 STATISTICAL ANALYSIS PLAN Descriptive statistics will be used to characterize the individuals search. The analysis of continuous variables will be through measures of central tendency and dispersion; categorical variables will be analyzed using proportions. The difference between proportions will be calculated using the chi-square test. Association tests will be performed. For correlations, the Pearson or Spearman tests depending on the normality of information or number of empty cells are proceeded. Additionally, the risk factors are analyzed according to the cutoff score of quality of life. We will use multivariate linear regression to verify association between risk factors and QoL. FIT equations will be done. There will be also analysis by protocol and by intention to treat. Analyzes stratified by age also compose the statistical plan. The information collected will be fed into a database and analyzed using SPSS 20.0 software Statistical Package for Social Sciences. Statistically significant values with an interval of confidence greater than or equal to 95 will be considered. 