<prompt> Yimaphi ama-hormone alandelayo angavumeli ukuxhumana phakathi kwama-APC nama-T-cell: i-leptin, i-prolactin, noma i-epinephrine? Njengoba kunikezwe umbuzo odlule, bhala umongo onempendulo yawo. Kungaba imisho engu-1 kuya kwengu-20. Umongo:  <response>: Ngaphezu kwemiphumela engemihle yokuntuleka kokulala, ukulala kanye nesimiso semijikelezo yansuku zonke esixhumene kuye kwaboniswa ukuthi kunemiphumela enamandla yokulawula imisebenzi ye-immunological ethinta kokubili amasosha omzimba angokwemvelo nawokuzivumelanisa nezimo. Okokuqala, phakathi nesigaba sokuqala sokulala ngegagasi elincane, ukwehla okungazelelwe kwamazinga e-cortisol, e-epinephrine, ne-norepinephrine egazini kubangela ukwanda kwamazinga e-leptin, i-pituitary growth hormone, ne-prolactin. Lezi zimpawu ziholela esimweni sokuvuvukala ngokukhiqizwa kwama-cytokine okuvuvukala i-interleukin-1, i-interleukin-12, i-TNF-alpha ne-IFN-gamma. La ma-cytokine abe eseshukumisa imisebenzi yamasosha omzimba njengokusebenza kwamangqamuzana omzimba, ukwanda, nokuzihlukanisa. Kulesi sikhathi lapho okungahlukanisiwe, noma okungahlukanisiwe kangako, njengamaseli we-T angenalutho futhi asemqoka, aphezulu okungukuthi ngesikhathi sokuphendula kwamasosha omzimba okuguquguqukayo kancane. Ngaphezu kwalokhu, ama-hormone akhiqizwa ngalesi sikhathi i-leptin, i-pituitary growth hormone, ne-prolactin asekela ukusebenzelana phakathi kwama-APC nama-T-cell, ukushintsha kwe-Th1Th2 cytokine balance iye kuleyo esekela i-Th1, ukwanda kokwanda kwe-Th cell jikelele, kanye nokufuduka kwama-T cell angakaze asebenze kuma-lymph node. Kucatshangwa nokuthi le ndawo isekela ukwakheka kwenkumbulo yesikhathi eside yomzimba ngokusebenzisa ukuqala kokuphendula komzimba kwe-Th1. 