 - Subjects with any values for alanine aminotransferase ALT, aspartate aminotransferase AST, or creatinine that are above the upper limit of normal ULN; any values for platelets or haemoglobin that are below the lower limit of normal LLN; or any out of normal range values for white blood cells WBC, reticulocytes, serum sodium, or serum potassium. 