 I. To measure the expression of vascular endothelial growth factor VEGF, fibroblast growth factor FGF, platelet-derived growth factor PDGF, transforming growth factor-beta TGF-B, activin receptor-like kinase 1 ALK1, cluster of differentiation 105 CD105, and other markers via immunohistochemistry IHC and determine if there is correlation between expression and clinical response to treatment. 