 Because of the importance of iron chelation in patients with AA and low and intermediate-1int-1 risk MDS complicated with iron overload, it is necessary to monitor their iron overload status to find the suitable patients to be chelated and follow up the effectiveness of therapy. Using quantitative Magnetic resonance imaging MRI T2 to detect the iron deposit of different organs has been introduce to China since 5 years ago. Compared to the traditional methods for evaluating iron overload like clinical manifestations, serum ferritin SF level, transferrin saturation TS, CT and echocardiography UCG etc., which are widely used so far in China, MRI T2 provides an more accurate, convenient and affordable non-invasive way of monitoring iron overload. More important, it is very reliable to monitor the improvement of iron chelation therapy since the variation of MRI detection between different detections is very low. Few reports have been focused on IOL of MDS and AA in China so far. 