 - Patients must have a platelet count 100,000, ANC greater than or equal to 1500 without transfusion or cytokine support, a normal PT, and adequate hepatic function as evidenced by a total bilirubin of 1.5 times ULN. Serum creatinine less than or equal to 1.6 mgml or creatinine clearance 70 mlmin1.73m2 at the time DACTHU - celecoxib treatment commences. 