<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 28-year-old gravida 2 para 1 is receiving care from her obstetrician at 28 weeks. She states that she has been having suprapubic pain and urinary frequency for the past week. Her past medical history is significant for dermatomyositis for which she takes prednisone every day. She does not smoke cigarettes or drinks alcohol. Her vital signs are within normal limits. Physical examination of the patient is within normal limits. A urine sample from the patient shows 100,000 CFU of Escherichia coli. Urinalysis results are provided as follows:Leukocyte esterase positiveWBC 50-100 cellsHPFNitrite positiveRBC 2 cellsHPFEpithelial cells 2 cellsHPFUrine pH 5.2Which of the following is the best pharmacotherapy for this patients condition?? A: Trimethoprim-sulfamethoxazole, B: Nitrofurantoin, C: Tetracycline, D: Cephalexin, E: Amoxicillin,  <response>: This is a patient with a urinary tract infection UTI based on the symptoms of suprapubic pain, urinary frequency, and urine culture showing 100,000 CFUmL E. coli. She is pregnant at 28 weeks gestation. The urinalysis shows evidence of infection with leukocyte esterase, nitrites, and WBCs. The main considerations for antibiotic choice in pregnant women with UTI are safety for the fetus, effectiveness against common uropathogens like E. coli, and avoiding antibiotics with increased risk of adverse effects. Tetracyclines like tetracycline are contraindicated in pregnancy due to effects on fetal bone and tooth development. Cephalosporins like cephalexin are generally avoided in late pregnancy due to theoretical risk of kernicterus in the newborn. Amoxicillin is not recommended as first-line for UTI due to rising resistance rates. Nitrofurantoin is considered safe in pregnancy and is a first-line agent for cystitis. Trimethoprim-sulfamethoxazole is also considered safe in pregnancy but avoided in some patients with folate deficiency. Based on the information provided, nitrofurantoin would be the best choice.B: Nitrofurantoin 