<prompt> Fingqa isihloko: Abacwaningi bathi abesifazane abathatha i-HRT banganciphisa ingozi yesifo senhliziyo nokufa ngaphambi kwesikhathi uma nje beqala eminyakeni yabo yama-50. Imininingwane yeziguli ezingu - 40 000 yathola ukuthi labo ababesebenzisa le mithi kusukela kulesosikhathi babenamathuba amancane okufa ngaphambi kwesikhathi nganoma yisiphi isizathu futhi ingozi yokuhlaselwa yisifo senhliziyo yayincishiswe ngesigamu. Kodwa-ke, kwakukhona ingozi ekhuphuke kancane yama-clots egazi. Kulinganiselwa ukuthi abesifazane abayisigidi eBrithani basebenzisa ukwelashwa kwama-hormone ukuze balawule izimpawu zokunqamuka kokuya esikhathini futhi ochwepheshe bakholelwa ukuthi ukuwasebenzisa uma usuneminyaka engu-50 ubudala kungasiza ekunciphiseni ingozi yokufa ngaphambi kwesikhathi nokuhlaselwa yisifo senhliziyo. I-HRT inikezwa ukulawula izimpawu zokunqamuka kokuya esikhathini futhi ngokuvamile ithathwa ngabesifazane abasanda kweva eminyakeni engu-50. Lokhu kubuyekezwa okukhulu kwahlose ukuhlola ukuthi kunemiphumela emihle noma emibi yini kwezinye izindawo zempilo yabesifazane. Lapho kuhlolwa ubufakazi obuvela kubantu abaneminyaka yobudala ehlukahlukene, kwabonisa ukuthi i-HRT ethathwa ngomlomo ayizange ivikele ezifweni zenhliziyo futhi ingandisa ingozi yesifo sohlangothi. Kodwa imiphumela ezuzisayo yaba sobala eqenjini labesifazane abangu - 9 000 abaqala ukwelashwa nge - HRT ngesikhathi noma ngemva nje kokuyeka ukuya esikhathini nangaphambi kokuba babe neminyaka engu - 60. Bayithatha iminyaka emithathu kuya kweyishumi. Umcwaningi oholayo uDkt. Henry Boardman, wase-Oxford University, wathi: Ubufakazi esinabo bunikeza ukusekela okuthile kulokho okubizwa ngokuthi umbono wesikhathi kodwa kufanele sikhumbule ubukhulu balomphumela. Lapho sibheka imiphumela ngokweminyaka yabesifazane, noma ukuthi sekuyisikhathi esingakanani beyekile ukuya esikhathini ukuthi baqala ukwelashwa, sathola ukuthi uma abesifazane abangu-1 000 abangaphansi kweminyaka engu-60 beqala ukwelashwa singalindela ukufa okungu-6 okuncane, amacala ayisishiyagalombili okunciphisa isifo senhliziyo kanye nama-clots egazi ayisihlanu ngaphezulu kweminyaka engaba yisikhombisa, uma kuqhathaniswa nabesifazane abangu-1 000 abafanayo abangazange baqale ukwelashwa. Kulinganiselwa ukuthi abesifazane abayisigidi e-UK bathatha i-HRT ngenxa yezimpawu ezinjengokushiswa yilangabi nokushintsha kwemizwelo nakuba ivikela namathambo. Nokho, sekuyisikhathi eside abanye ochwepheshe bethi i-HRT kufanele ivimbele isifo senhliziyo ngenxa yokuthi lapho abesifazane ngokwemvelo belahlekelwa ama-estrogen lapho beya esikhathini, izingozi zabo zenhliziyo ziyanda. I-HRT inikezwa ukulawula izimpawu ze...  <response>: Abesifazane abathatha i-HRT lapho sebeneminyaka engu-50 ubudala banganciphisa ingozi yesifo senhliziyo nokufa ngaphambi kwesikhathi. Imininingwane yeziguli ezingu - 40 000 yathola ukuthi labo ababethatha amaphilisi babenobungozi obuncane. Ochwepheshe bathola ukuthi kunengozi encane yokuba nama-blood clots. Kulinganiselwa ukuthi abesifazane abayisigidi e-UK bathatha i-HRT ngenxa yezimpawu zokuya esikhathini. 