 An observational multicenter prospective inception cohort will be conducted within the PRESAGE-Network, an ongoing active network on drug safety in older adults in France involving a sample of general practitioners GPs and pharmacists, for an active surveillance of drug safety in older adults. GPs and pharmacists will prospectively include all octo patients they care for, newly treated with an oral anticoagulant VKA or DOA for nv AF and will follow them during 2 years at least. 