 The time window for enrolment will be within 3 to 48 hours of symptom onset. For patients who are found with stroke on awakening, it will be assumed that the stroke occurred the last time that the patient was known to be normal. All eligible patients will be identified by the ward and on-call NeurologyMedical teams and referred to the study research assistants or investigators; who will then screen the patient for participation in this trial. 