 - Part 2: Histologically or cytologically confirmed, locally advanced or metastatic: NSCLC squamous or non-squamous cell carcinoma; up to 2 prior treatment regimens, Colorectal Cancer up to 2 prior treatment regimens, Pancreatic Cancer up to 1 prior treatment regimen, Ovarian cancer up to 2 prior treatment regimens, or Sarcoma up to 2 prior treatment regimens, according to cohort availability 