<prompt> Mushure mokunge chirwere chacho chaenderera mberi, kusagadzikana kweuropi kunopindirana zvakanyanya nekusimudzirwa kwezvirwere zvemuviri, zvakadai se capillary basement membrane thickening uye endothelial hyperplasia, iyo inobatsira kuderedza kukanganiswa kwe okisijeni uye hypoxia. Neuronal ischemia chinhu chakanyatsogadziriswa chechirwere cheshuga cheshuga. Zvirwere zvemuviri semuenzaniso, ACE inhibitors, α1-antagonists zvinogona kutungamira mukuvandudzwa kwakanyanya kwekuyerera kweropa, pamwe nekuenderana nekuvandudzwa kwehutano hweropa. Saka, kusagadzikana kwemidziyo midiki kunoitika pakutanga, mukufanana nekufambira mberi kwechirwere cheshuga, uye shanduko dzakakwana dzingaonekwa mukutsigirwa kwechirwere cheshuga cheshuga. Mubvunzo: Chii chinofanira kuitwa mukutsigira chirwere cheshuga cheshuga, pamwe nekushomeka kwemitsipa, uye shanduko dzakakwana mukuita kwemitsipa dzetsinga?  <response>: kuyerera kweropa kwakakwana 