 - 65 years of age OR chronic cardiac or pulmonary disorders including bronchopulmonary dysplasia, cystic fibrosis, and asthma , diabetes mellitus and other metabolic diseases, cancer, immunodeficiency, immunosuppression due to underlying disease andor therapy, renal disease, anemia, and hemoglobinopathy, any condition that can compromise respiratory function or the handling of respiratory secretions or that can increase the risk of aspiration 