 Nyorai kupfuurira kweiyi ndima - Zvakare, mufambiro wake wakakunda kurumbidzwa kwaCalvin 10 May 1563, uye iye mumwe wevanhu vanodzokororwa kazhinji mukunyora kwake kwenguva iyoyo; anoratidza kakawanda kuzivikanwa kwekupindira kwake nokuda kwechinangwa cheEvhangeri; uye chimwe chezvakanyorwa zvake zvekupedzisira mumutauro wechiFrench, chakatumirwa kubva pamubhedha worufu rwake 4 April 1564, chakanangidzirwa kwaari. Nepo Renée akaramba asingavhiringidzwi muhondo yechipiri yorudzidziso 1567, muhondo yechitatu 1568-70 nhare yake yakanga isingacharemekedzwi senzvimbo yokupotera vatendi biyake. Pane rumwe rutivi, iye akabudirira mukununura chiverengero chakati chavo kubva mukuurawa kukuru kwousiku hwaSaint Bartholomew, apo iye akaitika kuva muParis. Vakamusiya asina kuvhiringidzwa panguva iyoyo, kunyange zvazvo Catherine de Medici achiri kutsvaka kumuita kuti adzokere, chikumbiro chaasina kuteerera. 