 - Patients taking short-acting oral analgesics eg, acetaminophen, aspirin, ibuprofen, ketorolac within 6 hours before administration of study drug; long-acting nonsteroidal anti-inflammatory drugs NSAIDs eg, naproxen, oxaprozin, piroxicam, celecoxib within 3 days before administration of study drug; systemic steroids within 72 hours before administration of study drug; or any opioid analgesics or tramadol daily for greater than 10 days of the last 30 days before administration of study drug. 