 After an appropriate period of time following bunionectomy, participants who had a pain intensity score of 40 mm on a 100 mm visual analog scale VAS and moderate or severe pain intensity per the categorical pain intensity scale were eligible for randomization, in equal numbers, into 1 of 5 treatment arms. In order to maintain the single-blind nature of the study, all participants were dosed with study drug active andor placebo every 6 hours. 