 STATISTICAL ANALYSIS. Planned Statistical Analysis Continuous variables will be expressed as means standard deviations. Categorical variables will be expressed as frequencies and percentages. Fishers exact tests andor Chi-Square tests will be mainly used to compare qualitative variables and Students t-test for quantitative unpaired data. A p-value 0.05 will be considered statistically significant in an exploratory sense. In addition to descriptive statistics location parameters, and univariate analysis, multivariate analyses are planned. Independent variables that will be found associated with PVT in univariate analysis with p0.05 will be used as independent covariates associated with PVT in the next 18 months in the multivariable logistic regression analysis. A two-sided p 0.05 was defined as statistically significant. Analyses will be performed using SPSS software version 21, Chicago, IL, USA and GraphPad Prism software GraphPad Software, Inc, La Jolla, CA, USA. 