<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 1-year-old boy is brought to the emergency room by his parents because of inconsolable crying and diarrhea for the past 6 hours. As the physician is concerned about acute appendicitis, she consults the literature base. She finds a paper with a table that summarizes data regarding the diagnostic accuracy of multiple clinical findings for appendicitis:Clinical finding Sensitivity SpecificityAbdominal guarding in children of all ages 0.70 0.85Anorexia in children of all ages0.75 0.50Abdominal rebound in children 5 years of age 0.85 0.65Vomiting in children of all ages 0.40 0.63Fever in children from 1 month to 2 years of age 0.80 0.80Based on the table, the absence of which clinical finding would most accurately rule out appendicitis in this patient?? A: Guarding, B: Fever, C: Anorexia, D: Rebound, E: Vomiting,  <response>: This is a question about using sensitivity and specificity data to determine which clinical finding would best rule out appendicitis in a 1-year-old boy. Sensitivity refers to the proportion of patients with the disease who test positive. A highly sensitive test will rarely miss patients with the disease. Specificity refers to the proportion of patients without the disease who test negative. A highly specific test will rarely falsely identify patients without the disease as having the disease.To rule out a disease, we want a test with high specificity, so that a negative test can reliably exclude the disease. Of the findings listed, fever has the highest specificity at 0.80. This means a 1-year-old without fever is unlikely to have appendicitis. Fever would be the best finding to rule out appendicitis in this patient.B: Fever 