 - Active hepatitis B or C with uncontrolled disease; NOTE: a detailed assessment of hepatitis BC medical history and risk factors must be done at screening for all patients; hepatitis B core immunoglobulin M antibody HBcIgM Ab, hepatitis B surface antigen HBsAg and hepatitis C antibody screen HCV Ab Scrn wreflex testing are required at screening for all patients with a positive medical history based on risk factors andor confirmation of prior hepatitis B HBV infection 