 Part A of the study will enroll SLE without GN non-renal subjects into 3 cohorts 6 AMG 811: 2 placebo. All subjects will receive a dose of AMG 811 or placebo every 4 weeks beginning with Day 1 D1 for a total of 3 injections. Subjects will be followed through to study day 197, 5 months from the last dose of study medication. 