 There are only limited randomized clinical trials assessing the usefulness of CGMS in reducing the rate of diabetes related pregnancy complications with conflicting results 19, 20. Murphy et al. 19 showed in 71 pregnant women with Type 1 and 2 diabetes mellitus that intermittent 4-6 weeks interval CGMS resulted in a significant reduction of HbA1C at 32-36 weeks of gestation, lower birth weight, and reduced risk of macrosomia odds ratio 0.36, 95 confidence interval 0.13 to 0.98, P0.05 compared to standard antenatal care. However, this study was hampered by small sample size and both study groups differed in composition e.g. 5 set of twins in the intervention group as opposed to none in the control group. In contrast, a recently published study 20 of 154 pregnant women with preexisting diabetes mellitus randomized to either real time CGM for 6 days at 8,12,21,27 and 33 weeks of gestation or routine care only showed neither an improvement in glycemic control, reflected in similar rates of hypoglycemia events and HbA1C levels, nor a reduction of large for gestational age neonates rate in the CGM group. In a recent study, Wei et al. included a total of 106 women with GDM in gestational weeks 24-28 were randomly allocated to the antenatal care plus CGMS group or the self-monitoring blood glucose group 21. The authors showed The proportion of GDM women with excessive gestational weight gain was lower in the CGMS group than in the self-monitoring blood glucose SMBG group 33.3 vs. 56.4, P0.039, and women who initiated CGMS earlier gained less weight P0.017. In addition, the investigators showed that the mode of blood glucose monitoring adjusted OR 2.40; 95 CI 1.030-5.588; P0.042 was an independent factor for weight gain. 