 The trial will be 12 weeks randomized, cross-over and double blinded with 2 treatment intervention sucralose and aspartame , there will be a run in period 4 weeks, then phase 1 treatment period for two weeks followed by four weeks washout period then phase 2 treatment period2 weeks. Healthy, normglycemic 5.6 mmolL males and females 17 total of age 18-45 y with a body mass index BMI 20-25 kgm2 will be recruited. 