<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 3-year-old boy is brought to the pediatrician by his parents because of excessive growth and a large tongue. His past medical-social history reveals that he is a product of non-consanguineous marriage to a 20-year-old primigravida. He was born at full term with a birth weight of 3.8 kg 8.4 lb and length of 52 cm 20.5 in. His temperature is 37.0oC 98.6F, pulse is 90min, and respirations are 22min. Physical examination shows a mass coming out from his umbilicus and his head circumference is below average compared with children his age. On systemic examination, hepatomegaly is present. Asymptomatic hypoglycemia 36 mgdL is also detected, for which dextrose infusion is given. Which of the following is the most likely underlying mechanism that best explains the pathogenesis of this condition?? A: Mutation in tumor suppressor gene on the long arm of chromosome 11, B: Mutation in tumor suppressor gene on the short arm of chromosome 11, C: Mutation in tumor suppressor gene on the long arm of chromosome 22, D: Nondisjunction of chromosome 21, E: Mutation in tumor suppressor gene on the long arm of chromosome 17,  <response>: This is a clinical vignette describing a 3-year-old boy with signs and symptoms suggestive of a genetic disorder, including excessive growth, large tongue, umbilical hernia, low head circumference, hepatomegaly, and hypoglycemia. The question asks to identify the most likely underlying genetic mechanism that explains these findings.Based on the clinical features described, the most likely diagnosis is Beckwith-Wiedemann syndrome. This is a rare overgrowth disorder caused by abnormalities in imprinted genes on chromosome 11p15.5. The key features pointing to this diagnosis are macrosomia, macroglossia, umbilical hernia, and hypoglycemia. The answer choices describe mutations in tumor suppressor genes on chromosomes 11, 22, and 17. However, Beckwith-Wiedemann syndrome is caused by dysregulation of imprinted growth regulatory genes, not tumor suppressor genes. The only chromosome mentioned that is relevant is chromosome 11.Of the choices given, a mutation on the long arm of chromosome 11 best fits with the clinical diagnosis of Beckwith-Wiedemann syndrome.B: Mutation in tumor suppressor gene on the short arm of chromosome 11 