<prompt> Ukudlula: Ukulandelana kwezingqimba ze-DNA ezakha ukwakheka okuhlosiwe kuklanywa ngekhompyutha, kusetshenziswa imodeli yamangqamuzana kanye nesoftware yokumodela ye-thermodynamic. Ama-nucleic acid ngokwawo abese ahlanganiswa kusetshenziswa izindlela ezijwayelekile zokuhlanganiswa kwe-oligonucleotide, imvamisa ezenzakalelayo ku-synthesizer ye-oligonucleotide, futhi izingqimba zokulandelana ngokwezifiso ziyatholakala kwezentengiselwano. Izingqimba zingahlanjululwa ngokuhlanjululwa kwe-gel electrophoresis uma kunesidingo, futhi ukuhlushwa okunembile kunqunywe nganoma yiziphi izindlela eziningana ze-nucleic acid quantum ngokusebenzisa i-ultraviolet absorbance spectroscopy. Izakhiwo ezihlosiwe ngokuphelele zingaqinisekiswa kusetshenziswa i-gel electrophoresis yendabuko, enikeza ubukhulu nokuma kolwazi lwe-nucleic acid complexes. Ukuhlolwa kokuhamba kwe-electropetic kungakwazi ukuhlola ukuthi ngabe isakhiwo esihlosiwe  <response>: ukuthi isakhiwo sihlanganisa zonke izintambo ezifiselekayo 