 On 18 June 2012, pashure kupora kubva kukuvara kwake, Barzagli akanga akasarudzwa pamusoro Leonardo Bonucci kutamba Ireland pamwe Juventus chikwata shamwari Chiellini muItaly wokupedzisira mutambo pakati Euro 2012 boka danho. Mumutambo wake wekutanga wemutambo, akabatsira timu kuchengetedza pepa rakachena mukukunda 20 pamusoro peIreland, izvo zvakabvumira Italy kuti ikwanise kuenda kumakwikwi ekurova. Musi wa24 Chikumi 2012, Barzagli akatanga mumutambo weItaly weEuro 2012 wequarter-fainari vachipesana neEngland, izvo zvakakonzerawo kukunda kweItaly pamatare, mushure mekunge mutambo wapera 00 zvichitevera nguva yekuwedzera. Musi wa 28 Chikumi 2012, Barzagli akaenderera mberi nekubudirira kwake muEuro 2012 nekubatsira Italy mukukunda 2-1 kurwisa Germany. Italy yakazokundwa nokudzivirira Europeanuye World Champions Spain mumutambo wekupedzisira; kunyange zvazvo vakakundwa 40, nzvimbo yavo mumutambo wekupedzisira yakanyatsokodzera ivo ku2013 Confederations Cup. 