 Guardado, mutambi wenhabvu wenyika yeMexico kubvira muna 2005, akamiririra nyika iyi mumakwikwi mana eWorld Cup, makwikwi mana eGold Cup akahwina mukombe weWorld Cup muna 2011, 2015 uye 2019 makwikwi maviri Copa Américas uye maviri Confederations Cups, kuhwina pamusoro pe160 caps. 