<prompt> Bhala ukuqhubeka kwalesi sigaba - UJohn Snow 15 Mashi 1813 16 Juni 1858 wayengudokotela waseNgilandi futhi engumholi ekuthuthukiseni i-anesthesia nenhlanzeko yezokwelapha. Ubhekwa njengomunye wabasunguli be-epidemiology yanamuhla, ngokwengxenye ngenxa yomsebenzi wakhe wokulandelela umthombo wokuqubuka kwekholera eSoho, eLondon, ngo-1854  <response>: , ayiqeda ngokususa isibambo sepompo yamanzi. Okutholwe uSnow kwabangela ukuba kusetshenziswe i-anesthesia kanye nezinguquko ezinkulu ezimisweni zamanzi nezokuthuthwa kwendle eLondon, okwaholela ezinguqukweni ezifanayo kwamanye amadolobha, nasekuthuthukeni okukhulu kwezempilo yomphakathi jikelele emhlabeni wonke. 