<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:An investigator is studying the interaction between epithelial cells and calcium ion concentration. When the calcium ion concentration available to a sample of epithelial tissue is decreased, an increased gap between adjacent epithelial cells is seen on electron microscopy. This observed decrease in cell adhesion is most likely due to an effect on which of the following proteins?? A: Claudin, B: Cadherin, C: Actin, D: Cytokeratin, E: Integrin,  <response>: This question is asking about the effect of decreased calcium ion concentration on cell adhesion between epithelial cells. Calcium ions play an important role in cell adhesion by regulating cadherin proteins. Cadherins are calcium-dependent transmembrane proteins that mediate cell-cell adhesion. When calcium ion concentration decreases, the cadherin proteins are not able to function properly, leading to decreased cell adhesion and increased gaps between epithelial cells. B: Cadherin 