 Every consecutive adult with temperature 38C attending the outpatient department of Mwananyamala Hospital will be screened for inclusion. Additional inclusion criteria are fever of 1 week duration and first consultation for the present problem. Exclusion criteria are refusal of HIV screening, main complaint is injury or trauma, antibiotic treatment during the previous week apart from cotrimoxazole prophylaxis, delivery within the previous 6 weeks and hospitalization during the last month. Medical history will be taken including exposure to IAP and clinical examination will be done in a standardized way. 