 I-122, yakagadzwa muna 1925 seSubmarine No. 49 uye inozivikanwa seI-22 kubva panguva yekuvakwa kwayo kusvika munaJune 1938, yaive yeImperial Japanese Navy yakashanda panguva yeChipiri Sino-Japanese Hondo uye Hondo Yenyika II. Munguva yekurwisana kwekupedzisira, akaitisa mabasa ekutsigira kupindirwa kweJapan kweMalaya, kupindirwa kweJapan kwePhilippines, kubhombwa kweDarwin, Hondo yeMidway, hondo yeGuadalcanal, Hondo yeEastern Solomons, uye hondo yeNew Guinea. Yakanyura muna 1945. 