<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 42-year-old man who is employed as a construction worker presents to his primary care physician with complaints of moderate headaches and profuse sweating. He reports the need to carry up to 3 additional shirt changes to work because they drench quickly even with tasks of low physical exertion. His coworkers have commented about his changing glove and boot sizes, which have increased at least 4 times since he joined the company 10 years ago. Physical examination is unremarkable except for blood pressure of 16095 mm Hg, hyperhidrosis, noticeably large pores, hypertrichosis, widely spaced teeth, and prognathism. Which of the following best explains the patients clinical manifestations?? A: Increased serum metanephrines, B: Increased serum insulin-like growth factor 1 IGF-1, C: Increased serum cortisol, D: Increased thyroid-stimulating hormone, E: Increased serum testosterone,  <response>: This patient has symptoms of excessive sweating, increased shoe and glove size, coarse facial features, and high blood pressure. This clinical presentation is most consistent with acromegaly, which is caused by excess growth hormone production, usually from a pituitary adenoma. The excessive growth hormone leads to the enlargement of extremities, coarsening of facial features, hyperhidrosis, and hypertension. The lab abnormality that would confirm acromegaly is an elevated insulin-like growth factor 1 IGF-1 level. Cortisol, metanephrines, TSH, and testosterone would not explain this patients symptoms.B: Increased serum insulin-like growth factor 1 IGF-1 