 Following the screening visit within 4 weeks prior to the day of admission, the study will be run over an 8-day period in a confined environment, consisting of the admission day D-2, a 2-day baseline period D-1 and D0, and a 5-day exposure period D1 to D5. Subjects will be discharged in the morning of D6. From the discharge of the subject, a 7-day safety follow-up period will be carried out until D13. 