 Ramba uchiverenga ndima ino - Kubva munenge muna 1450, masimba makuru matatu ezvikepe akaumba kutonga pamusoro penzvimbo dzakasiyana-siyana dzeMediterranean achishandisa magareya sezvombo zvavo zvikuru mugungwa: vaOttoman kumabvazuva, Venice pakati uye Habsburg Spain kumadokero. Musimboti wengarava dzavo wakanga wakabatanidzwa muzvitsigiro zvengarava zvitatu zvikuru, zvaivimbwa nazvo zvizere muMediterranean: Constantinople, Venice, uye Barcelona. Hondo dzomugungwa muzana ramakore rechi 16 muMediterranean dzainyanya kurwiwa pamwero muduku, nekupamba uye zviito zviduku zvainyanya. Hondo nhatu bedzi dzezvikepe zvikuru chaizvoizvo dzakarwiwa muzana ramakore rechi 16: hondo dzePreveza muna 1538, Djerba muna 1560, uye Lepantomuna 1571. Lepanto yakava hondo huru yokupedzisira yezvikepe zvose, uye yakanga iriwo imwe yehondo huru zvikuru maererano nevatori vechikamu chero kupi zvako muEurope yemazuva ano yepakutanga pamberi peNapoleonic Wars. 