 - In Group A: For each cohort, 10 elderly non-Asian adults greater than or equal to 65 years old, with at least 2 participants 70 years and 75 years old, at least 2 participants 75 years old, with 5 participants of each sex; In Group B: For each cohort, 10 young healthy non-Asian adults 18 to 45 years old, inclusive, matched to elderly participants in the same cohort by gender and body weight plus or minus -5 kilogram kg; In Group C: For each cohort, 10 healthy Japanese adults 20 to 60 years old, inclusive, who have resided outside of Japan for less than or equal to 10 years, have parents and maternal and paternal grandparents who are Japanese, who primarily consume a Japanese diet, with 5 participants of each sex 