 Nyorai mberi kweiyi ndima - Nokuda kwehondo yake yechipfumbamwe, I-162 yakashandiswa kutsigira Operation Kekubviswa kweGuadalcanal sezvo hondo yeGuadalcanal yakapera mukukundwa kweJapan nokuita mabasa okutsausa kubva kumhenderekedzo yokuchamhembe kwakadziva kumadokero kweAustralia. Achibva kuSurabaya musi wa26 Ndira 1943, akaongorora Cocos Island mukupera kwaNdira 1943. Musi wa14 February 1943, United States Navy submarine yakarwisa ngarava yacho kuLesser Sunda Islands kumabvazuva kweThwartway Island pa. Thresher akapfura zvikepe zviviri zveMark 14 torpedoes, chimwe chazvo chakatadza kuputika, nepo chimwe chakakundikana ndokuputika pasina kukuvadza I-162. I-162 yakazarura moto paThresher nepfuti dzayo dzomubato, yakatendeukira kuchamhembe, ndokupukunyuka isina kukuvadzwa. Akadzokera kuSurabaya musi wa16 Kukadzi 1943. 