 Nyorera kuenderera kweiyi ndima - Munguva yemwaka wa2013 14, Marchisio ainyanya kukwikwidza neFrance mudiki Paul Pogba yenzvimbo pakati penzvimbo nhatu. Akatambura nekukuvara kwakagadziriswa panguva yekirabhu 2013 Supercoppa Italianakukunda, uye yainyanya kushandiswa sechinotsiva mukati mehafu yekutanga yemwaka panguva yemitambo yeligi, kutanga mumitambo yeChampions League Europa League pachinzvimbo. Chikamu nekuda kwekushayikwa kwaArturo Vidal nekuda kwekuvhiyiwa kwebvi, Marchisio akatanga mimwe mitambo mumwedzi mishoma yekupedzisira yemwaka zvibodzwa zvake zvina zvese zvakauya mukati mehafu yekupedzisira yemwaka. Muna Kubvumbi achipesana neBologna akaita basa rake 200th Serie A kuoneka. Akawana chinangwa chekupedzisira cheJuve chemwaka uyu pazuva rekupedzisira remutambo wemwaka, kukunda 3-0 pamusoro peCagliari. Juventus akakwanisa kukunda mukombe wavo wechitatu mumutsara mwaka iwoyo, uye yavo yechi30 yakazara, ine rekodhi yeItaly yemapoinzi 102. Juventus yakabviswa muchikamu cheboka reChampions League, zvisinei, kunyange zvazvo vakakwanisa kusvika kuma semi-fainari eEuropa League, kwavakakundwa naBenfica. 