 Intramuscular injections of botulinum toxin are currently the best focal treatment of spasticity, with clearly defined indications and role. French and European recommendations focus on the toxins mode of administration, which must be as precise as possible. The toxins specific action on motor endplates blocking the release of acetylcholine shows the importance of targeted injections within the muscle belly. The pain caused by these injections is due partly the number of injections up to 30 in a single session, and partly to the use of electrical stimulation guidance. Prevention and alleviation of the pain caused by these injections have become a regulatory obligation since the law of 4 March 2002 relating to the rights of patients and the quality of the health system Any person has the right to receive relief from pain, which must, under all circumstances, be prevented, evaluated, taken into account and treated ... . 