 2. Be a healthy, non-smoking or smoking 10 cigarettes per day female of non-child-bearing potential between 18 years of age and 55 years of age, inclusive. Females may be accepted if they are documented to be surgically sterile e.g., hysterectomy, tubal ligation or post-menopausal amenorrhea 1 year and FSH 25.8mlUmL, cut off from Labcorp with a negative pregnancy test. At least 30 of female. 