 1. Medications or agents that might alterimpair glucose metabolism insulin, glucocorticoids, corticosteroids, megace during the 3 months prior to enrollment or at any time during enrollment. Volunteers who developed type 2 diabetes after HIV-infection or after starting anti-HIV medications, who are receiving insulin sensitizers metformin, meglitinides, alpha-glucosidase inhibitors or insulin secretagogues sulfonylureas, but still do not have their blood sugars in control defined as IGT above are eligible. 