 Ramba uchiverenga ndima ino - Mushure mekurwa kweGomo reLabus muna 209 BC, Antiochus III akapinda muHyrcania ndokutora maguta eTambrax neSyrinx, achimanikidza Arsaces II, uyo akabvumidzwa kuenderera mberi nekutonga kwake Hyrcania neParthia, kuti ave mutevedzeri weSeleucid Empire. Mukati mokukombwa kweSyrinx, apo rusvingo rwakaputswa, varwi vakauraya vagari vechiGiriki ndokuedza kutiza. Arsaces II angave akazivisazve kuzvimiririra kwake muna 189 BC, zvichitevera kukundwa kwaAntiochus nemaRoma muhondo yeMagnesiamuna 190 B.C. Munguva yekutonga kwaAntiochus IV, mukupera kwezana ramakore rechipiri BC, Hyrcania yakanga ichiri chikamu cheSeleucid Empire. Mushure mokunge Mithridates akunda Media muna 148 BC, vaHyrcanians vakatanga kupandukira kwakanga kusina kubudirira, uko kwakapwanywa naMithridates nguva pfupi pashure. Hyrcania yakashanda senzvimbo youmambo yokuzororera uye Mithridates akazorora imomo muna 141 BC. Muna 139 BC, Demetrius II akatanga kurwisa Humambo hweArsacid chete kuti akundwe uye abatwe, mushure mezvo akapihwa nzvimbo yekugara muHyrcania uye akaroora Rhodogune, mwanasikana waMithridates. Muna 129 BC, madzinza eSaka akapinda uye akapamba Hyrcania, pamwe nemamwe matunhu ekumabvazuva, uye vakakunda nekuuraya madzimambo maviri akateedzana eArsacid. Nokukurumidza pashure pokukwira kwake pachigaro choumambo muna 124 BC, Mithridates II, akadzorera Hyrcania ndokutangazve kutonga kweArsacid. 