 In the majority of patients with the chronic urticaria, the etiology is unclear, leading to difficulties in treatment and high rates of recurrence. According to the International EAACIGA2LENEDFWAO Guidelines the Dermatology Section of the European Academy of Allergology and Clinical ImmunologyEAACI, the Global Allergy and Asthma European Network GA2LEN, the European Dermatology Forum EDF and the World Allergy Organization WAO in Urticaria, using the Chronic Urticaria Quality of Life Questionnaire in a routine management is the key for a better treatment outcome. To translate this questionnaire into Thai is essential in our subject of interest in order to effectively apply it to local patients. The Thai-version questionnaire will encourage enhanced as well as impactful therapeutic options for Thai chronic urticaria patients. 