 A sample of your tumor tissue will be collected for biomarker analysis. If your tumor tissue cannot be reached, you will not be able to participate in this research study. To collect a tumor biopsy, you will have either a CT-guided core biopsy, bronchoscopy, or other type of biopsy such as subcutaneous, cutaneous, or lymph node. You will be asked to stop taking any medication that affects blood-clotting such as aspirin or coumadin before the biopsy procedure. 