 Following three doses of hypofractionated palliative radiation Days 2, 1, and Day 0 prior to Cycle 1, patients will receive the combination of tremelimumab 75 mg IV infusion and durvalumab 1500 mg IV infusion on Day 1 for 4 cycles. Beginning with Cycle 5 through Cycle 12, patients will receive durvalumab alone 1500 mgIV infusion on Day 1 of each 28 day cycle. 