 In a retrospective analysis of 300 inpatients 152 medical, 148 orthopedic patients of the Cantonal Hospital of St. Gallen our group identified clinical predictors for the loading dose of phenprocoumon and two dosing algorithms were developed Good AC, Henz S. A clinical algorithm to predict the loading dose of phenprocoumon. Thromb Res. 2007;1206:921-5.. 