 Type 2 diabetes mellitus T2DM is associated with increased fracture risk despite normal to increased bone mass, thus suggesting poor bone quality. This study is aimed at weighing the effect of an exercise intervention program on parameters of bone quality in patients with type 2 diabetes mellitus. Two hundred patients with T2DM will be randomized to supervised exercise training on top of standard care exercise, EXE, group; n100 versus standard care control, CON, group; n100 for 24 months. 