 Omega-3 fatty acids reduce triglycerides TG in a manner similar to fibric acids by lowering hepatic TG release, reducing VLDL production, stimulating lipoprotein lipase and enhancing TG clearance. Although statins are widely utilized among DH patients, our overall population, even those with CHD, have fairly low levels of LDL-cholesterol Krantz et al, 2004. This likely reflects our population that is predominantly Latino with a high incidence of metabolic syndrome. Among our patients, we often achieve LDL-c NCEP targets, yet secondary goals for non-HDL, HDL, and TG are rarely achieved. This is an unmet opportunity given the strong independent contribution of non-HDL McQueen et al, 2008, HDL DAgostino et al, 2008 and TG Nordestgaard et al, 2007, Tirosh et al, 2007 to CHD risk, which may be particularly important in Latino populations. 