 Ethical considerations There are no side- or adverse-effects to be foreseen in connection with the intervention. All the patients are managed by dentists or specially trained dental hygienists according to best clinical practice during and after the project. A rapid development of caries will be managed by non-operative and operative treatment irrespective of group. All treatment will be carried out without costs for the families. The tablets are distributed free of charge. All adverse events related to the treatment provided will be recorded on an adverse event form. The investigation will be performed according to the principles of the Declaration of Helsinki on experimentation involving human subjects. 