 Fat mass and fat-free body mass will be evaluated by dual energy x-ray absorptiometry DXA, and intra-abdominal fat volume and thigh muscle area will be measured by computed tomography CT. Bone mineral density BMD of the total body, lumbar spine, and proximal femur will be measured by DXA and biochemical markers of bone resorption and formation. Glucose tolerance and insulin response will be evaluated using an oral glucose tolerance test. 