<prompt> Gadzira shanduro yakaoma zvikuru yemutsara uyu Kurwira simba pakati pePope neHoly Roman Empire kwakanga kwatanga neInvestiture Conflict iyo yakatanga muna 1075 ndokuguma neConcordat yeWorms muna 1122.  <response>: Zvechokwadi, shanduro yakaoma zvikuru yemutsara wacho ndeiyi Kurwira simba pakati pePope neHoly Roman Empire kwakanga kwamuka neInvestiture Conflict iyo yakatanga muna 1075 uye yakapera neConcordat yeWorms muna 1122, asi kupatsanurwa pakati peGuelphs neGhibellines muItaly kwakapfuurira kusvika muzana remakore rechi15. 