 For all children receiving the booster dose of vaccine and their GP, practice nurse and child health department will be informed. If the child is also due for their other preschool booster vaccines the 4 in 1 Diphtheria, tetanus, tetanus and polio vaccine, the combined HibMenC vaccine and the combined measles, mumps, rubella vaccine MMR these will also be offered, but will not form part of the study assessment. 