 Nyorai kuenderera mberi kwechikamu chino - Romo akaita zvakanaka kwazvo kutanga mwaka wa2012 uye haana kubvumidza kumhanya kwakawanikwa kusvika Chivabvu 17, 2012. Pashure pokunge Brian Wilson aitwa oparesheni yaTommy John muna April, Santiago Casilla akapiwa basa rokurinda. Casilla akashandura 20 yemikana yake yekutanga 21 yekuchengetedza asi akapotsa mashanu emamiriro ake mapfumbamwe ekuchengetedza, achinyora 7.71 ERA kubva munaJune 23 kusvika Nyamavhuvhu 7. Bochy akazivisa musi waAugust 7 kuti maGiants aizoshandisa nzira ye bullpen nekomiti, naRomo, Javier López, naJeremy Affeldt vachikanda maini maviri ekupedzisira emitambo yakaoma, zvichienderana nekuti ndevapi vanorova vaizotarisana navo. Romo naLópez vakagamuchira mikana yakawanda yekuponesa; Affeldt aingova nekuponesa kamwe chete mushure meizvozvo. Kubvira ipapo kusvika pakupera kwemwaka, Romo akashandura mapfumbamwe kubva pamapfumbamwe ekuchengetedza mikana uye akaisa 1.33 ERA. Romo akaonekwa mumitambo 69 yemwaka wa2012, achiwana 14 kuchengetedza ne1.79 ERA, yaive yechina pakati peNL relievers uye yakatevera chete Craig Kimbrel 1.01, Aroldis Chapman 1.51 naEric OFlaherty 1.73. Kunyange zvazvo akanga ava pedyo nekuguma kwegore, akakunda Gibby Award nokuda kwekuva MLBs Setup Man of the Year. MaGiants akakunda NL West; muNLDS vachipesana neCincinnati Reds, Romo akaonekwa mumitambo mitatu, achikunda Mutambo 3 uye achiponesa Mutambo 5. Akaisa mune zvese zvina zveGiants kukunda muNLCS kurwisa St. Louis Cardinals asi haana kuwana mukana mumwe chete wekuponesa. Zvisinei, muWorld Seriesvachirwa neDetroit Tigers, akaita mitambo mitatu uye akarekodha kuponesa mune imwe neimwe yadzo. Akakanda inning yekupedzisira yeGame 4 uye akarova matatu akateedzana, kusanganisira Miguel Cabrera yekupedzisira kubuda uye kukunda kweGiants. MuWorld Series, Romo akaisa innings nhatu dzakakwana uye akanga ane strikeouts shanu. 