 - Have acute or chronic hepatitis or elevated liver function tests alanine transaminase, a history of chronic or recurrent pancreatitis. Have renal disease or a serum creatinine blood test 2 milligrams per deciliter mgdL. If taking biguanides e.g. metformin or Glucophage, or DPP-IV inhibitors e.g. Sitagliptin or Januvia or Janumet, creatinine must be 1.5 mgdL. 