 This is a multicenter, open label, randomized study to compare the effects of an antihypertensive strategy using a thiazide diuretic as first-line, versus the use as initial therapy of other antihypertensive treatments. All the analyses will be performed by personel blinded to treatment. The study will be performed in collaboration with the Società Italiana Medicina Generale SIMG, Sezione Campania, and the Società Italiana Ipertensione Arteriosa SIIA, Sezione Campania. 