 - Women of non-child-bearing potential defined as being 1 year post-menopausal or using effective contraception, e.g., use of oral contraceptives with an additional barrier method since the investigational product may impair the effectiveness of oral contraceptives, double barrier methods diaphragm with spermicidal gel or condoms with contraceptive foam, Depo-Provera, partner vasectomy, or total abstinence, from the time the informed consent is signed through 30 days after the last dose of MEDI-573. Male subjects with partners of child-bearing potential must be surgically sterile or use contraceptive method as described above from the time of the initiation of MEDI-573 through 30 days after the last dose of MEDI-573. 