<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 65-year-old patient with a history of COPD and open-angle glaucoma in the left eye has had uncontrolled intraocular pressure IOP for the last few months. She is currently using latanoprost eye drops. Her ophthalmologist adds another eye drop to her regimen to further decrease her IOP. A week later, the patient returns because of persistent dim vision. On exam, she has a small fixed pupil in her left eye as well as a visual acuity of 2040 in her left eye compared to 2020 in her right eye. Which of the following is the mechanism of action of the medication most likely prescribed in this case?? A: Inhibiting the production of aqueous humor by the ciliary epithelium, B: Closing the trabecular mesh by relaxing the ciliary muscles, C: Opening the canal of Schlemm by contracting the ciliary muscle, D: Increasing reabsorption of aqueous humor by the ciliary epithelium, E: Increasing the permeability of sclera to aqueous humor,  <response>: This is a clinical vignette about a patient with open-angle glaucoma who has uncontrolled intraocular pressure IOP despite using latanoprost eye drops. Her ophthalmologist adds another medication which further decreases her IOP but causes side effects of a small fixed pupil and dim vision. The question asks which mechanism of action of the new medication is most likely responsible for the additional IOP lowering.Choice A involves inhibiting aqueous humor production, which is a common mechanism of IOP lowering drugs like beta blockers and carbonic anhydrase inhibitors. Choice B involves closing the trabecular meshwork, which would increase rather than decrease IOP. Choice C involves contracting the ciliary muscle to open the canal of Schlemm, which is the mechanism of action of cholinergic agonists like pilocarpine. This can cause miosis or pupil constriction.Choice D involves increasing uveoscleral outflow, which is the mechanism of action of prostaglandin analogues like latanoprost that the patient is already using. Choice E involves increasing scleral permeability, but no glaucoma medications work this way.C: Opening the canal of Schlemm by contracting the ciliary muscle 