<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 22-year-old woman presents with a complaint of low energy levels for the past 6 months. She feels as if she has no energy to do anything and has lost interest in photography, which she was previously passionate about. Feelings of hopelessness occupy her mind and she can no longer focus at work. She says she forces herself to hang out with her friends at weekends but would rather stay home. She denies any suicidal ideation. Her past medical history is significant for bulimia nervosa, which was diagnosed when she was a teen and was controlled with cognitive behavioral therapy. In addition, she has gastroesophageal reflux, which is being treated with esomeprazole. The patient has a 10-pack-year smoking history but denies any alcohol or recreational drug use. On examination, she is afebrile and vital signs are within normal limits. Her BMI is 24 kgm2. Further physical examination is unremarkable. Which of the following aspects of this patients history is a contraindication to using bupropion as an antidepressant?? A: History of bulimia nervosa, B: Age of 22 years, C: Smoking cessation, D: BMI of 24 kgm2, E: Esomeprazole usage,  <response>: This is a clinical case of a 22-year-old woman presenting with symptoms of depression, including low energy, loss of interest, feelings of hopelessness, and difficulty focusing at work. She has a history of bulimia nervosa and gastroesophageal reflux disease GERD. The question asks about a contraindication to using bupropion as an antidepressant for this patient. To answer this, we need to consider the patients history and know that bupropion can lower the seizure threshold. Bulimia nervosa increases the risk of seizures, likely due to electrolyte abnormalities. Therefore, a history of bulimia nervosa is a contraindication to using bupropion in this patient.The other answer choices do not present contraindications to bupropion use. Her age, smoking history, BMI, and GERD treatment with esomeprazole do not preclude the use of bupropion as an antidepressant.A: History of bulimia nervosa 