 Ramba uchinyora ndima ino - Dunhu rePanama raiva chikamu cheumambo hweSpain panguva yehondo dzekuzvimiririra kubva kuSpain. Pashure pokukunda kworudzi muhondo yeCarabobo, vanhu vokuPanama vakasarudza kubatana neGran Colombia. Kusvikira panguva ino, Panama yakanga yakaramba iri pasi poumambo hweSpain uye yakanga yanzvenga zvinetso zvaitambudza humwe umambo hweNew Granada. Pana November 28, 1821 Panama yakabatanidzwa nokuzvidira kuGran Colombia pasi peBumbiro reCúcuta, rakanga raziviswa pana August 30, 1819. 