 II. To evaluate CEUS as a potential early response assessment biomarker by comparing the CEUS rating result to computed tomography CTmagnetic resonance imaging MRI rating results. Exploratory III. To examine the agreement between CEUS versus CTMRI determined treatment response within each radiologist rater. Exploratory IV. To examine the agreement between CEUS versus CTMRI determined treatment response based on the consensus rating result from the two radiologist raters. Exploratory V. To explore potential quantitative biomarker from all possible parameters that can be extracted from CEUS data for assessing an early treatment response to neoadjuvant therapy NAT in sarcoma using receiver operating characteristic ROC curve when predicting radiologists rated binary outcome: responders versus non-responders. Exploratory VI. To collect preliminary data for shear wave elastography SWE in the same patient population. Exploratory 