<prompt> Bheka isigaba esingezansi bese uphendula umbuzo ngokulandelayo ngolimi olufanayo nesigaba: Isigaba: I-genome yomuntu iqukethe uhlelo lwama-gene angama-25,000 asebenza ngokubambisana ukukhiqiza uhlelo lwama-1,000,000 amaprotheni ahlukene. Lokhu kungenxa yokuhlanganiswa okuhlukile, futhi ngoba amangqamuzana enza izinguquko ezibalulekile kumaprotheni ngokuguqulwa kwe-posttranslational ngemuva kokuwakha okokuqala, ngakho-ke i-gene elinikeziwe lisebenza njengesisekelo sezinguqulo eziningi ezingenzeka zeprotheni ethile. Kunoma ikuphi, ukuhlolwa kwe-mass spectrometry eyodwa kungakhomba mayelana Umbuzo: Yisiphi isimo esibizwa ngamangqamuzana enza izinguquko ezibalulekile phakathi kwawo?  <response>: ukuguqulwa kwangemva kokuhumusha 