 Enrolment to the study will take place at the beginning of the subsequent treatment visit for those patients who consent to take part having had time to consider the information provided about the study at the pre assessment visit. Patients will receive pre sedation instructions. Standard electronic monitoring pulse oximetry, pulse rate and blood pressure will be available to the clinical staff at all times. Standard dental sedation will be used according to the institutions policy and protocol. A capnostream 20 monitor Oridian medical, Needham, MA, using a disposable oral - nasal CO2 cannula capable of delivering oxygen, with an oral sampling port to accommodate mouth breathing will be attached to all patients. The capnostream 20 monitor displays oximetry and CO2 waveform and calculates ETCO2. The capnography monitor will be calibrated every day of the study. 