 At the procedure visit, patients who met the eligibility criteria were assigned the lowest available sequential patient number. The randomization determined the placement of the S-Caine Peel and placebo with the active study drug applied to either the topright or bottomleft treatment area and the placebo applied to the alternate treatment area. The treatment areas were defined as 2 similar anatomical locations that required similar amounts of dermal filler as measured in mLs injected, and number of injections administered. The point of reference for these designations was the patients right and left or top and bottom. Patients had a concurrent administration of the study drugs, with the appropriate study drug applied to the topright treatment area first followed immediately by the other study drug applied to the bottomleft treatment area. Study drug application was double-blind. The study drugs were applied with a uniform thickness of approximately 1 mm and remained on the skin for 30 minutes - 2 minutes. 