 Analyses of all samples collected will be conducted in the CUH andor UCCTeagasc laboratories. On some occasions the analyses may be done in collaboration with a third party outside UCC including pharmaceutical companies, which may require samples to be shipped to this organisation. These samples will be coded and identified only using anonymised sample identifier numbers. In addition samples may be stored and used for analysis in future studies. Again samples will be coded and identified only using anonymized sample identifier numbers. 