<prompt> Pedzisa mutsara unotevera: Akapfekedzwa korona saMambo muGermany, Charles akatsigira Papa Leo X uye akazivisa kuti Martin Luther akanga asiri pamutemo paDate of Worms 1521. Mugore iroro, Francis I weFrance, akanga akakomberedzwa nezvinhu zvevaHabsburg, akatanga kurwisana muLombardy kwakapfuurira kusvikira paHondo yePavia 1525, iyo yakatungamirira kukuiswa mutorongo kwenguva pfupi kwamambo weFrance. Nyaya yechiPurotesitendi yakabudazve muna 1527 sezvo Roma yakapambwa neuto ravarwi vaCharles vakapanduka, zvikurukuru vorudzidziso rweLutheran. Pashure pokunge mauto ake abva muPapal States, Charles V  <response>: akadzivirira Vienna kubva kuvaTurkey ndokuwana kugadzwa samambo muItaly naPapa Clement VII. Muna 1535, akabatanidza Duchy reMilan rakanga risina munhu ndokutora Tunis. Kunyange zvakadaro, kurasikirwa kweBuda panguva yekurwira Hungary uye kuAlgiers expedition mukutanga kwema1540 kwakakanganisa marongero ake ekurwisa maOttoman. Munguvayi, Charles V akanga asvika pachibvumirano naPapa Paul III nokuda kwesangano reCouncil of Trent 1545. Kuramba kweLutheran Schmalkaldic League kubvuma kushanda kwedare kwakatungamirira kuhondo, yakakundwa naCharles V nokuiswa mutorongo kwamadzishe ePurotesitendi. Zvisinei, Henry II weFrance akapa rutsigiro rutsva kuchinangwa cheLutheran ndokusimbisa mubatanidzwa wapedyo nesultan Suleiman the Magnificent, mutongi woUmambo hweOttoman kubvira muna 1520. 