 Gastroesophageal reflux disease GERD remains a major problem in the United States affecting about 20 of Americans. Upper endoscopy EGD is commonly used to diagnose and grade GERD based on mucosal breaks and erosions. It is now evident from multiple studies however that the majority of GERD patients 50-70 have negative EGDs.These patients are refered to as Non Erosive Reflux Disease NERD patients.Confocal Laser Microscopy CLM is a new endoscopic technique that offers the advantage of detecting histologic changes during real time endoscopy and thus can diagnose NERD. We thus propose to study the sensitivity and specificity of CLM in predicting NERD. We hypothesize that CLM can reliably diagnose NERD in the appropriate clinical setting based on intrapapillary capillary loop patterns. This will be a pilot study after which a randomized trial will evaluate the reversibility of these changes after PPI therapy as seen by CLM 