 Seedorf akaita basa guru sezvo Milan akasvika Champions League yokupedzisira zvakare muna 2005, scoring chete chinangwa mutambo wavo rokutanga boka mutambo pamusoro Shakhtar Donetsk musi 14 September 2004 uye kuoneka zvose 13 makwikwi machisi. Akatanga mutambo neLiverpool muIstanbul umo Milan yakarasikirwa ne3-0 inotungamira, pakupedzisira ichirasikirwa nezvirango mushure mekuita 3-3; Seedorf haana kutora chirango. Milan yakapedzawo iri runners-up muSerie A, mapoinzi manomwe kumashure kwemakwikwi eJuventus, kunyangwe Juventus yakabviswa zita uye Milan yakaisa mapoinzi ekuronga mitambo. 