 5. A deep respiratory secretion specimen must be collected within 48 hours prior to randomization and after development of clinical signs and symptoms of VABP ideally prior to administration of systemic antimicrobial therapy. This can be obtained via BAL including protected BAL or mini-BAL, PSB, or ETA, pleural fluid, or lung parenchyma open-lung, transthoracic, or transbronchial biopsy. 