 Irene Asanina akafa mushure me1354, aive Empress consort waJohn VI Kantakouzenos weByzantine Empire. Iye anozivikanwa kuva akapinda munyaya dzechiuto kusvika padanho risingawanzoitika kumambokadzi weByzantine. Akatungamira varwi veDidimotekicho panguva yehondo yevagari vemuByzantium ya13411347., uye akaronga kudzivirirwa kweConstantinople kurwisa vaGeneuse muna 1348, uye mauto aJohn V muna 1353. 