 - Patients with known brain metastases are eligible only if heshe has been treated for brain metastasis, are asymptomatic after treatment, have a stable CT or MRI of the brain within 28 days of enrollment and are not receiving corticosteroid therapy to control symptoms from brain metastasis. Only a non-enzyme inducing anticonvulsant e.g., Keppra will be permitted for those patients requiring anticonvulsants. Topical andor inhaled steroids are allowed. 