<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A woman with coronary artery disease is starting to go for a walk. As she begins, her heart rate accelerates from a resting pulse of 60 bpm until it reaches a rate of 120 bpm, at which point she begins to feel a tightening in her chest. She stops walking to rest and the tightening resolves. This has been happening to her consistently for the last 6 months. Which of the following is a true statement?? A: Increasing the heart rate increases the amount of time spent during each cardiac cycle, B: Increasing the heart rate decreases the relative amount of time spent during diastole, C: Perfusion of the myocardium takes place primarily during systole, D: Perfusion of the myocardium takes place equally throughout the cardiac cycle, E: This patients chest pain is indicative of transmural ischemia,  <response>: This is a question about the physiology of coronary artery disease and angina. The key points are:- The patient has coronary artery disease, which limits blood flow to the heart muscle. - When she walks, her heart rate increases, increasing the demand for oxygen.- She experiences angina chest tightening when the heart rate reaches 120 bpm.- Angina indicates that blood flow is not meeting the increased demand, resulting in myocardial ischemia.B: Increasing the heart rate decreases the relative amount of time spent during diastole 