 This pilot study will evaluate home vision testing using a mobile medical application in participants with diabetic macular edema DME or neovascular age-related macula degeneration nAMD who receive intravitreal ranibizumab therapy. In the main, decentralized study, participants will be recruited via digital media, advocacy groups, or through their own ophthalmologist. The traditional substudy will evaluate the association between visual acuity and anatomical markers of disease status determined using clinical gold standard assessments certified Early Treatment Diabetic Retinopathy Study ETDRS protocol visual acuity and macula optical coherence tomography OCT and the results of home vision testing using the myVisionTrackTM mVT application. 