 6. History of serious cardiovascular conditions or NY Heart Association NYHA cardiac status Class III or IV, e.g., recent MI, unstable angina, edema, CHF, CAD, CABG, valve disease murmur, stroke, uncontrolled high blood pressure resting 14090 mmHg on 3 occasions, irregular heart rhythm, bundle-branch block, aortic stenosis, resting ST-segment depression 1mm that would preclude exercise testingtraining, or substantially increase risk of a CV-event during exercise, or would limit the subjects ability to participate in exercise training. Treatment with medications for a cardiovascular condition cardiac glycosides, alpha- or beta-blockers. Some antihypertensive medications Ca-channel blocker, diuretic, or ACE inhibitor will be permitted. 