 This is a registry database project; there are no investigational treatments, drug or procedures associated with participation in registry activities. This project is an organized data gathering and storing database endeavor with specific focus on the precursors, modifiers, biological, and genetic parameters of heart disease and related medical conditions. Data collection will not immediately influence the course of treatment for any patient.Sample testing and data utilization for basic science, clinical, and epidemiologic and publication projects can be initiated using the databank. 