 Evaluation criteria to assess cognitive toxicity have been selected on the basis of the recommendations from C. Meyers and P. Brown, who propose an adapted test battery to evaluate memory, verbal function, visual and motor coordination, and executive function. The selected tests have been validated, also in French. They comprise HVLT-R Hopkins Verbal Learning Test Revised, COWAT Controlled Oral Word Association Test, Grooved Pegboard test, TMT A and B Trailmaking tests A and B, and MMSE. The calculation of patient numbers was based on the HVLT-R test, as memory is thought to be the most frequently affected domain. 