<prompt> Pfupisa nyaya yacho: Vakadzi vane pamuviri vakanyeverwa kuti rudzi rwomushonga unorwisa mabhakitiriya runogona kukuvadza mwana wavo asati aberekwa. Vanzveri veGreat Ormond Street Hospital neUniversity College London vakabatanidza mapiritsi eerythromycin nefivhiri uye kuoma rutivi rwomuviri. Fundo yacho yakatevera utano hwavana vakaberekwa kuvakadzi veBritain 200 000. Pamwe chete, vana vakaberekwa nevakadzi vaitora mishonga inorwisa mabhakitiriya vakanga vasinganyanyi kurwara nepfari kana kuti cerebral palsy. Vakadzi vakanyeverwa kuti mushonga unorwisa mabhakitiriya unonzi erythromycin unogona kukuvadza mwana wavo asati aberekwa mufananidzo womufaira Asi vakadzi vairapwa neerythromycin nemamwe mapiritsi anobva mumhuri yemishonga inorwisa mabhakitiriya inonzi macrolide vakanga vane mikana yakapetwa kaviri yokuva nomwana ane chimwe chezvinhu izvi kupfuura avo vakapiwa penicillin. Kuongorora kwacho, kwakabudiswa mumagazini inonzi PLOS ONE, kwakaratidza kuti chikamu chimwe muzvitatu chavanaamai vaiva nepamuviri chakapiwa mishonga inorwisa mabhakitiriya panguva yokuzvitakura, kazhinji kacho penicillin. 7 muzana bedzi yavakadzi vakapiwa mishonga inorwisa mabhakitiriya vakapiwa macrolides, ayo anoshandiswa kurapa utachiona hwomudumbu uye hwepachipfuva uye anonyanyoda kupiwa mukati mokurwara kunodzokororwa kana kuti kana mukadzi ane utachiona hwepenicillin. Zvisinei, pavakadzi 150 voga voga vakapiwa macrolide panzvimbo pepenicillin, paiva nomwana mumwe akaberekwa aine cerebral palsy kana kuti pfari. Muzvinadzidzo anotsvakurudza Ruth Gilbert akarayira vakadzi vane pamuviri kuti varambe vachitora mishonga inorwisa mabhakitiriya yavanenge vapiwa sezvo utachiona hungagona kukuvadza mwana wavo. Erythromycin ndeyemhuri yemakerolide yemishonga inorwisa mabhakitiriya. Macrolides anoshandiswa kurapa utachiona hwomudumbu uye hwomudumbu uye anonyanya kupiwa panguva yokurwara kunodzokororwa kana kuti kana mukadzi ane utachiona hwepenicillin. Uye akasimbisa kuti ngozi ipi neipi yakawedzerwa kumwana asati aberekwa yaizomutswa nemapiritsi yaizova duku zvikuru. Zvisinei, nezvidzidzo zvina zvapakuvamba zvinomutsa funganyo pamusoro pemapiritsi, akati yakanga yava nguva yokuti mapiritsi acho aongororwe zvakakwana neMedicines and Healthcare Products Regulatory Agency MHRA. Purofesa Andrew Whitelaw, weBristol University, akanyevera kuti utachiona hwakakomba hungaguma hwauraya vose vari vaviri amai na...  <response>: Erythromycin mushonga unorwisa utachiona unopiwa pakurwara nemudumbu kana kuti muchibereko. Inonyorerwa panguva yokurwara kunodzokororwa kana kuti kuvanhu vane utachiona hwepenicillin. Vatsvakurudzi vakakumbira kuongororwa kwakachengeteka asi vakasimbisa kuti ngozi yakawedzerwa iduku. Kazhinji, kuongorora kwakawana kuti mishonga inorwisa mabhakitiriya yakatorwa mukati mokubata pamuviri yakanga yakachengeteka. 