 Ramba uchiverenga ndima iyi - Ishe Robert Cecil vakatanga kusarudzwa kuHouse of Commons muna 1854 uye vakashanda saGurukota reHurumende yeIndia muhurumende yaIshe Derby yeConservative muna 1866-1867. Muna 1874, pasi paDisraeli, Salisbury akadzoka saMunyori weHurumende weIndia, uye, muna 1878, akagadzwa kuva munyori wezvekunze, uye akaita basa rinotungamira muCongress yeBerlin. Mushure mekufa kwaDisraeli muna 1881, Salisbury akabuda semutungamiri weConservative muImba yeMakurukota, naSir Stafford Northcote vachitungamira bato muCommons. Akatsiva William Ewart Gladstone semutungamiriri wehurumende muna Chikumi 1885, uye akabata hofisi kusvika muna Ndira 1886. Apo Gladstone akabuda achitsigira Kutonga Kwemusha kweIreland, Salisbury akamushora ndokuumba mubatanidzwa nevapanduki veLiberal Unionists, vachikunda sarudzo dzakazotevera. Kubudirira kwake kukuru munguva iyi kwaiva kuwana nzvimbo dzakawanda itsva muAfrica munguva yeCrush for Africa, kudzivisa hondo kana kusangana kwakakomba nemamwe masimba. Akaramba ari mutungamiriri wehurumende kusvikira maLiberals aGladstone aumba hurumende nokutsigirwa nevaIrish nationalists musarudzo huru ya 1892. VaLiberals, zvisinei, vakarasikirwa nesarudzo huru ya 1895, uye Salisbury kwenguva yechitatu uye yokupedzisira akava mutungamiriri wehurumende. Akatungamirira Britain kukunda muhondo inotyisa, ine gakava navaBoer, uye akatungamirira Unionists kukundazve musarudzo muna 1900. Akasiya chinzvimbo chaPrime Minister achichipa muzukuru wake Arthur Balfour muna 1902 uye akafa muna 1903. Akanga ari mutungamiriri wehurumende wokupedzisira kubatira kubva kuImba yaMadzishe. 