 6. To be considered at high risk for induction mortality patients must have 1 or 2 of the following risk factors patients 60 must have at least 1 risk factor, patients 60 must have at least 2 risk factors present. At least one risk factor in every patient must be an AML-related factor: AML-related factors include: AHD MDS, CMML, or MPD or history of exposure to cytotoxic chemotherapy t-AML, or WHO-defined AML with MDS-related changes or apparent de novo AML with MDS-associated karyotype; Unfavorable cytogenetics as defined by the European Leukemia Net. Patient-related factors: Age 70; ECOG PS 2; Co-morbidities: Serum creatinine 1.3 gdL . 