 4. Subject has a known allergy to contrast medium that cannot be adequately pre-medicated, or any known allergy to thienopyridine, aspirin, both heparin and bivalirudin, L-605 cobalt-chromium Co-Cr alloy or one of its major elements cobalt, chromium, tungsten and nickel, acrylic, fluoropolymers, silicon carbide, PLLA, sirolimus or everolimus. 