<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 45-year-old man presents with a chief complaint of pain in the great toe. He has a history of gout, which is under control. He was diagnosed with diabetes 5 years ago and is currently taking metformin. He was recently diagnosed with hypertension and was placed on a hypertensive drug. He is a non-smoker and does not abuse alcohol. The family history is significant for ischemic heart disease in his father. His current blood pressure is 13684 mm Hg and the pulse is 78min. The physical examination did not reveal any abnormalities. He uses over-the-counter multivitamin supplements. Which of the following drugs could have resulted in these symptoms?? A: Angiotensin II receptor blockers ARBs, B: Thiazide diuretics, C: Calcium channel blockers CCBs, D: Angiotensin-converting enzyme ACE inhibitors, E: Beta-blockers,  <response>: This is a clinical vignette about a 45-year-old man with a history of gout, diabetes, and hypertension presenting with pain in his great toe. The key details are his medical history, current medications, vital signs, and lack of abnormalities on physical exam. His current medications include metformin for diabetes and a recent antihypertensive medication. The question asks which medication could be causing his current symptoms.To answer this, I need to consider which antihypertensive medications can cause pain in the great toe as a side effect. The patients other medical conditions and medications are unlikely to be directly causing his current symptoms. I can systematically go through each answer choice and determine if that medication class could plausibly be causing his symptoms.B: Thiazide diuretics 