 The groups and randomization according previous information in summary. In the NICU both groups will receive skin-to skin care by mother Kangaroo Care according to the routine care of the NICU, The mothers will be instructed to perform one stage at a time, and will be supposed to end the sequence within 15 min, four times per day with an interval of 6 hours.The tactile stimulation will be performed on the cutaneous surface and the muscular area corresponding to the temporal, frontal, periorbital, nasal and perilabial regions of the face; the external side of the upper and lower limbs; and the soft parts of two or three fingers grouped will be passed gently with moderate pressure, up to three times in one direction and three times in the opposite direction. The kinesthetic stimulation will consist of passive exercises flexion and extension of upper and lower limbs, one limb at a time and up to three times at each articulation wrist, elbow, ankle and knee; one of the hands supporting the stimulated limb and the other hand performing the movements. 