<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 22-year-old man is rushed to the emergency room with constant, severe right lower abdominal pain that started 7 hours ago in the periumbilical region and later shifted to the right lower quadrant with a gradual increase in intensity. The patients blood pressure is 11080 mm Hg, the heart rate is 76min, the respiratory rate is 17min, and the temperature is 37.5C 99.5F. The physical examination shows tenderness, muscle guarding, and rebound over the right lower quadrant of the abdomen. Abdominal sonography shows a dilated appendix with a periappendiceal fluid collection. He is diagnosed with acute appendicitis and undergoes a laparoscopic appendectomy. The histopathologic examination of the removed appendix is shown in the image. Which of the following substances is responsible for attracting the marked cells to the inflamed tissue?? A: IL-7, B: IL-8, C: CCL-11, D: CXCL-9, E: IL-10,  <response>: This is a clinical vignette describing a typical presentation of acute appendicitis in a young adult male. The history, physical exam findings, imaging, and histopathology are all consistent with acute appendicitis. The question asks which substance is responsible for attracting the marked inflammatory cells to the inflamed appendix tissue. Based on the description, this is likely referring to neutrophils, which are one of the first responders in acute inflammation. The choices given are different cytokines and chemokines. IL-8, also known as CXCL8, is a chemokine that acts as a potent chemoattractant and activator of neutrophils. The other choices do not have significant neutrophil chemoattractant properties.B: IL-8 