 Saitoti akapinda mune zvematongerwo enyika senhengo yeparamende yakasarudzwa uye gurukota rezvemari muna 1983, achisimuka kuti ave mutevedzeri wemutungamiri wenyika yeKenya, gurukota rezvedzidzo, kuchengetedzeka kwemukati uye hutongi hwepurovhinzi uye nyaya dzekunze. Vashoma vanomuziva se reformist, asi zvaakataura seMutungamiri weKANU Review Committee, inozivikanwa se Saitoti Committee muna 1990-91, yakavhura KANU shanduko yemukati uye yakagadzira danho rekubviswa kweChikamu 2A uye kudzoka kweKenya kudemokrasi yakawanda. Saitoti akasiya KANU ndokujoina vanopikisa, achiva munhu mukuru munhaurirano dzakatungamira ku NARC Revolution muna 2002. SeGurukota reKuchengetedzwa Kwemukati neHurumende yePurovhinzi, Mutevedzeri wegurukota rezvekunze uye nhengo yakakosha yeNational Security Advisory Committee NSAC, akazoshanda padhuze nebazi rezvekudzivirirwa kwenyika kuti aone kuburikidza neOperation Linda Nchikurwisana neboka revapanduki reAl-Shabaab. Mukuwedzera, mapoka anokwikwidzana kwemakumi emakore akanga ataura nezvokubiridzira kwakashata kwaGoldenberg kuti abvise Saitoti mune zvematongerwe enyika, asi matare edzimhosva akamubvisa mumhosva yacho muna July 2006. Nhaka mbiri yaSaitoti seMasai nenhengo dzemhuri yeKikuyu yakamuita kuti ave nemaonero epan-Kenya, asi zvakare akamuramba hwaro hwakasimba hwemadzinza kusiyana nevakwikwidzi vake. Somumwe wevatungamiriri vezvematongerwo enyika vane ruzivo rweKenya, Saitoti airondedzerwa semutambi anotungamira munhangemutange yekutsiva Mutungamiri Mwai Kibaki. 