 Fred Duesenberg akagadzirawo injini dzeDuesenberg dzemotokari dzomumhanyi dzakakunda mijaho mitatu yemakiromita 500 yeIndianapolis: mujaho wa1924nemutyairi Lora L. Corum uye mutyairi anotsiva Joe Boyer; mujaho wa1925 nemutyairi Pete DePaolo uye mutyairi anotsiva Norman Batten; uye mujaho wa1927 naGeorge Sanders mumotokari yakavakwa naDuesenberg yaive yaBill White. Muna 1925 motokari yemakwikwi yeDuesenberg naPete DePaolo semutyairi yakava mukundi wokutanga weIndianapolis 500-maira ane avhareji inopfuura. Muna 1926 DePaulo akapedza ari pachinzvimbo chechishanu mumakwikwi akapfupikiswa nemvura, nepo imwe mota yechikwata cheDuesenberg yaityairwa nemutyairi mutsva Ben Jones akasangana nematambudziko emuchina uye akadonha pamberi pekupera kwemakwikwi. Chikwata chaDuesenberg chakaramba chichiiswa pakati pezvikwata gumi zvepamusoro mumakwikwi emakiromita 500 eIndianapolis muna 1928 na1929. Mumakwikwi a1928, Fred Frame akatyaira mujaho weDuesenberg kusvika kunzvimbo yechisere, nepo Jimmy Gleason akatyaira mota yechikwata cheDuesenberg kusvika kunzvimbo yegumi neshanu. Munhangemutange ya1929 migumisiro yechikwata yakavandudzwa naGleason achitora nzvimbo yechitatu uye Freddy Winnai achipedza nzvimbo yechishanu. 