 15. Subjects with prior hypersensitivity to zonisamide or related compounds, including sulfonamides e.g. sulfisoxazole carbonic anhydrase inhibitors e.g. acetazolamide, sulfonylureas e.g. chlorpropamide, sulfamates e.g. topiramate, thiazide e.g. hydrochlorothiazide, and loop diuretics e.g. furosemide except ethacrycrynic acid. 