<prompt> Bhala okuqhubekayo ngalesi sigaba - IPanama yayihlala izizwe zomdabu ngaphambi kokufika kwamakoloni aseSpain ngekhulu le - 16. Lahlukana neSpain ngo-1821 futhi lajoyina iRiphabhuliki yaseGran Colombia, inyunyana yaseNueva Granada, i-Ecuador neVenezuela. Ngemva kokuba iGran Colombia ichithekile ngo-1831, iPanama neNueva Granada ekugcineni zaba iRiphabhuliki yaseColombia. Ngokusekelwa yi-United States, iPanama yahlukana neColombia ngo-1903, yavumela ukwakhiwa kwePanama Canal ukuba kuqedwe yi-US Army Corps of Engineers phakathi kuka-1904 no-1914. Izivumelwano zikaTorrijos-Carter zango-1977 zavuma ukudlulisela umsele usuka e-United States uye ePanama ngo-December 31, 1999. Indawo ezungezile  <response>: yabuyiselwa okokuqala ngo-1979. 