 Nyorai mberi kweiyi ndima - Henderson akabatana neSunderland Academy pazera remakore masere, achiita kutanga kwake kwekutanga-timu makore gumi gare gare munaNovember 2008. Akapedza mwedzi mitanhatu pachikwereti kuCoventry City mu2009, asati adzokera kuSunderland. Muna 2011, Henderson akasainira Liverpool, achikunda mukombe wake wekutanga nekirabhu, iyo League Cup, gore rakatevera. Akagadzwa kaputeni weLiverpool muna 2015, Henderson akakunda UEFA Champions League, UEFA Super Cup uye FIFA Club World Cup muna 2019, uye muna 2020 akatungamira timu yake kuhwina mukombe wePremier League, mukombe wokutanga wenhabvu wechikwata chacho mumakore 30. Nokuda kwemitambo yake mumutambo wokukunda mwaka, Henderson akatumidzwa kuti FWA Footballer of the Year. 