 Placebo will consist of 50 ml NSaline infused over 15 minutes as for the zoledronate regime PLUS calcium 600mg daily Caltrate, one tablet and ergocalciferol 1000 IU daily Ostelin, one capsule. Patients with low vitamin D levels 60 nmolL and parathyroid hormone Pth levels above normal 6.5 should receive ergocalciferol 5000 U daily. 