 3. Pathological diagnosis of AML according to WHO criteria with at least 20 blasts in the peripheral blood or bone marrow: Newly Diagnosed De novo AML; except for APL; Newly Diagnosed Secondary AML, defined as having a history of an antecedent hematologic disorder myelodysplastic syndromes MDS, myeloproliferative disease MPD or history of cytotoxic treatment for non-hematologic malignancy or apparent de novo AML with MDS-associated karyotype. 