 This is a study to determine the safety and tolerability of a new medicine RQ10 for gastrointestinal symptoms in Parkinsons disease. The investigators will also begin to look at the effect of this medicine on gastrointestinal problems. The results will determine if future studies are appropriate. In this study, RQ10 will be compared to a placebo a look-alike inactive substance. Participation will include multiple office visits. Approximately 48 people will participate. 