 In this study, subjects will be assigned to one of two treatment groups. Patients in the first group will have their hipbuttock or forearm treated with the microdermabrasion machine. There may be only one treatment or as many as 6 on the same area, spaced up to two weeks apart. The treated area will be on either the right or left buttock andor forearm andor underarm. An area of approximately 10x10 cm 4x4 inches will be treated. Skin biopsies will be performed on up to nine different times, up to six months following dermabrasion, on treated andor untreated skin from the buttocks, forearm andor underarm. Therefore, a total of up to nine biopsies will be taken from subjects in this group. The biopsies will be 4 mm or smaller in size, or about the size of a pencil eraser. Subjects can expect to make six visits to the hospital over a 3-4 week period of time. 