 300 women in the third trimester of a singleton uncomplicated pregnancy, who attend a low risk obstetric surveillance group 1. 100 women hospitalized at the Antenatal department due to pregnancy related hypertensive disorder, IUGR, diabetes mellitus, or premature labor will also be recruited group 2. 200 women of a singleton uncomplicated full term pregnancy will be recruited during labor at the delivery room group 3. Neonates born to women from group 1 and 2 group 4. 