 The objective of this study is to determine if acute pretreatment with simvastatin, an HMG-CoA reductase inhibitor will reduce the post inflammatory response after percutaneous coronary interventions PCI, andor change endothelial function as assessed by peripheral arterial tomography PAT. Percutaneous coronary intervention PCI, commonly known as coronary angioplasty or simply angioplasty, is a non-surgical procedure used to treat the stenotic narrowed coronary arteries of the heart found in coronary heart disease. 