<prompt> Qedela umusho olandelayo:  <response>: Ukuqubuka okukhulu kwenzeka eLondon ngo-1854, uDkt. UJohn Snow waqoqa idatha mayelana namacala ngamanye, ikakhulukazi indawo yawo eSoho eLondon, esebenzisa izindlela ezintsha zokuhlaziywa kwendawo nokulandela umkhondo wokuthintana ukuze aphethe ngokuthi amanzi angcolisiwe yi-vector yesifo, futhi waphumelela ukuvala umthombo. Imephu eyayihambisana nombiko wakhe wango - 1855 yayibonisa izigameko ngazinye, zihlanganiswe endaweni ngayinye yendlu, zibonisa ngokucacile ukugxila ezungeze i - Broad Street Pump kanye nezikhala ezindaweni ezazineminye imithombo yamanzi. Ibalazwe manje selidunyiswa njengelishintshayo; nakuba indima yalo ekuphenyweni ngokwako nomphumela walo ekuxazululeni impikiswano ngesizathu salesi sifo kuvame ukucatshangelwa ngokweqile, lifanelwe ukuqashelwa ngokuqonda kukaSnow ukuthi ibalazwe laliyithuluzi elisebenza kahle kakhulu lokuxhumana namaphethini endawo yalesi sifo. 