<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A family who recently moved from Nebraska to Texas visits the pediatrician. They have a 3-year-old child that had been developing normally before this change in location. The child became lethargic, fatigued, pale, and constipated 3 months after moving to the new house. Also, the blood smear of the patient demonstrates the finding of sideroblasts. Analyze the scheme presented below. Which of the following enzymes labeled as no. 1 is impaired in this patient and causing his symptoms?? A: Ribonuclease, B: Ferrochelatase, C: ALA oxidase, D: Uroporphyrinogen decarboxylase, E: Uroporphyrin 1,  <response>: This is a question about a 3-year-old child who recently moved from Nebraska to Texas and developed symptoms of lethargy, fatigue, paleness, constipation, and sideroblasts seen on blood smear. The key findings here are the move from Nebraska to Texas, the development of nonspecific symptoms, and the presence of sideroblasts on blood smear. Sideroblasts indicate a problem with heme synthesis, specifically with incorporating iron into protoporphyrin IX to make heme. This narrows down the possible enzyme defects to those involved in heme synthesis.The scheme shows the heme synthesis pathway. Based on the information provided, the most likely defective enzyme is ferrochelatase, which is responsible for inserting iron into protoporphyrin IX to make heme. A defect in this enzyme would lead to buildup of protoporphyrin IX and decreased heme production, consistent with the patients symptoms.The other enzymes can be ruled out: ribonuclease is not involved in heme synthesis, ALA oxidase and uroporphyrinogen decarboxylase defects would not lead to sideroblasts, and uroporphyrin I is a porphyrin intermediate not an enzyme.B: Ferrochelatase 