 Patients who complete four months of chemotherapy, will be treated with chemoradiation 50.4Gy in 28 fractions. In the absence of local disease progression deemed inoperable, or metastatic disease progression, patients will be offered surgical resection. Patients who did not receive four months of systemic therapy in the neoadjuvant setting will be offered four months of adjuvant therapy at the discretion of their treating physicians. 