 The patients with the following criteria will be excluded: co-infection with HIV Human Immunodeficiency Virusassociated with a CD count 200mm3 and a viral charge 5000 HIV RNA copiesml, documented iodine intolerance, respiratory disease, decompensated cirrhosis Child-Pugh score over or equal 8, bilirubin concentration over 51μmoll, portal or hepatic vein thrombosis, extra-hepatic metastasis, excessive alcohol intake over 50g per day, blood platelet count below 50,000mm3, neutrophil count below 1500mm3, creatininemia over 120μmoll, other severe concurrent disease, previous treatment for hepatocellular carcinoma and women who can be pregnant or breastfeeding. 