 At the procedure visit, patients were randomized to receive a 30-minute 2 minute application of S Caine Peel either on the right or left treatment area and to receive a concurrent 30-minute 2 minutes application of placebo on the alternate treatment area. The point of reference was always the patients right and left. S-Caine Peel and placebo were dispensed to cover the treatment area with a uniform thickness of approximately 1 mm. Study drug was applied to the right treatment area first, then concurrently to the left treatment area. Similarly, the study drug was removed first from the right treatment area and then from the left treatment area. Following removal of the study drugs, the investigator or physician subinvestigator evaluated each study drug application site for erythema, edema, blanching or other skin reactions. The right treatment area was evaluated first, followed by the left treatment area. 