 Clinic hypertension CH and morning hypertension MH were defined as systolic BP SBP 130 mmHg andor diastolic BP DBP 85 mmHg; clinic normotension CN and morning normotension MN were defined as SBP 130 mmHg and DBP 85 mmHg, respectively. The reason underlying that same threshold was used for both clinic and morning values was based on criteria of the 1999 WHO-International Society of Hypertension guidelines, because this study started in 1999. Based on HBP, subjects were divided into MH and MN patients, and anti-hypertensive drug use was determined in each group. In addition, based on CBP, subjects were divided into CH and CN patients. These patients were followed using the same methods used for MH and MN patients. 