 a. Record study drug timing of infusion before the PK samples are obtained - this includes startstop times of infusion and amount given b. Assess and record AEs from the time of the first dose of study drug. c. Assess and record SAEs from the time of the first dose of study drug. d. Record all concomitant antimicrobials and vasopressors administered e. Collect blood for PK analysis Appendix 2 f. Record result for clinical laboratory assessments obtained per local standard of care one time daily while on study drug. 