 - at least one not sufficient controlled risk factor : Diabetes mellitus HbA1c7,5, smoking, lack of physical activity less than 60 minutes of light physical exercise per week, heightened stress level PSS-4 5, arterial hypertension blood pressure despite medication repeatedly heightened 14090 or in a 24-hour measurement 13585 mmHg, hypercholesteremia LDL 130 mgdl 