 - Patients with reproductive potential must use an acceptable contraceptive method, such methods include: 1 Male hormonal contraception; 2 Partner without reproductive potential, including post-menopausal status or history of tubal ligation; 3 Partner with intrauterine device IUD or contraceptive vaginal ring; 4 Partner takes oral contraceptive pill, wears contraceptive patch, or has contraceptive implant; 5 Routine use of barrier method, such as condoms or diaphragm, during sexual intercourse 