 440 women with expected poor ovarian response undergoing IVFICSI intracytoplasmic sperm injection will be randomly divided into 2 groups using computer generated random numbers . Group 1 study group will receive Dehydroepiandrosterone DHEA 25 mg DHEA 25mg, Natrol , USA t.d.s daily for 12 weeks before starting IVFICSI cycle. Group 2 control group will receive a placebo. Patients included in the study will be subjected to full history taking and clinical examination. On the second day of menstruation serum FSH, LH, Prolactin and Oestradiol will be assessed and the antral follicular count AFC will be assessed using a vaginal ultrasound scan. AFC will be defined as the number of follicles measuring 3-10mm. 