 - wait under an adjuvant or neoadjuvant chemotherapy according to the following conventional scheme: 3 cycles of F5-Fluorouracil, epirubicin and cyclophosphamide 100 500 or 5-Fluorouracil 600 mg m2 J1, Epirubicin 100 mg m2 J1, Cyclophosphamide 500 or 600 mg m2 J1 or 3 cycles of Epiribucin and Cyclophosphamide 100 followed by 3 cycles of docetaxel, 100 mg m2, - trastuzumab if Her2 