 Beginning in month 4, patients are introduced to the Patient Navigator who provides them with telephone and e-mail contact on an Appointment Reminder Card, and develops a plan for eliminating identified barriers andor addressing immediate concerns. Patients plans may include contacting others on behalf of the patient, coaching the patient on how to solve a problem, referring to resources within City of Hope COH or in the community, and investigating possible solutions. Patients are also oriented to COHs services, open clinical trials, and resources. Navigation of care includes assistance during initial and ongoing evaluations by all cancer specialists, during initiation and completion of all primary treatment, and through the first post-treatment follow up. Patients are contacted weekly for 8 weeks of the study and at least once a month for 9 months. 