 The preferred source of stem cells will be peripheral blood stem cells PBSC induced and mobilized by treatment of the donor with G-CSF for 5-6 days. PBSC obtained through 2-3 leukaphereses will be Isolex 300i separated CD34 stem cell column selected and E-rosette depleted E-. The CD34 E peripheral blood progenitors will then be administered to the research participants after they have completed cytoreduction. If the use of CD34 E- PBSC is not possible, the alternative graft will consist of bone marrow derived stem cells T-cell depleted by soybean agglutinin and E-rosetting SBA-E-. 