<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 29-year-old woman presents with skin lesions on her elbows and forearms. She notes that they first started appearing 2 months ago and have not improved. She describes the lesions as painless and rarely itchy. She denies any similar symptoms in the past, and has no other significant past medical history. Review of systems is significant for recent joint pain, conjunctivitis, and corneal dryness. The patient is afebrile and vital signs are within normal limits. Non-tender, raised, inflamed, white-silver maculopapular lesions are present. Which of the following are the most likely histopathologic findings in this patients skin biopsy?? A: Intracellular edema with detachment at basal level, B: Subepidermal blister detachment at suprabasal level, C: Cytoplasmic vacuolation, D: Basal cell hyperplasia, proliferation of subepidermal vasculature, and keratinization, E: Nuclear atypia, cellular pleomorphism, and a disorganized structure of cells from basal to apical layers of the tissue,  <response>: This is a clinical vignette describing a 29-year-old woman with skin lesions on her elbows and forearms that started 2 months ago. The lesions are described as painless, rarely itchy, raised, inflamed, white-silver maculopapular lesions. She also has a history of recent joint pain, conjunctivitis, and corneal dryness. The description of the skin lesions along with the associated symptoms of joint pain, conjunctivitis, and corneal dryness are classic for discoid lupus erythematosus DLE. DLE is a chronic skin condition that can occur in people with systemic lupus erythematosus. Histopathologic findings in DLE skin biopsies typically show:- Basal cell layer hyperplasia and proliferation of small vessels in the superficial dermis - Follicular plugging - Perivascular and periadnexal lymphocytic inflammationD: Basal cell hyperplasia, proliferation of subepidermal vasculature, and keratinization 