 Medicare beneficiaries will be excluded or censored if they do not have both Part A and Part B coverage, or enrolled in Medicare Advantage plans Part C, as detailed claims for these beneficiaries are not available. We will also exclude dual-eligible Medicare and Medicaid recipients as these subjects have distinct clinical conditions e.g. blindness that distinguishes them from most Medicare beneficiaries. There will be no exclusions based on gender, race, ethnicity, or cognitive impairment. 