 - The patient is currently using at least one of the following: at least 60 mg of oral morphineday, or at least 25 mcg of transdermal fentanylhour, or at least 30 mg of oxycodoneday, or at least 8 mg of hydromorphoneday, or an equianalgesic dose of another opioidday as ATC therapy for at least 7 days before administration of the first dose of study drug. 