 - Patients must have the following clinical laboratory values: ANC count 1500mm3; Platelets 100,000mm3; Serum creatinine 2x upper limit of normal. If serum creatinine is above the upper limit of normal but less than 2x normal, patients must have a measured 24 hour urine creatinine clearance 50 mlmin to be eligible; Total bilirubin 1.5x upper limit of normal; Serum calcium 12.0 mgdl; Alanine aminotransferase ALT and aspartate aminotransferase AST 3x the upper limit of normal; Prothrombin Time PT, activated partial thromboplastin time aPTT and INR in the normal range;. Hemoglobin 9 gmdl may be corrected by transfusion. 