 The effect of BoNT-A injected into other striated muscle is known to have an onset within 3-4 days and duration of action of 6 weeks. The patients will therefore be followed up at 1, 4, and 10 weeks following treatment with flowmetry and ultrasound residual volumes and IPSS questionnaire. The pre intervention investigations of cystometry, urine flow rate if voiding and residual volume measured by ultrasound, urethral pressure profile will be repeated at 4 weeks. Sphincter EMG will only be repeated in patients who have shown a highly significant response i.e. restoration of detrusor contraction in women who previously had complete urinary retention or elimination of post void residual volume in women with obstructed voiding. 