<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 66-year-old man presents to the emergency department for shortness of breath for the last 2 hours. Despite his diagnosis of heart failure 2 years ago, he has refused to make any diet changes. He takes aspirin and carvedilol but is poorly compliant. His vitals signs are pulse of 135min, respirations 30min, and a blood pressure of 15080 mm Hg. The patient is visibly distressed and unable to lie down. He is taking shallow breaths and auscultation reveals bilateral crackles in the chest. Jugular venous distension is seen. Pitting edema is present in the lower limbs. A chest X-ray shows prominent interstitial markings bilaterally with alveolar infiltrates. Which of the following is the mechanism of action of the drug that can relieve his ongoing symptoms?? A: Acting on the β-adrenergic receptors to increase cardiac contractility, B: By holding water within the tubule, leading to osmotic diuresis, C: Blocking the Na-K-2Cl- cotransporter in the thick ascending limb of the loop of Henle, D: Blocking the angiotensin II receptors, leading to vasodilation, E: Blocking the NaCl channels in the distal tubule of the nephron,  <response>: This is a clinical vignette about a 66-year-old man with a history of heart failure presenting with acute decompensated heart failure. The question is asking about the mechanism of action of a drug that can help relieve his symptoms. Based on the description, this patient has signs of fluid overload such as shortness of breath, crackles on auscultation, jugular venous distension, and pitting edema. He likely needs a diuretic to help remove excess fluid. Choices A and D refer to medications that improve cardiac contractility and cause vasodilation, which do not directly address the fluid overload. Choice B refers to a medication that causes water retention, which is the opposite of what this patient needs. Choice C refers to a loop diuretic like furosemide which blocks the NKCC transporter in the thick ascending limb, preventing reabsorption of sodium and chloride and leading to diuresis. This would help relieve the fluid overload.Choice E refers to a distal tubule diuretic like thiazide which would also cause diuresis, but is less potent in acute decompensated heart failure.C: Blocking the Na-K-2Cl- cotransporter in the thick ascending limb of the loop of Henle 