 - Histologically confirmed metastatic cancer of the prostate stage D2 or Tx Nx M1 M1a with measurable bone or visceral lung, liver, etc. metastases radiographic conformation was necessary in the event of a questionable bone scan detection in conjunction with only slightly elevated PSA levels at least 20 ngmL or less than or equal to 50 ngmL. The prostatic carcinoma could have been diagnosed at an earlier stage and treated without castration. 