 - Positive for at least one of the following autoantibodies typically associated with T1DM: antibody to glutamic acid decarboxylase anti-GAD antibody to protein tyrosine phosphatase-like protein anti-IA-2 or an insulin autoantibody IAA. Please note: A subject who is positive for IAA and negative for the other autoantibodies will not be eligible if the subject has been using insulin for a total of 7days. 