 The current study aimed to develop and assess an easy-to-use, highly accessible mobile and web-based application intervention to reduce sedentary behavior and increase physical activity in the hope of reducing the side effects of treatment and improving quality of life for the 13,000 or more prostate cancer survivors who are prescribed ADT each year in Canada. The study was conducted in two phases, where Phase one was focused on finding out about the attitudes and perceptions of sedentary behavior and the use of mobile applications among prostate cancer survivors using semi-structured interviews. Together with professional experts and a group of men who were diagnosed with prostate cancer, we developed RiseForTx - an application that is used on a smartphone or tablet to reduce time spent in, and to change patterns of, sedentary behaviour each day Phase two. Part of the intervention was also focused on increasing daily steps to improve physical activity. We tested the intervention to examine i how the application works, ii if prostate cancer survivors like it and use it; and iii if sedentary behaviour and physical activity can reduce the impact of the side effects for treatment and improve quality of life among men on ADT. 