 Patients will be stratified based on a baseline CD4 i of less than 150 and ii more than 150 and b sputum smear grading i of 0 ,1 and ii 2 , 3 and randomized to receive one of the three regimens mentioned above, for a period of 6 months, using restricted block scheme. The treatment assignment list will be generated before the start of trial and sequentially numbered sealed opaque envelopes, containing the treatment assigned will be prepared independently in Chennai and Madurai. Assignment of patients to regimens will be done by the study statistician who has no link with the patient. 