 A randomized controlled design will be used to compare the existing HW-TC with CHW-TC and self-administered treatment. Eligible PTB and PTB- patients should be assigned using random numbers, computer generated by a statistician at regional level. To avoid disproportionate allocations among treatment groups two separate random blocks of 3 for PTB and PTB- are arranged. Two sets of sequentially numbered sealed envelopes for each district will be prepared. Two separate boxes containing sealed envelopes for PTB and PTB- will be given to the head of each district health office. The district recruiting officers should obtain the allocation arm for each patient from these district health office heads. For each district, allocation codes used should be recorded weekly by telephone. A statistician will monitor the quality of assignment by cross checking the original list in the research HQ with the sequence of patients attendance for recruitment. Recruiting officers will be trained using a pre-tested guideline prepared to ensure that standard procedures are applied consistently in screening and informing patients. Written consent should be obtained from every patient following proper counselling, with particular emphasis on tuberculosis treatment and the alternative options of care. Patients who refused the randomly assigned method of TB care should be allowed to select either of the two remaining care options. 