 11. Current use of a prohibited medication. The following medications or non-drug therapies are prohibited: a Other anti-cancer therapy while on study treatment, b Because the composition, PK, and metabolism of many herbal supplements are unknown, the concurrent use of all herbal supplements is prohibited during the study including, but not limited to, St. Johns wort, kava, ephedra ma huang, gingko biloba, dehydroepiandrosterone DHEA, yohimbe, saw palmetto, or ginseng 