 The investigators will undertake a pilot randomized controlled trial in non-bleeding ICU patients who require an invasive medical procedure central venous catheterization, chest tube, thoracocentesis, paracentesis, biopsy, fluid drainage in 3 Canadian hospitals. Patients with an abnormal coagulation test INR between 1.5 to 2.5 will receive a FP transfusion or no treatment prior to an invasive procedure. 