<prompt> Fingqa isihloko: Ososayensi banempumelelo engavamile ekwelapheni umdlavuza ngemithi yokugoma emisha abakholelwa ukuthi ingaba umshintshi womdlalo empini yokulwa nalesi sifo. Baye bathola indlela yokufundisa isimiso somzimba sokuzivikela ukuba sibone amangqamuzana omdlavuza, okuvumela iziguli ukuba zilungiselelwe ukubhubhisa umdlavuza. Kwesinye isenzakalo owesifazane waseMelika onikwa amasonto ambalwa kuphela okuphila wasuswa esifweni somdlavuza wegazi osezingeni eliphezulu. Usaphila ngemva kweminyaka emithathu, futhi udokotela wakhe uthi akukhona ukuthi kwenzeka kanye kuphela. Ososayensi banempumelelo engavamile ekwelapheni umdlavuza ngemithi yokugoma emisha abakholelwa ukuthi ingaba umshintshi womdlalo empini yokulwa nalesi sifo. Manje abacwaningi baseBrithani basebenza ngendlela efanayo. Zombili lezi zindlela zihlanganisa ukuthatha amangqamuzana e-T, alwa namagciwane, futhi awanike amandla okubona umaki okhethekile osendaweni yamangqamuzana omdlavuza, obizwa ngokuthi iprotheni i-WT1. Lolu cwaningo lwenziwa ezigulini ezinomdlavuza wegazi. Kodwa ososayensi banethemba lokuthi imithi yabo yokugoma ekugcineni iyosetshenziselwa ukulwa nezinhlobo eziningi zomdlavuza, kuhlanganise nomdlavuza webele, wamathumbu nowendlala yesinye amaseli awo avame ukuba ne-WT1 ebusweni bawo. Kukhona ngisho nokukhuluma ngomuthi wokugomela umdlavuza wendawo yonke phakathi kwabanye ososayensi, nakuba abacwaningi ngokwabo bekholelwa ukuthi akunakwenzeka lokho. Lezi zindlela zokwelapha zenzelwe ukusiza amasosha omzimba ukuba athole futhi abhubhise amangqamuzana omdlavuza. Lokhu bakwenza ngokunikeza amangqamuzana e-T ikhono lokuthola umaki oyisihluthulelo obizwa ngokuthi i-WT1. Ukufuna nokubulala: Amangqamuzana e - T angafundiswa ukuba abone bese ebulala amangqamuzana omdlavuza. I-WT1 iyiprotheni etholakala ebusweni bamangqamuzana ezinhlobo eziningi zomdlavuza. Amangqamuzana e- T awuhlobo lwamangqamuzana amhlophe egazi, alwa nezifo noma izinsongo. Ukumpontshelwa kwamangqamuzana omnikeli angaguqulwa abe amangqamuzana e-T nakho kungasetshenziselwa ukuqinisa amasosha omzimba. Eminyakeni emithathu edlule, uchwepheshe uGuenther Koehne, weMemorial Sloan Kettering Cancer Center eNew York, uye welapha iziguli ezingu-15 ezinomdlavuza wamangqamuzana e-plasma ngama-T-cell afundiswe ukuqaphela umdlavuza. Lesi sifo singelashwa ngemithi efana neyokwelapha ngamakhemikhali kodwa sivame ukubuya. Bonke abangu-15 babe...  <response>: Ochwepheshe bathole indlela yokufundisa isimiso somzimba sokuzivikela ekulimaleni amangqamuzana omdlavuza. Intuthuko entsha kwezokwelapha ivumela iziguli ukuba zilungiselelwe ukubhubhisa umdlavuza. Kwelinye icala, owesifazane wanikezwa amasonto ambalwa okuphila esekhululiwe kumdlavuza wegazi osezingeni eliphezulu. Isiguli sase-US sisaphila eminyakeni emithathu kamuva, futhi odokotela bathi akusiyo into eyenzeka kanye kuphela. 