 A promising approach for the detection of EOC has been established by Paul Speiser and Robert Zeillinger Molecular Oncology Group, Department of General Gynaecology and Gynaecologic Oncology, Medical University of Vienna, Austria. This approach is called the ALPINE technique Austrian Lavage Procedure for the Detection of tubal Intraepithelial Neoplasms manuscript under preparation. It includes a lavage of the uterine cavity and proximal fallopian tubes and subsequent analysis of this lavage fluid for the presence of pre-malignant and malignant cells. 