 In blood of 12 volunteers the following measurements are performed at baseline and 60 dilution with HES 1300.42, Gelatin or Gelatin balanced: Blood gas analyses, coagulation factor concentrations F II,F VII,F VIII,F XIII, impedance aggregometry and rotational thrombelastometry ROTEM. Then FBG, F XIII and a combination of both was added, in concentrations corresponding to 6 g FBG and 1250 IU F XIII in adults. ROTEM measurements and determination of factor concentrations are again performed. 