 HIV has a negative intergenerational impact on families, particularly children with HIV parents. In order to improve the social, behavioral and mental health outcomes for families affected by HIV, we have designed the Family-to-Family F2F intervention that includes the critical, universal, program components identified by the NIMH Intervention Workgroup. All efficacious intervention programs: frame the problem by providing information and shaping beliefs; enhance skills; establish supportive relationships; and remove environmental barriers to behavior change e.g., HIV testing, ARV. We aim to evaluate a generic intervention approach including these components that is culturally-tailored to families affected by HIV in a specific country, Thailand. 