 - FCBP must either agree to use and be able to take effective contraceptive birth control measures Pearl Index 1 or agree to practice complete abstinence from heterosexual intercourse during the course of the study and for at least 1 month after last application of study treatment. A female subject is considered to be of childbearing potential unless she is age 50 years and naturally amenorrhoeic for 2 years, or unless she is surgically sterile. 