<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 22-year-old man comes to the physician for the evaluation of a skin rash over both of his shoulders and elbows for the past 5 days. The patient reports severe itching and burning sensation. He has no history of serious illness except for recurrent episodes of diarrhea and abdominal cramps, which have occurred every once in a while over the past three months. He describes his stools as greasy and foul-smelling. He does not smoke or drink alcohol. He does not take illicit drugs. He takes no medications. He is 180 cm 5 ft 11 in tall and weighs 60 kg 132 lb; BMI is 18.5 kgm2. His temperature is 37C 98.6F, pulse is 70min, and blood pressure is 11070 mm Hg. Physical examination shows a symmetrical rash over his shoulders and knees. A photograph of the rash on his left shoulder is shown. Rubbing the affected skin does not lead to upper epidermal layer separation from the lower layer. His hemoglobin concentration is 10.2 gdL, mean corpuscular volume is 63.2 μm3, and platelet count is 450,000mm3. Which of the following is the most appropriate pharmacotherapy for this skin condition?? A: Oral dapsone, B: Systemic prednisone, C: Oral acyclovir, D: Topical permethrin, E: Topical coal tar,  <response>: This is a clinical vignette describing a 22-year-old man with a 5-day history of an itchy, burning rash over his shoulders and elbows. He also has a 3-month history of recurrent diarrhea and abdominal cramps with greasy, foul-smelling stools. On exam he has a symmetrical rash over his shoulders and knees. Lab tests show mild anemia and thrombocytosis. Based on the symmetrical rash, abdominal symptoms, and lab abnormalities, this patient likely has dermatitis herpetiformis, which is the skin manifestation of celiac disease. The rash is caused by IgA deposits in the skin, and responds well to dapsone treatment. Oral steroids may help with itching but do not treat the underlying condition. Acyclovir treats herpes infections, not relevant here. Permethrin is for scabies, which does not cause abdominal symptoms or lab changes. Coal tar is used for psoriasis, which has a different rash morphology.A: Oral dapsone 