 - Costs: see elsewhere. To measure the separate effect of the two diagnostic strategies and their related treatment regimes primary outcome the proportion of respondents who are still disease-free after hepatic resection CT diagnosis 9 month after treatment will be estimated by applying life-table analysis Kaplan-Meier. These estimated proportions will be used in the cost-effectiveness analysis see section: Economic evaluation. A similar analysis, however, extended with quality of health outcomes utilities: measured by the EQ-5D will be performed for the 3 distinct clinical states that can be distinguished: 1 no laparotomy, no cure, 2 laparotomy hepatic resection, possible cure, 3 laparotomy no hepatic resection, no cure. In order to perform this so-called Q-TWIST analysis the EQ-5D will be measured at baseline and each month during follow-up. The results of this aggregated analysis will be expressed as the number of quality-adjusted months survival for the two treatment strategies. Another contribution of this approach is that all the information can be depicted in one single figure for each of the two strategies, clearly dividing the impact of the three distinct states and their occurrence in time.Quality-adjusted life years QALYs will be computed in order to perform a conventional cost-utility analysis for the two diagnostic strategies. Utilities EQ-5D will be based on the mean values for the two groups of patients at the 10 occasions baseline, month 1-9. Contrary to the above-mentioned Q-TWIST analysis, no distinct states will be recognized, whereas cost will be incorporated. 