<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 49-year-old man presents to his primary care physician complaining of multiple symptoms. He states that over the past 8 months he has noticed voice changes and difficulty swallowing. The dysphagia started with just dry foods like crackers but has progressed to include smoothies and ice cream. He works as a newspaper editor and has also noticed trouble writing with his dominant hand. He is accompanied by his wife, who complains that he snores and drools in his sleep. His medical history is significant for hypertension and a bicuspid aortic valve. He takes hydrochlorothiazide. On physical examination, there is atrophy of the right hand. The patients speech is slow. A systolic murmur at the right upper sternal border is appreciated. Tapping of the left patellar tendon causes the patients left lower extremity to forcefully kick out. Stroking of the plantar aspect of the patients left foot causes his left toes to extend upward. Which of the following therapies is most likely to slow the progression of the patients symptoms?? A: Amantadine, B: Beta interferon, C: Donepezil, D: Reserpine, E: Riluzole,  <response>: This question describes a patient with progressive symptoms of dysphagia, dysarthria, hand weakness, snoring, drooling, and signs of upper and lower motor neuron disease on exam. The key finding is upper and lower motor neuron signs, which indicate amyotrophic lateral sclerosis ALS. Riluzole is the only FDA-approved medication for ALS and has been shown to slow disease progression and extend survival in some patients. The other answer choices are medications used for Parkinsons disease, multiple sclerosis, or hypertension, which do not treat the underlying pathology in ALS.E: Riluzole 