 Neuropsychological Evaluation The cognitive functionality at baseline and its possible worsening after anesthesiasurgery, i.e. the development of POCD, is best evaluated through the administration of neuropsychological test batteries. During the baseline evaluation a neuropsychologist will administer to the patient or to the subject in the Control group a battery of tests standardized to evaluate specifically different cognitive domains: memory, attention, language, executive functions, speed of information processing. The obtained raw scores will be corrected for age, gender and education and transformed, according to Italian calibration standards, in standardized scores Equivalent Scores ES on an ordinal scale that ranges from 0 to 4, where 0 represents scores below the cut-off, i.e., pathological scores, 1 that represents borderline scores and 2,3 and 4 which characterize normality. 