<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:An 11-year-old African American boy is brought to your office by his parents with a 1-day history of severe left hip pain. It is too painful for him to walk without support. He took ibuprofen, which brought no relief. He has had no chills or sweats. Similar painful episodes in the past required multiple hospitalizations. He returned from a trip to Kenya with his family 2 months ago. His vaccinations are up-to-date. His temperature is 38C 100.4 F, pulse is 100min, blood pressure is 12080 mm Hg. Physical examination shows pale conjunctivae. The abdomen is soft with no organomegaly. Passive movement of the hip causes severe pain. There is tenderness on palpation, but no swelling, warmth, or erythema of the hip. His laboratory studies show a hematocrit of 25 and leukocyte count of 14 000mm3. A peripheral blood smear would most likely show which of the following?? A: Trophozoites, B: Decreased number of thrombocytes, C: Decreased number of reticulocytes, D: Howell-Jolly bodies, E: Gram-negative bacillin,  <response>: This is a clinical vignette about an 11-year-old African American boy with severe left hip pain and a history of similar episodes requiring hospitalizations. He recently returned from travel to Kenya. He has fever, tachycardia, conjunctival pallor, severe hip pain and tenderness, anemia and leukocytosis. The key findings here are the recurrent episodes of severe hip pain requiring hospitalizations, recent travel to Kenya, fever, conjunctival pallor, anemia and leukocytosis. This clinical presentation is most consistent with sickle cell disease with a vaso-occlusive crisis likely triggered by a recent infection acquired during travel. Sickle cell disease can lead to anemia and leukocytosis. A peripheral smear would show sickled RBCs, target cells, and Howell-Jolly bodies which are remnants of nuclear material in RBCs seen with splenic dysfunction from repeated sickling. Of the answer choices, Howell-Jolly bodies would be most likely seen on a peripheral smear in this patient with sickle cell disease.D: Howell-Jolly bodies 