 The goal of this study is to prospectively describe the longitudinal trajectory of functional status, comorbidity, and quality of life from before the initiation of chemotherapy to 6 months after the completion of treatment in older 65 and older and younger under 65 adults. We will determine the effect of pre-treatment physical functioning on physical recovery ie, physical function at end of chemotherapy and 6 months later after the course of adjuvant chemotherapy. In addition, we will explore if factors other than chronological age functional status, comorbid medical conditions, nutritional status, psychological state, cognitive function, and social support predict which patients are more likely to experience treatment morbidity defined as grade 3-5 toxicity, hospitalization or urgent care visits, dose reduction or delay, or premature discontinuation of the planned chemotherapy course 