 4. If UPC 1, then a 24-hour urine protein must be assessed. Subjects must have a 24-hour urine protein value 1 g to be eligible. Use of urine dipstick for renal function assessment is not acceptable. 10. Women of childbearing potential must agree to use effective contraception 11. Negative serum pregnancy test if applicable 12. Affiliated to or a beneficiary of a social security category 