<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 45-year-old African American male presents to his primary care physician complaining of difficulty swallowing that was initially limited to solids but has now progressed to liquids. Biopsy of the esophagus reveals dysplastic cells, but does not show evidence of glands or increased mucin. Which of the following patient behaviors most contributed to his condition?? A: Obesity, B: Smoking, C: Drinking extremely hot beverages, D: Gastroesophageal reflux disease, E: Radiation exposure in the past 6 months,  <response>: This patient is a 45-year-old African American male with dysphagia difficulty swallowing that has progressed from solids to liquids. Biopsy showed dysplastic cells in the esophagus without evidence of increased mucin production, which suggests squamous cell carcinoma rather than adenocarcinoma. The question asks which patient behavior most likely contributed to this esophageal cancer. Obesity is a risk factor for adenocarcinoma, not squamous cell carcinoma. Drinking extremely hot beverages and gastroesophageal reflux disease GERD can cause chronic irritation and inflammation that may lead to Barretts esophagus and adenocarcinoma. Recent radiation exposure can cause esophagitis but is unlikely to be the sole cause of squamous cell carcinoma in just 6 months. Smoking is the leading risk factor for squamous cell carcinoma of the esophagus. Therefore, smoking is the patient behavior that likely contributed most to his condition.B: Smoking 