 Comparative, multicentre, randomised clinical trial, designed with two parallel groups that will follow a treatment either with an autologous implant of ASCs Adipose Derived Stem Cells and fibrin glue tissue adhesive material or with fibrin glue alone for the NON-SURGICAL treatment of complex perianal fistula. The closurehealing of the fistula will be evaluated periodically, and it will be considered completely closed if there is no suppuration from the external orifice and re-epithelialisation can be observed at 8 weeks after the administration of the randomised therapy. 