 - No active prior malignancy within 3 years of registration with the exception of non-melanoma skin cancer, in-situ cancers, or Rai stage 0 chronic lymphocytic leukemia CLL; if patient is disease free from a prior malignancy between 3-5 years, special consideration can be requested; in these cases, if the risk of recurrence at 5 years is less than 20, and in the opinion of the investigator the prior malignancy will not affect the patients outcome in light of newly diagnosed pancreatic cancer, the patient may be eligible; this will require principle investigator PI review and approval on a case by case basis, and approval will be documented in the medical record; all patients who have been disease free from a prior malignancy for at least 5 years will be eligible 