<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 32-year-old G1P0 woman undergoes her 2nd-trimester ultrasound in a community hospital. During her prenatal care, she was found to have mild anemia, low levels of folate, and serum alpha-fetoprotein levels greater than 2 multiples of the median MoM on 2 separate occasions. Her 1st-trimester ultrasound was significant for the absence of the intracranial lucency, no visualization of the cisterna magna, and posterior shift of the brain stem. These 2nd-trimester ultrasound reports reveal the widening of the lumbosacral spine ossification centers and the presence of a sac in proximity to the lumbosacral defect. Which of the following statements best describes the congenital defect in the fetus?? A: Abnormal development of the caudal eminence, B: Persistence of the anterior accessory neurenteric canal ANC, C: Failure of the rostral neuropore to close, D: Failure of the caudal neuropore to close, E: Failure of mesenchymal cells to form a neural rod,  <response>: This is a question about identifying a congenital defect based on findings from prenatal ultrasounds and lab tests. The key findings are:- Mild anemia and low folate levels in the mother - Elevated maternal serum alpha-fetoprotein on two occasions- Absence of intracranial lucency and cisterna magna, and posterior shift of brain stem on 1st trimester ultrasound - Widening of lumbosacral spine and sac near lumbosacral defect on 2nd trimester ultrasoundThese findings point to a neural tube defect, specifically failure of the caudal neuropore lower end to close properly. The elevated maternal AFP, absence of intracranial findings, and lumbosacral findings all support this. Choices A and B do not fit with the given findings. Choices C and E may cause more cranialcephalic defects. Therefore, choice D of Failure of the caudal neuropore to close is most likely.D: Failure of the caudal neuropore to close 