 - Arm A -- 3 cycles of docetaxel 80 mgm2 intravenous i.v. repeated on day d. 22; followed by 3 cycles of CEF cyclophosphamide 600 mgm2 i.v., epirubicin 75mgm2 i.v., 5-fluorouracil 600 mgm2 i.v., repeated on d. 22 