 The patients at the preadmission clinic will receive two bottles of the medication or placebo: One containing 17 X 0.5 mg tabs i.e. 11 tabs plus 6 extra tablets for a 3-day window period for the first week of titration; the other one containing 66 X 1.0 mg tabs 28 days X 2 tablets 56 tablets plus10 for a 5-day window period for the next 4 weeks of treatment. We will call the patients one week before TQD to remind them to start the treatment. In case of delayed or cancelled surgeries, TQD will not change and the patient will continue the treatment according to the above mentioned schedule. The patients will be asked to return the first medication bottle with the remaining pills on the day of surgery. 