 Linkage of the Clinical Practice Research Datalink CPRD to the Myocardial Ischaemia National Audit Project MINAP, Hospital Episode Statistics HES and Office of National Statistics ONS, offers the opportunities to study the natural history of hypertrophic cardiomyopathy, from the time of diagnosis to the end of life, health care utilisation and to investigate the association between clinical characteristics and common clinical fatal and non-fatal outcomes. 