<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 65-year-old man with a history of myocardial infarction is admitted to the hospital for treatment of atrial fibrillation with rapid ventricular response. He is 180 cm 5 ft 11 in tall and weighs 80 kg 173 lb. He is given an intravenous bolus of 150 mg of amiodarone. After 20 minutes, the amiodarone plasma concentration is 2.5 mcgmL. Amiodarone distributes in the body within minutes, and its elimination half-life after intravenous administration is 30 days. Which of the following values is closest to the volume of distribution of the administered drug?? A: 17 L, B: 60 L, C: 10 L, D: 80 L, E: 150 L,  <response>: This is a pharmacokinetics question asking about the volume of distribution of amiodarone. To calculate volume of distribution, we need the dose administered, the plasma concentration achieved, and the elimination half-life. The question provides all this information - a 150 mg IV bolus dose resulted in a plasma concentration of 2.5 mcgmL at 20 minutes, and the elimination half-life is 30 days. With this data, we can calculate the volume of distribution using the formula: Vd Dose Plasma concentration. The choices provide different possible values for Vd, so we need to calculate it and choose the closest option.B: 60 L 