<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:Two days following the home birth of her son, a mother brings the infant to the pediatric emergency room because of bilious vomiting. He is unable to pass meconium and his abdomen is distended. Endoscopic biopsy of the proximal colon demonstrates an absence of Meissners and Auerbachs plexi in the bowel wall. Which of the following is the most likely diagnosis?? A: Hirschsprungs disease, B: Ileocecal intussusception, C: Meckels diverticulum, D: Juvenile polyposis syndrome, E: Volvulus of the sigmoid colon,  <response>: This is a clinical vignette describing an infant with bilious vomiting, inability to pass meconium, and abdominal distension since birth. The key finding is the absence of Meissners and Auerbachs plexi on biopsy of the proximal colon. Meissners plexus is located in the submucosa and Auerbachs plexus is located between the longitudinal and circular muscle layers. The absence of these neural plexi indicates aganglionosis, which is the hallmark of Hirschsprungs disease. Hirschsprungs disease is characterized by the absence of ganglion cells in the myenteric and submucosal plexuses of the distal bowel, leading to functional obstruction. Bilious vomiting in a newborn suggests high intestinal obstruction, and the distended abdomen is consistent with obstruction. Inability to pass meconium is another classic sign of Hirschsprungs in a newborn.The other choices do not fit with the clinical vignette or explain the key biopsy finding of absent neural plexi. Therefore, Hirschsprungs disease is the most likely diagnosis.A: Hirschsprungs disease 