 Interleukin-2 IL-2 increases the number of CD4 cells in HIV-1 infected patients with a CD4 cell count over 200mm3, but its activity in patients with treatment failure and low CD4 cell counts is unknown. This study will test the efficacy and safety of IL-2 with an optimized antiretroviral regimen in patients with a CD4 count below 200mm3 and a plasma viral load above 10,000 HIV RNA copiesml. 