 - A male participant: a Must be sexually abstinent defined as refraining from sexual intercourse from Day 1 day of dosing until 90 days after study drug administration, OR b Who is sexually active either heterosexual, including with a pregnant woman, or homosexual must agree to use a barrier method of contraception eg, condom from Day 1 day of dosing until 90 days after study drug administration, AND c Who is sexually active with a woman of childbearing potential must agree to use a barrier method of contraception eg, condom from Day 1 day of dosing until 90 days after study drug administration, in conjunction with this female partner using a highly effective contraceptive such as implantable progestogen-only hormone contraception associated with inhibition of ovulation; intrauterine device; intrauterine hormone-releasing system, combined estrogen- and progestogen- containing hormonal contraception associated with inhibition of ovulation: oral, intravaginal, or transdermal; progestogen-only hormone contraception associated with inhibition of ovulation: oral or injectable d Must agree not to donate sperm from Day 1 day of dosing until 90 days after study drug administration 