<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:Two hours after undergoing allogeneic kidney transplantation for polycystic kidney disease, a 14-year-old girl has lower abdominal pain. Examination shows tenderness to palpation in the area the donor kidney was placed. Ultrasound of the donor kidney shows diffuse tissue edema. Serum creatinine begins to increase and dialysis is initiated. Which of the following is the most likely cause of this patients symptoms?? A: T-lymphocyte activation by donor HLA peptides, B: Proliferation of donor T lymphocytes, C: Preformed antibodies against class I HLA molecules, D: Irreversible intimal fibrosis and obstruction of vessels, E: Immune complex deposition in donor tissue,  <response>: This is a question about complications following kidney transplantation. The stem describes a 14-year-old girl who underwent allogeneic non-self kidney transplantation and now has lower abdominal pain and ultrasound findings of edema in the transplanted kidney. Her serum creatinine is rising, indicating declining kidney function. The choices describe different immune-mediated complications that can occur after transplantation:A T-lymphocyte activation against foreign HLA peptides can lead to rejection.B Proliferation of donor T cells could cause graft versus host disease. C Preformed antibodies against HLA molecules could cause hyperacute rejection.D Intimal fibrosis of vessels could be chronic rejection. E Immune complex deposition could cause inflammation and dysfunction.Given the acute timeframe of 2 hours after transplant and ultrasound findings of edema, options C and E involving antibodies or immune complexes seem most likely. Between these, option C of preformed antibodies against HLA molecules stands out as the most probable cause of immediate, acute rejection and dysfunction.C: Preformed antibodies against class I HLA molecules 