 To assess the effect of ablation therapy on Barretts esophagus. Proposal Ablation therapy is an FDA approved treatment to decrease cancer risk in Barretts esophagus mucosa. This is being performed in our Barretts Esophagus Unit on a regular basis. However, the longterm outcomes of this therapy is not established and there are patients who have been treated who later re-develop Barretts mucosa. This study will allow us store tissue samples that can later be used to assess the effect of ablative therapy on Barretts esophagus. 