 - EVALUAITON: During the initial phase, 14 patients will be accrued for this study. If the number of patients response to calcitriol and 5-fluorouracilmitomycin Cleucovorin is less than 114, the study will be stopped. However there is one patient who responses to calcitriol and 5-fluorouracilmitomycin Cleucovorin, the new 14 patients will be accrued during the secondary phase of study. 