 Study Methods Overview: Using a web-based randomization system patients, research coordinators will assign critically ill adults treated with antiviral medication for or equal to 72 hours and requiring mechanical ventilation to one of two treatment strategies rosuvastatin or placebo for 14 days. Given the need to recruit patients into the CHAT Trial under pandemic conditions, when family members may not be present to provide written informed consent, we will request either a waiver of consent or deferred consent from Research Ethics Boards REBs at participating centres. The Keenan Research CentreLi Ka Shing Knowledge Institute St Michaels Hospital, Toronto, Ontario will be the study Methods Centre. 