<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 57-year-old man is brought to the physician for worsening mental status over the past 2 months. His wife reports he was initially experiencing lapses in memory and over the past 3 weeks he has begun having difficulties performing activities of daily living. Yesterday, he became lost heading to the post office down the street. He has hypertension treated with lisinopril and hydrochlorothiazide. Vital signs are within normal limits. He is alert but verbally uncommunicative. Muscle strength is normal. Reflexes are 2 in bilateral upper and lower extremities. He has diffuse involuntary muscle jerking that can be provoked by loud noises. Mental status examination shows a blunt affect. A complete blood count and serum concentrations of glucose, creatine, and electrolytes are within the reference range. Which of the following is the most likely diagnosis?? A: Alzheimers disease, B: Parkinsons disease, C: Huntingtons disease, D: Creutzfeldt-Jakob disease, E: Normal pressure hydrocephalus,  <response>: Based on the information provided in the question stem, the most relevant details are: - 57-year-old man with worsening mental status over 2 months- Initial memory lapses, now having difficulty with activities of daily living - Became lost going to a familiar location - Has hypertension - Alert but verbally uncommunicative, normal strength, hyperreflexia - Involuntary muscle jerking provoked by loud noises - Blunted affect on mental status exam- Normal CBC, glucose, creatinine, and electrolytesThis presentation is most consistent with Creutzfeldt-Jakob disease CJD, a rapidly progressive neurodegenerative prion disease. The early memory and functional decline, with later motor findings like myoclonus and hyperreflexia point to CJD. The normal lab tests help rule out other potential causes like electrolyte abnormalities, infection, or hydrocephalus. Alzheimers, Parkinsons, and Huntingtons diseases would have a more insidious onset. Normal pressure hydrocephalus was unlikely given the normal mental status exam.D: Creutzfeldt-Jakob disease 