<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 65-year-old male with diffuse large B cell lymphoma is treated with a chemotherapy regimen including 6-mercaptopurine. Administration of which of the following agents would increase this patients risk for mercaptopurine toxicity?? A: Leucovorin, B: Dexrazoxane, C: Mesna, D: Allopurinol, E: Amifostine,  <response>: This is a question about drug interactions with 6-mercaptopurine, a chemotherapy medication. It is asking which additional agent would increase the risk of toxicity when given with 6-mercaptopurine. Leucovorin is used to enhance the efficacy of some chemotherapy drugs, but does not interact with 6-mercaptopurine. Dexrazoxane, mesna, and amifostine are cardioprotectants or cytoprotectants that also do not interact. Allopurinol decreases metabolism of 6-mercaptopurine, leading to increased levels and toxicity.D: Allopurinol 