 - If the difference between PWT at Walk 1 and Walk 2 is 25 of the higher of the 2 PWTs, a third treadmill test Walk 3 may be performed at the discretion of the Principal Investigator between 7 and 14 days following Walk 2. The variability in PWT warranting the performance of Walk 3 must be secondary to circumstances that may contribute to the observed variation e.g., prior exertion, inconsistent timing, ingestion of a meal within 4 hours, etc. To qualify for the study, the difference between PWT of either Walk 1 or Walk 2 as compared with Walk 3 must be 25 of the higher of the 2 PWTs higher PWT - lower PWThigher PWT. The decision whether Walk 1 or Walk 2 will be used for comparison with Walk 3 will be made prospectively and reviewed with the Sponsor. 