 - subject has received chronic i.e., greater than 15 consecutive days of immunosuppressive therapy e.g. azathioprine, 6 mercaptopurine or corticosteroids within 30 days of screening. Intermittent use of oral or rectal immunosuppressive therapy or corticosteroids within 30 days of screening is permitted. Intravenous use of corticosteroids within 30 days of screening is not permitted. 