 6. Patients must have diarrhea symptoms, judged secondary to the systemic therapy, combined systemic therapy, andor radiation, and must be requiring loperamide or similar Imodium for symptom management. For the purposes of this study, diarrhea will be defined as three or more loose or liquid stools per day or loose watery stool greater volume of stool that occur more frequently than usual and lasting for more than three days. 