 A further study extension changed the 3-pill EFVFTCTDF regimen to a 2-pill regimen of EFV Truvada TVD: a fixed-dose combination pill containing FTCTDF, once daily without regard to meals, and continued to evaluate the efficacy and safety of the two regimens for a further 48 weeks up to a total study treatment duration of 144 weeks. The regimen of CBVEFV continued to be dosed as 2 pills CBV, twice daily in the morning without regard to meals EFV once daily, without regard to meals. 