 Previous research revealed that the maximum ChoNAA index CNImax threshold of 2.0 predicted tumor infiltration with probabilities of 90 in HGGs and 87 in LGGs. However, when tumors are located near convex or ventricular systems, scalp fat and skull lipids could affect the quality of the MRS imaging. Moreover, the elevation of CNImax can be detected in other intracranial tumors such as lymphoma and some non-neoplastic lesions such as those caused by demyelination, encephalitis and vasculitis. 