 - Alkaline phosphatase 2.5 x ULN 5 x ULN in patient with liver involvement of their cancer. If Alkaline phosphatase 2.5 ULN, hepatic isoenzymes 5-nucleotidase or GGT tests must be performed; hepatic isoenzymes 5-nucleotidase must be within the normal range andor GGT 1.5 x ULN 