 - Patients with any of the following laboratory abnormalities within 14 days of starting study drug: Absolute Neutrophil Count ANC 750 cellsμL 0.75 x 109L Platelet count 50,000μL 50x109L Serum creatinine 2.5 mgdL Aspartate Aminotransferase AST or Alanine Aminotransferase ALT 3.0 x Upper Limit of Normal ULN 