 Nyora kupfuurira kweiyi ndima - Zvisinei, mukudzoka kusingatarisirwi, Cissé akakwanisa kupinda semutambo wemaminitsi makumi manomwe nemashanu mumutambo wechipiri weLiverpools Champions League quarter-final tie neJuventus musi wa13 Kubvumbi 2005. Akaenderera mberi achihwina zvibodzwa zviviri zveLiverpool mumutambo wavo wekupedzisira wePremier League wemwaka, kukunda 21 pamusoro peAston Villa uye zvakare akashandura chirango mukukunda kweLiverpool kurova kwechirango pamusoro peAC Milan mumutambo weChampions League. Munguva yemwaka wa2005-06, maneja weLiverpool Rafael Benítez akaendesa Cissé kurudyi parutivi pazviitiko zvakawanda. Kunyange zvazvo kufamba kwake kwakamuita kuti akwanise kuita basa rakadaro, zvaiva nemubvunzo kana aizofara kuramba achiita basa iri pane kuti arambe ari panzvimbo yaanoda semurwi. Akarova zvibodzwa zviviri apo Liverpool yakakunda 2005 UEFA Super Cup. Cissé akarovawo chibodzwa chekutanga cheLiverpool mu2006 FA Cup Finalnebhora rinotsvedza kupfuura muchengeti weWest Ham United Shaka Hislop. Liverpool yakaenderera mberi ichikunda 31 pakurohwa. Akapedza mwaka wa2005-06 aine zvibodzwa 19 mumakwikwi ese. 