 4.2.3 Evaluation of Quality of Life and patient-reported complains, outcomes and satisfaction Patients will be invited to answer the WHOQoL bref Annex 2. They will also answer a questionnaire regarding their believes, expectations and spontaneous complaints before and after treatment Annex 3. This questionnaires will be answered by the patients in the visits: screening, 2, 3, 4 e 5. . 