<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 24-year-old man presents with a history of intermittent fever for the last 2 days. He says his episodes of fever are accompanied by shaking and chills. He mentions that his father has been recently recovered from chloroquine-resistant P. falciparum malaria, which was treated successfully with quinine. On physical examination, his temperature is 38.9C 102F, pulse rate is 110min, blood pressure is 11680 mm Hg, and respiratory rate is 18min. Examination of his abdomen reveals splenomegaly. His blood sample is sent for the examination of the peripheral smear, which confirms the diagnosis of Plasmodium falciparum malaria. The patient is placed on treatment with oral quinine. After 5 days, the patient returns with improved symptoms of malaria but with complaints of a headache, tinnitus, nausea, and dizziness. The patient mentions that he has been taking a drug for the last 3 months to control his dyspepsia symptoms. Which of the following drugs is most likely to have caused the above-mentioned symptoms in this patient?? A: Sucralfate, B: Famotidine, C: Cimetidine, D: Ranitidine, E: Pantoprazole,  <response>: This is a clinical vignette about a 24-year-old man with malaria who develops side effects after being treated with quinine. The key details are that he has P. falciparum malaria treated with quinine, and subsequently develops headache, tinnitus, nausea and dizziness. He has also been taking a dyspepsia medication for 3 months. The question asks which of the listed drugs is most likely causing his side effects. Since quinine is known to cause cinchonism with symptoms of headache, tinnitus, nausea and dizziness, the dyspepsia medication he has been taking is likely interacting with the quinine metabolism to cause these side effects. Of the choices given, cimetidine is an H2 blocker used for dyspepsia that can inhibit cytochrome P450 metabolism and lead to increased quinine levels and toxicity. The other drugs listed are less likely to interact with quinine in this manner.C: Cimetidine 