 - Patients must have adequate pulmonary function studies 50 of predicted on mechanical aspects Forced Expiratory Volume 1 FEV1, Forced Vital Capacity FVC and diffusion capacity DLCO 50 of predicted. If the patient is unable to complete pulmonary function tests due to MM related pain or other conditions, an exception may be granted if the principal investigator documents that the patient is a candidate for high dose therapy. 