 This is a single-arm, open-labeled and phase II futility study. Application of Remote ischemic conditioning RIC as an adjunctive therapy to medication were involved in the study. RIC consisted of five cycles of 5-min inflation 200 mmHg and 5-min deflation of cuff on bilateral upper limbs twice a day. The study is to test whether RIC is effective in preventing ischemic evens after a minor ischemic stroketransient ischemic attack within 3 months and to explore the safety and compliance of chronic RIC. Medication strategy is based on physicians best judgement. 