 2. Time elapse since commencement of acute pancreatitis symptoms 10 days. In order to take advantage of the window of opportunity to prevent the progression of transient MOF to permanent MOF, patients should be started on enteral feeding as soon as possible. However, in practice many patients present initially with mild disease which progresses to severe necrosis at the end of the first week, and these patients need nutritional support for long periods of time. Consequently, this is an important group to include in this investigation. Post hoc analysis will be performed to see whether they behave differently to patients fed earlier in their disease 