<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 47-year-old woman comes to the physician for a 2-month history of fatigue, intermittent left-sided flank pain, and diffuse extremity pain. She was treated for a prolactinoma 5 years ago and has had recurrent antral and duodenal peptic ulcers despite medical therapy. Her only medication is omeprazole. Physical examination shows a moderately distended abdomen that is diffusely tender to palpation. There is mild left-sided costovertebral angle tenderness. Serum studies show a calcium of 12 mgdL, phosphorus of 2 mgdL, and parathyroid hormone level of 826 pgmL. An ultrasound of the abdomen shows multiple kidney stones in the left ureteropelvic junction. This patient is most likely to have which of the following protein abnormalities?? A: Inactivation of RET proto-oncogene, B: Altered merlin protein expression, C: Altered menin protein, D: Mutation of VHL tumor suppressor, E: Mutation in C-Kit protein,  <response>: This is a clinical vignette describing a 47-year-old woman with a history of prolactinoma presenting with fatigue, flank pain, extremity pain, abdominal distension and tenderness. Lab tests show high calcium, low phosphorus and high PTH levels. Imaging shows kidney stones. The key findings here are hypercalcemia, hypophosphatemia, high PTH and history of prolactinoma. This indicates primary hyperparathyroidism, likely due to a parathyroid adenoma. The choices describe various genetic mutations associated with tumors. The correct answer would be a mutation that can cause parathyroid adenomas and primary hyperparathyroidism.C: Altered menin protein 