<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 7-year-old boy presents with difficulty swallowing, diarrhea, itching, and weakness. He also complains of episodes of headaches, sweating, and palpitations, which are accompanied by fear and tend to end with micturition. His mother is concerned about the strange nodules on his lips and eyelids. The boys younger brother had similar nodules and died at 10 years of age of unknown causes. The patients vital signs are as follows: blood pressure 13080 mm Hg, heart rate 107min, respiratory rate 14min, and temperature 36.9C 98.4F. The child is tall, thin, has disproportionately long arms and legs, and increased thoracic spine kyphosis. There are multiple yellow-white, sessile, painless nodules on the patients lips, and buccal and eyelid mucosa. There is a painless lump in the area of the left thyroid lobe and enlargement of the posterior cervical lymph nodes on the left side. What is the most probable embryonic origin of the cells in the lump?? A: First pharyngeal groove, B: First pharyngeal pouch, C: Lateral plate mesoderm, D: Neurogenic placodes, E: Neural crest cells,  <response>: This is a clinical vignette describing a 7-year-old boy with multiple symptoms suggestive of a genetic disorder affecting development. The key findings are difficulty swallowing, diarrhea, itching, weakness, episodes of headachessweatingpalpitations, strange nodules on lips and eyelids, long limbs, increased kyphosis, and a painless lump in the thyroid area. Based on the constellation of symptoms and physical exam findings, this patient likely has Marfan syndrome. Marfan syndrome is an autosomal dominant genetic disorder caused by mutations in the FBN1 gene encoding fibrillin-1. It affects connective tissue and can cause issues in the skeletal, ocular, cardiovascular, and other organ systems. The lump in the thyroid area along with the other features suggests the cells originated from the neural crest. During embryonic development, neural crest cells migrate and differentiate into many cell types including bone, cartilage, connective tissue, pigment cells, and parts of the peripheral nervous system. Dysregulation of neural crest development is implicated in Marfan syndrome.Of the answer choices, neural crest cells is most consistent with Marfan syndrome as the underlying diagnosis.E: Neural crest cells 