 GPs are required: 1 to record a full medical history, including smoking and drinking habits, based on a pre-defined clinical record; 2 to collect demographic and anthropometric measures height, weight, waist circumference at the iliac crest; 3 to perform a complete physical exam. At baseline and at each visit thereafter, seated office blood pressure will be measured in triplicate using a manual sphygmomanometer according to international guidelines. Measurements will be rounded to the closest 2 mmHg interval. 