 - Unable to refrain from vitamins, herbal and dietary supplements including St Johns Wort within 7 days or 14 days if the drug is a potential enzyme inducer or 5 half lives whichever is longer prior to the SCR visit until the completion of the follow-up assessments, unless in the opinion of the Investigator, in consultation with the GSK MM if required, the medication will not interfere with the study procedures or compromise subject safety. 