 8. Adequate organ function, as defined by the following: a Total bilirubin 2.0 times the institutional Upper Limit of Normal ULN b Hepatic enzymes AST, ALT 2.5 times the institutional ULN c Serum sodium, potassium, magnesium, phosphate, and calcium levels greater than or equal to the Lower Limit of Normal LLN. d Serum Creatinine 1.5 time the institutional ULN e Hemoglobin, Neutrophil count, Platelets, PT, PTT all Grade 0-1, as defined by the NCI CTCAE v3.0. 