<prompt> Yakha inguqulo eyinkimbinkimbi yalesi sigwebo I-Semaphorin - neuropilin repulsive signaling isebenza ngokubambisana ne-EphB signaling ukuqondisa amangqamuzana e-neural crest phansi engxenyeni ye-rostral yama-somites kumagundane.  <response>: Yiqiniso, inguqulo eyinkimbinkimbi yalesi sigwebo ithi I-Semaphorin - I-Neuropilin isebenza ngokubambisana nesignali ye-EphB yangaphambili ukuze iqondise amangqamuzana e-crest ye-neural phansi kwesigamu se-rostral somites kumagundane; emibungu yenkukhu, i-semaphorin isebenza esifundeni se-cephalic ukuze iqondise amangqamuzana e-crest ye-neural ngokusebenzisa ama-pharyngeal arches. 