<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 12-year-old girl is brought to an oncologist, as she was recently diagnosed with a rare form of cancer. Cytogenetic studies reveal that the tumor is responsive to vinblastine, which is a cell-cycle specific anticancer agent. It acts on the M phase of the cell cycle and inhibits the growth of cells. Which of the following statements best describes the regulation of the cell cycle?? A: Cyclin-dependent activation of CDK1 CDC2 takes place upon the entry of a cell into M phase of the cell cycle., B: EGF from a blood clot stimulates the growth and proliferation of cells in the healing process., C: The G0 phase is the checkpoint before G1., D: Inhibitors of DNA synthesis act in the M phase of the cell cycle., E: Replication of the genome occurs in the M phase of the cell cycle.,  <response>: This is a question about the cell cycle and how vinblastine, an anticancer drug, acts on it. The key points in the question stem are:- 12-year-old girl diagnosed with rare cancer - Tumor responsive to vinblastine, which inhibits cell growth by acting on the M phase- Looking for which statement best describes regulation of the cell cycleGoing through the choices:A Correct - Activation of CDK1 and cyclin does occur upon entry into M phase. This is part of the regulation of the cell cycle.B Incorrect - EGF and blood clot healing unrelated to regulation of cell cycle. C Incorrect - G0 is not a checkpoint before G1, it is a resting phase.D Incorrect - Inhibitors of DNA synthesis act in S phase, not M phase. E Incorrect - DNA replication occurs in S phase, not M phase.A: Cyclin-dependent activation of CDK1 CDC2 takes place upon the entry of a cell into M phase of the cell cycle. 