 Inclusion Criteria: - Subjects with end stage renal disease ESRD on hemodialysis Exclusion Criteria: - Known hypersensitivity to Aranesp darbepoetin alfa or any of its excipients - Participating in an investigational drug or device trial - Patient will not be available for follow-up assessment - Patient has any disorder that compromises the ability of the patient to give written informed consent andor to comply with study procedures 