 - Adequate bone marrow, liver and renal function as assessed by the following: Hemoglobin 9.0 gdl; Absolute neutrophil count ANC 1,500mm3; Platelet count 100,000mm3; Total bilirubin 1.5 x upper limit of normal ULN; Alanine transaminaseAspartic transaminase ALTAST 2.5 x the ULN 5 x ULN for patients with liver involvement; International normalized ratio INR 1.5 or a prothrombin timepartial thromboplastin time PTPTT within normal limits; Creatinine 1.5 x ULN 