<prompt> I-Aspirin ikhombisile ukuthi inezindlela ezintathu ezengeziwe zokusebenza. Ikhipha i-oxidative phosphorylation kuma-cartilaginous ne-hepatic mitochondria, ngokuhlakazeka kusuka esikhaleni sangaphakathi se-membrane njengomthwali we-proton emuva ku-mitochondrial matrix, lapho i-ionizes futhi ukukhulula ama-proton. I-Aspirin i-buffers futhi ithutha ama-proton. Lapho kunikezwa imithamo ephezulu, empeleni ingadala umkhuhlane, ngenxa yokushisa okukhishwe kusuka ku-electron transport chain, ngokungafani nomsebenzi we-antipyretic we-aspirin obonwe ngemithamo ephansi. Ngaphezu kwalokho, i-aspirin ibangela ukwakheka kwama-NO-radicals emzimbeni, okuye kwaboniswa kumagundane ukuthi abe nenqubo ezimele yokunciphisa ukuvuvuka. Lokhu kuncishiswa kwe-leukocyte kuyisinyathelo esibalulekile ekuphenduleni komzimba ekungeneni kokutheleleka; ubufakazi obanele bokuthi i-N-Bacid i-Bacid iphinde isebenze njengendlela yok  <response>: inhlanganisela ye-transcription factor 