 At 4 weeks of follow-up, the drug dosage per day may increase to 10 mg of amlodipine and 60 mg of nifedipine GITS, if blood pressure measured in doctors office cannot be controlled to a level below 14090 mm Hg. If there were no compelling indication, no other antihypertensive drug is allowed during the 2-month trial. All antihypertensive medication should be taken before breakfast from 6-8 clock in the morning. 