 Patients with DLBCL who are otherwise healthy are usually treated first with the chemotherapy drug combination called R-CHOP. The drugs in this combination are R for rituximab, C for cyclophosphamide, H for doxorubicin which has a chemical name of hydroxydaunomycin, O for vincristine which has a trade name of oncovin, and P for prednisone. Depending on the local practice where you are treated, R-CHOP may be given for 6 or 8 cycles. A cycle could lasts for 14 or 21 days. The R-CHOP drug combination is approved for the treatment of DLBCL of all types, including ABC type. R-CHOP is standard care. 