 - MUGA scan or echocardiogram within 3 months prior to entry if: age greater than or equal to 60, or history of hypertension, or plan to receive trastuzumab. For any patient who has a MUGA scan or echocardiogram performed for any reason, the baseline LVEF must be greater than or equal to LLN for the facility performing the procedure and there must be no regional wall abnormalities 