 Infants often experience undesirable gastrointestinal effects, such as constipation, flatulence. These symptoms are often perceived by the parents as being related to the diet formula the baby is consuming. In another hand, infantile colic or fussingcrying is one of the most commonly encountered problems within the first three months of life. The etiology of the disorder remains unknown however, three main theories have been proposed to explain its origin: i psychological: due to inadequate mother-infant interaction ii gastrointestinal: such as hypertonicity and immaturity of the GI tract and Dietary factors that may influence the stool pattern in formula fed infants are iii allergic: due to a reaction against cows milk protein or other food constituents. e.g. the protein source, the iron content, hydrolyzation of the protein, or the fat source. 