 Platelet-rich plasma PRP is a rich source of growth factors. The growth factors present in PRP are familiar, including transforming growth factor-_ TGF-_1 and TGF-_2, vascular endothelial growth factor, 3 isomers of platelet-derived growth factor PDGF-__,PDGF-__, and PDGF-__, and endothelial growth factor. These growth factors are considered to have the capacity to accelerate chemotaxis, mitogenesis, angiogenesis, and synthesis of collagen matrix and support tissue repair when applied on bone wounds. Due to this high platelet content, PRP has been used in orthopaedic surgery, oral implantology, and periodontics with the aim of making the repair process as fast and natural as possible, as it can potentially afford considerable tissue improvement in bone and soft tissue in a similar way. PRP is easily acquired, rich in cell signalling molecules, completely autogenous and can be obtained from minimal blood volumes.the purpose of the present study is to determine the efficacy of PRP in the treatment of mandibular TBC. 