<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 35-year-old woman comes into the primary care office as a new patient with gradually worsening arthritis and reduced grip strength, primarily involving the base of her fingers, wrists, and ankles. She reports feeling slow after getting out of bed in the morning. After further questioning, she notes fatigue, low-grade fever, and feeling down. Her medical history is significant for a deep venous thrombosis, hypertension, preeclampsia, diabetes mellitus type I, and acute lymphoblastic leukemia as a child. She denies any smoking history, drinks a glass of wine each day, and endorses a past history of marijuana use but denies any current illicit drug use. Her vital signs include: temperature 36.7C 98.0F, blood pressure 12674 mm Hg, heart rate 87min, and respiratory rate 15min. On physical examination, you note symmetric joint swelling of the metacarpophalangeal and wrist joints. Radiographs of the hands demonstrate corresponding moderate, symmetric joint space narrowing, erosions, and adjacent bony decalcification. Of the following options, which is the mechanism of her reaction?? A: Type Ianaphylactic hypersensitivity reaction, B: Type IIcytotoxic hypersensitivity reaction, C: Type IIIimmune complex-mediated hypersensitivity reaction, D: Type IVcell-mediated delayed hypersensitivity reaction, E: Type III and IVmixed immune complex and cell-mediated hypersensitivity reactions,  <response>: This is a clinical vignette describing a 35-year-old woman with gradually worsening arthritis, reduced grip strength, morning stiffness, fatigue, low-grade fever, and depression. She has a history of deep venous thrombosis, hypertension, preeclampsia, type 1 diabetes mellitus, and childhood acute lymphoblastic leukemia. On exam, she has symmetric swelling and radiographic changes in her hands consistent with inflammatory arthritis. The question asks about the mechanism of her reaction. Based on the clinical presentation of inflammatory symmetric polyarthritis, the leading possibilities are rheumatoid arthritis or another immune complex-mediated process. Type III hypersensitivity reactions involve immune complex deposition and complement activation, causing inflammation. The other answer choices do not fit with the presentation.C: Type IIIimmune complex-mediated hypersensitivity reaction 