 The goal of the investigators project is to define the genetic causes of this phenotype. The technique of high throughput sequencing will be used to obtain the sequence of exomes of these patients and their families. This study will therefore be important to give an accurate diagnosis for patients and their families. Moreover, investigators believe that this project will identify new genes involved allowing a better understanding of the pathophysiology. Recent studies show the involvement of mutations in several genes eg Shank, NLGN, NRXN and UPF3 in these different clinical phenotypes. However, the genetic basis of the childs schizophrenia are much less well known than those of autism spectrum disorder. 