 3. Female subjects of childbearing potential must agree to use one of the following forms of contraception from screening through the last study visit: hormonal oral, implant, or injection begun 30 days prior to screening; barrier condom, diaphragm, or cervical cap with spermicide; intrauterine device IUD. Acceptable contraceptive options may also include abstinence, relationship with a same sex partner or partner who has had a vasectomy at least six 6 months prior to the screening visit 