 - Concurrent conditions and history of other diseases: 1 Immunocompromized eg, lymphoma, acquired immunodeficiency syndrome, Wiskott-Aldrich Syndrome or have a history of malignant disease within 5 years before the baseline visit; 2 Chronic or acute infection requiring treatment with systemic antibiotics, antivirals, antiparasitics, antiprotozoals, or antifungals within 4 weeks before the baseline visit; 3 Active acute bacterial, fungal, or viral eg, herpes simplex, herpes zoster, chicken pox skin infection within 1 week before the baseline visit; 4 Any other concomitant skin disorder eg, generalized erythroderma such as Nethertons Syndrome, or psoriasis; pigmentation, or extensive scarring that in the opinion of the investigator may interfere with the evaluation of AD lesions or compromise subject safety; 5 Presence of AD lesions only on the hands or feet without prior history of involvement of other classical areas of involvement such as the face or the folds; 6 Other types of eczema. 