<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 56-year-old man comes to the physician because of a painless blistering rash on his hands, forearms, and face for 2 weeks. The rash is not itchy and seems to get worse in the sunlight. He has also noticed that his urine is darker than usual. His aunt and sister have a history of similar skin lesions. Examination of the skin shows multiple fluid-filled blisters and oozing erosions on the forearms, dorsal side of both hands, and forehead. There are areas of hyperpigmented scarring and patches of bald skin along the sides of the blisters. Which of the following is the most appropriate pharmacotherapy to treat this patients condition?? A: Hemin, B: Prednisone, C: Fexofenadine, D: Acyclovir, E: Hydroxychloroquine,  <response>: This patient has a blistering rash on sun-exposed areas of his hands, forearms, and face that is not itchy but gets worse with sun exposure. He also has dark urine and a family history of similar lesions. The clinical description is most consistent with porphyria cutanea tarda, which causes blistering skin lesions and dark urine due to excess porphyrins. The most appropriate treatment is hydroxychloroquine. Hydroxychloroquine can decrease porphyrin production and is commonly used to treat porphyria cutanea tarda. Prednisone may be used to treat blistering but does not treat the underlying porphyrin excess. Hemin treats acute intermittent porphyria but not porphyria cutanea tarda. Fexofenadine is an antihistamine and would not treat the blistering. Acyclovir treats herpes infections, which this is not.E: Hydroxychloroquine 