 Until now, the major drawback in applying screening for CYP2C9 polymorphisms to warfarin dosing and VKORC1 genotyping has been slow turnaround time. However, the HPCGG will be able in the Nomogram Development Trial to offer turnaround within 24-48 hours. This rapid turnaround time will allow initial immediate anticoagulation with once or twice daily injectable agents for several days. Therefore, prior to the initiation of warfarin, there will be sufficient time for the genetic information to be received and implemented by the clinical team. 