 - Patients with histologically proven intracranial glioblastoma multiforme GBM or gliosarcoma GS, anaplastic astrocytoma AA, anaplastic oligodendroglioma AO, anaplastic mixed oligoastrocytoma AMO, or malignant astrocytoma not otherwise specified NOS will be eligible for this protocol; patients will be eligible if the original histology was low-grade glioma and a subsequent histological diagnosis of a malignant glioma is made 