 All patients who have enrolled will receive the usual care for the postoperative period. The study drug will be in addition to usual flap monitoring, patient vital sign monitoring, progression of mobilization, drain management, along with the other care provided for these patients. Patients also will have the same background analgesic and anti-emetics medications ordered postoperatively, which is included on a standardized pre-printed order form at the Halifax Infirmary for this particular surgery. 