 - Participants with a high risk factor for nephrogenic systemic fibrosis NFS, including renal failure on dialysis, heart disease, diabetes, single kidney, hypertensionhypotension, multiple myeloma, peripheral vascular disease, or taking of specific medications loop diuretics, NSAIDs, aminoglycosides, vancomycin, amphotericin B, chemotherapy, or immunosuppressants. 