 Simons akatanga basa rake rokunyora nhau muna 1964 somunyori wenhau weAssociated Press. Nyanzvi munyaya dzeAsia, akataura zvakawanda nezvehondo, kusagadzikana kwevanhu, zvematongerwo enyika, uye zvehupfumi, achishanyira Pakistan, Afghanistan, Japan, South Korea, Malaysia, Singapore, Vietnam, Philippines. Muna 1971, akabatana neWashington Post uye akashanda semunyori muIndia neThailand mumakore mashomanana akatevera. Kubva muna 1982, Simone akashanda semunyori wenhau weMercury News muTokyo. Chimwe chezvirongwa zvake mukati menguva iyi chaiva nyaya dzakatevedzana nemanyori Pete Carey naCatherine Ellison pamusoro pekuchinjwa kukuru kwehupfumi kunze kwenyika neMutungamiri wePhilippines Ferdinand Marcos nevamwe vake. Ari pabasa muTokyo muna 1985, Simons akanga achitsvakurudza mamiriro ezvinhu erufu rwemunhu wezvematongerwe enyika Benigno Aquino, paakawana mashoko pamusoro pezviitiko zvemari zvaMarcos. Muna 1986, vatori venhau vatatu vakapiwa mubayiro wePulitzer Prize for International Reporting. Gore rimwe gare gare, Lewis Simons akabudisa bhuku pamusoro pechinjo yePhilippineZvakakodzera Kufira. 