 Methods. Evaluate 240 consecutive patients with a first ischemic stroke with NIHSS 5-20 without aphasia and with a previous independent functional status mRS 3. Patients will be randomized into four arms: 1 control group, 2 treatment with citalopram 20 mg day, 3 group levodopa sinemet plus100 mg day, 4 group levodopa sinemet plus 100 mg day citalopram 20 mg day. 