 Nyora kupfuurira kweiyi ndima - Muna 2004, Menounos akaonekwa muchikamu cheUPN nhepfenyuro One on One saGlenda, eccentric, akazviti Fairy Godmother kune Nyeredzi. Muzhizha ra2005, akaonekwa mufirimu yemabhuku enyambo Fantastic Four, kwaakatamba mukoti uyo anodanana neHuman Torch, inoridzwa naChris Evans. Kufanana kwake uye inzwi rakaratidzwa mu2005 Electronic Arts vhidhiyo mutambo James Bond 007: Kubva kuRussia nerudo saEva Adara, mukadzi weRed Grant, uyo nyeredzi Sean Connery saJames Bond. Ndiyewo mutauriri wezvigadzirwa zvebvudzi zvePantene. VaMenounos vakapa hurukuro yavo ya2006Eurovision Song Contest pamwe nomuimbi wechiGiriki Sakis Rouvas yakaitika muAthens. Menounos akarongawo Muteereri Wenguva refu naWilmer Valderrama. Iyi firimu yaive sarudzo yepamutemo yeTribeca Film Festival 2006. Menounos akaita uye akagadzira Adventures of Serial Buddies, iyo inonzi ndiyo yekutanga serial mhondi buddy comedy. 