<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 57-year-old male with diabetes mellitus type II presents for a routine check-up. His blood glucose levels have been inconsistently controlled with medications and diet since his diagnosis 3 years ago. At this current visit, urinalysis demonstrates albumin levels of 250 mgday. All prior urinalyses have shown albumin levels below 20 mgday. At this point in the progression of the patients disease, which of the following is the most likely finding seen on kidney biopsy?? A: Normal kidney biopsy, no pathological finding is evident at this time, B: Glomerular hypertrophy with slight glomerular basement membrane thickening, C: Glomerular basement membrane thickening and mesangial expansion, D: Kimmelstiel-Wilson nodules and tubulointerstitial fibrosis, E: Significant global glomerulosclerosis,  <response>: This is a question about diabetic nephropathy in a patient with longstanding poorly controlled type 2 diabetes mellitus. The key finding in the question is the new onset of albuminuria, indicating the patient now has diabetic kidney disease. The progression of diabetic kidney disease begins with hyperfiltration and hypertrophy of the glomeruli, followed by thickening of the glomerular basement membranes and mesangial expansion. With prolonged disease, Kimmelstiel-Wilson nodules nodular glomerulosclerosis develop along with tubulointerstitial fibrosis. End stage disease is characterized by global glomerulosclerosis. In this patient with new onset albuminuria, the most likely kidney biopsy finding would be glomerular basement membrane thickening and mesangial expansion.C: Glomerular basement membrane thickening and mesangial expansion 