 - Patients must meet at least 2 of the following clinical criteria :Hypothermia 36C OR fever 38.5C; Bradycardia OR tachycardia OR rhythm instability; Urine output 0.5 to 1 mLkgh OR hypotension OR mottled skin OR impaired peripheral perfusion; Petechial rash OR sclerema neonatorum; New onset or worsening of apnoea episodes OR tachypnoea episodes OR increased oxygen requirements OR requirement for ventilation support; Feeding intolerance OR poor sucking OR abdominal distension; Irritability; Lethargy; Hypotonia: 