<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:You are called to evaluate a newborn. The patient was born yesterday to a 39-year-old mother. You observe the findings illustrated in Figures A-C. What is the most likely mechanism responsible for these findings?? A: Hypothyroidism, B: Microdeletion on chromosome 22, C: Maternal alcohol consumption during pregnancy, D: Trisomy 18, E: Trisomy 21,  <response>: This is a question about identifying the most likely cause of abnormalities seen in a newborn infant. The key findings described are low-set ears, epicanthal folds, and clenched fists. These are classic physical exam findings seen in trisomy 21, also known as Down syndrome. Trisomy 21 is caused by an extra copy of chromosome 21 and is associated with intellectual disability, characteristic facial features, and other birth defects. Hypothyroidism can cause intellectual disability but not the facial or hand findings described. A microdeletion on chromosome 22 would cause DiGeorge syndrome, which has a different pattern of defects. Maternal alcohol consumption can cause fetal alcohol syndrome, but this does not typically cause the facial or hand findings noted here. Trisomy 18 has some overlapping features with trisomy 21 but clenched fists and epicanthal folds are more specific for trisomy 21.E: Trisomy 21 