 No malaria control trial with either Olyset Plus or Actellic CS is currently being proposed elsewhere. Olyset Plus seems ideally suited - judging by the CDC bioassay test with permethrin and the synergist PBO and WHO cone bioassay tests with Olyset Plus - to provide protection against the local pyrethroid resistant An gambiae. IRS with Actellic CS seems ideally suited to provide long term transmission control. A trial of both interventions is essential to restore confidence in vector control. By itself Olyset Plus may be sufficient to provide personal protection if used every night but it may not be sufficient to provide transmission control in the entire community. An effective IRS is probably the more efficient way to reduce transmission quickly but IRS campaigns cannot be sustained year after year because of the expense, nor is this desirable because of the risk of resistance. The combination of LLIN and IRS may be required to drive transmission down to low levels whereafter the Olyset Plus should be sufficient to keep prevalence and transmission low. 