<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 5-year-old boy is brought to the physician by his parents because of a 6-week history of increased tiredness, irritability, and worsening leg pain. His parents report that he has been reluctant to walk recently because of the pain in his legs. Examination shows conjunctival pallor and diffuse petechiae. There are palpable, nontender posterior cervical and axillary lymph nodes. His hemoglobin concentration is 8.9 gdL, leukocyte count is 45,750mm3, and platelet count is 25,000mm3. A bone marrow aspiration shows numerous immature cells that stain positive for CD10, CD19, and terminal deoxynucleotidyl transferase TdT. Which of the following translocations is associated with a favorable prognosis for this patients condition?? A: t12;21, B: t15;17, C: t8;14, D: t14;18, E: t9;22,  <response>: Based on the patients symptoms of fatigue, irritability, leg pain, conjunctival pallor, petechiae, enlarged lymph nodes, low hemoglobin, high leukocyte count, low platelet count, and bone marrow findings of immature B cells positive for CD10, CD19, and TdT, this patient likely has B-cell acute lymphoblastic leukemia ALL. The question asks about a translocation associated with a favorable prognosis. t12;21, also known as the ETV6-RUNX1 fusion, is the most common genetic abnormality in pediatric B-cell ALL and is associated with a good prognosis. t15;17 is associated with acute promyelocytic leukemia. t8;14 is associated with Burkitt lymphoma.t14;18 is associated with follicular lymphoma. t9;22 is the Philadelphia chromosome associated with chronic myelogenous leukemia.A: t12;21 