<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 34-year-old woman comes to the physician because of a 6-week history of fever and productive cough with blood-tinged sputum. She has also had a 4-kg 8.8-lb weight loss during the same time period. Examination shows enlarged cervical lymph nodes. An x-ray of the chest shows a 2.5-cm pulmonary nodule in the right upper lobe. A biopsy specimen of the lung nodule shows caseating granulomas with surrounding multinucleated giant cells. Which of the following is the most likely underlying cause of this patients pulmonary nodule?? A: IgE-mediated mast cell activation, B: Delayed T cell-mediated reaction, C: Antibody-mediated cytotoxic reaction, D: Combined type IIIIV hypersensitivity reaction, E: Immune complex depositionn,  <response>: Based on the description, this patient has a pulmonary nodule along with systemic symptoms like fever, weight loss and lymphadenopathy. The biopsy shows caseating granulomas with multinucleated giant cells, which is characteristic of tuberculosis infection. Tuberculosis is caused by cell-mediated delayed type hypersensitivity reaction to Mycobacterium tuberculosis. So this seems to be a case of delayed type IV hypersensitivity reaction causing the pulmonary nodule.B: Delayed T cell-mediated reaction 