 Furthermore, an intention-to treat analysis will be performed and in both arms both the proportion of resected patients and the 3 year survival will be determined the latter by continued follow-up of all recruited - resected and nonresected - patients beyond the formal conclusion of the present proposal. To detect a difference in resection percentage between both arms of 15 with a power of 87 60 in CTPET group vs 75 in CT-only group, a0.2, one-sided 75 patients are needed in each study arm. The number of 150 recruited patients 2x75, is a realistic estimate of the number of patients that can be included in a 3 year period. This means that at the time point of study closure we will be able to detect A a difference in disease free survival of 25 power 80, a0.05 between patients resected in both study arms and B a difference in resection percentage between both arms of 15 power 87, a0.2. 