 Method: A total of sixty subjects were randomly assigned to two treatment groups. 1. SRP plus placebo gel 2. SRP plus 1.2 ATV gel. Clinical parameters like probing depth PD, relative vertical clinical attachment level RVCAL , relative horizontal clinical attachment level RHCAL, modified sulcus bleeding index mSBI and site specific plaque index were recorded at baseline and then at 3, 6 and 9 months. The radiological assessment of bone defect fill was done at 6 and 9 months, using a computer-aided software. 