<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 17-year-old girl comes to the physician because of a 12-hour history of profuse watery diarrhea with flecks of mucus that started shortly after she returned from a trip to South America. She has not had any fever or nausea. Pulse is 104min and blood pressure is 11065 mm Hg. Physical examination shows dry mucous membranes and decreased skin turgor. Stool culture shows gram-negative, comma-shaped, flagellated bacilli. Therapy with oral rehydration solution is initiated. Which of the following is the most likely mechanism of this patients diarrhea?? A: Reduced ability of water absorption in the colon due to rapid intestinal transit, B: Fluid and electrolyte loss due to inflammation of luminal surface epithelium, C: Luminal chloride hypersecretion due to overactivation of adenylate cyclase, D: Impaired intestinal motility due to degeneration of autonomic nerves, E: Excessive water excretion due to osmotically active solutes in the lumen,  <response>: This is a clinical case of a 17-year-old girl with acute watery diarrhea after returning from a trip to South America. The description of profuse watery diarrhea with flecks of mucus suggests an infectious diarrhea. The finding of gram-negative, comma-shaped, flagellated bacilli on stool culture is consistent with Vibrio cholerae infection. The key finding in the question stem is the presence of severe watery diarrhea without fever or inflammation, which points to a non-inflammatory secretory diarrhea. The patient is also showing early signs of dehydration clinically. This presentation is classic for cholera, which causes diarrhea due to the cholera toxin produced by V. cholerae. This toxin activates adenylate cyclase, causing increased chloride and water secretion into the intestinal lumen.C: Luminal chloride hypersecretion due to overactivation of adenylate cyclase 