 - Serum glutamic oxaloacetic transaminase SGOT aspartate aminotransferase AST or serum glutamate pyruvate transaminase SGPT alanine aminotransferase ALT must be 1.5 x IULN; for patients with liver metastasis, NO total bilirubin outside of normal limits, and NO ALT or AST 2.5 ULN 