 All patients fill the follow-up form before procedure. After catheter ablation therapy, all patients invited to come back to the outpatient clinic every week in the first month, and then at 2, 3, 6, 9, and 12 month to follow up. Patients received electrocardiogram and Holter monitor examination if with symptoms of palpitations. Those patients with no symptoms received electrocardiogram every month and Holter monitor examination every 6 months. Recurrence of atrial fibrillation was defined as atrial fibrillationflutter or atrial tachycardia lasting 30 seconds 3 months after radiofrequency catheter ablation therapy. Patients who have AF recurrence within three months after therapy will not be considered for repeated radiofrequency ablation.Blood samples routine blood, high sensitivity c-reactive protein,B-type natriuretic peptide BNP, cystatin C,homocysteine,β2-microglobulin and transthoracic echocardiography indexes left atrial anterior to posterior diameter, left atrial length-diameter,left atrial transverse-diameter,left atrial volume index, mitral e, E peak, A peak, EA,velocity time integral VTI, left atrial ejection fraction, left atrial strain, strain rate and atrial electrical - mechanical conduction time are recorded in all patients at each follow-up. Patients with AF recurrence must have an electrocardiogram or a 24 hour holter monitor evidence. 