<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 35-year-old man presents with large tense blisters on the flexor surfaces of the upper extremities and trunk. The histologic findings show subepidermal blisters with an eosinophil-rich infiltrate. What is the most likely underlying pathology?? A: Autoantibodies to desmoglein 1, B: Autoantibodies to desmoglein 3, C: Granular deposits of immunoglobulin A IgA in the dermal papilla, D: Linear band of immunoglobulin G IgG in the epidermal basement membrane, E: Linear band of IgA in the basement membrane,  <response>: Based on the description of large tense blisters on the flexor surfaces and a subepidermal blistering with eosinophilic infiltrate on histology, the most likely diagnosis is bullous pemphigoid. This is an autoimmune blistering disease caused by autoantibodies against hemidesmosomal proteins like BP180 and BP230 in the basement membrane zone. The presence of eosinophils in the inflammatory infiltrate is characteristic of bullous pemphigoid.D: Linear band of immunoglobulin G IgG in the epidermal basement membrane 