 2. Patients applying to one of the followings 2.1. BMI 30kgm2 or over 2.2. BMI 27-29.9kgm2 with hypertension in a proper treatment and blood pressure controlled SBP 145mmHg, DBP 95mmHg 2.3. BMI 27-29.9kgm2 with non-insulin-dependent diabetes mellitus and fasting blood glucose 7.8mmolL140mgdL 2.4. BMI 27-29.9kgm2 with hyperlipidemia in a proper treatment 2.5. BMI 27-39.9kgm2 and Total cholesterol 236mgdL or over or Triglyceride 150mgdL or over at screening 