 - Patients must have histologically or cytologically confirmed metastatic or recurrent squamous cell carcinoma of the headneck; these include tumors arising in the oral cavity, oropharynx, nasopharynx, hypopharynx, glottis, or ethmoidmaxillary sinus; patients with localized disease must have failed primary therapy radiotherapy, surgery, andor chemotherapy; patients with single site or regional recurrence that, in view of the Principal Investigator PI or treating physician is potentially curable by resection or by re-irradiation program, must have declined such therapies 