 Peritoneal dialysis PD is one of important way of renal replacement treatment worldwide. In China, about 40,000 patients suffered from end stage renal disease treated with PD, and almost of them followed continuous ambulatory peritoneal dialysis CAPD because of the expensive price of import automated PD APD machines although the higher clearance of solute, lower rate of PD related peritonitis and higher quality of life QOL in patients treated with APD compared those with CAPD. Now, cheaper domestic APD machines PDGO, Fuzhou, China are accessed to the ESRD patients in china, but the efficacy and safety of which are not fully clear. This will be a prospective, randomized, controlled, multi-center study. Patients in treatment group will receive APD while those in control group will receive CAPD for 8 weeks. After followed-up for 8 weeks, the adequacy of PD, residual kidney function , peritoneum function and QOL of patients will be evaluated. 