 This pilot clinical trial studies patients genomic sequencing in determining specific treatments, also called Precision Medicine, in patients with cancer that has spread to other parts of the body metastatic andor cannot be removed by surgery. Examining the genetic code of a patients tumor, a mutation a change in the deoxyribonucleic acid DNA sequence of a cell or gene may be identified and matched with available treatment that targets the mutated gene or an alternative treatment that may provide benefit for the patient with the mutation identified. Precision medicine may impacts patients response to treatment by targeting specific mutations and may increase survival and improve quality of life. 