 - informed consent, histological diagnosis of cervical carcinoma epidermoid, adenoesquamous and adenocarcinoma, clinical stage III B, untreated, aged 18-70 years, performance status 0-2 according to ECOG classification, and adequate liver, hematological and renal function, as defined by: hemoglobin 10 gL, leukocytes 4000mm3, platelets 100 000mm3; normal creatinine value and creatinine clearance 60 mLmin; total bilirubin 1.5 upper normal limit value; no evidence of systemic disease or para-aortic lymph node involvement. 