 - Aged 21 years with clinical atherosclerotic cardiovascular disease ASCVD history of acute coronary syndrome or myocardial infarction, stable or unstable angina, coronary revascularization, stroke, transient ischemic attack TIA presumed to be of atherosclerotic origin, or peripheral arterial disease or revascularization, on a high-intensity statin or moderate-intensity statin if not a candidate for high-intensity statin due to safety concerns; 