 The design of the study is a prospective randomised, placebo controlled study that will be carried out on a single site. The study will involve four visits in total over an 8 week period. The first visit will be a screening visit to assess eligibility for the study. Visit two will be the treatment visit at which patients will receive the FMT using stool from a healthy donor or placebo. An autologous faecal microbiota transplant will be used as the placebo in this study. Follow up visits will be performed at 4 weeks and 8 weeks after the treatment. 