<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 43-year-old man presents with the complaint of pain in the small joints of his left hand. The pain is intermittent and cramping in nature in his 2nd and 3rd metacarpophalangeal MCP joints. It has progressively worsened over the past few weeks. He also reports that he has felt thirsty more often and has urinated more frequently over the past few weeks. He denies any pain during micturition. His stools are pale in color. He also reports that his skin appears to be darker than usual even though he has not been outdoors much over the past few weeks. Physical exam is significant for tenderness in the 2nd and 3rd MCPs of both hands as well as tenderness in the right upper quadrant of his abdomen. Lab results show:Aspartate aminotransferase AST 450 ULAlanine aminotransferase ALT 350 ULSerum ferritin 460 ngmLDeficiency of which of the following is the most likely cause of his symptoms?? A: Transferrin, B: Pyridoxine, C: Hepcidin, D: Ceruloplasmin, E: α1-antitrypsin,  <response>: This is a clinical vignette describing a 43-year-old man with pain and swelling in the small joints of his hands, increased thirst and urination, pale stools, dark skin, and tenderness in the right upper quadrant of the abdomen. Lab results show elevated AST, ALT, and serum ferritin. The key findings pointing to the diagnosis are:- Joint pain and swelling - suggests inflammatory arthritis- Increased thirst and urination - suggests diabetes insipidus- Pale stools - suggests anemiairon deficiency- Dark skin - suggests hemochromatosisiron overload- RUQ tenderness - suggests liver involvement- Elevated ASTALT - indicates liver injury- Elevated ferritin - indicates iron overloadGiven the constellation of joint pain, liver dysfunction, iron overload, and skinstool changes, the most likely diagnosis is hemochromatosis due to deficiency of the iron regulatory hormone hepcidin. Lack of hepcidin leads to uncontrolled intestinal iron absorption and iron deposition in tissues.C: Hepcidin 