 Subjects will be instructed to refrain from using any study prohibited drugsmedications both recreational and prescription throughout their participation in the study. After final eligibility is confirmed, subjects who report taking contraindicated medications over the course of the study period may only remain eligible if the Study Physician andor Principal Investigator determines that the contraindicated medications dodid not impact the study design, data quality, andor subject safetywelfare. Subjects are permitted to take necessary prescription medications not included within the exclusion list during the study. 