 Patient will be evaluated for latent TB infection with a PPD or a Quantiferon Gold test and CXR. Patient who demonstrates evidence of latent TB infection either PPD more than or equal to 5 mm of induration or positive Quantiferon Gold, irrespective of Bacillus Calmette-Guerin BCG vaccination status and negative CXR findings for active TB, andor suspicious CXR findings will not be allowed to participate in the study. 