 The production of a unique isomer of ketoprofen formulation simplifies the pharmacokinetics of the drug and allows a reduction of 50 in the dose. This can reduce adverse effects to reduce the metabolic and renal work, rapid absorption appears to offer some protection against gastrointestinal complications as a method to avoid gastrointestinal toxicity different of the selectivity of COX presents a good profile of security and reported adverse effects are similar to placebo in these studies, the uniqueness of the therapeutic profile of the DKP.TRIS could be the result of a combination of factors which include the higher power as it is given only the active molecule, inhibition of COX two isoenzymes, rapid absorption from the gastrointestinal tract and high capacity to enter the CNS. 