 Five patients six eyes with CNV secondary to AS participated in this retrospective interventional case series. All patients were scheduled for three monthly IVB injections 1.25 mg. Two eyes had been previously treated with photodynamic therapy PDT, and four received IVB as first choice treatment. IVB was repeated in case of recurrence after the three monthly IVB schedule. Ophthalmic evaluations included: best corrected visual acuity BCVA determination ETDRS, optical coherence tomography OCT, fluorescein and indocyanine green angiographies. Main outcome measures were BCVA improvement, reduction of leakage from CNV and diminution of central retinal thickness CRT. Patients were followed-up for 30 months. Patients were 3 males and 2 females aged 44 to 67 years mean 51.6 - 9.07 SD, who received a mean number of 4.33 IB treatments -1.5; min: 3, max: 7. The mean retreatment interval was 3 months -1.36; min: 2, max: 6. 