 This study is designed to compare the efficacy of oral paroxetine 10 to 40 mgday initial dose:10 mgday versus placebo administered once daily after evening meal for 8 weeks in children and adolescents with major depressive disorder MDD based on the change from baseline to Week 8end-of-study in the CDRS-R total score in a randomized, double-blind, placebo-controlled parallel-group study. 