 Infants eligible for the study will be divided into two arms according to oxygenation index: Infants in arm A OI 20 will receive nebulized Iloprost in a lower dose 50 ngkgmin for one hour, and a higher dose 100 ngkgmin for another hour. Infants in arm B OI20 will receive NO, and in addition will receive nebulized Iloprost in a lower dose for one hour and a higher dose for another hour. 