 11. Has co-morbidities that could affect the esophagus eosinophilic esophagitis, esophageal varices, scleroderma, viral or fungal infection, esophageal strictures, a history of radiotherapy or cryotherapy for the esophagus; those with corrosive or physiochemical injury with the possible inclusion in the study of those with Schatzkis ring or Barretts esophagus. 