 - Any of the following laboratory values: Serum alanine aminotransferase ALT and aspartate aminotransferase levels 10X upper limits of normal, Serum creatinine 2.0 mgdL, Platelet count 60,000mm3, Serum albumin 2.8 gdL, INR 1.7, Direct bilirubin 2.0 mgdL 