 - Known ER, PR and HER-2 status FISH assay to be done on specimens with 2 or 3 immunohistochemical staining for HER-2: patients with gene amplification on FISH study will be considered to be HER-2 positive. Patients for this study must be FISH negative if immunohistochemical stain is 2 or 3 positive; patients with negative, 0 or 1 immunohistochemical stain for HER-2 are eligible. 