 11. All female subjects will be considered to be of childbearing potential unless they are postmenopausal at least 12 months consecutive amenorrhea, in the appropriate age group and without other known or suspected cause, or have been sterilized surgically. For female participants and female partners of childbearing potential, willingness and able to use two forms of highly effective contraception methods e.g. oral contraceptive and condom, intra-uterine device and condom while on study and for 30 days after the last study treatment. For male participants or male partners of childbearing potential, willingness and able to use two forms of highly effective contraception methods e.g. oral contraceptive and condom, intra-uterine device and condom, while on study and for three months after the last study treatment. 