 7. Contraindication to epinephrine, such as concurrent administration of ergot-type drugs, monoamine oxidase MAO inhibitors or antidepressants of tryptoline or imipramine types, conditions where the production or exacerbation of tachycardia could provide fatal e.g., poorly controlled thyrotoxicosis or severe heart disease or any other pathological conditions that might be aggravated by the effect of epinephrine. 