 We propose to evaluate the efficacy and confirm the safety of pulsed dye laser therapy V-Beam laser, Candela Corp., Wayland, MA, 595 nm wavelength used in conjunction with a topical photosensitizer in the treatment of acne vulgaris. This is a split-face comparison study in which one half of the face will be treated with photo-sensitizer and laser, and the contralateral side will be left untreated. Because one proposed mechanism of action for such treatments includes altered sebaceous gland activity, we also seek to examine the effects of this treatment on cutaneous sebum production. 