 Eligible Fabry patients are investigated one ambulatory overnight respiratory polygraphy oRP. For this reason, the subjects are asked to pick-up and learn the self-administration of the oRP device ApneaLinkTM Plus ResMed. The oRP itself is easily performed at subjects home. The following day, the patients need to return the device, or, alternatively, they can send it by post. After oRP, there is no need for further visits for purpose of the study. The subjects are informed about the results of oRP during the next regular clinical follow-up visit. 