 The patients will be randomized to one of four groups. Groups 1 and 2 will consist of patients undergoing total thyroidectomy with possible central neck dissection but not lateral neck dissection. Patients in Group 1 will have 3 grams of Arista applied diffusely to the wound bed before primary closure. Patients in Group 2 will not have any Arista applied. Per routine, patients in both groups will have a single 10 French Jackson-Pratt drain will be placed within the thyroid bed and removed per a standardized protocol. 