 a. Pregnant patients b. Pediatric patients unable to donate at least 51 mL of blood per NIH guidelines no more than 5 mLkg in a single day and no more than 9.5 mLkg over any 8 week period c. Patients with current substance abuse or alcoholism self-report d. Patients diagnosed with more than one autoimmune andor inflammatory disease, exception - asthma is permissible e. Corticosteroid therapy equivalent to 10 mgday of prednisone within the last 4 weeks f. Immunomodulatory therapies within the last 12 months such as Interferon, Glatiramer Acetate, Natalizumab, Fingolimod g. Immunosuppressive medication at any time prior to enrollment such as Cyclophosphamide, Mitoxantrone, Imuran, Cellcept, Methotrexate, Rituximab, Alemtuzumab h. Any prior or current Anti-tumor necrosis factor anti-TNF treatments i. Any prior or current use of experimental drugs tested in Phase I, II, or III clinical trials 