 In the general population, xerosis is often caused by external factors such as seasonal changes. In that case, the best way to relieve dry skin is to use a standard moisturizer. However, for those suffering of mobility problems due to age or paralysis e.g., spinal cord injury, multiple sclerosis, Parkinsons, etc, xerosis is often severe and chronic because of the multiple causes endogenous rather than exogenous ones underlying such mobility impairment-related skin problems. This study is a double-blind, randomized study with positive control active comparator to assess the safety and efficacy of SQIN with CanSATs Co-Activation of Natural Synergistically Acting Target-receptorS technology on dry skin in patients suffering of paralysis. 