 - To compare the two intervention arms with respect to overall survival OS; patient-reported outcomes using the SF-36, FACIT-F, PSQI, and HADS questionnaires; objective markers of physical fitness using body mass index, hip and waist circumference, submaximal exercise testing, and the Seniors Fitness Test; physical activity behavior using the Total Physical Activity Questionnaire TPAQ; safety profile as assessed by NCI CTCAE version 3.0; serum levels of insulin i.e., IGF-1, IGF-2, and IGFBP3; cytokine levels i.e., IL-1β, IL-6, IL-2, IL-4, IL-8, IL-10, IL-12, TNF-α, IFN-γ, and GM-CSF and C-reactive protein levels; economic evaluations including cost-effective and cost-utility analyses; and predictors of physical activity adherence using the Social-Cognitive Determinants of Exercise Measure questionnaire. 