 This study will therefore be important to give an accurate diagnosis for patients and their families. Moreover, investigators believe that this project will identify new genes involved allowing a better understanding of the pathophysiology. Recent studies show the involvement of mutations in several genes eg Shank, NLGN, NRXN and UPF3 in these different clinical phenotypes. However, the genetic basis of the childs schizophrenia are much less well known than those of autism spectrum disorder. 