 Blood tests will be obtained as per routine standard of care weekly during the initial six weeks of combined radiation and chemotherapy and on days 21 and 28 - 2 days of each cycle of monthly temozolomide.After the initial MRI or CAT scan, subsequent MRIs or CAT scans will be obtained per standard of care: four weeks after completion of radiation and then generally after every two cycles of chemotherapy unless medically indicated at other time points. 