 Assessments of clinical oral health status, presence of oral opportunistic pathogens and subjective oral health were conducted at baseline, 3 month and 6 month. All assessments were performed in the TWH Day Rehabilitation Center. Compliance was also assessed. Data will be stored on a computer and backed up on a compact disc in the Faculty of Dentistry, The University of Hong Kong. Professor Colman McGrath Principle Investigator will be responsible for its safekeeping. All data will be kept until analyses have been performed and all research manuscripts have been accepted for publication. The data will then be destroyed. 