 This clinical trial was conducted following the principles of the Declaration of Helsinki. The local authorized clinical trials ethics committee approved the protocol and consent forms Afyon Kocatepe University Clinical Trials Ethics Committee, 2011-KAEK-2 2017172. Between 2015 and 2016, 38 pseudophakic participants ranging from 45 to 65 years of age and previously undergone cataract surgery, no prior Nd: YAG laser posterior capsulotomy and pan-retinal laser photocoagulation PRP, were enrolled in this study. Posterior capsule opacification PCO diagnosis of patients undergone cataract surgery at least 2 years ago were diagnosed by refractive surgery and retina specialists at ophthalmology department of Afyon Kocatepe University. Requirements of Nd:Yag laser posterior capsulotomy of each participants were decided by consensus of 3 ophthalmologists. After providing information to patients about the disease and treatment, patients predicted to show adherence to treatment, were enrolled in the study. 