 Methods: Single-center, randomised, double-masked, double-dummy, cross-over-study of 96 non-obese BMI 27 kgm2 Caucasian T2DM-patients. After a one month run-in on diet-only treatment, patients were randomised to either repaglinide 2mg three times a day t.i.d. followed by metformin 1g twice a day b.i.d. or vice versa each for a period of four months with a one month wash-out between interventions. 