 There is an urgent need to evaluate new therapeutic options in recalcitrant Atopic Dermatitis AD and Allergic Contact Dermatitis ACD. Very few of the available drugs for recalcitrant Atopic Dermatitis AD and Allergic Contact Dermatitis ACD have reasonable efficacy and safety profiles in this condition, are easily available, or easy to administer. A new treatment strategy is needed for the treatment of recalcitrant contact or atopic dermatitis that would increase efficacy, minimize toxicity for both short and long-term treatment, and be easy to administer. The availability of alternative drug treatments offering safe and effective short and long-term management would significantly benefit subjects with recalcitrant contact or atopic dermatitis. 