 9. Impaired cardiac function or clinically significant cardiac diseases, including any of the following: a History of acute coronary syndromes including myocardial infarction, unstable angina, coronary artery bypass grafting, coronary angioplasty, or stenting or symptomatic pericarditis less than 12 months prior to screening b History of documented congestive heart failure New York Heart Association functional classification III-IV c Documented cardiomyopathy d Patient has a Left Ventricular Ejection Fraction LVEF less than 50 as determined by Multiple Gated acquisition MUGA scan or echocardiogram ECHO at screening e History of ventricular, supraventricular, nodal arrhythmias, or any other cardiac arrhythmias, long QT Syndrome or conduction abnormality within 12 months prior to starting study drug 