 Nyorai kuenderera mberi kweiyi ndima - Muawiya nababa vake Abu Sufyan vaipikisa Muhammad, hama yavo iri kure yeQurayshite uye gare gare mukwasha waMuawiya, kusvikira Muhammad atora Mecca muna 630. Pashure pacho, Muawiya akava mumwe wevanyori vaMuhammad. Akagadzwa naCaliph Abu Bakr mutevedzeri wemutungamiriri mukukunda kweSyria. Akakwira chinzvimbo kusvikira ava gavhuna weSiriya panguva yokutonga kwehama yake, Caliph Uthman r. Akabatana nedzinza rine simba reBanu Kalb romupurovhinzi yacho, akavaka masvingo emaguta aro ari pamhenderekedzo yegungwa uye akatungamirira hondokurwisa Umambo hweByzantium, kubatanidza hondo dzokutanga dzomumvura dzechiMuslim. Pashure pokuurawa kwaUthman muna 656, Muawiya akatora mhaka yokutsiva caliph uye akashora mutsivi wake, Ali. Munguva yeHondo Yenyika Yokutanga yevaMuslim, vaviri ava vakatungamira mauto avo kunzvimbo yakamira paHondo yeSiffin muna 657, zvichikonzera nhevedzano yekutaurirana kwekutonga kuti vagadzirise hondo. Pashure pacho, Muawiya akazozivikanwa semutongi nevatsigiri vake vokuSiriya uye mubatsiri wake Amr ibn al-As, uyo akakunda Ijipiti kubva kuna gavhuna waAli muna 658. Mushure mekuurayiwa kwaAli muna 661, Muawiya akamanikidza mwanakomana waAli uye mutsivi Hasan kuti abvise chigaro kuKufa uye kutonga kwaMuawiya kwakazivikanwa muCaliphate yese. 