 Oxidative stress and antioxidant status : the investigators will measure 8-oxo-7, 8-dihydro-2-deoxyguanosine 8-oxodG, a major product of ROS-induced oxidative stress, in urineplasma of children using commercial ELISA kits. Reduced glutathione GSH is considered as an important scavenger of reactive oxygen species ROS, and its ratio with oxidized glutathione GSSG is used as a marker of oxidative stress. The antioxidant status GSHGSSG in whole blood will be assessed by measuring GSH and GSSG using commercial kits. 