 Patients were assigned to two groups: a uncomplicated - composed of hypertensive patients without complications and without other concurrent diseases; and b complicated, including patients with severe hypertension mean diastolic pressure 110 mm Hg with or without medication or comorbidities such as diabetes mellitus 7, renal failure serum creatinine 1.4mgdL, coronary insufficiency, congestive heart failure or prior history of cerebrovascular accident. 