 - Axis I or II comorbidity that by referring mental health professional andor study psychiatrist is primary need of treatment. This will be assessed by the site principal investigator, who has 10 years clinical experience with this population. Hospital discharge summaries and outpatient medical records may be reviewed i.e., adequate trials of mood stabilizing treatments with minimal to no response, prominent self-injurious behavior in the absence of significant mood symptomatology, or atypical cycle patterns to make this decision. 