 - Progression according to 2006 IWG criteria at any time after initiation of AZA or DAC treatment or Failure to achieve complete or partial response or hematological improvement HI according to 2006 IWG after at least six 4-week cycles of AZA or either four 4-week or four 6-week cycles of DAC administered or Relapse after initial complete or partial response or HI according to 2006 IWG criteria 