 7. Absolute neutrophil count ANC 1000μl, platelets 75,000μl, hemoglobin 8.5 gmdL; serum creatinine 1.4 mgdL; bilirubin 1.8 mgdL; ALT or AST 2.5 x ULN if no demonstrable liver metastases or 5 x ULN in presence of liver metastases; alkaline phosphatase 3 x upper limit of normal; calcium 11.0 mgdL. 