 This is a Phase 1, double-blind, randomized participants taste the same groups of drugs formulations but in random order, single-center trial in healthy adult participants. The study will include 2 Sessions of 1 day, 1 Session 1, in which participants will receive 6 JNJ-53718678 oral solutions 1 reference and 5 different formulations sequentially in a randomized order, Scoring of the taste will be done via a questionnaire designed for this purpose; 2 Session 2, within approximately a timeframe of 7 to 14 days after completion of Session 1, participants will taste 2 best scoring tastes coming out of Session 1. The study will consist of a screening phase of approximately 2 weeks, treatment phase of approximately 2 weeks and a post-treatment follow-up phase of 10 days after completion of the last Session. The total study duration for each participant will be approximately 6 weeks. 