<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 31-year-old G3P0020 presents to her physician for a prenatal visit at 12 weeks gestation. She does not smoke cigarettes and stopped drinking alcohol once she was diagnosed with pregnancy at 10 weeks gestation. An ultrasound examination showed the following:Ultrasound finding Measured Normal value age-specifiedHeart rate 148min 137150minCrown-rump length 44 mm 4552 mmNasal bone visualized visualizedNuchal translucency 3.3 mm 2.5 mmWhich of the following statements regarding the presented patient is correct?? A: Pathology other than Down syndrome should be suspected because of the presence of a nasal bone., B: To increase the diagnostic accuracy of this result, the levels of free beta-hCG and pregnancy-associated plasma protein A PAPP-A should be determined., C: The observed ultrasound image is caused by the problems with the embryonic kidneys., D: At this gestational age, nuchal translucency has low diagnostic value., E: To increase the diagnostic accuracy of this result, the levels of serum alpha-fetoprotein, hCG, and unconjugated estriol should be determined.,  <response>: This is a question about interpreting the results of an ultrasound examination during pregnancy. The key findings are that the fetal heart rate, crown-rump length, and nasal bone are normal for 12 weeks gestation. However, the nuchal translucency measurement of 3.3 mm is above the normal cutoff of 2.5 mm at this gestational age. An increased nuchal translucency can indicate an increased risk of Down syndrome or other chromosomal abnormalities. To confirm this finding, checking levels of free beta-hCG and PAPP-A would be recommended as these are screening markers used in combination with nuchal translucency to calculate Down syndrome risk. The other answer choices are incorrect interpretations of the ultrasound findings.B: To increase the diagnostic accuracy of this result, the levels of free beta-hCG and pregnancy-associated plasma protein A PAPP-A should be determined. 