 - EXCEPTION: during the DOSE ESCALATION PORTION of the study only, a measurable M-protein 0.5 gdL on serum protein electrophoresis SPEP or a measurable urinary light chain 200 mg24 hrs by urine protein electrophoresis UPEP without a dFLC meeting the above criteria is acceptable; subjects without a dFLC 5 mgdL treated at the MTD will not count towards the expansion cohort 