 - Acquired cardiovascular disease from invasive or non-invasive examinations such as coronary angiography, nuclear medicine, stress echocardiography, carotid plaque ultrasound, previous myocardial infarction, ACS, coronary revascularization PCI, CABG, and other arterial revascularization, ischemic cerebrovascular accident, peripheral arterial disease PAD Diabetes mellitus type 1 or type 2 with one or more cardiovascular risk factors orand target organ damage such as microalbuminuria: 30-300 mg Patients already diagnosed with hypercholesterolemia and non-regulated who are going to receive Rosuvastatin according to established clinical practice 