 The researchers propose a Phase II randomized, double-blind, placebo-controlled trial of 180 healthy postmenopausal women experiencing at least 5 hot flashes per day or 35 hot flashes per week. Women will be randomized to one of three arms: 4.5 gramsday dry weight of extract of MF101, 9.0 gramsday dry weight of extract of MF101 or placebo for 12 weeks. 