 WBC count: or 2.5 x institutional ULN; Absolute granulocyte count: or 1,500mm3 Platelets: or 100,000mm3 Total bilirubin: or 1.5 x institutional ULN Serum creatinine: or 1.5x institutional ULN AST and ALT: or 2.5 x institutional ULN Serum albumin: or 3.0 gdL 