 Platelet Derived Growth Factor PDGF is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. Recombinant human platelet derived growth factor R-PdfGbb has biologic activity similar to endogenous platelet derived growth factor PDGF. Biologic activity of PDGF includes encouraging chemotaxis and proliferation of cells responsible for wound repair and it augments production of granulation tissue. 