 - To determine the frequency self-rated spiritual pain scale when score is more or equal than 1 in the scale 0 to 10 and intensity of self-rated spiritual pain in the palliative care setting and to explore the association between spiritual pain, and negative religious coping Brief RCOPE, physical ESAS and psychological symptoms HADS, and primary caregiver distress CQLS-C, caregiver self-assessment questionnaire. 