<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 42-year-old female with a history of systemic lupus erythematous SLE has a 3-year history of daily prednisone 20 mg use. Due to long-term prednisone use, she is at increased risk for which of the following?? A: Hair loss, B: Weight loss, C: Pancreatic insufficiency, D: Systolic hypertension, E: Pathologic fractures,  <response>: This patient has a history of long-term daily prednisone use for SLE. The chronic use of corticosteroids like prednisone can lead to several side effects. Choice A of hair loss is a common side effect of prednisone. Choice B of weight loss is not a typical side effect, prednisone often causes weight gain. Choice C of pancreatic insufficiency is not a known side effect. Choice D of systolic hypertension is a potential side effect of chronic steroid use. Choice E of pathologic fractures is correct, as chronic steroid use can cause osteoporosis and increase fracture risk.E: Pathologic fractures 