<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 15-year-old boy with Down syndrome is admitted to the hospital because of a 2-week history of pallor, easy bruising, and progressive fatigue. He has a history of acute lymphoblastic leukemia that has been in remission for 2 years. Examination shows cervical and axillary lymphadenopathy. Bone marrow biopsy predominantly shows immature cells that stain positive for terminal deoxynucleotidyl transferase. A diagnosis of relapsed acute lymphoblastic leukemia is made. Treatment with a combination chemotherapeutic regimen including teniposide is initiated. The effect of this drug is best explained by which of the following mechanisms of action?? A: Inhibition of microtubule formation, B: Decrease in nucleotide synthesis, C: Increase in double-stranded DNA breaks, D: Inhibition of thymidylate synthase, E: Inhibition of topoisomerase I,  <response>: This is a question about the mechanism of action of the chemotherapy drug teniposide in the treatment of acute lymphoblastic leukemia ALL. The key information in the stem is that a 15-year-old boy with Down syndrome and relapsed ALL is being treated with a chemotherapy regimen including teniposide. We need to identify which of the answer choices describes how teniposide works to treat ALL.C: Increase in double-stranded DNA breaks 