 - Incidence of POCD at 1 year: the incidence of POCD in patients over 70 years of age, at 1 year after surgery is estimated to be 16. In the very old, given the lack of data in literature, the investigators estimate that the incidence could be around 20, therefore similar to the incidence of POCD at 3 months after surgery. The sample size foreseen for the primary outcome measure 1812 patients provides a power 1-β 0.8 with α 0.05 to detect a 25 relative reduction in this secondary outcome measure. 