 13. Unwilling or unable to do supervised exercise 3 sessionswk at the Medical School exercise facility. Any condition that might be contraindicated for exercise training disabling joint, cartilage or muscle injurydisorder that prohibits or severely limits participation in regular exercise, disabling arthritis, severe physical disabilities, claudication, pulmonary disease, sinus tachycardia, arrhythmias, premature atrial or ventricular contractions. 