 - Steroid-dependent CD: CDAI or mCDAI of 150 while receiving prednisone 10-40 mgday or budesonide 3-9 mgday for at least 12 weeks prior to screening, but unable to taper prednisone below 10 mgday or budesonide below 3 mgday without experiencing a flare within the previous 6 months. Steroids must be at a stable dose for 2 weeks prior to screening week -2, prednisone at a dose of 10-40 mgday and budesonide at a dose of 3-9 mgday. 