 Nyorai kuenderera mberi kweiyi ndima - Antiochus III akatanga mushandirapamwe mukuru wekutora Parthia neBactria muna 210 kana 209 BC. Pasinei zvapo nokukunda kwakati, haana kubudirira, asi akakurukura rugare naArsaces II. Uyu wokupedzisira akapiwa zita roumambo chiGiriki: basileus mukutsinhana nokuzviisa kwake pasi paAntiochus III somukuru wake. VaSeleucid vakanga vasisakwanisi kupindira munyaya dzevaParthia zvichitevera kuwedzerwa kwekupinda neRepublic yeRoma uye kukundwa kwevaSeleucid paMagnesiamuna 190 B.C. Priapatius r. c. 191176 BC akatsiva Arsaces II, uye Phraates I r. c. 176171 BC pakupedzisira akakwira pachigaro cheumambo cheParthia. Phraates I akatonga Parthia pasina kumwezve kupindira kwevaSeleucid. 