 Evaluation of the psychometric characteristics of the FAST was based on 3 primary data analyses: 1 test-retest reliability based on the intraclass correlation coefficient; 2 construct validity based on Spearman correlation coefficients; and 3 responsiveness based on changes in FAST scores. The mean and maximum severity of flushing events, as measured by the FAST, were the primary variables evaluated in each of the 3 data analyses mentioned above. Psychometric analyses were performed blinded to treatment group assignment. 