 PETCT also allows the noninvasive study of various biologic processes in tumor tissue. Among various types of radiotracers synthetized to detect brain tumors, 11C-MET is a well-established PETCT radiotracer for brain tumor detection and delineation. Because of its comparatively low background activity in normal brain tissue, 11C-MET PETCT differentiates nontumorous lesions from malignant lesions with high sensitivity and specificity. Though the overall sensitivity for 11C-MET PETCT is from 76 to 100, the sensitivity is lower in studies with higher proportions of non-enhancing low-grade gliomas8. 