 This study aims to investigate the effect of a cobiotic formulation, prepared as a smoothie beverage, on the ratio of intestinal microbiota of the Bacteroidetes phylum to those of the Firmicutes phylum in the stool as well as the effect on insulin resistance, gut hormones PYY Peptide YY and GLP-1 Glucagon-like Peptide, ghrelin with perceptions of appetite and satiety. 