 Sequential cohorts of 10 subjects will be randomized 8:2 to receive multiple doses of ACH-0137171 or placebo for 4 days Days 1 through 4 with a single dose on Day 5 followed by a complete pharmacokinetic profile. Dosing will be 300 - 600 mg administered either every 12 hours or every 6 hours maximum daily dose of 2400 mg. All doses will be administered with food. 