<prompt> Pfupisa nyaya yacho: Kurapa kwokutanga kwakananga kurapa migraine kwakagadzirwa - budiriro inonzi nenyanzvi inokosha zvikuru. Mushonga mutsva uyu unopa tariro kumazana ezviuru zvevanhu vanotambura nemigraine isingaperi - rudzi rwemusoro unonyanya kurwadza. Mushonga wacho unogadzirwa nemapuroteni eropa. Aya maantibody - mapuroteni anogadzirwa nomuviri kuti arwise majekiseni - akanyatsogadzirirwa kurwisa makemikari anokonzera migraines. Mapuroteni acho anokwanisakupukutaimwe puroteni inonzi calcitonin gene- related peptide CGRP, iyo inokonzera marwadzo, kusvotwa uye kurutsa zvinokonzerwa nemigraine. Mushonga mutsva wokudzivirira migraine wakatanga kugadzirwa, uye nyanzvi dziri kuti uyu mushongamutsva. Muongororo yakaitwa pavanhu 172 vane migraine, masayendisiti akawana kuti mushonga uyu wakaderedza zvikuru maawa nemazuva anoshandiswa nevanorwara nemigraine. Sangano reInternational Headache Society rinorondedzera kupera musoro kusingaperi sokurwadziwa nomusoro kwemazuva anopfuura 15 pamwedzi mukati memwedzi mitatu - mazuva anopfuura masere - kana zvikarambidzwa kuti kupera musoro kwacho kunokonzerwa nokunyanyisa kushandisa mishonga. Migraine kurwadziwa nomusoro kwakasimba kunodzokororwa, kazhinji kunobata rutivi rumwe chete rwomusoro, kunoratidzirwa nokurwadziwa kwakasimba uye kazhinji kunoperekedzwa nokurutsa, kurutsa, uye zvinetso zvokuona. Maererano neWorld Health Organization WHO, vanhu vakuru vanosvika 4 muzana munyika yose vanorwadziwa nemusoro mazuva 15 kana kupfuura mwedzi woga woga. Yakaratidza kuti migraine isingaperi inokonzera kuremara kupfuura upofu, paraplegia angina kana kuti rheumatoid arthritis. Yakarongawo migraine pamwero wakaenzana wokuremara sedementia, quadriplegia uye acute psychosis. Uye vanhu vane migraine kana kuti misoro inorwadza zvikuru vane mukana wakakura wokunyanya kuora mwoyo kupfuura vanhu vane utano hwakanaka, inonyevera kudaro WHO. Izvi zvinogona kuita kuti vanorwara vacho vaore mwoyo uye vatadze kutsungirira, rinodaro sangano rinoyamura rinonzi The Migraine Trust. Nepo pesvedzero dzomukati kana dzokunze dzinga...  <response>: Migraine inokonzerwa necalcitonin gene-related peptide CGRP protein. Izvi zvinowedzera mitsipa yeropa iri pedyo nemitsipa iri mumusoro, zvichikonzera kurwadziwa. Mushonga mutsva uyu une mapuroteni eropa akafanana nemamwe. Aya ndiwo maantibody akagadzirwa kuti asunge CGRP uye anogonakuibvisa Miedzo yakawana kuti kurapa kwacho kwakaderedza zvikuru migraines muvarwere. 