 Nyorai kuenderera mberi kweiyi ndima - Muna 334 BC akapinda muAchaemenid Empire Persian Empire ndokutanga nhevedzano yemisangano yakatora makore gumi. Pashure pokukunda kwake Asia Minor Turkey yazvino uno, Alexander akaparadza simba rePersia munhevedzano yehondo dzinosarudza, kubatanidza idzo paIssus neGaugamela. Iye gare gare akakoromora Mambo Dhariusi III ndokukunda Umambo hwaAchaemenid hwose. Panguva iyoyo, umambo hwake hwaitangira kuGungwa reAdriatic kusvika kuRwizi rweIndus. Alexander akaedza kusvika kumigumo yenyika neGungwa Guru Rokunze uye akapinda muIndia muna 326 BC, achiwana kukunda kunokosha pana Mambo Porus paHondo yeHydaspes. Pakupedzisira akadzokera kuRwizi rweBeas nekuda kwekuda kwemauto ake aisuwa kumusha, akafira muBhabhironi muna 323 BC; guta raakaronga kuti rive guta rake guru. Haana kukwanisa kuita nhevedzano yemishandirapamwe yakarongwa iyo ingadai yakatanga nokupinda muArabia. Mumakore akatevera rufu rwake, hondo dzomunyika dzakawanda dzakaparadza umambo hwake. 