 Nyorai kuenderera mberi kweiyi ndima - Kimbrel akawana kudanwa kwake kwekutanga kubva kuGwinnett Braves musi waMay 15, 2010, kuti atsive Jair Jurrjens akakuvara pachikwata. Akashevedzwa kechipiri mubasa rake musi waJune 4, 2010, kuti atsive Takashi Saito, uyo akaiswa paDL kwemazuva gumi nemashanu. Akawana yake yekutanga Major League kuchengetedza musi waGunyana 19, 2010 vachipesana neNew York Mets. Kimbrels rekodhi ye2010 mwaka yaive 40, ine imwechete inochengetedza uye 0.44 ERA mumainnings. Akanyora 40 strikeouts uye 16 kufamba. Muna 2010 NLDS, ndiye akanga ari mutambi akarasikirwa muGame 3 achipesana neWorld Series ChampionSan Francisco Giants. 