 Macri akachinja maonero eArgentina panyaya dzehondo dziri kuMiddle East. Mukati mevhiki yokutanga yaMacri ari muhofisi, akaramba chibvumirano chekunzwisisa pakati peArgentina neIran, icho chaizodai chakagadzira kuongorora kwakabatana kwebhomba ra1994 AMIA, kurwiswa kwegandanga kwesangano rechiJudha uko Argentina yakanga yapomera Hezbollah neIran. Memorandamu yacho yakanga yatongwa kuva isingabvumirwi nomutemo nedare redzimhosva, chisarudzo chakakwikwidzwa panguva youtungamiri hwaKirchner. Macri akabvisa chikumbiro chacho, achitsigira mutongo wokutanga. Akazviparadzanisa neIran uye akakurudzira kuenderera mberi kwekuferefetwa kwe AMIA kuputika uye kufa kwaAlberto Nisman, muchuchisi aiongorora nyaya iyi. Mhosva idzodzo uye kuferefeta kwaNisman pamusoro pekubatanidzwa kwaCristina Kirchner neIran zvine kukosha kwakakosha kuArgentina-Israel hukama, uye mumiriri Carlos Faustino García nemumiriri weIsrael Modi Efraim vakarumbidza Macri nekukurudzira kuferefeta. Macri akavandudza hukama neIsrael uye munaGunyana 2017, Mutungamiriri weNyika Benjamin Netanyahu akazova Mutungamiriri weIsrael wekutanga kushanyira Argentina. Muna Chikunguru 2016, zvakaziviswa kuti Argentina yaizopa hupoteri kune vapoteri ve3,000 veHondo Yenyika yeSyria. Muna Chikunguru 2019, Macri akarondedzera Hezbollah sesangano remagandanga zvine chekuita nekuputika kwemumiriri weIsrael, uye kunyanya zvine chekuita nekuputika kweAMIA. 