 The studys primary objective will be to compare, at 1 year of follow-up, the efficacy binary success criteria of partial caries removal versus complete caries removal in occlusal or proximal deep lesions of mature permanent posterior teeth bicuspids and molars except third molars. Secondary objectives will include the comparison, at 1 year of follow-up, of the efficacy binary success criteria of an antibacterial two-step self-etch adhesive versus a traditional non-antibacterial two-step self-etch adhesive. Another secondary objective will be to compare, at two and three years of follow-up, the efficacy of partial versus complete caries removal. 