<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:Please refer to the summary above to answer this questionWhich of the following is most appropriate to confirm the diagnosis in this patient?Patient informationAge: 62 yearsGender: F, self-identifiedEthnicity: unspecifiedSite of care: officeHistoryReason for VisitChief Concern: My cough is getting worse.History of Present Illness:12-month history of episodic cough and dyspnea; episodes last multiple weeks and have improved with antibioticscough is usually productive of large amounts of yellow sputum; in the past 2 days, it has been productive of cupfuls of yellow-green sputumhas occasionally noticed streaks of blood in the sputumhas not had fever, chills, or chest painPast Medical History:type 2 diabetes mellituskidney transplantation 3 years ago for diabetic nephropathyhyperlipidemiaosteoporosisSocial History:does not smoke, drink alcohol, or use illicit drugsMedications:mycophenolate mofetil, prednisone, metformin, atorvastatin, alendronateAllergies:no known drug allergiesPhysical ExaminationTemp Pulse Resp. BP O2 Sat Ht Wt BMI37.6C99.7F80min 18min 13886 mm Hg 97165 cm5 ft 5 in58 kg128 lb21 kgm2Appearance: mildly uncomfortable, sitting on the examination tableNeck: no jugular venous distentionPulmonary: cough productive of yellow-green sputum; mildly diminished lung sounds over all lung fields; bilateral expiratory wheezes, rhonchi, and crackles are heardCardiac: normal S1 and S2; no murmurs, rubs, or gallopsAbdominal: soft; nontender; a well-healed left lower abdominal scar is present at the site of kidney transplantation; normal bowel soundsExtremities: digital clubbing; no joint erythema, edema, or warmth; dorsalis pedis and radial pulses intactSkin: no rashesNeurologic: alert and oriented; cranial nerves grossly intact; no focal neurologic deficits? A: Bronchoalveolar lavage, B: Sweat chloride test, C: Mycobacterial sputum culture, D: High-resolution CT scan of the chest, E: Pulmonary function tests,  <response>: Based on the information provided in the patient summary, this 62 year old female has a 12 month history of episodic cough and dyspnea with copious sputum production. She has a history of diabetes, kidney transplant, and other comorbidities. On exam, she has digital clubbing, wheezes, rhonchi, and crackles on lung exam. This clinical presentation is most consistent with bronchiectasis or some other chronic lung infection. The next step would be to confirm this diagnosis and evaluate the extent of lung involvement. Choice A for bronchoalveolar lavage could obtain samples for culture but is invasive. Choice B for sweat chloride test is used to evaluate for cystic fibrosis, which is less likely. Choice C for mycobacterial culture could evaluate for atypical infections like TB, but standard cultures should be done first. Choice D for HRCT chest is the least invasive and best way to evaluate the extent of anatomical lung changes of bronchiectasis. Choice E for pulmonary function tests may show airflow limitation but will not confirm the diagnosis.D: High-resolution CT scan of the chest 