 Study LIPO-202-CL-31 is a multi center, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of two different doses of LIPO-202 versus placebo on submental bulging due to subcutaneous fat. Approximately 150 participants of either gender who have a Moderate Bulge or Large Bulge in the submental fat on Patient-Reported Submental Bulging Scale PR-SBS and Clinician-Reported Submental Bulging Scale CR-SBS will be recruited for this study. 