<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 25-year-old man comes to the physician for the evaluation of recurrent episodes of nosebleeds over the past 6 months. The nosebleeds occur spontaneously and stop after 10 minutes after pinching the nose at the nostrils. He has no history of serious illness except for prolonged bleeding following wisdom teeth extraction 2 years ago. He does not smoke or drink alcohol. He takes no medications. Vital signs are within normal limits. Examination of the nose shows no abnormalities. There are several bruises on the lower extremities. The remainder of the examination shows no abnormalities. Laboratory studies show:Hemoglobin 15 gdLLeukocyte count 6,000mm3Platelet count 220,000mm3Bleeding time 9 minutesProthrombin time 13 secPartial thromboplastin time 55 secWhich of the following is the most likely diagnosis?? A: Bernard-Soulier Syndrome, B: Wiskott-Aldrich syndrome, C: Hemophilia A, D: Factor X deficiency, E: Von Willebrand disease,  <response>: Based on the information provided in the question stem, the key findings are:- 25-year-old man with recurrent nosebleeds over the past 6 months- Prolonged bleeding after wisdom teeth extraction 2 years ago - No other significant medical history- Normal vital signs and nasal exam- Bruising on lower extremities- Normal hemoglobin, leukocyte count, platelet count- Prolonged bleeding time of 9 minutes- Normal prothrombin time - Prolonged partial thromboplastin time of 55 secondsThe prolonged bleeding time and partial thromboplastin time indicate a defect in the intrinsic coagulation pathway. The lack of other hematologic abnormalities makes hemophilia A and thrombocytopenia less likely. The lack of immunodeficiency features makes Wiskott-Aldrich syndrome unlikely. Bernard-Soulier syndrome would typically have thrombocytopenia. Therefore, the most likely diagnosis is von Willebrand disease, which can cause impaired platelet plug formation and intrinsic coagulation defects.E: Von Willebrand disease 