 - 1patients to be diaginsed according to DSM-IV for paranoid schizophrenia;22049 years old;3Duration of 2 10 years;4the disease situation is stable, the fluctuation of PANSS total score 10 in last 1 month, and have accepted the current drugs for more than 8 weeks; 5Patients, their families and doctors are agreed that the disease situation is stable and maintainthe current drug treatmentdrug in next month;6Signed an informed consent 