 - AML in 2nd CR or in first line for high risk criteria, secondary AML. In AML, high risk criteria are defined by : LAM 7, leukocytes30000mm3, cytogenetic abnormalities: t6,9; 11q23, 17p, 11q, 20q, 21q, -5, del5q, -7del7q, del 9q and inv 3q, 