 4. After the first 24 hours of treatment, the total methadone dose will be summed and that dose divided into two doses, given 12 hours apart. Subsequently, PRN doses of 0.05 mgkgdose may be given every 6 hours for scores 8 X 2 and added to the next 24 hours doses, divided every 12 hours, until NAS scores are consistently 8 for 48 hours. 