 - hemoglobin 9.0gdL; absolute neutrophil count 1,500μl; platelets 100,000μl; total bilirubin 1.5 X upper limit of normal ULN, ASTSGOTALTSGPT 2.5 X ULN, 5 X ULN if known hepatic metastases; Urine protein:creatinine ratio 1.0; creatinine clearance 50 mLmin1.73 m2; PTINRPTT 1.2X ULN 