 In addition to the prevailing health facility-based TB care, the use of volunteer CHWs and self-administered treatment were found to be appropriate options for pilot testing. Based on our criteria, care by family members had the least operational feasibility because the costs involved to families labour cost from interruptions of daily activities and transport cost and the health systems health worker time and cost of training could be high. Operational difficulties were also anticipated in setting up an appropriate system for monitoring of anti-TB drugs used, provision of health education, referral, monthly reporting of treatment outcome particularly among family members who could be in remote parts of the region. 