<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 58-year-old woman with a history of nephrolithiasis presents with fever and acute-onset right flank pain. The patient says that 2 days ago she developed sudden-onset right flank pain and nausea which has progressively worsened. She describes the pain as severe, colicky, localized to the right flank, and radiating to the groin. This morning she woke with a fever and foul-smelling urine. She has no significant past medical history. Vital signs are temperature 40.0C 104.0F, blood pressure 11070 mm Hg, pulse 92min, and respiratory rate 21min. Physical examination shows severe right costovertebral angle tenderness. Her laboratory findings are significant for the following:WBC 12,500mm3RBC 4.20 x 106mm3Hematocrit 41.5Hemoglobin 14.0 gdLPlatelet count 225,000mm3Urinalysis:Color Dark yellowClarity Clarity TurbidpH 5.9Specific gravity 1.026Glucose NoneKetones NoneNitrites PositiveLeukocyte esterase PositiveBilirubin NegativeUrobilirubin 0.6 mgdLProtein TraceRBC 325hpfWBC 8,200hpfBacteria ManyA non-contrast CT of the abdomen and pelvis shows an obstructing 7-mm diameter stone lodged at the ureteropelvic junction. There is also evidence of hydronephrosis of the right kidney. Which of the following is the best course of treatment for this patient?? A: Discharge home with oral antibiotics, B: Administer hydrochlorothiazide, C: Admit to hospital for IV antibiotics, D: Administer potassium citrate, E: Admit to hospital for percutaneous nephrostomy and IV antibiotics,  <response>: Based on the patients history of nephrolithiasis kidney stones and the acute presentation of fever, flank pain, and foul-smelling urine, this is likely a case of acute pyelonephritis kidney infection caused by an obstructing kidney stone. The CT scan confirms the presence of a 7mm obstructing stone at the ureteropelvic junction causing hydronephrosis swelling of the kidney due to obstruction. The main priorities are relieving the obstruction to allow drainageflow of urine, controlling infection, and managing pain. Oral antibiotics alone would not be adequate to treat a severe kidney infection with an obstructing stone. Hydrochlorothiazide and potassium citrate may help prevent recurrent kidney stones long-term but do not address the acute issues. The best option is E hospital admission for percutaneous nephrostomy to relieve the obstruction and allow urinary drainage along with IV antibiotics to treat the infection. This addresses the main issues in this acute presentation.E: Admit to hospital for percutaneous nephrostomy and IV antibiotics 