 - Underlying hematologic cytopenias e.g., baseline thrombocytopenia, or severe anemia, or leukopenia as determined by the following limits from a baseline CBCCMP obtained within the past 14 days. Note that if a CBC has not been performed within the past 14 days, a CBC will be performed on the day of enrollment prior to any study drug being administered to ensure the patient does not meet exclusion criteria. Cytopenias are defined as: 