 3. Age 60 and amenorrhea for 12 or more months in the absence of chemotherapy, tamoxifen, toremifene, or ovarian suppression and FSH and estradiol in the postmenopausal range according to the local laboratory reference. Note: For women with therapy-induced amenorrhea, serial measurements of FSH andor estradiol are needed to ensure postmenopausal status. OR Preperimenopausal if treated with goserelin that was initiated at least 4 weeks prior to randomization. 