<prompt> Bhala okuqhubekayo kwalesi sigaba - uPtolemy IV wayeyingane yesibili nendodana endala kaPtolemy III nomkakhe uBerenice II. Wazalwa cishe ngemva kweminyaka emibili uyise engene esihlalweni sobukhosi saseGibhithe. UPtolemy IV wayenodadewabo omdala, u-Arsinoe III, nabafowabo abathathu abancane, uLysimachus igama elingaqinisekile, u-Alexander noMagas, bonke abazalwa ngawo-240 BC. Umkhaya wonke ukhunjulwa ngamaqembu ezifanekiselo amiswa eThermos naseDelphi yi - Aetolian League. Ngaphansi kukaPtolemy III, umbuso kaPtolemy wawusufinyelele ukuphakama kwawo, wanqoba ngokunqobayo umbuso wamaSeleucid owawuphikisana neMpi Yesithathu yaseSyria 246241 BC, waxhasa ukumelana kwezwe laseGrisi ne-Antigonid Macedonia, futhi wagcina ukulawula cishe lonke ugu olusempumalanga yeMedithera. Kodwa-ke ukubusa kwaphawulwa futhi ukuvukela kokuqala kwamaGibhithe endabuko ngokumelene nokubusa kukaPtolemy, ngo-245 BC. Eminyakeni yokugcina yokubusa kukaPtolemy III, iMpi kaCleomenean  <response>: 229222 BC kwaqubuka eGrisi futhi, naphezu kokuthola ukwesekwa okukhulu kukaPtolemy, uCleomenes III waseSparta wayehluliwe ngokuphelele yiqembu elaliholwa yi-Antigonid futhi waphoqeleka ukuba abalekele eGibhithe. 