 1. Recruitment and screening visit: each subject will undergo a general examination. The ocular examination includes visual acuity, intraocular pressure, biomicroscopy and fundus examination, visual field Humphrey 242 SITA-STANDARD and measurement of the thickness of the optic nerve fiber layer using optical coherence tomography OCT 3 Zeiss. In order to assess the cardiovascular phenotype, the cardiovascular examination will be completed, by an electrocardiogram, an ambulatory blood pressure monitoring, and echocardiography. A blood sample will be also analyzed: lipid analysis, hemogram, ionogram, glucose, cholesterol, triglycerides. A polysomnography will be performed for all subjects for the diagnosis of OSA, and the calculation of a respiratory disturbance index RDI, sleep apnea defined as a RDI 15 per hour. 