<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 31-year-old female receives a kidney transplant for autosomal dominant polycystic kidney disease ADPKD. Three weeks later, the patient experiences acute, T-cell mediated rejection of the allograft and is given sirolimus. Which of the following are side effects of this medication?? A: Nephrotoxicity, hypertension, B: Pancreatitis, C: Hyperlipidemia, thrombocytopenia, D: Cytokine release syndrome, hypersensitivity reaction, E: Nephrotoxicity, gingival hyperplasia,  <response>: This is a question about the side effects of sirolimus, an immunosuppressive medication used to prevent rejection after organ transplantation. The patient has ADPKD and received a kidney transplant, then experienced acute T-cell mediated rejection and was started on sirolimus. We need to identify the side effects of sirolimus from the choices provided. Sirolimus is not typically associated with nephrotoxicity or hypertension, so we can eliminate choices A and E. Cytokine release syndrome and hypersensitivity reactions are not common side effects, so choice D is incorrect. The remaining choices, B and C, list two of the most common side effects of sirolimus - pancreatitis and hyperlipidemiathrombocytopenia. C: Hyperlipidemia, thrombocytopenia 