 - The UPCR has been found to correlate directly with the amount of protein excreted in a 24 hour urine collection. Specifically, a UPCR of 1.0 is equivalent to 1.0 gram of protein in a 24 hour urine collection. Obtain at least 4 ml of a random urine sample in a sterile container does not have to be a 24 hour urine. Send sample to lab with request for urine protein and creatinine levels separate requests. The lab will measure protein concentration mgdL and creatinine concentration mgdL. The UPCR is derived as follows: protein concentration mgdLcreatinine mgdL. Patients must have a UPCR 1.0 to allow participation in the study. 