 Since standard endoscopy with pinch biopsies of the overlying mucosa often fails to provide an adequate sample for analysis, multiple other modalities to sample the lesion have been utilized: EUS-guided fine needle aspiration EUS-FNA, EUS-guided core needle biopsy EUS-CNB, bite-on-bite forceps biopsies, EUS-guided single-incision with needle knife SINK and endoscopic resection. 