<prompt> Gadzira shanduro yakaoma zvikuru yemutsara uyu Ring chromosome 14 syndrome isingawanzoitiki zvikuru.  <response>: Chokwadika, shanduro yakaoma zvikuru yemutsara wacho ndeiyi Ring chromosome 14 syndrome is extremely rare, the true rate of occurrence is unknown, but there are at least 50 documented cases in the literature. 