 - Treated with an SSRI, SNRI, or bupropion at adequate doses defined as 20 mgday or more of fluoxetine, citalopram, or paroxetine; 10 mgday or more of escitalopram; 50 mgday or more of sertraline; 75 mgday or more of venlafaxine; 15 mgday of mirtazapine; or 40 mgday of duloxetine; or 100mgday of bupropionwellbutrin during the current episode for at least 8 weeks; and, 