 Severe Traumatic Brain Injury TBI can result in a long-lasting altered state of consciousness. At present, the underlying neurological determinants of recovery in patients with disorders of consciousness DOC after a severe TBI are not well understood, and individual prognosis is very limited. Moreover, the rate of misdiagnosis between different states of altered consciousness by standard clinical scales is high, which further impacts on the clinical prognosis. In this project, multimodal neuroimaging measures will be applied and whole-brain data will be obtained from patients recovering from severe TBI in a longitudinal fashion. Patients will be examined at four time points during the sub-acute stage: immediately after admission to the neurorehabilitation unit, after ten weeks of admission, at discharge, and after one year of the TBI episode. Brain connectivity will be assessed with functional Magnetic Resonance Imaging fMRI combined with electroencephalography EEG, structural MRI, diffusion MRI, high-density EEG hdEEG alone, and hdEEG combined with Transcranial Magnetic Stimulation EEG-TMS, and 18F-fluorodeoxyglucose positron emission tomography FDG-PET. 