 6. Patients must meet the following laboratory criteria: ASTSGOT and ALTSGPT 2.5 x upper limit of normal ULN or 5.0 x ULN if the transaminase elevation is due to leukemic involvement; Serum bilirubin 1.5 x ULN; Serum creatinine 1.5 x ULN or 24-hour creatinine clearance 50 mlmin; Serum potassium lower limit of normal LLN; Serum phosphorous LLN; Serum total calcium corrected for serum albumin or serum ionized calcium LLN; Serum magnesium LLN; TSH and free T4 within normal limits WNL patients may be on thyroid hormone replacement 