 Pompe disease also known as glycogen storage disease type II is caused by a deficiency of a critical enzyme in the body called acid alpha-glucosidase GAA. Normally, GAA is used by the bodys cells to break down glycogen a stored form of sugar within specialized structures called lysosomes. In patients with Pompe disease, an excessive amount of glycogen accumulates and is stored in various tissues, especially heart and skeletal muscle, which prevents their normal function. The primary objective of this study is to identify potential candidates for future clinical studies in Pompe disease. 