 Given the complexity and duration of medical care that accompanies severe TBI, it follows that the cost of care associated with TBI are immense. It is estimated that total hospital charges for TBI-related admissions in 2010 were 21.4 billion. Beyond hospital charges, it is estimated that TBI costs the US economy 76.5 billion annually with the costs for disability and lost productivity outweighing those of acute medical care and rehabilitation. 