 Nyorai mashoko okuenderera mberi endima iyi - Muna March 1536, Calvin akabudisa bhuku rake rokutanga rinonzi Institutio Christianae Religionis kana kuti Institutions of the Christian Religion. Basa racho rakanga riri apologia kana kuti dziviriro yokutenda kwake uye chirevo chechimiro chedzidziso chavagadziri. Aidawo kuti rive bhuku rokutanga rokudzidzisa munhu wose anofarira kutenda kwechiKristu. Bhuku racho rakanga riri kutaura kwokutanga kwouMwari hwake. Calvin akavandudza basa racho uye akabudisa shanduro itsva muupenyu hwake hwose. Achangobudiswa, akabva muBasel achienda kuFerrara, kuItaly, kwaakamboshanda kwenguva pfupi ari munyori waMambokadzi Renée wokuFrance. Pakazosvika June akanga adzokera kuParis nomunununa wake Antoine, uyo akanga achigadzirisa nhau dzababa vavo. Pashure peMurayiro weCoucy, uyo wakapa nguva yemwedzi mitanhatu yokuti vakatsauka pakutenda vawirirane nokutenda kwechiKaturike, Calvin akasarudza kuti akanga asina remangwana muFrance. Muna August akaenda kuStrasbourg, guta raiva nesimba muUmambo Hutsvene hweRoma uye raiva nzvimbo yaipotera vanhu vaida kuchinja zvinhu. Nemhaka yokurovedza mauto ehurumende nemauto eFrance, akamanikidzwa kuita nzira yokurega kuenda kumaodzanyemba, achimuunza kuGeneva. Calvin akanga aronga kungogara usiku humwe chete, asi William Farel, mumwewo muFrance aiedza kuchinja zvinhu uyo aigara muguta racho, akamuteterera kuti agare uye amubatsire mubasa rake rokugadzirisa chechi ikoko. Calvin akabvuma basa rake idzva pasina zvaaida kuti aite. Hazvizivikanwi kuti pakutanga akapiwa basa rei. Akazopiwa zita rokuti muverengi, zvichida raireva kuti aigona kupa hurukuro dzinotsanangura Bhaibheri. Pane imwe nguva muna 1537 akasarudzwa kuti ave mufundisi kunyange zvazvo asina kumboitwa mufundisi. Kwenguva yokutanga, gweta-nyanzvi yezvechitendero rakatora mabasa oufundisi akadai sorubhapatidzo, michato, uye minamato yechechi. 