 - Presence of current or suspected serious chronic diseases such as cardiac or autoimmune disease HIV or other immunodeficiencies, insulin-dependent Type 1 and Type 2 and NIDDM diabetes excluding glucose intolerance if Exclusion criteria 3 is met, progressive neurological disease, severe malnutrition, acute or progressive hepatic disease, acute or progressive renal disease, psoriasis, rheumatoid arthritis, uncontrolled asthma, epilepsy or obsessive compulsive disorder, skin carcinoma excluding non-spreadable skin cancers such as basal cell and squamous cell carcinoma. 