 Cerebral gliomas account for 29 of all primary brain tumors and 81 of malignant brain tumors. Structural imaging with MRI is the most commonly accepted method for obtaining radiological information leading to the diagnosis. However, most low-grade gliomas LGGs, and even some high-grade gliomas HGGs, are not enhanced in MRI-contrast imaging. Despite applying supplementary MRI sequences such as T2 FLAIR and DWI, non-enhancing gliomas remain difficult to differentiate from nontumorous lesions, including those arising from demyelination, inflammation, encephalomalacia and gliosis. 