 - Currently receiving cancer therapy chemotherapy, radiation therapy, immuno- therapy, biologic therapy, hormonal therapy, surgery, andor tumour embolization.The following are allowed: Hydroxyurea for proliferative disease, Corticosteroids, Use of hematopoetic growth factors is permitted at the discretion of the investigator according to published guidelines e.g., National Comprehensive Cancer Network NCCN, American Society of Clinical Oncology ASCO, American Society of Hematology ASH, etc.. The following are NOT allowed: Investigational anti cancer drug within 2 weeks prior to the first dose of GSK525762; Major surgery, radiotherapy, or immunotherapy within 4 weeks of GSK525762 Chemotherapy regimens with delayed toxicity within the last 4 weeks. Chemotherapy regimens given continuously or on a weekly basis with limited potential for delayed toxicity within the last 2 weeks. 