 Dexketoprofen trometamol, is one of the most powerful inhibitors of prostaglandin synthesis in vitro. 12.5-25 mg orally is given with a quickly absorbed on an empty stomach, which has a strong binding to albumin and inactive metabolites after glucuronization renal excretion. It is well accumulate in synovial fluid and its analgesic potency is comparable to 50 mg of ketoprofen or diclofenac and more than 600 mg of ibuprofen, so its main indication is acute postoperative pain. 