<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 59-year-old man comes to the emergency department because of progressive abdominal swelling and shortness of breath for 1 week. He drinks 12 to 13 alcoholic beverages daily. He appears emaciated. Examination shows pallor, jaundice, hepatomegaly, gynecomastia, and a protuberant abdomen with a fluid wave and shifting dullness. Periodic monitoring of which of the following markers is most appropriate for this patient?? A: S-100 protein, B: Alpha-fetoprotein, C: Carcinoembryonic antigen, D: Cancer antigen 19-9, E: Beta-human chorionic gonadotropin,  <response>: This is a clinical vignette describing a patient with a history of heavy alcohol use presenting with symptoms and signs of liver disease and ascites. The question is asking which tumor marker would be most appropriate to monitor periodically in this patient.Based on the description, this patient most likely has alcoholic cirrhosis leading to liver failure and portal hypertension causing the ascites. The emaciation and gynecomastia point towards malnutrition and altered metabolism from liver disease. The most concerning complication of cirrhosis is hepatocellular carcinoma HCC. Of the tumor markers listed, alpha-fetoprotein is the one most commonly used to screen for and monitor HCC in patients with cirrhosis. The other markers listed are not routinely monitored in cirrhotic patients.B: Alpha-fetoprotein 