 A maximum of 11 mL of blood will be drawn for biomarkers at visits up to 28 days prior to beginning chemotherapy, after receiving at least a cumulative 240 mgm2 of doxorubicin, 6 months - 4 weeks after starting chemotherapy, and 12 months - 4 weeks following starting chemotherapy. Serum Troponin I and BNP levels will be drawn at the same intervals as the echocardiograms. 