 - Female subjects of childbearing potential must be using a medically acceptable form of birth control for at least 1 month prior to screening 3 months on oral contraceptives, e.g oral or patch contraceptives, intrauterine device, NuvaRing, Depo-Provera, or double-barrier and have a negative pregnancy test at Screening and Day 0 of each Dosing Period. Female subjects of non childbearing potential must be amenorrheic for at least 2 years or had a hysterectomy andor bilateral oophorectomy 