 Multiple organ failure can be related to an infection producing septic shock, in which substances released in the blood cause poor blood flow to the organs. The number of platelets circulating in your childs blood stream is also decreased this is called thrombocytopenia as a result of this condition. Research has shown that certain substances in the part of the blood known as plasma the clear liquid part of the blood not including the red blood cells but holding blood clotting factors can cause the organs to work poorly. The investigators would like to compare these blood responses in children with this condition, receiving a variety of different treatments, for multiple organ failure in other medical centers around the world. The investigators hope to enroll 80 patients into the study. 