 Nyorai kupfuurira kweiyi ndima - Appleton akaroora Sarah Newcomb Allen, hanzvadzi yomukwanyina wake panguva iyoyo mumutemo uye aizova congressman, Elisha Hunt Allen, muna 1834. Aiva nevana vashanu, John, Frederic, Sarah, Henry, naEdward. Mukuru wake, ainziwo John, akanga ari Brigadier General muUnion Army uyo akatungamirira boka guru revarume paKukombwa kwePort Hudson. Sarah akafa pana 12 August 1874. Appleton akaroorazve pasi pemakore maviri gare gare kuna Annie V. Greeley musi wa 30 March 1876. Annie naJohn vakanga vasina vana vanozivikanwa. Appleton aiva nhengo yeChechi yeUnitarian. 