 51 patients with cataract were included in this study that started at December 2014 to April 2016. All cases collected from out patients clinic of Assiut University Hospital These patients were randomized into two groups. Group Icontrol included 11 cases 22 eyes used Balance Salt Solution BSS eye drops. Group II include 40 cases 67 eyes were treated by the prepared eye drops of urea NPs solution. 