<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 6-year-old boy is brought to the pediatrician by his foster father because he is concerned about the boys health. He states that at seemingly random times he will have episodes of severe difficulty breathing and wheezing. Upon questioning, the pediatrician learns that these episodes do not appear to be associated with exercise, irritants, or infection. The pediatrician suspects the child has a type of asthma that is associated with eosinophils. In this type of asthma, what is released by the eosinophils to cause bronchial epithelial damage?? A: IL-5, B: Major basic protein, C: IgM, D: IL-8, E: Interferon-gamma,  <response>: This is a clinical vignette describing a 6-year-old boy with episodic wheezing and breathing difficulty not clearly associated with common asthma triggers like exercise, irritants, or infection. The physician suspects the child may have eosinophilic asthma based on the clinical presentation. The question asks what is released by eosinophils that can cause bronchial epithelial damage. IgM is an immunoglobulin and not released by eosinophils. IL-5 stimulates eosinophil production and activation. IL-8 is a chemokine that attracts neutrophils, not eosinophils. Interferon gamma is a cytokine secreted by T cells and NK cells. Major basic protein is released by activated eosinophils and can be toxic to epithelial cells, so it is the most likely answer.B: Major basic protein 