 The purpose of the study is to determine whether Granulocyte Colony Stimulating factorG-CSF therapy is effective in the treatment of patients with Acute on chronic liver failureACLF. The investigators hypothesize that ACLF is a disease where severe hepatic impairment is accompanied by impaired hepatic regeneration. BMC mobilization using G-CSF therapy, or G-CSF therapy per se would increase the regenerative capacity of the liver and shall lead to clinical, biochemical and histological improvements in patients with ACLF. 