<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 23-year-old woman on prednisone for lupus presents to her primary care physician because she experiences a burning sensation with urination. She has also been urinating more frequently than normal. The patient denies fever, chills, nauseavomiting, abdominal or back pain, or other changes with urination. Her vital signs and physical exam are unremarkable, and her urine analysis is positive for leukocyte esterase and nitrites. The patient receives a diagnosis and is then prescribed an antimicrobial that acts by inhibiting DNA gyrase. Which adverse effect should the patient be counseled about?? A: Rhabdomyolysis, B: Leukopenia, C: Facial rednessflushing, D: Hemolytic anemia, E: Tendon rupture,  <response>: This is a patient with symptoms of a urinary tract infection UTI, including burning with urination and increased urinary frequency. The positive leukocyte esterase and nitrites on urinalysis support the diagnosis of a UTI. She is prescribed an antimicrobial that inhibits DNA gyrase, which indicates a fluoroquinolone antibiotic like ciprofloxacin. Fluoroquinolones are associated with an increased risk of tendon rupture, so this would be an important adverse effect to counsel the patient about.E: Tendon rupture 