 We will test the efficacy of IPT using a variety of outcome measures at different time points of the treatment. Those scales will evaluate the patients depressive symptoms, psychosocial functioning and quality of life. Patients that are deemed eligible for the study will have IPT for twelve weeks. Patients will receive twelve 50-minute sessions over 16 weeks. To facilitate access to treatment, sessions 1,2,3,4, 8 and 12 will be in person, while all others will in be person or over the telephone according to the patients choice. Sessions will be audiotaped and periodically reviewed by experienced supervisors to assess therapists adherence to IPT technique. This taping will be optional and is covered in a separate consent form. This pilot study is to prove feasibility and acceptability of IPT in this population and to show preliminary efficacy. 