 The objective of this study is to assess the safety and efficacy of the Paclitaxel-eluting PTCA-balloon catheter 3μgmm2 balloon surface area in the treatment of significant 70 and 100 stenoses in native coronary arteries with reference diameters from 2.25 mm to 2.8 mm and 22 mm in length for procedural success and preservation of vessel patency. 