 - serum creatinine 1.6 mgdL in female patients or 1.9 mgdL in male patients, aspartate aminotransferase andor alanine aminotransferase 3 x upper limit of normal ; platelet 100.000fL; hemoglobin 8.5 gdL; white blood cell count 1000fL; lymphocyte 500fL; total bilirubin 2.0 mgdL 