<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:In a healthy patient with no renal abnormalities, several mechanisms are responsible for moving various filtered substances into and out of the tubules. Para-aminohippurate PAH is frequently used to estimate renal blood flow when maintained at low plasma concentrations. The following table illustrates the effect of changing plasma PAH concentrations on PAH excretion:Plasma PAH concentration mgdL Urinary PAH concentration mgdL0 010 6020 12030 15040 180Which of the following mechanisms best explains the decrease in PAH excretion with the increase in plasma concentration greater than 20 mgdL?? A: Saturation of PAH transport carriers, B: Increased diffusion rate of PAH, C: Decreased glomerular filtration of PAH, D: Increased flow rate of tubular contents, E: Increased rate of PAH reabsorption,  <response>: This is a question about renal physiology and the mechanisms involved in the excretion of para-aminohippurate PAH. The question provides a table showing that as plasma PAH concentration increases, urinary PAH excretion increases up to a point, but then levels off and decreases at higher plasma concentrations. The answer choices describe different mechanisms that could potentially explain this decrease in PAH excretion at higher plasma concentrations. Based on the information provided, it seems that as plasma PAH increases, more is filtered by the glomerulus up to a point, leading to increased urinary excretion. However, at higher plasma concentrations, the transporters that secrete PAH from the blood into the tubule become saturated, limiting the amount that can be excreted. This saturation of PAH transport carriers at high plasma concentrations best explains the observed decrease in urinary PAH excretion.A: Saturation of PAH transport carriers 