 The effects on endometrial thickness will be determined by Transvaginal Ultrasound TV-USG at study baseline and again after 6 cycles of treatment in all women participants. Scans were performed with a real-time scanner, Hitachi 405ultrasound system equipped with a 5.0-megahertz MHz vaginal transducer, at the Vale do Sapucai University. An endometrial thickness 4 millimeters mm will be interpreted as not supporting a diagnosis of endometrial cancer. 