 - At least 50 of the controls will have the CEP72 promoter variant TT genotype at rs924607 or a coding variant in CEP72 that is predicted to be damaging CADD score 9. The balance of controls will either have variants in other genes that are associated with vincristine neuropathy identified in the ongoing GWAS of 1250 St. Jude Life ALL survivors, or will not have a known genetic variant altering the risk of neuropathy. 