 Nyorai kupfuurira kweiyi ndima - Southampton yakapinda muPearl Harbor musi wa 26 November uye, kwemwedzi miviri yakatevera, yakabatanidzwa mumitambo yeamphibious muzvitsuwa. Yakasiya Pearl Harbor musi wa 27 Ndira 1945 nenhengo dze25th Regiment, 4th Marine Division, vakakwira. AKA yakasvika paEniwetok muMarshall Islands musi wa5 February uye, mazuva maviri gare gare, yakaenda kuSaipan. Yakasvika Saipan musi wa 11, yakaita zvidzidzo zvokupedzisira zvokupinda muTinian pakati pa 13 na 15, uye yakabva yaenda kuIwo Jima zuva rakatevera racho. Southampton yakapinda munharaunda yayo yokufambisa paIwo Jima musi waFebruary 19. Akaderedza ngarava dzokudonhedza uye akavatumira kune dzimwe ngarava dzechikamu kuti vatakure mauto ekurwisa kumahombekombe. Southampton yakatambura kurasikirwa kwayo bedzi kwokudenha Iwo Jimapakumhara kwokutanga apo bhomba rakaputika riri pedyo nechimwe chezvikepe zvaro zveLCVP ndokurova mutyairi wengarava nomufambisi wengarava. Mukati memavhiki maviri okupedzisira aFebruary, ngarava inotakura zvinhu yakabatanidzwa mukuburitsa mauto nezvokuyamura uye kutakura vanokuvadzwa kubva kunorwa pamhenderekedzo. Aya mabasa aiwanzokanganiswa nokufamba nendege dzevavengi. Musi waMarch 1, Southampton yakaenda kuMariana Islands. 