 Although consideration of the patients point of view to evaluate the effectiveness and quality of therapeutic strategies and, more widely, healthcare interventions have been imposed for the last 20 years in the investigators healthcare systems, the data on caregivers viewpoints are more recent. Authors concurred that assessing caregivers needs and experiences is a more appropriate source of information to identify their expectations concerning the quality of the healthcare system rather than the concept of patient satisfaction. The impact of MS on the natural caregivers QOL and expectations for the global quality of management is not documented in France, notably because of the lack of adapted tools. So, if caregivers support capacities are exceeded primarily because of their own impaired QOL and their expectations for the quality of management are not considered, the therapeutic contract will be diminished, thereby worsening the overall quality of management for MS patients. 