 Nyora kupfuurira kweiyi ndima - Kupinda kwaTimur muGeorgiapakati pa 1386 na 1403 akaunza kupera kwenguva yakaisvonaka yaDmanisi. Muna 1486, guta rakaparadzwa pakurwiswa naYaqub bin Uzun Hasan, mutongi weAq Qoyunlu. Mushure mekuparara kwekupedzisira kwehumambo hweGeorgia muma1490, yakava chikamu chehumambo hweKartli. Dmanisi akabva apiwa korona kumhuri yeBaratashvili, iyo mitsara miviri yakakamura guta rose nenzvimbo dzaro muna 1536. Dmanisi yakatorwa ndokusimbiswazve nemauto eOttoman muna 1578, asi yakadzorerwa naMambo Simon I weKartli muna 1583. Pashure pacho, Dmanisi rakanga risingori nzvimbo yavarwi yaiva yevaBaratashvili. Kuvandudzwa kwezvoupfumi uye zvechechi muDmanisi, panguva iyoyo yainziwo Dbanisi, pakutanga kwezana remakore rechi18, kwakaratidza kuva kwenguva pfupi. Kudonha kwaDmanisi muhondo yakadzokororwa uye kusarongeka kwezvematongerwo enyika kwakateverwa nekuparadzwa kwebhishopu wayo kuona pakati pezana ramakore rechi18; nzvimbo iyi yakave isina vanhu kusvika pekugara misha yekumaruwa yakatanga kubuda kutenderedza guta rekare raive pasi pehutongi hweRussia hweGeorgia mukutanga kwezana ramakore rechi19. Imwe yadzo, Bashkicheti, yakatumidzwa kuti Dmanisi pashure peguta renhau muna 1947. 