 This is a multicenter study conducted at multiple sites, open label all people know the identity of the intervention, randomized the study medication is assigned by chance, parallel-group each group of participants will be treated at the same time study. Approximately, 60 participants will be enrolled in the study. This study will consist of a screening phase maximum 14 days, an observation phase 92 days, and a follow-up phase 98 days. Participants will be randomly assigned to treatment group A, B, or C. During the observation phase, participants will receive injections of paliperidone palmitate of concentration ranging from 75 to 150 milligram equivalents in the deltoid muscle or gluteal muscle as applicable on Days 1, 8, 36, and 64 alternating between sides leftright. Safety evaluations will include assessment of adverse events, clinical laboratory tests, electrocardiogram, vital signs, physical examination, injection site reaction, drug-induced extrapyramidal symptoms scale, and visual analog scale which will be evaluated throughout the study. The total study duration for each participant will be approximately 190 days. 