 Age at diagnosis, anthropometry height and weight, Tanner stage - breast, Tanner stage - pubic hair, GnRH test LH and FSH response, thyroid parameters, estrogen, prolactin, 17OHP, androstenedione, dihydroepiandrosteron DHEA, testosterone, inhibin B, SHBG, AFP, kisspeptin, human chorionic gonadotropin HCG, bone age, MRI of the cerebrum, US of internal genitalia, and exposures to environmental chemicals known to affect secondary sex characteristics. 