 The main purpose of this study is to assess the safety and tolerability of AZD5847 after receiving oral doses on a single day Part A or after receiving a single oral dose in two periods Part B. For volunteers in Part B, the effect of food on the PK of AZD5847 will also be studied. Another purpose is to evaluate the pharmacokinetics PK of AZD5847 and its metabolites in blood and urine. 