 Blood samples. 10 ml venous blood will be collected into Ethylenediaminetetraacetic acid EDTA and gel with clot activator -containing tubes from the enrolled patients in all study participants. The concentrations of serum creatinine, troponin, creatine phosphokinase CPK, hemoglobin, triglycerides TG, total cholesterol TC, high-density lipoproteins HDL, low-density lipoproteins LDL, glucose, c-reactive protein CRP, b-type natriuretic peptide BNP and hemoglobin A1c HbA1C will be measured by automatic biochemistry analyzer. 