 Patients will take 15 or 20 mg of A3309 or placebo administered orally for eleven 11 consecutive days and report for post-study medication transit scintigraphy on day twelve 12 of dosing. Study medication will be administered once with the In111 capsule on Visit 4 and once immediately before the camera images obtained on Visits 5 and 6. Study medication will be administered at Charlton 7 CRU by a nurse on days 12-14. 