 Exclusion Criteria: Patients who are pregnant a urine HCG will be performed if a female of child-bearing age is not on reliable birth control, or if otherwise clinically indicated, are currently on therapeutic anticoagulation, have a bleeding disorder, platelet count of less than 100,000mL, coagulopathy, active bleeding, creatinine clearance less than 30 mLmin based on Cockcroft-Gault equation, and rounding serum creatinine to 1 in patients greater than 65 years, or recent within 14 days stroke, surgery or trauma will be excluded. 