 Patients undergo bone marrow aspirate and biopsies and blood sample collection periodically for laboratory studies. Samples are analyzed for cytokines i.e., IL-6, TNF-γ, IL-1β, and IL-10 by ELISA; phenotypic, molecular, and functional analysis of immunologic reconstitution markers i.e., PHA, IL-2, IL-4, IL-10, IL-12, Fas, FasL, TNF, TGF-β, and IFN-γ by flow cytometry; and cytogenetics by FISH. 