 Maererano neChibvumirano cheNagyvárad, John Zápolya aifanira kuteverwa naArchduke Ferdinand weAustria, asi vakuru vakuru veHungary, kunyanya Bhishopu George Martinuzzi, vakaramba kutevedzera uye muna September 1540 vakasarudza mwana John Sigismund saMambo weHungary naIsabella semutongi wake. Ferdinand akapinda muHungary ndokukomba Buda uko Isabella nomwanakomana wake vakatsvaka utiziro. Guta racho rakakunda pakakombwa kokutanga muna November 1540 uye pakakombwa kechipiri muna May 1541rakasimudzwa naSuleiman Mukuru, Sultan weOttoman Empire. Haana kugamuchira betsero kubva kuna baba vake Sigismund I Mukuru. Suleiman akasarudza Hungary yakakamurwa asi akanzwisisa kuti iye bedzi ndiye aigona kuidzivirira kubva kuvaHabsburg. Nokudaro, akachinja zvakawanda zveHungary kuva pashaliks purovhinzi yaitongwa napasha uye Transylvania chete nenyika dziri kumabvazuva kweRwizi Tisza inozivikanwa seTemesköz zvakapiwa John Sigismund naIsabella somuchengeti wake. Kugadzwa uku kwakagamuchirwa neTransylvanian Diet ichibvuma chinzvimbo chayo semuridzi weOttoman Empire. 