 - A female is eligible to enter and participate in this study if she is of: 1 Non-childbearing potential i.e., physiologically incapable of becoming pregnant, including any female who is post-menopausal -OR- 2 Child-bearing potential, has a negative serum pregnancy test at screen, and agrees to one of the following: Complete abstinence from intercourse from 2 weeks prior to administration of the study drug, throughout the study, and for at least 2 weeks after completion or premature discontinuation from the study to account for elimination of the investigational drug. Should a patient decide to become sexually active during the course of the study, she must be counseled and be willing to use one of the birth control methods listed below: Double barrier method male condomspermicide, male condomdiaphragm, diaphragmspermicide; Any intrauterine device IUD with published data showing that the expected failure rate is 1 per year not all IUDs meet this criterion; Sterilization female patient or male partner of female patient; Any other methods with published data showing that the lowest expected failure rate for that method is 1 per year. 