<prompt> Fingqa isihloko: Umuthi omusha ofakwa ngomjovo owenzelwe ukuqeda ama-chins amabili ngaphandle kokuhlinzwa wanconywa ngazwi linye ukuba uvunyelwe ikomiti eyelulekayo ye-Food and Drug Administration kuleli sonto. Lesi sidakamizwa, manje esaziwa ngokuthi i-ATX-101, manje sidinga kuphela ukuthola imvume yokugcina ye-FDA ngaphambi kokuba sitholakale emphakathini. Ngokungafani nokuhlinzwa kwesilevu esiphindwe kabili kwamanje, okudinga ukuba odokotela basikhiphe noma basisule, i-ATX-101 iyoba yinqubo engahlaseli, eyenziwa ehhovisi, ngokusho kukaDkt. Susan Weinkle. Skrolela phansi ukuze ubone ividiyo. Udokotela wesikhumba ulungiselela indawo yomjovo we - ATX-101, umuthi omusha ofakwa ngomjovo owenzelwe ukuqeda izihlathi eziphindwe kabili ngaphandle kokuhlinzwa okwanconywa ngazwi linye ukuba kuvunyelwe ikomiti eyelulekayo ye - FDA. I-ATX-101 isebenza ngokuqeda ulwelwesi lwamangqamuzana amafutha ngaphansi kwesilevu esiphindwe kabili. Lokhu kubangela ukuba ingqamuzana lamafutha liqhume, lilichithe unomphela. Imiphumela engemihle ihlanganisa ukuvuvukala okwesikhashana, ukulimala nokungazweli. UWeinkle, udokotela wesikhumba obelokhu esebenza nge-ATX-101 kusukela ngo-2007, wathi abantu abaningi banamafutha ngaphansi kwesilevu, ngisho noma bengenawo amafutha emzimbeni wabo wonke, etshela i-ABC News. Ukuze afake umuthi, uWeinkle uphawula indawo lapho ebona khona inani elikhulu lamafutha ngetshe lamaphoyinti amancane, asebenza njengezindawo zokujova i-ATX-101. UWeinkle uthi inqubo ithatha imizuzu emihlanu kuphela futhi iziguli ziphola ezinsukwini ezimbili kuya kwezintathu - futhi akudingeki nokuba zigqoke ibhandishi. Umuthi uyinhlanganisela ye - deoxycholic acid,i - molecule engokwemvelo esiza imizimba yethu ukuba ichithe amafutha esiwathola ekudleni, ngokusho komkhiqizi i - KYTHERA Biopharmaceuticals. UDkt. Derek Jones, owanikeza i-ATX-101 i-FDA, wathi lesi sidakamizwa sibulala ulwelwesi lwamangqamuzana amafutha angaphansi kwesilevu esiphindwe kabili. Ukwelashwa nge-ATX-101 kuthatha imizuzu emihlanu kuphela ukukunikeza nezinsuku ezimbili kuya kwezintathu ukuze kwelaphe. Lokhu kubangela ukuba ingqamuzana lamafutha liqhume. Izinsalela zalo zibuyiselwa emzimbeni ngokwemvelo, kuyilapho ingqamuzana libhujiswa unomphela. Njenganoma imuphi umuthi, kunemiphumela engemihle. Zihilela isikhathi esifushane...  <response>: I-ATX-101 iwumkhuba ongahlaseli, osebenza ehhovisi othatha imizuzu emihlanu. Isidakamizwa sifakwa nge-grid yamachashazi amancane lapho inani elikhulu lamafutha ngaphansi kwesilevu likhona. Iziguli ziphola ezinsukwini ezingu-2-3 futhi zingahamba ngaphandle kokugqoka ibhandeshi. Umuthi ubulala ulwelwesi lwamangqamuzana amafutha, uwenze aqhekeke futhi anyamalale unomphela. Imiphumela engemihle ihlanganisa ukuvuvukala okwesikhashana, ukulimala nokungazweli. Umuthi manje usudinga nje ukuvunywa kokugcina yi-FDA. 