<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 54-year-old man comes to the physician for a health maintenance examination. He feels well. He is 173 cm 5 ft 8 in tall and weighs 84 kg 185 lb; BMI is 28 kgm2. His vital signs are within normal limits. Physical examination shows no abnormalities. Serum lipid studies show:Total cholesterol 280 mgdLHDL-cholesterol 30 mgdLLDL-cholesterol 195 mgdLTriglycerides 275 mgdLTreatment with atorvastatin and cholestyramine is initiated. Which of the following changes is most likely induced by both agents?? A: Increased lipoprotein lipase activity, B: Increased LDL receptor expression, C: Increased hepatic bile salt synthesis, D: Decreased hepatic de novo cholesterol synthesis, E: Increased cholesterol levels in hepatocytes,  <response>: This is a question about the mechanisms of action of two lipid-lowering medications, atorvastatin and cholestyramine. The patient has dyslipidemia characterized by high total cholesterol, low HDL, high LDL, and high triglycerides. Atorvastatin is a statin drug that inhibits HMG-CoA reductase, which is the rate-limiting enzyme in cholesterol synthesis. This results in increased LDL receptor expression and increased LDL clearance. Cholestyramine is a bile acid sequestrant that binds bile acids in the intestine, preventing their reabsorption. This leads to increased conversion of cholesterol into bile acids to replace those lost, resulting in decreased hepatic cholesterol stores.B: Increased LDL receptor expression 