<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 32-year-old man with a history of alcohol binge drinking and polysubstance use is found down in his hotel room with bottles of alcohol, oxycodone, alprazolam, amphetamine-dextroamphetamine, and tadalafil. When EMS arrives, he appears comatose with pinpoint pupils and oxygen saturation of 80 on room air. He is intubated at the scene and airlifted to the nearest intensive care unit. Body temperature is 95 degrees F 35 degrees C. Creatine phosphokinase is 12,000 UL. MRI of the brain demonstrates extensive infarcts consistent with acute hypoxic ischemic injury. Which of the following is the likely culprit for his overdose?? A: Alcohol, B: Opioids, C: Benzodiazepines, D: Amphetamines, E: Phosphodiesterase-5 PDE-5 inhibitors,  <response>: This is a question about identifying the likely cause of an overdose in a patient with a history of polysubstance abuse who is found unconscious. The key findings are pinpoint pupils, hypoxia, hypothermia, elevated CPK, and brain infarcts on MRI indicating hypoxic ischemic injury. Pinpoint pupils indicate opioid overdose as the likely cause. Opioids cause pupillary miosis. Hypothermia, elevated CPK, and hypoxic brain injury can all result from respiratory depression and hypoxia due to opioid overdose.While the patient has access to alcohol, benzodiazepines, amphetamines, and PDE5 inhibitors, the pinpoint pupils point specifically to opioids as the likely culprit.B: Opioids 