 - Inhaled Corticosteroid: A well-documented requirement for regular treatment with high dose inhaled corticosteroid ICS in the 12 months prior to Visit 1 with or without maintenance oral corticosteroids OCS. For participants 18 years old: ICS dose must be 880 micrograms mcgday fluticasone propionate FP exactuator or equivalent daily. For ICSlong-acting beta-2-agonist LABA combination preparations, the highest approved maintenance dose in the local country will meet this ICS criterion. For participants 12 to 17 years old: ICS dose must be 440 mcgday FP ex-actuator or equivalent daily. For ICSLABA combination preparations, the mid-strength approved maintenance dose in the local country will meet this ICS criterion 