<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 28-year-old woman comes to the physician because of a two-month history of fatigue and low-grade fevers. Over the past 4 weeks, she has had increasing shortness of breath, a productive cough, and a 5.4-kg 11.9-lb weight loss. Three months ago, the patient returned from a two-month trip to China. The patient appears thin. Her temperature is 37.9C 100.2F, pulse is 75min, and blood pressure is 12570 mm Hg. Examination shows lymphadenopathy of the anterior and posterior cervical chain. Rales are heard at the left lower lobe of the lung on auscultation. Laboratory studies show a leukocyte count of 11,300mm3 and an erythrocyte sedimentation rate of 90 mmh. An x-ray of the chest shows a patchy infiltrate in the left lower lobe and ipsilateral hilar enlargement. Microscopic examination of the sputum reveals acid-fast bacilli; polymerase chain reaction is positive. Sputum cultures are pending. After placing the patient in an airborne infection isolation room, which of the following is the most appropriate next step in management?? A: Await culture results before initiating treatment, B: Perform interferon-γ release assay, C: Obtain CT scan of the chest, D: Administer only isoniazid for 9 months, E: Administer isoniazid, rifampin, pyrazinamide, and ethambutol for 2 months, followed by isoniazid and rifampin for 4 months,  <response>: This is a clinical vignette describing a 28-year-old woman with a 2-month history of fatigue, low-grade fevers, shortness of breath, cough, weight loss, and recent travel to China. She has exam findings consistent with tuberculosis, including lymphadenopathy, lung rales, elevated inflammatory markers, and chest x-ray showing infiltrates and hilar enlargement. Acid-fast bacilli were seen on sputum microscopy and PCR was positive, confirming Mycobacterium tuberculosis infection. The question asks for the most appropriate next step in management.E: Administer isoniazid, rifampin, pyrazinamide, and ethambutol for 2 months, followed by isoniazid and rifampin for 4 months 