<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 22-year-old male presents to the physician with a 9-year history of recurring acne on his face. He has tried a number of over-the-counter face wash, gels, and supplements over the past few years with temporary relief but no significant lasting effects. The acne has gotten worse over time and now he is especially concerned about his appearance. A physical examination reveals numerous nodulocystic lesions over the face and neck. Scarring is present interspersed between the pustules. There are some lesions on the shoulders and upper back as well. Which of the following is the most appropriate treatment option for this patient at this time?? A: Oral erythromycin, B: Oral doxycycline, C: Oral isotretinoin, D: Topical isotretinoin, E: Topical salicylic acid,  <response>: This is a clinical vignette about a 22-year-old male with a 9-year history of severe, nodulocystic acne that has been refractory to over-the-counter treatments. The key findings are:- Long duration of disease 9 years - Severe, nodulocystic lesions on face, neck, shoulders and back- Presence of scarring between lesions- Failed over-the-counter treatmentsThis presentation is most consistent with severe, recalcitrant nodulocystic acne. The presence of scarring and failed previous treatments indicates that systemic therapy is needed. Oral isotretinoin is the treatment of choice for severe, recalcitrant nodulocystic acne and the only medication that addresses all major factors implicated in acne pathogenesis. The other options provided are insufficient or inappropriate for this degree of severity.C: Oral isotretinoin 