 Nyora kuenderera kweiyi ndima - Musi wa21 Gunyana 2016, De Ligt akaita mutambo wake wekutanga kuchikwata chevakuru cheAjax mumutambo wekombe uchipesana naWillem II. Akahwina kubva pakona mushure memaminitsi makumi maviri nemashanu, achimuita wechipiri-mudiki-wechidiki zvibodzwa zvachose mushure meClarence Seedorf. Musi wa 24 Chivabvu, akazove mutambi mudiki pane vese 17 makore nemazuva 285 kutamba mumakwikwi makuru eEuropean paakatanga kurwisa Manchester United mu2017 UEFA Europa League Final. Musi wa17 Zvita 2018, De Ligt akahwina mubairo weGolden Boy, achiva mudziviriri wekutanga kuhwina mubairo. Mwaka wakatevera, akabatsira Ajax kutora kaviri mudzimba uye kusvika kuma semi-fainari eChampions League; kuita kwake kwakamuwanisa kuenda kuSerie A divi Juventus, uye akamuona achikunda Kopa Trophy muna 2019. Akakunda mukombe weSerie A mumwaka wake wekutanga nechikwata cheTurin. 