<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 5-year-old boy presents for a regularly scheduled check-up. The child is wheelchair bound due to lower extremity paralysis and suffers from urinary incontinence. At birth, it was noted that the child had lower limbs of disproportionately small size in relation to the rest of his body. Radiograph imaging at birth also revealed several abnormalities in the spine, pelvis, and lower limbs. Complete history and physical performed on the childs birth mother during her pregnancy would likely have revealed which of the following?? A: Maternal hyperthyroidsim, B: Uncontrolled maternal diabetes mellitus, C: Maternal use of tetracyclines, D: Maternal use of lithium, E: Maternal use of nicotine,  <response>: This is a clinical vignette describing a 5-year-old boy with lower extremity paralysis, urinary incontinence, and abnormalities of the spine, pelvis, and lower limbs noted at birth. The question is asking what maternal history during pregnancy would likely explain these findings in the child.Choice A of maternal hyperthyroidism can cause low birth weight but not the skeletal abnormalities described. Choice B of uncontrolled maternal diabetes mellitus can cause caudal regression syndrome, which includes lower extremity and spinal abnormalities. This is likely the correct answer.Choice C of maternal tetracycline use can cause discoloration of teeth in the child but not these skeletal abnormalities.Choice D of maternal lithium use can cause Ebstein anomaly in the child but not these skeletal abnormalities. Choice E of maternal nicotine use can cause low birth weight but not these skeletal abnormalities.B: Uncontrolled maternal diabetes mellitus 