<prompt> Kuvakira pfungwa dzake pamusoro avo amutangira akadai Williamson, Edward Frankland, William Odling, Auguste Laurent, Charles-Adolphe Wurtz nevamwe, Kekulé aiva chikuru formulator of dzidziso makemikari mamiriro 185758. dzidziso iyi kunobva pfungwa maatomu valence, kunyanya tetravalence kabhoni izvo Kekulé akazivisa mukupera 1857 uye mano kabhoni maatomu kubatanidza kune mumwe nomumwe yakabudiswa mupepa muna 1858, asi akanga achiri achishingaira basa zvakananga pakusarudza kubatana ose maatomu ari makemikari mamorekuru. Archibald Couperland, William Odling, Auguste Laurent, Charles-Adolphe Wurtz nevamwe, Kekulé aiva chikuru formulator of dzidziso makemikari mamiriro 185758. Zvisinei, Kekulé akanga asina kunyanya kuvimba nemakemikari pfungwa, kunyanya kubva pane zvaakanga achangobva kugadzira, kunyanya panguva yebasa raAlexander C. Couperland, Kekulé akanga asina kunyanya kuvimba nedzimwe nzira dzinoshandiswa pakutsvakurudza chimiro chemakemikari, kunyanya kubva pane zvaakanga dzatanga kuzivikanwa kare  <response>: chimiro chemakemikari 