 Nyorai kupfuurira kweiyi ndima - France yakanga ichitora nzvimbo yeItaly senzvimbo yokunamatira mabhuku ounyanzvi mukati mezana ramakore rechigumi namatanhatu. Kuchinja kwezvematongerwe enyika muItaly, Kupambwa kweRoma muna 1527, uye kubatwa kweMilan neFrancekwakanga kwaita kuti zvinhu zvitsva zvakadai sokushandisa zvishandiso zvendarama zvisvike kuFrance, uko zvakakurumidza kugamuchirwa nokuvandudzwa. Chibvumirano cheFrance neOttoman chakaunza matehwe emhando yepamusoro eMorocco uye kuwanda kwevagadziri vane unyanzvi zvikuru. Vanhu vokuFrance vaibatanidza mabhuku vakatanga kugadzira mabhuku akafukidzwa negoridhe muna 1507. Pakazosvika 1535, vakanga vava kukwanisa kuzvigadzira pamwero mukuru zvichiratidza kuisvonaka kwokuzadza, runako rwokugadzira uye unyanzvi hwokuzviita. 