 Nyorai kupfuurira kweiyi ndima - Apo Simón Bolívar akatora hutungamiri hwePeru February 17, 1824, Santa Cruz akabatana neuto rake uye akatumidzwa kuti Chief of Staff wePeruvian Division. Ari mumamiriro ezvinhu akadaro, akapinda muHondo yeJuninAugust 6, 1824. Pashure pacho, akatumidzwa zita rokuti Prefect weAyacucho, uye ipapo Mukuru weVashandi vePatriot Army munguva yekurwira kusunungurwa kweBolivia. Somubayiro wezviito zvake, Santa Cruz akagamuchira mazita aMarchal uye Prefect weChuquisaca muna April 1825. 