<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 16-year-old male is brought to the clinic by his mother for the complaints of fever, nonproductive cough, fatigue, lack of appetite, and sore throat for the past 2 months. Several other students at his high school have had similar symptoms. Physical exam shows a whitish membrane in his oropharynx, bilateral enlarged cervical lymphadenopathy, and mild splenomegaly. Which of the following tests is most likely to diagnose his condition.? A: Throat culture, B: Chest X-ray, C: Urine culture, D: Enzyme-linked immunosorbent assay, E: Monospot test,  <response>: Based on the information provided in the question stem, the patient is a 16-year-old male with symptoms of prolonged fever, cough, fatigue, loss of appetite, and sore throat. The description of whitish membrane in the throat, enlarged lymph nodes in the neck, and enlarged spleen point towards an infectious mononucleosis diagnosis. The Epstein-Barr virus EBV commonly causes infectious mononucleosis. The monospot or heterophile antibody test detects antibodies produced by the immune system against EBV. This is the most accurate test for diagnosing acute EBV infection. Throat culture would identify bacteria causing pharyngitis. Chest X-ray may show nonspecific findings. Urine culture is unrelated. ELISA may detect EBV antibodies but is less suitable for acute diagnosis compared to the monospot test.E: Monospot test 