 - Baseline LVEF 50 measured by echocardiography or MUGA performed within 4 weeks prior to randomisation. History of documented congestive heart failure, angina pectoris requiring antianginal medication, evidence of transmural infarction ECG, poorly controlled hypertension systolic 180 mmHg or diastolic 100 mmHg; clinically significant valvular heart disease; high-risk uncontrolled arrhythmias 