 Target enrollment was 30 eligible patients. An 80 objective response rate at 1 month restaging after 6 cycles was considered as evidence of activity in this patient population while 60 was not considered activity. If at least 22 patients achieved objective response the treatment would be considered promising. With 30 eligible patients, the probability of observing this was 0.87 assuming a true rate of 80 and 0.09 assuming a true rate of 60. 