 During the bleeding episode prophylactic dose heparin will be administered by continuous infusion 120 mg d 1-2mgkgd, starting at 6 hours after the administration of vitamin K. After 48 hours without clinical signs of hemorrhagic activity with no macroscopic blood remnants will start the treatment of choice at thehospital. Patients randomized to VKA receive will warfarin. Patients receiving acenocoumarol will take warfarin. Patients randomized to receive LMWH will receive bemiparina Hibor to maintain an a-Xa levels between 0.4-1.0 U ml. 