<prompt> Please answer with one of the option in the bracket. Write reasoning in between . Write answer in between .Q:A 32-year-old woman presents to her gynecologist for an annual visit. She is currently sexually active with 3 men and reports the consistent use of condoms. She denies abnormal vaginal odor, discharge, or dysuria. A routine Pap test is performed, which shows atypical squamous cells of undetermined significance ASC-US. Her last Pap test was normal. A reflex human papillomavirus HPV test is negative. What is the best next step in the management of this patient?? A: Routine screening: repeat Pap test every 3 years, B: Colposcopy, C: Cervical biopsy, D: Repeat cytology and HPV testing in 3 years, E: Excisional treatment,  <response>: This is a patient with ASC-US on Pap smear but a negative HPV test. ASC-US indicates mild abnormalities that may be due to HPV infection or other causes. Since her HPV test is negative, this lowers her risk that these changes are due to a significant precancerous process. In a patient with ASC-US and negative HPV, guidelines recommend repeat co-testing with cytology and HPV in 3 years. Colposcopy, cervical biopsy, and excisional treatment are not indicated based on one ASC-US Pap result with negative HPV. D: Repeat cytology and HPV testing in 3 years 