 Eighty percent of PWD have behavioral or psychological disturbances, including 40 that are aggressive behaviors. The prevalence of pain in PWD is about 60, and it is a strong predictor of aggression. The biopsychosocial model of pain posits that pain is bidirectionally related to psychological factors ie, depression and social support factors ie, quality of caregiverPWD relationship in addition to biological factors. Thus, depression and quality of the caregiverPWD relationship can be seen as pain-related features. Caregivers are ideally suited to help address pain, depression, and the caregiverPWD relationship, thus preventing the development of aggression; but they need tools to assist them in identifying and managing these symptoms. 