 - Patients must have normal organ and marrow function as defined below, within one week prior to randomization: absolute neutrophil count1,500mL platelets100,000mL total bilirubin: within normal institutional limits ASTALT2.5X institutional upper limit of normal creatinine1.5X institutional upper limit of normal urine dipstick for proteinuria of less than 1. If urine dipstick is 1 then a 24 hour urine for protein must demonstrate 500mg of protein in 24 hours to allow participation in the study. 