 - Patients must have adequate organ and marrow function within 14 days as defined below: absolute neutrophil count 1,500micro platelets 75,000micro Hgb 9.0 gdL may be transfused or receive epoetin alfa permitted total bilirubin 2.0 mgdL albumin 3.0 gdL serum creatinine 2.0 mgdL aspartate aminotransferase AST or SGOT andor alanine aminotransferase ALT or SGPT 2.5 upper limit of normal ULN, no liver metastases ASTSGOT andor ALT SGPT 5 ULN, liver metastases present. 