 This study is the umbrella or screening study in a group of 5 studies known as the BATTLE Biomarker-integrated Approaches of Targeted Therapy of Lung Cancer Elimination program. In order to participate in one of the research studies, you must first agree to take part in this screening study, which will be used to determine if you are eligible. After participating in this study, you may be assigned to a study that is using an investigational drug. The investigational drugs to be used in each of the 4 studies are not approved by the Food and Drug Administration FDA for commercial use in this setting; however, the FDA has permitted its use in these research studies. 