 On 11 August 2012, Buffon akasimudza mukombe wake wekutanga semutungamiriri mutsva weJuventus, zvichitevera kubuda kwaAlessandro Del Piero sezvo Juventus yakakunda Napoli 42 munguva yekuwedzera mu2012 Supercoppa Italiana muBeijing. Buffon akatambura kukuvara kuduku uye akarasikirwa nemutambo wokutanga weSerie A wemwaka wa2012 13kurwisa Parma musi wa25 Nyamavhuvhu 2012. Akadzokera kunotanga mutsara wemutambo unotevera neUdinese muUdine musi wa2 Gunyana, akapfeka kaputeni armband; Juventus yakakunda mutambo 41. Musi wa 20 Gunyana, mumutambo wekutanga weJuventus weChampions League wemwaka uyu vachipesana nevakadzi vanodzivirira Chelsea, Buffon akaita mutambo wake wechi400 weJuventus; mutambo wakapera mukukwikwidza 2 × 2 kure. Buffon akawana rake rekutanga rakachena mwaka mumutambo we2-0 kumba kukunda Chievo musi wa22 Gunyana. 