 Patients will be randomized to the interventional LAA occlusion group A or NOAC treatment group B in a 11 ratio, the randomization will be done using web-based randomization software. The software is designed to respect the CHA2DS2VASc characteristics of patients, i.e., the goal is to have comparable CHA2DS2VASc in both arms at the end of the study. The randomization process will be done outside all participating centers and therefore it will be masked from study subjects and site personnel. 