 - Participant must be healthy on the basis of physical examination, medical history, vital signs, and 12-lead ECG incl. QTcF less than or equal to 450 milliseconds msec for males performed at screening and admission to the clinical unit. Minor abnormalities in electrocardiogram ECG, which are not considered to be of clinical significance by the investigator, are acceptable. The presence of Left Bundle Branch Block LBBB, AV Block second degree or higher, or a permanent pacemaker or implantable cardioverter defibrillator ICD will lead to exclusion 