 - 2. Patient is HIV-positive and has treatment-experienced virologic failure or documented resistance. Treatment-experienced virologic failure is defined as patients meeting the following criteria; 1 previous experience with antiretroviral therapy from at least two of the approved antiretroviral classes i.e. treatment with a nucleoside reverse transcriptase inhibitor, andor non-nucleoside reverse transcriptase inhibitor, andor protease inhibitor for three to six months; 2 increasing HIV RNA after treatment had previously lowered viral load to low or undetectable levels; 3 increasing viremia HIV RNA 5,000 copiesmL in at least two viral load tests confirming their failing regimen. A patient does not need to currently be on therapy. A patient that is currently on a stable antiretroviral regimen that is successfully suppressing or maintaining viremia at low detectable levels HIV RNA 5,000 copiesmL is not eligible for entry into the study. 