<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 35-year-old male presents to his physician with the complaint of fatigue and weakness for six months. His physician orders a CBC which demonstrates anemia and thrombocytopenia. During the subsequent work up, a bone marrow biopsy is performed which ultimately leads to the diagnosis of acute promyelocytic leukemia. Which of the following translocations and fusion genes would be present in this patient?? A: t8;14 - BCRAbl1, B: t9;22 - BCRAbl1, C: t15;17 - PMLRARalpha, D: t14;18 - PMLRARalpha, E: t9;22 - PMLRARalpha,  <response>: This is a question about identifying the characteristic genetic abnormality associated with acute promyelocytic leukemia APL. The question stem describes a patient with clinical and laboratory findings consistent with APL. The choices list various translocations and fusion genes seen in different types of leukemia. To answer this, we need to recall that the hallmark genetic abnormality of APL is the t15;17 translocation which results in the PMLRARalpha fusion gene.C: t15;17 - PMLRARalpha 