 Risk of infectious agent Known Human immunodeficiency virus, hepatitis B or C. Known exposure to HIV or viral hepatitis Known current communicable disease High risk lifestyle factors Factors which increase risk of Creutzfeldt-Jakob disease. Gastrointestinal co-morbidities History of inflammatory bowel disease History of IBS History of gastrointestinal malignancy or polyposis History of major Gastrointestinal surgery Factors that can or do affect the composition of the intestinal microbiota. Antibiotics within the preceding 3 months Major immunosuppressive medications Systemic anti-neoplastic drugs Additional recipient specific considerations Recent ingestion of a potential allergen where recipient has a known allergy. Systemic autoimmunity Atopic diseases Chronic pain syndrome Obesity. 