 The proposed observational, dietary study with cross-over design will assess the independent effects of energy intake i.e. calorie load and fat intake on gastric fullness, the number and severity of reflux and dyspeptic symptoms after meals. The effect of alcohol on symptoms after the high calorie, high fat meals will also be documented. The study population of senior academics attending a conference are likely to have a relatively high prevalence of risk factors for gastro-esophageal reflux disease GERD being predominantly male, with an older age and a larger waist circumference than average in the general community. This will increase study power and relevance of the findings. 