 - All adult patients i.e. 18 years of age who are enrolled at NorthEast Rheumatology at the Carolinas Medical Center - NorthEast who will be initiating MTX as standard treatment for their particular rheumatic disease, which may include but not be limited to conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, inflammatory-bowel disease related arthropathies, lupus systemic lupus erythematosus, cutaneous lupus erythematosus, Sjogrens syndrome, Behcets disease, systemic sclerosis, and vasculitides. 