 - Screening supine 12-lead ECG demonstrating QTcF time from ECG Q wave to the end of the T wave corresponding to electrical systole QT corrected for the heart rate using the Fredericias formula 450 msec or a QRS interval time from ECG Q wave to the end of the S wave corresponding to ventricle depolarization 120 msec. If QTcF exceeds 450 msec, or QRS exceeds 120 msec, the ECG should be repeated two more times and the average of the three QTcF or QRS values should be used to determine the subjects eligibility. 