 10. Adequate organ function as demonstrated by the following: Direct bilirubin equal to or less than 1.5 x upper limit of normal ULN, Serum creatinine equal to or less than 1.5 x ULN, AST SGOT and ALT SGPT equal to or less than 2.5 x ULN unless considered to be related to MF or patient has known history of Gilberts, in which case it must be equal to or less than 5 x ULN 