 7 Established endophthalmitis at time of screening patients with visual symptoms should have ophthalmology review prior to enrollment 8 Established central nervous system abscess at time of screening patients with focal neurology should have CT head prior to enrollment 9 Women who are pregnant or breastfeeding 10 Inability to obtain consent from subject 11 Patients on tizanidine or theophylline 12 Patients on concomitant drugs that can result in prolongation of the QT interval e.g., class IA or class III antiarrhythmics or with risk factors for torsade de pointes e.g., known QT prolongation, uncorrected hypokalemia 13 Patients whose K. pneumoniae tests resistant to ciprofloxacin, and those with contraindications to ciprofloxacin will be tested for G6PD deficiency, and excluded if deficient 14 Severe immunocompromise e.g., active leukemia or lymphoma, generalized malignancy, aplastic anemia, solid organ transplant, bone marrow transplant within 2 years of transplantation, or transplants of longer duration still on immunosuppressive drugs or with graft-versus-host disease, congenital immunodeficiency, current radiation therapy, HIVAIDS with CD4 lymphocyte count 200 and patients or on immunosuppressant medications 15 Creatinine clearance 15 mlmin 