 - Patients with lymphoma or lymphoproliferative disease B-cell malignancies, or multiple myeloma accepted for referral to the Cancer Family Clinic of the Department of Human Genetics for genetic counseling, or to the MSKCC outpatient clinics of the Lymphoma, Multiple Myeloma, or Leukemia Services in the Department of Medicine in consultation for treatment who are found on routine history or through a Family History Questionnaire FHQ Appendix A to have relatives or members of successive generations of the family affected with Hodgkins disease, non-Hodgkins lymphoma, lymphoid leukemia, multiple myeloma other lymphoproliferative disease prostate or pancreatic cancers. Patients with lymphoma, associated with colon and renal cancer will be eligible for DNA storage through this protocol. Family members or probands with Hodgkins disease who are women who received therapeutic irradiation for Hodgkins disease or who developed secondary cancers after Hodgkins disease are also eligible for participation. 