 Nyorai mberi kweiyi ndima - OKeefe akava mutariri weNASA pana December 21, 2001 pashure pokunge Seneti yeUnited States yasimbisa kugadzwa kwake. Akauya kuNASA asina kudzidziswa zvesayenzi kana zveinjiniya sezvakaitika kuna James E. Webb uyo aiva mutariri weNASA kubva muna 1961 kusvika muna 1968. Nguva yaOKeefe paNASA inogona kukamurwa kuva nhambo nhatu dzakaenzana, imwe neimwe yakaratidzirwa nechinetso chimwe chete kana kuti chiitiko chinokosha zvikuru. Munguva yaDecember 2001 kusvika kuna January 2003, OKeefe akabvisa mari inodarika mabhiriyoni mashanu emadhora pakuvaka International Space Station. Muna 2003, akabata nenjodzi yeColumbianemigumisiro yacho. Kubva muna Ndira 2004 kusvika muna Kukadzi 2005, OKeefe akarongazve NASA kuti itange kushanda paPurezidhendi George W. Bush achangobva kuzivisa Chiono cheKutsvaga Kwemuchadenga kutumira vanhu kuMwedzi neMars. 