<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 16-year-old boy is brought to the emergency department after losing consciousness. He had no preceding chest pain or palpitations. His father has cataracts and had frontal balding in his twenties but has no history of cardiac disease. His paternal grandfather also had early-onset balding. His pulse is 43min. Physical examination shows frontal hair loss, temporal muscle wasting, and testicular atrophy. Neurologic examination shows bilateral foot drop and weakness of the intrinsic hand muscles. An ECG shows bradycardia with third-degree atrioventricular block. The severity of this patients symptoms compared to that of his father is most likely due to which of the following genetic properties?? A: Pleiotropy, B: Loss of heterozygosity, C: Codominance, D: Penetrance, E: Anticipation,  <response>: This is a question about genetic properties that can explain differences in disease severity between family members. The key information is that the 16-year-old boy has more severe symptoms compared to his father, even though they both have signs of the same genetic condition. The grandfather also had early balding, suggesting this is an inherited disorder. The options describe different genetic principles that could potentially explain the difference in severity. Pleiotropy refers to a single gene affecting multiple phenotypic traits. Loss of heterozygosity and codominance relate to gene dosage effects. Penetrance refers to the proportion of individuals with a disease genotype who exhibit clinical symptoms. Anticipation refers to an increase in severity or earlier age of onset in successive generations, which fits the pattern described in this family.E: Anticipation 