 The sample size calculations were based on Pockock, 1983 and three outcome variables were used: Hb level of 11.0 gmdl, standard deviation SD 1.5 gmdl; mean birth weight of 3000gms, SD 500gms; and proportion of women who take malaria prophylaxis in Uganda, currently estimated at 34. To detect differences in Hb of 0.5 gmdl, birth weight of 150gms and a change of 12 in the proportion of women using malaria prophylaxis; between the control and any delivery approach of the study, the sample sizes required are 170, 211, and 310 for the three variables respectively, allowing for a 20 loss of follow up. For this study, the sample size of 310 was taken for each arm giving a total sample size of 1,550. 