 - Patients must have measurable disease, defined as at least one lesion that can be accurately measured in at least one dimension longest diameter to be recorded for non-nodal lesions and short axis for nodal lesions as 20 mm with conventional techniques or as 10 mm with spiral computed tomography CT scan, magnetic resonance imaging MRI, or calipers by clinical exam; malignant lymph nodes will be considered measurable if they are 15 mm in short axis 