 During the conduction of this study all involved trial participants, clinicians, data collectors, event adjudicators, and data analysts will be blinded to the grouping of patients. All study medications will be stored in the hospital pharmacy department by a third party. Following randomization, treatment drugs will be dispensed by the pharmacy and then administered by nursing staff. The third party service will maintain records linking a patient unique identifier to her study group. Post hoc analysis to assess whether staff could identify between the intervention and placebo will be conducted. 