<prompt> Fingqa isihloko: Uma ungakwazi ukulahla isisu sakho, kungakhathaliseki ukuthi uzama kanzima kangakanani, usole i-Plexin D1 gene yakho. Ososayensi bakholelwa ukuthi le-gene itshela amafutha ukuba ahlangane phakathi, kunasezansi nasezinqeni. Ngamanye amazwi, kunomthelela ekutheni umuntu uyisibungu yini, esinesisu esikhulu, noma uyisibungu, esivuleka ngezansi okhalweni. Lokhu kuphakamisa ithuba lamaphilisi avimbela amafutha ukuba agcinwe okhalweni okusho ukuphela kwezisu zezimbiza nezingqimba zamakhekhe. Ukuma kwe - apula: Ososayensi baye bathola ukuthi i - gene ebizwa ngokuthi i - Plexin D1 ithonya ukuthi umuntuuyi - apula yini, elinesisu esikhulu, nomauyi - pear enamafutha ezinqeni nasezinqeni. Futhi izinzuzo zazingeke nje zibe ezobuhle. Ukutholakala kofuzo lwe-apple-shape kubalulekile ngoba ukuba yi-apple egcina amafutha phakathi kuyingozi empilweni kunokuba yi-pear. Ngokungafani namafutha akha ama-pear-shaped pads, amafutha esiswini azungeza izitho zomzimba ezibalulekile futhi akhiqiza ama-hormone namanye amakhemikhali athonya umfutho wegazi, i-cholesterol, namazinga kashukela egazini. Ngenxa yalokho kwandisa ingozi yezinkinga eziningi zempilo ezihlanganisa isifo senhliziyo, isifo sikashukela nesifo sohlangothi. Ukuze baqonde ukuthi amafutha agcinwa kanjani, abacwaningi base - United States bafunda izinhlanzi okuthiwa ama - zebra, izinhlanzi ezincane zasezindaweni ezishisayo ezinemizimba esobala ezenza zibone ukusebenza kwazo kwangaphakathi. Ngokusebenzisa umbala owenza amangqamuzana amanoni akhanye, babonisa ukuthi izinhlanzi ezingenawo ufuzo olubizwa ngokuthi i-Plexin D1 zazinamafutha amancane kakhulu esiswini kunokujwayelekile. I-Muffin top: Amafutha asemaphakathi ayingozi empilweni njengoba azungeza izitho ezibalulekile, futhi akhulisa ingozi yezinkinga zempilo ezihlanganisa isifo senhliziyo, isifo sikashukela kanye nesifo sohlangothi. Kunalokho, amafutha ayegcinwe ngendlela enjengebheya, kubika iphephabhuku i-Proceedings of the National Academy of Sciences. Izinhlanzi ezazingenalo ufuzo olunjengolwe-apula nazo zaziwusebenzisa kangcono ushukela - okuyinto okufanele inciphise amathuba okuba nesifo sikashukela. Njengoba kucatshangwa ukuthi i-Plexin-1 gene inendima efanayo kubantu, lolu cwaningo lwenza kube lula ukuthola umuthi ovimbela abantu ukuba babe nezisu ezinkulu. Umcwaningi uDkt...  <response>: Ufuzo lwe - plexin D1 lunomthelela ekutheni umuntuunjenge - apula nomaunjenge - pearyini. Ukutholakala kwaso kuphakamisa ithuba lamaphilisi okuvimbela amafutha ukuba agcinwe esiswini. Ngokungafani namafutha asezinqeni nasezinqeni, amafutha esiswini azungeza izitho ezibalulekile. Kwenyusa ingozi yezifo ezihlanganisa isifo senhliziyo, isifo sikashukela nesifo sohlangothi. 