 In the present study, we tested a novel approach to understanding infant bottle-feeding interactions: experimentally manipulating bottle-feeding conditions to better understand maternal and infant influences on overfeeding, as well as individual differences in risk for overfeeding. Specifically, we observed mother-infant dyads during a typical, mother-led feeding, during which mothers were given no instruction regarding how or how much to feed their infants hereafter referred to as a typical feeding TF, as well as during an infant-led IL feeding, wherein we minimized the mothers influence on the feeding and ensured the feed was in response to the infants hunger and fullness cues. Using this within-subject, objective, and experimental approach, the present study aimed to: 1 directly measure the extent to which overfeeding occurs during bottle-feeding and 2 describe the characteristics of infants and mothers that overfeed during bottle-feeding. 