 Number of Subjectsassignment to Formula Groups In these departements about 50 patients are operated for colorectal disease yearly with laparoscopic approach. All these patients are potential candidates to partecipate in the study. It is expected that at least 80 of the patients will agree with partecipation, while during the course of the study about 25 of the partecipants are expected to withdraw. During the intake procedure the inclusion and exclusion criteria are checked. Eligible patients are informed about the objectives, the background and the design of the study. When the patient has given his or her consent to partecipate in the study, the preoperative status is assessed. The patients are then included in the study population and randomly assigned to one of the treatments. During surgery the intraoperative exclusion criteria are checked and non eligible patients excluded from further study. Each group consist of 15 patients in order to assure that at the end of the study 10 patients per group will have completed the study. 