 - History of alcoholdrug abuse or dependence within 12 months of the study. Abuse of alcohol defined as an average weekly intake of 14 drinksweek for men or 7 drinksweek for women. One drink is equivalent to 12 g alcohol 5 ounces 150 ml of wine or 12 ounces 360 ml of beer or 1.5 ounces 45 ml of 80 proof distilled spirits. 