 The VibrentTM server has also been securely integrated with the Johns Hopkins Oncospace analytic database server allowing secure one-way secure transmission of out of clinic assessment data to the in clinic Oncospace analytic database which captures all treatment-related information including all radiotherapy dosimetry information and in clinic treatment toxicities and oncologic and toxicity outcome measures including patient-reported outcomes. Integration is particularly important as the radiotherapy dose, volume and the location of the upper aerodigestive tract that is irradiated can all affect the level of the pain experienced from radiation-induced mucositis. Oncospace was developed to handle all continuous data-points in the dose-volume histogram DVH which summarizes the radiotherapy delivered to specific structures delineated in a radiotherapy plan as a series of analyzable relational tables within a database architecture thus facilitating quantification of the radiotherapy treatment and how it may affect radiation-induced mucositis pain. 