<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 45-year-old woman presents to the office because of shortness of breath and chest tightness on exertion which she noticed for the past 2 months. She was diagnosed with asthma 1 month ago but says that the asthma medication has not improved her breathing. She does not smoke and works as a hotel manager. Examination shows mildly jaundiced conjunctivae, several spider nevi on her upper torso, and a barrel-chested appearance. A chest X-ray is obtained. Which of the following is the most likely diagnosis?? A: Alpha 1-antitrypsin deficiency, B: Bilateral pneumothorax, C: Kartagener syndrome, D: Pneumomediastinum, E: Pulmonary hypertension,  <response>: Based on the information provided in the question stem, the key findings are:- 45-year-old woman with shortness of breath and chest tightness on exertion for 2 months- Diagnosed with asthma 1 month ago, but asthma medication has not helped - No smoking history- Physical exam shows jaundiced conjunctivae, spider nevi on torso, barrel-chested appearance- Chest X-ray obtainedThe jaundiced conjunctivae, spider nevi, and barrel-chested appearance point towards a diagnosis of liver disease. The lack of improvement with asthma medications makes asthma less likely. The chest X-ray was obtained to evaluate the shortness of breath and chest tightness. Of the choices given, alpha-1 antitrypsin deficiency can lead to both lung and liver disease. The other choices do not explain both the lung and liver findings.A: Alpha 1-antitrypsin deficiency 