 - Has good general health as determined by medical history, general clinical examination, vital signs systolic blood pressure 140 mm Hg, diastolic blood pressure 90 mm Hg, heart rate 100 beats per minute, and body temperature of 36.1-37.8 C, and clinical laboratory test results; and has a World Health Organization WHO performance status of 0 or 1 see Appendix A for WHO performance status scale 