 Current Helicobacter Pylori infection preferred treatment involves; proton pump inhibitor PPI-based triple or qudrable regimens. Omeprazole, Amoxicillin, and Clarithromycin is one of a global standard care for confirmed H.pylori infection . Metronidazole MTZ is used instead of Amoxicillin or Clarithromycin in cases of allergy or resistance . 