<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 2-year-old boy is brought to a pediatrician for recurrent respiratory infections. The parents explain that their child has gotten sick every month since 2 months of age. The boy had multiple upper respiratory infections and has been treated for pneumonia twice. He coughs frequently, and a trial of salbutamol has not helped much. The parents also mention that the child has bulky, irregular stools. The boy was started late on his vaccinations as his parents were in Asia on missionary work when he was born, but his vaccinations are now up to date. The patients brother and sister are both healthy and have no medical concerns. The boys delivery was unremarkable. A sweat chloride test is positive. Genetic testing shows the absence of the typical deletion in the implicated gene, but the gene length appears to be shortened by one base pair. Which mutation could account for this finding?? A: Frameshift, B: Insertion, C: Missense, D: Nonsense, E: Silent,  <response>: This is a clinical vignette about a 2-year-old boy with recurrent respiratory infections, chronic cough, and bulky stools. The key findings are positive sweat chloride test and genetic testing showing a one base pair deletion in the CFTR gene. The choices describe different types of genetic mutations. A frameshift mutation involves deletion or insertion of one or more base pairs, leading to a shift in the reading frame and often a premature stop codon. This would be consistent with the one base pair deletion described in the vignette.A: Frameshift 