 Aquilani akatanga basa rake nechikwata cheItaly cheRoma uye, mushure mekukweretesa kwenguva pfupi kuTriestina, akadzokera kukirabhu yeSerie A kwaakava wenguva dzose muchikwata cheRoma mumwaka wa2005-06., akawana zita remadunhurirwa rekuti Il Principino Muchinda Mudiki, nekuda kwekufanana kwake neyaimbove ngano yeRoma Giuseppe Giannini, zvese maererano nechitarisiko uye maitiro ekutamba, aizivikanwa sa Il Principe Muchinda. Mumwaka unotevera, akakuvara muhudyu uye akarambwa kwemwedzi inoverengeka. Muna 2007 na2008 akahwina Coppa Italia mazita akateedzana neRoma, pamwe ne2007 Supercoppa Italiana. 