 CIDEIM, Centro Internacional de Entrenamiento e Investigaciones Medicas, is conducting a research study about the disease Cutaneous Leishmaniasis, which is caused by the Leishmania parasite and causes skin sores. Researchers hope to find out how the human body defends against Leishmania. A total of 472 individuals, ages 7 to 70 years, belonging to one of the following groups will be included in this study: recurring disease, chronic disease, disease with no sign or symptoms asymptomatic, and healthy individuals. Study procedures will include a questionnaire and buccal swab swabbing of the inside of the cheek with a cotton or wooden applicator. In addition, asymptomatic and healthy individuals will provide a blood sample. Study participation will be up to 1.5 hours. 