum calcium and phosphate. Which of the following histologic findings is most likely to be seen if one of the lesions were biopsied?? A: Immature woven bone with collagen fibers arranged irregularly, B: Mature lamellar bone with collagen fibers arranged in lamellae, C: Chondroblasts and chondrocytes forming a cartilaginous matrix, D: Large pleomorphic cells with numerous atypical mitotic figures and lacey osteoid formation, E: Sheets of monotonous round blue cells,  <response>: This is a clinical vignette describing a 55-year-old male with right hip pain and hearing loss over 8 months. Imaging shows expanded bony cortices and coarsened trabeculae in the right hip and skull. Lab work shows an isolated elevation in alkaline phosphatase with normal calcium and phosphate. The clinical presentation and imaging findings are consistent with Pagets disease of bone. The elevated alkaline phosphatase also supports this diagnosis. Pagets disease is characterized by excessive bone turnover and remodeling, leading to woven bone formation. Therefore, the histologic finding most likely to be seen if one of the lesions were biopsied would be immature woven bone with irregularly arranged collagen fibers.A: Immature woven bone with collagen fibers arranged irregularly 