 2. Analyses after stratification into subgroups Subjects will be grouped according to their BMI, semen quality, serum RANKL, OPG, calcium, PTH, osteocalcin or other bonefactors evaluated at the day of screening. The subgroup analyses will in accordance with normal clinical practice and stratification in appropriate groups according to the clinical BMI 25, 25-30, 30 etc., tertiles or highestlowest versus remaining at baseline. Analyses will be performed on each timpeoint compared with baseline in addition to meanmedian of visit day 80, 120, 180 with baseline and meanmedian of all visits after intervention. 