 Hornish akatanga kutyaira kweMarlboro Team Penske panguva ya2004 IndyCar Series mwaka mune yayo No. 6 Dallara IR03-Toyota Indy V8, kuhwina mwaka wekuvhura kuHomestead-Miami mumujaho wake wekutanga nechikwata, achipfuura waaitamba naye Hélio Castroneves pakupedzisira. Pashure pokuva panzvimbo yechi11 muIndianapolis 500, akarwira kutungamira naBuddy Rice naDan Wheldon uye akatungamira kumativi mapfumbamwe kumativi okutanga Hornish akatungamira mubasa rake reIndianapolis 500. Pa lap 105, achipinda mu main straightway kunze kwe turn yechina, Hornish akaedza kupfuudza Darren Manning naGreg Rays laped car. Vakakandirana, vachipinda mupit lane; Hornish akapedza ari 26th, achidonha kusvika kunzvimbo yechipfumbamwe mumapoinzi. Mamwe ose emwaka wake akanga ari pasi-par, ane mapedzero maviri epodhiyamu. Hornish akanga ari wechinomwe mumakwikwi emakwikwi nemapoinzi 387, kuguma kwake kwakashata kubva paakaisa 21 muna 2000. 