 Diabetic peripheral neuropathy DPN represents a diffuse symmetric and length-dependent injury to peripheral nerves that has major implications on quality of life QOL, morbidity, and costs from a public health perspective. Painful diabetic neuropathy affects approximately 16 of patients with diabetes. Pharmacological agents used in the management of painful DPN mainly include tricyclic antidepressants, selective serotonin and norepinephrine reuptake inhibitors, opioid, and anti epileptic drugs. The available treatment options do not give total relief, are not effective in all patients, and only about one-third of patients may achieve more than 50 pain relief. Hence newer therapies are required for the treatment of DPN. The primary outcome measures will be the change from baseline to end of treatment in the mean 24-hour average pain intensity. 