 1. Among school-aged children with mild to moderate asthma, those children with increased airflow limitation i.e. low FEV1FVC at the end of CAMPCS NormalLow and LowLow groups have elevated markers of inflammation related to proteolysis i.e. neutrophil elastase, matrix metalloproteinase-9 MMP9, and tissue inhibitor of metalloproteinase-1 TIMP1 and neutrophils in sputum. 