 From weaning to age 12 months the clinical data, the adherence to the dietary protocol and the amount of intervention baby-food ingested will be checked every month. Following investigations will be performed at the time of recruitment, at time of weaning and at 12, 18, 24, 30,36, 42, 48, 54 and 60 months by taking a sample of blood maximum 4 ml from infants a quick test for IgA anti-tTG abs determination few drops; b conventional ELISA for serum IgA and IgG anti-tTG determination 0.4 ml;c serum zonulin determination 0.1 ml; e serum sample for T1D-related autoantibodies 0.25 ml; f serum sample to be stocked in the sera bank 0.25 ml; g whole blood sample in EDTA for validation of the quick tests 0.5 ml. All the sera samples will be frozen, stored at -20 C and sent boxed in dry ice in blocks to the centre responsible for the determinations every 2 months. Cases positive for the quick-test for anti-tTG the serum sample will be frozen and immediately shipped for confirmatory determination. 