<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:An 8-month-old boy is brought to the physician by his parents for gradually increasing loss of neck control and inability to roll over for the past 2 months. During this time, he has had multiple episodes of unresponsiveness with a blank stare and fluttering of the eyelids. His parents state that he sometimes does not turn when called but gets startled by loud noises. He does not maintain eye contact. He was able to roll over from front to back at 5 months of age and has not yet begun to sit or crawl. His parents are of Ashkenazi Jewish descent. Neurological examination shows generalized hypotonia. Deep tendon reflexes are 3 bilaterally. Plantar reflex shows extensor response bilaterally. Fundoscopy shows bright red macular spots bilaterally. The remainder of the examination shows no abnormalities. Which of the following is the most likely cause of this patients symptoms?? A: Sphingomyelinase deficiency, B: ATP-binding cassette transporter mutation, C: β-glucocerebrosidase deficiency, D: α-galactosidase A deficiency, E: β-hexosaminidase A deficiencyn,  <response>: This is a clinical vignette describing an 8-month-old boy with gradually progressive loss of neck control, inability to roll over, episodes of unresponsiveness with eye fluttering, lack of eye contact, and inability to turn to sound. He previously achieved milestones but has regressed. His parents are Ashkenazi Jewish. Exam shows hypotonia, hyperreflexia, extensor plantar responses, and macular cherry red spots. The history and exam findings are classic for Tay-Sachs disease, a lysosomal storage disease caused by deficiency of hexosaminidase A enzyme activity leading to accumulation of GM2 gangliosides. It is particularly prevalent among Ashkenazi Jews. The macular cherry red spots and neurologic regression in an infant are characteristic. Of the choices given, option E - β-hexosaminidase A deficiency - is consistent with Tay-Sachs disease. The other options do not fit with the clinical presentation.E: β-hexosaminidase A deficiency 