 This is an investigational study. Ganetespib is not FDA approved or commercially available. It is currently being used for research purposes only. Paclitaxel, carboplatin, and radiation therapy are all FDA approved and considered standard treatment for esophageal cancer. The combination of paclitaxel, carboplatin, ganetespib, and radiation therapy is investigational. The study doctor can explain how the study drugs are designed to work. 