 As stated by Pandey et al Pandey 2005, a successful implantation during pregnancy requires a balanced equilibrium between coagulation, fibrinolysis and vascular remodeling by the process of angiogenesis in order to avoid excess fibrin accumulation in placental vessels and intervillous spaces Buchholz 2003. However, thrombosis in decidual vessels is reported to be one of the major causes of RPL Arias 1998 and could be explained by excessive thrombosis of the placental vessels, placental infarction, and secondary uteroplacental insufficiency. 