 The study will be conducted in Geha Mental Health Center. A total of 80 adolescent non-psychotic smokers will be recruited for this study. A smoker is defined as a cosumer of at least 5 cigarettes daily. A total of 80 patients will be recruited from the adolescent psychiatric wards or the adolescent clinics of the mental health center. The study group N40 will receive bupropion SR and the control group N40 will receive placebo medication. Age of participants will range from 13-20 years. Both genders will be included and all ethnic origins. 