 Patients will be randomised to one of 3 arms - Arm A: Faropenem 400mg with amoxicillinclavulanic acid 500mg125mg, each three times daily for 5 days n12 Arm B: Pyrazinamide 2g 1.5g if weight 50kg once daily for 5 days n8 Arm C: Isoniazid 300mg once daily for 5 days n8 Following the 5 days of study medication the study will end and patients will change to standard combination TB therapy and enter normal clinical follow-up. 