 The University of Wisconsin UW Health HIV Care Program has been partnering with the Mulago Hospital Pediactirc Infectious Disease Clinic PIDC for the past five years. The PIDC has well over 5,000 children with HIV that attend this clinic. Approximately 20 of these children have met criteria for ARV treatment under the US PEPFAR Presidents Emergency Plan for AIDS Relief arrangement. A retrospective collaborative UWPIDC study performed at the PIDC examined using genotyping 40 children who failed initial ARV therapy. This study found some different mutations in children who failed the antiretroviral therapy. 