<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 4-year-old boy is brought to the physician for the evaluation of fatigue since he returned from visiting family in South Africa one week ago. The day after he returned, he had fever, chills, and diffuse joint pain for 3 days. His symptoms improved with acetaminophen. He was born at term and has been healthy. His immunizations are up-to-date. His temperature is 37.6C 99.68F, pulse is 100min, and blood pressure is 10060 mm Hg. Examination shows conjunctival pallor. The remainder of the examination shows no abnormalities. Laboratory studies show:Hemoglobin 10.8 gdLMean corpuscular volume 68 μm3Red cell distribution width 14 N 1315Hemoglobin A2 6 N 3.5A peripheral smear shows microcytic, hypochromic erythrocytes, some of which have a darkly stained center and peripheral rim, separated by a pale ring. Which of the following is the most appropriate next step in the management of this patient?? A: Folic acid therapy, B: Oral succimer, C: Reassurance, D: Oral pyridoxine, E: Iron supplementation,  <response>: This is a clinical vignette about a 4-year-old boy with fatigue, fever, chills, and joint pain after returning from South Africa. The key findings are conjunctival pallor, low hemoglobin, microcytic and hypochromic RBCs, and elevated hemoglobin A2 on lab tests. The peripheral smear shows some RBCs with a dark center and pale periphery, consistent with ring sideroblasts. This presentation is most consistent with thalassemia minor, likely β-thalassemia. The elevated hemoglobin A2 supports this diagnosis. The next step would be reassurance, as thalassemia minor is typically asymptomatic and does not require treatment. Iron supplementation would not be helpful, as this is not iron deficiency anemia. Chelation with succimer is used for iron overload disorders but not indicated here. Folic acid and pyridoxine may help with anemia but do not address the underlying diagnosis.C: Reassurance 