 Ramba uchinyora ndima iyi - Muna August 1938, Sergei akasangana naMira Mendelson, mudzidzi wemabhuku ane makore 23 aiva mudetembi uye mushanduri. Vose vakanga vari pazororo muKislovodsk nemhuri dzavo. Chakanga chatanga somubatanidzwa webasa nokukurumidza chakava ukama hwevatano. Kunyange zvazvo Sergei pakutanga akanga asina hanya naMira kuna Lina, mumwedzi mishomanana akamuzivisa ukuru hweukama hwake hutsva. Lina akapindura kuti akanga asingapikisani nazvo chero bedzi iye asina kuenda kunogara naye, iye akayeuka mubvunzurudzo makumi amakore gare gare. Muchato wavo wakaramba uchipera simba; musi wa 15 March 1942, Sergei akazivisa kuti aizogara naMira, achigumisa muchato wake naLina. Mwedzi mishomanene gare gare apo kurwisa kweGermany Russia kwakatyisidzira Moscow, Prokofiev akaedza kunyengetedza Lina nevanakomana vavo kuti vaende naye sevakadzingwa muguta guru, asi Lina akaramba. Pashure pokuguma kweHondo Yenyika II, Sergei akaedza kupa Lina magwaro okurambana nomwanakomana wavo Oleg, uyo asina kuita basa racho nokuda kwegarikano yaamai vake. Sergei ipapo akakumbira kurambana mudare musi wa22 November 1947. Mazuva mashanu gare gare, dare rakazivisa kuti rakanga raramba chikumbiro chake nemhaka yokuti roorano yacho yakanga isiri yechokwadi pakutanga nemhaka yokuti yakanga yaitwa kunze kwenyika uye yakanga isina kunyoreswa zvakakodzera nezviremera zveSoviet. Pashure pokunge dare rechipiri rakatsigira mutongo wacho, Sergei neshamwari yake Mira vakaroorana musi wa13 January 1948. 