 Organizational characteristics: The study will be governed by a Steering Committee chaired by the Principal Investigator Prof. Bruno Trimarco. The study will be performed as a collaborative effort of 260 general practitioners with previous experience in scientific initiatives, specialist centers Community Hospitals and University Hospitals in which specialized evaluation of hypertension related organ damage is routinely evaluated. The Department of Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, division of Coronary Intensive Care Unit and High Blood Pressure Center will act as a Coordinating Center, run by Professor Trimarco, PI. The central database will be stored at this center, and the other specialist centers and GPs will have remote access to it through encrypted login and password. The web-based access to the database has already been implemented at the Coordinating Center, within the Campania Salute Project, a regional network of Community Hospitals and GPs. 