 Pediatric patients with febrile neutropenia coming to Department of Medical Oncology with low risk features culture awaited, will be started on intravenous antibiotics Inj Cefoperazone Sulbactam Amikacin on outpatient basis. Those patients will be reassessed for randomization once they fulfill all inclusion criteria and get afebrile for at least 24 hours. Antibiotics will be stopped in Arm-A and oral antibiotics, in place of intravenous antibiotics, will be started in Arm-B. The patients will be followed-up till ANC 500, or reappearance of fever within follow-up of 10 days. 