 - Patients with clinically apparent cardiac disease, or history of same, are not eligible; patients who are 60 years of age or who have a history of hypertension must have an echocardiogram or MUGA prior to enrollment; patients with breast cancer that is HER-2neu positive and a treatment plan that includes Herceptin must have an echocardiogram or MUGA scan prior to enrollment; the LVEF must be within the institutional normal range; if LVEF is 75, the investigator should consider having the LVEF reviewed or repeating the MUGA prior to registration 