 In addition, in 2012 the PI conducted a population-based cluster randomized trial Self-collection Modality Trial, initials EMA in Spanish. The study was the first carried out in a programmatic, real-world context of a low-resource region with the main objective to assess the effect on women s screening uptake of HPV self-collection offered by CHWs during home visits and to assess the self-test acceptability by women and CHWs. Our intervention resulted in a four-fold increase in screening uptake 85.9 vs 20.2, showing that offering HPV self-collection at home visits through CHWs is an effective strategy to improve cervical screening coverage10. 