 - A lifetime history of bipolar disorder, schizophrenia, psychosis, or delusional disorders; an eating disorder in the past 6 months; organic brain syndrome, mental retardation or other cognitive dysfunction that could interfere with capacity to engage in therapy; a history of substance or alcohol abuse or dependence other than nicotine in the last 6 months or otherwise unable to commit to refraining from alcohol use during the acute period of study participation. 