 Potentially confounding the SBT, and unstudied, is the effect of position prone, supine, lateral. Similar to adults, infant position has a significant effect on the efficacy of spontaneous breathing. Infants in the CCHS NICU are routinely cared for in multiple positions prone, supine, lateral throughout the day. What is unknown is the impact of infant positioning on the SBT. An SBT performed in one position may not predict infant respiratory status after extubation in another position. Understanding the impact of infant positioning and work of breathing indices independently or in combination with an SBT will aid clinicians in decision-making and potentially decrease neonatal morbidity inaccuracy with timing and safety of extubation. This pilot study will begin to explore these clinically relevant factors. 