 A comparator vaccine is included at 2:1 ratio StreptAnovaTM to comparator. Assignment to StreptAnovaTM or comparator vaccine will be both randomized and observer-blinded. Three 3 0.6 mL doses 600 μg protein of StreptAnovaTM or 0.5 mL doses of comparator will be administered on days 0, 30 and 180 N 30 StreptAnovaTM, 15 comparator; each subject will receive three doses of the same treatment. 