<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 55-year-old man presents with severe fatigue and fever. His past medical history is significant for a recent history of mononucleosis from which he fully recovered 8 weeks ago. On physical examination, the patient seems pale. A chest radiograph shows multiple enlarged mediastinal lymph nodes. A biopsy of one of the enlarged mediastinal lymph nodes is performed and shows the presence of multinucleated cells with an owl-eye appearance in a hypocellular background. This patients most likely condition is very aggressive and associated with a very poor prognosis. Which of the following is the most likely diagnosis in this patient?? A: Lymphocyte-depleted lymphoma, B: Diffuse large B cell lymphoma, C: Follicular lymphoma, D: Extranodal marginal zone lymphoma, E: Nodular lymphocyte-predominant lymphoma,  <response>: This is a clinical vignette describing a 55-year-old man with severe fatigue, fever, pale appearance, enlarged mediastinal lymph nodes, and biopsy results showing multinucleated cells with an owl-eye appearance. The question asks to identify the most likely diagnosis given that it is very aggressive with a poor prognosis. The history of recent mononucleosis and enlarged mediastinal lymph nodes point towards a lymphoproliferative disorder. The biopsy results showing multinucleated owl-eye cells indicate Reed-Sternberg cells, which are characteristic of Hodgkin lymphoma. The description that this condition is very aggressive with poor prognosis fits with Hodgkin lymphoma.A: Lymphocyte-depleted lymphoma 