 This is an implementation research study designed to evaluate a defined strategy, NIATx, for its effectiveness in installing and sustaining evidence-based integrated services for persons with co-occurring substance use and mental health disorders. This study is a cluster randomized wait-list control group design, in which a cohort of 25 addiction treatment agencies receives the active NIATx approach during an index 12 month period. The second wait-list cohort of 25 addiction treatment agencies activates NIATx strategies during a second index 12 month period. The primary subjects of the research are the treatment agencies themselves. The study specific aims are: 