 Exclusion criteria: part time work 90; allergyhypersensitivity to components of the study product; severe respiratory allergy; a situation which, in the investigators opinion, could interfere with optimal participation or constitute a special risk for the volunteer; a history of chronic metabolicgastro-intestinal disease except appendectomy; surgeryintervention requiring general anesthesia in the last 4 weeks; administration of systemictopical treatments likely to interfere with the evaluation parameters in the last 4 weeks; chronic disease requiring antibioticsantisepticsanti-inflammatory medications; special medicated diet; chroniciatrogenic immunodeficiency; cardiacrenalrespiratory insufficiency; severe evolutivechronic pathology; pregnancy, breast feeding or lacking effective contraception in females; susceptibility not to comply with dietary recommendation during the study period. 