<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 1-year-old girl born to a 40-year-old woman is undergoing an examination by a pediatric resident in the hospital. The pregnancy was uneventful and there were no complications during the delivery. The physical examination reveals midface hypoplasia with a flat nasal bridge and upslanting palpebral fissures. She has a small mouth and chest auscultation reveals a blowing holosystolic murmur that is heard best along the sternal border. The family history is unremarkable. A karyotype analysis is ordered because the resident suspects a numerical chromosomal disorder. Which of the following phenomena leads to the infants condition?? A: Trinucleotide repeat, B: Meiotic non-disjunction, C: Uniparental disomy, D: Genomic imprinting, E: Partial deletion,  <response>: This is a clinical vignette describing a 1-year-old girl with distinctive facial features like midface hypoplasia, flat nasal bridge, upslanting palpebral fissures, and a small mouth. She also has a heart murmur. Given the mothers advanced maternal age, the pediatric resident suspects a numerical chromosomal disorder caused by meiotic nondisjunction during gamete formation in the mother. B: Meiotic non-disjunction 