<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 57-year-old woman comes to the physician for evaluation of a lump in the right breast that she first noticed a week ago. Biopsy of the mass confirms a diagnosis of a pleomorphic lobular carcinoma-in-situ that is estrogen receptor-positive. The patient undergoes lumpectomy, and treatment with tamoxifen is initiated. Which of the following conditions is most likely to occur as a result of tamoxifen therapy?? A: Endometrial cancer, B: Osteoporosis, C: Myelosuppression, D: Ovarian cancer, E: Cardiotoxicity,  <response>: This is a clinical case about a 57-year-old woman with estrogen receptor-positive pleomorphic lobular carcinoma-in-situ of the breast who underwent lumpectomy and was started on tamoxifen therapy. The question asks about the most likely side effect or adverse event that could occur as a result of tamoxifen therapy. Tamoxifen is a selective estrogen receptor modulator SERM used for estrogen receptor-positive breast cancers. It acts as an estrogen antagonist in the breast, but has some estrogen agonist effects in other tissues like the uterus and bones. Common side effects of tamoxifen include endometrial cancer, uterine abnormalities, osteoporosis, and thromboembolic events. Of the choices given, endometrial cancer is the most likely side effect to occur with tamoxifen therapy.A: Endometrial cancer 