 Outcomes The primary outcome of interest is death or major disability at two years of age. Secondary outcomes all at two years of age include: death; disability; and components of disability: neuromotor disability; disability due to seizures; hearing disability; visual disability; communicative disability; cognitive disability. All types of disability are categorised into majornon-majorno disability. The investigators used two questionnaires; the Health Status Questionnaire HSQ was completed by a pediatrician and the Parent Questionnaire PQ was completed by a parent or carer. A third questionnaire, the Short Health Status Questionnaire SHSQ, was developed by the Project Management Group in order to capture the primary outcome for difficult to find children. These questionnaires were sent to general practitioners or health visitors. 