 Introduction 3-17 of heterosexual couples trying to conceive will be faced with fertility problems Boivin et al, 2007. Of these couples 50 will be confronted with a female factor, which includes amongst others ovarian failure WHO, 2000. Ovarian failure can occur pre-maturely i.e. before the age of 40 years old, in 1 of women; Coulam, 1982; Coulam et al., 1986 or at a physiologically natural age of after 40 years but before reaching the limit of 44 years old at which modern women that still want children can rely on reimbursed medical assisted reproduction MAR in European countries, such as Belgium and the Netherlands. 