 Only healthy volunteers had screening tests such as medical inquiry, physical examination, clinical laboratory test, etc. within 4 weeks -28d -1d prior to drug administration 1d and those determined eligible for this study were selected and randomized between screening and 1 day prior to the first administration of study medication -1d. Then, the subjects were admitted to the clinical research center of Seoul National University Hospital by 9 p.m. of -1d and then, they were not allowed to take anything except water. 