 - Hematology values within the following limits: a Absolute neutrophil count ANC greater than and equal to 1.0109 per liter L; b Platelets 50109L without transfusion support within 7 days; c Hemoglobin 8 gram per deciliter gdL without transfusion support within 7 days; d Prothrombin time International normalized ratio PTINR less than equal to 1.5Upper Limit of Normal ULN and activated partial thromboplastin time aPTT 1.5ULN 