<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 3-year-old girl is brought to the physician by her parents for complaints of breast development and pubic hair growth for the past 6 months. She has no significant birth or medical history. The temperature is 37.0C 98.6F, the pulse is 88min, and the respirations are 20min. Physical examination shows enlarged breasts at Tanner stage 3 and pubic hair at stage 2. Height and weight are in the normal range. On GnRH stimulation testing, a luteinizing hormone LH response of 5 IUL is detected. What is the most appropriate next step in diagnosis?? A: Repeat the GnRH stimulation test to see the LH response, B: Use a GnRH test to see the LH:FSH ratio, C: Use a leuprolide test to see the estradiol levels, D: Use a leuprolide test to see the testosterone levels, E: Use a GnRH test to see the FSH levels,  <response>: This is a question about precocious puberty in a 3-year-old girl. She is showing signs of early breast and pubic hair development. GnRH stimulation testing showed a low LH response, which indicates central precocious puberty. The next step would be to confirm central precocious puberty by checking for pubertal levels of sex hormones using a GnRH agonist like leuprolide. Choice A is incorrect because repeating the GnRH test is unlikely to provide additional useful information. Choice B is incorrect because the LH:FSH ratio is not helpful for diagnosis in this case. Choice C is correct because a leuprolide stimulation test can help confirm central precocious puberty by demonstrating pubertal levels of estradiol. Choice D is incorrect because checking testosterone levels is not useful for diagnosing central precocious puberty in a girl. Choice E is incorrect because checking FSH levels is not the most appropriate next step. The key is to check sex hormone levels.C: Use a leuprolide test to see the estradiol levels 