<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 29-year-old woman presents to the emergency department with joint pain and a notable rash. She has had joint pain for the past 12 months but noticed the rash recently as well as generalized malaise. She states her joint pain is symmetric, in her upper extremities, and is worse in the morning. Her temperature is 97.6F 36.4C, blood pressure is 11174 mmHg, pulse is 83min, respirations are 14min, and oxygen saturation is 98 on room air. Laboratory studies are ordered as seen below.Hemoglobin: 10 gdLHematocrit: 30Leukocyte count: 6,800mm3 with normal differentialPlatelet count: 207,000mm3Serum:Na: 140 mEqLCl-: 101 mEqLK: 4.9 mEqLHCO3-: 21 mEqLBUN: 30 mgdLGlucose: 120 mgdLCreatinine: 1.8 mgdLThe patient is ultimately admitted to the hospital. Which of the following is the most appropriate test to monitor her disease progression?? A: Anti-CCP, B: Anti-dsDNA, C: Anti-nuclear antibody, D: Anti-topoisomerase, E: Rheumatoid factor,  <response>: Based on the description of symmetric joint pain worse in the morning, notable rash, and laboratory findings of anemia, leukopenia, thrombocytopenia, and elevated creatinine, this patient likely has systemic lupus erythematosus SLE. The anti-dsDNA antibody is most specific for diagnosing SLE and monitoring disease activity and progression. Anti-CCP is associated with rheumatoid arthritis rather than SLE. Rheumatoid factor can be positive in SLE but does not correlate well with disease activity. Anti-nuclear antibody has low specificity. Anti-topoisomerase Anti-Scl70 is associated with systemic sclerosis, not SLE.B: Anti-dsDNA 