<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 58-year-old man presents to his physician with breathlessness on exertion for the last 2 years. He mentions that initially, he used to become breathless upon climbing 2 flights of stairs, but now he becomes breathless after walking a couple of blocks. He has no known medical condition except obesity most recent BMI of 36 kgm2; he has been obese for the last 10 years. There is no history of substance abuse. His temperature is 36.9C 98.4F, the pulse is 90min, the blood pressure is 13088 mm Hg, and the respirations are 20min. Auscultation of the chest reveals a loud pulmonic component of the second heart sound. Auscultation over the lung fields does not reveal any specific abnormality. His chest radiogram shows enlargement of the central pulmonary arteries, attenuation of the peripheral pulmonary vessels, and oligemic lung fields. In addition to measures for weight reduction, which of the following medications is most likely to decrease breathlessness in this patient?? A: Ranolazine, B: Riociguat, C: Rivaroxaban, D: Roflumilast, E: Rolapitant,  <response>: This is a clinical vignette describing a 58-year-old obese man with exertional dyspnea that has progressed over 2 years. The key findings are obesity, loud P2 heart sound, enlarged central pulmonary arteries, attenuated peripheral pulmonary vessels, and oligemic lung fields on chest x-ray. These findings are consistent with a diagnosis of obesity hypoventilation syndrome leading to pulmonary hypertension. The question asks about medication options to treat his dyspnea, in addition to weight loss measures.B: Riociguat 