<prompt> Lithini igama le-hydrolase elibhubhisa izindonga zamangqamuzana amagciwane, elitholakala ezinyembezi? Njengoba kunikezwe umbuzo odlule, bhala umongo onempendulo yawo. Kungaba imisho engu-1 kuya kwengu-20. Umongo:  <response>: Izithiyo zamakhemikhali nazo ziyavikela ekungenweni izifo. Isikhumba nendlela yokuphefumula zikhipha ama-peptide alwa namagciwane njenge-β-defensins. Ama-enzyme anjenge-lysozyme ne-phospholipase A2 asemthonjeni, izinyembezi, nobisi lwebele nawo anamandla okulwa namagciwane. Uketshezi lwesitho sangasese sowesifazane lusebenza njengesithiyo samakhemikhali ngemva kokuya esikhathini, lapho luba ne-asidi encane, kuyilapho isidoda siqukethe ama-defensin ne-zinc ukuze kubulawe amagciwane. Esiswini, i - gastric acid nama - protease asebenza njengezivikelo zamakhemikhali ezinamandla ngokumelene namagciwane adliwayo. 