<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:Fifteen years ago, a physician was exposed to Mycobacterium tuberculosis during a medical mission trip to Haiti. A current CT scan of his chest reveals respiratory apical granulomas. The formation of this granuloma helped prevent the spread of the infection to other sites. Which pair of cells contributed to the walling-off of this infection?? A: TH1 cells and macrophages, B: TH2 cells and macrophages, C: TH1 cells and neutrophils, D: TH2 cells and neutrophils, E: CD8 T cells and NK cells,  <response>: This is a question about the immune response to Mycobacterium tuberculosis infection. The key details are:- The physician was exposed 15 years ago, indicating this is a chronic infection- CT scan shows apical granulomas, which are characteristic of TB infection- Granulomas help wall off the infection and prevent its spreadSo we need to identify which immune cells contribute to granuloma formation in TB infection. Granulomas consist of macrophages surrounded by lymphocytes. TH1 cells activate macrophages to contain the infection. Neutrophils and CD8 T cells are not major players in the chronic phase of TB infection.A: TH1 cells and macrophages 