 Nyorera kupfuurira kweiyi ndima - Mumakore e1980 uye kutanga kwe1990 Prost akaumba kukwikwidzana kwakasimba kwemitambo, kunyanya naAyrton Senna asiwo Nelson Piquet naNigel Mansell. Muna 1986, muAdelaide munhangemutange yekupedzisira yemwaka, akarova Mansell naPicquet veWilliams kuhwina mukombe, mushure mekunge Mansell aenda pamudyandigere munhangemutange uye Piquet akadhirowewa kunonoka kwekuchengetedza. Senna akabatana naProst paMcLaren muna 1988 uye vaviri vacho vakava nemakakatanwa akawanda, kusanganisira kurwisana pa1989 Japanese Grand Prixizvo zvakapa Prost mukombe wake wechitatu weDrivers Championship. Gore rakatevera panzvimbo imwe cheteyo, vakarwisanazve, asi panguva ino Prost, achityaira Ferrari, akarasikirwa. Pamberi pokuguma kwemwaka wa1991 usina kukunda Prost akadzingwa neFerrari nokuda kwekutsoropodza kwake pachena kwechikwata. Mushure mokunge apedza basa muna 1992, akabatana neboka reWilliams, achikurudzira Mansell, Mutungamiri weVatyairi, kuti aende kuCART. Nemotokari yemakwikwi, Prost akakunda mukwikwidzi wa1993 uye akasiya basa kubva kuFormula One kutyaira pakupera kwegore. 