 Ramba uchinyora ndima iyi - Hondo dzeItaly dzaive dzakatevedzana dzehondo kubva muna 1494 kusvika muna 1559 dzakabatanidza, panguva dzakasiyana-siyana, mazhinji emaguta-nyika eItaly, Nyika dzePapa, Republic yeVenice, uye gare gare mazhinji emarudzi makuru eWestern Europe. Mutongi akazvimirira wokupedzisira weMilan, Lodovico il Moro, akadana mambo weFrance Charles VIII kuItaly achikarira kuti France ingava mubatanidzwa muhondo dzomukati meItaly. Mambo womunguva yemberi weFrance, Louis weOrléans, akabatanidzwa murwendo rwacho ndokuziva kuti Italy yakanga isina kudzivirirwa chaizvoizvo. Ikoku kwakamusunda kudzoka makore mashomanene gare garemuna 1500, uye anozviti ndiye Duchy weMilan, sezvo ambuya vake vakanga vari nhengo yemhuri yaVisconti yaitonga. Panguva iyoyo, Milan yaidzivirirwawo nemauto eSwitzerland. Pashure pokukunda kwaFrançois I, mutsivi waLouis, pamusoro pevaSwitzerland paHondo yeMarignan, duchy yakapikirwa kuna mambo weFrance François I. Apo Mambo weSpain weHabsburg Charles V akakunda François I paHondo yePavia muna 1525, kuchamhembe kweItaly, kusanganisira Milan, yakapinda muHabsburg Spain. 