 Nucleoside reverse transcriptase inhibitors NRTIs are a class of anti-HIV Human Immunodeficiency Virus drug that can be an important part of an HIV treatment regimen. Because anti-HIV therapy may have negative side effects, there is a great need to carefully study HIV infected patients on such regimens. One negative side effect observed in many HIV infected patients is lipoatrophy, a condition that results in fat loss in the body. It is unclear if NRTIs also have a role in the development of mitochondrial toxicity, a condition that affects the bodys ability to produce energy. The purpose of this study is to observe the effects of an NRTI-based, protease inhibitor PI-sparing drug regimen on fat loss in HIV infected, treatment-naive adults. 