 Less than 100 ml of blood will be drawn from each participant at baseline week 0, week 12 and week 24. All blood drawings will be performed at Loma Linda University Medical Center. Participants will report to the laboratory on the assigned days after fasting for a minimum of 12 hours. Body weight and body composition measurements percent body fat, fat free mass, total body water will be obtained at each clinic visit using an internally calibrated segmental bioelectrical impedance analysis device Tanita, Arlington Heights, IL. 