<prompt> Mushure mekunge chirwere ichi chaenderera mberi, kusagadzikana kwechirwere chechirwere kunopindirana zvakanyanya nekuvandudzwa kwezvinhu zvisiri izvo zvemidziyo yeropa, zvakadai se capillary basement membrane thickening uye endothelial hyperplasia, iyo inobatsira kuderedza kukanganiswa kwe okisijeni uye hypoxia. Neuronal ischemia chinhu chakanyatsogadziriswa chechirwere cheshuga cheshuga. Zvirwere zvemuviri semuenzaniso, ACE inhibitors, α1-antagonists zvinogona kutungamira mukuvandudzwa kwakanyanya kwekuyerera kweropa, pamwe nekuenderana nekuvandudzwa kwehutachiona hweropa. Saka, kusagadzikana kwemidziyo yeropa kudiki kunoitika pakutanga, mukufanana nekufambira mberi kwechirwere cheshuga yeropa, uye shanduko dzakaratidzwa mukuomarara kwechirwere cheshuga yeropa. Mubvunzo ndewekuti, kukosha kwakadii kwechirwere cheshuga yeropa kunogona kucherechedzwa mukutsigirwa kwemidziyo weropa, pamwe nekusagadzikana kwemidziyo yeropa, uye hurema hwekurwere hwechirwere cheshuga yeropa  <response>: chirwere ichi chinogona kutsigira kuoma kwechinjo dzomuviri, dzinoshanda, uye dzemakiriniki dzinocherechedzwa muchirwere cheshuga chetsinga. 