 The investigators will address the hypothesis that portal hypertension is mediated in part by bacterial or endotoxin translocation and the production of inflammatory mediators tumor necrosis factor-α TNFα, etc.. The investigators hypothesize that food supplementation with the probiotic product VSL3 in patients with Child Pugh BC cirrhosis will have a beneficial effect on in portal pressure as measured by the HVPG by reducing inflammatory mediators and improving systemic and splanchnic hemodynamics. 