 - Inability to interrupt aspirin or other nonsteroidal anti-inflammatory drugs NSAIDs 2 days before, the day of, and 2 days after the dose of Alimta. If a patient is taking a NSAID Cox-2 inhibitors included or salicylate with a long half-life, it should not be taken 5 days before, the day of, and 2 days after the dose of Alimta. 