 Substance use including cigarette and illicit drug use and HIV represent major public health problems facing Americas youth CDC, 2007; Johnston, OMalley, Bachman, Schulenberg, 2007. Hispanic adolescents report higher use across all drug categories with the exception of amphetamines and higher cigarette use than non-Hispanic White and African American adolescents Johnston et al., 2007. Hispanic youth also engage in higher rates of unprotected sexual behavior at last sexual intercourse than non-Hispanic White and African American adolescents CDC, 2007. Compared to non-Hispanic Whites, Hispanics are also disproportionately represented among HIVAIDS cases, accounting for 18 if all such cases in the United States CDC, 2006. These disparities are especially disconcerting because Hispanics are the largest and fastest growing minority group in the United States Marotta Garcia, 2003. Preventing substance use and HIV in Hispanic adolescents is therefore if vital importance. 