 Rossi akaenderera mberi semutyairi wekuchengetedza mu2015 yeManor Marussia F1 Team ichangobva kuumbwa. Iye pakupedzisira akaita kutanga kwake paSingapore Grand Prix. Rossi akasarudza No. 53 sezvo basa rake motokari nhamba kukudza Herbie; sarudzo yake yepakutanga yaiva No. 16, iyo akashandisa mubasa rake Karting, asi nhamba akanga atova vaizviti sezvo inochengeterwa nhamba ne Red Bull Racing. Rossi akakwanisa 20 uye wokupedzisira nokuda debut yake, asi rallied kupedza 14th, chete mberi chikwata naye Will Stevens 15th, pasinei nokurasikirwa redhiyo kutaurirana pamwe chikwata chake kumativi nechepakati pfungwa Grand Prix. Rossi aizopinda mumakwikwi mashanu pamakwikwi manomwe ekupedzisira emwaka wa2015. MuJapan Grand Prix, Rossi akapedza ari wechi18, zvakare nzvimbo imwe pamusoro paStevens. Aizoenderera mberi kuenzana neManor Marussias yakanakisa mhedzisiro yemwaka kumakwikwi ake epamba, United States Grand Prix, achipedza gumi nemaviri, uye achiva mutyairi wekutanga weAmerica kumhanya munzira yakavakirwa chinangwa cheFormula One muUnited States. Rossi akabva atora 15th paMexico Grand Prix asati apedza makwikwi ake mashanu paBrazil Grand Prix aine 19th nzvimbo yekupedzisira. 