 Fractures of the humeral diaphysis occur in a bimodal distribution and represent 3-5 of all fractures. Overall the incidence is higher in women and typically presents at a more advanced age in this population, rendering fixation more difficult due to osteoporosis. The majority of fractures of the humeral diaphysis occur in the mid-shaft and proximal third and the majority are simple or non-comminuted in pattern. 